Novo Nordisk Foundation Center for Basic Metabolic Research

  1. 2008
  2. Published

    Clinical risk factors, DNA variants, and the development of type 2 diabetes

    Lyssenko, V., Jonsson, Anna Elisabet, Almgren, P., Pulizzi, N., Isomaa, B., Tuomi, T., Berglund, G., Altshuler, D., Nilsson, P. & Groop, L., 20 Nov 2008, In: New England Journal of Medicine. 359, 21, p. 2220-32 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Oxidative stress in primary glomerular diseases: a comparative study

    Markan, S., Kohli, H. S., Sud, K., Ahuja, M., Ahluwalia, Tarun Veer Singh, Sakhuja, V. & Khullar, M., Apr 2008, In: Molecular and Cellular Biochemistry. 311, 1-2, p. 105-10 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    The KCNMB1 Glu65Lys polymorphism associates with reduced systolic and diastolic blood pressure in the Inter99 study of 5729 Danes.

    Nielsen, T., Burgdorf, K. S., Grarup, N., Borch-Johnsen, K., Hansen, T., Jørgensen, T., Pedersen, Oluf Borbye & Andersen, G., 2008, In: Journal of Hypertension. 26, 11, p. 2142-6 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Genetic and environmental effects on mortality before age 70 years

    Petersen, L., Andersen, Per Kragh, Sørensen, Thorkild I.A., Petersen, L., Andersen, P. K. & Sørensen, Thorkild I.A., 1 May 2008, In: Epidemiology. 19, 3, p. 472-6 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    ACE I/D polymorphism in Indian patients with hypertrophic cardiomyopathy and dilated cardiomyopathy

    Rai, T. S., Dhandapany, P. S., Ahluwalia, Tarun Veer Singh, Bhardwaj, M., Bahl, A., Talwar, K. K., Nair, K., Rathinavel, A. & Khullar, M., Apr 2008, In: Molecular and Cellular Biochemistry. 311, 1-2, p. 67-72 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Metabolic adaptations through the PGC-1α and SIRT1 pathways

    Rodgers, J. T., Lerin, C., Gerhart-Hines, Zach & Puigserver, P., 9 Jan 2008, In: FEBS Letters. 582, 1, p. 46-53 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Non-replication of genome-wide based associations between common variants in INSIG2 and PFKP and obesity in studies of 18,014 Danes

    Sandholt, C. H., Mogensen, M. S., Borch-Johnsen, K., Sandbaek, A., Lauritzen, T., Sørensen, Thorkild I.A., Hansen, L., Almind, K., Jørgensen, T., Pedersen, Oluf Borbye & Hansen, Torben, 2008, In: PLoS ONE. 3, 8, p. e2872 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    The search for putative unifying genetic factors for components of the metabolic syndrome

    Sjögren, M., Lyssenko, V., Jonsson, Anna Elisabet, Berglund, G., Nilsson, P., Groop, L. & Orho-Melander, M., Dec 2008, In: Diabetologia. 51, 12, p. 2242-51 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Impact of polymorphisms in WFS1 on prediabetic phenotypes in a population-based sample of middle-aged people with normal and abnormal glucose regulation

    Sparsø, T., Andersen, G., Albrechtsen, Anders, Jørgensen, T., Borch-Johnsen, K., Sandbaek, A., Lauritzen, T., Wasson, J., Permutt, M. A., Glaser, B., Madsbad, Sten, Pedersen, Oluf Borbye & Hansen, Torben, 2008, In: Diabetologia. 51, 9, p. 1646-52 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    A candidate type 2 diabetes polymorphism near the HHEX locus affects acute glucose-stimulated insulin release in European populations: results from the EUGENE2 study

    Staiger, H., Stancáková, A., Zilinskaite, J., Vänttinen, M., Hansen, T., Marini, M. A., Hammarstedt, A., Jansson, P., Sesti, G., Smith, U., Pedersen, Oluf Borbye, Laakso, M., Stefan, N., Fritsche, A. & Häring, H., 2008, In: Diabetes. 57, 2, p. 514-7 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Single-nucleotide polymorphism rs7754840 of CDKAL1 is associated with impaired insulin secretion in nondiabetic offspring of type 2 diabetic subjects and in a large sample of men with normal glucose tolerance

    Stancáková, A., Pihlajamäki, J., Kuusisto, J., Stefan, N., Fritsche, A., Häring, H., Andreozzi, F., Succurro, E., Sesti, G., Boesgaard, T. W., Hansen, T., Pedersen, Oluf Borbye, Jansson, P. A., Hammarstedt, A., Smith, U., Laakso, M. & EUGENE2 Consortium, E. C., 2008, In: Journal of Clinical Endocrinology and Metabolism. 93, 5, p. 1924-30 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Possible role of AS160 in post-exercise increased insulin sensitivity in human skeletal muscle

    Treebak, Jonas Thue, Kristensen, Jonas Møller, Frosig, C., Pehmoller, C., Hardie, D. G., Kiens, Bente, Richter, Erik A. & Wojtaszewski, Jørgen F P, 2008, In: Diabetes.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations.

    Unoki, H., Takahashi, A., Kawaguchi, T., Hara, K., Horikoshi, M., Andersen, G., Ng, D. P. K., Holmkvist, J., Borch-Johnsen, K., Jørgensen, T., Sandbæk, A., Lauritzen, T., Hansen, T., Nurbaya, S., Tsunoda, T., Kubo, M., Babazono, T., Hirose, H., Hayashi, M., Iwamoto, Y. & 10 others, Kashiwagi, A., Kaku, K., Kawamori, R., Tai, E. S., Pedersen, Oluf Borbye, Kamatani, N., Kadowaki, T., Kikkawa, R., Nakamura, Y. & Maeda, S., 2008, In: Nature Genetics. 40, 9, p. 1098-1102 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    The Gly482Ser genotype at the PPARGC1A gene and elevated blood pressure: a meta-analysis involving 13,949 individuals

    Vimaleswaran, K. S., Luan, J., Andersen, G., Muller, Y. L., Wheeler, E., Brito, E. C., O'Rahilly, S., Pedersen, Oluf Borbye, Baier, L. J., Knowler, W. C., Barroso, I., Wareham, N. J., Loos, R. J. F. & Franks, P. W., 2008, In: Journal of Applied Physiology. 105, 4, p. 1352-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Impact of TCF7L2 rs7903146 on insulin secretion and action in young and elderly Danish twins.

    Wegner, L., Hussain, M. S., Pilgaard, K., Hansen, T., Pedersen, Oluf Borbye, Vaag, Allan & Poulsen, I. P., 2008, In: Journal of Clinical Endocrinology and Metabolism. 93, 10, p. 4013-9 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Implicit knowledge of visual uncertainty guides decisions with asymmetric outcomes

    Whiteley, Louise & Sahani, M., 2008, In: Journal of Vision. 8, 3, p. 2.1-15

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Uncertainty, reward, and attention in the Bayesian brain

    Whiteley, Louise, 2008

    Research output: Book/ReportPh.D. thesis

  19. Published

    Visual processing and the bodily self

    Whiteley, Louise, Spence, C. & Haggard, P., 2008, In: Acta Psychologica. 127, 1, p. 129-36 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus

    Yasuda, K., Miyake, K., Horikawa, Y., Hara, K., Osawa, H., Furuta, H., Hirota, Y., Mori, H., Jonsson, A. E., Sato, Y., Yamagata, K., Hinokio, Y., Wang, H-Y., Tanahashi, T., Nakamura, N., Oka, Y., Iwasaki, N., Iwamoto, Y., Yamada, Y., Seino, Y. & 27 others, Maegawa, H., Kashiwagi, A., Takeda, J., Maeda, E., Shin, H. D., Cho, Y. M., Park, K. S., Lee, H. K., Ng, M. C. Y., Ma, R. C. W., So, W., Chan, J. C. N., Lyssenko, V., Tuomi, T., Nilsson, P., Groop, L., Kamatani, N., Sekine, A., Nakamura, Y., Yamamoto, K., Yoshida, T., Tokunaga, K., Itakura, M., Makino, H., Nanjo, K., Kadowaki, T. & Kasuga, M., Sep 2008, In: Nature Genetics. 40, 9, p. 1092-7 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

    Zeggini, E., Scott, L. J., Saxena, R., Voight, B. F., Marchini, J. L., Hu, T., de Bakker, P. I. W., Abecasis, G. R., Almgren, P., Andersen, G., Ardlie, K., Boström, K. B., Bergman, R. N., Bonnycastle, L. L., Borch-Johnsen, K., Burtt, N. P., Chen, H., Chines, P. S., Daly, M. J., Deodhar, P. & 31 others, Ding, C., Doney, A. S. F., Duren, W. L., Elliott, K. S., Erdos, M. R., Frayling, T. M., Freathy, R. M., Gianniny, L., Grallert, H., Grarup, N., Groves, C. J., Guiducci, C., Hansen, Torben, Herder, C., Hitman, G. A., Hughes, T. E., Isomaa, B., Jackson, A. U., Jørgensen, T., Kong, A., Kubalanza, K., Kuruvilla, F. G., Kuusisto, J., Langenberg, C., Lango, H., Lauritzen, T., Li, Y., Lindgren, C. M., Lyssenko, V., Wellcome Trust Case Control Consortium, W. T. C. C. C. & Pedersen, Oluf Borbye, 2008, In: Nature Genetics. 40, 5, p. 638-45 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    A Somewhat Subjective Introduction to Gene Mapping through Nonparametric Linkage Analysis

    Ängquist, Lars, 2008, Genetic Recombination Research Progress. Schultz, J. H. (ed.). Nova Biomedical Books, 60 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  23. Published

    A Unified Discussion on the Concept of Score Functions Used in the Context of Nonparametric Linkage Analysis

    Ängquist, Lars, 2008, In: Bioinformatics and Biology Insights. 2, p. 119-132 PMID:19812770.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Strategies for conditional two-locus nonparametric linkage analysis

    Ängquist, Lars, Hössjer, O. & Groop, L., 1 Jul 2008, In: Human Heredity. 66, 3, p. 138-156 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    The effects of soy isoflavones on obesity

    Ørgaard, A. & Jensen, L., 5 Jun 2008, In: Experimental Biology and Medicine (Maywood). 233, 9, p. 1066-80 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. 2007
  27. Published

    Concentrations of the acute phase reactants high-sensitive C-reactive protein and YKL-40 and of interleukin-6 before and after treatment in patients with acromegaly and growth hormone deficiency

    Andreassen, Mikkel, drb459, drb459 & Kristensen, L. Ø., Dec 2007, In: Clinical Endocrinology. 67, 6, p. 909-16 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review