- 2014
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Evaluation of a target region capture sequencing platform using monogenic diabetes as a study-model
Gao, R., Liu, Y., Gjesing, A. M. P., Hollensted, M., Wan, X., He, S., Pedersen, Oluf Borbye, Yi, X., Wang, J. & Hansen, Torben, 2014, In: B M C Genetics. 15, 9 p., 13.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of GLP-1 on myocardial glucose metabolism in healthy men during normo- or hypoglycemia
Gejl, M., Lerche, S., Mengel, A., Møller, N., Bibby, B. M., Smidt, K., Brock, Birgitte, Søndergaard, H., Bøtker, H. E., Gjedde, Albert, Holst, Jens Juul, Hansen, S. B. & Rungby, J., 2014, In: PLOS ONE. 9, 1, p. 1-10 10 p., e83758.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association analyses identify variants in developmental genes associated with hypospadias
Geller, F., Feenstra, B., Carstensen, L., Pers, Tune H, van Rooij, I. A. L. M., Korberg, I. B., Choudhry, S., Karjalainen, J. M., Schnack, T. H., Hollegaard, M. V., Feitz, W. F. J., Roeleveld, N., Hougaard, D. M., Hirschhorn, J. N., Franke, L., Baskin, L. S., Nordenskjold, A., van der Zanden, L. F. M. & Melbye, M., Sep 2014, In: Nature Genetics. 46, 9, p. 957-+Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High heritability and genetic correlation of intravenous glucose- and tolbutamide-induced insulin secretion among non-diabetic family members of type 2 diabetic patients
Gjesing, A. M. P., Hornbak, M., Allin, K. H., Ekstrøm, Claus Thorn, Urhammer, Søren Asger, Eiberg, Hans Rudolf Lytchoff, Pedersen, Oluf Borbye & Hansen, Torben, Jun 2014, In: Diabetologia. 57, 6, p. 1173-1181 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adenosine activates brown adipose tissue and recruits beige adipocytes via A2A receptors
Gnad, T., Scheibler, S., von Kügelgen, I., Scheele, C., Kilić, A., Glöde, A., Hoffmann, L. S., Reverte-Salisa, L., Horn, P., Mutlu, S., El-Tayeb, A., Kranz, M., Deuther-Conrad, W., Brust, P., Lidell, M. E., Betz, M. J., Enerbäck, S., Schrader, J., Yegutkin, G. G., Müller, C. E. & 1 others, , 18 Dec 2014, In: Nature. 516, 7531, p. 395-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic susceptibility to type 2 diabetes and obesity: from genome-wide association studies to rare variants and beyond
Grarup, N., Sandholt, C. H., Hansen, Torben & Pedersen, Oluf Borbye, Aug 2014, In: Diabetologia. 57, 8, p. 1528-41 14 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Preschool Weight and Body Mass Index in Relation to Central Obesity and Metabolic Syndrome in Adulthood
Graversen, L., Sørensen, Thorkild I.A., Petersen, L., Sovio, U., Kaakinen, M., Sandbaek, A., Laitinen, J., Taanila, A., Pouta, A., Järvelin, M. & Obel, C., 2014, In: PLOS ONE. 9, 3, p. 1-9 9 p., e89986.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stability of the Associations between Early Life Risk Indicators and Adolescent Overweight over the Evolving Obesity Epidemic
Graversen, L., Sørensen, Thorkild I.A., Petersen, L., Sovio, U., Kaakinen, M., Sandbæk, A., Laitinen, J., Taanila, A., Pouta, A., Järvelin, M. & Obel, C., 2014, In: PLOS ONE. 9, 4, p. 1-9 9 p., e95314.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acyl-CoA metabolism and partitioning
Grevengoed, Trisha Jean, Klett, E. L. & Coleman, R. A., 2014, In: Annual Review of Nutrition. 34, p. 1-30 30 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sex-specific effects of naturally occurring variants in the dopamine receptor D2 locus on insulin secretion and Type 2 diabetes susceptibility
Guigas, B., de Leeuw van Weenen, J. E., van Leeuwen, N., Simonis-Bik, A. M., van Haeften, T. W., Nijpels, G., Houwing-Duistermaat, J. J., Beekman, M., Deelen, J., Havekes, L. M., Penninx, B. W. J. H., Vogelzangs, N., van 't Riet, E., Dehghan, A., Hofman, A., Witteman, J. C., Uitterlinden, A. G., Grarup, N., Jørgensen, T., Witte, D. R. & 15 others, , Aug 2014, In: Diabetic Medicine. 31, 8, p. 1001-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of IL-6 on the insulin sensitivity in patients with type 2 diabetes
Harder-Lauridsen, N. M., Krogh-Madsen, Rikke, Holst, Jens Juul, Plomgaard, P., Leick, L., Pedersen, Bente Klarlund & Fischer, C. P., 1 Apr 2014, In: American Journal of Physiology: Endocrinology and Metabolism. 306, 7, p. E769-78 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Distal gastrectomy in pancreaticoduodenectomy is associated with accelerated gastric emptying, enhanced postprandial release of GLP-1, and improved insulin sensitivity
Harmuth, S., Wewalka, M., Holst, Jens Juul, Nemecek, R., Thalhammer, S., Schmid, R., Sahora, K., Gnant, M. & Miholić, J., Jan 2014, In: Journal of Gastrointestinal Surgery. 18, 1, p. 52-9 8 p.Research output: Contribution to journal › Conference article › Research › peer-review
- Published
Effects of concentrated arabinoxylan and β-glucan compared with refined wheat and whole grain rye on glucose and appetite in subjects with the metabolic syndrome: a randomized study
Hartvigsen, M. L., Gregersen, S., Lærke, H. N., Holst, Jens Juul, Bach Knudsen, K. E. & Hermansen, K., Jan 2014, In: European Journal of Clinical Nutrition. 68, 1, p. 84-90 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Postprandial effects of test meals including concentrated arabinoxylan and whole grain rye in subjects with the metabolic syndrome: a randomised study
Hartvigsen, M. L., Lærke, H. N., Overgaard, A., Holst, Jens Juul, Bach Knudsen, K. E. & Hermansen, K., May 2014, In: European Journal of Clinical Nutrition. 68, 5, p. 567-74 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Probabilistic Genome-Wide Gene Reading Frame Sequence Model
Have, C. T. & Mørk, S., Apr 2014. 12 p.Research output: Contribution to conference › Paper › Research › peer-review
- Published
Identification of Mislabeled Samples and Sample Mix-ups in Genotype Data using Barcode Genotypes
Have, C. T., Appel, E. V. R., Grarup, N., Hansen, Torben & Bork-Jensen, J., 2014, In: International Journal of Bioscience, Biochemistry and Bioinformatics. 4, 5, p. 355-360 5 p., 370.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acute and perinatal programming effects of a fat-rich diet on rat muscle mitochondrial function and hepatic lipid accumulation
Hellgren, L. I., Jensen, R. I., Waterstradt, M. S. G., Quistorff, B. & Lauritzen, Lotte, 2014, In: Acta Obstetricia et Gynecologica Scandinavica. 93, 11, p. 1170-1180 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Severe Maternal Stress Exposure Due to Bereavement before, during and after Pregnancy and Risk of Overweight and Obesity in Young Adult Men: A Danish National Cohort Study
Hohwü, L., Li, J., Olsen, J., Sørensen, Thorkild I.A. & Obel, C., 2014, In: PLOS ONE. 9, 5, p. 1-7 e97490.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A combined analysis of 48 type 2 diabetes genetic risk variants shows no discriminative value to predict time to first prescription of a glucose lowering drug in Danish patients with screen detected type 2 diabetes.
Hornbak, M., Allin, K. H., Jensen, M. L., Lau, C. J., Witte, D. R., Jørgensen, M. E., Sandbæk, A., Lauritzen, T., Andersson, Åsa, Pedersen, Oluf Borbye & Hansen, Torben, 2014, In: PloS One. 9, 8, 10 p., e104837.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Do rapid BMI growth in childhood and early-onset obesity offer cardiometabolic protection to obese adults in mid-life? Analysis of a longitudinal cohort study of Danish men
Howe, L. D., Zimmermann, E., Weiss, R. & Sørensen, Thorkild I.A., 2014, In: B M J Open. 4, 4, p. 1-10 10 p., e004827.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
R package for Non-sex-of-parent-specific Transmission Ratio Distortion
Huang, L. O., 2014Research output: Non-textual form › Computer programme › Research
- Published
MTHFR C677T genotype and cardiovascular risk in a general population without mandatory folic acid fortification
Husemoen, L. L. N., Skaaby, T., Jørgensen, T., Thuesen, B. H., Fenger, M., Grarup, N., Sandholt, C. H., Hansen, Torben, Pedersen, Oluf Borbye & Linneberg, Allan René, 24 Jan 2014, In: European Journal of Nutrition. 53, 7, p. 1549-59 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Two randomized cross-over trials assessing the impact of dietary gluten or wholegrain on the gut microbiome and host metabolic health
Ibrügger, S., Gøbel, R. J., drb459, drb459, Licht, T. R., Frøkiær, Hanne, Linneberg, Allan René, Hansen, Torben, Gupta, R., Pedersen, Oluf Borbye, Kristensen, M. B. & Lauritzen, Lotte, 2014, In: Journal of Clinical Trials. 4, 4, 9 p., 1000178.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Safety and efficacy of liraglutide in patients with type 2 diabetes and end-stage renal disease: an investigator-initiated, randomised, placebo-controlled trial
Idorn, T., Knop, Filip Krag, Jorgensen, M. B., Jensen, T., Resuli, M., Hansen, P. M., Christensen, Karl Bang, Holst, Jens Juul, Hornum, M. & Feldt-Rasmussen, B., Sep 2014, In: Diabetologia. 57, 1 supplement, p. S370-S371 909.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Elimination and degradation of glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in patients with end-stage renal disease
Idorn, T., Knop, Filip Krag, Jørgensen, M. B., Christensen, Mikkel Bring, Holst, Jens Juul, Hornum, Mads & Feldt-Rasmussen, Bo, 8 Apr 2014, In: The Journal of clinical endocrinology and metabolism. 99, 7, p. 2457-66 10 p., jc20133809.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Postprandial responses of incretin and pancreatic hormones in non-diabetic patients with end-stage renal disease
Idorn, T., Knop, Filip Krag, Jørgensen, M., Holst, Jens Juul, Hornum, Mads & Feldt-Rasmussen, Bo, Jan 2014, In: Nephrology, Dialysis, Transplantation. 29, 1, p. 119-27 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The authors reply
Idorn, T., Knop, Filip Krag, Jørgensen, M., Holst, Jens Juul, Hornum, Mads & Feldt-Rasmussen, Bo, Jan 2014, In: Kidney International. 85, 1, p. 212-3 2 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Therapies for inter-relating diabetes and obesity - GLP-1 and obesity
Iepsen, E. P. W., Torekov, Signe Sørensen & Holst, Jens Juul, Dec 2014, In: Expert Opinion on Pharmacotherapy. 15, 17, p. 2487-500 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High saturated fatty acid intake induces insulin secretion by elevating gastric inhibitory polypeptide levels in healthy individuals
Itoh, K., Moriguchi, R., Yamada, Y., Fujita, M., Yamato, T., Oumi, M., Holst, Jens Juul & Seino, Y., Aug 2014, In: Nutrition Research. 34, 8, p. 653-60 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Young men with low birthweight exhibit decreased plasticity of genome-wide muscle DNA methylation by high-fat overfeeding
Jacobsen, S. C., Gillberg, L., Bork-Jensen, J., Ribel-Madsen, R., Lara, E., Calvanese, V., Ling, C., Fernandez, A. F., Fraga, M. F., Poulsen, P., Brøns, C. & Vaag, Allan, 26 Feb 2014, In: Diabetologia. 57, 6, p. 1154-1158 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Behavioral changes and dopaminergic dysregulation in mice lacking the nuclear receptor rev-erbα
Jager, J., Timothy O'Brien, W., Manlove, J., Krizman, E. N., Fang, B., Gerhart-Hines, Zach, Robinson, M. B., Klein, P. S. & Lazar, M. A., 2014, In: Molecular Endocrinology. 28, 4, p. 490-498 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Does prenatal exposure to vitamin D-fortified margarine and milk alter birth weight? A societal experiment
Jensen, C. B., Berentzen, T. L., Gamborg, Michael Orland, Sørensen, Thorkild I.A. & Heitmann, B. L., 14 Sep 2014, In: British Journal of Nutrition. 112, 5, p. 785-793 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification and characterization of human brown adipose tissue (BAT) content and metabolism in adults using [18F]-FDG PET/MR – a pilot study
Johannesen, H. H., Löfgren, J., Donkin, I., Hansen, A. E., Loft, A., Højgaard, Liselotte & Kjær, Andreas, Jul 2014, In: E J N M M I Physics. 1, Suppl 1, 3 p., A68.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Similar weight-adjusted insulin secretion and insulin sensitivity in short-duration late autoimmune diabetes of adulthood (LADA) and Type 2 diabetes: Action LADA 8
Juhl, C. B., Bradley, U., Holst, Jens Juul, Leslie, R. D., Yderstraede, K. B., Hunter, S. & Action LADA Consortium, A. L. C., 15 Mar 2014, In: Diabetic Medicine. 31, 8, p. 941-945Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A 25-year-old woman with type 2 diabetes and liver disease
Junker, A. E., Gluud, Lise Lotte, Pedersen, J., Langhoff, J. L., Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, T., 2014, In: Case Reports in Gastroenterology. 8, 3, p. 398-403 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Aberrant expression of miR-218 and miR-204 in human mesial temporal lobe epilepsy and hippocampal sclerosis-Convergence on axonal guidance
Kaalund, S. S., Venø, M. T., Bak, M., Møller, R. S., Laursen, H., Madsen, F., Broholm, H., Quistorff, B., Uldall, P., Tommerup, Niels, Kauppinen, S., Sabers, A., Fluiter, K., Møller, L. B., Nossent, Anne Yaël, Silahtaroglu, Asli, Kjems, J., Aronica, E. & Tümer, Asuman Zeynep, Dec 2014, In: Epilepsia. 55, 12, p. 2017-2027 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanisms behind the superior effects of interval vs continuous training on glycaemic control in individuals with type 2 diabetes: a randomised controlled trial
Karstoft, K., Winding, K., Knudsen, S. H., James, N. G., Scheel, M. M., Olesen, J., Holst, Jens Juul, Pedersen, Bente Klarlund & Solomon, T., 2014, In: Diabetologia. 57, 10, p. 2081-2093 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Altered promoter methylation of PDK4, IL1 B, IL6, and TNF after Roux-en Y gastric bypass
Kirchner, H., Nylen, C., Laber, S., Barrès, Romain, Yan, J., Krook, A., Zierath, Juleen R & Näslund, E., 28 Jan 2014, In: Surgery for Obesity and Related Diseases. 10, 4, p. 671-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
How do pregnancy-related weight changes and breastfeeding relate to maternal weight and BMI-adjusted waist circumference 7 y after delivery? Results from a path analysis
Kirkegaard, H., Stovring, H., Rasmussen, K. M., Abrams, B., Sørensen, Thorkild I.A. & Nohr, E. A., Feb 2014, In: The American Journal of Clinical Nutrition. 99, 2, p. 312-319 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Prospective Study of Height and Body Mass Index in Childhood, Birth Weight, and Risk of Adult Glioma Over 40 Years of Follow-up
Kitahara, C. M., Gamborg, Michael Orland, Rajaraman, P., Sørensen, Thorkild I.A. & Baker, J. L., 2014, In: American Journal of Epidemiology. 180, 8, p. 821-829 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Childhood Height and Body Mass Index Were Associated with Risk of Adult Thyroid Cancer in a Large Cohort Study
Kitahara, C. M., Gamborg, Michael Orland, Berrington de González, A., Sørensen, Thorkild I.A. & Baker, J. L., 1 Jan 2014, In: Cancer Research. 74, 1, p. 235-242 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No genetic footprints of the fat mass and obesity associated (FTO) gene in human plasma 1H CPMG NMR metabolic profiles
Kjeldahl, K., Rasmussen, Morten Arendt, Hasselbalch, A. L., Kyvik, K. O., Christiansen, L., Rezzi, S., Kochhar, S., Sørensen, Thorkild I.A. & Bro, Rasmus, 2014, In: Metabolomics. 10, 1, p. 132–140 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Anti-inflammatory properties of a novel peptide interleukin 1 receptor antagonist
Klementiev, B., Li, S., Korshunova, Irina, Dmytriyeva, O., Pankratova, Stanislava, Walmod, P. S., Kjær, L. K., Dahllöf, M. S., Lundh, M., Christensen, D. P., Mandrup-Poulsen, Thomas, Bock, E. & Berezin, V., 2014, In: Journal of Neuroinflammation. 11, 1, p. 27Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Unprecedented high insulin secretion in a healthy human subject after intravenous glucagon-like peptide-1: a case report
Knop, Filip Krag, Lund, Asger Bach, Madsbad, Sten, Holst, Jens Juul, Krarup, T. & Vilsbøll, T., 2014, In: BMC Research Notes. 7, p. 1-6 6 p., 326.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Circulating sCD36 is associated with unhealthy fat distribution and elevated circulating triglycerides in morbidly obese individuals
Knøsgaard, L., Thomsen, S. B., Støckel, M., drb459, drb459 & Handberg, A., 2014, In: Nutrition and Diabetes. 4, 6 p., e114.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: rationale and design of the epidemiological studies within the IMI DIRECT Consortium: Diabetologia
Koivula, R., Heggie, A., Barnett, A., Cederberg, H., Hansen, T. H., Koopman, A., Ridderstråle, M., Rutters, F., Vestergaard, H., Gupta, R., Herrgård, S., Heymans, M., Perry, M., Rauh, S., Siloaho, M., Teare, H. A., Thorand, B., Bell, J., Brunak, S., Frost, G. & 13 others, , 2014, In: Diabetologia. 57, 6, p. 1-11 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evaluation of growth hormone (GH) action in mice: Discovery of GH receptor antagonists and clinical indications
Kopchick, J. J., List, E. O., Kelder, B., Gosney, E. S. & Berryman, D. E., 5 Apr 2014, In: Molecular and Cellular Endocrinology. 386, 1-2, p. 34-45 12 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Pleiotropic genes for metabolic syndrome and inflammation
Kraja, A. T., Chasman, D. I., North, K. E., Reiner, A. P., Yanek, L. R., Oskari Kilpeläinen, T., Smith, J. A., Dehghan, A., Dupuis, J., Johnson, A. D., Feitosa, M. F., Tekola-Ayele, F., Chu, A. Y., Nolte, I. M., Dastani, Z., Morris, A., Pendergrass, S. A., Sun, Y. V., Ritchie, M. D., Vaez, A. & 31 others, , 2014, In: Molecular Genetics and Metabolism. 112, 4, p. 317-38 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Two weeks of metformin treatment induces AMPK dependent enhancement of insulin-stimulated glucose uptake in mouse soleus muscle
Kristensen, Jonas Møller, Treebak, Jonas Thue, Schjerling, Peter, Goodyear, L., Wojtaszewski, J. F. P. & Wojtaszewski, Jørgen F P, 2014, In: American Journal of Physiology: Endocrinology and Metabolism. 306, 10, p. E1099-E1109 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Advances in GPCR modeling evaluated by the GPCR Dock 2013 assessment: meeting new challenges
Kufareva, I., Katritch, V., Biggin, P., Kim, M., Park, K., Jung, S. W., Cho, A. E., Sands, Z. A., Ostopovici-Halip, L., Bologa, C. G., Norn, C., Brylinski, M., Skolnick, J., Keränen, H., Lenselink, B. E., Van Westen, G., Overington, J. P., De Teráán, H. G., Isberg, V., Fidom, K. M. & 96 others, , 2014, In: Structure. 22, 8, p. 1120-1139 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fructose stimulates GLP-1 but not GIP secretion in mice, rats, and humans
Kuhre, Rune Ehrenreich, Gribble, F. M., Hartmann, Bolette, Reimann, F., Windeløv, Johanne Agerlin, Rehfeld, Jens Frederik & Holst, Jens Juul, 1 Apr 2014, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 306, 7, p. G622-30 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1 Amidation Efficiency Along the Length of the Intestine in Mice, Rats and Pigs and in GLP-1 Secreting Cell Lines
Kuhre, Rune Ehrenreich, Albrechtsen, Nicolai Jacob Wewer, Windeløv, Johanne Agerlin, Svendsen, B., Hartmann, Bolette & Holst, Jens Juul, 31 Jan 2014, In: Peptides. 55, p. 52-57 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucose Stimulates GLP-1 Secretion from Isolated Perfused Rat Small Intestine by SGLT1 and GLUT2 Mediated Uptake, Causing V-gated Calcium Channel Activation
Kuhre, Rune Ehrenreich, Frost, C. R., Svendsen, B. & Holst, Jens Juul, Jun 2014, In: Diabetes. 63, suppl 1, p. A491 1 p., Abstract no 1915-P.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Pancreatic effects of GLP-1
Kuhre, Rune Ehrenreich, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 22 Dec 2014, Diapedia: The Living Textbook of Diabetes. European Association for the Study of Diabetes (EASD)Research output: Chapter in Book/Report/Conference proceeding › Encyclopedia chapter › Communication
- Published
Gene-lifestyle interaction and type 2 diabetes: the EPIC interact case-cohort study
Langenberg, C., Sharp, S. J., Franks, P. W., Scott, R. A., Deloukas, P., Forouhi, N. G., Froguel, P., Groop, L. C., Hansen, T., Palla, L., Pedersen, O., Schulze, M. B., Tormo, M-J., Wheeler, E., Agnoli, C., Arriola, L., Barricarte, A., Boeing, H., Clarke, G. M., Clavel-Chapelon, F. & 27 others, , 2014, In: P L o S Medicine (Print). 11, 5, 14 p., e1001647.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
AMPK controls exercise endurance, mitochondrial oxidative capacity, and skeletal muscle integrity
Lantier, L., Fentz, J., Mounier, R., Leclerc, J., Treebak, Jonas Thue, Pehmøller, C. K., Sanz, N., Sakakibara, I., Saint-Amand, E., Rimbaud, S., Maire, P., Marette, A., Ventura-Clapier, R., Ferry, A., Wojtaszewski, Jørgen F P, Foretz, M. & Viollet, B., 2014, In: F A S E B Journal. 28, 7, p. 3211-3224 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Does a GLP-1 receptor agonist change glucose tolerance in patients treated with antipsychotic medications? Design of a randomised, double-blinded, placebo-controlled clinical trial
Larsen, J. R., Vedtofte, L., Holst, Jens Juul, Oturai, P., Kjær, Andreas, Corell, C. U., Vilsbøll, T. & Fink-Jensen, Anders, 2014, In: B M J Open. 4, 3, p. 1-9 9 p., e004227.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dietary ascorbic acid and subsequent change in body weight and waist circumference: associations may depend on genetic predisposition to obesity - a prospective study of three independent cohorts
Larsen, S. C., Ängquist, Lars, Ahluwalia, Tarun Veer Singh, Skaaby, T., Roswall, N., Tjønneland, A., Halkjær, J., Overvad, K., Pedersen, Oluf Borbye, Hansen, Torben, Linneberg, Allan René, Husemoen, L. L. N., Toft, Ulla Marie Nørgaard, Heitmann, B. L. & Sørensen, Thorkild I.A., 2014, In: Nutrition Journal. 13, p. 1-11 11 p., 43.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interaction between genetic predisposition to obesity and dietary calcium in relation to subsequent change in body weight and waist circumference
Larsen, S. C., Ängquist, Lars, Ahluwalia, Tarun Veer Singh, Skaaby, T., Roswall, N., Tjønneland, A., Halkjær, J., Overvad, K., Pedersen, Oluf Borbye, Hansen, Torben, Linneberg, Allan René, Husemoen, L. L. N., Toft, Ulla Marie Nørgaard, Heitmann, Berit & Sørensen, Thorkild I.A., Apr 2014, In: The American Journal of Clinical Nutrition. 99, 4Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased metabolic flexibility and complexity in a long-lived growth hormone insensitive mouse model
Lee Hong, S., Longo, K. A., Gosney, E. & Kopchick, J. J., 17 Mar 2014, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 69 A, 3, p. 274-281 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Impact of aspirin and statins on long-term survival in patients hospitalized with acute myocardial infarction complicated by heart failure: an analysis of 1706 patients
Lewinter, C., Bland, J. M., Crouch, S., Cleland, J. G. F., Doherty, P., LeWinter, M. M., Køber, Lars Valeur, Hall, A. S. & Gale, C. P., Jan 2014, In: European Journal of Heart Failure. 16, 1, p. 95-102 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of referral for cardiac rehabilitation on survival following acute myocardial infarction: a comparison survival in two cohorts collected in 1995 and 2003
Lewinter, C., Bland, J. M., Crouch, S., Doherty, P., Lewin, R. J., Køber, Lars Valeur, Hall, A. S. & Gale, C. P., Feb 2014, In: European Journal of Preventive Cardiology. 21, 2, p. 163-171 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An integrated catalog of reference genes in the human gut microbiome
Li, J., Jia, H., Cai, X., Zhong, H., Feng, Q., Sunagawa, S., Arumugam, M., Kultima, J. R., Prifti, E., Nielsen, T., Juncker, A., Manichanh, C., Chen, B., Zhang, W., Levenez, F., Wang, J., Xu, X., Xiao, L., Liang, S., Zhang, D. & 17 others, , 2014, In: Nature Biotechnology. 32, 8, p. 834-845 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variation and association to diabetes in 2000 full mtDNA sequences mined from an exome study in a Danish population
Li, S., Besenbacher, S., Li, Y., Kristiansen, Karsten, Grarup, N., Albrechtsen, Anders, Sparsø, T. H., Korneliussen, Thorfinn Sand, Hansen, Torben, Wang, J., Nielsen, Rasmus, Pedersen, Oluf Borbye, Bolund, L. & Schierup, M. H., 2014, In: European Journal of Human Genetics. 22, p. 1040-1045 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
New functions and signaling mechanisms for the class of adhesion G protein-coupled receptors
Liebscher, I., Ackley, B., Araç, D., Ariestanti, D. M., Aust, G., Bae, B., Bista, B. R., Bridges, J. P., Duman, J. G., Engel, F. B., Giera, S., Goffinet, A. M., Hall, R. A., Hamann, J., Hartmann, N., Lin, H-H., Liu, M., Luo, R., Mogha, A., Monk, K. R. & 12 others, , Dec 2014, In: Annals of the New York Academy of Sciences. 1333, p. 43-64 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Whole-genome bisulfite sequencing of multiple individuals reveals complementary roles of promoter and gene body methylation in transcriptional regulation
Lou, S., Lee, H., Qin, H., Li, J., Gao, Z., Liu, X., Chan, L. L., Lam, V. K. L., So, W., Wang, Y., Lok, S., Wang, J., Ma, R. C. W., Tsui, S. K., Chan, J. C. N., Chan, T. & Yip, K. Y., 2014, In: Genome Biology (Online Edition). 15, 7, 21 p., 408.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The incretin effect does not differ in trained and untrained, young, healthy men
Lund, M. T., Dalby, S., Hartmann, Bolette, Helge, Jørn Wulff, Holst, Jens Juul & Dela, Flemming, Mar 2014, In: Acta Physiologica. 210, 3, p. 565-72 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Is it acceptable to use animals to model obese humans? a critical discussion of two arguments against the use of animals in obesity research
Lund, Thomas Bøker, Sørensen, Thorkild I.A., Olsson, I. A. S., Hansen, Axel Kornerup & Sandøe, Peter, May 2014, In: Journal of Medical Ethics. 40, 5, p. 320-324 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The plasticity of NBS resistance genes in sorghum is driven by multiple evolutionary processes
Mace, E., Tai, S., Innes, D., Godwin, I., Hu, W., Campbell, B., Gilding, E., Cruickshank, A., Prentis, P., Wang, J. & Jordan, D., 2014, In: B M C Plant Biology. 14, 14 p., 253.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase
Madiraju, A. K., Erion, D. M., Rahimi, Y., Zhang, X., Braddock, D. T., Albright, R. A., Prigaro, B. J., Wood, J. L., Bhanot, S., MacDonald, M. J., Jurczak, M. J., Camporez, J., Lee, H., Cline, G. W., Samuel, V. T., Kibbey, R. G. & Shulman, G. I., 2014, In: Nature. 510, 7506, p. 542-546 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1 as a Mediator in the Remission of Type 2 Diabetes After Gastric Bypass and Sleeve Gastrectomy Surgery
Madsbad, Sten & Holst, Jens Juul, Oct 2014, In: Diabetes. 63, 10, p. 3172-4 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanisms of changes in glucose metabolism and bodyweight after bariatric surgery
Madsbad, Sten, Dirksen, C. & Holst, Jens Juul, Feb 2014, In: The Lancet Diabetes & Endocrinology. 2, 2, p. 152-64 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Social Inequalities in Obesity Persist in the Nordic Region Despite Its Relative Affluence and Equity
Magnusson, M., Sørensen, Thorkild I.A., Olafsdottir, S., Lehtinen-Jacks, S., Holmen, T. L., Heitmann, Berit & Lissner, L., 2014, In: Current Obesity Reports. 3, p. 1-15 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility
Mahajan, A., Go, M. J., Zhang, W., Below, J. E., Gaulton, K. J., Ferreira, T., Horikoshi, M., Johnson, A. D., Ng, M. C. Y., Prokopenko, I., Saleheen, D., Wang, X., Zeggini, E., Abecasis, G. R., Adair, L. S., Almgren, P., Atalay, M., Aung, T., Baldassarre, D., Balkau, B. & 31 others, , Mar 2014, In: Nature Genetics. 46, 3, p. 234-44 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Consumption of a diet low in advanced glycation end products for 4 weeks improves insulin sensitivity in overweight women
Mark, A. B., Poulsen, M. W., Andersen, S., Andersen, J. M., Bak, M. J., Ritz, C., Holst, Jens Juul, Nielsen, J., de Courten, B., Dragsted, Lars Ove & Bügel, Susanne Gjedsted, 2014, In: Diabetes Care. 37, 1, p. 88-95 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1 responses are heritable and blunted in acquired obesity with high liver fat and insulin resistance
Matikainen, N., Bogl, L. H., Hakkarainen, A., Lundbom, J., Lundbom, N., Kaprio, J., Rissanen, A., Holst, Jens Juul & Pietiläinen, K. H., Jan 2014, In: Diabetes Care. 37, 1, p. 242-51 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MuRF1 activity is present in cardiac mitochondria and regulates reactive oxygen species production in vivo
Mattox, T. A., Young, M. E., Rubel, C. E., Spaniel, C., Rodríguez, J. E., Grevengoed, Trisha Jean, Gautel, M., Xu, Z., Anderson, E. J. & Willis, M. S., Jun 2014, In: Journal of Bioenergetics and Biomembranes. 46, 3, p. 173-87 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variation in genes related to hepatic lipid metabolism and changes in waist circumference and body weight
Meidtner, K., Fisher, E., Ängquist, Lars, Holst, C., Vimaleswaran, K. S., Boer, J. M. A., Halkjær, J., Masala, G., Ostergaard, J. N., Mortensen, L. M., van der A, D. L., Tjønneland, A., Palli, D., Overvad, K., Wareham, N. J., Loos, R. J. F., Sørensen, Thorkild I.A. & Boeing, H., Mar 2014, In: Genes & Nutrition. 9, p. 1-11 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulin resistance alters islet morphology in nondiabetic humans
Mezza, T., Muscogiuri, G., Sorice, G. P., Clemente, G., Hu, J., Pontecorvi, A., Holst, Jens Juul, Giaccari, A. & Kulkarni, R. N., Mar 2014, In: Diabetes. 63, 3, p. 994-1007 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes
Moltke, I., Grarup, N., Jørgensen, M. E., Bjerregaard, P., Treebak, J. T., Fumagalli, M., Korneliussen, T. S., Andersen, M. A., Nielsen, T. S., Krarup, N. T., Gjesing, A. M. P., Zierath, J. R., Linneberg, A., Wu, X., Sun, G., Jin, X., Al-Aama, J., Wang, J., Borch-Johnsen, K., Pedersen, O. & 3 others, , 2014, In: Nature. 512, 7513, p. 190-193 4 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Obesity: Global trends in the prevalence of overweight and obesity
Morgen, C. S. & Sørensen, Thorkild I.A., Sep 2014, In: Nature Reviews Endocrinology. 10, 9, p. 513-514 2 p.Research output: Contribution to journal › Comment/debate › Research
- Published
Timing of motor milestones achievement and development of overweight in childhood: a study within the Danish National Birth Cohort
Morgen, C. S., Nybo Andersen, Anne-Marie, Due, P., Neelon, S. B., Gamborg, Michael Orland & Sørensen, Thorkild I.A., Aug 2014, In: Pediatric Obesity. 9, 4, p. 239-48 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protein-driven inference of miRNA-disease associations
Mørk, S., Pletscher-Frankild, S., Palleja, A., Gorodkin, Jan & Jensen, Lars Juhl, 2014, In: Bioinformatics (Oxford, England). 30, 3, p. 392-397 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functional body composition and related aspects in research on obesity and cachexia: report on the 12th Stock Conference held on 6 and 7 September 2013 in Hamburg, Germany
Müller, M. J., Baracos, V., Bosy-Westphal, A., Dulloo, A. G., Eckel, J., Fearon, K. C. H., Hall, K. D., Pietrobelli, A., Sørensen, Thorkild I.A., Speakman, J., Trayhurn, P., Visser, M. & Heymsfield, S. B., Aug 2014, In: Obesity Reviews. 15, 8, p. 640-656 17 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes
Nielsen, H. B., Almeida, M., Juncker, A., Rasmussen, S., Li, J., Sunagawa, S., Plichta, D. R., Gautier, L., Pedersen, A. G., Le Chatelier, E., Pelletier, E., Bonde, I., Nielsen, T., Manichanh, C., Arumugam, M., Batto, J-M., dos Santos, M. B. Q., Blom, N., Borruel, N., Burgdorf, K. S. & 31 others, , 2014, In: Nature Biotechnology. 32, 8, p. 822–828 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of fetal and neonatal environment on beta cell function and development of diabetes
Nielsen, Jens Høiriis, Haase, T. N., Jaksch, C., Nalla, A., Søstrup, B., Nalla, A. A., Larsen, L., Rasmussen, M., Dalgaard, L. T., Gaarn, L. W., Thams, P., Kofod, H. & Billestrup, Nils, Nov 2014, In: Acta Obstetricia et Gynecologica Scandinavica. 93, 11, p. 1109-22 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Muscle specific miRNAs are induced by testosterone and independently upregulated by age
Nielsen, S., Hvid, T., Kelly, M., Lindegaard, B., Dethlefsen, C., Winding, K., Mathur, N., Schéele, Camilla Charlotte Nielsen, Pedersen, Bente Klarlund & Laye, M. J., 23 Jan 2014, In: Frontiers in Physiology. 4, p. 1-11 11 p., 394.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adipose triglyceride lipase and g0/g1 switch gene 2: approaching proof of concept
Nielsen, Thomas Svava & Møller, N., Mar 2014, In: Diabetes. 63, 3, p. 847-9 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dissecting adipose tissue lipolysis: molecular regulation and implications for metabolic disease
Nielsen, Thomas Svava, Jessen, N., Jørgensen, J. O. L., Møller, N. & Lund, S., Jun 2014, In: Journal of Molecular Endocrinology. 52, 3, p. R199-R222 24 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Altered DNA Methylation and Differential Expression of Genes Influencing Metabolism and Inflammation in Adipose Tissue From Subjects With Type 2 Diabetes
Nilsson, E., Jansson, P. A., Perfilyev, A., Volkov, P., Pedersen, M., Svensson, M. K., Poulsen, P., Ribel-Madsen, R., Pedersen, N. L., Almgren, P., Fadista, J., Rönn, T., Pedersen, Bente Klarlund, Schéele, Camilla Charlotte Nielsen, Vaag, Allan & Ling, C., Sep 2014, In: Diabetes. 63, 9, p. 2962-2976 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucose-dependent insulinotropic polypeptide inhibits bone resorption in humans
Nissen, A., Christensen, Mikkel Bring, Knop, Filip Krag, Vilsbøll, T., Holst, Jens Juul & Hartmann, Bolette, Nov 2014, In: The Journal of clinical endocrinology and metabolism. 99, 11, p. E2325-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Tweeting Museum
Noesgaard, D. & Gerdes, N., 2014, In: Meddelelser om Konservering. 2014, 2, p. 30 31 p.Research output: Contribution to journal › Journal article › Communication
- Published
Gene-physical activity interactions and their impact on diabetes
Kilpeläinen, Tuomas O. & Franks, P. W., 2014, In: Medicine and Sport Science. 60, p. 94-103 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucose-Lowering Effects and Low Risk of Hypoglycemia in Patients With Maturity-Onset Diabetes of the Young When Treated With a GLP-1 Receptor Agonist: A Double-Blind, Randomized, Crossover Trial
Ostoft, S. H., Bagger, J. I., Hansen, Torben, Pedersen, Oluf Borbye, Faber, Jens, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, T., 14 Jun 2014, In: Diabetes Care. 37, 7, p. 1797-1805 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incretin Effect and Glucagon Responses to Oral and Intravenous Glucose in Patients with Maturity Onset Diabetes of the Young - Type 2 and Type 3
Ostoft, S. H., Bagger, J. I., Hansen, Torben, Pedersen, Oluf Borbye, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, T., 27 Mar 2014, In: Diabetes. 63, 8, p. 2838-44 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The melanocortin-4 receptor is expressed in enteroendocrine L cells and regulates the release of peptide YY and glucagon-like peptide 1 in vivo
Panaro, B. L., Tough, I. R., Engelstoft, M. S., Matthews, R. T., Digby, G. J., Møller, C. L., Svendsen, B., Gribble, F., Reimann, F., Holst, Jens Juul, Holst, Birgitte, Schwartz, Thue W., Cox, H. M. & Cone, R. D., 2 Dec 2014, In: Cell Metabolism. 20, 6, p. 1018-29 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Deficiency of cardiac Acyl-CoA synthetase-1 induces diastolic dysfunction, but pathologic hypertrophy is reversed by rapamycin
Paul, D. S., Grevengoed, Trisha Jean, Pascual, F., Ellis, J. M., Willis, M. S. & Coleman, R. A., Jun 2014, In: B B A - Reviews on Cancer. 1841, 6, p. 880-7 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hepatic NAD Metabolism Is Dysregulated By an Excessive Supply of Lipids
Penke, M., Treebak, Jonas Thue, Schuster, S., Gorski, T., Garten, A. & Kiess, W., 2014, In: Endocrine Reviews.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche
Perry, J. R. B., Day, F., Elks, C. E., Sulem, P., Thompson, D. J., Ferreira, T., He, C., Chasman, D. I., Esko, T., Thorleifsson, G., Albrecht, E., Ang, W. Q., Corre, T., Cousminer, D. L., Feenstra, B., Franceschini, N., Ganna, A., Johnson, A. D., Kjellqvist, S., Lunetta, K. L. & 31 others, , 2014, In: Nature. 514, 7520, p. 92-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of hepatic lipids in hepatic insulin resistance and type 2 diabetes
Perry, R. J., Samuel, V. T., Petersen, K. M. F. & Shulmann, G. I., 5 Jun 2014, In: Nature. 510, p. 84-91 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity
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