Novo Nordisk Foundation Center for Basic Metabolic Research

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  1. 2023
  2. Published

    Cross-species comparison of pregnancy-induced GDF15

    Klein, A. B., Ranea-Robles, Pablo, Nicolaisen, T. S., Gil, Cláudia, Johann, K., Prats Quesada, Júlia, Pistoljevic, N., Hviid, K. V. R., Olsen, L. F., Offersen, Simone Margaard, Helge, Jørn Wulff, Nielsen, Henriette Svarre, Bakker, J., Kleinert, Maximilian & Clemmensen, Christoffer, 2023, In: American Journal of Physiology - Endocrinology and Metabolism. 325, 4, p. E303-E309

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    AMPKα2 is a skeletal muscle stem cell intrinsic regulator of myonuclear accretion

    Kneppers, A., Ben Larbi, S., Theret, M., Saugues, A., Dabadie, C., Gsaier, L., Ferry, A., Rhein, P., Gondin, J., Sakamoto, Kei & Mounier, R., 2023, In: iScience. 26, 12, 17 p., 108343.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    The Prevalence of Polyneuropathy in Type 2 Diabetes Subgroups Based on HOMA2 Indices of β-Cell Function and Insulin Sensitivity

    Kristensen, F. P. B., Christensen, D. H., Callaghan, B. C., Stidsen, J. V., Nielsen, J. S., Højlund, K., Beck-Nielsen, H., Jensen, T. S., Andersen, H., Vestergaard, P., Jessen, N., Olsen, M. H., Hansen, Torben, Brøns, C., Vaag, Allan, Sørensen, H. T. & Thomsen, R. W., 2023, In: Diabetes Care. 46, 8, p. 1546-1555 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    The naturally occurring GIP(1-30)NH2 is a GIP receptor agonist in humans

    Krogh, L. S. L., Henriksen, K., Stensen, S., Skov-Jeppesen, Kirsa, Bergmann, N. C., Størling, Joachim, Rosenkilde, Mette, Hartmann, Bolette, Holst, Jens Juul, Gasbjerg, Lærke Smidt & Knop, Filip Krag, 2023, In: European Journal of Endocrinology. 188, 1, lvac015.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Atorvastatin for patients with cirrhosis. A randomized, placebo-controlled trial

    Kronborg, T. M., Schierwagen, R., Trošt, K., Gao, Q., Moritz, Thomas, Bendtsen, Flemming, Gantzel, R. H., Andersen, M. L., Teisner, A. S., Grønbæk, H., Hobolth, L., Møller, Søren, Trebicka, J. & Kimer, N., 2023, In: Hepatology Communications. 7, 12, 11 p., e0332.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    GWAS of random glucose in 476,326 individuals provide insights into diabetes pathophysiology, complications and treatment stratification

    Lagou, V., Jiang, L., Ulrich, A., Zudina, L., González, K. S. G., Balkhiyarova, Z., Faggian, A., Maina, J. G., Chen, S., Todorov, P. V., Sharapov, S., David, A., Marullo, L., Mägi, R., Rujan, R. M., Ahlqvist, E., Thorleifsson, G., Gao, Η., Εvangelou, Ε., Benyamin, B. & 78 others, Scott, R. A., Isaacs, A., Zhao, J. H., Willems, S. M., Johnson, T., Gieger, C., Grallert, H., Meisinger, C., Müller-Nurasyid, M., Strawbridge, R. J., Goel, A., Rybin, D., Albrecht, E., Jackson, A. U., Stringham, H. M., Corrêa, I. R., Farber-Eger, E., Steinthorsdottir, V., Uitterlinden, A. G., Munroe, P. B., Brown, M. J., Schmidberger, J., Holmen, O., Thorand, B., Hveem, K., Wilsgaard, T., Mohlke, K. L., Wang, Z., den Hoed, M., Shmeliov, A., den Hoed, M., Loos, Ruth, Kratzer, W., Haenle, M., Koenig, W., Boehm, B. O., Tan, T. M., Tomas, A., Salem, V., Barroso, I., Tuomilehto, J., Boehnke, M., Florez, J. C., Hamsten, A., Watkins, H., Njølstad, I., Wichmann, H. E., Caulfield, M. J., Khaw, K. T., van Duijn, C. M., Hofman, A., Wareham, N. J., Langenberg, C., Whitfield, J. B., Martin, N. G., Montgomery, G., Scapoli, C., Tzoulaki, I., Elliott, P., Thorsteinsdottir, U., Stefansson, K., Brittain, E. L., McCarthy, M. I., Froguel, P., Sexton, P. M., Wootten, D., Groop, L., Dupuis, J., Meigs, J. B., Deganutti, G., Demirkan, A., Pers, Tune H, Reynolds, C. A., Aulchenko, Y. S., Kaakinen, M. A., Jones, B., Prokopenko, I. & van Duijn, C. M., 2023, In: Nature Genetics. 55, 9, p. 1448-1461 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Sex differences in muscle protein expression and DNA methylation in response to exercise training

    Landen, S., Jacques, M., Hiam, D., Alvarez-Romero, J., Schittenhelm, R. B., Shah, A. D., Huang, C., Steele, J. R., Harvey, N. R., Haupt, L. M., Griffiths, L. R., Ashton, K. J., Lamon, S., Voisin, S. & Eynon, N., 2023, In: Biology of Sex Differences. 14, 20 p., 56.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Self-organized metabotyping of obese individuals identifies clusters responding differently to bariatric surgery

    Lappa, D., Meijnikman, A. S., Krautkramer, K. A., Olsson, L. M., Aydin, Ö., Van Rijswijk, A. S., Acherman, Y. I. Z., De Brauw, M. L., Tremaroli, V., Olofsson, L. E., Lundqvist, A., Hjorth, Siv Annegrethe, Ji, B., Gerdes, V. E. A., Groen, A. K., Schwartz, Thue W., Nieuwdorp, M., Bäckhed, F. & Nielsen, J., 2023, In: PLoS ONE. 18, 3, 26 p., e0279335.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    High-throughput proteomics uncovers exercise training and type 2 diabetes-induced changes in human white adipose tissue

    Larsen, Jeppe Kjærgaard, Kruse, R., Sahebekhtiari, N., Moreno Justicia, Roger, Jorba, G. G., Petersen, M. H., de Almeida, M. E., Ørtenblad, N., Deshmukh, Atul Shahaji & Højlund, K., 2023, In: Science Advances. 9, 48, 16 p., eadi7548.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Oral glucose has little or no effect on appetite and satiety sensations despite a significant gastrointestinal response

    Lauritsen, J. V., Bergmann, N., Junker, A. E., Gyldenløve, Mette, Skov, Lone, Gluud, Lise Lotte, Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2023, In: European Journal of Endocrinology. 189, 6, p. 619-626 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Birth weight, childhood body mass index, and risk of diverticular disease in adulthood

    Laursen, A. S. D., Jensen, B. W., Strate, L. L., Sørensen, Thorkild I.A., Baker, J. L. & Sørensen, H. T., 2023, In: International Journal of Obesity. 47, p. 207–214 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    A single-cell, time-resolved profiling of Xenopus mucociliary epithelium reveals nonhierarchical model of development

    Lee, J., Møller, A. F., Chae, S., Bussek-Sedzinski, Alexandra Maria, Park, T. J., Kim, Y., Lee, H. S., Pers, Tune H, Kwon, T., Sedzinski, Jakub & Natarajan, K. N., 2023, In: Science Advances. 9, 14, p. eadd5745 23 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Editorial: Healthy adipose tissue expansion

    Lee, K. Y., Emanuelli, Brice & Ussar, S., 2023, In: Frontiers in Cell and Developmental Biology. 11, 3 p., 1287533.

    Research output: Contribution to journal › Editorial › Research

  15. Published

    Ancestral diversity in lipoprotein(a) studies helps address evidence gaps

    Lee, M. P., Dimos, S. F., Raffield, L. M., Wang, Z., Ballou, A. F., Downie, C. G., Arehart, C. H., Correa, A., De Vries, P. S., Du, Z., Gignoux, C. R., Gordon-Larsen, P., Guo, X., Haessler, J., Howard, A. G., Hu, Y., Kassahun, H., Kent, S. T., Lopez, J. A. G., Monda, K. L. & 14 others, North, K. E., Peters, U., Preuss, M. H., Rich, S. S., Rhodes, S. L., Yao, J., Yarosh, R., Tsai, M. Y., Rotter, J. I., Kooperberg, C. L., Loos, Ruth, Ballantyne, C., Avery, C. L. & Graff, M., 2023, In: Open Heart. 10, 2, 11 p., e002382.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Effects of different doses of exercise and diet-induced weight loss on beta-cell function in type 2 diabetes (DOSE-EX): a randomized clinical trial

    Legaard, G. E., Lyngbæk, M. P. P., Almdal, T. P., Karstoft, K., Bennetsen, S. L., Feineis, C. S., Nielsen, N. S., Durrer, C. G., Liebetrau, B., Nystrup, U., Østergaard, M., Thomsen, K., Trinh, B., Solomon, T. P. J., Van Hall, G., Brønd, J. C., Holst, J. J., Hartmann, B., Christensen, R., Pedersen, B. K. & 1 others, Ried-Larsen, M., 2023, In: Nature Metabolism. 5, p. 880–895

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Fungi and bacteria in the beds of rural and urban infants correlate with later risk of atopic diseases

    Lehtimäki, J., Gupta, S., Hjelmsø, M., Shah, S., Thorsen, Jonathan Jan Ilve, Rasmussen, Morten Arendt, Soverini, M., Li, Xuan Ji, Russel, J., Trivedi, Urvish, Brix, S., Bønnelykke, Klaus, Chawes, Bo Lund Krogsgaard, Bisgaard, H., Sørensen, Søren Johannes & Stokholm, Jakob, 2023, In: Clinical and Experimental Allergy. 53, 12, p. 1268-1278 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Molecular Consequences of Peripheral Influenza A Infection on Cell Populations in the Murine Hypothalamus

    Lemcke, René, Jensen, Christine Egebjerg, Pagh-Berendtsen, Nicolai, Egerod, Kristoffer Lihme, Thomsen, Allan Randrup, Pers, Tune H, Christensen, Jan Pravsgaard & Kornum, Birgitte Rahbek, 2023, 31 p.

    Research output: Working paper › Preprint › Research

  19. Published

    Molecular consequences of peripheral Influenza A infection on cell populations in the murine hypothalamus

    Lemcke, René, Jensen, Christine Egebjerg, Pagh-Berendtsen, Nicolai, Egerod, Kristoffer Lihme, Thomsen, Allan Randrup, Pers, Tune H, Christensen, Jan Pravsgaard & Kornum, Birgitte Rahbek, 2023, In: eLife. 12, 28 p., RP87515.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    The effect of traditional diet on glucose homeostasis in carriers and non-carriers of a common TBC1D4 variant in Greenlandic Inuit: A randomized crossover study

    Lewis, Jack Ivor, Lind, M. V., Møller, G., Hansen, Torben, Pedersen, H., Christensen, M. M. B., Laursen, J. C., Nielsen, S., Ottendahl, C. B., Larsen, C. V. L., Stark, K. D., Bjerregaard, P., Jørgensen, M. E. & Lauritzen, Lotte, 2023, In: British Journal of Nutrition. 130, 11, p. 1871-1884

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Improving Mitochondrial Function in Skeletal Muscle Contributes to the Amelioration of Insulin Resistance by Nicotinamide Riboside

    Li, Q., Jiang, Xuye, Zhou, Y., Gu, Y., Ding, Y., Luo, J., Pang, N., Sun, Y., Pei, L., Pan, J., Gao, M., Ma, S., Xiao, Y., Hu, D., Wu, F. & Yang, L., 2023, In: International Journal of Molecular Sciences. 24, 12, 19 p., 10015.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    A statistical framework for powerful multi-trait rare variant analysis in large-scale whole-genome sequencing studies

    Li, X., Chen, H., Selvaraj, M. S., Van Buren, E., Zhou, H., Wang, Y., Sun, R., McCaw, Z. R., Yu, Z., Arnett, D. K., Bis, J. C., Blangero, J., Boerwinkle, E., Bowden, D. W., Brody, J. A., Cade, B. E., Carson, A. P., Carlson, J. C., Chami, N., Chen, Y-D. I. & 31 others, Curran, J. E., de Vries, P. S., Fornage, M., Franceschini, N., Freedman, B. I., Gu, C., Heard-Costa, N. L., He, J., Hou, L., Hung, Y., Irvin, M. R., Kaplan, R. C., Kardia, S. L. R., Kelly, T., Konigsberg, I., Kooperberg, C., Kral, B. G., Li, C., Loos, Ruth, Mahaney, M. C., Martin, L. W., Mathias, R. A., Minster, R. L., Mitchell, B. D., Montasser, M. E., Morrison, A. C., Palmer, N. D., Peyser, P. A., Psaty, B. M., Raffield, L. M. & NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, N. T. F. P. M. (. C., 2023, bioRxiv, 71 p.

    Research output: Working paper › Preprint › Research

  23. Published

    In Vitro Screening for Probiotic Properties of Lactobacillus and Bifidobacterium Strains in Assays Relevant for Non-Alcoholic Fatty Liver Disease Prevention

    Lopez-Escalera, S., Lund, M. L., Hermes, G. D. A., Choi, Beatrice So-Yun, Sakamoto, Kei & Wellejus, A., 2023, In: Nutrients. 15, 10, 23 p., 2361.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Glucagon-like peptide-1 receptor agonists: role in the prevention and treatment of diabetes-related cardiovascular complications

    Lubberding, Anniek Frederike, Holst, Jens Juul & Madsbad, Sten, 2023, Cardiovascular Endocrinology and Metabolism: Theory and Practice of Cardiometabolic Medicine. Elsevier, p. 365-396

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  25. Published

    Ketolysis drives CD8+ T cell effector function through effects on histone acetylation

    Luda, K. M., Longo, J., Kitchen-Goosen, S. M., Duimstra, L. R., Ma, E. H., Watson, M. J., Oswald, B. M., Fu, Z., Madaj, Z., Kupai, A., Dickson, B. M., DeCamp, L. M., Dahabieh, M. S., Compton, S. E., Teis, R., Kaymak, I., Lau, K. H., Kelly, D. P., Puchalska, P., Williams, K. S. & 7 others, Krawczyk, C. M., Lévesque, D., Boisvert, F. M., Sheldon, R. D., Rothbart, S. B., Crawford, P. A. & Jones, R. G., 2023, In: Immunity. 56, 9, p. 2021-2035.e8 24 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Childhood Obesity at the Crossroads of Science and Social Justice

    Ludwig, D. S. & Holst, Jens Juul, 2023, In: JAMA. 329, 22, p. 1909-1910

    Research output: Contribution to journal › Editorial › Research

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