- 2020
- Published
FGF6 and FGF9 regulate UCP1 expression independent of brown adipogenesis
Shamsi, F., Xue, R., Huang, T. L., Lundh, M., Liu, Y., Leiria, L. O., Lynes, M. D., Kempf, E., Wang, C. H., Sugimoto, S., Nigro, P., Landgraf, K., Schulz, T., Li, Y., Emanuelli, B., Kothakota, S., Williams, L. T., Jessen, N., Pedersen, S. B., Böttcher, Y. & 6 others, , 2020, In: Nature Communications. 11, 1, 16 p., 1421.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic and environmental variation in educational attainment: an individual-based analysis of 28 twin cohorts
Silventoinen, K., Jelenkovic, A., Sund, R., Latvala, A., Honda, C., Inui, F., Tomizawa, R., Watanabe, M., Sakai, N., Rebato, E., Busjahn, A., Tyler, J., Hopper, J. L., Ordoñana, J. R., Sánchez-Romera, J. F., Colodro-Conde, L., Calais-Ferreira, L., Oliveira, V. C., Ferreira, P. H., Medda, E. & 55 others, , 2020, In: Scientific Reports. 10, 1, 11 p., 12681.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Distinct alterations of gut morphology and microbiota characterize accelerated diabetes onset in nonobese diabetic mice
Simon, M., Reinbeck, A. L., Wessel, C., Heindirk, J., Jelenik, T., Kaul, K., Arreguin-Cano, J., Strom, A., Blaut, M., Backhed, F., Burkart, V. & Roden, M., 2020, In: Journal of Biological Chemistry. 295, 4, p. 969-980 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of a highly controlled carbohydrate-reduced high-protein diet on markers of oxidatively generated nucleic acid modifications and inflammation in weight stable participants with type 2 diabetes: a randomized controlled trial
Skytte, M. J., Samkani, A., Astrup, A., Larsen, T. M., Frystyk, J., Poulsen, Henrik Enghusen, Henriksen, T., Holst, Jens Juul, Andersen, Ove, Madsbad, Sten, Haugaard, Steen Bendix, Krarup, T. & Larsen, E. L., 2020, In: Scandinavian Journal of Clinical & Laboratory Investigation. 80, 5, p. 401-407 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Contraction influences Per2 gene expression in skeletal muscle through a calcium-dependent pathway
Small, Lewin Barkla, Altıntaş, Ali, Laker, R. C., Ehrlich, Amy M, Pattamaprapanont, P., Villarroel, J., Pillon, N. J., Zierath, Juleen R & Barrès, Romain, 2020, In: The Journal of Physiology. 598, 24, p. 5739-5752Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GIP and the gut-bone axis – Physiological, pathophysiological and potential therapeutic implications
Stensen, S., Gasbjerg, Lærke Smidt, Helsted, M. M., Hartmann, Bolette, Christensen, Mikkel Bring & Knop, Filip Krag, 2020, In: Peptides. 125, 7 p., 170197.Research output: Contribution to journal › Review › Research › peer-review
- Published
snRNA-seq reveals a subpopulation of adipocytes that regulates thermogenesis
Sun, W., Dong, H., Balaz, M., Slyper, M., Drokhlyansky, E., Colleluori, G., Giordano, A., Kovanicova, Z., Stefanicka, P., Balazova, L., Ding, L., Husted, Anna Sofie, Rudofsky, G., Ukropec, J., Cinti, S., Schwartz, Thue W., Regev, A. & Wolfrum, C., 2020, In: Nature. 587, 31 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon Resistance at the Level of Amino Acid Turnover in Obese Subjects With Hepatic Steatosis
Suppli, M. P., Bagger, J. I., Lund, A., Demant, M., van Hall, Gerrit, Strandberg, C., Kønig, M. J., Rigbolt, K., Langhoff, J. L., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2020, In: Diabetes. 69, 6, p. 1090-1099 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals
Surendran, P., Feofanova, E. V., Lahrouchi, N., Ntalla, I., Karthikeyan, S., Cook, J., Chen, L., Mifsud, B., Yao, C., Kraja, A. T., Cartwright, J. H., Hellwege, J. N., Giri, A., Tragante, V., Thorleifsson, G., Liu, D. J., Prins, B. P., Stewart, I. D., Cabrera, C. P., Eales, J. M. & 34 others, , 2020, In: Nature Genetics. 52, 12, p. 1314-1332 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of a six-week intervention with glucagon-like peptide-1 receptor analogue on pancreatic volume, oedema and DNA synthesis in obese men
Svane, M. S., Johannesen, Helle Hjorth, Martinussen, C., Bojsen-Moller, K. N., Hansen, M. L., Hansen, A. E., Deacon, Carolyn F., Hartmann, Bolette, Keller, S. H., Loft, A., Kjær, Andreas, Madsbad, Sten, Lofgren, J., Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2020, In: Diabetologia. 63, SUPPL 1, p. S216-S217 442.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
No effects of a 6-week intervention with a glucagon-like peptide-1 receptor agonist on pancreatic volume and oedema in obese men without diabetes
Svane, M. S., Johannesen, Helle Hjorth, Martinussen, C., Bojsen-Moller, K. N., Hansen, M. L., Hansen, Adam Espe, Deacon, Carolyn F., Hartmann, Bolette, Keller, S. H., Klausen, T. L., Loft, A., Kjær, Andreas, Madsbad, Sten, Lofgren, J., Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2020, In: Diabetes, Obesity and Metabolism. 22, 10, p. 1837-1846Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Alterations in blood microbiota after colonic cancer surgery
Søby, J. H., Watt, S. K., Vogelsang, R. P., Servant, F., Lelouvier, B., Raskov, H., Knop, Filip Krag & Gögenur, Ismail, 2020, In: BJS open. 4, 6, p. 1227-1237Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Relationship between biochemical and symptomatic hypoglycemia after RYGB. Responses to a mixed meal test: a case-control study
Søeby, M., Nielsen, J. B., Pedersen, S. B., Gribsholt, S. B., Holst, Jens Juul & Richelsen, B., 2020, In: Surgery for Obesity and Related Diseases. 16, 9, p. 1179-1185 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The intestinal microbiome is a co-determinant of the postprandial plasma glucose response
Søndertoft, N. B., Vogt, J. K., Arumugam, Mani, Kristensen, M., Gøbel, R. J., Fan, Yong, Lyu, Liwei, Bahl, M. I., Eriksen, C., Ängquist, Lars, Frøkiær, Hanne, Hansen, T. H., Brix, Susanne, Nielsen, H. B., Hansen, Torben, Vestergaard, H., Gupta, R., Licht, T. R., Lauritzen, Lotte & Pedersen, Oluf Borbye, 2020, In: P L o S One. 15, 9, 23 p., e0238648.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Beating tissue factor at its own game: Design and properties of a soluble tissue factor - independent coagulation factor VIIa
Sørensen, A. B., Tuneew, I., Svensson, L. A., Persson, E., Ostergaard, H., Overgaard, M. T., Olsen, O. H. & Gandhi, P. S., 2020, In: Journal of Biological Chemistry. 295, 2, p. 517-528Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Early life body size and its associations with adult bladder cancer
Sørensen, K. K., Jensen, B. W., Thomas, P. E., Madsen, K., Eriksson, Frank, Aarestrup, J. & Baker, J. L., 2020, In: Annals of Human Biology. 47, 2, p. 166-172 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exposure to traffic noise and gestational weight gain and postpartum weight retention: a cohort study
Sørensen, M., Sørensen, Thorkild I.A., Ketzel, M. & Raaschou-Nielsen, O., 2020, In: Occupational and Environmental Medicine. 77, 2, p. 107-114 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Levels and changes in body mass index decomposed into fat and fat-free mass index: relation to long-term all-cause mortality in the general population
Sørensen, Thorkild I.A., Frederiksen, P. & Heitmann, Berit, 2020, In: International Journal of Obesity. 44, p. 2092–2100 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Activation of metabolite receptor GPR91 promotes platelet aggregation and transcellular biosynthesis of leukotriene C4
Tang, X., Fuchs, D., Tan, S., Trauelsen, Mette, Schwartz, Thue W., Wheelock, C. E., Li, N. & Haeggstrom, J. Z., 2020, In: Journal of Thrombosis and Haemostasis. 18, 4, p. 976-984 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Integration of molecular profiles in a longitudinal wellness profiling cohort
Tebani, A., Gummesson, A., Zhong, W., Koistinen, I. S., Lakshmikanth, T., Olsson, L. M., Boulund, F., Neiman, M., Stenlund, H., Hellström, C., Karlsson, M. J., Arif, M., Dodig-Crnković, T., Mardinoglu, A., Lee, S., Zhang, C., Chen, Y., Olin, A., Mikes, J., Danielsson, H. & 18 others, , 2020, In: Nature Communications. 11, 1, 14 p., 4487.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Early life body size, growth and risks of systemic lupus erythematosus: A large Danish observational cohort study
Thomas, P. E., Jensen, B. W., Sørensen, K. K., Jacobsen, Søren, Aarestrup, J. & Baker, J. L., 2020, In: Seminars in Arthritis and Rheumatism. 50, 6, p. 1507-1512 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduced carbohydrate and increased protein and fat in the diet augment the positive effect of weight loss on glucose control in type 2 diabetes patients
Thomsen, M. N., Skytte, M. J., Samkani, A., Carl, M. H., Weber, P., Astrup, A., Larsen, T. M., Frystyk, J., Holst, Jens Juul, Hartmann, Bolette, Thomsen, Henrik S., Chabanova, E., Madsbad, Sten, Haugaard, Steen Bendix & Krarup, T., 2020, In: Diabetologia. 63, Suppl. 1, p. S295-S296 614.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
The clinical effects of a carbohydrate-reduced high-protein diet on glycaemic variability in metformin-treated patients with type 2 diabetes mellitus: A randomised controlled study
Thomsen, M. N., fbg982, fbg982, Astrup, A., Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten, Krarup, T., Haugaard, Steen Bendix & Samkani, A., 2020, In: Clinical Nutrition ESPEN. 39, p. 46-52 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Outcome of concomitant treatment with thiopurines and allopurinol in patients with inflammatory bowel disease: A nationwide Danish cohort study
Thomsen, S. B., Allin, K. H., Burisch, J., Jensen, C. B., Hansen, S., Gluud, Lise Lotte, Theede, K., Kiszka-Kanowitz, M., Nielsen, A. M. & Less, T., 2020, In: European Journal of Gastroenterology and Hepatology. 8, 1, p. 68-76Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic mapping of etiologic brain cell types for obesity
Timshel, P. N., Thompson, J. J. & Pers, Tune H, 2020, In: eLife. 9, 45 p., 55851.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Leptin Serum Levels are Associated With GLP-1 Receptor Agonist-Mediated Effects on Glucose Metabolism in Clozapine-or Olanzapine-Treated, Prediabetic, Schizophrenia Patients
Tomasik, J., Rustogi, N., Larsen, J. R., Jakobsen, M. I., Svensson, C. K., Vedtofte, L., Jakobsen, M. S. L., Jespersen, H. R., Koyuncu, K., Schjerning, O., Nielsen, Jimmi, Ekstrøm, Claus Thorn, Correll, C. U., Holst, Jens Juul, Vilsbøll, Tina, Bahn, S. & Fink-Jensen, Anders, 2020, In: Schizophrenia Bulletin Open. 1, 1, 11 p., sgaa044.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabolic insights from a GHSR-A203E mutant mouse model
Pedersen, Lola Julie Torz, Osborne-Lawrence, S., Rodriguez, J., He, Z., Paula Cornejo, M., Roman Mustafa, E., Jin, C., Petersen, N., Hedegaard, M. A., Nybo, Maja Lind, Martinez Damonte, V., Metzger, N. P., Mani, B. K., Williams, K. W., Raingo, J., Perello, M., Holst, Birgitte & Zigman, J. M., 2020, In: Molecular Metabolism. 39, 16 p., 101004.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synthetic G protein-coupled bile acid receptor agonists and bile acids act via basolateral receptors in ileal and colonic mucosa
Tough, I. R., Schwartz, Thue W. & Cox, H. M., 2020, In: Neurogastroenterology and Motility. 32, 12, 14 p., e13943.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hepatic Bile Acid Reuptake in the Rat Depends on Bile Acid Conjugation but Not on Agonistic Properties towards FXR and TGR5
Trammell, Sam, Svenningsen, J. S., Holst, Jens Juul, Gillum, M. P. & Kuhre, Rune Ehrenreich, 2020, In: Molecules. 25, 14 p., 2371.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Describing the fecal metabolome in cryogenically collected samples from healthy participants
Trošt, K., Ahonen, L., Suvitaival, T., Christiansen, N., Nielsen, T., Thiele, M., Jacobsen, S., Krag, A., Rossing, Peter, Hansen, Torben, Dragsted, Lars Ove & Legido-Quigley, C., 2020, In: Scientific Reports. 10, 1, 8 p., 885.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Capturing Epidemics: Photographs by Howalt
Tybjerg, Karin, Scott-Fordsmand, Helene & Howalt, N., 2020Research output: Non-textual form › 2D/3D (psysical products) › Research
- Published
Et historisk perspektiv
Tybjerg, Karin, 2020, Personlig medicin : filosofiske og tværvidenskabelige perspektiver. Harnow Klausen, S. & Christiansen, K. (eds.). 1 ed. København: Munksgaard , p. 47-79 32 p. (Sundhed, menneske, samfund, Vol. 2).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Variation in Bile Microbiome by the Etiology of Cholestatic Liver Disease
Tyc, O., Jansen, C., Schierwagen, R., Uschner, F. E., Israelsen, M., Klein, S., Ortiz, C., Strassburg, C. P., Zeuzem, S., Gu, W., Torres, S., Praktiknjo, M., Kersting, S., Langheinrich, M., Nattermann, J., Servant, F., Arumugam, M., Krag, A., Lelouvier, B., Weismueller, T. J. & 1 others, , 2020, In: Liver Transplantation. 26, 12, p. 1652-1657 6 p.Research output: Contribution to journal › Letter › Research
- Published
One Year's Treatment with the Glucagon-Like Peptide 1 Receptor Agonist Liraglutide Decreases Hepatic Fat Content in Women with Nonalcoholic Fatty Liver Disease and Prior Gestational Diabetes Mellitus in a Randomized, Placebo-Controlled Trial
Vedtofte, L., Bahne, E., Foghsgaard, S., Bagger, J. I., Andreasen, C., Strandberg, C., Gortz, P. M., Holst, Jens Juul, Gronbaek, H., Svare, J. A., Clausen, Tine Dalsgaard, Mathiesen, Elisabeth, Damm, Peter, Gluud, Lise Lotte, Knop, Filip Krag & Vilsbøll, Tina, 2020, In: Journal of Clinical Medicine. 9, 10, 14 p., 3213.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucose-Dependent Insulinotropic Polypeptide Is a Pancreatic Polypeptide Secretagogue in Humans
Veedfald, Simon, Vedtofte, L., Skov-Jeppesen, Kirsa, Deacon, Carolyn F., Hartmann, Bolette, Vilsbøll, Tina, Knop, Filip Krag, Christensen, Mikkel Bring & Holst, Jens Juul, 2020, In: Journal of Clinical Endocrinology and Metabolism. 105, 3, p. e502-e510Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gut hormone secretion, gastric emptying and glucose absorption after frequently sampled oral glucose and liquid mixed meal tests in young men: [Meeting Abstract]
Veedfald, Simon, Rehfeld, Jens Frederik, vanHall, G., Svendsen, Lars Bo & Holst, Jens Juul, 2020, In: Neurogastroenterology and Motility. 32, SI, p. 56 1 p., 146.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Statin therapy is associated with lower prevalence of gut microbiota dysbiosis
Vieira-Silva, S., Falony, G., Belda, E., Nielsen, T., Aron-Wisnewsky, J., Chakaroun, R., Forslund, S. K., Assmann, K., Valles-Colomer, M., Nguyen, T. T. D., Proost, S., Prifti, E., Tremaroli, V., Pons, N., Le Chatelier, E., Andreelli, F., Bastard, J-P., Coelho, L. P., Galleron, N., Hansen, T. H. & 28 others, , 2020, In: Nature. 581, 7808, p. 310-315Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increase in adiposity from childhood to adulthood predicts a metabolically obese phenotype in normal-weight adults
Viitasalo, A., Pitkänen, N., Pahkala, K., Lehtimäki, T., Viikari, J. S. A., Raitakari, O. & Kilpeläinen, Tuomas O., 2020, In: International Journal of Obesity. 44, p. 848-851Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reply
Villumsen, M., Jess, T. & Allin, K. H., 2020, In: Clinical Gastroenterology and Hepatology. 18, 4, p. 1003-1004Research output: Contribution to journal › Comment/debate › Research
- Published
Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits
Vogelezang, S., Bradfield, J. P., Ahluwalia, Tarun Veer Singh, Curtin, J. A., Grarup, Niels, Schnurr, T. M., Hansen, Torben, Michaelsen, Kim F., Pedersen, Oluf Borbye, Stokholm, Jakob, Lind, M. V., Frithioff-Bøjsøe, C., Holm, Jens-Christian, Felix, J. F. & Early Growth Genetics Consortium, E. G. G. C., 2020, In: P L o S Genetics. 16, 10, 26 p., e1008718.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Polygenic and Monogenic Basis of Blood Traits and Diseases
Vuckovic, D., Bao, E. L., Akbari, P., Lareau, C. A., Mousas, A., Jiang, T., Chen, M-H., Raffield, L. M., Tardaguila, M., Huffman, J. E., Ritchie, S. C., Megy, K., Ponstingl, H., Penkett, C. J., Albers, P. K., Wigdor, E. M., Sakaue, S., Moscati, A., Manansala, R., Lo, K. S. & 31 others, , 2020, In: Cell. 182, 5, p. 1214-1231 29 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
CRISPR-engineered human brown-like adipocytes prevent diet-induced obesity and ameliorate metabolic syndrome in mice
Wang, C., Lundh, M., Fu, A., Kriszt, R., Huang, T. L., Lynes, M. D., Leiria, L. O., Shamsi, F., Darcy, J., Greenwood, B. P., Narain, N. R., Tolstikov, V., Smith, K. L., Emanuelli, Brice, Chang, Y., Hagen, S., Danial, N. N., Kiebish, M. A. & Tseng, Y., 2020, In: Science Translational Medicine. 12, 558, 15 p., eaaz8664.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Aberrant gut microbiota alters host metabolome and impacts renal failure in humans and rodents
Wang, X., Yang, S., Li, S., Zhao, L., Hao, Y., Qin, J., Zhang, L., Zhang, C., Bian, W., Zuo, L. I., Gao, X., Zhu, B., Lei, X., Gu, Z., Cui, W., Xu, X., Li, Z., Zhu, B., Li, Y., Chen, S. & 24 others, , 2020, In: Gut. 69, 12, p. 2131-2142 319766.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic Determinants of Electrocardiographic P-Wave Duration and Relation to Atrial Fibrillation
Weng, L. C., Hall, A. W., Choi, S. H., Jurgens, S. J., Haessler, J., Bihlmeyer, N. A., Grarup, N., Lin, H., Teumer, A., Li-Gao, R., Yao, J., Guo, X., Brody, J. A., Müller-Nurasyid, M., Schramm, K., Verweij, N., van den Berg, M. E., van Setten, J., Isaacs, A., Ramírez, J. & 40 others, , 2020, In: Circulation. Genomic and precision medicine. 13, 5, p. 387-395 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mind the Gut
Whiteley, Louise & Bencard, Adam, 2020, Medical Museion, University of Copenhagen.Research output: Book/Report › Book › peer-review
- Published
Tirzepatide is an imbalanced and biased dual GIP and GLP-1 receptor agonist
Willard, F. S., Douros, J. D., Gabe, M., Showalter, A. D., Wainscott, D. B., Suter, T. M., Capozzi, M. E., van der Velden, W. J. C., Stutsman, C., Cardona, G. R., Urva, S., Emmerson, P. J., Holst, Jens Juul, D'Alessio, D. A., Coghlan, M. P., Rosenkilde, Mette, Campbell, J. E. & Sloop, K. W., 2020, In: JCI insight. 5, 17, 16 p., 140532.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Skeletal muscle enhancer interactions identify genes controlling whole-body metabolism
Williams, K., Ingerslev, L. R., Bork-Jensen, J., Wohlwend, M., Hansen, Ann Normann, Small, Lewin Barkla, Ribel-Madsen, R., Astrup, A., Pedersen, Oluf Borbye, Auwerx, J., Workman, C. T., Grarup, Niels, Hansen, Torben & Barrès, Romain, 2020, In: Nature Communications. 11, 16 p., 2695.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Body mass index and risk of infections: a Mendelian randomization study of 101,447 individuals
Winter-Jensen, M., Afzal, Shoaib, Jess, T., Nordestgaard, Børge & Allin, K. H., 2020, In: European Journal of Epidemiology. 35, 4, p. 347-354Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gut microbiota profile and selected plasma metabolites in type 1 diabetes without and with stratification by albuminuria
Winther, S. A., Henriksen, P., Vogt, J. K., Hansen, T. H., Ahonen, L., Suvitaival, T., Zobel, E. H., Frimodt-Møller, M., Hansen, T. W., Hansen, Torben, Parving, H., Legido-Quigley, C., Rossing, Peter & Pedersen, Oluf Borbye, 2020, In: Diabetologia. 63, p. 2713-2724 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hepatic steatosis and glucagon resistance develope in parallel resulting in hyperglucagonaemia and hyperaminoacidaemia
Winther-Sørensen, Marie, Galsgaard, Katrine Douglas, Santos, A., Pedersen, J., Hassing, Anna Skab, Dall, M., Treebak, Jonas Thue, Kjeldsen, Sasha Alexandra Sampson, Knop, Filip Krag, Werge, M. P., Eriksen, P. L., Vilstrup, H., Gluud, Lise Lotte, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2020, In: Diabetologia. 63, SUPPL 1, p. S71-S72 142.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Glucagon acutely regulates hepatic amino acid catabolism and the effect may be disturbed by steatosis
Winther-Sørensen, M., Galsgaard, K. D., Santos, A., Trammell, S. A. J., Sulek, K., Kuhre, R. E., Pedersen, J., Andersen, D. B., Hassing, A. S., Dall, M., Treebak, J. T., Gillum, M. P., Torekov, S. S., Windeløv, J. A., Hunt, J. E., Kjeldsen, S. A. S., Jepsen, S. L., Vasilopoulou, C. G., Knop, F. K., Ørskov, C. & 7 others, , 2020, In: Molecular Metabolism. 42, 18 p., 101080.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Gut Microbiota in Prediabetes and Diabetes: A Population-Based Cross-Sectional Study
Wu, H., Tremaroli, V., Schmidt, C., Lundqvist, A., Olsson, L. M., Kramer, M., Gummesson, A., Perkins, R., Bergstrom, G. & Backhed, F., 2020, In: Cell Metabolism. 32, 3, p. 379-390.e3 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Application of tandem biotransformation for biosynthesis of new pentacyclic triterpenoid derivatives with neuroprotective effect
Xu, S., Chen, H., Fan, Yong, Xu, W. & Zhang, J., 2020, In: Bioorganic & Medicinal Chemistry Letters. 30, 4, 5 p., 126947.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
New 30-norlupane derivatives through chemical-microbial semi-synthesis of betulinic acid and their neuroprotective effect
Xu, S., Chen, H., Yang, Z., Lyu, Liwei, Fan, Yong, Sha, M., Zhang, J., Xu, W. & Lin, Y., 2020, In: Bioorganic & Medicinal Chemistry Letters. 30, 17, 127407.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In the rat pancreas, somatostatin tonically inhibits glucagon secretion and is required for glucose-induced inhibition of glucagon secretion
Xu, S. F. S., Andersen, Daniel Bjørklund, Izarzugaza, J. M. G., Kuhre, Rune Ehrenreich & Holst, Jens Juul, 2020, In: Acta Physiologica. 229, 3, 15 p., e13464.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity
Yaghootkar, H., Zhang, Y., Spracklen, C. N., Karaderi, T., Huang, L. O., Bradfield, J., Schurmann, C., Fine, R. S., Preuss, M. H., Kutalik, Z., Wittemans, L. B., Lu, Y., Metz, S., Willems, S. M., Li-Gao, R., Grarup, N., Wang, S., Molnos, S., Sandoval-Zárate, A. A., Nalls, M. A. & 32 others, , 2020, In: Diabetes. 69, 11, 93 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Anticholinergic medication exposure predicts poor physical capability: Findings from a large prospective cohort study in England
Yrjana, K. R., Keevil, V. L., Soiza, R. L., Luben, R. N., Wareham, N. J., Khaw, K. & Myint, P. K., 1 Dec 2020, In: Maturitas. 142, p. 55-63Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A community-based transcriptomics classification and nomenclature of neocortical cell types
Yuste, R., Hawrylycz, M., Aalling, N., Aguilar-valles, A., Arendt, D., Arnedillo, R. A., Ascoli, G. A., Bielza, C., Bokharaie, V., Bergmann, T. B., Bystron, I., Capogna, M., Chang, Y., Clemens, A., De Kock, C. P. J., Defelipe, J., Dos Santos, S. E., Dunville, K., Feldmeyer, D., Fiáth, R. & 53 others, , 2020, In: Nature Neuroscience. 23, p. 1456-1468 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gain-of-function mutation in the voltage-gated potassium channel gene KCNQ1 and glucose-stimulated hypoinsulinemia - case report
Zhang, J., Juhl, C. R., Hylten-Cavallius, L., Olesen, Morten Steen Salling, Linneberg, Allan René, Holst, Jens Juul, Hansen, Torben, Kanters, Jørgen K. & Torekov, Signe Sørensen, 2020, In: B M C Endocrine Disorders. 20, 5 p., 38.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mendelian randomization analysis does not support causal associations of birth weight with hypertension risk and blood pressure in adulthood
Zheng, Y., Huang, T., Wang, T., Mei, Z., Sun, Z., Zhang, T., Ellervik, C., Chai, J-F., Sim, X., van Dam, R. M., Tai, E-S., Koh, W-P., Dorajoo, R., Saw, S-M., Sabanayagam, C., Wong, T. Y., Gupta, P., Rossing, P., Ahluwalia, T. S., Vinding, R. K. & 98 others, , 2020, In: European Journal of Epidemiology. 35, p. 685–697 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of chronic silencing of relaxin-3 production in nucleus incertus neurons on food intake, body weight, anxiety-like behaviour and limbic brain activity in female rats
de Avila, C., Chometton, S., Ma, S., Pedersen, Lola Julie Torz, Timofeeva, E., Cifani, C. & Gundlach, A. L., 2020, In: Psychopharmacology. 237, 4, p. 1091-1106 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fasting- and ghrelin-induced food intake is regulated by NAMPT in the hypothalamus
de Guia, R. M., Hassing, Anna Skab, Skov, Louise Julie, Ratner, C., Plucinska, Kaja, Madsen, S., Diep, T. A., dela Cruz, Gelo, Trammell, Sam, Sustarsic, E. G., Emanuelli, Brice, Gillum, M. P., Gerhart-Hines, Zach, Holst, Birgitte & Treebak, Jonas Thue, 2020, In: Acta Physiologica. 228, 4Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multi-omics characterization of a diet-induced obese model of non-alcoholic steatohepatitis
Ægidius, H. M., Veidal, S. S., Feigh, M., Hallenborg, P., Puglia, M., Pers, Tune H, Vrang, N., Jelsing, J., Kornum, Birgitte Rahbek, Blagoev, B. & Rigbolt, K. T. G., 2020, In: Scientific Reports. 10, 1, 12 p., 1148.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evidence for Relationship Between Early Dumping and Postprandial Hypoglycemia After Roux-en-Y Gastric Bypass
Øhrstrøm, C. C., Worm, Dorte, Kielgast, U. L., Holst, Jens Juul & Hansen, D. L., 2020, In: Obesity Surgery. 30, 3, p. 1038-1045Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories: a pooled analysis of 2181 population-based studies with 65 million participants
NCD Risk Factor Collaboration (NCD-RisC), N. R. F. C. (., Afzal, Shoaib, Michaelsen, Kim F., Damsgaard, Camilla Trab, Sørensen, Thorkild I.A. & Ängquist, Lars, 2020, In: Lancet. 396, 10261, p. 1511-1524 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Birthweight and risk of thyroid cancer and its histological types: A large cohort study
Aarestrup, J., Kitahara, C. M. & Baker, J. L., 2019, In: Cancer Epidemiology. 62, 101564.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cardiovascular Risk Profile Among Patients With Inflammatory Bowel Disease: A Population-based Study of More Than 100 000 Individuals
Aarestrup, J., Jess, T., Kobylecki, C. J., Nordestgaard, Børge & Allin, K. H., 2019, In: Journal of Crohn's and Colitis. 13, 3, p. 319-323 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Childhood Overweight, Tallness, and Growth Increase Risks of Ovarian Cancer
Aarestrup, J., Trabert, B., Ulrich, L. G., Wentzensen, N., Sørensen, Thorkild I.A. & Baker, J. L., 2019, In: Cancer Epidemiology, Biomarkers & Prevention. 28, 1, p. 183-188Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic Determinants of Weight Loss After Bariatric Surgery
Aasbrenn, M., Schnurr, T. M., Have, C. T., Svendstrup, M., Hansen, D. L., Worm, Dorte, Balslev-Harder, M., Hollensted, M., Grarup, Niels, Burgdorf, K. S., drb459, drb459, Pedersen, Oluf Borbye, Sørensen, Thorkild I.A., Fenger, M., Madsbad, Sten & Hansen, Torben, 2019, In: Obesity Surgery. 29, 8, p. 2554-2561 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The antidepressant-like effect of probiotics and their faecal abundance may be modulated by the cohabiting gut microbiota in rats
Abildgaard, A., Kern, T., Pedersen, Oluf Borbye, Hansen, Torben, Wegener, G. & Lund, S., 2019, In: European Neuropsychopharmacology. 29, 1, p. 98-110Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Levels and Changes in Childhood Body Mass Index in Relation to Risk of Atrial Fibrillation and Atrial Flutter in Adulthood
Adelborg, K., Ängquist, Lars, Ording, A., Gjærde, L. K., Bjerregaard, L. G., Sørensen, H. T., Sørensen, Thorkild I.A. & Baker, J. L., 2019, In: American Journal of Epidemiology. 188, 4, p. 684-693 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Unge forskere: S-løftebrud er en katastrofe for universiteterne
Aguirre, V., Andersen, C., Andersen, P. R., Bjørk, R., Clemmensen, C., Dalsgaard, P., Danbolt, M., Dimke, H., Engberg-Pedersen, A., Feliu, E., Jauffred, L., Jønsson, K., Kornum, B. R., Kropp, K., Laustsen, A., Levisen, C., Lock, N., Lomborg, S., Møller, N. M., Niss, K. & 5 others, , 2019Research output: Other contribution › Communication
- Published
A novel rare CUBN variant and three additional genes identified in Europeans with and without diabetes: results from an exome-wide association study of albuminuria
Ahluwalia, T. S., Schulz, C-A., Waage, J., Skaaby, T., Sandholm, N., van Zuydam, N., Charmet, R., Bork-Jensen, J., Almgren, P., Thuesen, B. H., Bedin, M., Brandslund, I., Christensen, C. K., Linneberg, A., Ahlqvist, E., Groop, P-H., Hadjadj, S., Tregouet, D-A., Jorgensen, M. E., Grarup, N. & 9 others, , 2019, In: Diabetologia. 62, 2, p. 292-305Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Editorial: Novel biomarkers for type 2 diabetes
Ahluwalia, T. S., Kilpeläinen, Tuomas O., Singh, S. & Rossing, Peter, 1 Sep 2019, In: Frontiers in Endocrinology. 10, p. 1-3 3 p., 649.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Compartmentalization of Immune Response and Microbial Translocation in Decompensated Cirrhosis
Alvarez Silva, Maria Camila, Schierwagen, R., Pohlmann, A., Magdaleno, F., Uschner, F. E., Ryan, P., Vehreschild, M. J. G. T., Claria, J., Latz, E., Lelouvier, B., Arumugam, Mani & Trebicka, J., 2019, In: Frontiers in Immunology. 10, 11 p., 69.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Environmental factors influence the epigenetic signature of newborns from mothers with gestational diabetes
Andersen, E., Altıntaş, Ali, Andersson-Hall, U., Holmäng, A. & Barrès, Romain, 2019, In: Epigenomics. 11, 8, p. 861-873 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preadipocytes from obese humans with type 2 diabetes are epigenetically reprogrammed at genes controlling adipose tissue function
Andersen, E., Ingerslev, L. R., Fabre, O., Donkin, I., Altıntaş, Ali, Versteyhe, S., Bisgaard, T., Kristiansen, V. B., Simar, D. & Barrès, Romain, 2019, In: International Journal of Obesity. 43, 2, p. 306-318 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of weight-loss management on children and adolescents with obesity and obstructive sleep apnea
Andersen, I. G., Holm, Jens-Christian & Homøe, Preben, 2019, In: International Journal of Pediatric Otorhinolaryngology. 123, p. 57-62Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Obstructive sleep apnea in children and adolescents with and without obesity
Andersen, I. G., Holm, Jens-Christian & Homøe, Preben, 2019, In: European Archives of Oto-Rhino-Laryngology. 276, 3, p. 871-878Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetics of Latent Autoimmune Diabetes in Adults
Lepola, Mette Andersen & Hansen, Torben, 2019, In: Current Diabetes Reviews. 15, 3, p. 194-198 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hidradenitis suppurativa in a cohort of children and adolescents with overweight and obesity
Andersen, P. L., Kromann, C., Fonvig, Cilius Esmann, Riis, P. T., Holm, J. -. & Jemec, Gregor, 2019, In: Experimental Dermatology. 28, S2, p. 37-38 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Microbial evolutionary medicine: from theory to clinical practice
Andersen, Sandra Breum, Shapiro, B. J., Vandenbroucke-Grauls, C. & de Vos, M. G. J., 2019, In: Lancet Infectious Diseases. 19, 8, p. e273-e283 11 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Association between topical corticosteroid use and type 2 diabetes in two European population-based adult cohorts
Andersen, Y. M. F., Egeberg, A., Ban, L., Gran, S., Williams, H. C., Francis, N. A., Knop, Filip Krag, Gislason, Gunnar Hilmar, Skov, Lone & Thyssen, Jacob Pontoppidan, 2019, In: Diabetes Care. 42, 6, p. 1095-1103Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of genetic variants previously implicated in coronary artery disease with age at onset of coronary artery disease requiring revascularizations
Andersson, C., Krogager, M. L., Skals, R. K., Appel, E. V. R., Have, C. T., Grarup, N., Pedersen, O., Jeppesen, J. L., Pedersen, O. D., Dominguez, H., Dixen, U., Engstrøm, T., Tønder, N., Roden, D. M., Stender, S., Gislason, G. H., Enghusen-Poulsen, H., Hansen, T., Køber, L., Torp-Pedersen, C. & 1 others, , 2019, In: P L o S One. 14, 2, 12 p., e0211690.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Liraglutide improves the beta-cell function without increasing insulin secretion during a mixed meal in patients, who exhibit well-controlled type 2 diabetes and coronary artery disease
Anholm, C., Kumarathurai, P., Jurs, A., Pedersen, L. R., Nielsen, Olav Wendelboe, Kristiansen, O. P., Fenger, M., Holst, Jens Juul, Madsbad, Sten, Sajadieh, Ahmad & Haugaard, Steen Bendix, 2019, In: Diabetology & Metabolic Syndrome. 11, 12 p., 42.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hybrid Encounters in the arts and sciences. A dialogue
Arends, B., Arnold, Ken, Greinke, B., Hauser, Jens, Horstmann, N. (ed.) & Landbrecht, C. (ed.), 2019, Berlin: Ernst Schering Foundation. 36 p. (Hybrid Encounters Publication).Research output: Book/Report › Book
- Published
A house of collaboration: investigating the intersections of art and biomedicine
Arnold, Ken, Bencard, Adam, Pedersen, B. V., Söderqvist, Thomas, Tybjerg, Karin & Whiteley, Louise, 2019, Art and Science in Museums. Rossi-Linnemann, C. & di Martini, G. (eds.). 1 ed. Routledge, (Routledge Research in Museum Studies).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Microbial fermentation of flaxseed fibers modulates the transcriptome of GPR41-expressing enteroendocrine cells and protects mice against diet-induced obesity
Arora, Tulika, Rudenko, Olga, Egerod, Kristoffer Lihme, Husted, Anna Sofie, Kovatcheva-Datchary, P., Akrami, R., Kristensen, M., Schwartz, Thue W. & Backhed, F., Mar 2019, In: American Journal of Physiology: Endocrinology and Metabolism. 316, 3, p. E453-E463Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Extracellular Fluid Volume Expansion Uncovers a Natriuretic Action of GLP-1: A Functional GLP-1–Renal Axis in Man
Asmar, A., Cramon, P. K., Simonsen, L., Asmar, M., Sorensen, Charlotte Mehlin, Madsbad, Sten, Moro, C., Hartmann, Bolette, Jensen, B. L., Holst, Jens Juul & Bülow, J., Jul 2019, In: The Journal of clinical endocrinology and metabolism. 104, 7, p. 2509–2519Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GIP-induced vasodilation in human adipose tissue involves capillary recruitment
Asmar, M., Asmar, A., Simonsen, L., Dela, Flemming, Holst, Jens Juul & Bulow, J., Jun 2019, In: Endocrine Connections. 8, 6, p. 806-813Research output: Contribution to journal › Journal article › Research › peer-review
- Published
RETRACTION: Glucose-Dependent Insulinotropic Polypeptide Increases Blood Flow in Adipose Tissue of Humans by Recruiting Capillaries (Retraction of Vol 104, Pg 16, 2019)
Asmar, M., Asmar, A., Simonsen, L., Holst, Jens Juul & Bulow, J., 2019, In: Journal of Clinical Endocrinology & Metabolism. 104, 1, p. W1-W9Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Application of unsupervised learning in weight-loss categorisation for weight management programs
Babajide, O., Hissam, T., Palczewska, A., Astrup, A., Martinez, J. A., Oppert, J. M. & Sørensen, Thorkild I.A., 2019, The 10th IEEE International Conference on Dependable Systems, Services and Technologies. DESSERT'2019: Conference proceedings. IEEE, p. 94-101 8 p. 8770032Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
- Published
Functional Magnetic Resonance Imaging (fMRI) of Neural Responses to Visual and Auditory Food Stimuli Pre and Post Roux-en-Y Gastric Bypass (RYGB) and Sleeve Gastrectomy (SG)
Baboumian, S., Pantazatos, S. P., Kothari, S., McGinty, J., Holst, Jens Juul & Geliebter, A., 2019, In: Neuroscience. 409, p. 290-298Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Shining light on microbial signaling to distant organs
Backhed, F., 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 16, p. 7617-7619Research output: Contribution to journal › Comment/debate › Research
- Published
The next decade of metabolism
Backhed, F., Bugianesi, E., Christofk, H., Dikic, I., Gupta, R., Mair, W. B., O'Neill, L. A. J., Ralser, M., Sabatini, D. M. & Tschop, M., 2019, In: Nature Metabolism. 1, p. 2-4Research output: Contribution to journal › Comment/debate › Research
- Published
Increased Body Weight and Fat Mass After Subchronic GIP Receptor Antagonist, but Not GLP-2 Receptor Antagonist, Administration in Rats
Baidassano, S., Gasbjerg, Lærke Smidt, Kizilkaya, Hüsün Sheyma, Rosenkilde, Mette, Holst, Jens Juul & Hartmann, Bolette, 2019, In: Frontiers in Endocrinology. 10, 11 p., 492.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Paternal high-fat diet transgenerationally impacts hepatic immunometabolism
Barbosa, T. D. C., Alm, P. S., Krook, A., Barrès, Romain & Zierath, Juleen R, 2019, In: FASEB Journal. 33, 5, p. 6269-6280Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protein aggregation capture on microparticles enables multi-purpose proteomics sample preparation
Batth, Tanveer Singh, Tollenaere, M. A. X., Rüther, P. L., Gonzalez-Franquesa, A., Prabhakar, B. S., Bekker-Jensen, Simon Holst, Deshmukh, Atul Shahaji & Olsen, Jesper Velgaard, 2019, In: Molecular and Cellular Proteomics. 18, 5, p. 1027-1035Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Combined GLP-1, Oxyntomodulin, and Peptide YY Improves Body Weight and Glycemia in Obesity and Prediabetes/Type 2 Diabetes: A Randomized Single-Blinded Placebo Controlled Study
Behary, P., Tharakan, G., Alexiadou, K., Johnson, N., Albrechtsen, N. J. W., Kenkre, J., Cuenco, J., Hope, D., Anyiam, O., Choudhury, S., Alessimii, H., Poddar, A., Minnion, J., Doyle, C., Frost, G., Le Roux, C., Purkayastha, S., Moorthy, K., Dhillo, W., Holst, J. J. & 4 others, , 2019, In: Diabetes Care. 42, 7, 8 p., dc190449.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Curating experimental entanglements
Bencard, Adam, Whiteley, Louise & Thon, C. H., 2019, Curatorial Challenges: Interdisciplinary Perspectives on Contemporary Curating. Hansen, M. V., Henningsen, A. F. & Gregersen, A. (eds.). 1 ed. Routledge, (Routledge research in art museums and exhibitions).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity
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Determinants of plasma levels of proglucagon and the metabolic impact of glucagon receptor signalling: a UK Biobank study
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Targeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment
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mTORC1 controls murine postprandial hepatic glycogen synthesis via Ppp1r3b
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