Novo Nordisk Foundation Center for Basic Metabolic Research

  1. Published
  2. Published

    Protocol for a single-centre, parallel-group, randomised, controlled, superiority trial on the effects of time-restricted eating on body weight, behaviour and metabolism in individuals at high risk of type 2 diabetes: the REStricted Eating Time (RESET) study

    Quist, Jonas Salling, Jensen, M. M., Clemmensen, K. K. B., Pedersen, H., Bjerre, N., Størling, Joachim, Blond, M. B., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Torekov, Signe Sørensen, Vistisen, D., Jørgensen, M. E., Panda, S., Brock, C., Finlayson, G. & Faerch, K., 2020, In: BMJ Open. 10, 8, 11 p., 037166.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Protocol for flow cytometry-assisted single-nucleus RNA sequencing of human and mouse adipose tissue with sample multiplexing

    Gulko, A., Essene, A., Belmont-Rausch, Dylan Matthew, Veregge, M., Pant, D., Tenen, D., Kapel, Benedicte Schultz, Emont, M. P., Pers, Tune H, Rosen, E. D. & Tsai, L. T., 2024, In: STAR Protocols. 5, 1, 21 p., 102893.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Protocol for qPCR analysis that corrects for cDNA amplification efficiency

    Damgaard, Mads Vargas & Treebak, Jonas Thue, 2022, In: STAR Protocols. 3, 3, 11 p., 101515.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Protocol for the combined cardiometabolic deep phenotyping and registry-based 20-year follow-up study of the Inter99 cohort

    Bjørnsbo, K. S., Brøns, C., Aadahl, M., Kampmann, F. B., Friis Bryde Nielsen, C., Lundbergh, B., Christensen, R. W., Kårhus, L. L., Madsen, A. L., Hansen, C. S., Nørgaard, K., Jørgensen, N. R., Suetta, C., Kjaer, M., Grarup, N., Kanters, J., Larsen, M., Køber, L., Kofoed, K. F., Loos, R. & 3 others, Hansen, Torben, Linneberg, Allan René & Vaag, Allan, 2024, In: BMJ Open. 14, 1, 10 p., e078501.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published
  7. Published

    Protocol to characterize mitochondrial supercomplexes from mouse tissues by combining BN-PAGE and MS-based proteomics

    Moreno Justicia, Roger, Gonzalez-Franquesa, A., Stocks, Ben Nicholas & Deshmukh, Atul Shahaji, 2022, In: STAR Protocols. 3, 1, 21 p., 101135.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Prototype of an evidence-based tool to aid individualized treatment for type 2 diabetes

    Buse, J. B., Holst, I., Knop, Filip Krag, Kvist, K., Thielke, D. & Pratley, R., 2021, In: Diabetes, Obesity and Metabolism. 23, 7, p. 1666-1671

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Provision of amniotic fluid during parenteral nutrition increases weight gain with limited effects on gut structure, function, immunity, and microbiology in newborn preterm pigs

    Østergaard, M. V., Shen, René Liang, Støy, A. C. F., Skovgaard, K., Krych, Ł., Leth, S. S., Nielsen, Dennis Sandris, Hartmann, Bolette, Bering, S. B., Schmidt, M. & Sangild, Per Torp, 2016, In: Journal of Parenteral and Enteral Nutrition. 40, 4, p. 552-566 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Pten knockout in mouse preosteoblasts leads to changes in bone turnover and strength.

    Lorenz, J., Richter, S., Kirstein, A. S., Kolbig, F., Nebe, M., Schulze, M., Kiess, W., Spitzbarth, I., Kloting, N., Le Duc, D., Baschant, U. & Garten, A., 2024, In: JBMR Plus. 8, 3, 14 p., ziad016.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Pterostilbene Fails to Rescue Insulin Secretion and Sensitivity in Multiple Murine Models of Diabetes

    Damgaard, Mads Vargas, Jepsen, Sara Lind, Ashcroft, Stephen Paul, Holst, Jens Juul & Treebak, Jonas Thue, 2022, In: Nutrients. 14, 18, 11 p., 3741.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Public Science Communication

    Whiteley, Louise, 2015, RCR – A Danish textbook for courses in Responsible Conduct of Research. Jensen, K. K., Whiteley, L. & Sandøe, P. (eds.). Frederiksberg, p. 90-107

    Research output: Chapter in Book/Report/Conference proceedingBook chapterEducation

  13. Published

    Pulmonary maternal immune activation does not cross the placenta but leads to fetal metabolic adaptation

    Hansen, Signe Schmidt Kjølner, Krautz, Robert, Rago, D., Havelund, J., Stigliani, Arnaud, Færgeman, N. J., Prézelin, A., Rivière, J., Couturier-Tarrade, A., Akimov, V., Blagoev, B., Elfving, B., Neess, D., Vogel, U., Khodosevich, Konstantin, Hougaard, Karin Sørig & Sandelin, Albin Gustav, 2024, In: Nature Communications. 15, 24 p., 4711.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Putting the brain in its place

    Whiteley, Louise, 7 Jul 2017, In: Times Higher Education. p. 42-43 2 p.

    Research output: Contribution to journalLiterature reviewCommunication

  15. Published

    Pyruvate dehydrogenase kinase regulates vascular inflammation in atherosclerosis and increases cardiovascular risk

    Forteza, M. J., Berg, M., Edsfeldt, A., Sun, J., Baumgartner, R., Kareinen, I., Casagrande, F. B., Hedin, U., Zhang, S., Vuckovic, I., Dzeja, P. P., Polyzos, K. A., Gisterå, A., Trauelsen, M., Schwartz, T. W., Dib, L., Herrmann, J., Monaco, C., Matic, L., Gonçalves, I. & 1 others, Ketelhuth, D. F. J., 2023, In: Cardiovascular Research. 119, 7, p. 1524-1536 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Pyruvate kinase M2 represses thermogenic gene expression in brown adipocytes

    Isidor, Marie Sophie, Winther, Sally, Markussen, L. K., Basse, A. L., Quistorff, B., Nedergaard, J., Emanuelli, Brice & Hansen, Jacob B., 2020, In: FEBS Letters. 594, 7, p. 1218-1225

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Quality control and conduct of genome-wide association meta-analyses

    Winkler, T. W., Day, F. R., Croteau-Chonka, D. C., Wood, A. R., Locke, A. E., Mägi, R., Ferreira, T., Fall, T., Graff, M., Justice, A. E., Luan, J., Gustafsson, S., Randall, J. C., Vedantam, S., Workalemahu, T., Kilpeläinen, T., Scherag, A., Esko, T., Kutalik, Z., Heid, I. M. & 2 others, Loos, Ruth & Genetic Investigation of Anthropometric Traits (GIANT) Consortium, G. I. O. A. T. (. C., May 2014, In: Nature Protocols (Online). 9, 5, p. 1192-1212 21 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Quality of dietary fat and genetic risk of type 2 diabetes: individual participant data meta-analysis

    Merino, J., Guasch-Ferré, M., Ellervik, C., Dashti, H. S., Sharp, S. J., Wu, P., Overvad, K., Sarnowski, C., Kuokkanen, M., Lemaitre, R. N., Justice, A. E., Ericson, U., Braun, K. V. E., Mahendran, Y., Frazier-Wood, A. C., Sun, D., Chu, A. Y., Tanaka, T., Luan, J., Hong, J. & 48 others, Tjønneland, Anne, Ding, M., Lundqvist, A., Mukamal, K., Rohde, R., Schulz, C., Franco, O. H., Grarup, N., Chen, Y. I., Bazzano, L., Franks, P. W., Buring, J. E., Langenberg, C., Liu, C., Hansen, Torben, Jensen, Majken Karoline, Sääksjärvi, K., Psaty, B. M., Young, K. L., Hindy, G., Sandholt, C. H., Ridker, P. M., Ordovas, J. M., Meigs, J. B., Pedersen, Oluf Borbye, Kraft, P., Perola, M., North, K. E., Orho-Melander, M., Voortman, T., Toft, Ulla Marie Nørgaard, Rotter, J. I., Qi, L., Forouhi, N. G., Mozaffarian, D., Sørensen, Thorkild I.A., Stampfer, M. J., Männistö, S., Selvin, E., Imamura, F., Salomaa, V., Hu, F. B., Wareham, N. J., Dupuis, J., Smith, C. E., Kilpeläinen, Tuomas O., Chasman, D. I. & Florez, J. C., 2019, In: BMJ (Clinical research ed.). 366, p. l4292

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Quality of life improves in children and adolescents during a community-based overweight and obesity treatment

    Mollerup, P. M., Nielsen, T. R. H., Bøjsøe, C., Kloppenborg, J. T., Baker, J. L. & Holm, Jens-Christian, Jun 2017, In: Quality of Life Research. 26, 6, p. 1597-1608

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Quality of life in children and adolescents with overweight or obesity: Impact of obstructive sleep apnea

    Fenger, K. N., Andersen, I. G., Holm, L. A., Holm, Jens-Christian & Homøe, Preben, 2020, In: International Journal of Pediatric Otorhinolaryngology. 138, 110320.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Quality of life, patient satisfaction, and cardiovascular outcomes of the randomised 2 x 3 factorial Copenhagen insulin and Metformin therapy (CIMT) trial – A detailed statistical analysis plan

    Olsen, M. H., Almdal, Thomas Peter, Madsbad, Sten, Ovesen, C., Gluud, C., Sneppen, S. B., Breum, Leif, Hedetoft, C., Krarup, T., Lundby-Christensen, L., Mathiesen, Elisabeth, Røder, M. E., drb459, drb459, Wiinberg, N. & Jakobsen, J. C., 2023, In: Contemporary Clinical Trials Communications. 33, 101095.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Quantification of oxidative stress phenotypes based on high-throughput growth profiling of protein kinase and phosphatase knockouts.

    Altıntaş, Ali, 11 Nov 2015, In: FEMS Yeast Research.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Quantification of the contribution of GLP-1 to mediating insulinotropic effects of DPP-4 inhibition with vildagliptin in healthy subjects and type 2-diabetic patients using exendin [9-39] as a GLP-1 receptor antagonist.

    Nauck, M. A., Kind, J., Köthe, L. D., Holst, Jens Juul, Deacon, Carolyn F., Broschag, M., He, Y., Kjems, L. & Foley, J., 2016, In: Diabetes. 65, 8, p. 2440-2447 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Quantifying Diet-Induced Metabolic Changes of the Human Gut Microbiome

    Shoaie, S., Ghaffari, P., Kovatcheva-Datchary, P., Mardinoglu, A., Sen, P., Pujos-Guillot, E., de Wouters, T., Juste, C., Rizkalla, S., Chilloux, J., Hoyles, L., Nicholson, J. K., Dore, J., Dumas, M. E., Clement, K., Bäckhed, G. F., Nielsen, J. & MICRO-Obes Consortium, M. C., 4 Aug 2015, In: Cell Metabolism. 22, 2, p. 320-31 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Quantitative Phosphoproteomics of the Angiotensin AT2-Receptor Signaling Network Identifies HDAC1 (Histone-Deacetylase-1) and p53 as Mediators of Antiproliferation and Apoptosis

    Peluso, A. A., Kempf, S. J., Verano-braga, T., Rodrigues-ribeiro, L., Johansen, L. E., Hansen, M. R., Kitlen, G., Haugaard, A. H., Sumners, C., Ditzel, H. J., Santos, R. A., Bader, M., Larsen, M. R. & Steckelings, U. M., 2022, In: Hypertension. 79, 11, p. 2530-2541

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Quantitative differences in synthetic gut microbial inoculums do not affect the final stabilized in vitro community compositions

    Gnanasekaran, Thiyagarajan, Sarathi, Arjun, Fang, Q., Azarm, A., Geraldo, Juliana Assis, Nigro, E. & Arumugam, Mani, 2023, In: mSystems. 8, 4, 16 p., e0124922.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Quantitative perfusion assessment of intestinal anastomoses in pigs treated with glucagon-like peptide 2

    Nerup, N., Ring, L. L., Strandby, R. B., Egeland, C., Svendsen, M. B. S., Hasselby, Jane Preuss, Willemoe, G. L., Hartmann, Bolette, Svendsen, Lars Bo & Achiam, Michael Patrick, 2018, In: Langenbeck's Archives of Surgery. 403, 7, p. 881-889

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Quantitative phosphoproteomic analysis of IRS1 in skeletal muscle from men with normal glucose tolerance or type 2 diabetes: A case-control study

    Karlsson, H. K. R., Kasahara, A., Ikeda, M., Chibalin, A. V., Harada, J., Rydén, M., Krook, A., Kato, M., Kubota, K. & Zierath, Juleen R, 2021, In: Metabolism. 118, 7 p., 154726.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Quantitative proteomics and single-nucleus transcriptomics of the sinus node elucidates the foundation of cardiac pacemaking

    Linscheid, N., Logantha, S. J. R. J., Poulsen, C., Zhang, S., Schrölkamp, Maren, Egerod, Kristoffer Lihme, Thompson, J. J., Kitmitto, A., Galli, G., Humphries, M. J., Zhang, H., Pers, Tune H, Olsen, Jesper Velgaard, Boyett, M. & Lundby, Alicia, 2019, In: Nature Communications. 10, 19 p., 2889.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Questioning the fetal microbiome illustrates pitfalls of low-biomass microbial studies

    Kennedy, K. M., de Goffau, M. C., Perez-Muñoz, M. E., Arrieta, M. C., Bäckhed, F., Bork, P., Braun, T., Bushman, F. D., Dore, J., de Vos, W. M., Earl, A. M., Eisen, J. A., Elovitz, M. A., Ganal-Vonarburg, S. C., Gänzle, M. G., Garrett, W. S., Hall, L. J., Hornef, M. W., Huttenhower, C., Konnikova, L. & 26 others, Lebeer, S., Macpherson, A. J., Massey, R. C., McHardy, A. C., Koren, O., Lawley, T. D., Ley, R. E., O’Mahony, L., O’Toole, P. W., Pamer, E. G., Parkhill, J., Raes, J., Rattei, T., Salonen, A., Segal, E., Segata, N., Shanahan, F., Sloboda, D. M., Smith, G. C. S., Sokol, H., Spector, T. D., Surette, M. G., Tannock, G. W., Walker, A. W., Yassour, M. & Walter, J., 2023, In: Nature. 613, 7945, p. 639-649 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  31. Published

    Quinazoline compounds and their use in MCH-related disease

    Frimurer, Thomas Michael, Ulven, Trond, Högberg, T., Nørregaard, P. K., Little, P. B., Receveur, J. & Grimstrup, M., 2005, Patent No. WO 2005/123714

    Research output: Patent

  32. Published

    Quinoline compounds for use in MCH receptor related disorders

    Frimurer, Thomas Michael, Ulven, Trond, Högberg, T., Nørregaard, P. K., Little, P. B. & Receveur, J., 2004, Patent No. WO 2004/052370

    Research output: Patent

  33. Published

    R package for Non-sex-of-parent-specific Transmission Ratio Distortion

    Huang, L. O., 2014

    Research output: Non-textual formComputer programmeResearch

  34. Published

    R package for Sex-of-Parent-specific Transmission Ratio Distortion

    Huang, L. O., 2015

    Research output: Non-textual formComputer programmeResearch

  35. Published

    RAIN: RNA-protein Association and Interaction Networks

    Junge, A., Refsgaard, J. C., Garde, C., Pan, X., Santos, A., Alkan, F., Anthon, Christian, von Mering, C., Workman, C. T., Jensen, Lars Juhl & Gorodkin, Jan, 2017, In: Database: The Journal of Biological Databases and Curation. 2017, 9 p., baw167.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    RANKL regulates testicular cancer growth and Denosumab treatment has suppressive effects on GCNIS and advanced seminoma

    Andreassen, C. H., Lorenzen, M., Nielsen, J. E., Kafai Yahyavi, S., Toft, Birgitte Grønkær, Ingerslev, L. R., Clemmensen, Christoffer, Rasmussen, Lene Juel, Bokemeyer, C., Juul, Anders, Jørgensen, A. & Jensen, M. B., 2022, In: British Journal of Cancer. 127, p. 408-421

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    RCR - A Danish textbook for courses in Responsible Conduct of Research

    Jensen, Karsten Klint (ed.), Whiteley, Louise (ed.) & Sandøe, Peter (ed.), Jan 2018, 3 ed. Frederiksberg: Department of Food and Resource Economics, University of Copenhagen. 115 p.

    Research output: Book/ReportBookEducation

  38. Published

    RCR - A Danish textbook for courses in Responsible Conduct of Research

    Jensen, Karsten Klint (ed.), Whiteley, Louise (ed.) & Sandøe, Peter (ed.), 2017, 2 ed. Frederiksberg: Department of Food and Resource Economics, University of Copenhagen. 109 p.

    Research output: Book/ReportBookEducation

  39. Published

    RCR - A Danish textbook for courses in Responsible Conduct of Research

    Jensen, Karsten Klint (ed.), Andersen, M. M. (ed.), Whiteley, Louise (ed.) & Sandøe, Peter (ed.), May 2020, 4 ed. Frederiksberg: Department of Food and Resource Economics, University of Copenhagen. 130 p.

    Research output: Book/ReportBookEducation

  40. Published

    RCR - A Danish textbook for courses in Responsible Conduct of Research [1. ed.]

    Jensen, Karsten Klint (ed.), Whiteley, Louise (ed.) & Sandøe, Peter (ed.), 2015, 1st edition ed. Frederiksberg: Department of Food and Resource Economics, University of Copenhagen. 107 p.

    Research output: Book/ReportBookEducation

  41. Published

    RETRACTION: Glucose-Dependent Insulinotropic Polypeptide Increases Blood Flow in Adipose Tissue of Humans by Recruiting Capillaries (Retraction of Vol 104, Pg 16, 2019)

    Asmar, M., Asmar, A., Simonsen, L., Holst, Jens Juul & Bulow, J., 2019, In: Journal of Clinical Endocrinology & Metabolism. 104, 1, p. W1-W9

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    RFRP Neurons - The Doorway to Understanding Seasonal Reproduction in Mammals

    Henningsen, J. B., Gauer, F. & Simonneaux, V., 2016, In: Frontiers in Endocrinology. 7, p. 36

    Research output: Contribution to journalReviewResearchpeer-review

  43. Published

    RNA sequencing unravels novel L cell constituents and mechanisms of GLP-1 secretion in human gastric bypass-operated intestine

    Miskelly, M. G., Lindqvist, A., Piccinin, E., Hamilton, A., Cowan, E., Nergård, B. J., Del Giudice, R., Ngara, M., Cataldo, L. R., Kryvokhyzha, D., Volkov, P., Engelking, L., Artner, I., Lagerstedt, J. O., Eliasson, L., Ahlqvist, E., Moschetta, A., Hedenbro, J. & Wierup, N., 2023, In: Diabetologia. 67, 2, p. 356-370

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    RNA-Seq and Mass-Spectrometry-Based Lipidomics Reveal Extensive Changes of Glycerolipid Pathways in Brown Adipose Tissue in Response to Cold

    Marcher, A., Loft, A., Nielsen, R., Vihervaara, T., Madsen, J. G. S., Sysi-Aho, M., Ekroos, K. & Mandrup, S., 1 Dec 2015, In: Cell Reports. 13, 9, p. 2000-13 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    RNase L controls terminal adipocyte differentiation, lipids storage and insulin sensitivity via CHOP10 mRNA regulation

    Fabre, O. M. J., Salehzada, T., Lambert, K., Boo Seok, Y., Zhou, A., Mercier, J. & Bisbal, C., Sep 2012, In: Cell Death and Differentiation. 19, 9, p. 1470-81 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    ROS-induced ribosome impairment underlies ZAKα-mediated metabolic decline in obesity and aging

    Snieckute, G., Ryder, L., Vind, A. C., Wu, Z., Arendrup, F. S., Stoneley, M., Chamois, S., Martinez-Val, A., Leleu, M., Dreos, R., Russell, A., Gay, D. M., Genzor, A. V., Choi, B. S-Y., Basse, A. L., Sass, F., Dall, M., Dollet, L. C. M., Blasius, M., Willis, A. E. & 10 others, Lund, Anders H., Treebak, Jonas Thue, Olsen, Jesper Velgaard, Poulsen, Steen Seier, Pownall, M. E., Jensen, Benjamin Anderschou Holbech, Clemmensen, Christoffer, Gerhart-Hines, Zach, Gatfield, D. & Bekker-Jensen, Simon Holst, 2023, In: Science (New York, N.Y.). 382, 6675, 14 p., eadf3208.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Radio-immunoassays for glucagon-like peptides 1 and 2 (GLP-1 and GLP-2)

    Ørskov, Cathrine & Holst, Jens Juul, Apr 1987, In: Scandinavian Journal of Clinical and Laboratory Investigation. Supplement. 47, 2, p. 165-74 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Radioiodine and aggravation of Graves' ophthalmopathy

    drb459, drb459 & Laurberg, P., 1 Jul 1989, In: Lancet. 2, 8653, p. 47

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Radioiodine treatment of recurrent hyperthyroidism in patients previously treated for Graves' disease by subtotal thyroidectomy

    drb459, drb459 & Laurberg, P., Jan 1992, In: Journal of Internal Medicine. 231, 1, p. 13-7 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Radiojodbehandling af recidiverende hypertyreose hos patienter som tidligere er behandlet for diffus toksisk struma med subtotal strumektomi

    drb459, drb459 & Laurberg, P., 2 Aug 1993, In: Ugeskrift for Laeger. 155, 31, p. 2403-5 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review