Novo Nordisk Foundation Center for Basic Metabolic Research

  1. 2007
  2. Published

    Discovery and uses of pegvisomant: A growth hormone antagonist

    Berryman, D. E., Palmer, A. J., Gosney, E. S., Swaminathan, S., DeSantis, D. & Kopchick, J. J., 1 Dec 2007, In: Endokrynologia Polska. 58, 4, p. 322-329 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  3. Published

    Glucagon-like peptide-2 in umbilical cord blood from mature infants

    Bodé, S., Hartmann, Bolette, Holst, Jens Juul & Greisen, Gorm, 2007, In: Neonatology. 91, 1, p. 49-53 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    A common haplotype in the G-protein-coupled receptor gene GPR74 is associated with leanness and increased lipolysis

    Dahlman, I., Dicker, A., Jiao, H., Kere, J., Blomqvist, L., van Harmelen, V., Hoffstedt, J., Borch-Johnsen, K., Jorgensen, T., Hansen, Torben, Pedersen, Oluf Borbye, Laakso, M. & Arner, P., 2007, In: American Journal of Human Genetics. 80, 6, p. 1115-24 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Rosiglitazone monotherapy for type 2 diabetes mellitus-too soon to ADOPT?

    Gaede, P. & Pedersen, Oluf Borbye, 2007, In: Nature clinical practice. Endocrinology & metabolism. 3, 6, p. 456-7 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1α

    Gerhart-Hines, Zach, Rodgers, J. T., Bare, O., Lerin, C., Kim, S. H., Mostoslavsky, R., Alt, F. W., Wu, Z. & Puigserver, P., 4 Apr 2007, In: EMBO Journal. 26, 7, p. 1913-1923 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Studies of the associations between functional beta2-adrenergic receptor variants and obesity, hypertension and type 2 diabetes in 7,808 white subjects

    Gjesing, A. P., Andersen, G., Burgdorf, Kristoffer Sølvsten, Borch-Johnsen, K., Jørgensen, T., Hansen, Torben & Pedersen, Oluf Borbye, Mar 2007, In: Diabetologia. 50, 3, p. 563-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Porcine transcriptome analysis based on 97 non-normalized cDNA libraries and assembly of 1,021,891 expressed sequence tags

    Gorodkin, J., Cirera, S., Hedegaard, J., Gilchrist, M. J., Panitz, F., Jørgensen, C., Scheibye-Knudsen, K., Arvin, T., Lumholdt, S., Sawera, M., Green, T., Nielsen, B., Havgaard, J. H., Rosenkilde, C., Wang, J., Li, H., Li, R., Liu, B., Hu, S., Dong, W. & 16 others, Li, W., Yu, J., Wang, J., Staefeldt, H., Wernersson, R., Madsen, L. B., Thomsen, B. S., Hornshøj, H., Bujie, Z., Wang, X., Wang, X., Bolund, L., Brunak, Søren, Yang, H., Bendixen, C. & Fredholm, Merete, 2007, In: Genome Biology. 8, R45, p. R45 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Studies of the common DIO2 Thr92Ala polymorphism and metabolic phenotypes in 7342 Danish white subjects

    Grarup, N., Lepola, Mette Andersen, Andreasen, C. H., Albrechtsen, Anders, Borch-Johnsen, K., Jørgensen, T., Auwerx, J., Schmitz, O., Hansen, Torben & Pedersen, Oluf Borbye, 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 1, p. 363-6 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes

    Gudmundsson, J., Sulem, P., Steinthorsdottir, V., Bergthorsson, J. T., Thorleifsson, G., Manolescu, A., Rafnar, T., Gudbjartsson, D., Agnarsson, B. A., Baker, A., Sigurdsson, A., Benediktsdottir, K. R., Jakobsdottir, M., Blondal, T., Stacey, S. N., Helgason, A., Gunnarsdottir, S., Olafsdottir, A., Kristinsson, K. T., Birgisdottir, B. & 55 others, Ghosh, S., Thorlacius, S., Magnusdottir, D., Stefansdottir, G., Kristjansson, K., Bagger, Y., Wilensky, R. L., Reilly, M. P., Morris, A. D., Kimber, C. H., Adeyemo, A., Chen, Y., Zhou, J., So, W., Tong, P. C. Y., Ng, M. C. Y., Hansen, Torben, Andersen, G., Borch-Johnsen, K., Jorgensen, T., Tres, A., Fuertes, F., Ruiz-Echarri, M., Asin, L., Saez, B., van Boven, E., Klaver, S., Swinkels, D. W., Aben, K. K., Graif, T., Cashy, J., Suarez, B. K., van Vierssen Trip, O., Frigge, M. L., Ober, C., Hofker, M. H., Wijmenga, C., Christiansen, C., Rader, D. J., Palmer, C. N. A., Rotimi, C., Chan, J. C. N., Pedersen, Oluf Borbye, Sigurdsson, G., Benediktsson, R., Jonsson, E., Einarsson, G. V., Mayordomo, J. I., Catalona, W. J., Kiemeney, L. A., Barkardottir, R. B., Gulcher, J. R., Thorsteinsdottir, U., Kong, A. & Stefansson, K., 2007, In: Nature Genetics. 39, 8, p. 977-983 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    The BIGTT test: a novel test for simultaneous measurement of pancreatic beta-cell function, insulin sensitivity, and glucose tolerance

    Hansen, Torben, Drivsholm, Thomas, Urhammer, S. A., Palacios, R. T., Vølund, A., Borch-Johnsen, K. & Pedersen, Oluf Borbye, 2007, In: Diabetes Care. 30, 2, p. 257-262 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution

    Helgason, A., Pálsson, S., Thorleifsson, G., Grant, S. F. A., Emilsson, V., Gunnarsdottir, S., Adeyemo, A., Chen, Y., Chen, G., Reynisdottir, I., Benediktsson, R., Hinney, A., Hansen, T., Andersen, G., Borch-Johnsen, K., Jorgensen, T., Schäfer, H., Faruque, M., Doumatey, A., Zhou, J. & 13 others, Wilensky, R. L., Reilly, M. P., Rader, D. J., Bagger, Y., Christiansen, C., Sigurdsson, G., Hebebrand, J., Pedersen, Oluf Borbye, Thorsteinsdottir, U., Gulcher, J. R., Kong, A., Rotimi, C. & Stefánsson, K., 2007, In: Nature Genetics. 39, 2, p. 218-25 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Disassociation of bone resorption and formation by GLP-2: a 14-day study in healthy postmenopausal women

    Henriksen, D. B., Alexandersen, P., Hartmann, Bolette, Adrian, C. L., Byrjalsen, I., Bone, H. G., Holst, Jens Juul & Christiansen, C., Mar 2007, In: Bone. 40, 3, p. 723-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Hyperphosphorylation and low protein content of muscle glycogen synthase contribute to insulin resistance in polycystic ovary syndrome: effects of pioglitazone treatment

    Hojlund, K., Glintborg, D., Andersen, N. R., Birk, Jesper Bratz, Treebak, Jonas Thue, Beck-Nielsen, H. & Wojtaszewski, Jørgen F P, 2007, In: Diabetologia.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Bone resorption is decreased postprandially by intestinal factors and glucagon-like peptide-2 is a possible candidate

    Holst, Jens Juul, Hartmann, Bolette, Gottschalck, I. B., Jeppesen, Palle Bekker, Miholic, J. & Henriksen, D. B., Jul 2007, In: Scandinavian Journal of Gastroenterology. 42, 7, p. 814-20 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    The “mesh” as evidence – model comparison and alternative interpretations of feedback

    Hulme, Oliver James & Whiteley, Louise, 2007, In: Behavioral and Brain Sciences. 30

    Research output: Contribution to journalComment/debateCommunication

  17. Published

    The functional Pro129Thr variant of the FAAH gene is not associated with various fat accumulation phenotypes in a population-based cohort of 5,801 whites

    Jensen, D. P., Lepola, Mette Andersen, Hansen, L., Eiberg, Hans Rudolf Lytchoff, Borch-Johnsen, K., Jørgensen, T., Hansen, Torben, Pedersen, Oluf Borbye & Andreasen, C. H., 2007, In: Journal of Molecular Medicine. 85, 5, p. 445-9 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Polymorphisms in the 3' UTR in the neurocalcin delta gene affect mRNA stability, and confer susceptibility to diabetic nephropathy

    Kamiyama, M., Kobayashi, M., Araki, S., Iida, A., Tsunoda, T., Kawai, K., Imanishi, M., Nomura, M., Babazono, T., Iwamoto, Y., Kashiwagi, A., Kaku, K., Kawamori, R., Ng, D. P. K., Hansen, Torben, Gaede, P., Pedersen, Oluf Borbye, Nakamura, Y. & Maeda, S., 2007, In: Human Genetics. 122, 3-4, p. 397-407 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    The Treeterbi and Parallel Treeterbi algorithms: efficient, optimal decoding for ordinary, generalized and pair HMMs.

    Keibler, E., Arumugam, Mani & Brent, M. R., Mar 2007, In: Bioinformatics. 23, 5, p. 545-554 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Genetic analysis of the estrogen-related receptor alpha and studies of association with obesity and type 2 diabetes

    Larsen, L. H., Rose, C. S., Sparsø, T., Overgaard, J., Torekov, Signe Sørensen, Grarup, N., Jensen, Dan Funck, Albrechtsen, Anders, Andersen, G., Ek, J., Glümer, C., Borch-Johnsen, K., Jørgensen, Tina, Hansen, Teis Schjals & Pedersen, Oluf Borbye, 2007, In: International Journal of Obesity. 31, 2, p. 365-70 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Porcine glucagon-like peptide-2: structure, signaling, metabolism and effects

    Pedersen, N. B., Hjøllund, K. R., Johnsen, A. H., Ørskov, Cathrine, Rosenkilde, Mette, Hartmann, B. & Holst, Jens Juul, 2007, In: Regulatory Peptides. 146, 1-3, p. 310-320 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    The human PINK1 locus is regulated in vivo by a non-coding natural antisense RNA during modulation of mitochondrial function

    Schéele, Camilla Charlotte Nielsen, Petrovic, N., Faghihi, M. A., Lassmann, T., Fredriksson, K., Rooyackers, O., Wahlestedt, C., Good, L. & Timmons, J. A., 15 Mar 2007, In: BMC Genomics. 8, p. 74

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes

    Sparsø, T., Andersen, G., Nielsen, T., Burgdorf, K. S., Gjesing, A. M. P., Nielsen, A. L., Albrechtsen, Anders, Rasmussen, S. S., Jørgensen, T., Borch-Johnsen, K., Sandbaek, A., Lauritzen, T., Madsbad, Sten, Hansen, Torben & Pedersen, Oluf Borbye, 2007, In: Diabetologia. 51, 1, p. 70-5 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Relationships between the functional PPARalpha Leu162Val polymorphism and obesity, type 2 diabetes, dyslipidaemia, and related quantitative traits in studies of 5799 middle-aged white people

    Sparsø, T., Hussain, M. S., Andersen, G., Hainerova, I., Borch-Johnsen, K., Jørgensen, T., Hansen, Torben & Pedersen, Oluf Borbye, 2007, In: Molecular Genetics and Metabolism. 90, 2, p. 205-9 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Studies of association of the CASQ1 rs2275703 polymorphism in relation to type 2 diabetes and related quantitative metabolic traits among 7,088 Danish whites

    Sparsø, T., Hussain, M. S., Borch-Johnsen, K., Jørgensen, T., Madsbad, Sten, Hansen, Torben, Pedersen, Oluf Borbye & Andersen, G., 2007, In: Molecular Genetics and Metabolism. 92, 3, p. 278-282 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    A variant in CDKAL1 influences insulin response and risk of type 2 diabetes

    Steinthorsdottir, V., Thorleifsson, G., Reynisdottir, I., Benediktsson, R., Jonsdottir, T., Walters, G. B., Styrkarsdottir, U., Gretarsdottir, S., Emilsson, V., Ghosh, S., Baker, A., Snorradottir, S., Bjarnason, H., Ng, M. C. Y., Hansen, T., Bagger, Y., Wilensky, R. L., Reilly, M. P., Adeyemo, A., Chen, Y. & 25 others, Zhou, J., Gudnason, V., Chen, G., Huang, H., Lashley, K., Doumatey, A., So, W., Ma, R. C. Y., Andersen, G., Borch-Johnsen, K., Jorgensen, T., van Vliet-Ostaptchouk, J. V., Hofker, M. H., Wijmenga, C., Christiansen, C., Rader, D. J., Rotimi, C., Gurney, M., Chan, J. C. N., Pedersen, Oluf Borbye, Sigurdsson, G., Gulcher, J. R., Thorsteinsdottir, U., Kong, A. & Stefansson, K., 2007, In: Nature Genetics. 39, 6, p. 770-5 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review