- Published
Structure-Activity Investigations and Optimisations of Non-metabolite Agonists for the Succinate Receptor 1
Ulven, Elisabeth Rexen, Trauelsen, Mette, Brvar, M., Lückmann, Michael, Bielefeldt, L. Ø., Jensen, L. K. I., Schwartz, Thue W. & Frimurer, Thomas Michael, 2018, In: Scientific Reports. 8, 1, p. 1-18 10010.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structure-Activity Relationships and Identification of Optmized CC-Chemokine Receptor CCR1, 5, and 8 Metal-Ion Chelators
Chalikiopoulos, A., Thiele, S., Malmgaard-Clausen, M., Rydberg, P., Isberg, V., Ulven, Trond, Frimurer, Thomas Michael, Rosenkilde, Mette & Gloriam, David E., 25 Nov 2013, In: Journal of Chemical Information and Modeling. 53, 11, p. 2863-73 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structure-Activity Studies of 3,9-Diazaspiro[5.5]undecane-Based ?-Aminobutyric Acid Type A Receptor Antagonists with Immunomodulatory Effect
Bavo, Francesco, De-Jong, H., Petersen, Jonas Odgaard, Falk-Petersen, C. B., Löffler, R., Sparrow, E., Rostrup, F., Eliasen, Jannik Nicklas, Wilhelmsen, K. S., Barslund, K., Bundgaard, C., Nielsen, Birgitte, Kristiansen, Uffe, Wellendorph, Petrine, Bogdanov, Y. & Frølund, Bente, 2021, In: Journal of Medicinal Chemistry. 64, 24, p. 17795-17812Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structure-based discovery of novel US28 small molecule ligands with different modes of action
Lückmann, Michael, Amarandi, R., Papargyri, N., Jakobsen, M. H., Ulven, Elisabeth Rexen, Jensen, Lars Juhl, Pui, A., Schwartz, Thue W., Rosenkilde, Mette & Frimurer, Thomas Michael, 2017, In: Chemical Biology & Drug Design. 89, 3, p. 289–296Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structured exercise alters the gut microbiota in humans with overweight and obesity - A randomized controlled trial
Kern, T., Blond, Martin Bæk, Hansen, T. H., Rosenkilde, M., Quist, Jonas Salling, Gram, A. S., Ekstrøm, Claus Thorn, Hansen, Torben & Stallknecht, Bente Merete, 2020, In: International Journal of Obesity. 44, p. 125-135 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structured supervised exercise training or motivational counselling during pregnancy on physical activity level and health of mother and offspring: FitMum study protocol
Roland, Caroline Borup, Knudsen, S. D. P., Alomairah, S. A., Jessen, Anne Dsane, Bendix, J., Clausen, Tine Dalsgaard, Mølsted, Stig, Jensen, Andreas Kryger, Teilmann, Grete Katrine, Jespersen, Astrid Pernille, Larsen, J. E., van Hall, Gerrit, Andersen, E., Barrès, Romain, Mortensen, Ole Hartvig, Maindal, H. T., Tarnow, L., Løkkegaard, Ellen Christine Leth & Stallknecht, Bente Merete, 19 Mar 2021, In: BMJ Open. 11, 3, 11 p., e043671.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies based on the Danish Adoption Register: schizophrenia, BMI, smoking, and mortality in perspective
Petersen, L. & Sørensen, Thorkild I.A., 2011, In: Scandinavian Journal of Public Health. 39, 7 Suppl, p. 191-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies in Rats of Combined Muscle and Liver Perfusion and of Muscle Extract Indicate That Contractions Release a Muscle Hormone Directly Enhancing Hepatic Glycogenolysis
Han, X. X., Holst, Jens Juul & Galbo, Henrik, 2022, In: Journal of Personalized Medicine. 12, 5, 12 p., 837.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies of CTNNBL1 and FDFT1 variants and measures of obesity: analyses of quantitative traits and case-control studies in 18,014 Danes
Andreasen, C. H., Mogensen, M. S., Borch-Johnsen, K., Sandbaek, A., Lauritzen, T., Almind, K., Hansen, L., Jørgensen, T., Pedersen, Oluf Borbye & Hansen, Torben, 2009, In: BMC Medical Genetics. 10, 1, p. 17Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies of a genetic variant in HK1 in relation to quantitative metabolic traits and to the prevalence of type 2 diabetes
Gjesing, A. P., Nielsen, A. A., Brandslund, I., Christensen, C., Sandbæk, A., Jørgensen, T., Witte, D., Bonnefond, A., Froguel, P., Hansen, Torben & Pedersen, Oluf Borbye, 1 Jan 2011, In: B M C Medical Genetics. 12, p. 99 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies of association between LPIN1 variants and common metabolic phenotypes among 17,538 Danes
Burgdorf, K. S., Sandholt, C. H., Sparsø, T., Andersen, G., Witte, D. R., Jørgensen, T., Sandbaek, A., Lauritzen, T., Sørensen, Thorkild I.A., Madsbad, Sten, Hansen, Torben & Pedersen, Oluf Borbye, 1 Jul 2010, In: European Journal of Endocrinology. 163, 1, p. 81-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies of association of AGPAT6 variants with type 2 diabetes and related metabolic phenotypes in 12,068 Danes
Snogdal, L. S., Grarup, Niels, Banasik, Karina, Wod, M., Jørgensen, T., Witte, D. R., Lauritzen, T., Nielsen, A. A., Brandslund, I., Christensen, C., Pedersen, Oluf Borbye, Yderstræde, K. B., Beck-Nielsen, H., Henriksen, J. E., Hansen, Torben & Højlund, K., 25 Oct 2013, In: BMC Medical Genetics. 14, 1, p. 113Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies of association of the CASQ1 rs2275703 polymorphism in relation to type 2 diabetes and related quantitative metabolic traits among 7,088 Danish whites
Sparsø, T., Hussain, M. S., Borch-Johnsen, K., Jørgensen, T., Madsbad, Sten, Hansen, Torben, Pedersen, Oluf Borbye & Andersen, G., 2007, In: Molecular Genetics and Metabolism. 92, 3, p. 278-282 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies of gene expression and activity of hexokinase, phosphofructokinase and glycogen synthase in human skeletal muscle in states of altered insulin-stimulated glucose metabolism
drb459, drb459, Feb 1999, In: Danish Medical Bulletin (Print). 46, 1, p. 13-34 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies of insulin resistance in congenital generalized lipodystrophy
Søvik, O., drb459, drb459, Trygstad, O. & Pedersen, Oluf Borbye, Jun 1996, In: Acta Paediatrica. Supplement. 413, p. 29-37 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies of metabolic phenotypic correlates of 15 obesity associated gene variants
Sandholt, C. H., Vestmar, M. A., Bille, D. S., Borglykke, A., Almind, K., Hansen, L., Sandbæk, A., Lauritzen, T., Witte, D., Jørgensen, T., Pedersen, Oluf Borbye & Hansen, Torben, 1 Jan 2011, In: P L o S One. 6, 9, p. e23531 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies of relationships between variation of the human G protein-coupled receptor 40 Gene and Type 2 diabetes and insulin release
Hamid, Y. H., Vissing, H., Holst, Birgitte, Urhammer, S. A., Pyke, C., Hansen, S. K., Glümer, C., Borch-Johnsen, K., Jørgensen, T., Schwartz, Thue W., Pedersen, O. & Hansen, Torben, 2005, In: Diabetic Medicine. 22, 1, p. 74-80 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies of the Ala/Val98 polymorphism of the hepatocyte nuclear factor-1alpha gene and the relationship to beta-cell function during an OGTT in glucose-tolerant women with and without previous gestational diabetes mellitus
Lauenborg, J., Damm, Peter, Ek, J., Glümer, C., Jørgensen, Tina, Borch-Johnsen, K., Vestergaard, H., Hornnes, P., Pedersen, Oluf Borbye & Hansen, Torben, Dec 2004, In: Diabetic Medicine. 21, 12, p. 1310-5 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies of the Association of Arg72Pro of Tumor Suppressor Protein p53 with Type 2 Diabetes in a Combined Analysis of 55,521 Europeans
Burgdorf, K. S., Grarup, Niels, Justesen, Johanne Marie, Harder, M. N., Witte, D. R., Jørgensen, T., Sandbæk, A., Lauritzen, T., Madsbad, Sten, Hansen, Torben, DIAGRAM Consortium, D. C. & Pedersen, Oluf Borbye, 2011, In: P L o S One. 6, 1, p. e15813 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies of the associations between functional beta2-adrenergic receptor variants and obesity, hypertension and type 2 diabetes in 7,808 white subjects
Gjesing, A. P., Andersen, G., Burgdorf, Kristoffer Sølvsten, Borch-Johnsen, K., Jørgensen, T., Hansen, Torben & Pedersen, Oluf Borbye, Mar 2007, In: Diabetologia. 50, 3, p. 563-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies of the common DIO2 Thr92Ala polymorphism and metabolic phenotypes in 7342 Danish white subjects
Grarup, Niels, Lepola, Mette Andersen, Andreasen, C. H., Albrechtsen, Anders, Borch-Johnsen, K., Jørgensen, T., Auwerx, J., Schmitz, O., Hansen, Torben & Pedersen, Oluf Borbye, 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 1, p. 363-6 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies of the variability of the genes encoding the insulin-like growth factor I receptor and its ligand in relation to type 2 diabetes mellitus
Rasmussen, S. K., Lautier, C., Hansen, L., Echwald, S. M., Hansen, Torben, Ekstrøm, Claus Thorn, Urhammer, Søren Asger, Borch-Johnsen, K., Grigorescu, F., Smith, R. J. & Pedersen, Oluf Borbye, 1 Dec 2000, In: Journal of Clinical Endocrinology and Metabolism. 85, 4, p. 1606-1610 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies of variability in the PTEN gene among Danish caucasian patients with Type II diabetes mellitus
Hansen, L., Jensen, J. N., Ekstrøm, Claus Thorn, drb459, drb459, Hansen, Teis Schjals, Pedersen, Oluf Borbye & drb459, drb459, Feb 2001, In: Diabetologia. 44, 2, p. 237-240 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies of variations of the cyclin-dependent kinase inhibitor 1C and the cyclin-dependent kinase 4 genes in relation to type 2 diabetes mellitus and related quantitative traits
Nielsen, E. D., Hansen, L., Stissing, T., Yanagisawa, K., Borch-Johnsen, K., Poulsen, P., Vaag, Allan, Hansen, Torben & Pedersen, Oluf Borbye, 2005, In: Journal of Molecular Medicine. 83, 5, p. 353-61 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Subclinical Hypothyroidism in Danish Lean and Obese Children and Adolescents
Dahl, M., Ohrt, J. D., Fonvig, C. E., Kloppenborg, J. T., Pedersen, Oluf Borbye, Hansen, Torben & Holm, Jens-Christian, 1 Mar 2017, In: JCRPE Journal of Clinical Research in Pediatric Endocrinology. 9, 1, p. 8-16 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Subcutaneous GIP and GLP-2 inhibit nightly bone resorption in postmenopausal women: A preliminary study
Skov-Jeppesen, Kirsa, Veedfald, Simon, Madsbad, Sten, Holst, Jens Juul, Rosenkilde, Mette & Hartmann, Bolette, 2021, In: Bone. 152, 7 p., 116065.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Subcutaneous injection of glucagon-like insulintropic peptide reduces postprandial glycemia in non-insulin dependent diabetes
Gutniak, M. K., Linde, B., Holst, Jens Juul & Efendic, S., 1994, In: Diabetes Care. 17, p. 1039-1044Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Subjective evaluation of psychosocial well-being in children and youths with overweight or obesity: the impact of multidisciplinary obesity treatment
Fonvig, Cilius Esmann, Hamann, S. A., Nielsen, T. R. H., Johansen, M. Ø., Grønbæk, H. N., Mollerup, P. M. & Holm, Jens-Christian, Dec 2017, In: Quality of Life Research. 26, 12, p. 3279-3288 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Suboptimal Weight Loss 13 Years After Roux-en-Y Gastric Bypass Is Associated with Blunted Appetite Response
Nymo, S., Lundanes, J., Eriksen, K., Aukan, M., Rehfeld, Jens Frederik, Holst, Jens Juul, Johnsen, G., Græslie, H., Kulseng, B., Sandvik, J. & Martins, C., 2024, In: Obesity Surgery. 34, 2, p. 592-601Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Substance P and Neurokinin A are Codistributed and Colocalized in the Porcine Gastrointestinal Tract
Schmidt, P., Poulsen, S. S., Rasmussen, T. N., Bersani, M. & Holst, Jens Juul, 1991, In: Peptides. 12, p. 963-973Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Substance P and neurokinin A are codistributed and colocalized in the porcine gastrointestinal tract
Poulsen, Steen Seier, Bersani, M., Holst, Jens Juul, Schmidt, P. & N. Rasmussen, T., 1991, In: Peptides. 12, 5, p. 963-73 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Substituted thiazoleacetic acids as CRTH2 receptor ligands
Ulven, Trond, Frimurer, Thomas Michael, Rist, Ø., Kostenis, E., Högberg, T., Receveur, J. & Grimstrup, M., 2005, Patent No. WO 2005/116001 A1Research output: Patent
- Published
Substrate metabolism, hormone and cytokine levels and adipose tissue signalling in individuals with type 1 diabetes after insulin withdrawal and subsequent insulin therapy to model the initiating steps of ketoacidosis
Voss, T. S., Vendelbo, M. H., Kampmann, U., Pedersen, S. B., Nielsen, Thomas Svava, Johannsen, M., Svart, M. V., Jessen, N. & Møller, N., 2019, In: Diabetologia. 62, 3, p. 494-503Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Succesfuld behandling af KCNJ11-neonatal diabetes uden insulin
Gade-Rasmussen, B., Madsbad, Sten, Svane, M. S., Martinussen, C. & Hansen, Torben, 2018, In: Ugeskrift for Laeger. 180, 46, 2 p., V08180547.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Successful treatment of psoriasis with adalimumab induced no changes in the gut microbiota
Todberg, T., Egeberg, Alexander, Zachariae, Claus, Sørensen, N., Pedersen, Oluf Borbye & Skov, Lone, 2022, In: Journal of the European Academy of Dermatology and Venereology. 36, 6, p. e464-e467 4 p.Research output: Contribution to journal › Comment/debate › Research
- Published
Successful weight loss maintenance includes long-term increased meal responses of GLP-1 and PYY3-36
Iepsen, E. W., Lundgren, J., Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, Jun 2016, In: European Journal of Endocrinology. 174, 6, p. 775-784 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sucrose synthase activity is not required for cellulose biosynthesis in Arabidopsis
Wang, W., Viljamaa, S., Hodek, O., Moritz, Thomas & Niittylä, T., 2022, In: Plant Journal. 110, 5, p. 1493-1497Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sugar- or artificially-sweetened beverage consumption, physical activity, and risk of cardiovascular disease in US adults
Pacheco, L. S., Tobias, D. K., Li, Y., Bhupathiraju, S. N., Willett, W. C., Ludwig, D. S., Ebbeling, C. B., Haslam, D. E., Drouin-Chartier, J., Hu, F. B. & Guasch Ferre, Marta, 2023, medRxiv, 29 p.Research output: Working paper › Preprint › Research
- Published
Sugar-sweetened or artificially-sweetened beverage consumption, physical activity, and risk of cardiovascular disease in adults: a prospective cohort study
Pacheco, L. S., Tobias, D. K., Li, Y., Bhupathiraju, S. N., Willett, W. C., Ludwig, D. S., Ebbeling, C. B., Haslam, D. E., Drouin-Chartier, J. P., Hu, F. B. & Guasch Ferre, Marta, 2024, In: American Journal of Clinical Nutrition. 119, 3, p. 669-681 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sulfonylurea therapy improves glucose disposal without changing skeletal muscle GLUT4 levels in noninsulin-dependent diabetes mellitus subjects: a longitudinal study
drb459, drb459, Weinreb, J. E., Rosen, A. S., Bjørbaek, C., Hansen, L., Pedersen, Oluf Borbye & Kahn, B. B., Jan 1995, In: The Journal of clinical endocrinology and metabolism. 80, 1, p. 270-5 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Superficial fungal infections and patients with hidradenitis suppurativa: a study under the Danish Blood Donor Study
Lindso Andersen, P., Andersen, Rune Kjærsgaard, Jemec, Gregor, Ullum, H., Erikstrup, C., Nielsen, K. R., Bruun, M. T., Hjalgrim, Henrik, Sørensen, E., Burgdorf, K. S., Dinh, K. M., Banasik, Karina, Hansen, T., Saunte, Ditte Marie & Pedersen, Oluf Borbye, 2021, In: Clinical and Experimental Dermatology. 46, 3, p. 571-573 3 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Supplementation of Diet With Galacto-oligosaccharides Increases Bifidobacteria, but Not Insulin Sensitivity, in Obese Prediabetic Individuals
Canfora, E. E., van der Beek, C. M., Hermes, G. D. A., Goossens, G. H., Jocken, J. W. E., Holst, Jens Juul, van Eijk, H. M., Venema, K., Smidt, H., Zoetendal, E. G., Dejong, C. H. C., Lenaerts, K. & Blaak, E. E., Jul 2017, In: Gastroenterology. 153, 1, p. 87-97.e3Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Supplementation of cyanidin-3-O-β-glucoside-rich haskap (Lonicera caerulea L.) berry extract attenuates hepatic lipid dysregulation in diet-induced obese mice
Biswas, Dipsikha, De Silva, A. B. K. H., Mercer, A., Sarkar, S., Kienesberger, P., Langille, M., Rupasinghe, H. P. V. & Pulinilkunnil, T., 2023, In: Journal of Functional Foods. 108, 11 p., 105635.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Surgically Induced Interpregnancy Weight Loss and Prevalence of Overweight and Obesity in Offspring
Willmer, M., Berglind, D., Sørensen, Thorkild I.A., Näslund, E., Tynelius, P. & Rasmussen, F., 2013, In: P L o S One. 8, 12, p. 1-7 7 p., e82247.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sustained AS160 and TBC1D1 phosphorylations in human skeletal muscle 30 minutes after a single bout of exercise
Vendelbo, M. H., Møller, A. B., Treebak, Jonas Thue, Gormsen, L. C., Goodyear, L. J., Wojtaszewski, Jørgen F P, Jorgensen, J. O. L., Møller, N. & Jessen, N., 2014, In: Journal of Applied Physiology. 117, 3, p. 289-296 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sustained Improvements in Glucose Metabolism Late After Roux-En-Y Gastric Bypass Surgery in Patients with and Without Preoperative Diabetes
Jørgensen, N. B., Bojsen-Møller, K. N., Dirksen, C., Martinussen, C., Svane, M. S., Kristiansen, V. B., Holst, Jens Juul & Madsbad, Sten, 2019, In: Scientific Reports. 9, 1, 10 p., 15154.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sustained glucagon-like peptide-2 infusion is required for intestinal adaptation, and cessation reverses increased cellularity in rats with intestinal failure
Koopmann, M. C., Chen, X., Holst, Jens Juul & Ney, D. M., 1 Dec 2010, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 299, 6, p. G1222-30 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sustained influence of metformin therapy on circulating glucagon-like peptide-1 levels in individuals with and without type 2 diabetes
DIRECT consortium group, D. C. G., 2017, In: Diabetes, Obesity and Metabolism. 19, 3, p. 356-363 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sustained inhibition of NPY/AgRP neuronal activity by FGF1
Hwang, E., Scarlett, J. M., Baquero, A. F., Bennett, C. M., Dong, Y., Chau, D., Brown, Jenny, Mercer, A. J., Meek, T. H., Grove, K. L., Phan, B. A. N., Morton, G. J., Williams, K. W. & Schwartz, M. W., 2022, In: JCI insight. 7, 17, 11 p., e160891.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Svær overvægt hos børn og unge
Kloppenborg, J. T. & Holm, Jens-Christian, 31 Oct 2016, In: Ugeskrift for Laeger. 178, 22, p. 2089-2092 4 p., V06160432.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Svær overvægt og ugunstig livsstil følges af øget risiko for type 2-diabetes uanset genetisk disposition
Jakupovic, Hermina & Schnurr, T. M., 5 Jun 2020, Best Practice Nordic.Research output: Other contribution › Net publication - Internet publication › Research
- Published
Sweet Taste Receptor Activation in the Gut Is of Limited Importance for Glucose-Stimulated GLP-1 and GIP Secretion
Saltiel, M. Y., Kuhre, Rune Ehrenreich, Christiansen, Charlotte Bayer, Eliasen, R., Conde-Frieboes, K. W., Rosenkilde, Mette & Holst, Jens Juul, 2017, In: Nutrients. 9, 4, 15 p., 418.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sympathoadrenal regulation of adrenal androstenedione release
Ehrhart-Bornstein, M., Bornstein, S. R., Behling, H. G., Holst, Jens Juul, Strohmayer, H. G., Rasmussen, T. N., Scherbaum, W. A. & Adler, G., 1994, In: Neuroendocrinology. 59, p. 406-412Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sympathoadrenal regulation of adrenocortical steroidogenesis
Ehrhart-Bornstein, M., Bornstein, S. R., Gonzalez-Hernandez, J., Holst, Jens Juul, Watermann, M. R. & Scherbaum, W. A., 1995, In: Endocrine Research. 21, p. 13-24Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synaptotagmin-7 as a positive regulator of glucose-induced glucagon-like peptide-1 secretion in mice
Gustavsson, N., Wang, Y., Kang, Y., Seah, T., Chua, S., Radda, G. K. & Han, W., Jul 2011, In: Diabetologia. 54, 7, p. 1824-30 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synaptotagmin-7 is a principal Ca2+ sensor for Ca2+ -induced glucagon exocytosis in pancreas
Gustavsson, N., Wei, S., Hoang, D. N., Lao, Y., Zhang, Q., Radda, G. K., Rorsman, P., Südhof, T. C. & Han, W., 15 Mar 2009, In: The Journal of Physiology. 587, Pt 6, p. 1169-78 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synaptotagmin-7 phosphorylation mediates GLP-1-dependent potentiation of insulin secretion from β-cells
Wu, B., Wei, S., Petersen, N., Ali, Y., Wang, X., Bacaj, T., Rorsman, P., Hong, W., Südhof, T. C. & Han, W., 11 Aug 2015, In: National Academy of Sciences. Proceedings. 112, 32, p. 9996-10001 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synergy and oxygen adaptation for development of next-generation probiotics
Khan, M. T., Dwibedi, C., Sundh, D., Pradhan, M., Kraft, J. D., Caesar, R., Tremaroli, V., Lorentzon, M. & Bäckhed, F., 2023, In: Nature. 620, p. 381-385Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synthetic G protein-coupled bile acid receptor agonists and bile acids act via basolateral receptors in ileal and colonic mucosa
Tough, I. R., Schwartz, Thue W. & Cox, H. M., 2020, In: Neurogastroenterology and Motility. 32, 12, 14 p., e13943.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Systematic review and consensus definitions for the Standardized Endpoints in Perioperative Medicine (StEP) initiative: cardiovascular outcomes
StEP COMPAC Group, S. C. G., 2021, In: British Journal of Anaesthesia. 126, 1, p. 56-66 11 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Systemic immunogenicity of para-Phenylenediamine and Diphenylcyclopropenone: two potent contact allergy-inducing haptens
Svalgaard, J. D., Særmark, C., Dall, M., Buschard, K., Johansen, Jeanne Duus & Engkilde, K., Jan 2014, In: Immunologic Research. 58, 1, p. 40-50 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Systems Genetics Experimental Design and Analyses to Detect Causal Variants and Gene Regulatory Networks for Childhood Obesity in Denmark and India
BioChild consortium, B. C., 2012.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
Systems signatures reveal unique remission-path of Type 2 diabetes following Roux-en-Y gastric bypass surgery
Li, Q-R., Wang, Z-M., Albrechtsen, N. J. W., Wang, D-D., Su, Z-D., Gao, X-F., Wu, Q-Q., Zhang, H-P., Zhu, L., Li, R-X., Jacobsen, S., Jørgensen, N. B., Dirksen, C., Bojsen-Møller, K. N., Petersen, J. S., Madsbad, S., Clausen, T. R., Diderichsen, B., Chen, L-N., Holst, J. J. & 2 others, , 2018, In: EBioMedicine. 28, p. 234-240 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
T cell epigenetic remodeling and accelerated epigenetic aging are linked to long-term immune alterations in childhood cancer survivors
Daniel, S., Nylander, V., Ingerslev, L. R., Zhong, L., Fabre, O., Clifford, B., Johnston, K., Cohn, R. J., Barrès, Romain & Simar, D., 2018, In: Clinical Epigenetics. 10, p. 1-13 138.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TBC1D4-S711 controls skeletal muscle insulin sensitization after exercise and contraction
Kjøbsted, Rasmus, Kristensen, Jonas Møller, Eskesen, N. O., Kido, K., Fjorder, Klara, Damgaard, D. F., Larsen, Jeppe Kjærgaard, Andersen, Nicoline Resen, Birk, Jesper Bratz, Gudiksen, Anders, Treebak, Jonas Thue, Schjerling, Peter, Pilegaard, Henriette & Wojtaszewski, Jørgen F P, 2023, In: Diabetes. 72, 7, p. 857-871 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TFAP2B -Dietary Protein and Glycemic Index Interactions and Weight Maintenance after Weight Loss in the DiOGenes Trial
Stocks, T., Ängquist, Lars, Hager, J., Charon, C., Holst, C., Martinez, J. A., Saris, W. H. M., Astrup, A., Sørensen, Thorkild I.A. & Larsen, L. H., 2013, In: Human Heredity. 75, 2-4, p. 213-219 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TFAP2B influences the effect of dietary fat on weight loss under energy restriction
Stocks, T., Angquist, L., Banasik, K., Harder, M. N., Taylor, M. A., Hager, J., Arner, P., Oppert, J-M., Martinez, J. A., Polak, J., Rousseau, F., Langin, D., Rössner, S., Holst, C., Macdonald, I. A., Kamatani, Y., Pfeiffer, A. F. H., Kunesova, M., Saris, W. H. M., Hansen, T. & 3 others, , 2012, In: P L o S One. 7, 8, p. e43212 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TFEB deficiency attenuates mitochondrial degradation upon brown adipose tissue whitening at thermoneutrality
Sass, Frederike, Schlein, C., Jaeckstein, M. Y., Pertzborn, P., Schweizer, M., Schinke, T., Ballabio, A., Scheja, L., Heeren, J. & Fischer, A. W., 1 May 2021, In: Molecular Metabolism. 47, 19 p., 101173.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
THERAPY OF ENDOCRINE DISEASE: Amylin and calcitonin - physiology and pharmacology
Mathiesen, D. S., Lund, A., Holst, Jens Juul, Knop, Filip Krag, Lutz, T. A. & Bagger, J. I., 2022, In: European Journal of Endocrinology. 186, 6, p. R93-R111Research output: Contribution to journal › Review › Research › peer-review
- Published
THU-491-The role of alanine glyoxylate aminotransferase in hepatocellular carcinoma
Satriano, L., Lewinska, Monika, Rourke, C. O., Oliveira, D. V., Bhatt, D. K., Taranta, A., Herr, M., Straub, B., Conner, D. E. A., Budhu, D. A., Pomyen, Y., Ma, Tao, Gerhart-Hines, Zach, Stjernegaard, D. C. S., Matter, M., Crocoll, D. C., Wang, X. W., Marquardt, J. & Andersen, Jesper Bøje, 2019, p. e377.Research output: Contribution to conference › Poster › Research
- Published
TIMP1 overexpression mediates resistance of MCF-7 human breast cancer cells to fulvestrant and down-regulates progesterone receptor expression
Bjerre, C. A., Jensen, L. V., Belling, K. C., Würtz, S. Ø., Yadav, R., Lademann, U. A., Rigina, O., Do, K. N., Ditzel, H. J., Lykkesfeldt, A. E., Wang, J., Nielsen, H. B., Brünner, N., Gupta, R., Rasmussen, A. S. & Stenvang, Jan, 2013, In: Tumor Biology. 34, 6, p. 3839-3851 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TNIK is a conserved regulator of glucose and lipid metabolism in obesity
Pham, Tang Cam Phung, Dollet, L., Ali, Mona Sadek, Raun, Steffen Henning, Møller, Lisbeth L V, Jafari Kermani, Abbas, Ditzel, N., Andersen, Nicoline Resen, Fritzen, Andreas Mæchel, Gerhart-Hines, Zach, Kiens, Bente, Suomalainen, A., Simpson, S. J., Salling Olsen, M., Kieser, A., Schjerling, Peter, Nieminen, A. I., Richter, Erik A., Havula, E. & Sylow, Lykke, 2023, In: Science Advances. 9, 32, 18 p., eadf7119.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TOP-LD: A tool to explore linkage disequilibrium with TOPMed whole-genome sequence data
Huang, L., Rosen, J. D., Sun, Q., Chen, J., Wheeler, M. M., Zhou, Y., Min, Y. I., Kooperberg, C., Conomos, M. P., Stilp, A. M., Rich, S. S., Rotter, J. I., Manichaikul, A., Loos, R. J. F., Kenny, E. E., Blackwell, T. W., Smith, A. V., Jun, G., Sedlazeck, F. J., Metcalf, G. & 6 others, , 2022, In: American Journal of Human Genetics. 109, 6, p. 1175-1181 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TRAF2 mediates JNK and STAT3 activation in response to IL-1β and IFNγ and facilitates apoptotic death of insulin-producing β-cells
Prause, Michala Cecilie Burstein, Berchtold, L. A., Urizar, A. I., Trauelsen, Mette, Billestrup, Nils, Mandrup-Poulsen, Thomas & Størling, Joachim, 15 Jan 2016, In: Molecular and Cellular Endocrinology. 420, p. 24-36 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TRPV1: A Potential Therapeutic Target in Type 2 Diabetes and Comorbidities?
Gram, D. X., Holst, Jens Juul & Szallasi, A., Nov 2017, In: Trends in Molecular Medicine. 23, 11, p. 1002-1013 12 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Target intervention against multiple-risk markers to reduce cardiovascular disease in patients with type 2 diabetes
Gaede, P. & Pedersen, Oluf Borbye, 2004, In: Annals of Medicine. 36, 5, p. 355-66 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Targeted Analysis of Phosphorylated Metabolites in Biological Samples by HILIC–LC–MS
Hodek, O., Jiang, W. & Moritz, Thomas, 2023, In: LC-GC North America. 41, 8, p. 354-355 2 p.Research output: Contribution to journal › Comment/debate › Research
- Published
Targeted Delivery of Butyrate Improves Glucose Homeostasis, Reduces Hepatic Lipid Accumulation and Inflammation in db/db Mice
Pedersen, Signe Schultz, Prause, Michala Cecilie Burstein, Sørensen, C., Størling, Joachim, Moritz, Thomas, Mariño, E. & Billestrup, Nils, 2023, In: International Journal of Molecular Sciences. 24, 5, 17 p., 4533.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Targeted next-generation sequencing as a comprehensive test for patients with and female carriers of DMD/BMD: a multi-population diagnostic study
Wei, X., Dai, Y., Yu, P., Qu, N., Lan, Z., Hong, X., Sun, Y., Yang, G., Xie, S., Shi, Q., Zhou, H., Zhu, Q., Chu, Y., Yao, F., Wang, J., He, J., Yang, Y., Liang, Y., Yang, Y., Qi, M. & 8 others, , 2014, In: European Journal of Human Genetics. 22, p. 110-118 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Targeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment
Fadahunsi, N., Petersen, J. O., Metz, S., Jakobsen, A., Mathiesen, C. V., Buch-Rasmussen, A. S., Kurgan, N. K., Larsen, J. K., Andersen, R. C., Topilko, T., Svendsen, C., Apuschkin, M., Skovbjerg, G., Schmidt, J. H., Houser, G. A., Jager, S. E., Bach, A., Deshmukh, A. S., Kilpeläinen, T. O., Strømgaard, K. & 2 others, , 2024, In: Science Advances. 10, 9, 20 p., eadg2636.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Targeting the intestinal L-cell for obesity and type 2 diabetes treatment
Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Deacon, Carolyn F. & Holst, Jens Juul, 1 Jan 2014, In: Expert Review of Endocrinology & Metabolism. 9, 1, p. 61-72 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tarmbakterier kan have betydning for overvægt i barnealderen
Fonvig, C. E., Pihl, A. F., Hansen, Torben, Pedersen, Oluf Borbye & Holm, Jens-Christian, 18 Aug 2014, In: Ugeskrift for Laeger. 176, p. 2-6 5 p., V03140171.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Temporal gut microbiota variability and association with dietary patterns: From the one-year observational Diet, Cancer, and Health - Next Generations MAX study
Rostgaard-Hansen, Agnetha Linn, Esberg, A., Dicksved, J., Hansen, Torben, Pelve, E., Brunius, C., Halkjær, J., Tjønneland, Anne, Johansson, I. & Landberg, R., 2024, In: American Journal of Clinical Nutrition. 119, 4, p. 1015-1026 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The -250G>A promoter variant in hepatic lipase associates with elevated fasting serum high-density lipoprotein cholesterol modulated by interaction with physical activity in a study of 16,156 Danish subjects
Grarup, N., Andreasen, C. H., Lepola, Mette Andersen, Albrechtsen, Anders, Sandbaek, A., Lauritzen, T., Borch-Johnsen, K., Jørgensen, T., Schmitz, O., Hansen, T. & Pedersen, Oluf Borbye, 2008, In: Journal of Clinical Endocrinology and Metabolism. 93, 6, p. 2294-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The 2-monoacylglycerol moiety of dietary fat appears to be responsible for the fat-induced release of GLP-1 in humans.
Mandøe, M. J., Hansen, K. B., Hartmann, Bolette, Rehfeld, Jens Frederik, Holst, Jens Juul & Hansen, Harald S., 2015, In: The American Journal of Clinical Nutrition. 102, 3, p. 548-555 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The 5-HT1A serotonin receptor is located on calbindin- and parvalbumin-containing neurons in the rat brain
Aznar, S., Qian, Z., Shah, R., Kornum, Birgitte Rahbek & Knudsen, Gitte Moos, 3 Jan 2003, In: Brain Research. 959, 1, p. 58-67 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The PNPLA3 rs738409 G-allele associates with reduced fasting serum triglyceride and serum cholesterol in Danes with impaired glucose regulation
Krarup, N. T., Grarup, Niels, Banasik, Karina, Friedrichsen, M., Færch, K., Sandholt, C. H., Jørgensen, T., Poulsen, P., Witte, D. R., Vaag, Allan, Sørensen, Thorkild I.A., Pedersen, Oluf Borbye & Hansen, Torben, 2012, In: P L o S One. 7, 7, 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The AMPK-related kinase NUAK1 controls cortical axons branching by locally modulating mitochondrial metabolic functions
Lanfranchi, M., Yandiev, S., Meyer-Dilhet, G., Ellouze, S., Kerkhofs, M., Dos Reis, R., Garcia, A., Blondet, C., Amar, A., Kneppers, A., Polvèche, H., Plassard, D., Foretz, M., Viollet, B., Sakamoto, Kei, Mounier, R., Bourgeois, C. F., Raineteau, O., Goillot, E. & Courchet, J., 2024, In: Nature Communications. 15, 17 p., 2487.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Accuracy of Hemoglobin A1c and Fructosamine Evaluated by Long-Term Continuous Glucose Monitoring in Patients with Type 2 Diabetes Undergoing Hemodialysis
Bomholt, T., Rix, M., Almdal, Thomas Peter, Knop, Filip Krag, Rosthøj, Susanne, Heinrich, N. S., Jørgensen, M. B., Larsson, A., Hilsted, Linda, Feldt-Rasmussen, Bo & Hornum, Mads, 2022, In: Blood Purification. 51, p. 608–616 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Airway Microbiota Modulates Effect of Azithromycin Treatment for Episodes of Recurrent Asthma-like Symptoms in Preschool Children: A Randomized Clinical Trial
Thorsen, Jonathan Jan Ilve, Stokholm, Jakob, Rasmussen, Morten Arendt, Mortensen, M. S., Brejnrod, A. D., Hjelmsø, M., Shah, S., Chawes, Bo Lund Krogsgaard, Bønnelykke, Klaus, Sørensen, Søren Johannes & Bisgaard, H., 2021, In: American Journal of Respiratory and Critical Care Medicine. 204, 2, p. 149-158Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Ala/Va198 polymorphism of the hepatocyte nuclear factor-1α gene contributes to the interindividual variation in serum C-peptide response during an oral glucose tolerance test: Evidence from studies of 231 glucose- tolerant first degree relatives of type 2 diabetic probands
Urhammer, Søren Asger, Hansen, Torben, Ekstrøm, Claus Thorn, Eiberg, Hans Rudolf Lytchoff & Pedersen, Oluf Borbye, 1 Dec 1998, In: Journal of Clinical Endocrinology and Metabolism. 83, 12, p. 4506-4509 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Apolipoprotein M/S1P Axis Controls Triglyceride Metabolism and Brown Fat Activity
Christoffersen, Christina, Federspiel, C. K., Borup, A., Christensen, P. M., Madsen, A. N., Heine, M., Nielsen, C. H., Kjaer, A., Holst, Birgitte, Heeren, J. & Nielsen, L. B., 2 Jan 2018, In: Cell Reports. 22, 1, p. 175-188Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Arg82Cys Polymorphism of the Protein Nepmucin Implies a Role in HDL Metabolism
Metz, Sophia, Krarup, N. T., Bryrup, T., Støy, J., Andersson, E. A., Christoffersen, Christina, Neville, M. J., Christiansen, Malene Revsbech, Jonsson, Anna Elisabet, Witte, D. R., Kampmann, U., Nielsen, L. B., Jørgensen, Niklas Rye, Karpe, F., Grarup, Niels, Pedersen, Oluf Borbye, Kilpeläinen, Tuomas O. & Hansen, Torben, 2022, In: Journal of the Endocrine Society. 6, 5, 10 p., bvac034.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The BIGTT test: a novel test for simultaneous measurement of pancreatic beta-cell function, insulin sensitivity, and glucose tolerance
Hansen, Torben, Drivsholm, Thomas, Urhammer, S. A., Palacios, R. T., Vølund, A., Borch-Johnsen, K. & Pedersen, Oluf Borbye, 2007, In: Diabetes Care. 30, 2, p. 257-262 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Biochemical Pathways of Nicotinamide-Derived Pyridones
Hayat, F., Sonavane, M., Makarov, M. V., Trammell, Sam, McPherson, P., Gassman, N. R. & Migaud, M. E., 2021, In: International Journal of Molecular Sciences. 22, 3, 28 p., 1145.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Birth Weight Lowering C-Allele of rs900400 Near LEKR1 and CCNL1 Associates with Elevated Insulin Release following an Oral Glucose Challenge
Andersson, E. A., Harder, M. N., Pilgaard, K., Pisinger, C., Stancáková, A., Kuusisto, J., Grarup, Niels, Færch, K., Poulsen, P., Witte, D. R., Jørgensen, T., Vaag, Allan, Laakso, M., Pedersen, Oluf Borbye & Hansen, Torben, Nov 2011, In: P L o S One. 6, 11, p. e27096 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The C-terminal extension of exendin-4 provides additional metabolic stability when added to GLP-1, while there is minimal effect of truncating exendin-4 in anaesthetized pigs
Simonsen, L., Holst, Jens Juul, Madsen, K. & Deacon, Carolyn F., 10 Feb 2013, In: Regulatory Peptides. 181, 10, p. 17-21 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The C-terminal peptide of CCL21 drastically augments CCL21 activity through the dendritic cell lymph node homing receptor CCR7 by interaction with the receptor N-terminus
Jørgensen, Astrid Sissel, Brandum, E. P., Mikkelsen, J. M., Orfin, K. A., Boilesen, D. R., Egerod, Kristoffer Lihme, Moussouras, N. A., Vilhardt, Frederik, Kalinski, P., Basse, P., Chen, Yen-Hsi, Yang, Zhang, Dwinell, M. B., Volkman, B. F., Veldkamp, C. T., Holst, Peter Johannes, Lahl, K., Goth, C. K., Rosenkilde, Mette & Hjortø, Gertrud Malene, 2021, In: Cellular and Molecular Life Sciences. 78, p. 6963-6978 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The CODATwins Project: The Cohort Description of Collaborative Project of Development of Anthropometrical Measures in Twins to Study Macro-Environmental Variation in Genetic and Environmental Effects on Anthropometric Traits
Silventoinen, K., Jelenkovic, A., Sund, R., Honda, C., Aaltonen, S., Yokoyama, Y., Tarnoki, A. D., Tarnoki, D. L., Ning, F., Ji, F., Pang, Z., Ordoñana, J. R., Sánchez-Romera, J. F., Colodro-Conde, L., Burt, S. A., Klump, K. L., Medland, S. E., Montgomery, G. W., Kandler, C., McAdams, T. A. & 106 others, , Aug 2015, In: Twin Research and Human Genetics. 18, 4, p. 348-60 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The CODATwins Project: The Current Status and Recent Findings of COllaborative Project of Development of Anthropometrical Measures in Twins
Silventoinen, K., Jelenkovic, A., Yokoyama, Y., Sund, R., Sugawara, M., Tanaka, M., Matsumoto, S., Bogl, L. H., Freitas, D. L., Maia, J. A., Hjelmborg, J. V. B., Aaltonen, S., Piirtola, M., Latvala, A., Calais-Ferreira, L., Oliveira, V. C., Ferreira, P. H., Ji, F., Ning, F., Pang, Z. & 118 others, , Dec 2019, In: Twin Research and Human Genetics. 22, 6, p. 800-808Research output: Contribution to journal › Journal article › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity
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Determinants of plasma levels of proglucagon and the metabolic impact of glucagon receptor signalling: a UK Biobank study
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Targeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment
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mTORC1 controls murine postprandial hepatic glycogen synthesis via Ppp1r3b
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