- 2015
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Directional dominance on stature and cognition in diverse human populations
Joshi, P. K., Esko, T., Mattsson, H., Eklund, N., Gandin, I., Nutile, T., Jackson, A. U., Schurmann, C., Smith, A. V., Zhang, W., Okada, Y., Stančáková, A., Faul, J. D., Zhao, W., Bartz, T. M., Concas, M. P., Franceschini, N., Enroth, S., Vitart, V., Trompet, S. & 31 others, , 23 Jul 2015, In: Nature. 523, p. 459-62 4 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Influence of gastrointestinal factors on glucose metabolism in patients with cirrhosis
Junker, A. E., Gluud, Lise Lotte, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, Oct 2015, In: Journal of Gastroenterology and Hepatology. 30, 10, p. 1522-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interactions of Lipid Genetic Risk Scores with Estimates of Metabolic Health in a Danish Population
Justesen, Johanne Marie, Allin, K. H., Sandholt, C. H., Borglykke, A., Krarup, N. T., Grarup, N., Linneberg, Allan René, Jørgensen, T., Hansen, Torben & Pedersen, Oluf Borbye, 24 Feb 2015, In: Circulation. Cardiovascular genetics. 8, p. 465-72 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Clearance of glucoregulatory peptide hormones during haemodialysis and haemodiafiltration in non-diabetic end-stage renal disease patients
Jørgensen, M. B., Idorn, T., Knop, Filip Krag, Holst, Jens Juul, Hornum, Mads & Feldt-Rasmussen, Bo, Mar 2015, In: Nephrology, Dialysis, Transplantation. 30, 3, p. 513-20 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Improvements in glucose metabolism early after gastric bypass surgery are not explained by increases in total bile acids and fibroblast growth factor 19 concentrations
Jørgensen, N. B., Dirksen, C., Bojsen-Møller, K. N., Kristiansen, V. B., Wulff, B. S., Rainteau, D., Humbert, L., Rehfeld, Jens Frederik, Holst, Jens Juul, Madsbad, Sten & Clausen, T. R., Mar 2015, In: The Journal of clinical endocrinology and metabolism. 100, 3, p. E396-406 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation
Kato, N., Loh, M., Takeuchi, F., Verweij, N., Wang, X., Zhang, W., Kelly, T. N., Saleheen, D., Lehne, B., Mateo Leach, I., Drong, A. W., Abbott, J., Wahl, S., Tan, S-T., Scott, W. R., Campanella, G., Chadeau-Hyam, M., Afzal, U., Ahluwalia, T. V. S., Bonder, M. J. & 31 others, , 2015, In: Nature Genetics. 47, 11, p. 1282-93 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Gastric emptying and disease activity in inflammatory bowel disease
Keller, J., Binnewies, U., Rösch, M., Holst, Jens Juul, Beglinger, C., Andresen, V. & Layer, P., 2015, In: European Journal of Clinical Investigation. 45, 12, p. 1234-42 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Incretin and glucagon levels in adult offspring exposed to maternal diabetes in pregnancy
Kelstrup, L., Clausen, Tine Dalsgaard, Mathiesen, Elisabeth, Hansen, Torben, Holst, Jens Juul & Damm, Peter, 2015, In: Journal of Clinical Endocrinology and Metabolism. 100, 5, p. 1967-75 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Maternal prepregnancy waist circumference and BMI in relation to gestational weight gain and breastfeeding behavior: the CARDIA study
Kirkegaard, H., Nohr, E. A., Rasmussen, K. M., Stovring, H., Sørensen, Thorkild I.A., Lewis, C. E. & Gunderson, E. P., Aug 2015, In: The American Journal of Clinical Nutrition. 102, 2, p. 393-401 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Maternal weight change from prepregnancy to 7 years postpartum: the influence of behavioral factors
Kirkegaard, H., Stovring, H., Rasmussen, K. M., Abrams, B., Sørensen, Thorkild I.A. & Nohr, E. A., Apr 2015, In: Obesity. 23, 4, p. 870-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Prior AICAR stimulation increases insulin sensitivity in mouse skeletal muscle in an AMPK-dependent manner
Kjøbsted, Rasmus, Treebak, Jonas Thue, Fentz, J., Lantier, L., Viollet, B., Birk, Jesper Bratz, Schjerling, Peter, Björnholm, M., Zierath, Juleen R & Wojtaszewski, Jørgen F P, 2015, In: Diabetes. 64, 6, p. 2042-2055 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sensing of triacylglycerol in the gut: different mechanisms for fatty acids and 2-monoacylglycerol
Kleberg, K., Jacobsen, A. K., Ferreira, J. G., Windeløv, Johanne Agerlin, Rehfeld, Jens Frederik, Holst, Jens Juul, de Araujo, I. E. & Hansen, Harald S., 16 Jan 2015, In: The Journal of Physiology. 593, 8, p. 2097-109 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The MicroRNA Repertoire in Enteroendocrine Cells: Identification of miR-375 as a Potential Regulator of the Enteroendocrine Lineage
Knudsen, L. A., Petersen, N., Schwartz, Thue W. & Egerod, Kristoffer Lihme, Nov 2015, In: Endocrinology. 156, 11, p. 3971-83 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of acute exercise on pancreatic endocrine function in subjects with type 2 diabetes
Knudsen, S. H., Karstoft, K., Winding, K., Holst, Jens Juul, Pedersen, Bente Klarlund & Solomon, T., Feb 2015, In: Diabetes, Obesity and Metabolism. 17, 2, p. 207-210 4 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
GENETICALLY HIGH PLASMA VITAMIN C, INTAKE OF FRUIT AND VEGETABLES, AND RISK OF ISCHEMIC HEART DISEASE AND ALL-CAUSE MORTALITY: A MENDELIAN RANDOMIZATION STUDY
Kobylecki, C., Afzal, Shoaib, Smith, G. D. & Nordestgaard, Børge, 2015, In: Atherosclerosis.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Dietary Fiber-Induced Improvement in Glucose Metabolism Is Associated with Increased Abundance of Prevotella
Kovatcheva-Datchary, P., Nilsson, A., Akrami, R., Lee, Y. S., De Vadder, F., Arora, T., Hallen, A., Martens, E., Björck, I. & Bäckhed, G. F., 1 Dec 2015, In: Cell Metabolism. 22, 6, p. 971-82 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A genetic risk score of 45 coronary artery disease risk variants associates with increased risk of myocardial infarction in 6041 Danish individuals
Krarup, N. T., Borglykke, A., Allin, K. H., Sandholt, C. H., Justesen, Johanne Marie, Andersson, E. A., Grarup, N., Jørgensen, T., Pedersen, O. & Hansen, T., Jun 2015, In: Atherosclerosis. 240, 2, p. 305-10 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Intake of macro- and micronutrients in Danish vegans
Kristensen, N. B., Madsen, M. L., Hansen, T. H., Allin, K. H., Hoppe, C., Fagt, S., Lausten, M. S., Gøbel, R. J., drb459, drb459, Hansen, Torben & Pedersen, Oluf Borbye, 30 Oct 2015, In: Nutrition Journal. 14, 1, p. 1-10 10 p., 115.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular Mechanisms of Glucose-Stimulated GLP-1 Secretion From Perfused Rat Small Intestine
Kuhre, Rune Ehrenreich, Frost, C. R., Svendsen, B. & Holst, Jens Juul, Feb 2015, In: Diabetes. 64, 2, p. 370-382 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucose stimulates neurotensin secretion from the rat small intestine by mechanisms involving SGLT1 and GLUT2 leading to cell depolarization and calcium influx
Kuhre, Rune Ehrenreich, Bechmann, L. E., Hartmann, Bolette, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 21 Apr 2015, In: American Journal of Physiology: Endocrinology and Metabolism. 308, 12, p. E1123–E1130 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Measurement of the incretin hormones: glucagon-like peptide-1 and glucose-dependent insulinotropic peptide
Kuhre, Rune Ehrenreich, Albrechtsen, Nicolai Jacob Wewer, Hartmann, Bolette, Deacon, Carolyn F. & Holst, Jens Juul, Apr 2015, In: Journal of Diabetes and its Complications. 29, 3, p. 445-450 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Signal Transduction Inhibitors as Promising Anticancer Agents
Kumar, R., Dos Santos, C., Ahluwalia, Tarun Veer Singh & Singh, S., 2015, In: BioMed Research International. 2015, p. 1-2 2 p., 584170.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Auto-inflammatory challenge of the endolymphatic sac - Cochlear damage measured by distortion product oto-acoustic emissions
Larsen, M., Friis, M., Rift, Charlotte Vestrup, Poulsen, Steen Seier, Lund, S. P. & Qvortrup, Klaus, 2015, In: Acta Oto-Laryngologica. 135, 8, p. 758-764 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reference values for serum total adiponectin in healthy non-obese children and adolescents
Lausten-Thomsen, U., Christiansen, M., Fonvig, C. E., Trier, C., Pedersen, Oluf Borbye, Hansen, Torben & Holm, Jens-Christian, 23 Oct 2015, In: Clinica Chimica Acta. 450, p. 11-4 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effects of TNF-α on GLP-1-stimulated plasma glucose kinetics
Lehrskov-Schmidt, L., Lehrskov-Schmidt, L., Nielsen, S. T., Holst, Jens Juul, Møller, K. & Solomon, T. P. J., Apr 2015, In: The Journal of clinical endocrinology and metabolism. 100, 4, p. E616-E622 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exercise-based cardiac rehabilitation in patients with heart failure: a meta-analysis of randomised controlled trials between 1999 and 2013
Lewinter, C., Doherty, P., Gale, C. P., Crouch, S., Stirk, L., Lewin, R. J., LeWinter, M. M., Ades, P. A., Køber, Lars Valeur & Bland, J. M., Dec 2015, In: European Journal of Preventive Cardiology. 22, 12, p. 1504-1512 9 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Whole exome sequencing identifies frequent somatic mutations in cell-cell adhesion genes in chinese patients with lung squamous cell carcinoma
Li, C., Gao, Z., Li, F., Li, X., Sun, Y., Wang, M., Li, D., Wang, R., Li, F., Fang, R., Pan, Y., Luo, X., He, J., Zheng, L., Xia, J., Qiu, L., He, J., Ye, T., Zhang, R., He, M. & 32 others, , 2015, In: Scientific Reports. 5, 11 p., 14237 .Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of PKCδ in Insulin Sensitivity and Skeletal Muscle Metabolism
Li, M., Vienberg, S. G., Bezy, O., O'Neill, B. T. & Kahn, C. R., Dec 2015, In: Diabetes. 64, 12, p. 4023-32 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Macro fat and micro fat: insulin sensitivity and gender dependent response of adipose tissue to isocaloric diet change
Li, Y., Gaillard, J. R., McLaughlin, T., Sørensen, Thorkild I.A. & Periwal, V., 10 Oct 2015, In: Adipocytes. 4, 4, p. 256-63 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incretin effect after oral amino Acid ingestion in humans
Lindgren, O., Pacini, G., Tura, A., Holst, Jens Juul, Deacon, Carolyn F. & Ahrén, B., Mar 2015, In: The Journal of clinical endocrinology and metabolism. 100, 3, p. 1172-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of Smoking on Blood Pressure and Resting Heart Rate: A Mendelian Randomisation Meta-Analysis in the CARTA Consortium
Linneberg, A., Jacobsen, R. K., Skaaby, T., Taylor, A. E., Fluharty, M. E., Jeppesen, J. L., Bjørngaard, J. H., Åsvold, B. O., Gabrielsen, M. E., Campbell, A., Marioni, R. E., Kumari, M., Marques-Vidal, P., Kaakinen, M., Cavadino, A., Postmus, I., Ahluwalia, T. V. S., Wannamethee, S. G., Lahti, J., Räikkönen, K. & 40 others, , 2015, In: Circulation: Cardiovascular Genetics. 8, p. 832-841 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic studies of body mass index yield new insights for obesity biology
Locke, A. E., Kahali, B., Berndt, S. I., Justice, A. E., Pers, T. H., Day, F. R., Powell, C., Vedantam, S., Buchkovich, M. L., Yang, J., Croteau-Chonka, D. C., Esko, T., Fall, T., Ferreira, T., Gustafsson, S., Kutalik, Z., Luan, J., Mägi, R., Randall, J. C., Winkler, T. W. & 31 others, , 12 Feb 2015, In: Nature. 518, 7538, p. 197-206 24 p., 14177.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Browning of human adipocytes requires KLF11 and reprogramming of PPARγ superenhancers
Loft, A., Forss, I., Siersbæk, M. S., Schmidt, S. F., Larsen, A. B., Madsen, J. G. S., Pisani, D. F., Nielsen, R., Aagaard, M. M., Mathison, A., Neville, M. J., Urrutia, R., Karpe, F., Amri, E. & Mandrup, S., 2015, In: Genes & Development. 29, p. 7-22 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preoperative β-cell function in patients with type 2 diabetes is important for the outcome of Roux-en-Y gastric bypass surgery
Lund, M. T., Hansen, M., Skaaby, Stinna, Dalby, S., Støckel, M., Floyd, A. K., Bech, K., Helge, Jørn Wulff, Holst, Jens Juul & Dela, Flemming, 13 Apr 2015, In: The Journal of Physiology. 593, 14, p. 3123-33 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Histone deacetylase 3 inhibition improves glycaemia and insulin secretion in obese diabetic rats
Lundh, M., Galbo, T., Poulsen, Steen Seier & Mandrup-Poulsen, Thomas, Jul 2015, In: Diabetes, Obesity and Metabolism. 17, 7, p. 703-7 5 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Asthma in patients with psoriasis
Lønnberg, A. S., Skov, L., Skytthe, A., Kyvik, K. O., Pedersen, Oluf Borbye, Meteran, Howraman, Backer, Vibeke & Thomsen, Simon Francis, 2015, In: British Journal of Dermatology. p. 1660-1661Research output: Contribution to journal › Letter › Research › peer-review
- Published
Biotin starvation causes mitochondrial protein hyperacetylation and partial rescue by the SIRT3-like deacetylase Hst4p
Madsen, C. T., Sylvestersen, K. B., Young, C., Buch-Larsen, Sara Charlotte, Poulsen, J. W., Andersen, M. A., Palmqvist, E. A., Hey-Mogensen, M., Jensen, P. B., Treebak, Jonas Thue, Lisby, Michael & Nielsen, Michael Lund, 2015, In: Nature Communications. 6, 12 p., 7726.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
iRNA-seq: computational method for genome-wide assessment of acute transcriptional regulation from total RNA-seq data
Madsen, J. G. S., Schmidt, S. F., Larsen, B. D., Loft, A., Nielsen, R. & Mandrup, S., 31 Mar 2015, In: Nucleic Acids Research. 43, 6, p. 1-9 9 p., e40.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification and Functional Characterization of G6PC2 Coding Variants Influencing Glycemic Traits Define an Effector Transcript at the G6PC2-ABCB11 Locus
Mahajan, A., Sim, X., Ng, H. J., Manning, A., Rivas, M. A., Highland, H. M., Locke, A. E., Grarup, N., Im, H. K., Cingolani, P., Flannick, J., Fontanillas, P., Fuchsberger, C., Gaulton, K. J., Teslovich, T. M., Rayner, N. W., Robertson, N. R., Beer, N. L., Rundle, J. K., Bork-Jensen, J. & 31 others, , Jan 2015, In: P L o S Genetics. 11, 1, p. 1-25 25 p., e1004876.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The 2-monoacylglycerol moiety of dietary fat appears to be responsible for the fat-induced release of GLP-1 in humans.
Mandøe, M. J., Hansen, K. B., Hartmann, Bolette, Rehfeld, Jens Frederik, Holst, Jens Juul & Hansen, Harald S., 2015, In: The American Journal of Clinical Nutrition. 102, 3, p. 548-555 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Downregulation of 5-HT7 Serotonin Receptors by the Atypical Antipsychotics Clozapine and Olanzapine. Role of Motifs in the C-Terminal Domain and Interaction with GASP-1
Manfra, O., Van Craenenbroeck, K., Skieterska, K., Frimurer, Thomas Michael, Schwartz, Thue W., Levy, F. O. & Andressen, K. W., Jul 2015, In: A C S Chemical Neuroscience. 6, 7, p. 1206–1218 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
RNA-Seq and Mass-Spectrometry-Based Lipidomics Reveal Extensive Changes of Glycerolipid Pathways in Brown Adipose Tissue in Response to Cold
Marcher, A., Loft, A., Nielsen, R., Vihervaara, T., Madsen, J. G. S., Sysi-Aho, M., Ekroos, K. & Mandrup, S., 1 Dec 2015, In: Cell Reports. 13, 9, p. 2000-13 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The gut microbiota modulates host amino acid and glutathione metabolism in mice
Mardinoglu, A., Shoaie, S., Bergentall, M., Ghaffari, P., Zhang, C., Larsson, E., Bäckhed, G. F. & Nielsen, J., 2015, In: Molecular Systems Biology. 11, 10, p. 1-15 15 p., 834.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of moderate- and high-intensity acute exercise on appetite in obese individuals
Martins, C., Stensvold, D., Finlayson, G., Holst, Jens Juul, Wisloff, U., Kulseng, B., Morgan, L. & King, N. A., Jan 2015, In: Medicine and Science in Sports and Exercise. 47, 1, p. 40-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Immediate enhancement of first-phase insulin secretion and unchanged glucose effectiveness in patients with type 2 diabetes after Roux-en-Y gastric bypass
Martinussen, C., Bojsen-Moller, K. N., Dirksen, C., Jacobsen, S. H., Jørgensen, N. B., Kristiansen, V. B., Holst, Jens Juul & Madsbad, Sten, 15 Mar 2015, In: American Journal of Physiology: Endocrinology and Metabolism. 308, 6, p. E535-44 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Central serotonergic neurons activate and recruit thermogenic brown and beige fat and regulate glucose and lipid homeostasis
McGlashon, J. M., Gorecki, M. C., Kozlowski, A. E., Thirnbeck, C. K., Markan, K. R., Leslie, K. L., Kotas, M. E., Potthoff, M. J., Richerson, G. B. & Gillum, M. P., May 2015, In: Cell Metabolism. 21, 5, p. 692-705 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of Antibiotics on Gut Microbiota, Gut Hormones and Glucose Metabolism
Mikkelsen, K. H., Frost, M., Bahl, M. I., Licht, T. R., Jensen, U. S., Rosenberg, Jacob, Pedersen, Oluf Borbye, Hansen, Torben, Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, 12 Nov 2015, In: PLOS ONE. 10, 11, p. 1-14 e0142352.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Use of Antibiotics and Risk of Type 2 Diabetes: A Population-Based Case-Control Study
Mikkelsen, K. H., Knop, Filip Krag, Frost, M., Hallas, J. & Pottegård, A., 2015, In: Journal of Clinical Endocrinology and Metabolism. 100, 10, p. 3633-40 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Uncovering the genetic history of the present-day greenlandic population
Moltke, Ida, Fumagalli, M., Korneliussen, Thorfinn Sand, Crawford, J. E., Bjerregaard, P., Jørgensen, M. E., Grarup, N., Gulløv, H. C., Linneberg, Allan René, Pedersen, Oluf Borbye, Hansen, Torben, Nielsen, Rasmus & Albrechtsen, Anders, 2015, In: American Journal of Human Genetics. 96, 1, p. 54-69 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prenatal exposure to systemic antibacterials and overweight and obesity in Danish schoolchildren: a prevalence study
Mor, A., Antonsen, S., Kahlert, J., Holsteen, V., Jørgensen, S., Holm-Pedersen, J., Sørensen, H. T., Pedersen, Oluf Borbye & Ehrenstein, V., 2015, In: International journal of obesity (2005). 39, 10, p. 1450-1455 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Heavier smoking may lead to a relative increase in waist circumference: evidence for a causal relationship from a Mendelian randomisation meta-analysis. The CARTA consortium
Morris, R. W., Taylor, A. E., Fluharty, M. E., Bjørngaard, J. H., Åsvold, B. O., Elvestad Gabrielsen, M., Campbell, A., Marioni, R., Kumari, M., Korhonen, T., Männistö, S., Marques-Vidal, P., Kaakinen, M., Cavadino, A., Postmus, I., Husemoen, L. L. N., Skaaby, T., Ahluwalia, T. V. S., Treur, J. L., Willemsen, G. & 42 others, , 2015, In: B M J Open. 5, 8, p. 1-10 10 p., e008808.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Novel combinatorial therapies involving leptin: Opportunities for mechanistic advances and therapeutic translation in human diseases
Müller, T. D., Clemmensen, Christoffer, Finan, B., Dimarchi, R. D. & Tschöp, M. H., 1 Jan 2015, Leptin: Regulation and Clinical Applications. Springer, p. 267-279 13 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Association study between CDH2 and Gilles de la Tourette syndrome in a Danish cohort
Nazaryan, L., Bertelsen, B., Padmanabhuni, S. S., Debes, N. M., LuCamp, L., Have, C. T. & Tümer, Asuman Zeynep, 30 Aug 2015, In: Psychiatry Research. 228, 3, p. 974-5 2 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Contribution of common non-synonymous variants in PCSK1 to body-mass index variation and risk of obesity: a systematic review and meta-analysis with evidence from up to 331,175 individuals
Nead, K. T., Li, A., Wehner, M. R., Neupane, B., Gustafsson, S., Butterworth, A., Engert, J. C., Davis, A. D., Hegele, R. A., Miller, R., den Hoed, M., Khaw, K-T., Oskari Kilpeläinen, T., Wareham, N., Edwards, T. L., Hallmans, G., Varga, T. V., Kardia, S. L. R., Smith, J. A., Zhao, W. & 31 others, , 17 Mar 2015, In: Human Molecular Genetics. 24, 2, p. 3582–3594 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Early child care and obesity at 12 months of age in the Danish National Birth Cohort
Neelon, S. E. B., Andersen, C. S., Morgen, C. S., Kamper-Jørgensen, Mads, Oken, E., Gillman, M. W. & Sørensen, Thorkild I.A., 2015, In: International journal of obesity (2005). 39, p. 33-38 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
NKG2D-Dependent Activation of Dendritic Epidermal T cells in Contact Hypersensitivity
Nielsen, M. M., Dyring-Andersen, Beatrice, Schmidt, J. D., Witherden, D., Lovato, P., Woetmann, Anders , Ødum, Niels, Poulsen, Steen Seier, Havran, W. L., Geisler, Carsten & Bonefeld, Charlotte Menne, May 2015, In: Journal of Investigative Dermatology. 135, 5, p. 1311-19 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulin resistance as a physiological defense against metabolic stress: implications for the management of subsets of type 2 diabetes
Nolan, C. J., Ruderman, N. B., Kahn, S. E., Pedersen, Oluf Borbye & Prentki, M., Mar 2015, In: Diabetes. 64, 3, p. 673-86 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Response to Comments on Nolan et al. Insulin Resistance as a Physiological Defense Against Metabolic Stress: Implications for the Management of Subsets of Type 2 Diabetes. Diabetes 2015;64:673-686
Nolan, C. J., Ruderman, N. B., Kahn, S. E., Pedersen, Oluf Borbye & Prentki, M., 2015, In: Diabetes. 64, 10, p. e38-9 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Mutation-Guided Unbiased Modeling of the Fat Sensor GPR119 for High-Yield Agonist Screening.
Norn, C., Pedersen, M. H., Engelstoft, M. S., Kim, S. H., Lehmann, J., Jones, R. M., Schwartz, Thue W. & Frimurer, Thomas Michael, 2015, In: Structure. 23, 12, p. 2377-2386 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expression of the short chain fatty acid receptor GPR41/FFAR3 in autonomic and somatic sensory ganglia
Nøhr, M. K., Egerod, Kristoffer Lihme, Christiansen, S. H., Gille, A., Offermanns, S., Schwartz, Thue W. & Møller, Morten, 2 Apr 2015, In: Neuroscience. 290, p. 126-37 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diabetes mellitus and metabolic syndrome
Ortega, E., Martín-Cordero, L., Garcia-Roves, P. M., Chicco, A. J., Gonzalez-Franquesa, A. & Marado, D., 1 Jan 2015, Biomarkers of Cardiometabolic Risk, Inflammation and Disease. Springer, p. 55-79 25 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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HOODS: finding context-specific neighborhoods of proteins, chemicals and diseases
Palleja, A. & Jensen, Lars Juhl, 2015, In: PeerJ. 3, p. 1-10 10 p., e1057.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparative analyses of QTLs influencing obesity and metabolic phenotypes in pigs and humans
Pant, S. D., Karlskov-Mortensen, Peter, Jacobsen, M. J., Cirera, Susanna, Kogelman, L., Bruun, Camilla Vibeke Sichlau, Mark, T., Jørgensen, Claus Bøttcher, Grarup, N., Appel, E. V. R., Galjatovic, E. A. A., Hansen, T., Pedersen, Oluf Borbye, Guerin, M., Huby, T., Lesnik, P., Meuwissen, T. H. E., Kadarmideen, H. & Fredholm, Merete, 8 Sep 2015, In: PLOS ONE. 10, 9, 22 p., e0137356.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis
Paternoster, L., Standl, M., Waage, J., Baurecht, H., Hotze, M., Strachan, D. P., Curtin, J. A., Bønnelykke, K., Tian, C., Takahashi, A., Esparza-Gordillo, J., Alves, A. C., Thyssen, J. P., den Dekker, H. T., Ferreira, M. A., Altmaier, E., Sleiman, P. M. A., Xiao, F. L., Gonzalez, J. R., Marenholz, I. & 31 others, , Dec 2015, In: Nature Genetics. 47, 12, p. 1449-56 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GPR40 (FFAR1) – Combined Gs and Gq signaling in vitro is associated with robust incretin secretagogue action ex vivo and in vivo
Pedersen, M. H., Bentsen, M. A., Husted, Anna Sofie, Ekberg, J. P., Wright, M. J., Di Salvo, J., Weinglass, A. B., Engelstoft, M. S., Madsen, A. N., Lückmann, Michael, Miller, M. W., Trujillo, M. E., Frimurer, Thomas Michael, Holst, Birgitte, Howard, A. D. & Schwartz, Thue W., Jan 2015, In: Molecular Metabolism. 4, 1, p. 3-14 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma proteomics classifiers improve risk prediction for renal disease in patients with hypertension or type 2 diabetes
Pena, M. J., Jankowski, J., Heinze, G., Kohl, M., Heinzel, A., Bakker, S. J. L., Gansevoort, R. T., Rossing, Peter, de Zeeuw, D., Heerspink, H. J. L. & Jankowski, V., Oct 2015, In: Journal of Hypertension. 33, 10, p. 2123-32 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prognostic clinical and molecular biomarkers of renal disease in type 2 diabetes
Pena, M. J., de Zeeuw, D., Mischak, H., Jankowski, J., Oberbauer, R., Woloszczuk, W., Benner, J., Dallmann, G., Mayer, B., Mayer, G., Rossing, Peter & Lambers Heerspink, H. J., Aug 2015, In: Nephrology, Dialysis, Transplantation. 30, Suppl 4, p. iv86-95Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hepatic NAD salvage pathway is enhanced in mice on a high-fat diet
Penke, M., Larsen, P. S., Schuster, S., Dall, M., Jensen, Benjamin Anderschou Holbech, Gorski, T., Meusel, A., Richter, S., Vienberg, S. G., Treebak, Jonas Thue, Kiess, W. & Garten, A., 2015, In: Molecular and Cellular Endocrinology. 412, p. 65-72 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cuff inflations do not affect night-time blood pressure: comparison of 24 h ambulatory blood pressure measured by a cuff and a tonometric device in type 2 diabetes
Petersen, E. H., Theilade, S., Hansen, T. W., Lindhardt, M. K. & Rossing, Peter, Dec 2015, In: Blood Pressure Monitoring. 20, 6, p. 369-72 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Severe hypoglycaemia during treatment with sulphonylureas in patients with type 2 diabetes in the Capital Region of Denmark
Pilemann-Lyberg, S., Thorsteinsson, B., Snorgaard, O., Zander, M., drb459, drb459 & Røder, M. E., 2015, In: Diabetes Research and Clinical Practice. 110, 2, p. 202-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inflammatory and metabolic alterations of Kager's fat pad in chronic achilles tendinopathy
Pingel, Jessica, Petersen, M. C. H., Fredberg, U., Kjær, S. G., Quistorff, B., Langberg, Henning & Hansen, Jacob B., 2015, In: P L o S One. 10, 5, 13 p., e0127811.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of efferent cholinergic transmission for the insulinotropic and glucagonostatic effects of GLP-1
Plamboeck, A., Veedfald, Simon, Deacon, Carolyn F., Hartmann, Bolette, Vilsbøll, T., Knop, Filip Krag & Holst, Jens Juul, Sep 2015, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 309, 5, p. R544-51 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DISEASES: Text mining and data integration of disease-gene associations
Pletscher-Frankild, S., Pallejà, A., Tsafou, K., Binder, J. X. & Jensen, Lars Juhl, Mar 2015, In: Methods. 74, p. 83-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Circulating miR-192 and miR-193b are markers of prediabetes and are modulated by an exercise intervention
Párrizas, M., Brugnara, L., Esteban, Y., González-Franquesa, A., Canivell, S., Murillo, S., Gordillo-Bastidas, E., Cussó, R., Cadefau, J. A., García-Roves, P. M., Servitja, J. & Novials, A., Mar 2015, In: The Journal of clinical endocrinology and metabolism. 100, 3, p. E407-15Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dietary intake, FTO genetic variants and adiposity: a combined analysis of over 16,000 children and adolescents
Qi, Q., Downer, M. K., Oskari Kilpeläinen, T., Taal, H. R., Barton, S. J., Ntalla, I., Standl, M., Boraska, V., Huikari, V., Kiefte-de Jong, J. C., Körner, A., Lakka, T. A., Liu, G., Magnusson, J., Okuda, M., Raitakari, O., Richmond, R., Scott, R. A., Bailey, M. E. S., Scheuermann, K. & 22 others, , Jul 2015, In: Diabetes. 64, 7, p. 2467-76 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impaired oxidative capacity due to decreased CPT1b levels as a contributing factor to fat accumulation in obesity
Ratner, C., Madsen, A. N., Kristensen, L. V., Skov, Louise Julie, Pedersen, K. S., Mortensen, Ole Hartvig, Knudsen, Gitte Moos, Raun, K. & Holst, Birgitte, 8 Apr 2015, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 308, 11, p. R973-R982 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dual-hormone treatment with insulin and glucagon in patients with type 1 diabetes
Reiband, H. K., Schmidt, S., Ranjan, A., Holst, Jens Juul, Madsbad, Sten & Nørgaard, Kirsten, 2015, In: Diabetes - Metabolism: Research and Reviews (Print Edition). 31, 7, p. 672-9 8 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Effect of Roux-en-Y gastric bypass on the distribution and hormone expression of small-intestinal enteroendocrine cells in obese patients with type 2 diabetes
Rhee, N. A., Wahlgren, C. D., Pedersen, J., Mortensen, B., Langholz, E., Wandall, E. P., Friis, S. U., Vilmann, Peter, Paulsen, S. J., Kristiansen, V. B., Jelsing, J., Dalbøge, L. S., Poulsen, Steen Seier, Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, 2015, In: Diabetologia. 58, 10, p. 2254-2258 5 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Exploring possible epigenetic mediation of early-life environmental exposures on adiposity and obesity development
Richmond, R. C., Timpson, N. J. & Sørensen, Thorkild I.A., Aug 2015, In: International Journal of Epidemiology. 44, 4, p. 1191-8 8 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Population genetic differentiation of height and body mass index across Europe
Robinson, M. R., Hemani, G., Medina-Gomez, C., Mezzavilla, M., Esko, T., Shakhbazov, K., Powell, J. E., Vinkhuyzen, A., Berndt, S. I., Gustafsson, S., Justice, A. E., Kahali, B., Locke, A. E., Pers, T. H., Vedantam, S., Wood, A. R., van Rheenen, W., Andreassen, O. A., Gasparini, P., Metspalu, A. & 23 others, , Nov 2015, In: Nature Genetics. 47, 11, p. 1357-62, 2 unpag. Methods 8 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Peptidomics combined with cDNA library unravel the diversity of centipede venom
Rong, M., Yang, S., Wen, B., Mo, G., Kang, D., Liu, J., Lin, Z., Jiang, W., Li, B., Du, C., Yang, S., Jiang, H., Feng, Q., Xu, X., Wang, J. & Lai, R., 30 Jan 2015, In: Journal of Proteomics. 114, 1, p. 28-37 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inability to match energy intake with energy expenditure at sustained near-maximal rates of energy expenditure in older men during a 14-d cycling expedition
Rosenkilde Larsen, M., Morville, T., Riis Andersen, P., Kjær, K., Rasmusen, H., Holst, Jens Juul, Dela, Flemming, Westerterp, K., Sjödin, Anders Mikael & Helge, Jørn Wulff, 2015, In: American Journal of Clinical Nutrition. 102, 6, p. 1398-1405 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Specific inhibition of bile acid transport alters plasma lipids and GLP-1
Rudling, M., Camilleri, M., Graffner, H., Holst, Jens Juul & Rikner, L., 2015, In: B M C Cardiovascular Disorders. 15, p. 1-8 8 p., 75.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of age, BMI and HbA1c levels on the genome-wide DNA methylation and mRNA expression patterns in human adipose tissue and identification of epigenetic biomarkers in blood
Rönn, T., Volkov, P., Gillberg, L., Kokosar, M., Perfilyev, A., Jacobsen, A. L., Jørgensen, S. W., Brøns, C., Jansson, P., Eriksson, K., Pedersen, Oluf Borbye, Hansen, Torben, Groop, L., Stener-Victorin, E., Vaag, Allan, Nilsson, E. & Ling, C., 1 Jul 2015, In: Human Molecular Genetics. 24, 13, p. 3792-813 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
L-glutamine and whole protein restore first-phase insulin response and increase glucagon-like Peptide-1 in type 2 diabetes patients
Samocha-Bonet, D., Chisholm, D. J., Holst, Jens Juul & Greenfield, J. R., 2015, In: Nutrients. 7, 4, p. 2101-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association studies of human adiposity: Zooming in on synapses.
Sandholt, C. H., Grarup, N., Pedersen, Oluf Borbye & Hansen, Torben, 2015, In: Molecular and Cellular Endocrinology. 418, Part 2, p. 90-100 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Obesity Beige adipocytes-will they beat obesity?.
Sandholt, C. H. & Pedersen, Oluf Borbye, 2015, In: Nature Reviews Endocrinology. 11, 12, p. 694-696 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
About this book
Sandøe, Peter, Jensen, Karsten Klint & Whiteley, Louise, Sep 2015, RCR – A Danish textbook for courses in Responsible Conduct of Research. Jensen, K. K., Whiteley, L. & Sandøe, P. (eds.). 1. ed. Frederiksberg: Department of Food and Resource Economics, University of Copenhagen, p. 1-4 4 p.Research output: Chapter in Book/Report/Conference proceeding › Preface/postscript › Education
- Published
Optimisation of in silico derived 2-aminobenzimidazole hits as unprecedented selective kappa opioid receptor agonists
Sasmal, P. K., Krishna, C. V., Sudheerkumar Adabala, S., Rawoof, K. A., Thadi, A., Sukumar, K. P., Cheera, S., Abbineni, C., Rao, K. V. L. N., Prasanthi, A., Nijhawan, K., Jaleel, M., Ramachandran Iyer, L., Chaitanya, T. K., Tiwari, N. K., Krishna, N. L., Potluri, V., Khanna, I., Frimurer, T. M., Lückmann, M. & 3 others, , 15 Feb 2015, In: Bioorganic & Medicinal Chemistry Letters. 25, 4, p. 887-92 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Smoking and diabetes risk: building a causal case with clinical implications
Sattar, N., Sørensen, Thorkild I.A., Taylor, A. E., Morris, R. & Munafò, M. R., Dec 2015, In: The Lancet Diabetes & Endocrinology. 3, 12, p. 918-20 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No association of maternal gestational weight gain with offspring blood pressure and hypertension at age 18 years in male sibling-pairs: a prospective register-based cohort study
Scheers Andersson, E., Tynelius, P., Nohr, E. A., Sørensen, Thorkild I.A. & Rasmussen, F., 20 Mar 2015, In: PLOS ONE. 10, 3, p. 1-12 12 p., e0121202.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The renal protective effect of angiotensin receptor blockers depends on intra-individual response variation in multiple risk markers
Schievink, B., de Zeeuw, D., Parving, H., Rossing, Peter & Lambers Heerspink, H. J., Oct 2015, In: British Journal of Clinical Pharmacology. 80, 4, p. 678-86 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acute TNF-induced repression of cell identity genes is mediated by NFκB-directed redistribution of cofactors from super-enhancers
Schmidt, S. F., Larsen, B. D., Loft, A., Nielsen, R., Madsen, J. G. S. & Mandrup, S., Sep 2015, In: Genome Research. 25, 9, p. 1281-94 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of sitagliptin on counterregulatory and incretin hormones during acute hypoglycaemia in patients with type 1 diabetes: a randomized double blind placebo-controlled cross-over study
Schopman, J. E., Hoekstra, J. B. L., Frier, B. M., Ackermans, M. T., de Sonnaville, J. J. J., Stades, A. M., Zwertbroek, R., Hartmann, Bolette, Holst, Jens Juul, Knop, Filip Krag & Holleman, F., Jun 2015, In: Diabetes, Obesity and Metabolism. 17, 6, p. 546-53 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Vitamin D-rich marine Inuit diet and markers of inflammation – a population-based survey in Greenland
Schæbel, L. K., Bonefeld-Jørgensen, E. C., Laurberg, P., drb459, drb459 & Andersen, S., Oct 2015, In: Journal of Nutritional Science. 4, p. 1-8 8 p., e40.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypoglycemia-associated changes in the electroencephalogram in patients with type 1 diabetes and normal hypoglycemia awareness or unawareness
Sejling, A., Kjær, T. W., Pedersen-Bjergaard, Ulrik, Diemar, S. S., Frandsen, C. S. S., Hilsted, L., Faber, Jens, Holst, Jens Juul, Tarnow, L., Nielsen, M. N., Remvig, L. S., Thorsteinsson, B. & Juhl, C. B., May 2015, In: Diabetes. 64, 5, p. 1760-9 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Infrared thermographic assessment of changes in skin temperature during hypoglycaemia in patients with type 1 diabetes
Sejling, A., Lange, Kai, Frandsen, C. S., Diemar, S. S., Tarnow, L., Faber, Jens, Holst, Jens Juul, Hartmann, Bolette, Hilsted, Linda, Kjaer, T. W., Juhl, C. B., Thorsteinsson, B. & Pedersen-Bjergaard, Ulrik, 2015, In: Diabetologia. 58, p. 1898–1906 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Early gradual feeding with bovine colostrum improves gut function and NEC resistance relative to infant formula in preterm pigs
Shen, René Liang, Thymann, Thomas, Østergaard, M. V., Støy, A. C. F., Krych, Lukasz, Nielsen, Dennis Sandris, Lauridsen, C., Hartmann, Bolette, Holst, Jens Juul, Burrin, D. G. & Sangild, Per Torp, 2015, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 309, 5, p. G310-G323 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantifying Diet-Induced Metabolic Changes of the Human Gut Microbiome
Shoaie, S., Ghaffari, P., Kovatcheva-Datchary, P., Mardinoglu, A., Sen, P., Pujos-Guillot, E., de Wouters, T., Juste, C., Rizkalla, S., Chilloux, J., Hoyles, L., Nicholson, J. K., Dore, J., Dumas, M. E., Clement, K., Bäckhed, G. F., Nielsen, J. & MICRO-Obes Consortium, M. C., 4 Aug 2015, In: Cell Metabolism. 22, 2, p. 320-31 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The CODATwins Project: The Cohort Description of Collaborative Project of Development of Anthropometrical Measures in Twins to Study Macro-Environmental Variation in Genetic and Environmental Effects on Anthropometric Traits
Silventoinen, K., Jelenkovic, A., Sund, R., Honda, C., Aaltonen, S., Yokoyama, Y., Tarnoki, A. D., Tarnoki, D. L., Ning, F., Ji, F., Pang, Z., Ordoñana, J. R., Sánchez-Romera, J. F., Colodro-Conde, L., Burt, S. A., Klump, K. L., Medland, S. E., Montgomery, G. W., Kandler, C., McAdams, T. A. & 106 others, , Aug 2015, In: Twin Research and Human Genetics. 18, 4, p. 348-60 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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The isoenzyme pattern of LDH does not play a physiological role; except perhaps during fast transitions in energy metabolism
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