Novo Nordisk Foundation Center for Basic Metabolic Research

  1. 2005
  2. Published

    Substituted thiazoleacetic acids as CRTH2 receptor ligands

    Ulven, Trond, Frimurer, Thomas Michael, Rist, Ø., Kostenis, E., Högberg, T., Receveur, J. & Grimstrup, M., 2005, Patent No. WO 2005/116001 A1

    Research output: Patent

  3. Published

    Closing in on the C. elegans ORFeome by cloning TWINSCAN predictions

    Wei, C., Lamesch, P., Arumugam, Mani, Rosenberg, J., Hu, P., Vidal, M. & Brent, M. R., 2005, In: Genome Research. 15, 4, p. 577-82 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Mutation analysis of the MCHR1 gene in human obesity

    Wermter, A-K., Reichwald, K., Büch, T., Geller, F., Platzer, C., Huse, K., Hess, C., Remschmidt, H., Gudermann, T., Preibisch, G., Siegfried, W., Goldschmidt, H-P., Li, W-D., Price, R. A., Biebermann, H., Krude, H., Vollmert, C., Wichmann, H-E., Illig, T., Sørensen, T. I. A. & 11 others, Astrup, A., Larsen, L. H., Pedersen, Oluf Borbye, Eberlé, D., Clément, K., Blundell, J., Wabitsch, M., Schäfer, H., Platzer, M., Hinney, A. & Hebebrand, J., 2005, In: European Journal of Endocrinology. 152, 6, p. 851-62 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Effect of three types of additives in poor solvent on preparation of sustained-release nitrendipine microspheres by the quasi-emulsion solvent diffusion method

    Yang, Mingshi, Cui, F., Fan, Yong, You, B., Ren, K., Feng, H. & Kawashima, Y., 1 Mar 2005, In: Journal of Drug Delivery Science and Technology. 15, 2, p. 129-135 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Improving the calculation of statistical significance in genome-wide scans

    Ängquist, Lars & Hössjer, O., 1 Oct 2005, In: Biostatistics. 6, 4, p. 520-538 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Parathyroid scintigraphy during hypocalcaemia in primary hyperparathyroidism

    Øgard, C. G., drb459, drb459, Thomsen, J. B., Jakobsen, H., Almdal, Thomas Peter, Nielsen, S. L. & drb459, drb459, May 2005, In: Clinical Physiology and Functional Imaging. 25, 3, p. 166-70 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 2004
  9. Published

    The independent effect of type 2 diabetes mellitus on ischemic heart disease, stroke, and death: a population-based study of 13,000 men and women with 20 years of follow-up

    Almdal, Thomas Peter, Scharling, H., Jensen, J. S. & drb459, drb459, 12 Jul 2004, In: J A M A Internal Medicine. 164, 13, p. 1422-6 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    EMPRR: A high-dimensional EM-based piecewise regression algorithm

    Arumugam, Mani & Scott, S. D., 2004, Proceedings of the 2004 International Conference on Machine Learning and Applications, ICMLA '04. Kantardzic, M., Nasraoui, O. & Milanova, M. (eds.). p. 264-271 8 p. (Proceedings of the 2004 International Conference on Machine Learning and Applications, ICMLA '04).

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

  11. Published

    Mutation analysis of NR0B2 among 1545 Danish men identifies a novel c.278G>A (p.G93D) variant with reduced functional activity

    Echwald, S. M., Andersen, K. L., Sørensen, Thorkild I.A., Larsen, L. H., Andersen, T., Tonooka, N., Tomura, H., Takeda, J. & Pedersen, Oluf Borbye, 2004, In: Human Mutation. 24, 5, p. 381-387 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Transcriptional profiling of extracellular amino acid sensing in Saccharomyces cerevisiae and the role of Stp 1 p and Stp2p

    Eckert-Boulet, N., Nielsen, P. S., Friis, Carsten, Moreira dos Santos, M., Nielsen, J., Kielland-Brandt, M. C. & Regenberg, Birgitte, 1 Jun 2004, In: Yeast. 21, 8, p. 635-648 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    The potential role of SOCS-3 in the interleukin-1beta-induced desensitization of insulin signaling in pancreatic beta-cells

    Emanuelli, Brice, Glondu, M., Filloux, C., Peraldi, P. & Van Obberghen, E., Dec 2004, In: Diabetes. 53 Suppl 3, p. S97-S103

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Keeping hens in tents - Experiences from the first year

    Forkman, Björn, Andersen, Daniel Bjørklund, Hindrup, B. & Horsted, K., Apr 2004, In: British Poultry Science. 45, SUPPL. 1, p. S37-S38

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published
  16. Published

    Cyclic Quinoline compounds for use in MCH receptor related disorders

    Frimurer, Thomas Michael, Ulven, Trond, Högberg, T., Nørregaard, P. K., Little, P. B. & Receveur, J., 2004, Patent No. WO 2004/052371

    Research output: Patent

  17. Published

    Quinoline compounds for use in MCH receptor related disorders

    Frimurer, Thomas Michael, Ulven, Trond, Högberg, T., Nørregaard, P. K., Little, P. B. & Receveur, J., 2004, Patent No. WO 2004/052370

    Research output: Patent

  18. Published

    Intensive integrated therapy of type 2 diabetes: implications for long-term prognosis

    Gaede, P. & Pedersen, Oluf Borbye, 2004, In: Diabetes. 53 Suppl 3, p. S39-47

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Remission to normoalbuminuria during multifactorial treatment preserves kidney function in patients with type 2 diabetes and microalbuminuria

    Gaede, P., Tarnow, L., Vedel, P., Parving, H. & Pedersen, Oluf Borbye, 2004, In: Nephrology, Dialysis, Transplantation. 19, 11, p. 2784-8 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Target intervention against multiple-risk markers to reduce cardiovascular disease in patients with type 2 diabetes

    Gaede, P. & Pedersen, Oluf Borbye, 2004, In: Annals of Medicine. 36, 5, p. 355-66 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Genome sequence of the Brown Norway rat yields insights into mammalian evolution

    Gibbs, R. A., Weinstock, G. M., Metzker, M. L., Muzny, D. M., Sodergren, E. J., Scherer, S., Scott, G., Steffen, D., Worley, K. C., Burch, P. E., Okwuonu, G., Hines, S., Lewis, L., DeRamo, C., Delgado, O., Dugan-Rocha, S., Miner, G., Morgan, M., Hawes, A., Gill, R. & 31 others, Celera, Holt, R. A., Adams, M. D., Amanatides, P. G., Baden-Tillson, H., Barnstead, M., Chin, S., Evans, C. A., Ferriera, S., Fosler, C., Glodek, A., Gu, Z., Jennings, D., Kraft, C. L., Nguyen, T., Pfannkoch, C. M., Sitter, C., Sutton, G. G., Venter, J. C., Woodage, T., Smith, D., Lee, H., Gustafson, E., Cahill, P., Kana, A., Doucette-Stamm, L., Weinstock, K., Fechtel, K., Weiss, R. B., Arumugam, Mani & Rat Genome Sequencing Project Consortium, R. G. S. P. C., 2004, In: Nature. 428, 6982, p. 493-521 29 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Variation in the interleukin-6 receptor gene associates with type 2 diabetes in Danish whites

    Hamid, Y. H., Urhammer, S. A., Jensen, D. P., Glümer, C., Borch-Johnsen, K., Jørgensen, T., Hansen, Torben & Pedersen, Oluf Borbye, 2004, In: Diabetes. 53, 12, p. 3342-5 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Expression profiling of insulin action in human myotubes: induction of inflammatory and pro-angiogenic pathways in relationship with glycogen synthesis and type 2 diabetes

    Hansen, L., Gaster, M., Oakeley, E. J., Brusgaard, K., Damsgaard Nielsen, E., Beck-Nielsen, H., Pedersen, Oluf Borbye & Hemmings, B. A., 2004, In: Biochemical and Biophysical Research Communications. 323, 2, p. 685-95 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Glucagon-like peptide-1 secretion is influenced by perfusate glucose concentration and by a feedback mechanism involving somatostatin in isolated perfused porcine ileum

    Hansen, L., Hartmann, Bolette, Mineo, H. & Holst, Jens Juul, 15 Apr 2004, In: Regulatory Peptides. 118, 1-2, p. 11-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    A novel syndrome of autosomal-dominant hyperinsulinemic hypoglycemia linked to a mutation in the human insulin receptor gene

    Højlund, K., Hansen, Torben, Lajer, M., Henriksen, J. E., Levin, K., Lindholm, J., Pedersen, Oluf Borbye & Beck-Nielsen, H., 2004, In: Diabetes. 53, 6, p. 1592-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Studies of the Ala/Val98 polymorphism of the hepatocyte nuclear factor-1alpha gene and the relationship to beta-cell function during an OGTT in glucose-tolerant women with and without previous gestational diabetes mellitus

    Lauenborg, J., Damm, Peter, Ek, J., Glümer, C., Jørgensen, Tina, Borch-Johnsen, K., Vestergaard, H., Hornnes, P., Pedersen, Oluf Borbye & Hansen, Torben, Dec 2004, In: Diabetic Medicine. 21, 12, p. 1310-5 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Increasing incidence of diabetes after gestational diabetes: a long-term follow-up in a Danish population

    Lauenborg, J., Hansen, Torben, Jensen, D. M., drb459, drb459, Mølsted-Pedersen, L., Hornnes, P., Locht, H., Pedersen, Oluf Borbye & Damm, Peter, 2004, In: Diabetes Care. 27, 5, p. 1194-9 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review