Novo Nordisk Foundation Center for Basic Metabolic Research

Prospective studies exploring the possible impact of an ID3 polymorphism on changes in obesity measures

Svendstrup, M., Appel, E. V. R., Sandholt, C. H., Ahluwalia, Tarun Veer Singh, Ängquist, Lars, Thuesen, B. H., Jørgensen, M. E., Pedersen, Oluf Borbye, Grarup, N., Hansen, Torben, Sørensen, Thorkild I.A. & drb459, drb459, 2018, In: Obesity. 26, 4, p. 747-754 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

FGF21, a liver hormone that inhibits alcohol intake in mice, increases in human circulation after acute alcohol ingestion and sustained binge drinking at Oktoberfest

Søberg, S., Andersen, E. S., Dalsgaard, N. B., Jarlhelt, I., Hansen, N. L., Hoffmann, N., Vilsbøll, Tina, Chenchar, A., Jensen, M., Grevengoed, Trisha Jean, Trammell, Sam, Knop, Filip Krag & Gillum, M. P., 2018, In: Molecular Metabolism. 11, p. 96-103 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Dairy Consumption and Body Mass Index Among Adults: Mendelian Randomization Analysis of 184802 Individuals from 25 Studies

Sørensen, Thorkild I.A., Linneberg, Allan René & Mendelian Randomization of Dairy Consumption Working Group, M. R. O. D. C. W. G., 2018, In: Clinical Chemistry. 64, 1, p. 183-191 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Godkendelse af personlig medicin

Sørensen, Thorkild I.A., 2018, In: Ugeskrift for Laeger. 180, p. 1054 1 p., V69798 .

Research output: Contribution to journal › Journal article › Research › peer-review

Interethnic analyses of blood pressure loci in populations of East Asian and European descent

The International Genomics of Blood Pressure (iGEN-BP) Consortium, T. I. G. O. B. P. (. C., 2018, In: Nature Communications. 9, 5052.

Research output: Contribution to journal › Journal article › Research › peer-review

Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation

Teumer, A., Chaker, L., Groeneweg, S., Li, Y., Di Munno, C., Barbieri, C., Ahluwalia, Tarun Veer Singh, Astrup, A., Linneberg, Allan René, Pedersen, Oluf Borbye, Sørensen, Thorkild I.A. & ThyroidOmics Consortium, T. C., 2018, In: Nature Communications. 9, 14 p., 4455.

Research output: Contribution to journal › Journal article › Research › peer-review

The effect of obesity on early fetal growth and pregnancy duration: a cohort study

Thagaard, I. N., Krebs, Lone, Holm, Jens-Christian, Christiansen, M., Møller, H., Lange, Theis & Larsen, T., 4 Aug 2018, In: Journal of Maternal - Fetal & Neonatal Medicine. 31, 22, p. 2941-2946 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Glucagon-like peptide-1 receptor agonists and cardiovascular disease: from LEADER to EXSCEL

Torekov, Signe Sørensen, 2018, In: Cardiovascular Research. 114, 10, p. e70-e71 2 p.

Research output: Contribution to journal › Comment/debate › Research › peer-review

Bidirectional GPR119 agonism requires peptide YY and glucose for activity in mouse and human colon mucosa

Tough, I. R., Forbes, S., Herzog, H., Jones, R. M., Schwartz, Thue W. & Cox, H. M., 1 Apr 2018, In: Endocrinology. 159, 4, p. 1704-1717

Research output: Contribution to journal › Journal article › Research › peer-review

The HETE Is on FFAR1 and Pancreatic Islet Cells

Trauelsen, Mette, Lückmann, Michael, Frimurer, Thomas Michael & Schwartz, Thue W., 2018, In: Cell Metabolism. 27, 2, p. 273-275 3 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

Turcot, V., Lu, Y., Highland, H. M., Bang, L. E., Benn, M., Kamstrup, P. R., Bork-Jensen, J., Frikke-Schmidt, R., Gjesing, A. P., Grarup, N., Hansen, T., Have, C. T., Jørgensen, T., Nielsen, S. F., Linneberg, A. R., Pedersen, O., Pers, T. H., Vestergaard, H., Nordestgaard, B., Tybjærg-Hansen, A. & 15 others, Varbo, A., CHD Exome+ Consortium, C. E. C., EPIC-CVD Consortium, E. C., ExomeBP Consortium, E. C., Global Lipids Genetics Consortium, G. L. G. C., GoT2D Genes Consortium, G. G. C., EPIC-InterAct Consortium, E. C., INTERVAL Study, I. S., ReproGen Consortium, R. C., T2D-Genes Consortium, T. C., The MAGIC Investigators, T. M. I., Understanding Society Scientific Group, U. S. S. G., Lindgren, C. M., Hirschhorn, J. N. & Loos, R. J. F., 1 Jan 2018, In: Nature Genetics. 50, p. 26-41 16 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Metabolic and hepatic effects of liraglutide, obeticholic acid and elafibranor in diet-induced obese mouse models of biopsy-confirmed nonalcoholic steatohepatitis

Tølbøl, K. S., Kristiansen, M. N. B., Hansen, H. H., Veidal, S. S., Rigbolt, K. T. G., Gillum, M. P., Jelsing, J., Vrang, N. & Feigh, M., 2018, In: World Journal of Gastroenterology. 24, 2, p. 179-194 16 p.

Research output: Contribution to journal › Journal article › Research › peer-review

BMI at school age and incident asthma admissions in early adulthood: A prospective study of 310,211 children

Ulrik, Charlotte Suppli, Lophaven, S. N., Andersen, Zorana Jovanovic, Sørensen, Thorkild I.A. & Baker, J. L., 25 May 2018, In: Clinical Epidemiology. 10, p. 605-612 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Duodenal L cell density correlates with features of metabolic syndrome and plasma metabolites

Van Baar, A. C. G., Prodan, A., Wahlgren, C. D., Poulsen, Steen Seier, Knop, Filip Krag, Groen, A. K., Bergman, J. J., Nieuwdorp, M. & Levin, E., 2018, In: Endocrine Connections. 7, 5, p. 673-680

Research output: Contribution to journal › Journal article › Research › peer-review

Reduced obesity, diabetes, and steatosis upon cinnamon and grape pomace are associated with changes in gut microbiota and markers of gut barrier

Van Hul, M., Geurts, L., Plovier, H., Druart, C., Everard, A., Ståhlman, M., Rhimi, M., Chira, K., Teissedre, P., Delzenne, N. M., Maguin, E., Guilbot, A., Brochot, A., Gérard, P., Bäckhed, F. & Cani, P. D., 2018, In: American Journal of Physiology: Endocrinology and Metabolism. 314, 4, p. E334-E352 19 p.

Research output: Contribution to journal › Journal article › Research › peer-review

A genome-wide association study of diabetic kidney disease in subjects with type 2 diabetes

Van Zuydam, N. R., Ahlqvist, E., Sandholm, N., Deshmukh, H., William Rayner, N., Abdalla, M., Ladenvall, C., Ziemek, D., Fauman, E., Robertson, N. R., McKeigue, P. M., Valo, E., Forsblom, C., Harjutsalo, V., Perna, A., Rurali, E., Loredana Marcovecchio, M., Igo, R. P., Lajer, M., Ahluwalia, T. S. & 7 others, Linneberg, Allan René, Witte, D. R., Grarup, N., Pedersen, Oluf Borbye, Hansen, Torben, Rossing, Peter & SUrrogate markers for Micro- and Macrovascular hard endpoints for Innovative diabetes Tools (SUMMIT) Consortium, S. M. F. M. A. M. H. E. F. I. D. T. (. C., 2018, In: Diabetes. 67, 7, p. 1414-1427 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Ghrelin secretion in humans - a role for the vagus nerve?

Veedfald, Simon, Plamboeck, A., Hartmann, Bolette, Vilsbøll, Tina, Knop, Filip Krag, Deacon, Carolyn F., Svendsen, Lars Bo & Holst, Jens Juul, Jun 2018, In: Neurogastroenterology and Motility. 30, 6, e13295.

Research output: Contribution to journal › Journal article › Research › peer-review

Hyperosmolar Duodenal Saline Infusion Lowers Circulating Ghrelin and Stimulates Intestinal Hormone Release in Young Men

Veedfald, Simon, Wu, T., Bound, M., Grivell, J., Hartmann, Bolette, Rehfeld, Jens Frederik, Deacon, Carolyn F., Horowitz, M., Holst, Jens Juul & Rayner, C. K., 2018, In: Journal of Clinical Endocrinology & Metabolism. 103, 12, p. 4409-4418

Research output: Contribution to journal › Journal article › Research › peer-review

Elevated arterial lactate delays recovery of intracellular muscle pH after exercise

Volianitis, S., Secher, Niels H. & Quistorff, B., Nov 2018, In: European Journal of Applied Physiology. 118, 11, p. 2429-2434

Research output: Contribution to journal › Journal article › Research › peer-review

Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis

Waage, J., Standl, M., Curtin, J. A., Jessen, L. E., Thorsen, J., Tian, C., Schoettler, N., 23andMe Research Team, AAGC collaborators, Flores, C., Abdellaoui, A., Ahluwalia, T. S., Alves, A. C., Amaral, A. F. S., Antó, J. M., Arnold, A., Barreto-Luis, A., Baurecht, H., van Beijsterveldt, C. E. M., Bleecker, E. R. & 33 others, Bonàs-Guarch, S., Boomsma, D. I., Brix, S., Bunyavanich, S., Burchard, E. G., Chen, Z., Curjuric, I., Custovic, A., den Dekker, H. T., Dharmage, S. C., Dmitrieva, J., Duijts, L., Ege, M. J., Gauderman, W. J., Georges, M., Gieger, C., Gilliland, F., Granell, R., Gui, H., Hansen, Torben, Heinrich, J., Henderson, J., Hernandez-Pacheco, N., Holt, P., Imboden, M., Jaddoe, V. W. V., Jarvelin, M., Jarvis, D. L., Jensen, K. K., Nohr, E. A., Bisgaard, H., Strachan, D. P. & Bønnelykke, Klaus, 2018, In: Nature Genetics. 50, 8, p. 1072-1080

Research output: Contribution to journal › Letter › Research › peer-review

Maternal and fetal genetic contribution to gestational weight gain

Warrington, N. M., Richmond, R., Fenstra, B., Myhre, R., Gaillard, R., Paternoster, L., Wang, C. A., Beaumont, R. N., Das, S., Murcia, M., Barton, S. J., Espinosa, A., Thiering, E., Atalay, M., Pitkänen, N., Ntalla, I., Jonsson, A. E., Freathy, R., Karhunen, V., Tiesler, C. M. T. & 44 others, Allard, C., Crawford, A., Ring, S. M., Melbye, M., Magnus, P., Rivadeneira, F., Skotte, L., Hansen, Torben, Marsh, J., Guxens, M., Holloway, J. W., Grallert, H., Jaddoe, V. W. V., Lowe, W. L., Roumeliotaki, T., Hattersley, A. T., Lindi, V., Pahkala, K., Panoutsopoulou, K., Standl, M., Flexeder, C., Bouchard, L., Aagaard Nohr, E., Marina, L. S., Kogevinas, M., Niinikoski, H., Dedoussis, G., Heinrich, J., Reynolds, R. M., Lakka, T., Zeggini, E., Raitakari, O. T., Chatzi, L., Inskip, H. M., Bustamante, M., Hivert, M., Jarvelin, M., Sørensen, Thorkild I.A., Pennell, C., Felix, J. F., Jacobsson, B., Geller, F., Evans, D. M. & Lawlor, D. A., 2018, In: International journal of obesity (2005). 42, p. 775–784

Research output: Contribution to journal › Journal article › Research › peer-review

Evidence of a liver-alpha cell axis in humans: hepatic insulin resistance attenuates relationship between fasting plasma glucagon and glucagonotropic amino acids

Albrechtsen, Nicolai Jacob Wewer, Færch, K., Jensen, T. M., Witte, D. R., Pedersen, Jens, Mahendran, Y., Jonsson, Anna Elisabet, Galsgaard, Katrine Douglas, Winther-Sørensen, Marie, Torekov, Signe Sørensen, Lauritzen, T., Pedersen, Oluf Borbye, Knop, Filip Krag, Hansen, Torben, Jørgensen, M. E., Vistisen, D. & Holst, Jens Juul, 2018, In: Diabetologia. 61, 3, p. 671-680

Research output: Contribution to journal › Journal article › Research › peer-review

Hyperglucagonemia correlates with plasma levels of non-branched-chain amino acids in patients with liver disease independent of type 2 diabetes

Albrechtsen, Nicolai Jacob Wewer, Junker, A. E., Christensen, M., Hædersdal, S., Wibrand, F., Lund, A. M., Galsgaard, Katrine Douglas, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2018, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 314, 1, p. G91-G96

Research output: Contribution to journal › Journal article › Research › peer-review

Plasma Proteome Profiling Reveals Dynamics of Inflammatory and Lipid Homeostasis Markers after Roux-En-Y Gastric Bypass Surgery

Albrechtsen, Nicolai Jacob Wewer, Geyer, P. E., Doll, S., Treit, P. V., Bojsen-Møller, K. N., Martinussen, C., Jørgensen, N. B., Torekov, Signe Sørensen, Meier, F., Niu, Lili, Santos, A., Keilhauer, E. C., Holst, Jens Juul, Madsbad, Sten & Mann, Matthias, 2018, In: Cell Systems. 7, 6, p. 601-612

Research output: Contribution to journal › Journal article › Research › peer-review

Restricting glycolysis impairs brown adipocyte glucose and oxygen consumption

Winther, Sally, Isidor, Marie Sophie, Basse, A. L., Skjoldborg, N., Cheung, A., Quistorff, B. & Hansen, Jacob B., 2018, In: American Journal of Physiology: Endocrinology and Metabolism. 314, 3, p. E214-E223 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Universal infant health interventions and young adult outcomes

Wüst, Miriam, Mortensen, Erik Lykke, Osler, Merete & Sørensen, Thorkild I.A., 2018, In: Health Economics. 27, 8, p. 1319-1324 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function

Wyss, A. B., Sofer, T., Lee, M. K., Terzikhan, N., Nguyen, J. N., Lahousse, L., Latourelle, J. C., Smith, A. V., Bartz, T. M., Feitosa, M. F., Gao, W., Ahluwalia, T. S., Tang, W., Oldmeadow, C., Duan, Q., de Jong, K., Wojczynski, M. K., Wang, X-Q., Noordam, R., Hartwig, F. P. & 82 others, Jackson, V. E., Wang, T., Obeidat, M., Hobbs, B. D., Huan, T., Gui, H., Parker, M. M., Hu, D., Mogil, L. S., Kichaev, G., Jin, J., Graff, M., Harris, T. B., Kalhan, R., Heckbert, S. R., Paternoster, L., Burkart, K. M., Liu, Y., Holliday, E. G., Wilson, J. G., Vonk, J. M., Sanders, J. L., Barr, R. G., de Mutsert, R., Baptista Menezes, A. M., Adams, H. H. H., van den Berge, M., Joehanes, R., Levin, A. M., Liberto, J., Launer, L. J., Morrison, A. C., Sitlani, C. M., Celedon, J. C., Kritchevsky, S. B., Scott, R. J., Christensen, K., Rotter, J. I., Bonten, T. N., Wehrmeister, F. C., Bosse, Y., Xiao, S., Oh, S., Franceschini, N., Brody, J. A., Kaplan, R. C., Lohman, K., McEvoy, M., Province, M. A., Rosendaal, F. R., Taylor, K. D., Nickle, D. C., Williams, L. K., Burchard, E. G., Wheeler, H. E., Sin, D. D., Gudnason, V., North, K. E., Fornage, M., Psaty, B. M., Myers, R. H., O'Connor, G., Hansen, Torben, Laurie, C. C., Cassano, P. A., Sung, J., Kim, W. J., Attia, J. R., Lange, L., Boezen, H. M., Thyagarajan, B., Rich, S. S., Mook-Kanamori, D. O., Horta, B. L., Uitterlinden, A. G., Im, H. K., Cho, M. H., Brusselle, G. G., Gharib, S. A., Dupuis, J., Manichaikul, A. & London, S. J., 2018, In: Nature Communications. 9, 15 p., 2976.

Research output: Contribution to journal › Journal article › Research › peer-review

Molecular genetic overlap between migraine and major depressive disorder

Yang, Y., Zhao, H., Boomsma, D. I., Ligthart, L., Belin, A. C., Smith, G. D., Esko, T., Freilinger, T. M., Hansen, T. F., Ikram, M. A., Kallela, M., Kubisch, C., Paraskevi, C., Strachan, D. P., Wessman, M., Gormley, P., Anttila, V., Winsvold, B. S., Palta, P., Esko, T. & 30 others, Pers, Tune H, Farh, K. H., Cuenca-Leon, E., Muona, M., Furlotte, N. A., Kurth, T., Ingason, A., McMahon, G., Ligthart, L., Terwindt, G. M., Kallela, M., Freilinger, T. M., Ran, C., Gordon, S. G., Stam, A. H., Steinberg, S., Borck, G., Koiranen, M., Quaye, L., Adams, H. H. H., Lehtimäki, T., Sarin, A. P., Wedenoja, J., Hinds, D. A., Buring, J. E., Schürks, M., Christensen, A. F., Hansen, Thomas Folkmann, Werge, Thomas & Olesen, Jes, 2018, In: European Journal of Human Genetics. 26, 8, p. 1202-1216 15 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Cytoglobin affects tumorigenesis and the expression of ulcerative colitis-associated genes under chemically induced colitis in mice

Yassin, M., Kissow, Hannelouise, Vainer, B., Joseph, P. D., Hay-Schmidt, Anders, Olsen, J. & Pedersen, Anders Elm, 2018, In: Scientific Reports. 8, p. 1-16 6905.

Research output: Contribution to journal › Journal article › Research › peer-review

Rectal insulin instillation inhibits inflammation and tumor development in chemically-induced colitis

Yassin, M., Sadowska, Z., Tritsaris, Katerina, Kissow, Hannelouise, Hansen, Camilla Hartmann Friis, Forman, Julie Lyng, Rogler, G., Troelsen, J. T., Pedersen, Anders Elm & Olsen, Jørgen, 2018, In: Journal of Crohn's and Colitis. 12, 12, p. 1459–1474 16 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genetic and environmental factors affecting birth size variation: a pooled individual-based analysis of secular trends and global geographical differences using 26 twin cohorts

Yokoyama, Y., Jelenkovic, A., Hur, Y-M., Sund, R., Fagnani, C., Stazi, M. A., Brescianini, S., Ji, F., Ning, F., Pang, Z., Knafo-Noam, A., Mankuta, D., Abramson, L., Rebato, E., Hopper, J. L., Cutler, T. L., Saudino, K. J., Nelson, T. L., Whitfield, K. E., Corley, R. P. & 40 others, Huibregtse, B. M., Derom, C. A., Vlietinck, R. F., Loos, Ruth, Llewellyn, C. H., Fisher, A., Bjerregaard-Andersen, M., Beck-Nielsen, H., Sodemann, M., Krueger, R. F., McGue, M., Pahlen, S., Bartels, M., van Beijsterveldt, C. E. M., Willemsen, G., Harris, J. R., Brandt, I., Nilsen, T. S., Craig, J. M., Saffery, R., Dubois, L., Boivin, M., Brendgen, M., Dionne, G., Vitaro, F., Haworth, C. M. A., Plomin, R., Bayasgalan, G., Narandalai, D., Rasmussen, F., Tynelius, P., Tarnoki, A. D., Tarnoki, D. L., Ooki, S., Rose, R. J., Pietilainen, K. H., Sørensen, Thorkild I.A., Boomsma, D. I., Kaprio, J. & Silventoinen, K., 2018, In: International Journal of Epidemiology. 47, 4, p. 1195-1206 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Contributions of mean and shape of blood pressure distribution to worldwide trends and variations in raised blood pressure: a pooled analysis of 1018 population-based measurement studies with 88.6 million participants

Zhou, B., Bentham, J., Di Cesare, M., Bixby, H., Danaei, G., Hajifathalian, K., Taddei, C., Carrillo-Larco, R. M., Djalalinia, S., Khatibzadeh, S., Lugero, C., Peykari, N., Zhang, W. Z., Bennett, J., Bilano, V., Stevens, G. A., Cowan, M. J., Riley, L. M., Chen, Z., Hambleton, I. R. & 840 others, Jackson, R. T., Kengne, A. P., Khang, Y., Laxmaiah, A., Liu, J., Malekzadeh, R., Neuhauser, H. K., Soric, M., Starc, G., Sundstrom, J., Woodward, M., Ezzati, M., Abarca-Gomez, L., Abdeen, Z. A., Abu-Rmeileh, N. M., Acosta-Cazares, B., Adams, R. J., Aekplakorn, W., Afsana, K., Aguilar-Salinas, C. A., Agyemang, C., Ahmad, N. A., Ahmadvand, A., Ahrens, W., Ajlouni, K., Akhtaeva, N., Al-Raddadi, R., Ali, M. M., Ali, O., Alkerwi, A., Aly, E., Amarapurkar, D. N., Amouyel, P., Amuzu, A., Andersen, L. B., Anderssen, S. A., Ängquist, Lars, Anjana, R. M., Ansong, D., Aounallah-Skhiri, H., Araujo, J., Ariansen, I., Aris, T., Arlappa, N., Arveiler, D., Aryal, K. K., Aspelund, T., Assah, F. K., Assuncao, M. C. F., Avdicova, M., Azevedo, A., Azizi, F., Babu, B. V., Bahijri, S., Balakrishna, N., Bamoshmoosh, M., Banach, M., Bandosz, P., Banegas, J. R., Barbagallo, C. M., Barcelo, A., Barkat, A., Barros, A. J. D., Barros, M. V., Bata, I., Batieha, A. M., Batyrbek, A., Baur, L. A., Beaglehole, R., Ben Romdhane, H., Benet, M., Benson, L. S., Bernabe-Ortiz, A., Bernotiene, G., Bettiol, H., Bhagyalaxmi, A., Bharadwaj, S., Bhargava, S. K., Bi, Y., Bikbov, M., Bista, B., Bjerregaard, P., Bjertness, E., Bjertness, M. B., Bjorkelund, C., Blokstra, A., Bo, S., Bobak, M., Boeing, H., Boggia, J. G., Boissonnet, C. P., Bongard, V., Borchini, R., Bovet, P., Braeckman, L., Brajkovich, I., Branca, F., Breckenkamp, J., Brenner, H., Brewster, L. M., Bruno, G., Bueno-de-Mesquita, Bugge, A., Burns, C., Bursztyn, M., Cabrera de Leon, A., Cacciottolo, J., Cai, H., Cameron, C., Can, G., Candido, A. P. C., Capuano, V., Cardoso, V. C., Carlsson, A. C., Carvalho, M. J., Casanueva, F. F., Casas, J., Caserta, C. A., Chamukuttan, S., Chan, A. W., Chan, Q., Chaturvedi, H. K., Chaturvedi, N., Chen, C., Chen, F., Chen, H., Chen, S., Chen, Z., Cheng, C., Cherkaoui Dekkaki, I., Chetrit, A., Chiolero, A., Chiou, S., Chirita-Emandi, A., Chirlaque, M., Cho, B., Cho, Y., Christofaro, D. G., Chudek, J., Cifkova, R., Cinteza, E., Claessens, F., Clays, E., Concin, H., Cooper, C., Cooper, R., Coppinger, T. C., Costanzo, S., Cottel, D., Cowell, C., Craig, C. L., Crujeiras, A. B., Cruz, J. J., D'Arrigo, G., d'Orsi, E., Dallongeville, J., Damasceno, A., Danaei, G., Dankner, R., Dantoft, T. M., Dauchet, L., Davletov, K., De Backer, G., De Bacquer, D., de Gaetano, G., De Henauw, S., de Oliveira, P. D., De Smedt, D., Deepa, M., Dehghan, A., Delisle, H., Deschamps, V., Dhana, K., Di Castelnuovo, A. F., Dias-da-Costa, J. S., Diaz, A., Dickerson, T. T., Djalalinia, S., Do, H. T. P., Dobson, A. J., Donfrancesco, C., Donoso, S. P., Doering, A., Dorobantu, M., Doua, K., Drygas, W., Dulskiene, V., Dzakula, A., Dzerve, V., Dziankowska-Zaborszczyk, E., Eggertsen, R., Ekelund, U., El Ati, J., Elliott, P., Elosua, R., Erasmus, R. T., Erem, C., Eriksen, L., Eriksson, J. G., Escobedo-de la Pena, J., Evans, A., Faeh, D., Fall, C. H., Farzadfar, F., Felix-Redondo, F. J., Ferguson, T. S., Fernandes, R. A., Fernandez-Berges, D., Ferrante, D., Ferrari, M., Ferreccio, C., Ferrieres, J., Finn, J. D., Fischer, K., Foger, B., Foo, L. H., Forslund, A., Forsner, M., Fouad, H. M., Francis, D. K., Franco, M. D. C., Franco, O. H., Frontera, G., Fuchs, F. D., Fuchs, S. C., Fujita, Y., Furusawa, T., Gaciong, Z., Galvano, F., Garcia-de-la-Hera, M., Gareta, D., Garnett, S. P., Gaspoz, J., Gasull, M., Gates, L., Geleijnse, J. M., Ghasemian, A., Ghimire, A., Giampaoli, S., Gianfagna, F., Gill, T. K., Giovannelli, J., Goldsmith, R. A., Goncalves, H., Gonzalez-Gross, M., Gonzalez-Rivas, J. 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M., Vanderschueren, D., Vanuzzo, D., Vatten, L., Vega, T., Velasquez-Melendez, G., Veronesi, G., Verschuren, W. M. M., Verstraeten, R., Victora, C. G., Viet, L., Viikari-Juntura, E., Vineis, P., Vioque, J., Virtanen, J. K., Visvikis-Siest, S., Viswanathan, B., Vlasoff, T., Vollenweider, P., Voutilainen, S., Wade, A. N., Wagner, A., Walton, J., Bebakar, W. M. W., Mohamud, W. N. W., Wanderley, R. S. ,. J., Wang, M., Wang, Q., Wang, Y. X., Wang, Y., Wannamethee, S. G., Wareham, N., Wedderkopp, N., Weerasekera, D., Whincup, P. H., Widhalm, K., Widyahening, I. S., Wiecek, A., Wijga, A. H., Wilks, R. J., Willeit, J., Willeit, P., Williams, E. A., Wilsgaard, T., Wojtyniak, B., Wong-McClure, R. A., Wong, J. Y. Y., Wong, T. Y., Woo, J., Woodward, M., Wu, A. G., Wu, F. C., Wu, S., Xu, H., Yan, W., Yang, X., Ye, X., Yiallouros, P. K., Yoshihara, A., Younger-Coleman, N. O., Yusoff, A. F., Zainuddin, A. A., Zambon, S., Zampelas, A., Zdrojewski, T., Zeng, Y., Zhao, D., Zhao, W., Zheng, W., Zheng, Y., Zhu, D., Zhussupov, B., Zimmermann, E. & Cisneros, J. Z., Jun 2018, In: International Journal of Epidemiology. 47, 3, p. 872-883 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

G9a regulates temporal preimplantation developmental program and lineage segregation in blastocyst

Zylicz, Jan Jakub, Borensztein, M., Wong, F. C. K., Huang, Yun, Lee, C., Dietmann, S. & Surani, M. A., 10 May 2018, In: eLife. 7, e33361.

Research output: Contribution to journal › Journal article › Research › peer-review

A Diurnal Rhythm in Brown Adipose Tissue Causes Rapid Clearance and Combustion of Plasma Lipids at Wakening

van den Berg, R., Kooijman, S., Noordam, R., Ramkisoensing, A., Abreu-Vieira, G., Tambyrajah, L. L., Dijk, W., Ruppert, P., Mol, I. M., Kramar, B., Caputo, R., Puig, L. S., de Ruiter, E. M., Kroon, J., Hoekstra, M., van der Sluis, R. J., Meijer, O. C., Willems van Dijk, K., van Kerkhof, L. W. M., Christodoulides, C. & 8 others, Karpe, F., Gerhart-Hines, Zach, Kersten, S., Meijer, J. H., Coomans, C. P., van Heemst, D., Biermasz, N. R. & Rensen, P. C. N., 2018, In: Cell Reports. 22, 13, p. 3521-3533 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The prebiotic inulin improves substrate metabolism and promotes short-chain fatty acid production in overweight to obese men

van der Beek, C. M., Canfora, E. E., Kip, A. M., Gorissen, S. H. M., Damink, S. W. M. O., van Eijk, H. M., Holst, Jens Juul, Blaak, E. E., Dejong, C. H. C. & Lenaerts, K., Oct 2018, In: Metabolism. 87, p. 25-35

Research output: Contribution to journal › Journal article › Research › peer-review

Childhood BMI growth trajectories and endometrial cancer risk

Aarestrup, J., Gamborg, M., Tilling, K., Ulrich, L. G., Sørensen, Thorkild I.A. & Baker, J. L., 15 Jan 2017, In: International Journal of Cancer. 140, 2, p. 310–315 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Carriers of a VEGFA enhancer polymorphism selectively binding CHOP/DDIT3 are predisposed to increased circulating levels of thyroid-stimulating hormone

Ahluwalia, Tarun Veer Singh, Troelsen, J. T., Balslev-Harder, M., Bork-Jensen, J., Thuesen, B. H., Cerqueira, C., Linneberg, Allan René, Grarup, N., Pedersen, Oluf Borbye, Hansen, Torben & Dalgaard, L. T., Mar 2017, In: Journal of Medical Genetics. 54, 3, p. 166-175 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production

Albrechtsen, N. J. W., Kuhre, R. E., Hornburg, D., Jensen, C. Z., Hornum, M., Dirksen, C., Svane, M., Gasbjerg, L. S., Jorgensen, N. B., Gabe, M. N., Balk-Moller, E., Albrechtsen, R., Winther-Sorensen, M., Galsgaard, K. D., Meissner, F., Jorsal, T., Lund, A., Vilsboll, T., Eliasen, R., Bojsen-Moller, K. N. & 9 others, Idorn, T., Deacon, Carolyn F., Knop, Filip Krag, Rosenkilde, Mette, Hartmann, Bolette, Feldt-Rasmussen, Bo, Mann, Matthias, Madsbad, Sten & Holst, Jens Juul, Nov 2017, In: Cell Reports. 21, 6, p. 1452-1460

Research output: Contribution to journal › Journal article › Research › peer-review

Genetic determinants of serum vitamin B12 and their relation to body mass index

Allin, K. H., Friedrich, N., Pietzner, M., Grarup, N., Thuesen, B. H., Linneberg, Allan René, Pisinger, C., Hansen, Torben, Pedersen, Oluf Borbye & Sandholt, C. H., Feb 2017, In: European Journal of Epidemiology. 32, 2, p. 125–134

Research output: Contribution to journal › Journal article › Research › peer-review

Grandpaternal-induced transgenerational dietary reprogramming of the unfolded protein response in skeletal muscle

Alm, P. S., de Castro Barbosa, T., Barrès, Romain, Krook, A. & Zierath, Juleen R, Jul 2017, In: Molecular Metabolism. 6, 7, p. 621-630 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genetic determinants of circulating GIP and GLP-1 concentrations

Almgren, P., Lindqvist, A., Krus, U., Hakaste, L., Ottosson-Laakso, E., Asplund, O., Sonestedt, E., Prasad, R. B., Laurila, E., Orho-Melander, M., Melander, O., Tuomi, T., Holst, Jens Juul, Nilsson, P. M., Wierup, N., Groop, L. & Ahlqvist, E., 2 Nov 2017, In: JCI insight. 2, 21, 13 p., e93306.

Research output: Contribution to journal › Journal article › Research › peer-review

A study of associations between early DHA status and fatty acid desaturase (FADS) SNP and developmental outcomes in children of obese mothers

Andersen, K. R., Harsløf, L. B. S., Schnurr, T. M., Hansen, Torben, Hellgren, L. I., Michaelsen, Kim F. & Lauritzen, Lotte, 2017, In: The British Journal of Nutrition. 117, 2, p. 278-286 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Diabetes-associated microbiota in fa/fa rats is modified by Roux-en-Y gastric bypass

Arora, Tulika, Seyfried, F., Docherty, N. G., Tremaroli, V., le Roux, C. W., Perkins, R. & Bäckhed, F., Sep 2017, In: I S M E Journal. 11, 9, p. 2035-2046 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Glucagon-like peptide-1 elicits vasodilation in adipose tissue and skeletal muscle in healthy men

Asmar, A., Asmar, M., Simonsen, L., Madsbad, Sten, Holst, Jens Juul, Hartmann, Bolette, Sorensen, Charlotte Mehlin & Bülow, J., Feb 2017, In: Physiological Reports. 5, 3, 12 p., e13073.

Research output: Contribution to journal › Journal article › Research › peer-review

The Gluco- and Liporegulatory and Vasodilatory Effects of Glucose-Dependent Insulinotropic Polypeptide (GIP) Are Abolished by an Antagonist of the Human GIP Receptor

Asmar, M., Asmar, A., Simonsen, L., Gasbjerg, Lærke Smidt, wbf943, wbf943, Rosenkilde, Mette, Hartmann, Bolette, Dela, Flemming, Holst, Jens Juul & Bülow, J., Sep 2017, In: Diabetes. 66, 9, p. 2363-2371 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Increased liver fat content in totally pancreatectomised patients

Bagger, J. I., Lund, A. B., Albrechtsen, Nicolai Jacob Wewer, Christensen, M., Grøndahl, M. F., Hansen, C. P., Storkholm, J., Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2017, In: Diabetologia. 60, S1, p. S572-S573

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

Regulation of glycolysis in brown adipocytes by HIF-1α

Basse, A. L., Isidor, Marie Sophie, Winther, Sally, Skjoldborg, N. B., Murholm, M., Andersen, E. S., Pedersen, S. B., Wolfrum, C., Quistorff, B. & Hansen, Jacob B., 22 Jun 2017, In: Scientific Reports. 7, 15 p., 4052.

Research output: Contribution to journal › Journal article › Research › peer-review

Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128·9 million children, adolescents, and adults

Bentham, J., Di Cesare, M., Bilano, V., Jørgensen, T., Linneberg, Allan René, Michaelsen, Kim F., Molbo, Drude, Mortensen, Erik Lykke, Osler, Merete, Sørensen, Thorkild I.A., Zhussupov, B., Zimmermann, E., Cisneros, J. Z., Damsgaard, Camilla Trab, Ängquist, Lars & NCD Risk Factor Collaboration (NCD-RisC), N. R. F. C. (., 2017, In: Lancet. 390, 10113, p. 2627-2642 16 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Pannexin-2-deficiency sensitizes pancreatic beta-cells to cytokine-induced apoptosis in vitro and impairs glucose tolerance in vivo

Berchtold, L. A., Miani, M., Diep, T. A., Madsen, A. N., Cigliola, V., Colli, M., Miskovic Krivokapic, Jelena, Pociot, Flemming, Eizirik, D. L., Meda, P., Holst, Birgitte, Billestrup, Nils & Storling, J., 2017, In: Molecular and Cellular Endocrinology. 448, p. 108-121 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Height at Ages 7-13 Years in Relation to Developing Type 2 Diabetes Throughout Adult Life

Bjerregaard, L. G., Jensen, B. W. & Baker, J. L., Jul 2017, In: Paediatric and Perinatal Epidemiology. 31, 4, p. 284-292 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Variations in the prevalence of obesity among european countries, and a consideration of possible causes

Blundell, J. E., Baker, J. L., Boyland, E., Blaak, E., Charzewska, J., De Henauw, S., Frühbeck, G., Gonzalez-Gross, M., Hebebrand, J., Holm, Lotte, Kriaucioniene, V., Lissner, L., Oppert, J. M., Schindler, K., Silva, A. M. & Woodward, E., 2017, In: Obesity Facts. 10, p. 25-37 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Does the sex of one's co-twin affect height and BMI in adulthood? A study of dizygotic adult twins from 31 cohorts

Bogl, L. H., Jelenkovic, A., Vuoksimaa, E., Ahrenfeldt, L., Pietiläinen, K. H., Stazi, M. A., Fagnani, C., D'Ippolito, C., Hur, Y-M., Jeong, H-U., Silberg, J. L., Eaves, L. J., Maes, H. H., Bayasgalan, G., Narandalai, D., Cutler, T. L., Kandler, C., Jang, K. L., Christensen, K., Skytthe, A. & 56 others, Kyvik, K. O., Cozen, W., Hwang, A. E., Mack, T. M., Derom, C. A., Vlietinck, R. F., Nelson, T. L., Whitfield, K. E., Corley, R. P., Huibregtse, B. M., McAdams, T. A., Eley, T. C., Gregory, A. M., Krueger, R. F., McGue, M., Pahlen, S., Willemsen, G., Bartels, M., van Beijsterveldt, T. C. E. M., Pang, Z., Tan, Q., Zhang, D., Martin, N. G., Medland, S. E., Montgomery, G. W., Hjelmborg, J. V. B., Rebato, E., Swan, G. E., Krasnow, R., Busjahn, A., Lichtenstein, P., Öncel, S. Y., Aliev, F., Baker, L. A., Tuvblad, C., Siribaddana, S. H., Hotopf, M., Sumathipala, A., Rijsdijk, F., Magnusson, P. K. E., Pedersen, N. L., Aslan, A. K. D., Ordoñana, J. R., Sánchez-Romera, J. F., Colodro-Conde, L., Duncan, G. E., Buchwald, D., Tarnoki, A. D., Tarnoki, D. L., Yokoyama, Y., Hopper, J. L., Loos, R. J. F., Boomsma, D. I., Sørensen, Thorkild I.A., Silventoinen, K. & Kaprio, J., 2017, In: Biology of Sex Differences. 8, 12 p., 14.

Research output: Contribution to journal › Journal article › Research › peer-review

Variable reliability of surrogate measures of insulin sensitivity after Roux-en-Y gastric bypass

Bojsen-Møller, K. N., Dirksen, C., Svane, M. S., Jørgensen, N. B., Holst, Jens Juul, Richter, Erik A. & Madsbad, Sten, 2017, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 312, 5, p. R797-R805 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Abscisic acid controls the release of insulin from beta-cells, Glucagon-Like Peptide-1 from intestinal L-cells and glucagon from alpha-cells

Booz, V., Christiansen, Charlotte Bayer, Kuhre, Rune Ehrenreich, Saltiel, M. Y., Sturla, L., Sociali, G., Zocchi, E., Holst, Jens Juul & Bruzzone, S., 2017, In: European Journal of Clinical Investigation. 47, p. 112-113

Research output: Contribution to journal › Conference abstract in journal › Research

The KDM5 family is required for activation of pro-proliferative cell cycle genes during adipocyte differentiation

Brier, A. B., Loft, A., Madsen, J. G. S., Rosengren, T., Nielsen, R., Schmidt, S. F., Liu, Z., Yan, Q., Gronemeyer, H. & Mandrup, S., 28 Feb 2017, In: Nucleic Acids Research. 45, 4, p. 1743-1759 17 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Metformin potentiates bile acid-induced GLP-1 secretion in patients with type 2 diabetes

Bronden, A., Alber, A., Rohde, U., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2017, In: Diabetologia. 60, p. 113-113 242.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

Clinical Pharmacokinetics and Pharmacodynamics of Albiglutide

Brønden, A., Knop, Filip Krag & Christensen, Mikkel Bring, 2017, In: Clinical Pharmacokinetics. 56, 7, p. 719-731

Research output: Contribution to journal › Review › Research › peer-review

Single-Dose Metformin Enhances Bile Acid-Induced Glucagon-Like Peptide-1 Secretion in Patients With Type 2 Diabetes

Brønden, A., Albér, A., Rohde, U., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Nov 2017, In: The Journal of clinical endocrinology and metabolism. 102, 11, p. 4153-4162 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Selection in Europeans on fatty acid desaturases associated with dietary changes

Buckley, M. T., Racimo, Fernando, Allentoft, Morten Erik, Jensen, M. K., Jonsson, Anna Elisabet, Huang, H., Hormozdiari, F., Sikora, Martin, Marnetto, D., Eskin, E., Jørgensen, M. E., Grarup, N., Pedersen, Oluf Borbye, Hansen, Torben, Kraft, P., Willerslev, Eske & Nielsen, Rasmus, Jun 2017, In: Molecular Biology and Evolution. 34, 6, p. 1307-1318 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

DPP4 gene variation affects GLP-1 secretion, insulin secretion, and glucose tolerance in humans with high body adiposity

Böhm, A., Wagner, R., Machicao, F., Holst, Jens Juul, Gallwitz, B., Stefan, N., Fritsche, A., Häring, H. & Staiger, H., 2017, In: PloS one. 12, 7, 13 p., e0181880.

Research output: Contribution to journal › Journal article › Research › peer-review

A molecular census of arcuate hypothalamus and median eminence cell types

Campbell, J. N., Macosko, E. Z., Fenselau, H., Pers, Tune H, Lyubetskaya, A., Tenen, D., Goldman, M., Verstegen, A. M. J., Resch, J. M., McCarroll, S. A., Rosen, E. D., Lowell, B. B. & Tsai, L. T., Mar 2017, In: Nature Neuroscience. 20, 3, p. 484-496 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Mechanism by which arylamine N-acetyltransferase 1 ablation causes insulin resistance in mice

Camporez, J. P., Wang, Y., Faarkrog, K., Chukijrungroat, N., Petersen, K. F. & Shulman, G. I., Dec 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 52, p. E11285-E11292 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Colonic infusions of short-chain fatty acid mixtures promote energy metabolism in overweight/obese men: a randomized crossover trial

Canfora, E. E., van der Beek, C. M., Jocken, J. W. E., Goossens, G. H., Holst, Jens Juul, Olde Damink, S. W. M., Lenaerts, K., Dejong, C. H. C. & Blaak, E. E., 24 May 2017, In: Scientific Reports. 7, 12 p., 2360.

Research output: Contribution to journal › Journal article › Research › peer-review

Supplementation of Diet With Galacto-oligosaccharides Increases Bifidobacteria, but Not Insulin Sensitivity, in Obese Prediabetic Individuals

Canfora, E. E., van der Beek, C. M., Hermes, G. D. A., Goossens, G. H., Jocken, J. W. E., Holst, Jens Juul, van Eijk, H. M., Venema, K., Smidt, H., Zoetendal, E. G., Dejong, C. H. C., Lenaerts, K. & Blaak, E. E., Jul 2017, In: Gastroenterology. 153, 1, p. 87-97.e3

Research output: Contribution to journal › Journal article › Research › peer-review

Postmenopausal hormone therapy and risk of stroke: A pooled analysis of data from population-based cohort studies

Carrasquilla, Germán D., Frumento, P., Berglund, A., Borgfeldt, C., Bottai, M., Chiavenna, C., Eliasson, M., Engstrom, G., Hallmans, G., Jansson, J., Magnusson, P. K., Nilsson, P. M., Pedersen, N. L., Wolk, A. & Leander, K., Nov 2017, In: PLoS Medicine. 14, 11

Research output: Contribution to journal › Journal article › Research › peer-review

DNA methylation changes at infertility genes in newborn twins conceived by in vitro fertilisation

Castillo-Fernandez, J. E., Loke, Y. J., Bass-Stringer, S., Gao, F., Xia, Y., Wu, H., Lu, H., Liu, Y., Wang, J., Spector, T. D., Saffery, R., Craig, J. M. & Bell, J. T., 24 Mar 2017, In: Genome Medicine. 9, 15 p., 28.

Research output: Contribution to journal › Journal article › Research › peer-review

¹H MRS Assessment of Hepatic Fat Content. Comparison Between Normal- and Excess-weight Children and Adolescents

Chabanova, E., Fonvig, Cilius Esmann, Bøjsøe, C., Holm, Jens-Christian & Thomsen, Henrik S., Aug 2017, In: Academic Radiology. 24, 8, p. 982-987 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

A functional IFN-λ4-generating DNA polymorphism could protect older asthmatic women from aeroallergen sensitization and associate with clinical features of asthma

Chinnaswamy, S., Wardzynska, A., Pawelczyk, M., Makowska, J., Skaaby, T., Mercader, J. M., Ahluwalia, T. S., Grarup, N., Guindo-Martinez, M., Bisgaard, H., Torrents, D., Linneberg, Allan René, Bønnelykke, Klaus & Kowalski, M. L., 5 Sep 2017, In: Scientific Reports. 7, 1, p. 1-11 11 p., 10500.

Research output: Contribution to journal › Journal article › Research › peer-review

Instrumentalization of eating improves weight loss maintenance in obesity

Christensen, Bodil Just, Iepsen, E. P. W., Lundgren, J. R., Holm, Lotte, Madsbad, Sten, Holst, Jens Juul & Torekov, Signe Sørensen, 2017, In: Obesity Facts. 10, 6, p. 633-647 15 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Overexpression of protein kinase STK25 in mice exacerbates ectopic lipid accumulation, mitochondrial dysfunction and insulin resistance in skeletal muscle

Chursa, U., Nuñez-Durán, E., Cansby, E., Amrutkar, M., Sütt, S., Ståhlman, M., Olsson, B., Borén, J., Johansson, M. E., Bäckhed, G. F., Johansson, B. R., Sihlbom, C. & Mahlapuu, M., Mar 2017, In: Diabetologia. 60, 3, p. 553-567 15 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Robust GLP-1 secretion by basic L-amino acids does not require the GPRC6A receptor

Clemmensen, Christoffer, Jørgensen, C. V., Smajilovic, S. & Bräuner, Hans, 2017, In: Diabetes, Obesity and Metabolism. 19, 4, p. 599-603

Research output: Contribution to journal › Journal article › Research › peer-review

Critical role for GLP-1 in symptomatic post-bariatric hypoglycaemia

Craig, C. M., Liu, L., Deacon, Carolyn F., Holst, Jens Juul & McLaughlin, T. L., Mar 2017, In: Diabetologia. 60, 3, p. 531-540

Research output: Contribution to journal › Journal article › Research › peer-review

Ponderal index at birth associates with later risk of gestational diabetes mellitus

Crusell, Mie Korslund Wiinblad, Damm, Peter, Hansen, Torben, Pedersen, Oluf Borbye, Glümer, C., Vaag, Allan & Lauenborg, J., Aug 2017, In: Archives of Gynecology and Obstetrics. 296, 2, p. 249-256 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Subclinical Hypothyroidism in Danish Lean and Obese Children and Adolescents

Dahl, M., Ohrt, J. D., Fonvig, C. E., Kloppenborg, J. T., Pedersen, Oluf Borbye, Hansen, Torben & Holm, Jens-Christian, 1 Mar 2017, In: JCRPE Journal of Clinical Research in Pediatric Endocrinology. 9, 1, p. 8-16 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Cardiovascular safety and benefits of GLP-1 receptor agonists

Dalsgaard, N. B., Brønden, A., Vilsbøll, Tina & Knop, Filip Krag, 2017, In: Expert Opinion on Drug Safety. 16, 3, p. 351-363 13 p.

Research output: Contribution to journal › Review › Research › peer-review

Acetylcholine-related proteins in non-neoplastic appearing colonic mucosa from patients with colorectal neoplasia

Damm, M. M. B., Jensen, T. S. R., Mahmood, B., Lundh, M., Poulsen, Steen Seier, Bindslev, Niels & Hansen, M. B., 2017, In: Molecular Carcinogenesis. 56, 10, p. 2223-2233 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Cohort description: The Danish study of Functional Disorders

Dantoft, T. M., Ebstrup, J. F., Linneberg, Allan René, Skovbjerg, S., Madsen, A. L., Mehlsen, J., Brinth, L., Eplov, L. F., Carstensen, T. W., Schroder, A., Fink, P. K., Mortensen, Erik Lykke, Hansen, Torben, Pedersen, Oluf Borbye & Jørgensen, T., Feb 2017, In: Clinical Epidemiology. 9, p. 127-139 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Biased agonism and allosteric modulation of GPR183- a 7TM receptor also known as EBV-induced EBI2

Daugvilaite, V., Madsen, C. M., Lückmann, Michael, Castello Echeverria, C., Sailer, A. W., Frimurer, Thomas Michael, Rosenkilde, Mette & Benned-Jensen, T., 2017, In: British Journal of Pharmacology. 174, 13, p. 2031–2042

Research output: Contribution to journal › Journal article › Research › peer-review

Abnormal epigenetic changes during differentiation of human skeletal muscle stem cells from obese subjects

Davegårdh, C., Broholm, C., Perfilyev, A., Henriksen, T., García-Calzón, S., Peijs, L., Hansen, N. S., Volkov, P., Kjøbsted, Rasmus, Wojtaszewski, Jørgen F P, Pedersen, M., Pedersen, Bente Klarlund, Ballak, D. B., Dinarello, C. A., Heinhuis, B., Joosten, L. A. B., Nilsson, E., Vaag, Allan, Schéele, Camilla Charlotte Nielsen & Ling, C., 2017, In: BMC Medicine. 15, 27 p., 39.

Research output: Contribution to journal › Journal article › Research › peer-review

ER Stress Inhibits Liver Fatty Acid Oxidation while Unmitigated Stress Leads to Anorexia-Induced Lipolysis and Both Liver and Kidney Steatosis

DeZwaan-McCabe, D., Sheldon, R. D., Gorecki, M. C., Guo, D., Gansemer, E. R., Kaufman, R. J., Rahmouni, K., Gillum, M. P., Taylor, E. B., Teesch, L. M. & Rutkowski, D. T., 30 May 2017, In: Cell Reports. 19, 9, p. 1794-1806 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Effects of liraglutide on cardiovascular risk factors in patients with type 1 diabetes

Dejgaard, T. F., Johansen, N. B., Frandsen, C. S. S., Asmar, A., Tarnow, L., Knop, Filip Krag, Madsbad, Sten & Andersen, H. U., May 2017, In: Diabetes, Obesity and Metabolism. 19, 5, p. 734–738

Research output: Contribution to journal › Letter › Research › peer-review

Dairy consumption, systolic blood pressure, and risk of hypertension: Mendelian randomization study

Ding, M., Huang, T., Bergholdt, H. K. M., Sørensen, Thorkild I.A., Linneberg, Allan René, Sandholt, C. H., Pedersen, Oluf Borbye, Hansen, Torben, Kilpeläinen, Tuomas O., CHARGE Consortium, C. C., Nordestgaard, Børge, Ellervik, Christina, Qi, L. & Mendelian Randomization of Dairy Consumption Working Group, M. R. O. D. C. W. G., 2017, In: The BMJ. 356, 10 p., j1000.

Research output: Contribution to journal › Journal article › Research › peer-review

Discovery, characterization, and clinical development of the glucagon-like peptides

Drucker, D. J., Habener, J. F. & Holst, Jens Juul, 1 Dec 2017, In: The Journal of Clinical Investigation. 127, 12, p. 4217-4227 11 p.

Research output: Contribution to journal › Review › Research › peer-review

Hepatocyte MyD88 affects bile acids, gut microbiota and metabolome contributing to regulate glucose and lipid metabolism

Duparc, T., Plovier, H., Marrachelli, V. G., Van Hul, M., Essaghir, A., Ståhlman, M., Matamoros, S., Geurts, L., Pardo-Tendero, M. M., Druart, C., Delzenne, N. M., Demoulin, J., van der Merwe, S. W., van Pelt, J., Bäckhed, G. F., Monleon, D., Everard, A. & Cani, P. D., 2017, In: Gut. 66, 4, p. 620-632 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

'No cognitive-enhancing effect of GLP-1 receptor agonism in antipsychotic-treated, obese patients with schizophrenia': authors' response

Ebdrup, Bjørn, Ishøy, P. L., Fagerlund, Birgitte, Broberg, B. V., Bak, N., Knop, Filip Krag & Glenthøj, Birte Yding, Nov 2017, In: Acta Psychiatrica Scandinavica. 136, 5, p. 526-527

Research output: Contribution to journal › Comment/debate › Research

Difference in postprandial GLP-1 response despite similar glucose kinetics after consumption of wheat breads with different particle size in healthy men

Eelderink, C., Noort, M. W. J., Sozer, N., Koehorst, M., Holst, Jens Juul, Deacon, Carolyn F., Rehfeld, Jens Frederik, Poutanen, K., Vonk, R. J., Oudhuis, L. & Priebe, M. G., 2017, In: European Journal of Nutrition. 56, 3, p. 1063-1076 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Histone deacetylase 3 prepares brown adipose tissue for acute thermogenic challenge

Emmett, M. J., Lim, H., Jager, J., Richter, H. J., Adlanmerini, M., Peed, L. C., Briggs, E. R., Steger, D. J., Ma, Tao, Sims, C. A., Baur, J. A., Pei, L., Won, K., Seale, P., Gerhart-Hines, Zach & Lazar, M. A., 2017, In: Nature Genetics. 546, 7659, p. 544-448

Research output: Contribution to journal › Journal article › Research › peer-review

Exercise modulates the aortic renin-angiotensin system independently of estrogen therapy in ovariectomized hypertensive rats

Endlich, P. W., Claudio, E. R. G., Lima, L. C. F., Ribeiro Júnior, R. F., Peluso, A. A. B., Stefanon, I., Bissoli, N. S., Lemos, V. S., Santos, R. A. S. D. & Abreu, G. R. D., 2017, In: Peptides.

Research output: Contribution to journal › Journal article › Research › peer-review

Homozygous carriers of the TCF7L2 rs7903146 T-allele show altered postprandial response in triglycerides and triglyceride-rich lipoproteins

pjx571, pjx571, Hansen, T. H., Mahendran, Y., Pyl, P., Galijatovic, E. A. A., Jonsson, Anna Elisabet, Gjesing, A., Linneberg, Allan René, Jørgensen, T., Hansen, Torben & drb459, drb459, 21 Feb 2017, In: Scientific Reports. 7, 8 p., 43128.

Research output: Contribution to journal › Journal article › Research › peer-review

Treatment with liraglutide may improve markers of CVD reflected by reduced levels of apoB

pjx571, pjx571, Lundgren, Jens, Albrechtsen, Nicolai Jacob Wewer, Mahendran, Y., Iepsen, E. P. W., Finocchietto, P., Jonsson, Anna Elisabet, Madsbad, Sten, Holst, Jens Juul, drb459, drb459, Hansen, Torben & Torekov, Signe Sørensen, 2017, In: Obesity Science & Practice. 3, 4, p. 425-433 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Causal relationship between obesity and serum testosterone status in men: A bi-directional mendelian randomization analysis

Eriksson, J., Haring, R., Grarup, N., Vandenput, L., Wallaschofski, H., Lorentzen, E., Hansen, Torben, Mellström, D., Pedersen, Oluf Borbye, Nauck, M., Lorentzon, M., Nystrup Husemoen, L. L., Völzke, H., Karlsson, M., Baumeister, S. E., Linneberg, Allan René & Ohlsson, C., 2017, In: PloS one. 12, 4, 15 p., e0176277.

Research output: Contribution to journal › Journal article › Research › peer-review

Interdependency of EGF and GLP-2 Signaling in Attenuating Mucosal Atrophy in a Mouse Model of Parenteral Nutrition

Feng, Y., Demehri, F. R., Xiao, W., Tsai, Y., Jones, J. C., Brindley, C. D., Threadgill, D. W., Holst, Jens Juul, Hartmann, Bolette, Barrett, T. A., Teitelbaum, D. H. & Dempsey, P. J., May 2017, In: Cellular and Molecular Gastroenterology and Hepatology. 3, 3, p. 447-468 22 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Data Descriptor: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

Flannick, J., Fuchsberger, C., Mahajan, A., Teslovich, T. M., Agarwala, V., Gaulton, K. J., Caulkins, L., Koesterer, R., Ma, C., Moutsianas, L., McCarthy, D. J., Rivas, M. A., Perry, J. R. B., Sim, X., Blackwell, T. W., Robertson, N. R., Rayner, N. W., Cingolani, P., Locke, A. E., Tajes, J. F. & 281 others, Highland, H. M., Dupuis, J., Chines, P. S., Lindgren, C. M., Hartl, C., Jackson, A. U., Chen, H., Huyghe, J. R., Van De Bunt, M., Pearson, R. D., Kumar, A., Müller-Nurasyid, M., Grarup, N., Stringham, H. M., Gamazon, E. R., Lee, J., Chen, Y., Scott, R. A., Below, J. E., Chen, P., Huang, J., Go, M. J., Stitzel, M. L., Pasko, D., Parker, S. C. J., V Varga, Tibor, Green, T., Beer, N. L., Day-Williams, A. G., Ferreira, T., Fingerlin, T., Horikoshi, M., Hu, C., Huh, I., Ikram, M. K., Kim, B. J., Kim, Y., Kim, Y. J., Kwon, M. S., Lee, J., Lee, S., Lin, K. H., Maxwell, T. J., Nagai, Y., Wang, X., Welch, R. P., Yoon, J., Zhang, W., Barzilai, N., Voight, B. F., Han, B. G., Jenkinson, C. P., Kuulasmaa, T., Kuusisto, J., Manning, A., Ng, M. C. Y., Palmer, N. D., Balkau, B., Stančáková, A., Abboud, H. E., Boeing, H., Giedraitis, V., Prabhakaran, D., Gottesman, O., Scott, J., Carey, J., Kwan, P., Grant, G., Smith, J. D., Neale, B. M., Purcell, S., Butterworth, A. S., Howson, J. M. M., Lee, H. M., Lu, Y., Kwak, S. H., Zhao, W., Danesh, J., Lam, V. K. L., Park, K. S., Saleheen, D., So, W. Y., Tam, C. H. T., Afzal, U., Aguilar, D., Arya, R., Aung, T., Chan, E., Navarro, C., Cheng, C. Y., Palli, D., Correa, A., Curran, J. E., Rybin, D., Farook, V. S., Fowler, S. P., Freedman, B. I., Griswold, M., Hale, D. E., Hicks, P. J., Khor, C. C., Kumar, S., Lehne, B., Thuillier, D., Lim, W. Y., Liu, J., Loh, M., Musani, S. K., Puppala, S., Scott, W. R., Yengo, L., Tan, S. T., Taylor, H. A., Thameem, F., Wilson, G., Wong, T. Y., Njølstad, P. R., Levy, J. C., Mangino, M., Bonnycastle, L. L., Schwarzmayr, T., Fadista, J., Surdulescu, G. L., Herder, C., Groves, C. J., Wieland, T., Bork-Jensen, J., Brandslund, I., Christensen, C., Koistinen, H. A., Doney, A. S. F., Kinnunen, L., Esko, T., Farmer, A. J., Hakaste, L., Hodgkiss, D., Kravic, J., Lyssenko, V., Hollensted, M., Jørgensen, M. E., Jørgensen, T., Ladenvall, C., Justesen, Johanne Marie, Käräjämäki, A., Kriebel, J., Rathmann, W., Lannfelt, L., Lauritzen, T., Narisu, N., Linneberg, Allan René, Melander, O., Milani, L., Neville, M., Orho-Melander, M., Qi, L., Qi, Q., Roden, M., Rolandsson, O., Swift, A., Rosengren, A. H., Stirrups, K., Wood, A. R., Mihailov, E., Blancher, C., Carneiro, M. O., Maguire, J., Poplin, R., Shakir, K., Fennell, T., DePristo, M., De Angelis, M. H., Deloukas, P., Gjesing, A. P., Jun, G., Nilsson, P. M., Murphy, J., Onofrio, R., Thorand, B., Hansen, Torben, Meisinger, C., Hu, F. B., Isomaa, B., Karpe, F., Liang, L., Peters, A., Huth, C., O'Rahilly, S. P., Palmer, C. N. A., Pedersen, Oluf Borbye, Rauramaa, R., Tuomilehto, J., Salomaa, V., Watanabe, R. M., Syvänen, A. C., Bergman, R. N., Bharadwaj, D., Bottinger, E. P., Cho, Y. S., Chandak, G. R., Chan, J. C. N., Chia, K. S., Daly, M. J., Ebrahim, S. B., Langenberg, C., Elliott, P., Jablonski, K. A., Lehman, D. M., Jia, W., Ma, R. C. W., Pollin, T. I., Sandhu, M., Tandon, N., Froguel, P., Barroso, I., Teo, Y. Y., Zeggini, E., Loos, Ruth, Small, K. S., Ried, J. S., DeFronzo, R. A., Grallert, H., Glaser, B., Metspalu, A., Wareham, N. J., Walker, M., Banks, E., Gieger, C., Ingelsson, E., Im, H. K., Illig, T., Franks, P. W., Buck, G., Trakalo, J., Buck, D., Prokopenko, I., Mägi, R., Lind, L., Farjoun, Y., Owen, K. R., Gloyn, A. L., Strauch, K., Tuomi, T., Kooner, J. S., Lee, J. Y., Park, T., Donnelly, P., Morris, A. D., Hattersley, A. T., Bowden, D. W., Collins, F. S., Atzmon, G., Chambers, J. C., Spector, T. D., Laakso, M., Strom, T. M., Bell, G. I., Blangero, J., Duggirala, R., Tai, E., McVean, G., Hanis, C. L., Wilson, J. G., Seielstad, M., Frayling, T. M., Meigs, J. B., Cox, N. J., Sladek, R., Lander, E. S., Gabriel, S., Mohlke, K. L., Meitinger, T., Groop, L., Abecasis, G., Scott, L. J., Morris, A. P., Kang, H. M., Altshuler, D., Burtt, N. P., Florez, J. C., Boehnke, M. & McCarthy, M. I., 19 Dec 2017, In: Scientific Data. 4, p. 1-20 20 p., 170179.

Research output: Contribution to journal › Journal article › Research › peer-review

Impact of gain-of-function mutations in the low-density lipoprotein receptor-related protein 5 (LRP5) on glucose and lipid homeostasis

Foer, D., Zhu, M., Cardone, R. L., Simpson, C., Sullivan, R., Nemiroff, S., Lee, G., Kibbey, R. G., Petersen, K. M. F. & Insogna, K. L., 10 Mar 2017, In: Osteoporosis International. 28, 6, p. 2011-17 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Nonalcoholic Fatty Liver Disease Is Prevalent in Women With Prior Gestational Diabetes Mellitus and Independently Associated With Insulin Resistance and Waist Circumference

Foghsgaard, S., Andreasen, C., Vedtofte, L., Andersen, E. S., Bahne, E., Strandberg, C., Buhl, T., Holst, Jens Juul, Svare, J. A., Clausen, Tine Dalsgaard, Mathiesen, Elisabeth, Damm, Peter, Gluud, Lise Lotte, Knop, Filip Krag & Vilsbøll, Tina, Jan 2017, In: Diabetes Care. 40, 1, p. 109-116 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Women with prior gestational diabetes mellitus and prediabetes are characterised by a decreased incretin effect

Foghsgaard, S., Vedtofte, L., Andreasen, C., Andersen, E. S., Bahne, E., Bagger, J. I., Svare, J. A., Holst, Jens Juul, Clausen, Tine Dalsgaard, Mathiesen, Elisabeth, Damm, Peter, Knop, Filip Krag & Vilsbøll, Tina, Jul 2017, In: Diabetologia. 60, 7, p. 1344-1353 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review