- Published
Metformin versus placebo in combination with insulin analogues in patients with type 2 diabetes mellitus: the randomised, blinded Copenhagen Insulin and Metformin Therapy (CIMT) trial
Lundby-Christensen, L., Tarnow, L., Boesgaard, T. W., Lund, S. S., Wiinberg, N., Perrild, H., Krarup, T., Snorgaard, O., Gade-Rasmussen, B., Thorsteinsson, B., Røder, M., Mathiesen, E. R., Jensen, T., Vestergaard, H., Hedetoft, C., Breum, L., Duun, E., Sneppen, S. B., Pedersen, O., Hemmingsen, B. & 6 others, , 2016, In: B M J Open. 6, 2, e008376.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metformin-induced changes of the gut microbiota in healthy young men: results of a non-blinded, one-armed intervention study
Bryrup, T., Thomsen, C. W., Kern, T., Allin, K. H., Brandslund, I., Jørgensen, Niklas Rye, drb459, drb459, Hansen, Torben, Hansen, T. H., Pedersen, Oluf Borbye & Nielsen, T., 2019, In: Diabetologia. 62, 6, p. 1024-1035Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metformin-induced glucagon-like peptide-1 secretion contributes to the actions of metformin in type 2 diabetes
Bahne, E., Sun, E. W. L., Young, R. L., Hansen, M., Sonne, D. P., Hansen, J. S., Rohde, U., Liou, A. P., Jackson, M. L., de Fontgalland, D., Rabbitt, P., Hollington, P., Sposato, L., Due, S., Wattchow, D. A., Rehfeld, Jens Frederik, Holst, Jens Juul, Keating, D. J., Vilsbøll, Tina & Knop, Filip Krag, 2018, In: JCI Insight. 3, 23, p. 1-16 e93936.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Methodology for Accurate Detection of Mitochondrial DNA Methylation
Mechta, Mie, Ingerslev, L. R. & Barrès, Romain, 2018, In: Journal of Visualized Experiments. 135, e57772.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Methods and Guidelines for Measurement of Glucagon in Plasma
Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2019, In: International Journal of Molecular Sciences (Online). 20, 10 p., 5416.Research output: Contribution to journal › Review › Research › peer-review
- Published
Methods in Bioarchaeology: What’s New in Profiling an Individual Inside and Out
Freiwald, C., Belanich, Jonathan Robert & Rand, A., 2022, The Routledge Handbook of Mesoamerican Bioarchaeology. Tieslar, V. (ed.). Routledge, p. 577-600 24 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Methylome and proteome integration in human skeletal muscle uncover group and individual responses to high-intensity interval training
Jacques, M., Landen, S., Romero, J. A., Hiam, D., Schittenhelm, R. B., Hanchapola, I., Shah, A. D., Voisin, S. & Eynon, N., 2023, In: FASEB Journal. 37, 10, 18 p., e23184.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MicroRNA expression profiling of carcinoma in situ cells of the testis
Novotny, G. W., Belling, K. C., Bramsen, J. B., Nielsen, J. E., Bork-Jensen, J., Almstrup, Kristian, Sonne, Si Brask, Kjems, J., Rajpert-De Meyts, E. & Leffers, H., 2012, In: Endocrine - Related Cancer. 19, p. 365-379 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MicroRNAs in Metabolism
Vienberg, S., Geiger, J., Madsen, S. & Dalgaard, L. T., Feb 2017, In: Acta Physiologica (Print). 219, 2, p. 346-361 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MicroRNAs in non-alcoholic fatty liver disease: Progress and perspectives
Hochreuter, Mette Yde, Dall, M., Treebak, Jonas Thue & Barrès, Romain, 2022, In: Molecular Metabolism. 65, 17 p., 101581.Research output: Contribution to journal › Review › Research › peer-review
- Published
Microbial Imidazole Propionate Affects Responses to Metformin through p38γ-Dependent Inhibitory AMPK Phosphorylation
Koh, A., Manneras-Holm, L., Yunn, N., Nilsson, P. M., Ryu, S. H., Molinaro, A., Perkins, R., Smith, J. G. & Backhed, F., 2020, In: Cell Metabolism. 32, 4, p. 643-653.e4 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Microbial dietary protein metabolism regulates GLP-1 mediated intestinal transit
Toft, P. B., Yashiro, H., Erion, D. M., Gillum, M. P., Bäckhed, F. & Arora, Tulika, 2023, In: FASEB Journal. 37, 10, 8 p., e23201.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Microbial evolutionary medicine: from theory to clinical practice
Andersen, Sandra Breum, Shapiro, B. J., Vandenbroucke-Grauls, C. & de Vos, M. G. J., 2019, In: Lancet Infectious Diseases. 19, 8, p. e273-e283 11 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Microbial fermentation of flaxseed fibers modulates the transcriptome of GPR41-expressing enteroendocrine cells and protects mice against diet-induced obesity
Arora, Tulika, Rudenko, Olga, Egerod, Kristoffer Lihme, Husted, Anna Sofie, Kovatcheva-Datchary, P., Akrami, R., Kristensen, M., Schwartz, Thue W. & Backhed, F., Mar 2019, In: American Journal of Physiology: Endocrinology and Metabolism. 316, 3, p. E453-E463Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Microbial metabolite p-cresol inhibits gut hormone expression and regulates small intestinal transit in mice
Toft, P. B., Vanslette, A. M., Trošt, K., Moritz, Thomas, Gillum, M. P., Bäckhed, F. & Arora, Tulika, 2023, In: Frontiers in Endocrinology. 14, 7 p., 1200391.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Microbial regulation of GLP-1 and L-cell biology
Greiner, T. U. & Bäckhed, G. F., Sep 2016, In: Molecular Metabolism. 5, 9, p. 753-8 6 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Microbial regulation of enteroendocrine cells
Arora, Tulika, Vanslette, A. M., Hjorth, Siv Annegrethe & Backhed, F., 2021, In: Med. 2, 5, p. 553-570 18 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Microbial regulation of hexokinase 2 links mitochondrial metabolism and cell death in colitis
Hinrichsen, F., Hamm, J., Westermann, M., Schröder, L., Shima, K., Mishra, N., Walker, A., Sommer, N., Klischies, K., Prasse, D., Zimmermann, J., Kaiser, S., Bordoni, D., Fazio, A., Marinos, G., Laue, G., Imm, S., Tremaroli, V., Basic, M., Häsler, R. & 10 others, , 2021, In: Cell Metabolism. 33, 12, p. 2355-2366.e8Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Microbial regulation of the L cell transcriptome
Arora, Tulika, Akrami, R., Pais, R., Bergqvist, L., Johansson, B. R., Schwartz, Thue W., Reimann, F., Gribble, F. M. & Bäckhed, F., 2018, In: Scientific Reports. 8, p. 1-9 1207.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Microbial translocation in type 2 diabetes: when bacterial invaders overcome host defence in human obesity
Jensen, Benjamin Anderschou Holbech & Marette, A., 2020, In: Gut. 69, p. 1724-1726Research output: Contribution to journal › Comment/debate › Research
- Published
Microbially Produced Imidazole Propionate Impairs Insulin Signaling through mTORC1
Koh, A., Molinaro, A., Stahlman, M., Khan, M. T., Schmidt, C., Manneras-Holm, L., Wu, H., Carreras, A., Jeong, H., Olofsson, L. E., Bergh, P., Gerdes, V., Hartstra, A., de Brauw, M., Perkins, R., Nieuwdorp, M., Bergstrom, G. & Backhed, F., 2018, In: Cell. 175, 4, p. 947-961.e17Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Microbially Produced Imidazole Propionate Is Associated With Heart Failure and Mortality
Molinaro, A., Nemet, I., Bel Lassen, P., Chakaroun, R., Nielsen, T., Aron-Wisnewsky, J., Bergh, P. O., Li, L., Henricsson, M., Køber, Lars Valeur, Isnard, R., Helft, G., Stumvoll, M., Pedersen, Oluf Borbye, Smith, J. G., Tang, W. H. W., Clément, K., Hazen, S. L., Bäckhed, F. & MetaCardis Consortium, M. C., 2023, In: JACC: Heart Failure. 11, 7, p. 810-821 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Microbially produced glucagon-like peptide 1 improves glucose tolerance in mice
Arora, T., Wegmann, U., Bobhate, A., Lee, Y. S., Greiner, T. U., Drucker, D. J., Narbad, A. & Bäckhed, G. F., Aug 2016, In: Molecular Metabolism. 5, 8, p. 725-30 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Microbiome and metabolome features of the cardiometabolic disease spectrum
Fromentin, S., Forslund, S. K., Chechi, K., Aron-Wisnewsky, J., Chakaroun, R., Nielsen, T., Tremaroli, V., Ji, B., Prifti, E., Myridakis, A., Chilloux, J., Andrikopoulos, P., Fan, Y., Olanipekun, M. T., Alves, R., Adiouch, S., Bar, N., Talmor-Barkan, Y., Belda, E., Caesar, R. & 44 others, , 2022, In: Nature Medicine. 28, 2, p. 303-314Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Microbiome-derived ethanol in nonalcoholic fatty liver disease
Meijnikman, A. S., Davids, M., Herrema, H., Aydin, O., Tremaroli, V., Rios-Morales, M., Levels, H., Bruin, S., de Brauw, M., Verheij, J., Kemper, M., Holleboom, A. G., Tushuizen, M. E., Schwartz, T. W., Nielsen, J., Brandjes, D., Dirinck, E., Weyler, J., Verrijken, A., De Block, C. E. M. & 7 others, , 2022, In: Nature Medicine. 28, p. 2100-2106Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Microbiota-Produced Succinate Improves Glucose Homeostasis via Intestinal Gluconeogenesis
De Vadder, F., Kovatcheva-Datchary, P., Zitoun, C., Duchampt, A., Bäckhed, G. F. & Mithieux, G., 12 Jul 2016, In: Cell Metabolism. 24, 1, p. 151-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Microbiota-induced obesity requires farnesoid X receptor
Parséus, A., Sommer, N., Sommer, F., Caesar, R., Molinaro, A., Ståhlman, M., Greiner, T. U., Perkins, R. & Bäckhed, G. F., 1 Mar 2017, In: Gut. 66, 3, p. 429-437 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Middle ear effusion, ventilation tubes and neurological development in childhood
Thorsen, Jonathan Jan Ilve, Pedersen, T. M., Cecilie Mora-Jensen, A. R., Bjarnadó ttir, E., Bager, S. C., Bisgaard, H. & Stokholm, Jakob, 2023, In: PLoS ONE. 18, 1, 14 p., e0280199.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Migration mediated by the oxysterol receptor GPR183 depends on arrestin coupling but not receptor internalization
Kjær, Viktoria Madeline Skovgaard, Daugvilaite, V., Stepniewski, T. M., Madsen, C. M., Jørgensen, Astrid Sissel, Bhuskute, K. R., Inoue, A., Ulven, Trond, Benned-Jensen, T., Hjorth, Siv Annegrethe, Hjortø, Gertrud Malene, Moo, Ee Von, Selent, J. & Rosenkilde, Mette, 2023, In: Science Signaling. 16, 779, 13 p., eabl4283.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mild Cognitive Impairment Is Associated with Poorer Nutritional Status on Hospital Admission and after Discharge in Acutely Hospitalized Older Patients
Bornæs, O., Andersen, A. L., Houlind, Morten Baltzer, Kallemose, T., Tavenier, J., Aharaz, A., Nielsen, Rikke Linnemann, Jørgensen, L. M., Beck, A. M., Andersen, Ove, Petersen, Janne & Pedersen, Mette Merete, 2022, In: Geriatrics (Switzerland). 7, 5, 16 p., 95.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mind the Gut
Whiteley, Louise & Bencard, Adam, 2020, Medical Museion, University of Copenhagen.Research output: Book/Report › Book › peer-review
- Published
Mind the Gut
Bencard, Adam, Gerdes, N., Vilstrup-Møller, N. C., Whiteley, Louise, Bjerregaard, Malthe Kouassi & Thon, C., 2017Research output: Non-textual form › 2D/3D (psysical products) › Research
- Published
Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches
Welsh, J. A., Goberdhan, D. C. I., O’Driscoll, L., Buzas, E. I., Blenkiron, C., Bussolati, B., Cai, H., Di Vizio, D., Driedonks, T. A. P., Erdbrügger, U., Falcon-Perez, J. M., Fu, Q. L., Hill, A. F., Lenassi, M., Lim, S. K., Mahoney, M. Ỹ. G., Mohanty, S., Möller, A., Nieuwland, R., Ochiya, T. & 31 others, , 2024, In: Journal of Extracellular Vesicles. 13, 2, 84 p., e12404.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Minimum information about a marker gene sequence (MIMARKS) and minimum information about any (x) sequence (MIxS) specifications
Yilmaz, P., Kottmann, R., Field, D., Knight, R., Cole, J. R., Amaral-Zettler, L., Gilbert, J. A., Karsch-Mizrachi, I., Johnston, A., Cochrane, G., Vaughan, R., Hunter, C., Park, J., Morrison, N., Rocca-Serra, P., Sterk, P., Arumugam, M., Bailey, M., Baumgartner, L., Birren, B. W. & 78 others, , 2011, In: Nature Biotechnology. 29, 5, p. 415-20 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Minor Contribution of Endogenous GLP-1 and GLP-2 to Postprandial Lipemia in Obese Men
Matikainen, N., Björnson, E., Söderlund, S., Borén, C., Eliasson, B., Pietiläinen, K. H., Bogl, L. H., Hakkarainen, A., Lundbom, N., Rivellese, A., Riccardi, G., Després, J., Alméras, N., Holst, Jens Juul, Deacon, Carolyn F., Borén, J. & Taskinen, M., 2016, In: PLOS ONE. 11, 1, p. 1-15 15 p., e0145890.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mitochondrial function in lamb as a consequence of maternal caloric restriction during pregnancy and high-fat-high-carbohydrate diet post partem
Jørgensen, W., Nielsen, M. O., Gam, C., Scheibye-Knudsen, M., Grunnet, N. & Quistorff, B., 2009, In: Journal of Diabetes. 1, Suppl. 1, p. A81 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Mitochondrial function in liver cells is resistant to perturbations in NAD+ salvage capacity
Dall, M., Trammell, Sam, Asping, M., Hassing, Anna Skab, Agerholm, M., Vienberg, S. G., Gillum, M. P., Larsen, Steen & Treebak, Jonas Thue, 2019, In: The Journal of Biological Chemistry. 294, 36, p. 13304-13326 23 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mitochondrial phosphatidylethanolamine modulates UCP1 to promote brown adipose thermogenesis
Johnson, J. M., Peterlin, A. D., Balderas, E., Sustarsic, E. G., Maschek, J. A., Lang, M. J., Jara-Ramos, A., Panic, V., Morgan, J. T., Villanueva, C. J., Sanchez, A., Rutter, J., Lodhi, I. J., Cox, J. E., Fisher-Wellman, K. H., Chaudhuri, D., Gerhart-Hines, Zach & Funai, K., 2023, In: Science Advances. 9, 8, 15 p., eade7864.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mitofusin 2 in POMC neurons connects ER stress with leptin resistance and energy imbalance
Schneeberger, M., Dietrich, M. O., Sebastián, D., Imbernón, M., Castaño, C., Garcia, A., Esteban, Y., Gonzalez-Franquesa, A., Rodríguez, I. C., Bortolozzi, A., Garcia-Roves, P. M., Gomis, R., Nogueiras, R., Horvath, T. L., Zorzano, A. & Claret, M., 26 Sep 2013, In: Cell. 155, 1, p. 172-87 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mixed-mode chromatography-mass spectrometry enables targeted and untargeted screening of carboxylic acids in biological samples
Hodek, O., Argemi Muntadas, Lidia, Khan, Adnan & Moritz, Thomas, 2022, In: Analytical Methods. 14, 10, p. 1015-1022 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Model-Based Discovery of Synthetic Agonists for the Zn2+-Sensing G-Protein-Coupled Receptor 39 (GPR39) Reveals Novel Biological Functions.
Frimurer, Thomas Michael, Mende, F., Graae, A., Engelstoft, M. S., Egerod, Kristoffer Lihme, Nygaard, R., Gerlach, L., Hansen, J. B., Schwartz, Thue W. & Holst, Birgitte, 2017, In: Journal of Medicinal Chemistry. 60, 3, p. 886-898 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modeling neural tube development by differentiation of human embryonic stem cells in a microfluidic WNT gradient
Rifes, P., Isaksson, M., Rathore, Gaurav Singh, Aldrin-Kirk, P., Moller, O. K., Barzaghi, G., Lee, J., Egerod, Kristoffer Lihme, Belmont-Rausch, Dylan Matthew, Parmar, M., Pers, Tune H, Laurell, T. & Kirkeby, Agnete, 2020, In: Nature Biotechnology. 38, p. 1265-1273 9 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Modeling the early stages of Alzheimer's disease by administering intracerebroventricular injections of human native A beta oligomers to rats
Baerends, E., Soud, K., Folke, J., Pedersen, A., Henmar, S., Konrad, Lisa, Lycas, M. D., Mori, Yuki, Pakkenberg, B., Woldbye, David Paul Drucker, Dmytriyeva, O. & Pankratova, Stanislava, 2022, In: Acta Neuropathologica Communications. 10, 1, 21 p., 113.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modelling cue integration in cluttered environments
Sahani, M. & Whiteley, Louise, 2011, Sensory Cue Integration. Trommershäuser, J., Körding, K. & Landy, M. S. (eds.). Oxford University Press, p. 82-100 (Computational Neuroscience).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Moderate variations in the human diet impact the gut microbiota in humanized mice
Schoeler, M., Chakaroun, R., Brolin, H., Larsson, I., Perkins, R., Marschall, H., Caesar, R. & Bäckhed, F., 2024, In: Acta Physiologica. 240, 3, 17 p., e14100.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modifiable environmental influences on body mass index shared by young adult brothers
Rokholm, B., Silventoinen, K., Tynelius, P., Sørensen, Thorkild I.A. & Rasmussen, F., 2013, In: International journal of obesity (2005). 37, p. 211-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modulation in selectivity and allosteric properties of small-molecule ligands for CC-chemokine receptors
Thiele, S., Malmgaard-Clausen, M., Engel-Andreasen, J., Steen, A., Rummel, P. C., Nielsen, M. C., Gloriam, David E., Frimurer, Thomas Michael, Ulven, Trond & Rosenkilde, Mette, 27 Sep 2012, In: Journal of Medicinal Chemistry. 55, 18, p. 8164-77 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modulation of constitutive activity and signaling bias of the ghrelin receptor by conformational constraint in the second extracellular loop
Mokrosinski, J., Frimurer, Thomas Michael, Sivertsen, B., Schwartz, Thue W. & Holst, Birgitte, Sep 2012, In: Journal of Biological Chemistry. 287, p. 33488-33502 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modulation of gut microbiota by Mantequilla and Melipona honeys decrease low-grade inflammation caused by high fructose corn syrup or sucrose in rats
Coutiño-Hernández, D., Sánchez-Tapia, M., Leal-Vega, F., Bobadilla del Valle, M., Ledezma, H., Cervantes, R., Pedraza-Chaverri, J., Granados-Portillo, O., Díaz, D., Antunes-Ricardo, M., Gutiérrez-Uribe, J., Maya, Otoniel, Olin-Sandoval, V., Tovar, A. R. & Torres, N., 2022, In: Food Research International. 151, 13 p., 110856.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular Connectomics Reveals a Glucagon-Like Peptide 1 Sensitive Neural Circuit for Satiety
Webster, A. N., Becker, J. J., Li, C., Schwalbe, D. C., Kerspern, D., Karolczak, E. O., Godschall, E. N., Belmont-Rausch, Dylan Matthew, Pers, Tune H, Lutas, A., Habib, N., Güler, A. D., Krashes, M. J. & Campbell, J. N., 2023, bioRxiv, 47 p.Research output: Working paper › Preprint › Research
- Published
Molecular Consequences of Peripheral Influenza A Infection on Cell Populations in the Murine Hypothalamus
Lemcke, René, Jensen, Christine Egebjerg, Pagh-Berendtsen, Nicolai, Egerod, Kristoffer Lihme, Thomsen, Allan Randrup, Pers, Tune H, Christensen, Jan Pravsgaard & Kornum, Birgitte Rahbek, 2023, 31 p.Research output: Working paper › Preprint › Research
- Published
Molecular Insights into the Role of Pathogenic nsSNPs in GRIN2B Gene Provoking Neurodevelopmental Disorders
Shah, A. A., Amjad, M., Hassan, J. U., Ullah, A., Mahmood, A., Deng, H., Ali, Y., Gul, F. & Xia, K., 2022, In: Genes. 13, 8, 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular Mechanism of Action for Allosteric Modulators and Agonists in CC-chemokine Receptor 5 (CCR5)
Karlshøj, S., Amarandi, R. M., Larsen, Olav, Daugvilaite, V., Steen, A., Brvar, M., Pui, A., Frimurer, Thomas Michael, Ulven, Trond & Rosenkilde, Mette, 23 Dec 2016, In: Journal of Biological Chemistry. 291, 52, p. 26860-26874Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular Mechanisms and Genome-Wide Aspects of PPAR Subtype Specific Transactivation
Bugge, A. S. & Mandrup, S., 2010, In: PPAR Research. 2010Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular Mechanisms of Glucose-Stimulated GLP-1 Secretion From Perfused Rat Small Intestine
Kuhre, Rune Ehrenreich, Frost, C. R., Svendsen, B. & Holst, Jens Juul, Feb 2015, In: Diabetes. 64, 2, p. 370-382 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular adaptations in human subcutaneous adipose tissue after ten weeks of endurance exercise training in healthy males
Riis, S., Christensen, B., Nellemann, B., Moller, A. R., Husted, Anna Sofie, Pedersen, S. B., Schwartz, Thue W., Jorgensen, J. O. L. & Jessen, N., 2019, In: Journal of Applied Physiology. 126, 3, p. 569-577Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular and in vivo phenotyping of missense variants of the human glucagon receptor
van der Velden, W. J. C., Lindquist, Peter, Madsen, Jakob Sture, Stassen, R. H. M. J., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Hauser, Alexander Sebastian & Rosenkilde, M. M., 2022, In: Journal of Biological Chemistry. 298, 2, 101413.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular characterization of a 40-kDa outer membrane protein, FomA, of Fusobacterium periodonticum and comparison with Fusobacterium nucleatum
Bolstad, A. I., Høgh, Birthe & Jensen, H. B., Oct 1995, In: Oral Microbiology and Immunology. 10, 5, p. 257-64 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular characterization of irinotecan (SN-38) resistant human breast cancer cell lines
Jandu, H., Aluzaité, K., Fogh, L., Thrane, S. W., Noer, J. B., Proszek, J., Nguyen Do, K., Hansen, S. N., Damsgaard-Hansen, B., Nielsen, S. L., Stougaard, M., Knudsen, B. R., Moreira, J., Hamerlik, P., Gajjar, M., Smid, M., Martens, J., Foekens, J., Pommier, Y., Brünner, N. & 2 others, , 22 Jan 2016, In: B M C Cancer. 16, 13 p., 34.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular characterization of oxysterol binding to the Epstein-Barr virus-induced gene 2 (GPR183)
Benned-Jensen, T., Norn, C., Laurent, S., Madsen, C. M., Larsen, H. M., Arfelt, K. N., Wolf, R. M., Frimurer, Thomas Michael, Sailer, A. W. & Rosenkilde, Mette, 12 Oct 2012, In: The Journal of Biological Chemistry. 287, 42, p. 35470-83 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular consequences of peripheral Influenza A infection on cell populations in the murine hypothalamus
Lemcke, René, Jensen, Christine Egebjerg, Pagh-Berendtsen, Nicolai, Egerod, Kristoffer Lihme, Thomsen, Allan Randrup, Pers, Tune H, Christensen, Jan Pravsgaard & Kornum, Birgitte Rahbek, 2023, In: eLife. 12, 28 p., RP87515.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular constituents of the extracellular matrix in rat liver mounting a hepatic progenitor cell response for tissue repair
Vestentoft, P. S., Jelnes, P., Andersen, Jesper Bøje, Tran, T. A. T., Jørgensen, T., Rasmussen, M., Lange, Jette Bornholdt, Grøvdal, L. M., Jensen, C. H., Vogel, Lotte, Thorgeirsson, S. S. & Bisgaard, Hanne Cathrine, 2013, In: Fibrogenesis & Tissue Repair. 6, 1, 15 p., 21.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular dynamics-based identification of binding pathways and two distinct high-affinity sites for succinate in succinate receptor 1/GPR91
Iliyaz, Aslihan Shenol, Lückmann, Michael, Trauelsen, Mette, Lambrughi, M., Tiberti, M., Papaleo, E., Frimurer, Thomas Michael & Schwartz, Thue W., 2024, In: Molecular Cell. 84, 5, p. 955-966.e4 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular dynamics-guided discovery of an ago-allosteric modulator for GPR40/FFAR1
Lückmann, Michael, Trauelsen, Mette, Bentsen, M. A., Nissen, T. A. D., Martins, J., Fallah, Z., Nygaard, M. M., Papaleo, E., Lindorff-Larsen, Kresten, Schwartz, Thue W. & Frimurer, Thomas Michael, 2 Apr 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 14, p. 7123-7128Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular genetic overlap between migraine and major depressive disorder
Yang, Y., Zhao, H., Boomsma, D. I., Ligthart, L., Belin, A. C., Smith, G. D., Esko, T., Freilinger, T. M., Hansen, T. F., Ikram, M. A., Kallela, M., Kubisch, C., Paraskevi, C., Strachan, D. P., Wessman, M., Gormley, P., Anttila, V., Winsvold, B. S., Palta, P., Esko, T. & 30 others, , 2018, In: European Journal of Human Genetics. 26, 8, p. 1202-1216 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular mechanism of action of non-peptide ligands for peptide receptors
Schwartz, Thue W., Gether, Ulrik, Schambye, H. T. & Hjorth, Siv Annegrethe, Oct 1995, In: Current Pharmaceutical Design. 1, 3, p. 325-342 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular mechanism of ligand binding pathways and activation of the succinate receptor
Iliyaz, Aslihan Shenol, Lückmann, Michael, Trauelsen, Mette, Frimurer, Thomas Michael & Schwartz, Thue W., 2021, In: European Biophysics Journal. 50, Suppl. 1, p. 160 1 p., P-234.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Molecular mechanisms of lipoapoptosis and metformin protection in GLP-1 secreting cells
Kappe, C., Holst, Jens Juul, Zhang, Q. & Sjöholm, A., 12 Oct 2012, In: Biochemical and Biophysical Research Communications. 427, 1, p. 91-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular properties of adult mouse gastric and intestinal epithelial progenitors in their niches
Giannakis, M., Stappenbeck, T. S., Mills, J. C., Leip, D. G., Lovett, M., Clifton, S. W., Ippolito, J. E., Glasscock, J. I., Arumugam, Mani, Brent, M. R. & Gordon, J. I., 2006, In: Journal of Biological Chemistry. 281, 16, p. 11292-300 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular-scale simulation of electroluminescence in a multilayer white organic light-emitting diode
Mesta, M., Carvelli, M., de Vries, R. J., van Eersel, H., van der Holst, J. J. M., Schober, M., Furno, M., Lüssem, B., Leo, K., Loebl, P., Coehoorn, R., Bobbert, P. A. & Holst, Jens Juul, Jul 2013, In: Nature Materials. 12, 7, p. 652-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molekylaer patogenese ved monogen og polygen fedme
Larsen, P. J., Echwald, S. M., Sørensen, Thorkild I.A. & Pedersen, Oluf Borbye, 2006, In: Ugeskrift for Laeger. 168, 2, p. 152-5 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Monitoring kidney function in type 2 diabetic patients with incipient and overt diabetic nephropathy
Rossing, Peter, Rossing, K., Gaede, P., Pedersen, Oluf Borbye & Parving, H., 2006, In: Diabetes Care. 29, 5, p. 1024-30 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mono- and co-activation of the GIP and GLP-1 receptors inhibits bone resorption
Bergmann, N. C., Lund, A., Heimburger, S. M., Gasbjerg, Lærke Smidt, Jørgensen, Niklas Rye, Jessen, L., Hartmann, Bolette, Holst, Jens Juul, Christensen, Mikkel Bring, Vilsbøll, Tina & Knop, Filip Krag, 2018, In: Diabetologia. 61, S.1, p. S348-S348 717.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Monoamines' role in islet cell function and type 2 diabetes risk
Roberts, F. L., Cataldo, L. R. & Fex, M., 2023, In: Trends in Molecular Medicine. 29, 12, p. 1045-1058 14 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Monocarboxylate transporters facilitate succinate uptake into brown adipocytes
Reddy, A., Winther, Sally, Tran, N., Xiao, H., Jakob, J., Garrity, R., Smith, A., Ordonez, M., Laznik-Bogoslavski, D., Rothstein, J. D., Mills, E. L. & Chouchani, E. T., 2024, In: Nature Metabolism. 6, 3, p. 567–577 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Monogenic diabetes variants in Emirati women with gestational diabetes are associated with risk of non-autoimmune diabetes within 5 years after pregnancy
Daggag, H., Gjesing, A. P., Mohammad, A., Ängquist, Lars, Shobi, B., Antony, S., Haj, D., Al Tikriti, A., Buckley, A., Hansen, Torben & Barakat, M. T., 2022, In: Metabolism open. 16, 7 p., 100213.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Morbidity, Mortality And Lung Function In 14 Extracellular Superoxide Dismutase R213g Homozygotes Among 95,873 Individuals From The General Population
Kobylecki, C. J., Afzal, Shoaib & Nordestgaard, Børge, 2016, In: American Journal of Respiratory and Critical Care Medicine. 193, 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Morbidity, including fatal morbidity, throughout life in men entering adult life as obese
Zimmermann, E., Holst, C. & Sørensen, Thorkild I.A., 2011, In: P L o S One. 6, 4, p. e18546Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mosaic chromosomal alterations in blood across ancestries using whole-genome sequencing
Jakubek, Y. A., Zhou, Y., Stilp, A., Bacon, J., Wong, J. W., Ozcan, Z., Arnett, D., Barnes, K., Bis, J. C., Boerwinkle, E., Brody, J. A., Carson, A. P., Chasman, D. I., Chen, J., Cho, M., Conomos, M. P., Cox, N., Doyle, M. F., Fornage, M., Guo, X. & 31 others, , 2023, In: Nature Genetics. 55, 11, p. 1912-1919 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Motivations for data sharing—views of research participants from four European countries: A DIRECT study
Shah, N., Coathup, V., Teare, H., Forgie, I., Giordano, G. N., Hansen, T. H., Groeneveld, L., Hudson, M., Pearson, E., Ruetten, H. & Kaye, J., 2019, In: European Journal of Human Genetics. 27, p. 721-729Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MuRF1 activity is present in cardiac mitochondria and regulates reactive oxygen species production in vivo
Mattox, T. A., Young, M. E., Rubel, C. E., Spaniel, C., Rodríguez, J. E., Grevengoed, Trisha Jean, Gautel, M., Xu, Z., Anderson, E. J. & Willis, M. S., Jun 2014, In: Journal of Bioenergetics and Biomembranes. 46, 3, p. 173-87 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mucosal Metabolomic Profiling and Pathway Analysis Reveal the Metabolic Signature of Ulcerative Colitis
Diab, J., Hansen, T., Goll, R., Stenlund, H., Jensen, E., Moritz, Thomas, Florholmen, J. & Forsdahl, G., 2019, In: Metabolites. 9, 12, 15 p., 291.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multi-ancestry Genome-wide Meta-analysis Accounting for Gene-education Interactions in Up to 227,850 Individuals Identifies Several Novel Lipid Loci
Sung, Y. J., Schwander, K. L., Bentley, A. R., de Vries, P. S., Kilpeläinen, Tuomas O., Noordam, R., Musani, S. K., Aschard, H., de las Fuentes, L. & CHARGE Gene-Lifestyle Interactions, C. G. I., 2019, In: Genetic Epidemiology. 43, 7, p. 912-912 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation
Mahajan, A., Spracklen, C. N., Zhang, W., Ng, M. C. Y., Petty, L. E., Kitajima, H., Yu, G. Z., Rüeger, S., Speidel, L., Kim, Y. J., Horikoshi, M., Mercader, J. M., Taliun, D., Moon, S., Kwak, S-H., Robertson, N. R., Rayner, N. W., Loh, M., Kim, B-J., Chiou, J. & 31 others, , 2022, In: Nature Genetics. 54, 5, p. 560-572 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Multi-ancestry genome-wide association study accounting for gene-psychosocial factor interactions identifies novel loci for blood pressure traits
LifeLines Cohort Study, L. C. S., 2021, In: Human Genetics and Genomics Advances. 2, 1, 12 p., 100013.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis
Paternoster, L., Standl, M., Waage, J., Baurecht, H., Hotze, M., Strachan, D. P., Curtin, J. A., Bønnelykke, K., Tian, C., Takahashi, A., Esparza-Gordillo, J., Alves, A. C., Thyssen, J. P., den Dekker, H. T., Ferreira, M. A., Altmaier, E., Sleiman, P. M. A., Xiao, F. L., Gonzalez, J. R., Marenholz, I. & 31 others, , Dec 2015, In: Nature Genetics. 47, 12, p. 1449-56 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multi-ancestry genome-wide association study of major depression aids locus discovery, fine mapping, gene prioritization and causal inference
Meng, X., Navoly, G., Giannakopoulou, O., Levey, D. F., Koller, D., Pathak, G. A., Koen, N., Lin, K., Adams, M. J., Rentería, M. E., Feng, Y., Gaziano, J. M., Stein, D. J., Zar, H. J., Campbell, M. L., van Heel, D. A., Trivedi, B., Finer, S., McQuillin, A., Bass, N. & 58 others, , 2024, In: Nature Genetics. 56, 2, p. 222–233Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure
Wang, H., Noordam, R., Cade, B. E., Schwander, K., Winkler, T. W., Lee, J., Sung, Y. J., Bentley, A. R., Manning, A. K., Aschard, H., Kilpeläinen, T. O., Ilkov, M., Brown, M. R., Horimoto, A. R., Richard, M., Bartz, T. M., Vojinovic, D., Lim, E., Nierenberg, J. L., Liu, Y. & 105 others, , 2021, In: Molecular Psychiatry. 26, p. 6293-6304Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids
Bentley, A. R., Sung, Y. J., Brown, M. R., Winkler, T. W., Kraja, A. T., Ntalla, I., Schwander, K., Chasman, D. I., Lim, E., Deng, X., Guo, X., Liu, J., Lu, Y., Cheng, C-Y., Sim, X., Vojinovic, D., Huffman, J. E., Musani, S. K., Li, C., Feitosa, M. F. & 32 others, , Apr 2019, In: Nature Genetics. 51, 4, p. 636-648 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications
VA Million Veteran Program, V. M. V. P., 2023, medRxiv, 39 p.Research output: Working paper › Preprint › Research
- Published
Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration
Noordam, R., Bos, M. M., Wang, H., Winkler, T. W., Bentley, A. R., Kilpeläinen, T. O., de Vries, P. S., Sung, Y. J., Schwander, K., Cade, B. E., Manning, A., Aschard, H., Brown, M. R., Chen, H., Franceschini, N., Musani, S. K., Richard, M., Vojinovic, D., Aslibekyan, S., Bartz, T. M. & 128 others, , 2019, In: Nature Communications. 10, 1, 13 p., 5121.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity
Kilpeläinen, T. O., Bentley, A. R., Noordam, R., Sung, Y. J., Schwander, K., Winkler, T. W., Jakupović, H., Chasman, D. I., Manning, A., Ntalla, I., Aschard, H., Brown, M. R., de las Fuentes, L., Franceschini, N., Guo, X., Vojinovic, D., Aslibekyan, S., Feitosa, M. F., Kho, M., Musani, S. K. & 32 others, , 2019, In: Nature Communications. 10, 11 p., 376.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multi-component prime-boost Chlamydia trachomatis vaccination regimes induce antibody and T cell responses and accelerate clearance of infection in a non-human primate model
Lorenzen, E., Contreras, V., Olsen, A. W., Andersen, P., Desjardins, D., Rosenkrands, I., Juel, H. B., Delache, B., Langlois, S., Delaugerre, C., Joubert, C., Dereuddre-Bosquet, N., Bébéar, C., De Barbeyrac, B., Touati, A., McKay, P. F., Shattock, R. J., Le Grand, R., Follmann, F. & Dietrich, J., 2022, In: Frontiers in Immunology. 13, 13 p., 1057375.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multi-omics characterization of a diet-induced obese model of non-alcoholic steatohepatitis
Ægidius, H. M., Veidal, S. S., Feigh, M., Hallenborg, P., Puglia, M., Pers, Tune H, Vrang, N., Jelsing, J., Kornum, Birgitte Rahbek, Blagoev, B. & Rigbolt, K. T. G., 2020, In: Scientific Reports. 10, 1, 12 p., 1148.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multi-technique approach for qualitative and quantitative characterization of furazidin degradation kinetics under alkaline conditions
Bērziņš, Kārlis, Kons, A., Grante, I., Dzabijeva, D., Nakurte, I. & Actiņš, A., 2016, In: Journal of Pharmaceutical and Biomedical Analysis.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications
Sterenborg, R. B. T. M., Steinbrenner, I., Li, Y., Bujnis, M. N., Naito, T., Marouli, E., Galesloot, T. E., Babajide, O., Andreasen, L., Astrup, A., Åsvold, B. O., Bandinelli, S., Beekman, M., Beilby, J. P., Bork-Jensen, J., Boutin, T., Brody, J. A., Brown, S. J., Brumpton, B., Campbell, P. J. & 121 others, , 2024, In: Nature Communications. 15, 1, 18 p., 888.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MultiPep: a hierarchical deep learning approach for multi-label classification of peptide bioactivities
Grønning, Alexander GB, Kacprowski, T. & Schéele, Camilla Charlotte Nielsen, 2021, In: Biology Methods and Protocols. 6, 1, 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multiancestry Genome-Wide Association Study of Aortic Stenosis Identifies Multiple Novel Loci in the Million Veteran Program
Small, A. M., Peloso, G. M., Linefsky, J., Aragam, J., Galloway, A., Tanukonda, V., Wang, L. C., Yu, Z., Sunitha Selvaraj, M., Farber-Eger, E. H., Baker, M. T., Setia-Verma, S., Lee, S. S. K., Preuss, M., Ritchie, M. D., Damrauer, S. M., Rader, D. J., Wells, Q. S., Loos, R., Lubitz, S. A. & 5 others, , 2023, In: Circulation. 147, 12, p. 942-955 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions
de Vries, P. S., Brown, M. R., Bentley, A. R., Sung, Y. J., Winkler, T. W., Ntalla, I., Schwander, K., Kraja, A. T., Guo, X., Franceschini, N., Cheng, C-Y., Sim, X., Vojinovic, D., Huffman, J. E., Musani, S. K., Li, C., Feitosa, M. F., Richard, M. A., Noordam, R., Aschard, H. & 32 others, , 2019, In: American Journal of Epidemiology. 188, 6, p. 1033-1054Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multidisciplinary care of obese children and adolescents for one year reduces ectopic fat content in liver and skeletal muscle
Fonvig, C. E., Chabanova, E., Ohrt, J. D., Nielsen, L. A., Pedersen, Oluf Borbye, Hansen, Torben, Thomsen, Henrik S. & Holm, Jens-Christian, 2015, In: B M C Pediatrics. 15, p. 1-9 9 p., 196.Research output: Contribution to journal › Journal article › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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The isoenzyme pattern of LDH does not play a physiological role; except perhaps during fast transitions in energy metabolism
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