- 2017
- Published
Global hypomethylation is an independent prognostic factor in diffuse large B cell lymphoma
Wedge, E., Hansen, Jakob Werner, Garde, C., Asmar, F., Tholstrup, Dorte Maegaard, Kristensen, S. S., Munch-Petersen, H. D., Ralfkiaer, E., Brown, Peter de Nully, Grønbæk, Kirsten & Kristensen, L. S., Jul 2017, In: American Journal of Hematology. 92, 7, p. 689-694 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cross-Validation of a Glucose-Insulin-Glucagon Pharmacodynamics Model for Simulation Using Data From Patients With Type 1 Diabetes
Wendt, S. L., Ranjan, A., Møller, J. K., Schmidt, S., Knudsen, C. B., Holst, Jens Juul, Madsbad, Sten, Madsen, H., Nørgaard, Kirsten & Jørgensen, J. B., 1 Nov 2017, In: Journal of Diabetes Science and Technology. 11, 6, p. 1101-1111 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential impact of glucose administered intravenously or orally on bone turnover markers in healthy male subjects
Westberg-Rasmussen, S., Starup-Linde, J., Hermansen, K., Holst, Jens Juul, Hartmann, Bolette, Vestergaard, P. & Gregersen, S., Apr 2017, In: Bone. 97, p. 261-266 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A sandwich ELISA for measurement of the primary glucagon-like peptide-1 metabolite
Albrechtsen, Nicolai Jacob Wewer, Asmar, A., Jensen, F., Törang, S., Simonsen, L., Kuhre, Rune Ehrenreich, Asmar, M., Veedfald, Simon, Plamboeck, A., Knop, Filip Krag, Vilsbøll, Tina, Madsbad, Sten, Nauck, M. A., Deacon, Carolyn F., Bülow, J., Holst, Jens Juul & Hartmann, Bolette, 1 Sep 2017, In: American Journal of Physiology: Endocrinology and Metabolism. 313, 3, p. E284-E291Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Health care professionals from developing countries report educational benefits after an online diabetes course
Albrechtsen, Nicolai Jacob Wewer, Poulsen, K. W., Svensson, L. Ø., Jensen, Lasse X, Holst, Jens Juul & Torekov, Signe Sørensen, 31 May 2017, In: B M C Medical Education. 17, 8 p., 97.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Displaying the researched body: Growing cell portraits in a medical museum
Whiteley, Louise, Tybjerg, Karin & Pedersen, B. V., 1 Feb 2017, In: Leonardo & Leonardo Music Journal. 50, 1, p. 86-87 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exhibiting health and medicine as culture
Whiteley, Louise, Tybjerg, Karin, Pedersen, B. V., Bencard, Adam & Arnold, Ken, Mar 2017, In: Public Health Panorama. 3, 1, p. 59-68 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Parent perspectives on biomarkers for OCD: Talking of difficult presents, desired pasts, and imagined futures
Whiteley, Louise, Borgelt, E. L., Stewart, S. E. & Illes, J., Dec 2017, In: BioSocieties. 12, 4, p. 471–493 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Putting the brain in its place
Whiteley, Louise, 7 Jul 2017, In: Times Higher Education. p. 42-43 2 p.Research output: Contribution to journal › Literature review › Communication
- Published
‘The house’ as a framing device for public engagement in STEM museums
Whiteley, Louise, Stenslund, A., Arnold, Ken & Söderqvist, Thomas, Jul 2017, In: Museum & Society. 15, 2, p. 217-235 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness
Willems, S. M., et al., E. A., Grarup, N., Linneberg, Allan René, Schnurr, T. M., Pedersen, Oluf Borbye, GEFOS Any-Type of Fracture Consortium, G. A. O. F. C. & Hansen, Torben, 12 Jul 2017, In: Nature Communications. 8, 12 p., 16015.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Why is it so difficult to measure glucagon-like peptide-1 in a mouse?
Windeløv, Johanne Agerlin, Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Jepsen, Sara Lind, Hornburg, D., Pedersen, Jens, Jensen, E. P., Galsgaard, Katrine Douglas, Winther-Sørensen, Marie, Ørgaard, A., Deacon, Carolyn F., Mann, Matthias, Kissow, Hannelouise, Hartmann, Bolette & Holst, Jens Juul, Oct 2017, In: Diabetologia. 60, 10, p. 2066-2075 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Genome-Wide Association Study of IVGTT-Based Measures of First Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants
Wood, A. R., Jonsson, A., Jackson, A. U., Wang, T-N., van Leewen, N., Palmer, N. D., Kobes, S., Deelen, J., Boquete-Vilarino, L., Paananen, J., Stančáková, A., Boomsma, D. I., de Geus, E. J., Eekhoff, E. M., Fritsche, A., Kramer, M., Nijpels, G., Simonis-Bik, A. M. C., van Haeften, T. W., Mahajan, A. & 31 others, , 2017, In: Diabetes. 66, 8, p. 2296-2309Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug
Wu, H., Esteve, E., Tremaroli, V., Khan, M. T., Caesar, R., Mannerås-Holm, L., Ståhlman, M., Olsson, L. M., Serino, M., Planas-Fèlix, M., Xifra, G., Mercader, J. M., Torrents, D., Burcelin, R., Ricart, W., Perkins, R., Fernàndez-Real, J. M. & Bäckhed, F., Jul 2017, In: Nature Medicine. 23, 7, p. 850-858 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-fat feeding rather than obesity drives taxonomical and functional changes in the gut microbiota in mice
Xiao, L., Sonne, S. B., Feng, Q., Chen, N., Xia, Z., Li, X., Fang, Z., Zhang, D., Fjære, E., Midtbø, L. K., Derrien, M., Hugenholtz, F., Tang, L., Li, J., Zhang, J., Liu, C., Hao, Q., Vogel, U. B., Mortensen, A., Kleerebezem, M. & 8 others, , 8 Apr 2017, In: Microbiome. 5, 12 p., 43.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preserved glucagon-like peptide-1 responses to oral glucose, but reduced incretin effect, insulin secretion and sensitivity in young Asians with type 2 diabetes mellitus
Yeow, T. P., Pacini, G., Tura, A., Hor, C. P., Lim, S. L., Tan, F. H. S., Tong, C. V., Hong, J. Y. H., Md Zain, F., Holst, Jens Juul & Wan Mohamud, W. N., 2017, In: BMJ open diabetes research & care. 5, 1, 9 p., e000352.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metagenomic analysis of faecal microbiome as a tool towards targeted non-invasive biomarkers for colorectal cancer
Yu, J., Feng, Q., Wong, S. H., Zhang, D., Liang, Q. Y., Qin, Y., Tang, L., Zhao, H., Stenvang, J., Li, Y., Wang, X., Xu, X., Chen, N., Wu, W. K. K., Al-Aama, J., Nielsen, H. J., Kiilerich, P., Jensen, B. A. H., Yau, T. O., Lan, Z. & 19 others, , 2017, In: Gut. 66, p. 70-78 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Signaling Pathways as Potential Therapeutic Targets in Hepatocarcinogenesis
Yılmaz, Y., Güneş, A., Topel, Hande & Atabey, N., Sep 2017, In: Journal of Gastrointestinal Cancer. 48, 3, p. 225-237 13 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Environmental spread of microbes impacts the development of metabolic phenotypes in mice transplanted with microbial communities from humans
Zhang, L., Bahl, M. I., Roager, Henrik Munch, Fonvig, C. E., Hellgren, L. I., Frandsen, H. L., Pedersen, Oluf Borbye, Holm, Jens-Christian, Hansen, Torben & Licht, T. R., 18 Nov 2017, In: The ISME Journal. 11, p. 676-690 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease
Zhao, W., Rasheed, A., Tikkanen, E., Lee, J-J., Butterworth, A. S., Howson, J. M. M., Assimes, T. L., Chowdhury, R., Orho-Melander, M., Damrauer, S., Small, A., Asma, S., Imamura, M., Yamauch, T., Chambers, J. C., Chen, P., Sapkota, B. R., Shah, N., Jabeen, S., Surendran, P. & 31 others, , Oct 2017, In: Nature Genetics. 49, 10, p. 1450-1457 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Large meta-analysis of genome-wide association studies identifies five loci for lean body mass
Zillikens, M. C., Demissie, S., Hsu, Y-H., Yerges-Armstrong, L. M., Chou, W-C., Stolk, L., Livshits, G., Broer, L., Johnson, T., Koller, D. L., Kutalik, Z., Luan, J., Malkin, I., Ried, J. S., Smith, A. V., Thorleifsson, G., Vandenput, L., Hua Zhao, J., Zhang, W., Aghdassi, A. & 173 others, , 19 Jul 2017, In: Nature Communications. 8, 13 p., 80.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Childhood body mass index and development of type 2 diabetes throughout adult life: A large-scale danish cohort study
Zimmermann, E., Bjerregaard, L. G., Gamborg, M., Vaag, Allan, Sørensen, Thorkild I.A. & Baker, J. L., 2017, In: Obesity. 25, 5, p. 965-971Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study
de Vries, P. S., Sabater-Lleal, M., Chasman, D. I., Trompet, S., Ahluwalia, T. S., Teumer, A., Kleber, M. E., Chen, M-H., Wang, J. J., Attia, J. R., Marioni, R. E., Steri, M., Weng, L-C., Pool, R., Grossmann, V., Brody, J. A., Venturini, C., Tanaka, T., Rose, L. M., Oldmeadow, C. & 66 others, , 2017, In: PLOS ONE. 12, 1, 22 p., e0167742.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Discovery of novel heart rate-associated loci using the Exome Chip
van den Berg, M. E., Warren, H. R., Cabrera, C. P., Verweij, N., Mifsud, B., Haessler, J., Bihlmeyer, N. A., Fu, Y-P., Weiss, S., Lin, H. J., Grarup, N., Li-Gao, R., Pistis, G., Shah, N., Brody, J. A., Müller-Nurasyid, M., Lin, H., Mei, H., Smith, A. V., Lyytikäinen, L-P. & 101 others, , 15 Jun 2017, In: Human Molecular Genetics. 26, 12, p. 2346-2363 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of somatostatin in GLP-1-induced inhibition of glucagon secretion in mice
Ørgaard, A. & Holst, Jens Juul, Sep 2017, In: Diabetologia. 60, 9, p. 1731-1739 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
In vivo characterization of the ultrapotent monoacylglycerol lipase inhibitor {4-[bis-(benzo[d][1,3]dioxol-5-yl)methyl]-piperidin-1-yl}(1H-1,2,4-triazol-1-yl)methanone (JJKK-048)
Aaltonen, N., Kedzierska, E., Orzelska-Górka, J., Lehtonen, M., Navia-Paldanius, D., Jakupovic, Hermina, Savinainen, J. R., Nevalainen, T., Laitinen, J. T., Parkkari, T. & Gynther, M., Oct 2016, In: Journal of Pharmacology and Experimental Therapeutics. 359, 1, p. 62-72 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tracking of body mass index from 7 to 69 years of age
Aarestrup, J., Bjerregaard, L. G., Gamborg, Michael Orland, Ängquist, Lars, Tjønneland, Anne, Overvad, K., Linneberg, Allan René, Osler, Merete, Mortensen, Erik Lykke, Gyntelberg, F., Lund, Rikke, Sørensen, Thorkild I.A. & Baker, J. L., Sep 2016, In: International Journal of Obesity. 40, 9, p. 1376-1383 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Childhood body mass index and height and risk of histologic subtypes of endometrial cancer
Aarestrup, J., Gamborg, Michael Orland, Ulrich, L. G., Sørensen, Thorkild I.A. & Baker, J. L., 2016, In: International Journal of Obesity. 40, p. 1096-1102 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcriptomic profiling of pancreatic alpha, beta and delta cell populations identifies delta cells as a principal target for ghrelin in mouse islets
Adriaenssens, A. E., Svendsen, B., Lam, B. Y. H., Yeo, G. S. H., Holst, Jens Juul, Reimann, F. & Gribble, F. M., Oct 2016, In: Diabetologia. 59, 10, p. 2156-2165 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
BODY MASS INDEX AND MORTALITY OVER 3 DECADES
Afzal, Shoaib, Tybjærg-Hansen, Anne, Jensen, G. B. & Nordestgaard, Børge, Sep 2016, In: Atherosclerosis. 252, p. E222-E222 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Dynamics of glucagon secretion in mice and rats revealed using a validated sandwich ELISA for small sample volumes.
Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Windeløv, Johanne Agerlin, Ørgaard, A., Deacon, Carolyn F., Kissow, Hannelouise, Hartmann, Bolette & Holst, Jens Juul, 2016, In: American Journal of Physiology: Endocrinology and Metabolism. 311, 2, p. E302-E309 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1 receptor signaling in acinar cells causes growth dependent release of pancreatic enzymes
Albrechtsen, Nicolai Jacob Wewer, Albrechtsen, Reidar, Bremholm, L., Svendsen, B., Kuhre, Rune Ehrenreich, Poulsen, Steen Seier, Christiansen, Charlotte Bayer, Jensen, E. P., Janus, C., Hilsted, Linda, Deacon, Carolyn F., Hartmann, Bolette & Holst, Jens Juul, 2016, In: Cell Reports. 17, 11, p. 2845-2856 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The intestinal distribution pattern of appetite- and glucose regulatory peptides in mice, rats and pigs
Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Toräng, S. & Holst, Jens Juul, 2 Feb 2016, In: BMC Research Notes. 9, 1, p. 1-6 6 p., 60.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inflammatory biomarkers and risk of cancer in 84,000 individuals from the general population
Allin, K. H., Bojesen, Stig Egil & Nordestgaard, Børge, 1 Oct 2016, In: International Journal of Cancer. 139, 7, p. 1493-500 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Obstructive sleep apnea in obese children and adolescents, treatment methods and outcome of treatment: A systematic review
Andersen, I. G., Holm, Jens-Christian & Homøe, Preben, Aug 2016, In: International Journal of Pediatric Otorhinolaryngology. 87, p. 190-7 8 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Genetics of Type 2 diabetes: the power of isolated populations
Lepola, Mette Andersen, Pedersen, C. T., Moltke, Ida, Hansen, Torben, Albrechtsen, Anders & Grarup, N., 2016, In: Current Diabetes Reports. 16, 7, 9 p., 65.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of novel genetic determinants of erythrocyte membrane fatty acid composition among Greenlanders
Lepola, Mette Andersen, Jørsboe, E., Sandholt, C. H., Grarup, N., Jørgensen, M. E., Færgeman, N. J., Bjerregaard, P., Pedersen, Oluf Borbye, Moltke, Ida, Hansen, Torben & Albrechtsen, Anders, 2016, In: P L o S Genetics. 12, 6, 19 p., e1006119.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The gut microbiota and metabolic disease: current understanding and future perspectives
Arora, T. & Bäckhed, G. F., Oct 2016, In: Journal of Internal Medicine. 280, 4, p. 339-49 11 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Microbially produced glucagon-like peptide 1 improves glucose tolerance in mice
Arora, T., Wegmann, U., Bobhate, A., Lee, Y. S., Greiner, T. U., Drucker, D. J., Narbad, A. & Bäckhed, G. F., Aug 2016, In: Molecular Metabolism. 5, 8, p. 725-30 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1 does not have acute effects on central or renal hemodynamics in patients with type 2 diabetes without nephropathy
Asmar, A., Simonsen, L., Asmar, M., Madsbad, Sten, Holst, Jens Juul, Frandsen, E., Moro, C., Sorensen, Charlotte Mehlin, Jonassen, Thomas & Bulow, J., May 2016, In: American Journal of Physiology: Endocrinology and Metabolism. 310, 9, p. E744-E753 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The blunted effect of glucose-dependent insulinotropic polypeptide in subcutaneous abdominal adipose tissue in obese subjects is partly reversed by weight loss
Asmar, M., Arngrim, N., Simonsen, L., Asmar, A., Nordby, P., Holst, Jens Juul & Bülow, J., 2016, In: Nutrition and Diabetes. 6, 7 p., e208.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulin Plays a Permissive Role for the Vasoactive Effect of GIP Regulating Adipose Tissue Metabolism in Humans
Asmar, M., Simonsen, L., Asmar, Ali, Holst, Jens Juul, Dela, Flemming & Bülow, J., Aug 2016, In: Journal of Clinical Endocrinology and Metabolism. 101, 8, p. 3155-62 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stress hormone release is a key component of the metabolic response to lipopolysaccharide (LPS): studies in hypopituitary and healthy subjects
Bach, E., Møller, A. B., Jorgensen, J. O. L., Vendelbo, M. H., Jessen, N., Pedersen, S. B., Nielsen, Thomas Svava & Møller, N., 25 Aug 2016, In: European Journal of Endocrinology. 175, 5, p. 455-465 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Iron Regulation of Pancreatic Beta-Cell Functions and Oxidative Stress
Backe, M. B., Moen, I. W., Ellervik, Christina, Hansen, J. B. & Mandrup-Poulsen, Thomas, 17 Jul 2016, In: Annual Review of Nutrition. 36, p. 241-273 33 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Blood-based biomarkers of age-associated epigenetic changes in human islets associate with insulin secretion and diabetes
Bacos, K., Gillberg, L., Volkov, P., Olsson, A. H., Hansen, Torben, Pedersen, Oluf Borbye, Gjesing, A. M. P., Eiberg, Hans Rudolf Lytchoff, Tuomi, T., Almgren, P., Groop, L., Eliasson, L., Vaag, Allan, Dayeh, T. & Ling, C., 2016, In: Nature Communications. 7, 13 p., 11089.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An Improved Method for High Quality Metagenomics DNA Extraction from Human and Environmental Samples
Bag, S., Saha, B., Mehta, O., Anbumani, D., Kumar, N., Dayal, M., Pant, A., Kumar, P., Saxena, S., Allin, K. H., Hansen, T., Arumugam, M., Vestergaard, H., Pedersen, O., Pereira, V., Abraham, P., Tripathi, R., Wadhwa, N., Bhatnagar, S., Prakash, V. G. & 7 others, , 2016, In: Scientific Reports. 6, 9 p., 26775.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Involvement of glucagon-like peptide-1 in the glucose-lowering effect of metformin
Bahne, E., Hansen, M., Brønden, A., Sonne, David Peick, Vilsbøll, Tina & Knop, Filip Krag, Oct 2016, In: Diabetes, Obesity and Metabolism Online. 18, 10, p. 955-61 7 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Differential regulation of lipid and protein metabolism in obese vs. lean subjects before and after a 72-h fast
Bak, A. M., Møller, A. B., Vendelbo, M. H., Nielsen, Thomas Svava, Viggers, R., Rungby, Jørgen, Pedersen, S. B., Jørgensen, J. O. L., Jessen, N. & Møller, N., 1 Jul 2016, In: American Journal of Physiology: Endocrinology and Metabolism. 311, 1, p. E224-35 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Excessive gains in BMI during adolescence increase risks of cardiovascular mortality in men
Baker, J. L., Dec 2016, In: The Lancet Diabetes & Endocrinology. 4, 12, p. 964-966 3 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Feedback suppression of meal-induced glucagon-like peptide-1 (GLP-1) secretion mediated through elevations in intact GLP-1 caused by dipeptidyl peptidase-4 inhibition: a randomized, prospective comparison of sitagliptin and vildagliptin treatment
Baranov, O., Kahle, M., Deacon, Carolyn F., Holst, Jens Juul & Nauck, M. A., Nov 2016, In: Diabetes, Obesity and Metabolism. 18, 11, p. 1100-1109 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide analysis identifies 12 loci influencing human reproductive behavior
Barban, N., Jansen, R., de Vlaming, R., Vaez, A., Mandemakers, J. J., Tropf, F. C., Shen, X., Wilson, J. F., Chasman, D. I., Nolte, I. M., Tragante, V., van der Laan, S. W., Perry, J. R. B., Kong, A., Ahluwalia, T. V. S., Albrecht, E., Yerges-Armstrong, L., Atzmon, G., Auro, K., Ayers, K. & 31 others, , Dec 2016, In: Nature Genetics. 48, 12, p. 1462-1472 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of Conserved Disulfide Bridges and Aromatic Residues in Extracellular Loop 2 of Chemokine Receptor CCR8 for Chemokine and Small Molecule Binding
Barington, L., Rummel, P. C., Lückmann, Michael, Pihl, H., Larsen, Olav, Daugvilaite, V., Johnsen, A. H., Frimurer, Thomas Michael, Karlshøj, S. & Rosenkilde, Mette, 19 May 2016, In: The Journal of Biological Chemistry. 291, 31, p. 16208-16220Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The legacy of our ancestors' lifestyle
Barrès, Romain, 2016, In: Biochemist. 38, 2, p. 1-4 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of diet and exercise in the transgenerational epigenetic landscape of T2DM
Barrès, Romain & Zierath, Juleen R, Aug 2016, In: Nature Reviews Endocrinology. 12, 8, p. 441-51 11 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Alle mulige vilde ting: Et nedslag i ny materialitetsfilosofi
Bencard, Adam, 2016, In: Passepartout. 37, p. 35-49 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mutations causative of familial hypercholesterolaemia: screening of 98 098 individuals from the Copenhagen General Population Study estimated a prevalence of 1 in 217
Benn, M., Watts, G. F., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 1 May 2016, In: European Heart Journal. 37, 17, p. 1384-94 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of kisspeptin and RFRP in the circadian control of female reproduction
Beymer, M., Henningsen, J., Bahougne, T. & Simonneaux, V., 15 Dec 2016, In: Molecular and Cellular Endocrinology. 438, p. 89-99 11 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Childhood height, adult height, and the risk of prostate cancer
Bjerregaard, L. G., Aarestrup, J., Gamborg, Michael Orland, Lange, Theis, Tjønneland, A. & Baker, J. L., Apr 2016, In: Cancer Causes & Control. 27, 4, p. 561-567 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of Pre-Pregnancy Body Mass Index, Pregnancy-Related Weight Changes, and Parity With the Risk of Developing Degenerative Musculoskeletal Conditions
Bliddal, M., Pottegård, A., Kirkegaard, H., Olsen, J., Jørgensen, J. S., Sørensen, Thorkild I.A., Dreyer, L. & Nohr, E. A., May 2016, In: Arthritis & Rheumatism. 68, 5, p. 1156-64 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Depressive symptoms in women's midlife in relation to their body weight before, during and after childbearing years
Bliddal, M., Pottegård, A., Kirkegaard, H., Olsen, J., Sørensen, Thorkild I.A. & Nohr, E. A., Dec 2016, In: Obesity Science & Practice. 2, 4, p. 415-425 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Assessing the role of insulin-like growth factors and binding proteins in prostate cancer using Mendelian randomization: Genetic variants as instruments for circulating levels
Bonilla, C., Lewis, S. J., Rowlands, M-A., Gaunt, T. R., Davey-Smith, G., Gunnell, D., Palmer, T. M., Donovan, J. L., Hamdy, F. C., Neal, D. E., Eeles, R., Easton, D., Kote-Jarai, Z., Al Olama, A. A., Benlloch, S., Muir, K., Giles, G., Wiklund, F., Grönberg, H., Haiman, C. A. & 22 others, , 1 Oct 2016, In: International Journal of Cancer. 139, 7, p. 1520-1533 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Epigenetic programming of adipose-derived stem cells in low birthweight individuals
Broholm, C., Olsson, A. H., Perfilyev, A., Hansen, N. S., Schrölkamp, M., Strasko, K. S., Schéele, Camilla Charlotte Nielsen, Ribel-Madsen, R., Mortensen, B., Jørgensen, S. W., Ling, C. & Vaag, Allan, 2016, In: Diabetologia. 59, 12, p. 2664-2673 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Digital questionnaire platform in the Danish Blood Donor Study
Burgdorf, K. S., Felsted, N., Mikkelsen, S., Nielsen, Maria Haahr, Thørner, L. W., Pedersen, Oluf Borbye, Sørensen, E., Nielsen, K. R., Bruun, M. T., Werge, Thomas, Erikstrup, C., Hansen, T. & Ullum, H., 12 Jul 2016, In: Computer Methods and Programs in Biomedicine. 135, p. 101-104 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multi-technique approach for qualitative and quantitative characterization of furazidin degradation kinetics under alkaline conditions
Bērziņš, Kārlis, Kons, A., Grante, I., Dzabijeva, D., Nakurte, I. & Actiņš, A., 2016, In: Journal of Pharmaceutical and Biomedical Analysis.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interaction between dietary lipids and gut microbiota regulates hepatic cholesterol metabolism
Caesar, R., Nygren, H., Orešič, M. & Bäckhed, G. F., Mar 2016, In: Journal of Lipid Research. 57, 3, p. 474-81 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evidence for L1-associated DNA rearrangements and negligible L1 retrotransposition in glioblastoma multiforme
Carreira, P. E., Ewing, A. D., Li, G., Schauer, S. N., Upton, K. R., Fagg, A. C., Morell, S., Kindlova, M., Gerdes, P., Richardson, S. R., Li, B., Gerhardt, D. J., Wang, J., Brennan, P. M. & Faulkner, G. J., 2016, In: Mobile D N A. 7, 14 p., 21.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exercise Promotes Healthy Aging of Skeletal Muscle
Cartee, G. D., Hepple, R. T., Bamman, M. M. & Zierath, Juleen R, 14 Jun 2016, In: Cell Metabolism. 23, 6, p. 1034-47 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Secretion of glucagon-like peptide-2 responds to nutrient intake but not glucose provision in milk-fed calves
Castro, J. J., Morrison, S. Y., Hosseinni, A., Loor, J. J., Drackley, J. K., Ipharraguerre, I. R., Holst, Jens Juul & Hartmann, Bolette, Jul 2016, In: Journal of Dairy Science. 99, 7, p. 5793–5807Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits
Chami, N., Chen, M-H., Slater, A. J., Eicher, J. D., Evangelou, E., Tajuddin, S. M., Love-Gregory, L., Kacprowski, T., Schick, U. M., Nomura, A., Giri, A., Lessard, S., Brody, J. A., Schurmann, C., Pankratz, N., Yanek, L. R., Manichaikul, A., Pazoki, R., Mihailov, E., Hill, W. D. & 93 others, , 7 Jul 2016, In: American Journal of Human Genetics. 99, 1, p. 8-21 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pregnancy and childhood exposure to residential traffic noise and overweight at 7 years of age
Christensen, J. S., Hjortebjerg, D., Raaschou-Nielsen, O., Ketzel, M., Sørensen, Thorkild I.A. & Sørensen, M., Sep 2016, In: Environment International. 94, 9, p. 170-176 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Road Traffic and Railway Noise Exposures and Adiposity in Adults: A Cross-Sectional Analysis of the Danish Diet, Cancer, and Health Cohort
Christensen, J. S., Raaschou-Nielsen, O., Tjønneland, A., Overvad, K., Nordsborg, R. B., Ketzel, M., Sørensen, Thorkild I.A. & Sørensen, M., Mar 2016, In: Environmental Health Perspectives. 124, 3, p. 329-35 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High BMI And Risk Of Exacerbations And Pneumonias In Individuals With COPD: Observational And Genetic Risk Estimates From The Copenhagen General Population Study
Colak, Y., Afzal, Shoaib, Lange, Peter & Nordestgaard, Børge, 2016, In: American Journal of Respiratory and Critical Care Medicine. 193, 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Getting from A to B-exploring the activation motifs of the class B adhesion G protein-coupled receptor subfamily G member 4/GPR112
Cornelia Peeters, M., Mos, I., Lenselink, E. B., Lucchesi, M., IJzerman, A. P. & Schwartz, Thue W., May 2016, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 30, 5, p. 1836-1848 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer
Couch, F. J., Kuchenbaecker, K. B., Michailidou, K., Mendoza-Fandino, G. A., Nord, S., Lilyquist, J., Olswold, C., Hallberg, E., Agata, S., Ahsan, H., Aittomäki, K., Ambrosone, C. B., Andrulis, I. L., Anton-Culver, H., Arndt, V., Arun, B. K., Arver, B., Barile, M., Barkardottir, R. B., Barrowdale, D. & 229 others, , 2016, In: Nature Communications. 7, p. 1-13 13 p., 11375.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of mineralocorticoid receptor antagonists on proteinuria and progression of chronic kidney disease: a systematic review and meta-analysis
Currie, G., Taylor, A. H. M., Fujita, T., Ohtsu, H., Lindhardt, M., Rossing, Peter, Boesby, L., Edwards, N. C., Ferro, C. J., Townend, J. N., van den Meiracker, A. H., Saklayen, M. G., Oveisi, S., Jardine, A. G., Delles, C., Preiss, D. J. & Mark, P. B., 2016, In: B M C Nephrology. 17, p. 1-14 14 p., 127.Research output: Contribution to journal › Review › Research › peer-review
- Published
A century of trends in adult human height
Damsgaard, Camilla Trab, Michaelsen, Kim F., Molbo, Drude, Mortensen, Erik Lykke, Sørensen, Thorkild I.A. & NCD Risk Factor Collaboration (NCD-RisC), N. R. F. C. (., 26 Jul 2016, In: eLife. 5, 29 p., e13410.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Trends in adult body-mass index in 200 countries from 1975 to 2014: A pooled analysis of 1698 population-based measurement studies with 19.2 million participants
Damsgaard, Camilla Trab, Michaelsen, Kim F., Molbo, Drude, Mortensen, Erik Lykke, Sørensen, Thorkild I.A. & NCD Risk Factor Collaboration (NCD-RisC), N. R. F. C. (., 2016, In: The Lancet. 387, 10026, p. 1377-1396 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Microbiota-Produced Succinate Improves Glucose Homeostasis via Intestinal Gluconeogenesis
De Vadder, F., Kovatcheva-Datchary, P., Zitoun, C., Duchampt, A., Bäckhed, G. F. & Mithieux, G., 12 Jul 2016, In: Cell Metabolism. 24, 1, p. 151-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparative review of dipeptidyl peptidase-4 inhibitors and sulphonylureas.
Deacon, Carolyn F. & Lebovitz, H., 2016, In: Diabetes, Obesity and Metabolism. 18, 4, p. 333-347 15 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
DPP-4 inhibitors
Deacon, Carolyn F., 2016, Handbook of incretin therapies in type 2 diabetes. Gough, S. (ed.). Switzerland: Springer, p. 45-60Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication
- Published
Efficacy and safety of liraglutide for overweight adult patients with type 1 diabetes and insufficient glycaemic control (Lira-1): a randomised, double-blind, placebo-controlled trial
Dejgaard, T. F., Frandsen, C. S., Hansen, T. S., Almdal, Thomas Peter, Urhammer, Søren Asger, Pedersen-Bjergaard, Ulrik, Jensen, T., Jensen, Andreas Kryger, Holst, Jens Juul, Tarnow, L., Knop, Filip Krag, Madsbad, Sten & Andersen, H. U., Mar 2016, In: The Lancet Diabetes & Endocrinology. 4, 3, p. 221–232 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Liraglutide for treating type 1 diabetes
Dejgaard, T. F., Frandsen, C. S., Holst, Jens Juul & Madsbad, Sten, Apr 2016, In: Expert Opinion on Biological Therapy. 16, 4, p. 579-90 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteomics of Skeletal Muscle: Focus on Insulin Resistance and Exercise Biology.
Deshmukh, Atul Shahaji, 4 Feb 2016, In: Proteomes.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No Islet Cell Hyperfunction, but Altered Gut-Islet Regulation and Postprandial Hypoglycemia in Glucose-Tolerant Patients 3 Years After Gastric Bypass Surgery
Dirksen, C., Eiken, A., Bojsen-Møller, K. N., Svane, M. S., Martinussen, C., Jørgensen, N. B., Holst, Jens Juul & Madsbad, Sten, Sep 2016, In: Obesity Surgery. 26, 9, p. 2263-7 5 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Epigenetisk påvirkning af fosterets udvikling
Donkin, I., Barrès, Romain & Pinborg, Anja, 12 Sep 2016, In: Ugeskrift for Laeger. 178, 37, p. 2-5 V02160132.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Obesity and Bariatric Surgery Drive Epigenetic Variation of Spermatozoa in Humans
Donkin, I., Versteyhe, S., Ingerslev, L. R., Qian, K., Mechta, Mie, Nordkap, L., Mortensen, B., Appel, E. V. R., Jørgensen, N., Kristiansen, V. B., Hansen, Torben, Workman, C. T., Zierath, Juleen R & Barrès, Romain, 9 Feb 2016, In: Cell Metabolism. 23, 2, p. 369-78 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Limited availability of childhood overweightand obesity treatment programmes in Danish paediatric departments
Eg, M., Cortes, Dina, Johansen, A., Frederiksen, K., Lorentzen, V., Larsen, L. M., Holm, Jens-Christian & Vámosi, M., Sep 2016, In: Danish Medical Journal. 63, 9, p. 1-5 5 p., A5269.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals
Ehret, G. B., Ferreira, T., Chasman, D. I., Jackson, A. U., Schmidt, E. M., Johnson, T., Thorleifsson, G., Luan, J., Donnelly, L. A., Kanoni, S., Petersen, A-K., Pihur, V., Strawbridge, R. J., Shungin, D., Hughes, M. F., Meirelles, O., Kaakinen, M., Bouatia-Naji, N., Kristiansson, K., Shah, S. & 31 others, , 12 Sep 2016, In: Nature Genetics. 48, 10, p. 1171-1184 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GPR119 - a major Enteroendocrine Sensor of Dietary Triglyceride Metabolites Co-acting in Synergy with FFA1 (GPR40)
Ekberg, J. H., Pedersen, M. H., Kristensen, L. V., Madsen, A. N., Engelstoft, M. S., Husted, Anna Sofie, Sichlau, R., Egerod, Kristoffer Lihme, Timshel, P., Kowalski, T. J., Gribble, F. M., Reiman, F., Hansen, Harald S., Howard, A. D., Holst, Birgitte & Schwartz, Thue W., 25 Oct 2016, In: Endocrinology. 157, 12, p. 4561-4569 9 p., en20161334.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci
Ellinghaus, D., Jostins, L., Spain, S. L., Cortes, A., Bethune, J., Han, B., Park, Y. R., Raychaudhuri, S., Pouget, J. G., Hübenthal, M., Folseraas, T., Wang, Y., Esko, T., Metspalu, A., Westra, H-J., Franke, L., Pers, T. H., Weersma, R. K., Collij, V., D'Amato, M. & 26 others, , May 2016, In: Nature Genetics. 48, 5, p. 510-521 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Weight loss and weight maintenance obtained with or without GLP-1 analogue treatment decrease branched chain amino acid levels
pjx571, pjx571, Iepsen, E. P. W., Galijatovic, E. A. A., Mahendran, Y., Lundgren, J. R., Jonsson, Anna Elisabet, Madsbad, Sten, Holst, Jens Juul, drb459, drb459, Hansen, Torben & Torekov, Signe Sørensen, Dec 2016, In: Metabolomics. 12, 12, p. 1-9 9 p., 181.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Opposite Regulation of Ghrelin and Glucagon-like Peptide-1 by Metabolite G-Protein-Coupled Receptors
Engelstoft, M. S. & Schwartz, Thue W., Sep 2016, In: Trends in Endocrinology and Metabolism. 27, 9, p. 665-675 11 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
15-year follow-up of the Second Nordic Mantle Cell Lymphoma trial (MCL2): prolonged remissions without survival plateau
Eskelund, C. W., Kolstad, A., Jerkeman, M., Räty, R., Laurell, A., Eloranta, S., Smedby, K. E., Husby, S., Pedersen, L. B., Andersen, N. S., Eriksson, M., Kimby, E., Bentzen, H., Kuittinen, O., Lauritzsen, G. F., Nilsson-Ehle, H., Ralfkiaer, E., Ehinger, M., Sundström, C., Delabie, J. & 7 others, , Nov 2016, In: British Journal of Haematology. 175, 3, p. 410-418 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The association between candidate migraine susceptibility loci and severe migraine phenotype in a clinical sample
Esserlind, A., Christensen, A. F., Steinberg, S., Grarup, N., Pedersen, Oluf Borbye, Hansen, Torben, Werge, Thomas, Hansen, T. F., Husemoen, L. L. N., Linneberg, Allan René, Budtz-Joergensen, Esben, Westergaard, M. L., Stefansson, H. & Olesen, Jes, 2016, In: Cephalalgia : an international journal of headache. 36, 7, p. 1-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulin Resistance is Accompanied by Increased Fasting Glucagon and Delayed Glucagon Suppression in Individuals With Normal and Impaired Glucose Regulation
Faerch, K., Vistisen, D., Pacini, G., Torekov, Signe Sørensen, Johansen, N. B., Witte, D. R., Jonsson, Anna Elisabet, Pedersen, Oluf Borbye, Hansen, Torben, Lauritzen, T., Jørgensen, M. E., Ahrén, B. & Holst, Jens Juul, 8 Aug 2016, In: Diabetes. 65, 11, p. 3473-3481 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index
Felix, J. F., Bradfield, J. P., Monnereau, C., van der Valk, R. J. P., Stergiakouli, E., Chesi, A., Gaillard, R., Feenstra, B., Thiering, E., Kreiner-Møller, E., Mahajan, A., Pitkänen, N., Joro, R., Cavadino, A., Huikari, V., Franks, S., Groen-Blokhuis, M. M., Cousminer, D. L., Marsh, J. A., Lehtimäki, T. & 31 others, , 2016, In: Human Molecular Genetics. 25, 2, p. 389-403Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulation of autophagy in human skeletal muscle: effects of exercise, exercise training and insulin stimulation
Fritzen, Andreas Mæchel, Madsen, A. L. B., Kleinert, Maximilian, Treebak, Jonas Thue, Lundsgaard, Anne-Marie, Jensen, Thomas Elbenhardt, Richter, Erik A., Wojtaszewski, Jørgen F P, Kiens, Bente & Frøsig, C., 2016, In: Journal of Physiology. 594, 3, p. 745-761 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Normal values of left ventricularmass and cardiac chamber volumes assessed by 320-detector computed tomography angiography in the Copenhagen General Population Study
Fuchs, A., Mejdahl, M. R., Kühl, J. T., Stisen, Z. R., Nilsson, E. J. P., Køber, Lars Valeur, Nordestgaard, Børge & Kofoed, Klaus Fuglsang, 2016, In: European Heart Journal Cardiovascular Imaging. 17, 9, p. 1009-1017 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The genetic architecture of type 2 diabetes
Fuchsberger, C., Flannick, J., Teslovich, T. M., Mahajan, A., Agarwala, V., Gaulton, K. J., Ma, C., Fontanillas, P., Moutsianas, L., McCarthy, D. J., Rivas, M. A., Perry, J. R. B., Sim, X., Blackwell, T. W., Robertson, N. R., Rayner, N. W., Cingolani, P., Locke, A. E., Fernandez Tajes, J., Highland, H. M. & 281 others, , 4 Aug 2016, In: Nature. 536, 7614, p. 41-47 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evaluation of type 2 diabetes genetic risk variants in Chinese adults: findings from 93,000 individuals from the China Kadoorie Biobank
Gan, W., Walters, R. G., Holmes, M. V., Bragg, F., Millwood, I. Y., Banasik, Karina, Chen, Y., Du, H., Iona, A., Mahajan, A., Yang, L., Bian, Z., Guo, Y., Clarke, R. J., Li, L., McCarthy, M. I., Chen, Z. & China Kadoorie Biobank Collaborative Group, C. K. B. C. G., 2016, In: Diabetologia. 59, 7, p. 1446-1457 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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The isoenzyme pattern of LDH does not play a physiological role; except perhaps during fast transitions in energy metabolism
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Determinants of plasma levels of proglucagon and the metabolic impact of glucagon receptor signalling: a UK Biobank study
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The interplay between birth weight and obesity in determining childhood and adolescent cardiometabolic risk
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Targeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment
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