Novo Nordisk Foundation Center for Basic Metabolic Research

  1. 2015
  2. Published

    Differential effects of glucagon-like peptide-1 on microvascular recruitment and glucose metabolism in short- and long-term Insulin resistance

    Sjøberg, K. A., Rattigan, S., Jeppesen, J. F., Lundsgaard, Anne-Marie, Holst, Jens Juul & Kiens, Bente, 2015, In: Journal of Physiology. 593, 9, p. 2185-2198 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    No changes in serum tryptase after bariatric surgery

    Skaaby, T., drb459, drb459, Thomsen, S., Knudsen, A. L., Jørgensen, Niklas Rye & Linneberg, Allan René, 2015, In: Annals of Epidemiology. 25, 10, p. 800-1 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    The gut microbiota engages different signaling pathways to induce Duox2 expression in the ileum and colon epithelium

    Sommer, F. & Bäckhed, G. F., Mar 2015, In: Mucosal Immunology. 8, 2, p. 372-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Site-specific programming of the host epithelial transcriptome by the gut microbiota

    Sommer, F., Nookaew, I., Sommer, N., Fogelstrand, P. & Bäckhed, G. F., 2015, In: Genome Biology (Online Edition). 16, p. 1-15 15 p., 62.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Comment on Xu et al. Effects of Metformin on Metabolite Profiles and LDL Cholesterol in Patients With Type 2 Diabetes

    Sonne, David Peick & Knop, Filip Krag, Dec 2015, In: Diabetes Care. 38, 12, p. e215 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  7. Published

    Pancreatic Amylase and Lipase Plasma Concentrations Are Unaffected by Increments in Endogenous GLP-1 Levels Following Liquid Meal Tests

    Sonne, David Peick, Vilsbøll, T. & Knop, Filip Krag, 2015, In: Diabetes Care. 38, 5, p. e71-2 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Atmospheric Smell: hospital-based and museum-staged

    Stenslund, A., 2015, SL Grafik. 216 p.

    Research output: Book/ReportPh.D. thesis

  9. Published

    Reduced CD300LG mRNA tissue expression, increased intramyocellular lipid content and impaired glucose metabolism in healthy male carriers of Arg82Cys in CD300LG: a novel genometabolic cross-link between CD300LG and common metabolic phenotypes

    Støy, J., Kampmann, U., Mengel, A., Magnusson, N. E., Jessen, N., Grarup, N., Rungby, Jørgen, Stødkilde-Jørgensen, H., Brandslund, I., Christensen, C., Hansen, Torben, Pedersen, Oluf Borbye & Møller, N., 2015, In: BMJ open diabetes research & care. 3, 1, p. 1-12 12 p., e000095.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Updates in weight loss surgery and gastrointestinal peptides

    Svane, M. S., Bojsen-Møller, K. N., Madsbad, Sten & Holst, Jens Juul, Feb 2015, In: Current Opinion in Endocrinology, Diabetes and Obesity. 22, 1, p. 21-8 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  11. Published

    An Analysis of Cosecretion and Coexpression of Gut Hormones From Male Rat Proximal and Distal Small Intestine

    Svendsen, B., Pedersen, Jens, Albrechtsen, Nicolai Jacob Wewer, Hartmann, Bolette, Toräng, S., Rehfeld, Jens Frederik, Poulsen, Steen Seier & Holst, Jens Juul, Mar 2015, In: Endocrinology. 156, 3, p. 847-857 11 p., en20141710.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Childhood maltreatment and obesity

    Sørensen, Thorkild I.A., Aug 2015, In: Obesity. 23, 8, p. 1528 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  13. Published

    Endogenous GLP-1 mediates postprandial reductions in activation in central reward and satiety areas in patients with type 2 diabetes

    Ten Kulve, J. S., Veltman, D. J., van Bloemendaal, L., Barkhof, F., Deacon, Carolyn F., Holst, Jens Juul, Konrad, R. J., Sloan, J. H., Drent, M. L., Diamant, M. & IJzerman, R. G., Dec 2015, In: Diabetologia. 58, 12, p. 2688-98 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Associations of the Inflammatory Marker YKL-40 with Measures of Obesity and Dyslipidaemia in Individuals at High Risk of Type 2 Diabetes

    Thomsen, S. B., Gjesing, A. M. P., Rathcke, C. N., Ekstrøm, Claus Thorn, Eiberg, Hans Rudolf Lytchoff, Hansen, T., Pedersen, Oluf Borbye & drb459, drb459, 21 Jul 2015, In: PLOS ONE. 10, 7, p. 1-10 10 p., e0133672.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Assessment of body composition by dual-energy X-ray absorptiometry, bioimpedance analysis and anthropometrics in children: the Physical Activity and Nutrition in Children study

    Tompuri, T. T., Lakka, T. A., Hakulinen, M., Lindi, V., Laaksonen, D. E., Kilpeläinen, Tuomas O., Jääskeläinen, J., Lakka, H. & Laitinen, T., 2015, In: Clinical Physiology and Functional Imaging. 35, 1, p. 21-33 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    The anorexic hormone Peptide YY3-36 is rapidly metabolized to inactive Peptide YY3-34 in vivo.

    Toräng, S., Veedfald, Simon, Rosenkilde, Mette, Hartmann, Bolette & Holst, Jens Juul, 20 Jul 2015, In: Physiological Reports. 3, 7, p. 1-8 8 p., e12455.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    NNMT: A Bad Actor in Fat Makes Good in Liver

    Trammell, Sam & Brenner, C., 4 Aug 2015, In: Cell Metabolism. 22, 2, p. 200-201 2 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  18. Published

    Roux-en-Y Gastric Bypass and Vertical Banded Gastroplasty Induce Long-Term Changes on the Human Gut Microbiome Contributing to Fat Mass Regulation

    Tremaroli, V., Karlsson, F., Werling, M., Ståhlman, M., Kovatcheva-Datchary, P., Olbers, T., Fändriks, L., le Roux, C. W., Nielsen, J. & Bäckhed, G. F., 4 Aug 2015, In: Cell Metabolism. 22, 2, p. 228-38 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Biased Gs Versus Gq Proteins and β-Arrestin Signaling in the NK1 Receptor Determined by Interactions in the Water Hydrogen Bond Network

    Valentin-Hansen, L., Frimurer, Thomas Michael, Mokrosinski, J., Holliday, N. D. & Schwartz, Thue W., 2 Oct 2015, In: The Journal of Biological Chemistry. 290, 40, p. 24495-508 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Genome of the Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels

    Van Leeuwen, E. M., Karssen, L. C., Deelen, J., Isaacs, A., Medina-Gomez, C., Mbarek, H., Kanterakis, A., Trompet, S., Postmus, I., Verweij, N., Van Enckevort, D. J., Huffman, J. E., White, C. C., Feitosa, M. F., Bartz, T. M., Manichaikul, A., Joshi, P. K., Peloso, G. M., Deelen, P., Van Dijk, F. & 105 others, Willemsen, G., De Geus, E. J., Milaneschi, Y., Penninx, B. W. J. H., Francioli, L. C., Menelaou, A., Pulit, S. L., Rivadeneira, F., Hofman, A., Oostra, B. A., Franco, O. H., Leach, I. M., Beekman, M., De Craen, A. J. M., Uh, H. W., Trochet, H., Hocking, L. J., Porteous, D. J., Sattar, N., Packard, C. J., Buckley, B. M., Brody, J. A., Bis, J. C., Rotter, J. I., Mychaleckyj, J. C., Campbell, H., Duan, Q., Lange, L. A., Wilson, J. F., Hayward, C., Polasek, O., Vitart, V., Rudan, I., Wright, A. F., Rich, S. S., Psaty, B. M., Borecki, I. B., Kearney, P. M., Stott, D. J., Cupples, L. A., Jukema, J. W., Van Der Harst, P., Sijbrands, E. J., Hottenga, J. J., Uitterlinden, A. G., Swertz, M. A., Van Ommen, G. J. B., De Bakker, P. I. W., Eline Slagboom, P., Boomsma, D. I., Wijmenga, C., Van Duijn, C. M., Neerincx, P. B. T., Elbers, C. C., Palamara, P. F., Peer, I., Abdellaoui, A., Kloosterman, W. P., Van Oven, M., Vermaat, M., Li, M., Laros, J. F. J., Stoneking, M., De Knijff, P., Kayser, M., Veldink, J. H., Van Den Berg, L. H., Byelas, H., Den Dunnen, J. T., Dijkstra, M., Amin, N., Van Der Velde, K. J., Van Setten, J., Kattenberg, M., Van Schaik, B. D. C., Bot, J., Nijman, I. J., Mei, H., Koval, V., Ye, K., Lameijer, E. W., Moed, M. H., Hehir-Kwa, J. Y., Handsaker, R. E., Sunyaev, S. R., Sohail, M., Hormozdiari, F., Marschall, T., Schönhuth, A., Guryev, V., Suchiman, H. E. D., Wolffenbuttel, B. H., Platteel, M., Pitts, S. J., Potluri, S., Cox, D. R., Li, Q., Li, Y., Du, Y., Chen, R., Cao, H., Li, N., Cao, S., Wang, J. & Bovenberg, J. A., 2015, In: Nature Communications. 6, 6 p., 6065.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Pancreatic polypeptide responses to isoglycemic oral and intravenous glucose in humans with and without intact vagal innervation

    Veedfald, Simon, Plamboeck, A., Hartmann, Bolette, Svendsen, Lars Bo, Vilsbøll, T., Knop, Filip Krag & Holst, Jens Juul, Sep 2015, In: Peptides. 71, p. 229-31 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Proteome- and transcriptome-driven reconstruction of the human myocyte metabolic network and its use for identification of markers for diabetes

    Väremo, L., Schéele, Camilla Charlotte Nielsen, Broholm, C., Mardinoglu, A., Kampf, C., Asplund, A., Nookaew, I., Uhlén, M., Pedersen, Bente Klarlund & Nielsen, J., 2015, In: Cell Reports. 11, 6, p. 921-33 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

    Wessel, J., Chu, A. Y., Willems, S. M., Wang, S., Yaghootkar, H., Brody, J. A., Dauriz, M., Hivert, M-F., Raghavan, S., Lipovich, L., Hidalgo, B., Fox, K., Huffman, J. E., An, P., Lu, Y., Rasmussen-Torvik, L. J., Grarup, N., Ehm, M. G., Li, L., Baldridge, A. S. & 31 others, Stančáková, A., Abrol, R., Besse, C., Boland, A., Bork-Jensen, J., Fornage, M., Freitag, D. F., Garcia, M. E., Guo, X., Hara, K., Isaacs, A., Jakobsdottir, J., Lange, L. A., Layton, J. C., Li, M., Hua Zhao, J., Meidtner, K., Morrison, A. C., Nalls, M. A., Peters, M. J., Sabater-Lleal, M., Schurmann, C., Silveira, A., Smith, A. V., Southam, L., Allin, K. H., Jørgensen, T., Linneberg, Allan René, Hansen, Torben, Pedersen, Oluf Borbye & EPIC-InterAct Consortium, E. C., 29 Jan 2015, In: Nature Communications. 6, p. 5897

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Public Science Communication

    Whiteley, Louise, 2015, RCR – A Danish textbook for courses in Responsible Conduct of Research. Jensen, K. K., Whiteley, L. & Sandøe, P. (eds.). Frederiksberg, p. 90-107

    Research output: Chapter in Book/Report/Conference proceedingBook chapterEducation

  25. Published

    The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

    Winkler, T. W., Justice, A. E., Graff, M., Barata, L., Feitosa, M. F., Chu, S., Czajkowski, J., Esko, T., Fall, T., Kilpeläinen, T. O., Lu, Y., Mägi, R., Mihailov, E., Pers, T. H., Rüeger, S., Teumer, A., Ehret, G. B., Ferreira, T., Heard-Costa, N. L., Karjalainen, J. & 31 others, Lagou, V., Mahajan, A., Neinast, M. D., Prokopenko, I., Simino, J., Teslovich, T. M., Jansen, R., Westra, H., White, C. C., Absher, D., Ahluwalia, Tarun Veer Singh, Ahmad, S., Albrecht, E., Alves, A. C., Bragg-Gresham, J. L., de Craen, A. J. M., Bis, J. C., Bonnefond, A., Boucher, G., Banasik, Karina, Grarup, N., Hansen, Torben, Jørgensen, T., Krarup, N. T., Linneberg, Allan René, Ribel-Madsen, R., Sparsø, T. H., Melbye, M., Pedersen, Oluf Borbye, Sørensen, Thorkild I.A. & CHARGE Consortium, C. C., 1 Oct 2015, In: P L o S Genetics. 11, 10, p. 1-42 42 p., e1005378.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Synaptotagmin-7 phosphorylation mediates GLP-1-dependent potentiation of insulin secretion from β-cells

    Wu, B., Wei, S., Petersen, N., Ali, Y., Wang, X., Bacaj, T., Rorsman, P., Hong, W., Südhof, T. C. & Han, W., 11 Aug 2015, In: National Academy of Sciences. Proceedings. 112, 32, p. 9996-10001 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Linking Microbiota to Human Diseases: A Systems Biology Perspective

    Wu, H., Tremaroli, V. & Bäckhed, F., 6 Nov 2015, In: Trends in Endocrinology and Metabolism. 26, 12, p. 758-70 13 p.

    Research output: Contribution to journalReviewResearchpeer-review

  28. Published

    Tumor suppressor ASXL1 is essential for the activation of INK4B expression in response to oncogene activity and anti-proliferative signals

    Wu, X., Bekker-Jensen, I. H., Christensen, J., Rasmussen, K. D., Sidoli, S., Qi, Y., Kong, Y., Wang, X., Cui, Y., Xiao, Z., Xu, G., Williams, K., Rappsilber, J., Sønderby, C. K., Winther, Ole, Jensen, O. N. & Helin, K., 2015, In: Cell Research. 25, p. 1205-1218 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    A catalog of the mouse gut metagenome: [incl. Author Correction]

    Xiao, L., Feng, Q., Liang, S., Sonne, S. B., Xia, Z., Qiu, X., Li, X., Long, H., Zhang, J., Zhang, D., Liu, C., Fang, Z., Chou, J., Glanville, J., Hao, Q., Kotowska, D. E., Colding, C. S., Licht, T. R., Wu, D., Yu, J. & 17 others, Sung, J. J. Y., Liang, Q., Li, J., Jia, H., Lan, Z., Tremaroli, V., Dworzynski, P., Nielsen, H. B., Bäckhed, G. F., Dore, J., Le Chatelier, E., Ehrlich, S. D., Lin, J. C., Arumugam, Mani, Wang, J., Madsen, L. & Kristiansen, Karsten, 2015, In: Nature Biotechnology. 33, 10, p. 1103-1108 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Inherited coding variants at the CDKN2A locus influence susceptibility to acute lymphoblastic leukaemia in children

    Xu, H., Zhang, H., Yang, W., Yadav, R., Morrison, A. C., Qian, M., Devidas, M., Liu, Y., Perez-Andreu, V., Zhao, X., Gastier-Foster, J. M., Lupo, P. J., Neale, G., Raetz, E., Larsen, E., Bowman, W. P., Carroll, W. L., Winick, N., Williams, R., Hansen, T. & 13 others, Holm, Jens-Christian, Mardis, E., Fulton, R., Pui, C., Zhang, J., Mullighan, C. G., Evans, W. E., Hunger, S. P., Gupta, R., Schmiegelow, Kjeld, Loh, M. L., Relling, M. V. & Yang, J. J., 2015, In: Nature Communications. 6, p. 1-7 7 p., 7553.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Embryo genome profiling by single-cell sequencing for preimplantation genetic diagnosis in a β-thalassemia family

    Xu, Y., Chen, S., Yin, X., Shen, X., Pan, X., Chen, F., Jiang, H., Liang, Y., Wang, W., Xu, X., Wang, J., Zhang, X., Zhou, C. & Wang, J., 2015, In: Clinical Chemistry. 61, 4, p. 617-626 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Early phase glucagon and insulin secretory abnormalities, but not incretin secretion, are similarly responsible for hyperglycemia after ingestion of nutrients

    Yabe, D., Kuroe, A., Watanabe, K., Iwasaki, M., Hamasaki, A., Hamamoto, Y., Harada, N., Yamane, S., Lee, S., Murotani, K., Deacon, Carolyn F., Holst, Jens Juul, Hirano, T., Inagaki, N., Kurose, T. & Seino, Y., 2015, In: Journal of Diabetes and its Complications. 29, p. 413-421 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Association analysis of 29,956 individuals confirms that a low-frequency variant at CCND2 halves the risk of type 2 diabetes by enhancing insulin secretion

    Yaghootkar, H., Stancáková, A., Freathy, R. M., Vangipurapu, J., Weedon, M. N., Xie, W., Wood, A. R., Ferrannini, E., Mari, A., Ring, S. M., Lawlor, D. A., Davey Smith, G., Jørgensen, T., Hansen, T., Pedersen, O., Steinthorsdottir, V., Guðbjartsson, D. F., Thorleifsson, G., Thorsteinsdottir, U., Stefansson, K. & 7 others, Hattersley, A. T., Walker, M., Morris, A. D., McCarthy, M. I., Palmer, C. N. A., Laakso, M. & Frayling, T. M., Jun 2015, In: Diabetes. 64, 6, p. 2279-85 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Comparison of RNA-seq and microarray-based models for clinical endpoint prediction

    Zhang, W., Yu, Y., Hertwig, F., Thierry-Mieg, J., Zhang, W., Thierry-Mieg, D., Wang, J., Furlanello, C., Devanarayan, V., Cheng, J., Deng, Y., Hero, B., Hong, H., Jia, M., Li, L., Lin, S. M., Nikolsky, Y., Oberthuer, A., Qing, T., Su, Z. & 56 others, Volland, R., Wang, C., Wang, M. D., Ai, J., Albanese, D., Asgharzadeh, S., Avigad, S., Bao, W., Bessarabova, M., Brilliant, M. H., Brors, B., Chierici, M., Chu, T., Zhang, J., Grundy, R. G., He, M. M., Hebbring, S., Kaufman, H. L., Lababidi, S., Lancashire, L. J., Li, Y., Lu, X. X., Luo, H., Ma, X., Ning, B., Noguera, R., Peifer, M., Phan, J. H., Roels, F., Rosswog, C., Shao, S., Shen, J., Theissen, J., Tonini, G. P., Vandesompele, J., Wu, P., Xiao, W., Xu, J., Xu, W., Xuan, J., Yang, Y., Ye, Z., Dong, Z., Zhang, K. K., Yin, Y., Zhao, C., Zheng, Y., Wolfinger, R. D., Shi, T., Malkas, L. H., Berthold, F., Wang, J., Tong, W., Shi, L., Peng, Z. & Fischer, M., 2015, In: Genome Biology (Online Edition). 16, 12 p., 133.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Diabetologia at 50: celebrating half a century of progress in diabetes research and care

    Zierath, Juleen R, Aug 2015, In: Diabetologia. 58, 8, p. 1685-7 3 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  36. Published

    Looking Ahead Perspective: Where Will the Future of Exercise Biology Take Us?

    Zierath, Juleen R & Wallberg-Henriksson, H., 7 Jul 2015, In: Cell Metabolism. 22, 1, p. 25-30 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Is the adiposity-associated FTO gene variant related to all-cause mortality independent of adiposity? Meta-analysis of data from 169,551 Caucasian adults

    Zimmermann, E., Ängquist, L. H., Mirza, S. S., Zhao, J. H., Chasman, D. I., Fischer, K., Qi, Q., Smith, A. V., Thinggaard, M., Jarczok, M. N., Nalls, M. A., Trompet, S., Timpson, N. J., Schmidt, B., Jackson, A. U., Lyytikäinen, L. P., Verweij, N., Mueller-Nurasyid, M., Vikström, M., Marques-Vidal, P. & 31 others, Wong, A., Meidtner, K., Middelberg, R. P., Strawbridge, R. J., Christiansen, L., Kyvik, K. O., Hamsten, A., Jääskeläinen, T., Tjønneland, A., Eriksson, J. G., Whitfield, J. B., Boeing, H., Hardy, R., Vollenweider, P., Leander, K., Peters, A., van der Harst, P., Kumari, M., Lehtimäki, T., Meirhaeghe, A., Tuomilehto, J., Jöckel, K., Ben-Shlomo, Y., Sattar, N., Baumeister, S. E., Davey Smith, G., Casas, J. P., Houston, D. K., März, W., Sørensen, Thorkild I.A. & FTO-Mortality Collaborating Group, F. C. G., Apr 2015, In: Obesity Reviews. 16, 4, p. 327-40 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Body mass index in school-aged children and the risk of routinely diagnosed non-alcoholic fatty liver disease in adulthood: a prospective study based on the Copenhagen School Health Records Register

    Zimmermann, E., Gamborg, M., Holst, C., Baker, J. L., Sørensen, Thorkild I.A. & Berentzen, T. L., 2015, In: B M J Open. 5, p. 1-8 8 p., e006998.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Sex Differences in the Association Between Birth Weight and Adult Type 2 Diabetes

    Zimmermann, E., Gamborg, Michael Orland, Sørensen, Thorkild I.A. & Baker, J. L., Dec 2015, In: Diabetes. 64, 12, p. 4220-4225 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Bile acid mediated effects on gut integrity and performance of early-weaned piglets

    de Diego-Cabero, N., Mereu, A., Menoyo, D., Holst, Jens Juul & Ipharraguerre, I. R., 2015, In: B M C Veterinary Research. 11, 1, p. 1-8 8 p., 111.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Galdesten og komplikationer i forbindelse med galdestenssygdom hos statinbehandlede

    roepstorff, S. & pjx571, pjx571, 26 Oct 2015, In: Ugeskrift for Laeger.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    A novel common variant in DCST2 is associated with length in early life and height in adulthood

    van der Valk, R. J. P., Kreiner-Møller, E., Kooijman, M. N., Guxens, M., Stergiakouli, E., Sääf, A., Bradfield, J. P., Geller, F., Hayes, M. G., Cousminer, D. L., Körner, A., Thiering, E., Curtin, J. A., Myhre, R., Huikari, V., Joro, R., Kerkhof, M., Warrington, N. M., Pitkänen, N., Ntalla, I. & 31 others, Horikoshi, M., Veijola, R., Freathy, R. M., Teo, Y., Barton, S. J., Evans, D. M., Kemp, J. P., St Pourcain, B., Ring, S. M., Davey Smith, G., Bergström, A., Kull, I., Hakonarson, H., Mentch, F. D., Bisgaard, H., Chawes, Bo Lund Krogsgaard, Stokholm, Jakob, Waage, J., Eriksen, P., Sevelsted, A., Melbye, M., van Duijn, C. M., Medina-Gomez, C., Hofman, A., de Jongste, J. C., Taal, H. R., Uitterlinden, A. G., Armstrong, L. L., Pers, Tune H, Bønnelykke, Klaus & Early Genetics and Lifecourse Epidemiology (EAGLE) Consortium, E. G. A. L. E. (. C., 15 Feb 2015, In: Human Molecular Genetics. 24, 4, p. 1155-68 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Critical role of somatostatin receptor 2 in the vulnerability of the central noradrenergic system: new aspects on Alzheimer's disease

    Ádori, C., Glück, L., Barde, S., Yoshitake, T., Kovacs, G. G., Mulder, J., Maglóczky, Z., Havas, L., Bölcskei, K., Mitsios, N., Uhlén, M., Szolcsányi, J., Kehr, J., Rönnbäck, A., Schwartz, Thue W., Rehfeld, Jens Frederik, Harkany, T., Palkovits, M., Schulz, S. & Hökfelt, T., Apr 2015, In: Acta Neuropathologica. 129, 4, p. 541-63 23 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Increased All-Cause Mortality in Patients With Type 1 Diabetes and High-Expression Mannan-Binding Lectin Genotypes: A 12-Year Follow-up Study

    Østergaard, J. A., Thiel, S., Lajer, M., Steffensen, R., Parving, H., Flyvbjerg, A., Rossing, Peter, Tarnow, L. & Hansen, T. K., Oct 2015, In: Diabetes Care. 38, 10, p. 1898-1903 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Postprandial incretin and islet hormone responses and dipeptidyl-peptidase 4 enzymatic activity in patients with maturity onset diabetes of the young

    Østoft, S. H., Bagger, J. I., Hansen, Torben, Hartmann, Bolette, Pedersen, Oluf Borbye, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 1 Aug 2015, In: European Journal of Endocrinology. 173, 2, p. 205-215 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. 2014
  47. Published

    Childhood body mass index and the risk of prostate cancer in adult men

    Aarestrup, J., Gamborg, Michael Orland, Cook, M. B., Sørensen, Thorkild I.A. & Baker, J. L., 2014, In: B J C. 111, p. 207-212 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Skeletal muscle PGC-1α1 modulates kynurenine metabolism and mediates resilience to stress-induced depression

    Agudelo, L. Z., Femenía, T., Orhan, F., Porsmyr-Palmertz, M., Goiny, M., Martinez-Redondo, V., Correia, J. C., Izadi, M., Bhat, M., Schuppe-Koistinen, I., Pettersson, A. T., Ferreira, D. M. S., Krook, A., Barrès, Romain, Zierath, Juleen R, Erhardt, S., Lindskog, M. & Ruas, J. L., 25 Sep 2014, In: Cell. 159, 1, p. 33-45 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Trends in Parent-Child Correlations of Childhood Body Mass Index during the Development of the Obesity Epidemic

    Ajslev, T. A., Ängquist, Lars, Silventoinen, K., Baker, J. L. & Sørensen, Thorkild I.A., 2014, In: PLOS ONE. 9, 10, p. 1-8 8 p., e109932.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Hyperglucagonaemia analysed by glucagon sandwich ELISA: nonspecific interference or truly elevated levels?

    Albrechtsen, Nicolai Jacob Wewer, Hartmann, Bolette, Veedfald, Simon, Windeløv, Johanne Agerlin, Plamboeck, A., Bojsen-Møller, K. N., Idorn, T., Feldt-Rasmussen, Bo, Knop, Filip Krag, Vilsbøll, T., Madsbad, Sten, Deacon, Carolyn F. & Holst, Jens Juul, 3 Jun 2014, In: Diabetologia. 57, 9, p. 1919-1926 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Targeting the intestinal L-cell for obesity and type 2 diabetes treatment

    Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Deacon, Carolyn F. & Holst, Jens Juul, 1 Jan 2014, In: Expert Review of Endocrinology & Metabolism. 9, 1, p. 61-72 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Pleiotropic effects of HNF1A rs1183910 in a population-based study of 60,283 individuals

    Allin, K. H. & Nordestgaard, Børge, Apr 2014, In: Diabetologia. 57, 4, p. 729-737 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Genomet og diabetes

    Allin, K. H., Hansen, Torben & Pedersen, Oluf Borbye, 10 Nov 2014, In: Ugeskrift for Laeger. 176, 23, p. 2176-2179 V06140337.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Type 2 diabetes susceptibility gene variants predispose to adult-onset autoimmune diabetes

    Lepola, Mette Andersen, Sterner, M., Forsén, T., Käräjämäki, A., Rolandsson, O., Forsblom, C., Groop, P. H., Lahti, K., Nilsson, P. M., Groop, L. & Tuomi, T., 1 Jan 2014, In: Diabetologia. 57, 9, p. 1859-1868 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Birth weight, childhood BMI and height in relation to mammographic density and breast cancer: Register based cohort study

    Andersen, Zorana Jovanovic, Baker, J. L., Bihrmann, K., Vejborg, I., Sørensen, Thorkild I.A. & Lynge, Elsebeth, Mar 2014, In: European Journal of Cancer. 50, Suppl S2, p. S75-S75 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  56. Published

    Birth weight, childhood body mass index, and height in relation to mammographic density and breast cancer: a register-based cohort study

    Andersen, Zorana Jovanovic, Baker, J. L., Bihrmann, K., Vejborg, I. M. M., Sørensen, Thorkild I.A. & Lynge, Elsebeth, 2014, In: Breast cancer research : BCR. 16, 1, p. 1-11 11 p., R4.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Stata tip 117: graph combine-Combining graphs

    Ängquist, Lars, 2014, In: Stata Journal. 14, 1, p. 221-225

    Research output: Contribution to journalEditorialResearchpeer-review

  58. Published

    Liraglutide as Add-on to Oral Antidiabetic Agents or Insulin in Routine Practice of Patients with Type 2 Diabetes

    Anholm, C., Frandsen, H., Sigfusson, E. C. H., drb459, drb459 & Madsbad, S., 2014, In: Journal of Diabetes Mellitus. 4, 2, p. 148-54 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Interactions of dietary protein and adiposity measures in relation to subsequent changes in body weight and waist circumference

    Ankarfeldt, Mikkel Zöllner, Ängquist, Lars, Jakobsen, M. U., Overvad, K., Tjønneland, A., Halkjær, J., Astrup, A. & Sørensen, Thorkild I.A., 2014, In: Obesity. 22, 9, p. 2097-2103 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Body Characteristics, Dietary Protein and Body Weight Regulation: Reconciling Conflicting Results from Intervention and Observational Studies?

    Ankarfeldt, Mikkel Zöllner, Ängquist, Lars, Stocks, T., Jakobsen, M. U., Overvad, K., Halkjær, J., Saris, W. H. M., Astrup, A. & Sørensen, Thorkild I.A., 2014, In: P L o S One. 9, 7, p. 1-8 8 p., e101134.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Interaction between genetic predisposition to adiposity and dietary protein in relation to subsequent change in body weight and waist circumference

    Ankarfeldt, Mikkel Zöllner, Larsen, S. C., Ängquist, Lars, Husemoen, L. L. N., Roswall, N., Overvad, K., Jakobsen, M. U., Halkjær, J., Tjønneland, A., Linneberg, Allan René, Toft, Ulla Marie Nørgaard, Hansen, Torben, Pedersen, Oluf Borbye, Heitmann, Berit, Astrup, A. & Sørensen, Thorkild I.A., 2014, In: P L o S One. 9, 10, 10 p., e110890.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Defining the role of GLP-1 in the enteroinsulinar axis in type 2 diabetes using DPP-4 inhibition and GLP-1 receptor blockade

    Aulinger, B. A., Bedorf, A., Kutscherauer, G., de Heer, J., Holst, Jens Juul, Göke, B. & Schirra, J., Mar 2014, In: Diabetes. 63, 3, p. 1079-92 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Glucagon responses to increasing oral loads of glucose and corresponding isoglycaemic intravenous glucose infusions in patients with type 2 diabetes and healthy individuals

    Bagger, J. I., Knop, Filip Krag, Lund, Asger Bach, Holst, Jens Juul & Vilsbøll, T., 31 May 2014, In: Diabetologia. 57, 8, p. 1270-25 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    The genome of a Mongolian individual reveals the genetic imprints of Mongolians on modern human populations

    Bai, H., Guo, X., Zhang, D., Narisu, N., Bu, J., Jirimutu, J., Liang, F., Zhao, X., Xing, Y., Wang, D., Li, T., Zhang, Y., Guan, B., Yang, X., Yang, Z., Shuangshan, S., Su, Z., Wu, H., Li, W., Chen, M. & 18 others, Zhu, S., Bayinnamula, B., Chang, Y., Gao, Y., Lan, T., Suyalatu, S., Huang, H., Su, Y., Chen, Y., Li, W., Yang, X., Feng, Q., Wang, J., Yang, H., Wang, J., Wu, Q., Yin, Y. & Zhou, H., 2014, In: Genome Biology and Evolution. 6, 12, p. 3122-3136 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Specificity and sensitivity of commercially available assays for glucagon and oxyntomodulin measurement in humans

    Bak, M. J., Albrechtsen, Nicolai Jacob Wewer, Pedersen, Jens, Hartmann, Bolette, Christensen, M., Vilsbøll, T., Knop, F. K., Deacon, Carolyn F., Dragsted, Lars Ove & Holst, Jens Juul, 2014, In: European Journal of Endocrinology. 170, 4, p. 529-538 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Specificity and sensitivity of commercially available assays for glucagon-like peptide-1 (GLP-1): Implications for GLP-1 measurements in clinical studies

    Bak, M. J., Albrechtsen, Nicolai Jacob Wewer, Pedersen, Jens, Knop, Filip Krag, Vilsbøll, Tina, Jørgensen, N. B., Hartmann, Bolette, Deacon, Carolyn F., Dragsted, Lars Ove & Holst, Jens Juul, 2014, In: Diabetes, Obesity and Metabolism. 16, 11, p. 1155-1164 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    No Effect of Aprotinin (Trasylol) on Degradation of Exogenous and Endogenous Glucagon in Human, Mouse and Rat Plasma

    Bak, M. J., Albrechtsen, Nicolai Jacob Wewer, Hartmann, Bolette, Pedersen, Jens, Christensen, M., Vilsboll, T., Knop, F. K., Deacon, Carolyn F., Dragsted, Lars Ove & Holst, Jens Juul, 2014, In: Journal of Endocrinology and Diabetes. 1, 1, p. 1-5 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Incretin secretion: direct mechanisms

    Balk-Møller, E., Holst, Jens Juul & Kuhre, Rune Ehrenreich, 12 Jun 2014, Diapedia: The living textbook of diabetes. European Association for the Study of Diabetes (EASD), p. 1-3 3 p.

    Research output: Chapter in Book/Report/Conference proceedingEncyclopedia chapterCommunication

  69. Published

    The absence of GH signaling affects the susceptibility to high-fat diet-induced hypothalamic inflammation in male mice

    Baquedano, E., Ruiz-Lopez, A. M., Sustarsic, E. G., Herpy, J., List, E. O., Chowen, J. A., Frago, L. M., Kopchick, J. J. & Argente, J., Dec 2014, In: Endocrinology. 155, 12, p. 4856-67 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Direct assessment of hepatic mitochondrial oxidative and anaplerotic fluxes in humans using dynamic 13C magnetic resonance spectroscopy

    Befroy, D. E., Perry, R. J., Jain, N., Dufour, S., Cline, G. W., Trimmer, J. K., Brosnan, J., Rothman, D. L., Petersen, K. F. & Shulman, G. I., 2014, In: Nature Medicine. 20, 1, p. 98-102 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Du er ikke alene Om bakterier og bevidsthed: Om bevidsthed og bakterier

    Bencard, Adam, 2014, Im-materialitet (bevidsthed). Kirkhoff Eriksen, B. (ed.). Sorø: Sorø Kunstmuseum, Vol. 3. p. 69-78 19 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterCommunication

  72. Published

    Presence in the museum: On metonymies, discontinuity and history without stories

    Bencard, Adam, 2014, In: Museum & Society. 12, 1, p. 29-43 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Effects of hydrolysed casein, intact casein and intact whey protein on energy expenditure and appetite regulation: a randomised, controlled, cross-over study

    Bendtsen, L. Q., Lorenzen, J. K., Gomes, S., Liaset, B., Holst, Jens Juul, Ritz, C., Reitelseder, S., Sjödin, Anders Mikael & Astrup, A., 2014, In: British Journal of Nutrition. 112, 8, p. 1412-1422 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Body mass index in childhood and adult risk of primary liver cancer

    Berentzen, T. L., Gamborg, Michael Orland, Holst, C., Sørensen, Thorkild I.A. & Baker, J. L., Feb 2014, In: Journal of Hepatology. 60, 2, p. 325-30 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    GLUT4 and glycogen synthase are key players in bed rest-induced insulin resistance. Diabetes 2012;61:1090-1099

    Biensø, R. S., Ringholm, S., Kiilerich, K., Aachmann-Andersen, N., Krogh-Madsen, Rikke, Guerra, B., Plomgaard, Peter Stendahl, van Hall, Gerrit, Treebak, Jonas Thue, Saltin, B., Lundby, C., Calbet, J. A. L., Pilegaard, Henriette & Wojtaszewski, Jørgen F P, 2014, In: Diabetes. 63, 9, 1 p., 3159.

    Research output: Contribution to journalComment/debateResearch

  76. Published

    Lactobacillus paracasei subsp paracasei L. casei W8 suppresses energy intake acutely

    Bjerg, A. T., Kristensen, M. B., Ritz, C., Holst, Jens Juul, Rasmussen, C., Leser, T. D., Wellejus, A. & Astrup, A., 2014, In: Appetite. 82, p. 111-118 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Effects of body size and change in body size from infancy through childhood on body mass index in adulthood

    Bjerregaard, L. G., Rasmussen, K. M., Michaelsen, Kim F., Skytthe, A., Mortensen, Erik Lykke, Baker, J. L. & Sørensen, Thorkild I.A., 2014, In: International Journal of Obesity. 38, 10, p. 1305-1311 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Maternal Pre-Pregnancy BMI and Intelligence Quotient (IQ) in 5-Year-Old Children: A Cohort Based Study

    Bliddal, M., Olsen, J., Støvring, H., Eriksen, H. F., Kesmodel, U. S., Sørensen, Thorkild I.A. & Nøhr, E. A., 2014, In: PLOS ONE. 9, 4, p. 1-7 7 p., e94498.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Early enhancements of hepatic and later of peripheral insulin sensitivity combined with increased postprandial insulin secretion contribute to improved glycemic control after Roux-en-Y gastric bypass

    Bojsen-Møller, K. N., Dirksen, C., Jørgensen, N. B., Jacobsen, S. H., Serup, A. K. L., Albers, P. H., Hansen, D. L., Worm, D., Naver, L., Kristiansen, V. B., Wojtaszewski, Jørgen F P, Kiens, Bente, Holst, Jens Juul, Richter, Erik A. & Madsbad, Sten, 2014, In: Diabetes. 63, 5, p. 1725-1737 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    The Genome of the Netherlands: design, and project goals

    Boomsma, D. I., Wijmenga, C., Slagboom, E. P., Swertz, M. A., Karssen, L. C., Abdellaoui, A., Ye, K., Guryev, V., Vermaat, M., van Dijk, F., Francioli, L. C., Hottenga, J. J., Laros, J. F. J., Li, Q., Li, Y., Cao, H., Chen, R., Du, Y., Li, N., Cao, S. & 32 others, van Setten, J., Menelaou, A., Pulit, S. L., Hehir-Kwa, J. Y., Beekman, M., Elbers, C. C., Byelas, H., de Craen, A. J. M., Deelen, P., Dijkstra, M., den Dunnen, J. T., de Knijff, P., Houwing-Duistermaat, J., Koval, V., Estrada, K., Hofman, A., Kanterakis, A., van Enckevort, D., Mai, H., Kattenberg, M., van Leeuwen, E. M., Neerincx, P. B. T., Oostra, B., Rivadeneira, F., Suchiman, E. H. D., Uitterlinden, A. G., Willemsen, G., Wolffenbuttel, B. H., Wang, J., de Bakker, P. I. W., van Ommen, G. & van Duijn, C. M., 2014, In: European Journal of Human Genetics. 22, p. 221-227 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    Dietary intervention modulates the gut microbiota and improves insulin resistance - a randomized controlled trial in obese postmenopausal women

    Brahe, L. K., Le Chatelier, E., Prifti, E., Kennedy, S., Blædel, T., Håkansson, J., Pedersen, Oluf Borbye, Astrup, A., Ehrlich, S. & Larsen, L. H., 2014, In: Obesity Reviews. 15, Suppl. 2, p. 41-42 2 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  82. Published

    META-Life: Biotechnologies, Synthetic Biology, Alife and the Arts

    Bureaud, A. (ed.), Malina, R. (ed.) & Whiteley, Louise (ed.), Jul 2014, (Leonardo).

    Research output: Book/ReportBookpeer-review

  83. Published

    Meta-Life: Biotechnologies, Synthetic Biology, A-Life and the Arts

    Bureaud, A. (ed.), Malina, R. (ed.) & Whiteley, Louise (ed.), 2014, Leonardo/ISAST and MIT Press . 694 p.

    Research output: Book/ReportAnthologypeer-review

  84. Published

    Lysine deacetylase inhibition prevents diabetes by chromatin-independent immunoregulation and β-cell protection

    Christensen, D. P., Gysemans, C., Lundh, M., Dahllöf, M. S., Noesgaard, D., Schmidt, S. F., Mandrup, S., Birkbak, N., Workman, C., Piemonti, L., Blaabjerg, L., Monzani, V., Fossati, G., Mascagni, P., Paraskevas, S., Aikin, R. A., Billestrup, N., Grunnet, L. G., Dinarello, C. A., Mathieu, C. & 1 others, Mandrup-Poulsen, Thomas, 6 Jan 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 3, p. 1055-9 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Functional Screening Identifies miRNAs Influencing Apoptosis and Proliferation in Colorectal Cancer

    Christensen, L. L., Holm, A., Rantala, J., Kallioniemi, O., Rasmussen, M. H., Ostenfeld, M. S., Dagnaes-Hansen, F., Oster, B., Schepeler, T., Tobiasen, H., Thorsen, K., Sieber, O. M., Gibbs, P., Lamy, P., Hansen, T. F., Jakobsen, A., Riising, E. M., Helin, K., Lubinski, J., Hagemann-Madsen, R. & 3 others, Laurberg, S., Orntoft, T. F. & Andersen, C. L., 2014, In: PLOS ONE. 9, 6, p. e96767

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Glucose-dependent Insulinotropic Polypeptide: Blood Glucose Stabilizing Effects in Patients With Type 2 Diabetes

    Christensen, Mikkel Bring, Calanna, S., Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, Mar 2014, In: The Journal of clinical endocrinology and metabolism. 99, 3, p. E418-26 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    GLP-1/glucagon coagonism restores leptin responsiveness in obese mice chronically maintained on an obesogenic diet

    Clemmensen, Christoffer, Chabenne, J., Finan, B., Sullivan, L., Fischer, K., Küchler, D., Sehrer, L., Ograjsek, T., Hofmann, S. M., Schriever, S. C., Pfluger, P. T., Pinkstaff, J., Tschöp, M. H., Dimarchi, R. & Müller, T. D., Apr 2014, In: Diabetes. 63, 4, p. 1422-7 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty

    The ReproGen Consortium, T. R. C., The Early Growth Genetics (EGG) Consortium, T. E. G. G. (. C., The Early Growth Genetics (EGG) Consortium, T. E. G. G. (. C., The ReproGen Consortium, T. R. C. & The GIANT Consortium, T. G. C., 1 Jan 2014, In: Human Molecular Genetics. 23, 16, p. 4452-4464 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age

    Deelen, J., Beekman, M., Uh, H-W., Broer, L., Ayers, K. L., Tan, Q., Kamatani, Y., Bennet, A. M., Tamm, R., Trompet, S., Guðbjartsson, D. F., Flachsbart, F., Rose, G., Viktorin, A., Fischer, K., Nygaard, M., Cordell, H. J., Crocco, P., van den Akker, E. B., Böhringer, S. & 67 others, Helmer, Q., Nelson, C. P., Saunders, G. I., Alver, M., Andersen-Ranberg, K., Breen, M. E., van der Breggen, R., Caliebe, A., Capri, M., Cevenini, E., Collerton, J. C., Dato, S., Davies, K., Ford, I., Gampe, J., Garagnani, P., de Geus, E. J. C., Harrow, J., van Heemst, D., Heijmans, B. T., Heinsen, F., Hottenga, J., Hofman, A., Jeune, B., Jonsson, P. V., Lathrop, M., Lechner, D., Martin-Ruiz, C., Mcnerlan, S. E., Mihailov, E., Montesanto, A., Mooijaart, S. P., Murphy, A., Nohr, E. A., Paternoster, L., Postmus, I., Rivadeneira, F., Ross, O. A., Salvioli, S., Sattar, N., Schreiber, S., Stefánsson, H., Stott, D. J., Tiemeier, H., Uitterlinden, A. G., Westendorp, R. G. J., Willemsen, G., Samani, N. J., Galan, P., Sørensen, Thorkild I.A., Boomsma, D. I., Jukema, J. W., Rea, I. M., Passarino, G., de Craen, A. J. M., Christensen, K., Nebel, A., Stefánsson, K., Metspalu, A., Magnusson, P., Blanché, H., Christiansen, L., Kirkwood, T. B. L., van Duijn, C. M., Franceschi, C., Houwing-Duistermaat, J. J. & Slagboom, P. E., 15 Aug 2014, In: Human Molecular Genetics. 23, 16, p. 4420-4432 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Lessons from whole-exome sequencing in MODYX families

    Dusatkova, P., Fang, M., Pruhova, S., Gjesing, A. P., Cinek, O., Hansen, Torben, Pedersen, Oluf Borbye, Xu, X. & Lebl, J., Jun 2014, In: Diabetes Research and Clinical Practice. 104, 3, p. e72-4 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Glucometabolic hormones and cardiovascular risk markers in antipsychotic-treated patients

    Ebdrup, Bjørn, Knop, Filip Krag, Madsen, A., Mortensen, H. B., Søgaard, B., Holst, Jens Juul, Szecsi, P. B. & Lublin, H., Sep 2014, In: Journal of Clinical Psychiatry. 75, 9, p. e899-905 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Interplay between FGF21 and insulin action in the liver regulates metabolism

    Emanuelli, Brice, Vienberg, S. G., Smyth, G., Cheng, C., Stanford, K. I., Arumugam, Mani, Michael, M. D., Adams, A. C., Kharitonenkov, A. & Kahn, C. R., 3 Feb 2014, In: The Journal of Clinical Investigation. 124, 2, p. 515-27 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Structural basis for constitutive activity and agonist-induced activation of the enteroendocrine fat sensor GPR119

    Engelstoft, M. S., Norn, C., Pedersen, M. H., Holliday, N. D., Elster, L., Lehmann, J., Jones, R. M., Frimurer, Thomas Michael & Schwartz, Thue W., Dec 2014, In: British Journal of Pharmacology. 171, 24, p. 5774-89 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    Defects in TLR3 expression and RNase L activation lead to decreased MnSOD expression and insulin resistance in muscle cells of obese people

    Fabre, O. M. J., Breuker, C., Amouzou, C., Salehzada, T., Kitzmann, M., Mercier, J. & Bisbal, C., 2014, In: Cell Death & Disease. 5, p. 1-11 11 p., e1136.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Circadian enhancers coordinate multiple phases of rhythmic gene transcription in vivo

    Fang, B., Everett, L. J., Jager, J., Briggs, E., Armour, S. M., Feng, D., Roy, A., Gerhart-Hines, Zach, Sun, Z. & Lazar, M. A., 20 Nov 2014, In: Cell. 159, 5, p. 1140-1152 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    The Pentapeptide RM-131 Promotes Food Intake and Adiposity in Wildtype Mice but Not in Mice Lacking the Ghrelin Receptor

    Fischer, K., Finan, B., Clemmensen, Christoffer, van der Ploeg, L. H. T., Tschöp, M. H. & Müller, T. D., 2014, In: Frontiers in Nutrition. 1, p. 31

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    Loss-of-function mutations in SLC30A8 protect against type 2 diabetes

    Flannick, J., Thorleifsson, G., Beer, N. L., Jacobs, S. B. R., Grarup, N., Burtt, N. P., Mahajan, A., Fuchsberger, C., Atzmon, G., Benediktsson, R., Blangero, J., Bowden, D. W., Brandslund, I., Brosnan, J., Burslem, F., Chambers, J., Cho, Y. S., Christensen, C., Douglas, D. A., Duggirala, R. & 31 others, Dymek, Z., Farjoun, Y., Fennell, T., Fontanillas, P., Forsén, T., Gabriel, S., Glaser, B., Gudbjartsson, D. F., Hanis, C., Hansen, Torben, Hreidarsson, A. B., Hveem, K., Ingelsson, E., Isomaa, B., Johansson, S., Jørgensen, T., Jørgensen, M. E., Kathiresan, S., Kong, A., Kooner, J., Kravic, J., Laakso, M., Lee, J., Lind, L., Lindgren, C. M., Linneberg, Allan René, Masson, G., Meitinger, T., Ribel-Madsen, R., Pedersen, Oluf Borbye & Go-T2D Consortium, G. C., Apr 2014, In: Nature Genetics. 46, 4, p. 357-63 7 p.

    Research output: Contribution to journalLetterResearchpeer-review

  98. Published

    Tarmbakterier kan have betydning for overvægt i barnealderen

    Fonvig, C. E., Pihl, A. F., Hansen, Torben, Pedersen, Oluf Borbye & Holm, Jens-Christian, 18 Aug 2014, In: Ugeskrift for Laeger. 176, p. 2-6 5 p., V03140171.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Whole-genome sequence variation, population structure and demographic history of the Dutch population

    Francioli, L. C., Menelaou, A., Pulit, S. L., Van Dijk, F., Palamara, P. F., Elbers, C. C., Neerincx, P. B. T., Ye, K., Guryev, V., Kloosterman, W. P., Deelen, P., Abdellaoui, A., Van Leeuwen, E. M., Van Oven, M., Vermaat, M., Li, M., Laros, J. F. J., Karssen, L. C., Kanterakis, A., Amin, N. & 64 others, Hottenga, J. J., Lameijer, E., Kattenberg, M., Dijkstra, M., Byelas, H., Van Settenl, J., Van Schaik, B. D. C., Bot, J., Nijman, I. J., Renkens, I., Marscha, T., Schonhuth, A., Hehir-Kwa, J. Y., Handsaker, R. E., Polak, P., Sohail, M., Vuzman, D., Hormozdiari, F., Van Enckevort, D., Mei, H., Koval, V., Moed, M. H., Van der Velde, K. J., Rivadeneira, F., Estrada, K., Medina-Gomez, C., Isaacs, A., McCarroll, S. A., Beekrnan, M., De Craen, A. J. M., Suchiman, H. E. D., Hofman, A., Oostra, B., Uitterlinden, A. G., Willemsen, G., Plattee, M., Veldink, J. H., Van den Berg, L. H., Pitts, S. J., Potluri, S., Sundar, P., Cox, D. R., Sunyaev, S. R., Den Dunnen, J. T., Stoneking, M., De Knijff, P., Kayser, M., Li, Q., Li, Y., Du, Y., Chen, R., Cao, H., Li, N., Cao, S., Wang, J., Bovenberg, J. A., Peer, I., Slagboom, P. E., Van Duijn, C. M., Boomsma, D. I., Van Ommen, G. B., De Bakker, P. I. W., Swertz, M. A. & Wijmenga, C., 2014, In: Nature Genetics. 46, 8, p. 818-825 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Effect of high-fat diet on rat myometrium during pregnancy-isolated myometrial mitochondria are not affected

    Gam, C. M. B. F., Mortensen, Ole Hartvig, Qvortrup, Klaus, Damm, Peter & Quistorff, B., 21 Aug 2014, In: Pflügers Archiv - European Journal of Physiology. 467, 7, p. 1539-1549 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  101. Published

    Direct ChIP-bisulfite sequencing reveals a role of H3K27me3 mediating aberrant hypermethylation of promoter CpG islands in cancer cells

    Gao, F., Ji, G., Gao, Z., Han, X., Ye, M., Yuan, Z., Luo, H., Huang, X., Natarajan, K., Wang, J., Yang, H. & Zhang, X., 2014, In: Genomics. 103, 2-3, p. 204-210 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  102. Published

    Marked methylation changes in intestinal genes during the perinatal period of preterm neonates

    Gao, F., Zhang, J., Jiang, Pingping, Gong, D., Wang, J., Xia, Y., Østergaard, M. V., Wang, J. & Sangild, Per Torp, 2014, In: BMC Genomics. 15, 1, 14 p., 716.

    Research output: Contribution to journalJournal articleResearchpeer-review