Novo Nordisk Foundation Center for Basic Metabolic Research

The CTRB1/2 locus affects diabetes susceptibility and treatment via the incretin pathway

't Hart, L. M., Fritsche, A., Nijpels, G., van Leeuwen, N., Donnelly, L. A., Dekker, J. M., Alssema, M., Fadista, J., Carlotti, F., Gjesing, A. P., Palmer, C. N. A., van Haeften, T. W., Herzberg-Schäfer, S. A., Simonis-Bik, A. M. C., Houwing-Duistermaat, J. J., Helmer, Q., Deelen, J., Guigas, B., Hansen, T., Machicao, F. & 14 others, Willemsen, G., Heine, R. J., Kramer, M., Holst, Jens Juul, de Koning, E. J. P., Häring, H., Pedersen, Oluf Borbye, Groop, L., de Geus, E. J. C., Slagboom, P. E., Boomsma, D. I., Eekhoff, E. M. W., Pearson, E. R. & Diamant, M., 14 May 2013, In: Diabetes. 62, 9, p. 3275-3281 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The Combination of Fosfomycin, Metronidazole, and Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor is Stable in vitro and Has Maintained Antibacterial Activity

Fonnes, S., Holzknecht, Barbara Juliane, Gasbjerg, Lærke Smidt, Weisser, J. J., Hallberg, H. W., Arpi, M. & Rosenberg, Jacob, 2018, In: Drug Research. 68, 6, p. 349-354

Research output: Contribution to journal › Journal article › Research › peer-review

The Comparative Methylome and Transcriptome After Change of Direction Compared to Straight Line Running Exercise in Human Skeletal Muscle

Maasar, M. F., Turner, D. C., Gorski, P. P., Seaborne, R. A., Strauss, J. A., Shepherd, S. O., Cocks, M., Pillon, N. J., Zierath, Juleen R, Hulton, A. T., Drust, B. & Sharples, A. P., 2021, In: Frontiers in Physiology. 12, 17 p., 619447.

Research output: Contribution to journal › Journal article › Research › peer-review

The Complex Signaling Pathways of the Ghrelin Receptor

Hedegaard, M. A. & Holst, Birgitte, 2020, In: Molecular Endocrinology. 161, 4, 12 p., 020.

Research output: Contribution to journal › Review › Research › peer-review

The Connexin 43 Regulator Rotigaptide Reduces Cytokine-Induced Cell Death in Human Islets

Ghiasi, S. M., Hansen, J. B., Christensen, D. P., Tyrberg, B. & Mandrup-Poulsen, Thomas, 2020, In: International Journal of Molecular Sciences (Online). 21, 12, 15 p., 4311.

Research output: Contribution to journal › Journal article › Research › peer-review

The Danish Adoption Register

Petersen, L. & Sørensen, Thorkild I.A., 2011, In: Scandinavian Journal of Public Health. 39, 7 Suppl, p. 83-6 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The E23K variant of Kir6.2 associates with impaired post-OGTT serum insulin response and increased risk of type 2 diabetes

Nielsen, E. D., Hansen, L., Carstensen, Bendix, Echwald, S. M., Drivsholm, Thomas, Glümer, C., Thorsteinsson, B., Borch-Johnsen, K., Hansen, Torben & Pedersen, Oluf Borbye, 2003, In: Diabetes. 52, 2, p. 573-7 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia: design, results and future prospects

Middeldorp, C. M., Mahajan, A., Horikoshi, M., Robertson, N. R., Beaumont, R. N., Bradfield, J. P., Bustamante, M., Cousminer, D. L., Day, F. R., De Silva, N. M., Guxens, M., Mook-Kanamori, D. O., St Pourcain, B., Warrington, N. M., Adair, L. S., Ahlqvist, E., Ahluwalia, T. S., Almgren, P., Ang, W., Atalay, M. & 463 others, Auvinen, J., Bartels, M., Beckmann, J. S., Bilbao, J. R., Bond, T., Borja, J. B., Cavadino, A., Charoen, P., Chen, Z., Coin, L., Cooper, C., Curtin, J. A., Custovic, A., Das, S., Davies, G. E., Dedoussis, G. V., Duijts, L., Eastwood, P. R., Eliasen, A. U., Elliott, P., Eriksson, J. G., Estivill, X., Fadista, J., Fedko, I. O., Frayling, T. M., Gaillard, R., Gauderman, W. J., Geller, F., Gilliland, F., Gilsanz, V., Granell, R., Grarup, Niels, Groop, L., Hadley, D., Hakonarson, H., Hansen, Torben, Hartman, C. A., Hattersley, A. T., Hayes, M. G., Hebebrand, J., Heinrich, J., Helgeland, O., Henders, A. K., Henderson, J., Henriksen, T. B., Hirschhorn, J. N., Hivert, M., Hocher, B., Holloway, J. W., Holt, P., Hottenga, J., Hypponen, E., Iniguez, C., Johansson, S., Jugessur, A., Kahonen, M., Kalkwarf, H. J., Kaprio, J., Karhunen, V., Kemp, J. P., Kerkhof, M., Koppelman, G. H., Korner, A., Kotecha, S., Kreiner-Moller, E., Kulohoma, B., Kumar, A., Kutalik, Z., Lahti, J., Lappe, J. M., Larsson, H., Lehtimaki, T., Lewin, A. M., Li, J., Lichtenstein, P., Lindgren, C. M., Lindi, V., Linneberg, Allan René, Liu, X., Liu, J., Lowe, W. L. ,. J., Lundstrom, S., Lyytikainen, L., Ma, R. C. W., Mace, A., Magi, R., Magnus, P., Mamun, A. A., Mannikko, M., Martin, N. G., Mbarek, H., McCarthy, N. S., Medland, S. E., Melbye, M., Melen, E., Mohlke, K. L., Monnereau, C., Morgen, C. S., Morris, A. P., Murray, J. C., Myhre, R., Najman, J. M., Nivard, M. G., Nohr, E. A., Nolte, I. M., Ntalla, I., O'Reilly, P., Oberfield, S. E., Oken, E., Oldehinkel, A. J., Pahkala, K., Palviainen, T., Panoutsopoulou, K., Pedersen, Oluf Borbye, Pennell, C. E., Pershagen, G., Pitkanen, N., Plomin, R., Power, C., Prasad, R. B., Prokopenko, I., Pulkkinen, L., Raikkonen, K., Raitakari, O. T., Reynolds, R. M., Richmond, R. C., Rivadeneira, F., Rodriguez, A., Rose, R. J., Salem, R., Santa-Marina, L., Saw, S., Schnurr, T. M., Scott, J. G., Selzam, S., Shepherd, J. A., Simpson, A., Skotte, L., Sleiman, P. M. A., Snieder, H., Sørensen, Thorkild I.A., Standl, M., Steegers, E. A. P., Strachan, D. P., Straker, L., Strandberg, T., Taylor, M., Teo, Y., Thiering, E., Torrent, M., Tyrrell, J., Uitterlinden, A. G., van Beijsterveldt, T., van der Most, P. J., van Duijn, C. M., Viikari, J., Vilor-Tejedor, N., Vogelezang, S., Vonk, J. M., Vrijkotte, T. G. M., Vuoksimaa, E., Wang, C. A., Watkins, W. J., Wichmann, H., Willemsen, G., Williams, G. M., Wilson, J. F., Wray, N. R., Xu, S., Xu, C., Yaghootkar, H., Yi, L., Zafarmand, M. H., Zeggini, E., Zemel, B. S., Hinney, A., Lakka, T. A., Whitehouse, A. J. O., Sunyer, J., Widen, E. E., Feenstra, B., Sebert, S., Jacobsson, B., Njolstad, P. R., Stoltenberg, C., Smith, G. D., Lawlor, D. A., Paternoster, L., Timpson, N. J., Ong, K. K., Bisgaard, H., Bønnelykke, Klaus, Jaddoe, V. W. V., Tiemeier, H., Jarvelin, M., Evans, D. M., Perry, J. R. B., Grant, S. F. A., Boomsma, D. I., Freathy, R. M., McCarthy, M. I., Adair, L. S., Ahlqvist, E., Ahluwalia, Tarun Veer Singh, Almgren, P., Ang, W., Atalay, M., Beaumont, R. N., Beckmann, J. S., Bisgaard, H., Bond, T., Bønnelykke, Klaus, Boomsma, D. I., Borja, J. B., Bradfield, J. P., Bustamante, M., Cavadino, A., Charoen, P., Coin, L., Cooper, C., Cousminer, D. L., Curtin, J. A., Custovic, A., Das, S., Day, F. R., De Silva, N. M., Dedoussis, G. V., Elliott, P., Eriksson, J. G., Evans, D. M., Fadista, J., Feenstra, B., Felix, J. F., Frayling, T. M., Freathy, R. M., Gaillard, R., Geller, F., Gilsanz, V., Grant, S. F. A., Grarup, Niels, Groop, L., Guxens, M., Hadley, D., Hakonarson, H., Hansen, Torben, Hattersley, A. T., Hayes, M. G., Hebebrand, J., Heinrich, J., Helgeland, O., Henriksen, T. B., Hinney, A., Hirschhorn, J. N., Hivert, M., Hocher, B., Holloway, J. W., Horikoshi, M., Hottenga, J., Hypponen, E., Jacobsson, B., Jaddoe, V. W. V., Jarvelin, M., Johansson, S., Kalkwarf, H. J., Kerkhof, M., Korner, A., Kotecha, S., Kreiner-Moller, E., Kulohoma, B., Kutalik, Z., Lakka, T. A., Lappe, J. M., Lawlor, D. A., Lehtimaki, T., Lewin, A. M., Lindgren, C. M., Lindi, V., Linneberg, Allan René, Liu, X., Liu, J., Lowe, W. L. ,. J., Ma, R. C. W., Mace, A., Magi, R., Magnus, P., Mahajan, A., McCarthy, N. S., McCarthy, M. I., Melbye, M., Mohlke, K. L., Monnereau, C., Mook-Kanamori, D. O., Morgen, C. S., Morris, A. P., Murray, J. C., Myhre, R., Njolstad, P. R., Nohr, E. A., Ntalla, I., O'Reilly, P., Oberfield, S. E., Oken, E., Ong, K. K., Panoutsopoulou, K., Pedersen, Oluf Borbye, Pennell, C. E., Perry, J. R. B., Pitkanen, N., St Pourcain, B., Power, C., Prasad, R. B., Prokopenko, I., Raitakari, O. T., Reynolds, R. M., Richmond, R. C., Rodriguez, A., Salem, R., Saw, S., Schnurr, T. M., Sebert, S., Shepherd, J. A., Simpson, A., Skotte, L., Sørensen, Thorkild I.A., Standl, M., Steegers, E. A. P., Strachan, D. P., Sunyer, J., Taylor, M., Teo, Y., Thiering, E., Timpson, N. J., Tyrrell, J., Uitterlinden, A. G., van Duijn, C. M., Vogelezang, S., Vrijkotte, T. G. M., Wang, C. A., Warrington, N. M., Watkins, W. J., Wichmann, H., Widen, E. E., Willemsen, G., Wilson, J. F., Yaghootkar, H., Zafarmand, M. H., Zeggini, E., Zemel, B. S., Ahluwalia, T. S., Auvinen, J., Bartels, M., Bilbao, J. R., Bisgaard, H., Bønnelykke, Klaus, Boomsma, D. I., Bradfield, J. P., Bustamante, M., Chen, Z., Curtin, J. A., Custovic, A., Smith, G. D., Davies, G. E., Duijts, L., Eastwood, P. R., Eliasen, A. U., Estivill, X., Evans, D. M., Fedko, I. O., Felix, J. F., Gauderman, W. J., Gilliland, F., Granell, R., Grant, S. F. A., Guxens, M., Hakonarson, H., Hartman, C. A., Heinrich, J., Henders, A. K., Henderson, J., Holt, P., Hottenga, J., Hypponen, E., Iniguez, C., Jacobsson, B., Jaddoe, V. W. V., Jarvelin, M., Jugessur, A., Kahonen, M., Kaprio, J., Karhunen, V., Kemp, J. P., Koppelman, G. H., Kumar, A., Lahti, J., Larsson, Henrik Bo Wiberg, Lawlor, D. A., Lehtimaki, T., Li, J., Lichtenstein, P., Lundstrom, S., Lyytikainen, L., Magnus, P., Mamun, A. A., Mannikko, M., Martin, N. G., Mbarek, H., Medland, S. E., Melen, E., Middeldorp, C. M., Najman, J. M., Nivard, M. G., Nolte, I. M., Oldehinkel, A. J., Pahkala, K., Palviainen, T., Paternoster, L., Pennell, C. E., Pershagen, G., Pitkanen, N., Plomin, R., St Pourcain, B., Power, C., Pulkkinen, L., Raikkonen, K., Raitakari, O. T., Richmond, R. C., Rivadeneira, F., Rose, R. J., Santa-Marina, L., Scott, J. G., Sebert, S., Selzam, S., Simpson, A., Sleiman, P. M. A., Snieder, H., Standl, M., Stoltenberg, C., Strachan, D. P., Straker, L., Strandberg, T., Sunyer, J., Thiering, E., Tiemeier, H., Timpson, N. J., Torrent, M., Uitterlinden, A. G., van Beijsterveldt, T., van der Most, P. J., van Duijn, C. M., Viikari, J., Vilor-Tejedor, N., Vonk, J. M., Vrijkotte, T. G. M., Vuoksimaa, E., Wang, C. A., Whitehouse, A. J. O., Willemsen, G., Williams, G. M., Wray, N. R., Xu, S., Xu, C., Yi, L. & Zafarmand, M. H., 2019, In: European Journal of Epidemiology. 34, 3, p. 279-300 22 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The Effect of Ethanol on Inflammation Markers and FGF-21 in Healthy Individuals

Lanng, A. R., Gasbjerg, Lærke Smidt, Bergmann, N. C., Møller, H., Gillum, M., Gronbaek, H., Vilsbøll, Tina & Knop, Filip Krag, 2018, In: Diabetes. 67, Supplement 1, 2415-PUB.

Research output: Contribution to journal › Journal article › Research › peer-review

The Effect of Exogenous GLP-1 on Food Intake is Lost in Male Truncally Vagotomized Subjects with Pyloroplasty

Plamboeck, A., Veedfald, Simon, Deacon, Carolyn F., Hartmann, Bolette, Wettergren, A., Svendsen, Lars Bo, Meisner, S., Hovendahl, C., Vilsbøll, Tina, Knop, Filip Krag & Holst, Jens Juul, 18 Apr 2013, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 304, p. G1117-G1127 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The Effect of Overweight and Obesity on Liver Biochemical Markers in Children and Adolescents

Johansen, M. J., Gade, J., Stender, Stefan, Frithioff-Bojsoe, C., Lund, M. A., Chabanova, E., Thomsen, Henrik S., Pedersen, Oluf Borbye, Fonvig, C. E., Hansen, Torben & Holm, Jens-Christian, 2020, In: Journal of Clinical Endocrinology & Metabolism. 105, 2, p. 430-442 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The Effect of PCSK1 Variants on Waist, Waist-Hip Ratio and Glucose Metabolism Is Modified by Sex and Glucose Tolerance Status

Gjesing, A. P., Vestmar, M. A., Jørgensen, T., Heni, M., Holst, Jens Juul, Witte, D. R., Hansen, Torben & Pedersen, Oluf Borbye, 1 Jan 2011, In: P L o S One. 6, 9, p. e23907 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The Effect of Smallpox and Bacillus Calmette-Guérin Vaccination on the Risk of Human Immunodeficiency Virus-1 Infection in Guinea-Bissau and Denmark

Rieckmann, Andreas, Villumsen, M., Jensen, M. L., Ravn, H., da Silva, Z. J., Sørup, S., Baker, J. L., Rodrigues, A., Benn, C. S., Roth, A. E. & Aaby, P., 2017, In: Open Forum Infectious Diseases. 4, 3, 10 p., ofx130.

Research output: Contribution to journal › Journal article › Research › peer-review

The Emerging Role of Epigenetics in Inflammation and Immunometabolism

Raghuraman, S., Donkin, I., Versteyhe, S., Barrès, Romain & Simar, D., 18 Jul 2016, In: Trends in Endocrinology and Metabolism. 27, 11, p. 782-795 14 p.

Research output: Contribution to journal › Review › Research › peer-review

The FOXO3A rs2802292 G-Allele Associates with Improved Peripheral and Hepatic Insulin Sensitivity and Increased Skeletal Muscle-FOXO3A mRNA Expression in Twins

Banasik, Karina, Ribel-Madsen, R., Gjesing, A. P., Wegner, L., Andersson, Åsa, Poulsen, P., Borglykke, A., Witte, D. R., Pedersen, Oluf Borbye, Hansen, Torben & Vaag, Allan, 1 Jan 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 1, p. E119-24

Research output: Contribution to journal › Journal article › Research › peer-review

The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes

Sparsø, T., Andersen, G., Nielsen, T., Burgdorf, K. S., Gjesing, A. M. P., Nielsen, A. L., Albrechtsen, Anders, Rasmussen, S. S., Jørgensen, T., Borch-Johnsen, K., Sandbaek, A., Lauritzen, T., Madsbad, Sten, Hansen, Torben & Pedersen, Oluf Borbye, 2007, In: Diabetologia. 51, 1, p. 70-5 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The GDF15-GFRAL pathway is dispensable for the effects of metformin on energy balance

Klein, A. B., Nicolaisen, T. S., Johann, K., Fritzen, Andreas Mæchel, Mathiesen, C. V., Gil, Cláudia, Pilmark, N. S., Karstoft, Kristian, Blond, Martin Bæk, Quist, Jonas Salling, Seeley, R. J., Færch, K., Lund, Jens, Kleinert, Maximilian & Clemmensen, Christoffer, 2022, In: Cell Reports. 40, 8, 111258.

Research output: Contribution to journal › Journal article › Research › peer-review

The GHB analogue HOCPCA improves deficits in cognition and sensorimotor function after MCAO via CaMKIIα

Griem-Krey, Nane, Klein, A. B., Clausen, B. H., Namini, M. R. J., Nielsen, P. V., Bhuiyan, M., Nagaraja, R. Y., De Silva, T. M., Sobey, C. G., Cheng, H. C., Orset, C., Vivien, D., Lambertsen, K. L., Clarkson, A. N. & Wellendorph, Petrine, 2023, In: Journal of Cerebral Blood Flow and Metabolism. 43, 8, p. 1419-1434

Research output: Contribution to journal › Journal article › Research › peer-review

The GLP-1 receptor agonist lixisenatide reduces postprandial glucose in patients with diabetes secondary to total pancreatectomy: a randomised, placebo-controlled, double-blinded crossover trial

Juel, C. T. B., Lund, A., Andersen, M. M., Hansen, C. P., Storkholm, J. H., Rehfeld, Jens Frederik, van Hall, G., Hartmann, Bolette, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Jul 2020, In: Diabetologia. 63, p. 1285-1298

Research output: Contribution to journal › Journal article › Research › peer-review

The Genetic Basis of Hypertriglyceridemia

Carrasquilla, Germán D., Christiansen, Malene Revsbech & Kilpeläinen, Tuomas O., 2021, In: Current Atherosclerosis Reports. 23, 10 p., 39.

Research output: Contribution to journal › Journal article › Research › peer-review

The Genetic Landscape of Renal Complications in Type 1 Diabetes

Sandholm, N., Van Zuydam, N., Ahlqvist, E., Juliusdottir, T., Deshmukh, H. A., Rayner, N. W., Di Camillo, B., Forsblom, C., Fadista, J., Ziemek, D., Salem, R. M., Hiraki, L. T., Pezzolesi, M., Trégouët, D., Dahlström, E., Valo, E., Oskolkov, N., Ladenvall, C., Marcovecchio, M. L., Cooper, J. & 32 others, Sambo, F., Malovini, A., Manfrini, M., McKnight, A. J., Lajer, M., Harjutsalo, V., Gordin, D., Parkkonen, M., FinnDiane Study Group, F. S. G., Tuomilehto, J., Lyssenko, V., McKeigue, P. M., Rich, S. S., Brosnan, M. J., Fauman, E., Bellazzi, R., Rossing, Peter, Hadjadj, S., Krolewski, A., Paterson, A. D., The DCCT/EDIC Study Group, T. D. S. G., Florez, J. C., Hirschhorn, J. N., Maxwell, A. P., GENIE Consortium, G. C., Dunger, D., Cobelli, C., Colhoun, H. M., Groop, L., McCarthy, M. I., Groop, P. & on behalf of The SUMMIT Consortium, O. B. O. T. S. C., 2017, In: Journal of the American Society of Nephrology. 28, 2, p. 557-574

Research output: Contribution to journal › Journal article › Research › peer-review

The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls

Coleman, J. R. I., Gaspar, H. A., Bryois, J., Byrne, E. M., Forstner, A. J., Holmans, P. A., de Leeuw, C. A., Mattheisen, M., McQuillin, A., Whitehead Pavlides, J. M., Pers, T. H., Ripke, S., Stahl, E. A., Steinberg, S., Trubetskoy, V., Trzaskowski, M., Wang, Y., Abbott, L., Abdellaoui, A., Adams, M. J. & 32 others, Adolfsson, A. N., Agerbo, E., Akil, H., Albani, D., Alliey-Rodriguez, N., Als, T. D., Andlauer, T. F. M., Anjorin, A., Antilla, V., Van der Auwera, S., Awasthi, S., Bacanu, S. A., Badner, J. A., Bækvad-Hansen, M., Barchas, J. D., Bass, N., Bauer, M., Beekman, A. T. F., Belliveau, R., Bergen, S. E., Bigdeli, T. B., Binder, E. B., Bøen, E., Hansen, C. S., Hansen, Thomas Folkmann, Krogh, Jesper, Pedersen, C. B., Pedersen, M. G., Nordentoft, Merete, Werge, Thomas, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, B. D. W. G. O. T. P. G. C. & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, M. D. D. W. G. O. T. P. G. C., 2020, In: Biological Psychiatry. 88, 2, p. 169-184 16 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The Genome of the Netherlands: design, and project goals

Boomsma, D. I., Wijmenga, C., Slagboom, E. P., Swertz, M. A., Karssen, L. C., Abdellaoui, A., Ye, K., Guryev, V., Vermaat, M., van Dijk, F., Francioli, L. C., Hottenga, J. J., Laros, J. F. J., Li, Q., Li, Y., Cao, H., Chen, R., Du, Y., Li, N., Cao, S. & 32 others, van Setten, J., Menelaou, A., Pulit, S. L., Hehir-Kwa, J. Y., Beekman, M., Elbers, C. C., Byelas, H., de Craen, A. J. M., Deelen, P., Dijkstra, M., den Dunnen, J. T., de Knijff, P., Houwing-Duistermaat, J., Koval, V., Estrada, K., Hofman, A., Kanterakis, A., van Enckevort, D., Mai, H., Kattenberg, M., van Leeuwen, E. M., Neerincx, P. B. T., Oostra, B., Rivadeneira, F., Suchiman, E. H. D., Uitterlinden, A. G., Willemsen, G., Wolffenbuttel, B. H., Wang, J., de Bakker, P. I. W., van Ommen, G. & van Duijn, C. M., 2014, In: European Journal of Human Genetics. 22, p. 221-227 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The Glucagon Receptor Antagonist LY2409021 has No Effect on Postprandial Glucose in Type 2 Diabetes

Hædersdal, S., Lund, A., Maagensen, H., Nielsen-Hannerup, E., Gasbjerg, Lærke Smidt, Rosenkilde, Mette, Forman, Julie Lyng, van Hall, Gerrit, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2022, In: European Journal of Endocrinology. 186, 2, p. 207-221 15 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The Gluco- and Liporegulatory and Vasodilatory Effects of Glucose-Dependent Insulinotropic Polypeptide (GIP) Are Abolished by an Antagonist of the Human GIP Receptor

Asmar, M., Asmar, A., Simonsen, L., Gasbjerg, Lærke Smidt, wbf943, wbf943, Rosenkilde, Mette, Hartmann, Bolette, Dela, Flemming, Holst, Jens Juul & Bülow, J., Sep 2017, In: Diabetes. 66, 9, p. 2363-2371 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The Gly482Ser genotype at the PPARGC1A gene and elevated blood pressure: a meta-analysis involving 13,949 individuals

Vimaleswaran, K. S., Luan, J., Andersen, G., Muller, Y. L., Wheeler, E., Brito, E. C., O'Rahilly, S., Pedersen, Oluf Borbye, Baier, L. J., Knowler, W. C., Barroso, I., Wareham, N. J., Loos, R. J. F. & Franks, P. W., 2008, In: Journal of Applied Physiology. 105, 4, p. 1352-8 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The Glycemic Effect of Liraglutide Evaluated by Continuous Glucose Monitoring in Persons with Type 2 Diabetes Receiving Dialysis

Bomholt, T., Idorn, T., Knop, Filip Krag, Jørgensen, M. B., Ranjan, A. G., Resuli, M., Hansen, P. M., Borg, Rikke, Persson, F., Feldt-Rasmussen, Bo & Hornum, Mads, 2021, In: Nephron. 145, 1, p. 27-34

Research output: Contribution to journal › Journal article › Research › peer-review

The Greenland population health survey 2018 - methods of a prospective study of risk factors for lifestyle related diseases and social determinants of health amongst Inuit

Bjerregaard, P., Larsen, C. V. L., Olesen, I., Ottendahl, C. B., Backer, Vibeke, Senftleber, N., Christensen, M. M. B., Larsen, T. J., Byberg, S., Hansen, Torben & Jørgensen, M. E., 2022, In: International Journal of Circumpolar Health. 81, 1, 11 p., 2090067.

Research output: Contribution to journal › Journal article › Research › peer-review

The Gut: A Key to the Pathogenesis of Type 2 Diabetes?

Holst, Jens Juul, Pedersen, Jens, Albrechtsen, Nicolai Jacob Wewer & Knop, Filip Krag, Aug 2017, In: Metabolic Syndrome and Related Disorders. 15, 6, p. 259-262 4 p.

Research output: Contribution to journal › Review › Research › peer-review

The Gut Microbiota Modulates Energy Metabolism in the Hibernating Brown Bear Ursus arctos

Sommer, F., Ståhlman, M., Ilkayeva, O., Arnemo, J. M., Kindberg, J., Josefsson, J., Newgard, C. B., Fröbert, O. & Bäckhed, G. F., 3 Feb 2016, In: Cell Reports. 14, 7, p. 1655-1661 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The Gut Microbiota in Prediabetes and Diabetes: A Population-Based Cross-Sectional Study

Wu, H., Tremaroli, V., Schmidt, C., Lundqvist, A., Olsson, L. M., Kramer, M., Gummesson, A., Perkins, R., Bergstrom, G. & Backhed, F., 2020, In: Cell Metabolism. 32, 3, p. 379-390.e3 15 p.

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The HADHSC gene encoding short-chain L-3-hydroxyacyl-CoA dehydrogenase (SCHAD) and type 2 diabetes susceptibility: the DAMAGE study

van Hove, E. C., Hansen, Torben, Dekker, J. M., Reiling, E., Nijpels, G., Jørgensen, T., Borch-Johnsen, K., Hamid, Y. H., Heine, R. J., Pedersen, Oluf Borbye, Maassen, J. A. & hart, L. M., 2006, In: Diabetes. 55, 11, p. 3193-6 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The HETE Is on FFAR1 and Pancreatic Islet Cells

Trauelsen, Mette, Lückmann, Michael, Frimurer, Thomas Michael & Schwartz, Thue W., 2018, In: Cell Metabolism. 27, 2, p. 273-275 3 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The Human Intestinal Microbiome in Health and Disease

Lynch, S. V. & Pedersen, Oluf Borbye, 15 Dec 2016, In: New England Journal of Medicine. 375, 24, p. 2369-2379 11 p.

Research output: Contribution to journal › Review › Research › peer-review

The Impact of Dietary Fiber on Gut Microbiota in Host Health and Disease

Makki, K., Deehan, E. C., Walter, J. & Backhed, F., 2018, In: Cell Host & Microbe. 23, 6, p. 705-715

Research output: Contribution to journal › Review › Research › peer-review

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

Winkler, T. W., Justice, A. E., Graff, M., Barata, L., Feitosa, M. F., Chu, S., Czajkowski, J., Esko, T., Fall, T., Kilpeläinen, T. O., Lu, Y., Mägi, R., Mihailov, E., Pers, T. H., Rüeger, S., Teumer, A., Ehret, G. B., Ferreira, T., Heard-Costa, N. L., Karjalainen, J. & 31 others, Lagou, V., Mahajan, A., Neinast, M. D., Prokopenko, I., Simino, J., Teslovich, T. M., Jansen, R., Westra, H., White, C. C., Absher, D., Ahluwalia, Tarun Veer Singh, Ahmad, S., Albrecht, E., Alves, A. C., Bragg-Gresham, J. L., de Craen, A. J. M., Bis, J. C., Bonnefond, A., Boucher, G., Banasik, Karina, Grarup, Niels, Hansen, Torben, Jørgensen, T., Krarup, N. T., Linneberg, Allan René, Ribel-Madsen, R., Sparsø, T. H., Melbye, M., Pedersen, Oluf Borbye, Sørensen, Thorkild I.A. & CHARGE Consortium, C. C., 1 Oct 2015, In: P L o S Genetics. 11, 10, p. 1-42 42 p., e1005378.

Research output: Contribution to journal › Journal article › Research › peer-review

The Intestinotrophic Effects of Glucagon-Like Peptide-2 in Relation to Intestinal Neoplasia

Orhan, Adile, Gögenur, Ismail & Kissow, Hannelouise, 2018, In: The Journal of clinical endocrinology and metabolism. 103, 8, p. 2827-2837

Research output: Contribution to journal › Review › Research › peer-review

The KCNMB1 Glu65Lys polymorphism associates with reduced systolic and diastolic blood pressure in the Inter99 study of 5729 Danes.

Nielsen, T., Burgdorf, K. S., Grarup, Niels, Borch-Johnsen, K., Hansen, T., Jørgensen, T., Pedersen, Oluf Borbye & Andersen, G., 2008, In: Journal of Hypertension. 26, 11, p. 2142-6 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The KDM5 family is required for activation of pro-proliferative cell cycle genes during adipocyte differentiation

Brier, A. B., Loft, A., Madsen, J. G. S., Rosengren, T., Nielsen, R., Schmidt, S. F., Liu, Z., Yan, Q., Gronemeyer, H. & Mandrup, S., 28 Feb 2017, In: Nucleic Acids Research. 45, 4, p. 1743-1759 17 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The L-alpha-amino acid receptor GPRC6A is expressed in the islets of Langerhans but is not involved in L-arginine-induced insulin release

Smajilovic, S., Clemmensen, Christoffer, Johansen, L. D., Wellendorph, Petrine, Holst, Jens Juul, Thams, P. G., Ogo, E. & Bräuner, Hans, 2013, In: Amino Acids. 44, 2, p. 383-390 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The Limits of Exercise Physiology: From Performance to Health

Gabriel, B. M. & Zierath, Juleen R, 2 May 2017, In: Cell Metabolism. 25, 5, p. 1000-1011 12 p.

Research output: Contribution to journal › Review › Research › peer-review

The Liver-Alpha Cell Axis in Health and in Disease

Richter, Michael Martin, Galsgaard, Katrine Douglas, Elmelund, E., Knop, Filip Krag, Suppli, M. P., Holst, Jens Juul, Winther-Sørensen, Marie, Kjeldsen, Sasha Alexandra Sampson & Albrechtsen, Nicolai Jacob Wewer, 2022, In: Diabetes. 71, +, p. 1852–1861

Research output: Contribution to journal › Review › Research › peer-review

The Living Room: En gentænkning af museumsgenstandes endeligt

Grünfeld, Martin, 2021, In: Danske Museer. 34

Research output: Contribution to journal › Journal article › Communication

The Location of Missense Variants in the Human GIP Gene Is Indicative for Natural Selection

Lindquist, Peter, Gasbjerg, Lærke Smidt, Mokrosinski, J., Holst, Jens Juul, Hauser, Alexander Sebastian & Rosenkilde, Mette, 2022, In: Frontiers in Endocrinology. 13, 14 p., 891586.

Research output: Contribution to journal › Journal article › Research › peer-review

The Many Faces of Gaia’s Response-ability: A Field Trip to the Critical Zones Digital Platform

Formosinho, Joana, 2022, In: Museums Worlds: Advances in Research. 10, p. 181-192 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The Matola malaria project: a temporal and spatial study of malaria transmission and disease in a suburban area of Maputo, Mozambique

Thompson, R., Begtrup, K., Cuamba, N., Dgedge, M., Mendis, C., Gamage-Mendis, A., Enosse, S. M., Barreto, J., Sinden, R. E. & Høgh, Birthe, Nov 1997, In: American Journal of Tropical Medicine and Hygiene. 57, 5, p. 550-9 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The Metabolic Role and Therapeutic Potential of the Microbiome

Olofsson, L. E. & Backhed, F., 2022, In: Endocrine Reviews. 43, p. 907-926

Research output: Contribution to journal › Review › Research › peer-review

The MicroRNA Repertoire in Enteroendocrine Cells: Identification of miR-375 as a Potential Regulator of the Enteroendocrine Lineage

Knudsen, L. A., Petersen, N., Schwartz, Thue W. & Egerod, Kristoffer Lihme, Nov 2015, In: Endocrinology. 156, 11, p. 3971-83 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The Microbiota and Epigenetic Regulation of T Helper 17/Regulatory T Cells: In Search of a Balanced Immune System

Luo, A., Leach, S. T., Barrès, Romain, Hesson, L. B., Grimm, M. C. & Simar, D., 2017, In: Frontiers in Immunology. 8, 14 p., 417.

Research output: Contribution to journal › Review › Research › peer-review

The Molecular Diversity of Vagal Afferents Revealed

Egerod, Kristoffer Lihme, Schwartz, Thue W. & Gautron, L., 2019, In: Trends in Neurosciences. 42, 10, p. 663-666

Research output: Contribution to journal › Editorial › Research › peer-review

The N363S polymorphism of the glucocorticoid receptor and metabolic syndrome factors in men

Buemann, B., Black, E., Holst, C., Toubro, S., Echwald, S., Pedersen, Oluf Borbye, Astrup, A. & Sørensen, Thorkild I.A., 2005, In: Obesity Research. 13, 5, p. 862-867 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The Novel Mas agonist, CGEN-856S, Attenuates Isoproterenol-Induced Cardiac Remodeling and Myocardial Infarction Injury in Rats

Savergnini, S. Q., Ianzer, D., Carvalho, M. B. L., Ferreira, A. J., Silva, G. A. B., Marques, F. D., Peluso, A. A. B., Beiman, M., Cojocaru, G., Cohen, Y., Almeida, A. P., Rotman, G. & Santos, R. A. S., 1 Mar 2013, In: PLoS ONE. 8, 3, e57757.

Research output: Contribution to journal › Journal article › Research › peer-review

The PPAR gamma 2 Pro12Ala variant predicts ESRD and mortality in patients with type 1 diabetes and diabetic nephropathy

Jorsal, A., Tarnow, L., Lajer, M., Ek, J., Hansen, Torben, Pedersen, Oluf Borbye & Parving, H., 2008, In: Molecular Genetics and Metabolism. 94, 3, p. 347-51 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The Pentapeptide RM-131 Promotes Food Intake and Adiposity in Wildtype Mice but Not in Mice Lacking the Ghrelin Receptor

Fischer, K., Finan, B., Clemmensen, Christoffer, van der Ploeg, L. H. T., Tschöp, M. H. & Müller, T. D., 2014, In: Frontiers in Nutrition. 1, p. 31

Research output: Contribution to journal › Journal article › Research › peer-review

The Polygenic and Monogenic Basis of Blood Traits and Diseases

Vuckovic, D., Bao, E. L., Akbari, P., Lareau, C. A., Mousas, A., Jiang, T., Chen, M-H., Raffield, L. M., Tardaguila, M., Huffman, J. E., Ritchie, S. C., Megy, K., Ponstingl, H., Penkett, C. J., Albers, P. K., Wigdor, E. M., Sakaue, S., Moscati, A., Manansala, R., Lo, K. S. & 31 others, Qian, H., Akiyama, M., Bartz, T. M., Ben-Shlomo, Y., Beswick, A., Bork-Jensen, J., Bottinger, E. P., Brody, J. A., van Rooij, F. J. A., Chitrala, K. N., Wilson, P. W. F., Choquet, H., Danesh, J., Di Angelantonio, E., Dimou, N., Ding, J., Elliott, P., Esko, T., Evans, M. K., Felix, S. B., Floyd, J. S., Broer, L., Grarup, Niels, Guo, M. H., Guo, Q., Greinacher, A., Hansen, Torben, Linneberg, Allan René, Pedersen, Oluf Borbye, Loos, R. J. F. & VA Million Veteran Program, V. M. V. P., 2020, In: Cell. 182, 5, p. 1214-1231 29 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The Prevalence of Polyneuropathy in Type 2 Diabetes Subgroups Based on HOMA2 Indices of β-Cell Function and Insulin Sensitivity

Kristensen, F. P. B., Christensen, D. H., Callaghan, B. C., Stidsen, J. V., Nielsen, J. S., Højlund, K., Beck-Nielsen, H., Jensen, T. S., Andersen, H., Vestergaard, P., Jessen, N., Olsen, M. H., Hansen, Torben, Brøns, C., Vaag, Allan, Sørensen, H. T. & Thomsen, R. W., 2023, In: Diabetes Care. 46, 8, p. 1546-1555 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The Promise of Selecting Individuals from the Extremes of Exposure in the Analysis of Gene-Physical Activity Interactions

Osazuwa-Peters, O. L., Schwander, K., Waken, R. J., de Las Fuentes, L., Kilpeläinen, Tuomas O., Loos, R. J. F., Racette, S. B., Sung, Y. J. & Rao, D. C., 2019, In: Human Heredity. 83, 6, p. 315-332

Research output: Contribution to journal › Journal article › Research › peer-review

The Rab-GTPase-activating protein TBC1D1 regulates skeletal muscle glucose metabolism

Szekeres, F., Chadt, A., Tom, R. Z., Deshmukh, Atul Shahaji, Chibalin, A. V., Björnholm, M., Al-Hasani, H. & Zierath, Juleen R, 15 Aug 2012, In: American Journal of Physiology: Endocrinology and Metabolism. 303, 4, p. E524-33

Research output: Contribution to journal › Journal article › Research › peer-review

The Renal Extraction and the Natriuretic Action of GLP-1 in Humans Depend on Interaction With the GLP-1 Receptor

Asmar, A., Cramon, P. K., Asmar, M., Simonsen, L., Sorensen, Charlotte Mehlin, Madsbad, Sten, Hartmann, Bolette, Holst, Jens Juul, Hovind, P., Jensen, B. L. & Bülow, J., 2021, In: Journal of Clinical Endocrinology and Metabolism. 106, 1, p. e11-e19 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The Role of D-allulose and Erythritol on the Activity of the Gut Sweet Taste Receptor and Gastrointestinal Satiation Hormone Release in Humans: A Randomized, Controlled Trial

Teysseire, F., Bordier, V., Budzinska, A., Weltens, N., Rehfeld, Jens Frederik, Holst, Jens Juul, Hartmann, Bolette, Beglinger, C., Van Oudenhove, L., Wölnerhanssen, B. K. & Meyer-Gerspach, A. C., 2022, In: Journal of Nutrition. 152, 5, p. 1228–1238,

Research output: Contribution to journal › Journal article › Research › peer-review

The Role of Glucagon in the Pathophysiology and Treatment of Type 2 Diabetes

Hædersdal, S., Lund, A., Knop, Filip Krag & Vilsbøll, Tina, 2018, In: Mayo Clinic Proceedings. 93, 2, p. 217-239

Research output: Contribution to journal › Review › Research › peer-review

The Role of the Gut Microbiota in Childhood Obesity

Pihl, A. F., Fonvig, C. E., Stjernholm, T., Hansen, Torben, Pedersen, Oluf Borbye & Holm, Jens-Christian, 25 Jul 2016, In: Childhood Obesity. 12, 4, p. 292-299 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The Sensory Mechanisms of Nutrient-Induced GLP-1 Secretion

Hjørne, A. P., Modvig, Ida Marie & Holst, Jens Juul, 2022, In: Metabolites. 12, 5, 15 p., 420.

Research output: Contribution to journal › Review › Research › peer-review

The T allele of rs7903146 TCF7L2 is associated with impaired insulinotropic action of incretin hormones, reduced 24 h profiles of plasma insulin and glucagon, and increased hepatic glucose production in young healthy men

Pilgaard, K., Jensen, C., Schou, J., Lyssenko, V., Wegner, L., Brøns, C., Vilsbøll, T., Hansen, T., Madsbad, S., Holst, J., Vølund, A., Poulsen, P., Groop, L., Pedersen, O., Vaag, A., Pilgaard, K., Jensen, C. B., Schou, J. H., Lyssenko, V., Wegner, L. & 10 others, Brøns, C., Vilsbøll, T., Hansen, T., Madsbad, Sten, Holst, J. M., Vølund, A., Poulsen, P., Groop, L., Pedersen, O. & Vaag, A., 1 Jul 2009, In: Diabetologia. 52, 7, p. 1298-307 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The T-allele of TCF7L2 rs7903146 associates with a reduced compensation of insulin secretion for insulin resistance induced by 9 days of bed rest

Alibegovic, A. C., Sonne, M. P., Højbjerre, L., Hansen, T., Pedersen, Oluf Borbye, van Hall, Gerrit, Holst, Jens Juul, Stallknecht, Bente Merete, Dela, Flemming & Vaag, A., 2010, In: Diabetes. 59, 4, p. 836-43 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The Taste Liking Questionnaire (TasteLQ) – A tool for assessment of taste liking in the Danish population

Haydar, Sara, Karlsson, Camilla Cederbye, Linneberg, Allan René, Kårhus, L. L., Ängquist, Lars, Hansen, Torben, Bredie, Wender & Grarup, Niels, 2024, In: Food Quality and Preference. 117, 12 p., 105176.

Research output: Contribution to journal › Journal article › Research › peer-review

The Treeterbi and Parallel Treeterbi algorithms: efficient, optimal decoding for ordinary, generalized and pair HMMs.

Keibler, E., Arumugam, Mani & Brent, M. R., Mar 2007, In: Bioinformatics. 23, 5, p. 545-554 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The Tweeting Museum

Noesgaard, D. & Gerdes, N., 2014, In: Meddelelser om Konservering. 2014, 2, p. 30 31 p.

Research output: Contribution to journal › Journal article › Communication

The Type 2 Diabetes Risk Allele of TMEM154-rs6813195 Associates with Decreased Beta Cell Function in a Study of 6,486 Danes

Balslev-Harder, M., Appel, E. V. R., Grarup, Niels, Gjesing, A. M. P., Ahluwalia, Tarun Veer Singh, Jørgensen, T., Christensen, C., Brandslund, I., Linneberg, Allan René, Sørensen, Thorkild I.A., Pedersen, Oluf Borbye & Hansen, Torben, 2015, In: PLOS ONE. 10, 3, p. 1-13 13 p., e0120890.

Research output: Contribution to journal › Journal article › Research › peer-review

The U-shaped association of body mass index with mortality: Influence of the traits height, intelligence, and education

Jørgensen, Terese Sara Høj, Osler, Merete, Ängquist, Lars, Zimmermann, E., Okholm, Gunhild Tidemann & Sørensen, Thorkild I.A., Oct 2016, In: Obesity. 24, 10, p. 2240–2247 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The Use of Gastrostomy Tube for the Long-Term Remission of Hyperinsulinemic Hypoglycemia After Roux-en-y Gastric Bypass: A Case Report

Craig, C., Lamendola, C., Holst, Jens Juul, Deacon, Carolyn F. & McLaughlin, T., 2015, In: AACE Clinical Case Reports. 1, 2, p. e84-e87 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The VGF-Derived Neuropeptide TLQP-21 Shows No Impact on Hormone Secretion in the Isolated Perfused Rat Pancreas

Christiansen, Charlotte Bayer, Svendsen, B. & Holst, Jens Juul, 20 Jan 2015, In: Hormone and Metabolic Research. 47, 07, p. 537-43 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The Value of Rare Genetic Variation in the Prediction of Common Obesity in European Ancestry Populations

Wang, Z., Choi, S. W., Chami, N., Boerwinkle, E., Fornage, M., Redline, S., Bis, J. C., Brody, J. A., Psaty, B. M., Kim, W., McDonald, M. L. N., Regan, E. A., Silverman, E. K., Liu, C. T., Vasan, R. S., Kalyani, R. R., Mathias, R. A., Yanek, L. R., Arnett, D. K., Justice, A. E. & 21 others, North, K. E., Kaplan, R., Heckbert, S., de Andrade, M., Guo, X., Lange, L. A., Rich, S., Rotter, J. I., Ellinor, P. T., Lubitz, S. A., Blangero, J., Shoemaker, M. B., Darbar, D., Gladwin, M. T., Albert, C. M., Chasman, D. I., Jackson, R. D., Kooperberg, C., Reiner, A. P., O’Reilly, P. F. & Loos, Ruth, 2022, In: Frontiers in Endocrinology. 13, 12 p., 863893.

Research output: Contribution to journal › Journal article › Research › peer-review

The Vicious Circle of Hepatic Glucagon Resistance in Non-Alcoholic Fatty Liver Disease

Galsgaard, Katrine Douglas, 2020, In: Journal of Clinical Medicine. 9, 12, 11 p., 4049.

Research output: Contribution to journal › Review › Research › peer-review

The Zinc-Sensing Receptor GPR39 in Physiology and as a Pharmacological Target

Laitakari, Anna Isabella, Liu, L., Frimurer, Thomas Michael & Holst, Birgitte, 2021, In: International Journal of Molecular Sciences. 22, 8, 22 p., 3872.

Research output: Contribution to journal › Review › Research › peer-review

The absence of GH signaling affects the susceptibility to high-fat diet-induced hypothalamic inflammation in male mice

Baquedano, E., Ruiz-Lopez, A. M., Sustarsic, E. G., Herpy, J., List, E. O., Chowen, J. A., Frago, L. M., Kopchick, J. J. & Argente, J., Dec 2014, In: Endocrinology. 155, 12, p. 4856-67 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The acute effects of dietary carbohydrate reduction on postprandial responses of non-esterified fatty acids and triglycerides: a randomized trial

Samkani, A., fbg982, fbg982, Anholm, C., Astrup, A., Deacon, Carolyn F., Holst, Jens Juul, Madsbad, S., Boston, R., Krarup, T. & Haugaard, Steen Bendix, 2018, In: Lipids in Health and Disease. 17, 9 p., 295.

Research output: Contribution to journal › Journal article › Research › peer-review

The adhesion G protein-coupled receptor G2 (ADGRG2/GPR64) constitutively activates SRE and NFκB and is involved in cell adhesion and migration

Cornelia Peeters, M., Fokkelman, M., Boogaard, B., Egerod, Kristoffer Lihme, van de Water, B., IJzerman, A. P. & Schwartz, Thue W., Dec 2015, In: Cellular Signalling. 27, 12, p. 2579-88 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The angiotensin type 2 receptor and the kidney

Peluso, A. A. B., Santos, R. A. S., Unger, T. & Steckelings, U. M., 2017, In: Current Opinion in Nephrology and Hypertension.

Research output: Contribution to journal › Journal article › Research › peer-review

The anorectic and thermogenic effects of pharmacological lactate in male mice are confounded by treatment osmolarity and co-administered counterions

Lund, J., Breum, A. W., Gil, C., Falk, S., Sass, F., Isidor, M. S., Dmytriyeva, O., Ranea-Robles, P., Mathiesen, C. V., Basse, A. L., Johansen, O. S., Fadahunsi, N., Lund, C., Nicolaisen, T. S., Klein, A. B., Ma, T., Emanuelli, B., Kleinert, M., Sørensen, C. M., Gerhart-Hines, Z. & 1 others, Clemmensen, Christoffer, 2023, In: Nature Metabolism. 5, 4, p. 677-698 22 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The anorexic hormone Peptide YY_3-36 is rapidly metabolized to inactive Peptide YY_3-34 in vivo.

Toräng, S., Veedfald, Simon, Rosenkilde, Mette, Hartmann, Bolette & Holst, Jens Juul, 20 Jul 2015, In: Physiological Reports. 3, 7, p. 1-8 8 p., e12455.

Research output: Contribution to journal › Journal article › Research › peer-review

The anti-obesogenic effect of lean fish species is influenced by the fatty acid composition in fish fillets

Fjære, E., Myrmel, L. S., Dybing, K., Kuda, O., Jensen, Benjamin Anderschou Holbech, Rossmeisl, M., Frøyland, L., Kristiansen, Karsten & Madsen, L., 2020, In: Nutrients. 12, 10, 18 p., 3038.

Research output: Contribution to journal › Journal article › Research › peer-review

The antidepressant-like effect of probiotics and their faecal abundance may be modulated by the cohabiting gut microbiota in rats

Abildgaard, A., Kern, T., Pedersen, Oluf Borbye, Hansen, Torben, Wegener, G. & Lund, S., 2019, In: European Neuropsychopharmacology. 29, 1, p. 98-110

Research output: Contribution to journal › Journal article › Research › peer-review

The antiresorptive effect of GIP, but not GLP-2, is preserved in patients with hypoparathyroidism - a randomized crossover study

Skov-Jeppesen, Kirsa, Hepp, N., Oeke, J., Hansen, M. S., Jafari Kermani, Abbas, Svane, M. S., Balenga, N., Olson, J. A., Frost, M., Kassem, Moustapha Saad El-Deen, Madsbad, Sten, Jensen, Jens-Erik Beck, Holst, Jens Juul, Rosenkilde, Mette & Hartmann, Bolette, 2021, In: Journal of Bone and Mineral Research. 36, 8, p. 1448-1458 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The arginine of the DRY motif in transmembrane segment III functions as a balancing micro-switch in the activation of the β2-adrenergic receptor

Hansen, L. V., Groenen, M., Nygaard, R., Frimurer, Thomas Michael, Holliday, N. D. & Schwartz, Thue W., 14 Sep 2012, In: Journal of Biological Chemistry. 287, 38, p. 31973-82 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The aromatic amino acid sensor GPR142 controls metabolism through balanced regulation of pancreatic and gut hormones

Rudenko, Olga, Shang, J., Munk, A., Ekberg, J. P., Petersen, N., Engelstoft, M. S., Egerod, Kristoffer Lihme, Hjorth, Siv Annegrethe, Wu, M., Feng, Y., Zhou, Y., Mokrosinski, J., Thams, P., Reimann, F., Gribble, F., Rehfeld, Jens Frederik, Holst, Jens Juul, Treebak, Jonas Thue, Howard, A. D. & Schwartz, Thue W., 2019, In: Molecular Metabolism. 19, p. 49-64 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The association between candidate migraine susceptibility loci and severe migraine phenotype in a clinical sample

Esserlind, A., Christensen, A. F., Steinberg, S., Grarup, Niels, Pedersen, Oluf Borbye, Hansen, Torben, Werge, Thomas, Hansen, T. F., Husemoen, L. L. N., Linneberg, Allan René, Budtz-Joergensen, Esben, Westergaard, M. L., Stefansson, H. & Olesen, Jes, 2016, In: Cephalalgia : an international journal of headache. 36, 7, p. 1-9 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The association between the val/ala-55 polymorphism of the uncoupling protein 2 gene and exercise efficiency

Buemann, B., Schierning, B., Toubro, S., Bibby, B. M., Sørensen, Thorkild I.A., Dalgaard, L., Pedersen, Oluf Borbye & Astrup, A., 2001, In: International Journal of Obesity. 25, p. 467-471 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The association of IgA deficiency on infection rate, self-perceived health, and levels of C-reactive protein in healthy blood donors

Hauge, S. C., Jensen, C. K., Nielsen, L. K., Pedersen, Oluf Borbye, Sørensen, E., Thørner, L. W., Hjalgrim, H., Erikstrup, C., Nielsen, K. R., Kaspersen, K. A., Didriksen, Maria, Dziegiel, Morten Hanefeld & Ullum, H., 1 Mar 2018, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 126, 3, p. 248-256 9 p.

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The association of alcohol and alcohol metabolizing gene variants with diabetes and coronary heart disease risk factors in a white population

Husemoen, L. L. N., Jørgensen, T., Borch-Johnsen, K., Hansen, Torben, Pedersen, Oluf Borbye & Linneberg, Allan René, 1 Jan 2010, In: P L o S One. 5, 8, p. e11735

Research output: Contribution to journal › Journal article › Research › peer-review

The association of cardiometabolic, diet and lifestyle parameters with plasma glucagon-like peptide-1: An IMI DIRECT study

Eriksen, R., White, M. C., Dawed, A. Y., Perez, I. G., Posma, J. M., Haid, M., Sharma, S., Prehn, C., Thomas, L. E., Koivula, R. W., Bizzotto, R., Mari, A., Giordano, G. N., Pavo, I., Schwenk, J. M., De Masi, F., Tsirigos, K. D., Brunak, S., Viñuela, A., Mahajan, A. & 26 others, McDonald, T. J., Kokkola, T., Rutters, F., Beulens, J., Muilwijk, M., Blom, M., Elders, P., Hansen, T. H., Fernandez-Tajes, J., Jones, A., Jennison, C., Walker, M., McCarthy, M. I., Pedersen, Oluf Borbye, Ruetten, H., Forgie, I., Holst, Jens Juul, Thomsen, Henrik S., Ridderstråle, M., Bell, J. D., Adamski, J., Franks, P. W., Hansen, Torben, Holmes, E., Frost, G. & Pearson, E. R., 2024, (E-pub ahead of print) In: Journal of Clinical Endocrinology and Metabolism.

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The authors reply

Idorn, T., Knop, Filip Krag, Jørgensen, M., Holst, Jens Juul, Hornum, Mads & Feldt-Rasmussen, Bo, Jan 2014, In: Kidney International. 85, 1, p. 212-3 2 p.

Research output: Contribution to journal › Letter › Research › peer-review

The bile acid-sequestering resin sevelamer eliminates the acute GLP-1 stimulatory effect of endogenously released bile acids in patients with type 2 diabetes

Brønden, A., Albér, A., Rohde, U., Gasbjerg, Lærke Smidt, Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 1 Feb 2018, In: Diabetes, Obesity and Metabolism. 20, 2, p. 362-369

Research output: Contribution to journal › Journal article › Research › peer-review

The biochemistry and physiology of long-chain dicarboxylic acid metabolism

Ranea-Robles, Pablo & Houten, S. M., 2023, In: Biochemical Journal. 480, 9, p. 607-627 21 p.

Research output: Contribution to journal › Review › Research › peer-review

The biology of glucagon and the consequences of hyperglucagonemia

Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Pedersen, Jens, Knop, Filip Krag & Holst, Jens Juul, 9 Sep 2016, In: Biomarkers in Medicine. 10, 11, p. 1141-1151 11 p.

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The blunted effect of glucose-dependent insulinotropic polypeptide in subcutaneous abdominal adipose tissue in obese subjects is partly reversed by weight loss

Asmar, M., Arngrim, N., Simonsen, L., Asmar, A., Nordby, P., Holst, Jens Juul & Bülow, J., 2016, In: Nutrition and Diabetes. 6, 7 p., e208.

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The brominated flame retardant PBDE 99 promotes adipogenesis via regulating mitotic clonal expansion and PPARγ expression

Wen, Q., Xie, X., Zhao, C., Ren, Q., Zhang, X., Wei, D., Emanuelli, Brice & Du, Y., 2019, In: The Science of the Total Environment. 670, p. 67-77 11 p.

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The cAMP/PKA Pathway Rapidly Activates SIRT1 to Promote Fatty Acid Oxidation Independently of Changes in NAD ⁺

Gerhart-Hines, Zach, Dominy, J. E., Blättler, S. M., Jedrychowski, M. P., Banks, A. S., Lim, J. H., Chim, H., Gygi, S. P. & Puigserver, P., 23 Dec 2011, In: Molecular Cell. 44, 6, p. 851-863 13 p.

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The chemistry of the vitamin B₃ metabolome

Makarov, M. V., Trammell, Sam & Migaud, M. E., 2019, In: Biochemical Society Transactions. 47, 1, p. 131-147

Research output: Contribution to journal › Review › Research › peer-review