- 2012
- Published
The Rab-GTPase-activating protein TBC1D1 regulates skeletal muscle glucose metabolism
Szekeres, F., Chadt, A., Tom, R. Z., Deshmukh, Atul Shahaji, Chibalin, A. V., Björnholm, M., Al-Hasani, H. & Zierath, Juleen R, 15 Aug 2012, In: American Journal of Physiology: Endocrinology and Metabolism. 303, 4, p. E524-33Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A systems genetics approach identifies genes and pathways for type 2 diabetes in human islets
Taneera, J., Lang, S., Sharma, A., Fadista, J., Zhou, Y., Ahlqvist, E., Jonsson, A. E., Lyssenko, V., Vikman, P., Hansson, O., Parikh, H., Korsgren, O., Soni, A., Krus, U., Zhang, E., Jing, X-J., Esguerra, J. L. S., Wollheim, C. B., Salehi, A., Rosengren, A. & 2 others, , 3 Jul 2012, In: Cell Metabolism. 16, 1, p. 122-34 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-2 (GLP-2) increases net amino acid utilization by the portal-drained viscera of ruminating calves
Taylor-Edwards, C. C., Burrin, D. G., Kristensen, N. B., Holst, Jens Juul, McLeod, K. R. & Harmon, D. L., Dec 2012, In: Animal. 6, 12, p. 1985-97 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modulation in selectivity and allosteric properties of small-molecule ligands for CC-chemokine receptors
Thiele, S., Malmgaard-Clausen, M., Engel-Andreasen, J., Steen, A., Rummel, P. C., Nielsen, M. C., Gloriam, David E., Frimurer, Thomas Michael, Ulven, Trond & Rosenkilde, Mette, 27 Sep 2012, In: Journal of Medicinal Chemistry. 55, 18, p. 8164-77 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic variation in the 15q25 nicotinic acetylcholine receptor gene cluster (CHRNA5-CHRNA3-CHRNB4) interacts with maternal self-reported smoking status during pregnancy to influence birth weight
Tyrrell, J., Huikari, V., Christie, J. T., Cavadino, A., Bakker, R., Brion, M-J. A., Geller, F., Paternoster, L., Myhre, R., Potter, C., Johnson, P. C. D., Ebrahim, S., Feenstra, B., Hartikainen, A-L., Hattersley, A. T., Hofman, A., Kaakinen, M., Lowe, L. P., Magnus, P., McConnachie, A. & 24 others, , 2012, In: Human Molecular Genetics. 21, 24, p. 5344-58 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PheVI:09 (Phe6.44) as a sliding microswitch in seven-transmembrane (7TM) G protein-coupled receptor activation
Valentin-Hansen, L., Holst, Birgitte, Frimurer, Thomas Michael, Schwartz, Thue W. & Hansen, L. V., 21 Dec 2012, In: Journal of Biological Chemistry. 287, 52, p. 43516-43526 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulin resistance after a 72-h fast is associated with impaired AS160 phosphorylation and accumulation of lipid and glycogen in human skeletal muscle
Vendelbo, M., Clasen, B. F. F., Treebak, Jonas Thue, Møller, L., Krusenstjerna-Hafstrøm, T., Madsen, M., Nielsen, Thomas Svava, Stødkilde-Jørgensen, H., Pedersen, S. B., Jørgensen, J. O. L., Goodyear, L. J., Wojtaszewski, Jørgen F P, Møller, N. & Jessen, N., 2012, In: American Journal of Physiology: Endocrinology and Metabolism. 302, 2, p. E190-E200 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Time-Resolved quantitative phosphoproteomics: New insights into angiotensin-(1-7) signaling networks in human endothelial cells
Verano-Braga, T., Schwämmle, V., Sylvester, M., Passos-Silva, D. G., Peluso, A. A. B., Etelvino, G. M., Santos, R. A. S. & Roepstorff, P., 2012, In: Journal of Proteome Research.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Propionate absorbed from the colon acts as gluconeogenic substrate in a strict carnivore, the domestic cat (Felis catus)
Verbrugghe, A., Hesta, M., Daminet, S., Polis, I., Holst, Jens Juul, Buyse, J., Wuyts, B. & Janssens, G. P. J., Dec 2012, In: Journal of Animal Physiology and Animal Nutrition (Online). 96, 6, p. 1054-64 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adipose-specific deletion of TFAM increases mitochondrial oxidation and protects mice against obesity and insulin resistance
Vernochet, C., Mourier, A., Bezy, O., Macotela, Y., Boucher, J., Rardin, M. J., An, D., Lee, K. Y., Ilkayeva, O. R., Zingaretti, C. M., Emanuelli, Brice, Smyth, G., Cinti, S., Newgard, C. B., Gibson, B. W., Larsson, N. & Kahn, C. R., 5 Dec 2012, In: Cell Metabolism. 16, 6, p. 765-76 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development of obesity and polycystic ovary syndrome in adolescents
Vilmann, L. S., Thisted, E., Baker, J. L. & Holm, Jens-Christian, 2012, In: Hormone Research in Paediatrics. 78, 5-6, p. 269-78 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Attention in a bayesian framework
Whiteley, Louise & Sahani, M., 14 Jun 2012, In: Frontiers in Human Neuroscience. 6, 100Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No body is as it seems
Whiteley, Louise, 29 Jun 2012, In: Science (New York, N.Y.). 336, 6089, p. 1641 1 p.Research output: Contribution to journal › Literature review › Research
- Published
Resisting the Revelatory Scanner: Critical Engagements with fMRI in Popular Media
Whiteley, Louise, 2012, In: BioSocieties. 7, 3, p. 245-272Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Resequencing 50 accessions of cultivated and wild rice yields markers for identifying agronomically important genes
Xu, X., Liu, X., Ge, S., Jensen, J. D., Hu, F., Li, X., Dong, Y., Gutenkunst, R. N., Fang, L., Huang, L., Li, J., He, W., Zhang, G., Zheng, X., Zhang, F., Li, Y., Yu, C., Kristiansen, K., Zhang, X., Wang, J. & 5 others, , 2012, In: Nature Biotechnology. 30, 1, p. 105-111 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Single-cell exome sequencing reveals single-nucleotide mutation characteristics of a kidney tumor: Cell
Xu, X., Hou, Y., Yin, X., Bao, L., Tang, A., Song, L., Li, F., Tsang, S., Wu, K., Wu, H., He, W., Zeng, L., Xing, M., Wu, R., Jiang, H., Liu, X., Cao, D., Guo, G., Hu, X., Gui, Y. & 19 others, , 2012, In: Cell. 148, 5, p. 886-895 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The human small intestinal microbiota is driven by rapid uptake and conversion of simple carbohydrates
Zoetendal, E. G., Raes, J., van den Bogert, B., Arumugam, Mani, Booijink, C. C. G. M., Troost, F. J., Bork, P., Wels, M., de Vos, W. M. & Kleerebezem, M., 2012, In: I S M E Journal. 6, 7, p. 1415-26 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chenodeoxycholic acid reduces intestinal permeability in newly weaned piglets
van der Meer, Y., Gerrits, W. J. J., van den Bosch, M., Holst, Jens Juul, Moreto, M., Buurman, W. A., Kulik, W. & van Kempen, T. A. T. G., Dec 2012, In: Journal of Animal Science. 90 Suppl 4, p. 302-4 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
Childhood overweight after establishment of the gut microbiota: the role of delivery mode, pre-pregnancy weight and early administration of antibiotics
Adeltoft, T. A., Andersen, C. S., Gamborg, Michael Orland, Sørensen, Thorkild I.A. & Riis, J. T., 1 Apr 2011, In: International Journal of Obesity. 35, 4, p. 522-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Common variants in CNDP1 and CNDP2, and risk of nephropathy in type 2 diabetes.
Ahluwalia, Tarun Veer Singh, Lindholm, E. & Groop, L., 15 May 2011, In: Diabetologia.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Uromodulin gene variant is associated with type 2 diabetic nephropathy.
Ahluwalia, Tarun Veer Singh, Groop, L. & Melander, O., 29 Sep 2011, In: Journal of Hypertension.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
C-reactive protein and cancer
Allin, K. H., 2011, Faculty of Health Sciences, University of Copenhagen.Research output: Book/Report › Ph.D. thesis
- Published
Insight into structure and assembly of the nuclear pore complex by utilizing the genome of a eukaryotic thermophile
Amlacher, S., Sarges, P., Flemming, D., van Noort, V., Kunze, R., Devos, D. P., Arumugam, Mani, Bork, P. & Hurt, E., 2011, In: Cell. 146, 2, p. 277-89 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Weight gain in different periods of pregnancy and offspring's body mass index at 7 years of age
Andersen, C. S., Gamborg, M., Sørensen, Thorkild I.A. & Nohr, E. A., 2011, In: International Journal of Pediatric Obesity. 6, 2-2, p. e179-86Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Birth Weight Lowering C-Allele of rs900400 Near LEKR1 and CCNL1 Associates with Elevated Insulin Release following an Oral Glucose Challenge
Andersson, E. A., Harder, M. N., Pilgaard, K., Pisinger, C., Stancáková, A., Kuusisto, J., Grarup, Niels, Færch, K., Poulsen, P., Witte, D. R., Jørgensen, T., Vaag, Allan, Laakso, M., Pedersen, Oluf Borbye & Hansen, Torben, Nov 2011, In: P L o S One. 6, 11, p. e27096 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Enterotypes of the human gut microbiome: [Plus]Corrigendum [Plus]Addendum
Arumugam, M., Raes, J., Pelletier, E., Le Paslier, D., Yamada, T., Mende, D. R., Fernandes, G. R., Tap, J., Bruls, T., Batto, J-M., dos Santos, M. B. Q., Borruel, N., Casellas, F., Fernandez, L., Gautier, L., Hansen, T., Hattori, M., Hayashi, T., Kleerebezem, M., Kurokawa, K. & 31 others, , 2011, In: Nature. 473, 7346, p. 174-180 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon antagonism as a potential therapeutic target in type 2 diabetes
Bagger, J. I., Knop, Filip Krag, Holst, Jens Juul & Vilsbøll, Tina, Nov 2011, In: Diabetes, Obesity and Metabolism. 13, 11, p. 965-971 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impaired regulation of the incretin effect in patients with type 2 diabetes
Bagger, J. I., Knop, Filip Krag, Lund, Asger Bach, drb459, drb459, Holst, Jens Juul & Vilsbøll, Tina, 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 3, p. 737-45 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Obesity research based on the Copenhagen School Health Records Register
Baker, J. L. & Sørensen, Thorkild I.A., 2011, In: Scandinavian Journal of Public Health. Supplement. 39, 7 Suppl, p. 196-200 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bioinformatics-driven identification and examination of candidate genes for non-alcoholic fatty liver disease
Banasik, Karina, Justesen, Johanne Marie, Hornbak, M., Krarup, N. T., Gjesing, A. P., Sandholt, C. H., Søndergaard Jensen, T., Grarup, Niels, Andersson, Åsa, Jørgensen, T., Witte, D. R., Sandbæk, A., Lauritzen, T., Thorens, B., Brunak, Søren, Sørensen, Thorkild I.A., Pedersen, Oluf Borbye & Hansen, Torben, 1 Jan 2011, In: P L o S One. 6, 1, p. e16542Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The FOXO3A rs2802292 G-Allele Associates with Improved Peripheral and Hepatic Insulin Sensitivity and Increased Skeletal Muscle-FOXO3A mRNA Expression in Twins
Banasik, Karina, Ribel-Madsen, R., Gjesing, A. P., Wegner, L., Andersson, Åsa, Poulsen, P., Borglykke, A., Witte, D. R., Pedersen, Oluf Borbye, Hansen, Torben & Vaag, Allan, 1 Jan 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 1, p. E119-24Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DNA methylation in metabolic disorders
Barrès, Romain & Zierath, Juleen R, 1 Apr 2011, In: American Journal of Clinical Nutrition. 93, 4, p. 897S-900Research output: Contribution to journal › Review › Research › peer-review
- Published
Balance og stofskifte: To forestillinger om kroppen i medicinens historie
Bencard, Adam, 2011Research output: Non-textual form › 2D/3D (psysical products) › Communication
- Published
Changes in waist circumference and the incidence of acute myocardial infarction in middle-aged men and women
Berentzen, T. L., Jakobsen, M. U., Stegger, J. G., Halkjaer, J., Tjønneland, A., Sørensen, Thorkild I.A. & Overvad, K., 2011, In: P L o S One. 6, 10, p. e26849Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Changes in waist circumference and the incidence of diabetes in middle-aged men and women
Berentzen, T. L., Jakobsen, M. U., Halkjaer, J., Tjønneland, A., Sørensen, Thorkild I.A. & Overvad, K., 2011, In: P L o S One. 6, 8, p. e23104Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PKCδ regulates hepatic insulin sensitivity and hepatosteatosis in mice and humans
Bezy, O., Tran, T. T., Pihlajamäki, J., Suzuki, R., Emanuelli, Brice, Winnay, J., Mori, M. A., Haas, J., Biddinger, S. B., Leitges, M., Goldfine, A. B., Patti, M. E., King, G. L. & Kahn, C. R., Jun 2011, In: The Journal of Clinical Investigation. 121, 6, p. 2504-17 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Implications of central obesity-related variants in LYPLAL1, NRXN3, MSRA, and TFAP2B on quantitative metabolic traits in adult Danes
Bille, D. S., Banasik, Karina, Justesen, Johanne Marie, Sandholt, C. H., Sandbæk, A., Lauritzen, T., Jørgensen, T., Witte, D. R., Holm, Jens-Christian, Hansen, Torben & Pedersen, Oluf Borbye, 1 Jun 2011, In: P L o S One. 6, 6, p. e20640 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chronic AICAR treatment, but not voluntary exercise training, increases nicotinamide phosphoribosyl transferase (Nampt) protein expression in an AMPK-dependent manner in mouse quadriceps muscle
Brandauer, J. & Treebak, Jonas Thue, 2011, In: FASEB Journal.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of Glucagon-Like Peptide-2 on mesenteric blood flow and cardiac parameters in end-jejunostomy short bowel patients
Bremholm, L., Hornum, Mads, Andersen, U. B., Hartmann, Bolette, Holst, Jens Juul & Jeppesen, Palle Bekker, 2011, In: Regulatory Peptides. 168, 1-3, p. 32-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Counter-regulatory hormone responses to spontaneous hypoglycaemia during treatment with insulin Aspart or human soluble insulin: a double-blinded randomized cross-over study
Brock Jacobsen, I., Vind, B. F., Korsholm, L., Flyvbjerg, A., Frystyk, J., Holst, Jens Juul, Beck-Nielsen, H. & Henriksen, J. E., 2011, In: Acta Physiologica (Print). 202, 3, p. 337-347 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic and environmental influences on oxidative damage assessed in elderly Danish twins
Broedbaek, K., Ribel-Madsen, R., Henriksen, T., Weimann, A., Petersen, M., Andersen, Jon Thor Trærup, Afzal, Shoaib, Hjelvang, B., Roberts, L. J., Vaag, Allan, Poulsen, P. & Poulsen, Henrik Enghusen, 2011, In: Free Radical Biology & Medicine. 50, 11, p. 1488-91 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
LIF is a contraction-induced myokine stimulating human myocyte proliferation
Broholm, C., Laye, M. J., Brandt, C., Vadalasetty, R., Pilegaard, Henriette, Pedersen, Bente Klarlund & Schéele, Camilla Charlotte Nielsen, 2011, In: Journal of Applied Physiology. 111, 1, p. 251-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Child overweight - mothers' competence to take action
Brødsgaard, A., Wagner, L., Peitersen, B., Poulsen, I. & Sørensen, Thorkild I.A., Aug 2011, In: Obesity Facts. 4, 4, p. 305-11 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Maternal and child awareness and expectations of child overweight
Brødsgaard, A., Wagner, L., Peitersen, B., Poulsen, I. & Sørensen, Thorkild I.A., 1 Jan 2011, In: Obesity Facts. 4, 4, p. 297-304 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association studies of novel obesity-related gene variants with quantitative metabolic phenotypes in a population-based sample of 6,039 Danish individuals
Burgdorf, K. S., Gjesing, A. P., Grarup, Niels, Justesen, Johanne Marie, Sandholt, C. H., Witte, D. R., Jørgensen, T., Madsbad, Sten, Hansen, Torben & Pedersen, Oluf Borbye, 28 Sep 2011, In: Diabetologia. 55, 1, p. 105-13 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies of the Association of Arg72Pro of Tumor Suppressor Protein p53 with Type 2 Diabetes in a Combined Analysis of 55,521 Europeans
Burgdorf, K. S., Grarup, Niels, Justesen, Johanne Marie, Harder, M. N., Witte, D. R., Jørgensen, T., Sandbæk, A., Lauritzen, T., Madsbad, Sten, Hansen, Torben, DIAGRAM Consortium, D. C. & Pedersen, Oluf Borbye, 2011, In: P L o S One. 6, 1, p. e15813 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Liraglutide Treatment Is Associated with a Low Frequency and Magnitude of Antibody Formation with No Apparent Impact on Glycemic Response or Increased Frequency of Adverse Events: Results from the Liraglutide Effect and Action in Diabetes (LEAD) trials
Buse, J. B., Garber, A., Rosenstock, J., Schmidt, W. E., Brett, J. H., Videbæk, N., Holst, Jens Juul & Nauck, M., 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 6, p. 1695-702 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucose-dependent insulinotropic polypeptide: a bifunctional glucose-dependent regulator of glucagon and insulin secretion in humans
Christensen, M., Vedtofte, L., Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2011, In: Diabetes. 60, 12, p. 3103-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lixisenatide for type 2 diabetes mellitus
Christensen, M., Knop, Filip Krag, Vilsbøll, Tina & Holst, Jens Juul, 2011, In: Expert Opinion on Investigational Drugs. 20, 4, p. 549-57 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Strenuous physical exercise adversely affects monocyte chemotaxis
Czepluch, F. S., Barrès, Romain, Caidahl, K., Olieslagers, S., Krook, A., Rickenlund, A., Zierath, Juleen R & Waltenberger, J., Jan 2011, In: Thrombosis and Haemostasis. 105, 1, p. 122-30 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adipose tissue fatty acid patterns and changes in anthropometry: a cohort study
Dahm, C. C., Gorst-Rasmussen, A., Jakobsen, M. U., Schmidt, E. B., Tjønneland, A., Sørensen, Thorkild I.A. & Overvad, K., 2011, In: P L o S One. 6, 7, p. e22587Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Treatments and services for neurodevelopmental disorders on advocacy websites: Information or evaluation?
Di Pietro, N. C., Whiteley, Louise & Illes, J., 2011, In: Neuroethics. 5, 2, p. 197-209 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nutrient-dependent acetylation controls basic regulatory metabolic switches and cellular reprogramming
Dominy, J. E., Gerhart-Hines, Zach & Puigserver, P., 2011, In: Cold Spring Harbor Symposia on Quantitative Biology. 76, p. 203-209 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Heritability of optic disc diameters: a twin study
Drobnjak, D., Taarnhøj, N. C., Mitchell, P., Wang, J. J., Tan, A., Kessel, Line, Hougaard, J., Sørensen, Thorkild I.A. & Larsen, Michael, 1 Mar 2011, In: Acta Ophthamologica (Online). 89, 2, p. e193-8Research output: Contribution to journal › Journal article › Research
- Published
Genetic polymorphisms in the hypothalamic pathway in relation to subsequent weight change--the DiOGenes study
Du, H., Ängquist, Lars, Vimaleswaran, K. S., Hansen, R. D., van der, D. L., Holst, C., Tjønneland, A., Overvad, K., Jakobsen, M. U., Boeing, H., Meidtner, K., Palli, D., Masala, G., Bouatia-Naji, N., Saris, W. H. M., Feskens, E. J. M., Wareham, N. J., Sørensen, Thorkild I.A. & Loos, R. J. F., 2011, In: P L o S One. 6, 2, p. e17436Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Improved glycemic control induced by both metformin and repaglinide is associated with a reduction in blood levels of 3-deoxyglucosone in nonobese patients with type 2 diabetes
Engelen, L., Lund, S. S., Ferreira, I., Tarnow, L., Parving, H., Gram, J., Winther, Kaj, Pedersen, Oluf Borbye, Teerlink, T., Barto, R., Stehouwer, C. D. A., Vaag, Allan & Schalkwijk, C. G., 2011, In: European Journal of Endocrinology. 164, 3, p. 371-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Changes in Glucose Homeostasis after Roux-en-Y Gastric Bypass Surgery for Obesity at Day Three, Two Months, and One Year after Surgery: Role of Gut Peptides
Falkén, Y., Hellström, P. M., Holst, Jens Juul & Näslund, E., 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 7, p. 2227-35 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A circadian rhythm orchestrated by histone deacetylase 3 controls hepatic lipid metabolism
Feng, D., Liu, T., Sun, Z., Bugge, A. S., Mullican, S. E., Alenghat, T., Liu, X. S. & Lazar, M. A., 11 Mar 2011, In: Science (New York, N.Y.). 331, 6022, p. 1315-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Is socioeconomic status of the rearing environment causally related to obesity in the offspring?
Fontaine, K. R., Robertson, H. T., Holst, C., Desmond, R., Stunkard, A. J., Sørensen, Thorkild I.A. & Allison, D. B., 2011, In: P L o S One. 6, 11, p. e27692Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Phosphorylation and Acetylation of Acyl-CoA Synthetase- I
Frahm, J. L., Li, L. O., Grevengoed, Trisha Jean & Coleman, R. A., 22 Jul 2011, In: Journal of Proteomics & Bioinformatics. 4, 7, p. 129-137 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic variation at CHRNA5-CHRNA3-CHRNB4 interacts with smoking status to influence body mass index
Freathy, R. M., Kazeem, G. R., Morris, R. W., Johnson, P. C. D., Paternoster, L., Ebrahim, S., Hattersley, A. T., Hill, A., Hingorani, A. D., Holst, C., Jefferis, B. J., Kring, S. I. I., Mooser, V., Padmanabhan, S., Preisig, M., Ring, S. M., Sattar, N., Upton, M. N., Vollenweider, P., Waeber, G. & 8 others, , 2011, In: International Journal of Epidemiology. 40, 6, p. 1617-28 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intrafamilial Variability of Early-Onset Diabetes due to an INS Mutation
Fredheim, S., Svensson, Jannet, Pørksen, S., Hansen, L., Hansen, Torben, Pedersen, Oluf Borbye, Mortensen, H. B., Barbetti, F. & Nielsen, L. B., 2011, In: Case Reports in Genetics. 2011, p. 258978Research output: Contribution to journal › Journal article › Research › peer-review
- Published
C-peptide increases Na,K-ATPase expression via PKC- and MAP kinase-dependent activation of transcription factor ZEB in human renal tubular cells
Galuska, D., Pirkmajer, S., Barrès, Romain, Ekberg, K., Wahren, J. & Chibalin, A. V., 2011, In: P L o S One. 6, 12, p. e28294Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In cirrhotic patients reduced muscle strength is unrelated to muscle capacity for ATP turnover suggesting a central limitation
Gam, C. M. B., Nielsen, H. B., Secher, Niels H., Larsen, F. S., Ott, P. & Quistorff, B., May 2011, In: Clinical Physiology and Functional Imaging. 31, 3, p. 169-74 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neuroethics and fMRI: Mapping a fledgling relationship
Garnett, A., Whiteley, Louise, Piwowar, H., Rasmussen, E. & Illes, J., 22 Apr 2011, In: P L o S One. 6, 4, p. e18537Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The cAMP/PKA Pathway Rapidly Activates SIRT1 to Promote Fatty Acid Oxidation Independently of Changes in NAD +
Gerhart-Hines, Zach, Dominy, J. E., Blättler, S. M., Jedrychowski, M. P., Banks, A. S., Lim, J. H., Chim, H., Gygi, S. P. & Puigserver, P., 23 Dec 2011, In: Molecular Cell. 44, 6, p. 851-863 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Carriers of the TCF7L2 rs7903146 TT genotype have elevated levels of plasma glucose, serum proinsulin and plasma gastric inhibitory polypeptide (GIP) during a meal test
Gjesing, A. P., Kjems, L. L., Vestmar, M. A., Grarup, Niels, Linneberg, Allan René, Deacon, Carolyn F., Holst, Jens Juul, Pedersen, Oluf Borbye & Hansen, Torben, 1 Jan 2011, In: Diabetologia. 54, 1, p. 103-10 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Studies of a genetic variant in HK1 in relation to quantitative metabolic traits and to the prevalence of type 2 diabetes
Gjesing, A. P., Nielsen, A. A., Brandslund, I., Christensen, C., Sandbæk, A., Jørgensen, T., Witte, D., Bonnefond, A., Froguel, P., Hansen, Torben & Pedersen, Oluf Borbye, 1 Jan 2011, In: B M C Medical Genetics. 12, p. 99 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The Effect of PCSK1 Variants on Waist, Waist-Hip Ratio and Glucose Metabolism Is Modified by Sex and Glucose Tolerance Status
Gjesing, A. P., Vestmar, M. A., Jørgensen, T., Heni, M., Holst, Jens Juul, Witte, D. R., Hansen, Torben & Pedersen, Oluf Borbye, 1 Jan 2011, In: P L o S One. 6, 9, p. e23907 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Familial mild hyperglycemia associated with a novel ABCC8-V84I mutation within three generations
Gonsorcikova, L., Vaxillaire, M., Pruhova, S., Dechaume, A., Dusatkova, P., Cinek, O., Pedersen, Oluf Borbye, Froguel, P., Hansen, Torben & Lebl, J., 1 May 2011, In: Pediatric Diabetes. 12, 3pt2, p. 266-9 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GHR knockout and the CNS
Gosney, E. S. & Kopchick, J. J., 1 Dec 2011, Laron Syndrome - From Man to Mouse: Lessons from Clinical and Experimental Experience. Springer Berlin/Heidelberg, p. 489-493 5 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
The diabetogenic VPS13C/C2CD4A/C2CD4B rs7172432 variant impairs glucose-stimulated insulin response in 5,722 non-diabetic Danish individuals
Grarup, Niels, Overvad, M., Sparsø, T., Witte, D. R., Pisinger, C., Jørgensen, T., Yamauchi, T., Hara, K., Maeda, S., Kadowaki, T., Hansen, T. & Pedersen, Oluf Borbye, 2011, In: Diabetologica. 54, 4, p. 789-94 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human papillomavirus 16 E5 modulates the expression of host microRNAs
Greco, D., Kivi, N., Qian, K., Leivonen, S., Auvinen, P. & Auvinen, E., 2011, In: PloS one. 6, 7, p. e21646Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Delayed onset of hyperglycaemia in a mouse model with impaired glucagon secretion demonstrates that dysregulated glucagon secretion promotes hyperglycaemia and type 2 diabetes
Gustavsson, N., Seah, T., Lao, Y., Radda, G. K., Südhof, T. C. & Han, W., Feb 2011, In: Diabetologia. 54, 2, p. 415-22 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synaptotagmin-7 as a positive regulator of glucose-induced glucagon-like peptide-1 secretion in mice
Gustavsson, N., Wang, Y., Kang, Y., Seah, T., Chua, S., Radda, G. K. & Han, W., Jul 2011, In: Diabetologia. 54, 7, p. 1824-30 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of method of delivery of sodium butyrate on rumen development in newborn calves
Górka, P., Kowalski, Z. M., Pietrzak, P., Kotunia, A., Jagusiak, W., Holst, Jens Juul, Guilloteau, P. & Zabielski, R., Nov 2011, In: Journal of Dairy Science. 94, 11, p. 5578-88 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intake of total, animal and plant protein and subsequent changes in weight or waist circumference in European men and women: the Diogenes project
Halkjær, J., Olsen, A., Overvad, K., Jakobsen, M. U., Boeing, H., Buijsse, B., Palli, D., Tognon, G., Du, H., van der, D. L., Forouhi, N. G., Wareham, N. J., Feskens, E. J. M., Sørensen, Thorkild I.A. & Tjønneland, A., 2011, In: International Journal of Obesity. 35, 8, p. 1104-13 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Upregulation of alpha cell glucagon-like peptide 1 (GLP-1) in Psammomys obesus--an adaptive response to hyperglycaemia?
Hansen, A. M. K., Bödvarsdottir, T. B., Nordestgaard, D. N. E., Heller, Rasmus, Gotfredsen, C. F., Maedler, K., Fels, J., Holst, Jens Juul & Karlsen, A., 2011, In: Diabetologia. 54, 6, p. 1379-87 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2-Oleoyl glycerol is a GPR119 agonist and signals GLP-1 release in humans
Hansen, K. B., Rosenkilde, Mette, Knop, Filip Krag, Wellner, N., Diep, T. A., Rehfeld, Jens Frederik, Andersen, U. B., Holst, Jens Juul & Hansen, Harald S., 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 9, p. E1409-17Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased Postprandial GIP and Glucagon Responses, But Unaltered GLP-1 Response after Intervention with Steroid Hormone, Relative Physical Inactivity, And High-Calorie Diet in Healthy Subjects
Hansen, K. B., Vilsbøll, Tina, Bagger, J. I., Holst, Jens Juul & Knop, Filip Krag, 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 2, p. 447-53 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition de la sécrétion du glucagon par les antagonistes du GLP-1 et les inhibiteurs de la DPP-4
Hansen, M., Knop, Filip Krag & Holst, Jens Juul, Apr 2011, In: Medecine des Maladies Metaboliques. 5, 2Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of glucagon secretion by GLP-1 agonists and DPP4 inhibitors
Hansen, M., Juul Hare, K., Holst, Jens Juul & Knop, Filip Krag, Jun 2011, In: Journal of Clinical Metabolism & Diabetes. 2, 2, p. 7-13 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Corrigendum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution
Heid, I. M., Jackson, A. U., Randall, J. C., Winkler, T. W., Qi, L., Steinthorsdottir, V., Thorleifsson, G., Zillikens, M. C., Speliotes, E. K., Mägi, R., Workalemahu, T., White, C. C., Bouatia-Naji, N., Harris, T. B., Berndt, S. I., Ingelsson, E., Willer, C. J., Weedon, M. N., Luan, J., Vedantam, S. & 280 others, , 1 Jan 2011, In: Nature Genetics. 43, 11, p. 1164 1 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Effects of saxagliptin on β-cell stimulation and insulin secretion in patients with type 2 diabetes
Henry, R. R., Smith, S., Schwartz, S., Mudaliar, S. R., Deacon, Carolyn F., Holst, Jens Juul, Duan, R. Y., Chen, R. S. & List, J. F., 2011, In: Diabetes, Obesity and Metabolism. 13, 9, p. 850-858 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Delayed ß-cell response and glucose intolerance in young women with Turner syndrome
Hjerrild, B. E., Holst, Jens Juul, Juhl, C., Christiansen, J. S., Schmitz, O. & Gravholt, C. H., 2011, In: B M C Endocrine Disorders. 11, p. 11-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dipeptidyl peptidase-4 inhibition increases portal concentrations of intact glucagon-like peptide-1 (GLP-1) to a greater extent than peripheral concentrations in anaesthetised pigs
Hjøllund, K. R., Deacon, Carolyn F. & Holst, Jens Juul, 2011, In: Diabetologia. 54, 8, p. 2206-8 3 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Chronic care treatment of obese children and adolescents
Holm, Jens-Christian, Gamborg, M., Bille, D. S., Gr Nb K, H. N., Ward, L. C. & Faerk, J., Aug 2011, In: International journal of pediatric obesity : IJPO : an official journal of the International Association for the Study of Obesity. 6, 3-4, p. 188-96 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tracking of leptin, soluble leptin receptor, and the free leptin index during weight loss and regain in children
Holm, J., Gamborg, M., Ward, L. C., Gammeltoft, S., Kaas-Ibsen, K., Heitmann, B. L. & Sørensen, Thorkild I.A., 2011, In: Obesity Facts. 4, 6, p. 461-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Loss of Incretin Effect Is a Specific, Important, and Early Characteristic of Type 2 Diabetes
Holst, Jens Juul, Knop, Filip Krag, Vilsbøll, Tina, Krarup, T. & Madsbad, Sten, May 2011, In: Diabetes Care. 34, Supplement 2, p. S251-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neuroprotective properties of GLP-1: theoretical and practical applications
Holst, Jens Juul, Burcelin, R. & Nathanson, E., 2011, In: Current Medical Research and Opinion. 27, 3, p. 547-58 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Postprandial insulin secretion after gastric bypass surgery: the role of glucagon-like peptide 1
Holst, Jens Juul, Sep 2011, In: Diabetes. 60, 9, p. 2203-2205 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulation of glucagon secretion by incretins
Holst, Jens Juul, Christensen, M., Lund, A., de Heer, J., Svendsen, B., Kielgast, U. & Knop, Filip Krag, Oct 2011, In: Diabetes, Obesity and Metabolism. 13 , Suppl 1, p. 89-94 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association between CST3 rs2424577 polymorphism and corpulence related phenotypes during lifetime in populations of European ancestry
Hooton, H., Dubern, B., Henegar, C., Paternoster, L., Nohr, E. A., Alili, R., Rousseau, F., Pelloux, V., Galan, P., Hercberg, S., Arner, P., Sørensen, Thorkild I.A. & Clément, K., 2011, In: Obesity Facts. 4, 2, p. 131-44 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The minor C-allele of rs2014355 in ACADS is associated with reduced insulin release following an oral glucose load
Hornbak, M., Banasik, Karina, Justesen, Johanne Marie, Krarup, N. T., Sandholt, C. H., Andersson, Åsa, Sandbaek, A., Lauritzen, T., Pisinger, C., Witte, D. R., Sørensen, Thorkild I.A., Pedersen, Oluf Borbye & Hansen, Torben, 6 Jan 2011, In: BMC Medical Genetics. 12, 1, p. 4 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucose tolerance, insulin sensitivity and insulin release in European non-diabetic carriers of a polymorphism upstream of CDKN2A and CDKN2B
Hribal, M. L., Presta, I., Procopio, T., Marini, M. A., Stancáková, A., Kuusisto, J., Andreozzi, F., Hammarstedt, A., Jansson, P., Grarup, Niels, Hansen, Torben, Walker, M., Stefan, N., Fritsche, A., Häring, H. U., Pedersen, Oluf Borbye, Smith, U., Laakso, M., Sesti, G. & EUGENE2 Consortium, E. C., 2011, In: Diabetologia. 54, 4, p. 795-802 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A role for coding functional variants in HNF4A in type 2 diabetes susceptibility
Jafar-Mohammadi, B., Groves, C. J., Gjesing, A. P., Herrera, B. M., Winckler, W., Stringham, H. M., Morris, A. P., Lauritzen, T., Doney, A. S. F., Morris, A. D., Weedon, M. N., Swift, A. J., Kuusisto, J., Laakso, M., Altshuler, D., Hattersley, A. T., Collins, F. S., Boehnke, M., Hansen, T., Pedersen, O. & 5 others, , Jan 2011, In: Diabetologia. 54, 1, p. 111-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma phospholipid long-chain n-3 polyunsaturated fatty acids and body weight change
Jakobsen, M. U., Dethlefsen, C., Due, K. M., Slimani, N., Chajès, V., May, A. M., Sørensen, T. I. A., Halkjær, J., Tjønneland, A., Clavel-Chapelon, F., Boutron-Ruault, M-C., Fagherazzi, G., Teucher, B., Kaaks, R., Boeing, H., Schütze, M., Trichopoulou, A., Zylis, D., Makrygiannis, G., Palli, D. & 21 others, , 2011, In: Obesity Facts. 4, 4, p. 312-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
FoxO3A promotes metabolic adaptation to hypoxia by antagonizing Myc function
Jensen, K. S., Binderup, Tina, Jensen, K. T., Therkelsen, I., Borup, R., Nilsson, E., Multhaupt, Hinke Arnolda B V H, Bouchard, C., Quistorff, B., Kjær, Andreas, Landberg, G. & Staller, P., 16 Nov 2011, In: E M B O Journal. 30, 22, p. 4554-70 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Foetal proglucagon processing in relation to adult appetite control: lessons from a transplantable rat glucagonoma with severe anorexia
Jensen, P. B., Larsen, P. J., Karlsen, C., Jensen, H. I., Holst, Jens Juul & Madsen, O. D., Oct 2011, In: Diabetes, Obesity and Metabolism. 13 , Suppl. 1, p. 60-68 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome wide association study identifies KCNMA1 contributing to human obesity
Jiao, H., Arner, P., Hoffstedt, J., Brodin, D., Dubern, B., Czernichow, S., van't Hooft, F., Axelsson, T., Pedersen, Oluf Borbye, Hansen, Torben, Sørensen, Thorkild I.A., Hebebrand, J., Kere, J., Dahlman-Wright, K., Hamsten, A., Clement, K. & Dahlman, I., 2011, In: B M C Medical Genomics. 4, p. 51 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity
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Determinants of plasma levels of proglucagon and the metabolic impact of glucagon receptor signalling: a UK Biobank study
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Targeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment
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mTORC1 controls murine postprandial hepatic glycogen synthesis via Ppp1r3b
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