Novo Nordisk Foundation Center for Basic Metabolic Research

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  1. 2009
  2. Published

    Validation of a multimarker model for assessing risk of type 2 diabetes from a five-year prospective study of 6784 Danish people (Inter99)

    Urdea, M., Kolberg, J., Wilber, J., Gerwien, R., Moler, E., Rowe, M., Jorgensen, P., Hansen, T., Pedersen, Oluf Borbye, Jørgensen, T. & Borch-Johnsen, K., 2009, In: Journal of Diabetes Science and Technology. 3, 4, p. 748-55 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Bleeding peptic ulcer. Prevalence of Helicobacter pylori and use of nonsteroidal anti-inflammatory drugs/acetylsalicylic acid

    Vestergard, A., Bredahl, K., Muckadell, O. B. D., Pedersen, Oluf Borbye & Hansen, J. M., 2009, In: Ugeskrift for læger. 171, 4, p. 235-239 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Impaired Insulin-Mediated Phosphorylation of Skeletal Muscle TBC1D4 at Multiple Sites in Type 2 Diabetes. Effect of Endurance Training on TBC1D4 Protein and Phosphorylation

    Vind, B. F., Pehmoller, C., Treebak, Jonas Thue, Birk, Jesper Bratz, Hey-Mogensen, M., Beck-Nielsen, H., Wojtaszewski, Jørgen F P & Hojlund, K., 2009, In: Diabetes.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Fatness-associated FTO gene variant increases mortality independent of fatness--in cohorts of Danish men

    Zimmermann, E., Kring, S. I. I., Berentzen, T. L., Holst, C., Pers, T. H., Hansen, Torben, Pedersen, Oluf Borbye, Sørensen, Thorkild I.A. & Jess, T., 2009, In: PLoS ONE. 4, 2, p. e4428

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Variation in the gene encoding Kruppel-like factor 7 influences body fat: studies of 14,818 Danes

    Zobel, D., Andreasen, C., Burgdorf, K., Andersson, E., Sandbæk, A., Lauritzen, T., Borch-Johnsen, K., Jørgensen, T., Maeda, S., Nakamura, Y., Eiberg, Hans Rudolf Lytchoff, Pedersen, Oluf Borbye & Hansen, Torben, 2009, In: European Journal of Endocrinology. 160, 4, p. 603-9

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Variants near MC4R associate with obesity and influence obesity-related quantitative traits in a population of middle-aged people: studies of 14,940 Danes

    Zobel, D. P., Andreasen, C. H., Grarup, N., Eiberg, Hans Rudolf Lytchoff, Sørensen, Thorkild I.A., Sandbæk, A., Lauritzen, T., Borch-Johnsen, K., Jørgensen, T., Pedersen, Oluf Borbye & Hansen, T., 2009, In: Diabetes. p. 757-764 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. 2008
  9. Published

    Endothelial nitric oxide synthase gene haplotypes and diabetic nephropathy among Asian Indians

    Ahluwalia, Tarun Veer Singh, Ahuja, M., Rai, T. S., Kohli, H. S., Sud, K., Bhansali, A. & Khullar, M., Jul 2008, In: Molecular and Cellular Biochemistry. 314, 1-2, p. 9-17 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Functional ontogeny of the proglucagon-derived peptide axis in the premature human neonate

    Amin, H., Holst, Jens Juul, Hartmann, Bolette, Wallace, L., Wright, J. & Sigalet, D. L., Jan 2008, In: Pediatrics. 121, 1, p. e180-6

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    AHSG tag single nucleotide polymorphisms associate with type 2 diabetes and dyslipidemia: studies of metabolic traits in 7,683 white Danish subjects

    Andersen, G., Burgdorf, K. S., Sparsø, T., Borch-Johnsen, K., Jørgensen, T., Hansen, T. & Pedersen, Oluf Borbye, 2008, In: Diabetes. 57, 5, p. 1427-32 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Low physical activity accentuates the effect of the FTO rs9939609 polymorphism on body fat accumulation

    Andreasen, C. H., Stender-Petersen, K. L., Mogensen, M. S., Torekov, Signe Sørensen, Wegner, L., Andersen, G., Nielsen, A. L., Albrechtsen, Anders, Borch-Johnsen, K., Rasmussen, S. S., Clausen, J. O., Sandbaek, A., Lauritzen, T., Hansen, L., Jørgensen, T., Pedersen, Oluf Borbye & Hansen, T., 2008, In: Diabetes. 57, 1, p. 95-101 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Lack of association between PKLR rs3020781 and NOS1AP rs7538490 and type 2 diabetes, overweight, obesity and related metabolic phenotypes in a Danish large-scale study: case-control studies and analyses of quantitative traits

    Andreasen, C. H., Mogensen, M. S., Borch-Johnsen, K., Sandbæk, A., Lauritzen, T., Almind, K., Pedersen, Oluf Borbye, Hansen, L., Jørgensen, T. & Hansen, Torben, 2008, In: BMC Medical Genetics. 9, p. 118

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Common nonsynonymous variants in PCSK1 confer risk of obesity.

    Benzinou, M., Creemers, J. W. M., Choquet, H., Lobbens, S., Dina, C., Durand, E., Guerardel, A., Boutin, P., Jouret, B., Heude, B., Balkau, B., Tichet, J., Marre, M., Potoczna, N., Horber, F., Le Stunff, C., Czernichow, S., Sandbæk, A., Lauritzen, T., Borch-Johnsen, K. & 12 others, Andersen, G., Kiess, W., Körner, A., Kovacs, P., Jacobson, P., Carlsson, L. M. S., Walley, A. J., Jørgensen, T., Hansen, Torben, Pedersen, Oluf Borbye, Meyre, D. & Froguel, P., 2008, In: Nature Genetics. 40, 8, p. 943-5 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Endocannabinoid receptor 1 gene variations increase risk for obesity and modulate body mass index in European populations

    Benzinou, M., Chèvre, J., Ward, K. J., Lecoeur, C., Dina, C., Lobbens, S., Durand, E., Delplanque, J., Horber, F. F., Heude, B., Balkau, B., Borch-Johnsen, K., Jørgensen, T., Hansen, T., Pedersen, Oluf Borbye, Meyre, D. & Froguel, P., 2008, In: Human Molecular Genetics. 17, 13, p. 1916-21 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Lack of association of fatness-related FTO gene variants with energy expenditure or physical activity

    Berentzen, T., Kring, S. I. I., Holst, C., Zimmermann, E., Jess, T., Hansen, T., Pedersen, Oluf Borbye, Toubro, S., Astrup, A. & Sørensen, Thorkild I.A., 2008, In: Journal of Clinical Endocrinology and Metabolism. 93, 7, p. 2904-2908 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    The common SLC30A8 Arg325Trp variant is associated with reduced first-phase insulin release in 846 non-diabetic offspring of type 2 diabetes patients--the EUGENE2 study

    Boesgaard, T. W., Zilinskaite, J., Vänttinen, M., Laakso, M., Jansson, P., Hammarstedt, A., Smith, U., Stefan, N., Fritsche, A., Häring, H., Hribal, M., Sesti, G., Zobel, D. P., Pedersen, Oluf Borbye, Hansen, Torben & EUGENE 2 Consortium, E. 2. C., 2008, In: Diabetologia. 51, 5, p. 816-20 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels

    Chen, W-M., Erdos, M. R., Jackson, A. U., Saxena, R., Sanna, S., Silver, K. D., Timpson, N. J., Hansen, T., Orrù, M., Grazia Piras, M., Bonnycastle, L. L., Willer, C. J., Lyssenko, V., Shen, H., Kuusisto, J., Ebrahim, S., Sestu, N., Duren, W. L., Spada, M. C., Stringham, H. M. & 31 others, Scott, L. J., Olla, N., Swift, A. J., Najjar, S., Mitchell, B. D., Lawlor, D. A., Smith, G. D., Ben-Shlomo, Y., Andersen, G., Borch-Johnsen, K., Jørgensen, T., Saramies, J., Valle, T. T., Buchanan, T. A., Shuldiner, A. R., Lakatta, E., Bergman, R. N., Uda, M., Tuomilehto, J., Pedersen, Oluf Borbye, Cao, A., Groop, L., Mohlke, K. L., Laakso, M., Schlessinger, D., Collins, F. S., Altshuler, D., Abecasis, G. R., Boehnke, M., Scuteri, A. & Watanabe, R. M., 2008, In: Journal of Clinical Investigation. 118, 7, p. 2620-8 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Insulinoma in a third-trimester pregnant woman combined with pre-eclampsia: a case report and review of the diagnostic strategies

    Christiansen, P. E. & drb459, drb459, Jul 2008, In: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology. 24, 7, p. 417-22 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    High prevalence of type 2 diabetes and pre-diabetes in adult offspring of women with gestational diabetes mellitus or type 1 diabetes: the role of intrauterine hyperglycemia

    Clausen, Tine Dalsgaard, Mathiesen, E. R., Hansen, T., Pedersen, Oluf Borbye, Jensen, D. M., Lauenborg, J., Damm, Peter, Clausen, T. D., Mathiesen, Elisabeth, Hansen, T., Pedersen, O., Jensen, D., Lauenborg, J. & Damm, Peter, 1 Feb 2008, In: Diabetes Care. 31, 2, p. 340-6 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Seven mutations in the human insulin gene linked to permanent neonatal/infancy-onset diabetes mellitus

    Colombo, C., Porzio, O., Liu, M., Massa, O., Vasta, M., Salardi, S., Beccaria, L., Monciotti, C., Toni, S., Pedersen, Oluf Borbye, Hansen, T., Federici, L., Pesavento, R., Cadario, F., Federici, G., Ghirri, P., Arvan, P., Iafusco, D., Barbetti, F. & Early Onset Diabetes Study Group of the Italian Society of Pediatric Endocrinology and Diabetes (SIEDP), E. O. D. S. G. O. T. I. S. O. P. E. A. D. (., 2008, In: Journal of Clinical Investigation. 118, 6, p. 2148-56 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Overexpression of the dual-specificity phosphatase MKP-4/DUSP-9 protects against stress-induced insulin resistance

    Emanuelli, Brice, Eberlé, D., Suzuki, R. & Kahn, C. R., 4 Mar 2008, In: Proceedings of the National Academy of Sciences of the United States of America. 105, 9, p. 3545-50 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    SOCS-1 deficiency does not prevent diet-induced insulin resistance

    Emanuelli, Brice, Macotela, Y., Boucher, J. & Ronald Kahn, C., 12 Dec 2008, In: Biochemical and Biophysical Research Communications. 377, 2, p. 447-52 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Impaired fasting glycaemia vs impaired glucose tolerance: similar impairment of pancreatic alpha and beta cell function but differential roles of incretin hormones and insulin action

    Faerch, K., Vaag, Allan, Holst, Jens Juul, Glümer, C., Pedersen, Oluf Borbye & Borch-Johnsen, K., 2008, In: Diabetologia. 51, 5, p. 853-61 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Variance of the SGK1 gene is associated with insulin secretion in different European populations: results from the TUEF, EUGENE2, and METSIM studies.

    Friedrich, B., Weyrich, P., Stancáková, A., Wang, J., Kuusisto, J., Laakso, M., Sesti, G., Succurro, E., Smith, U., Hansen, Torben, Pedersen, Oluf Borbye, Machicao, F., Schäfer, S., Lang, F., Risler, T., Ullrich, S., Stefan, N., Fritsche, A. & Häring, H., 2008, In: PLoS ONE. 3, 11, p. e3506

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Multifactorial intervention and mortallity in type 2 diabetes- Reply

    Gaede, P., Parving, H. & Pedersen, Oluf Borbye, 2008, In: New England Journal of Medicine. p. 358: 2292-2293

    Research output: Contribution to journal › Comment/debate › Research

  27. Published

    Cost-effectiveness of intensified versus conventional multifactorial intervention in type 2 diabetes: results and projections from the Steno-2 study

    Gaede, P., Valentine, W. J., Palmer, A. J., Tucker, D. M. D., Lammert, M., Parving, H. & Pedersen, Oluf Borbye, 2008, In: Diabetes Care. 31, 8, p. 1510-5 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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