- 2008
- Published
The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm
Helgadottir, A., Thorleifsson, G., Magnusson, K. P., Grétarsdottir, S., Steinthorsdottir, V., Manolescu, A., Jones, G. T., Rinkel, G. J. E., Blankensteijn, J. D., Ronkainen, A., Jääskeläinen, J. E., Kyo, Y., Lenk, G. M., Sakalihasan, N., Kostulas, K., Gottsäter, A., Flex, A., Stefansson, H., Hansen, T., Andersen, G. & 48 others, , 2008, In: Nature Genetics. 40, 2, p. 217-24 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Polymorphisms in AHI1 are not associated with type 2 diabetes or related phenotypes in Danes: non-replication of a genome-wide association result
Holmkvist, J., Anthonsen, S., Wegner, L., Andersen, G., Jørgensen, T., Borch-Johnsen, K., Sandbaek, A., Lauritzen, T., Pedersen, Oluf Borbye & Hansen, Torben, 2008, In: Diabetologia. 51, 4, p. 609-14 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact on weight dynamics and general growth of the common FTO rs9939609: a longitudinal Danish cohort study
Jess, T., Zimmermann, E., Kring, S. I. I., Berentzen, T., Holst, C., Toubro, S., Astrup, A., Hansen, Torben, Pedersen, O., Sørensen, Thorkild I.A. & Pedersen, Oluf Borbye, 2008, In: International Journal of Obesity. 32, 9, p. 1388-94 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The PPAR gamma 2 Pro12Ala variant predicts ESRD and mortality in patients with type 1 diabetes and diabetic nephropathy
Jorsal, A., Tarnow, L., Lajer, M., Ek, J., Hansen, Torben, Pedersen, Oluf Borbye & Parving, H., 2008, In: Molecular Genetics and Metabolism. 94, 3, p. 347-51 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Physical exercise during pregnancy and the risk of preterm birth: A study within the danish national birth cohort
Juhl, M., Andersen, Per Kragh, Olsen, J., Madsen, M., Jørgensen, Tina, Nøhr, E. A. & Nybo Andersen, Anne-Marie, Aug 2008, In: Obstetrical and Gynecological Survey. 63, 8, p. 495-497 3 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
FTO gene associated fatness in relation to body fat distribution and metabolic traits throughout a broad range of fatness
Kring, S. I. I., Holst, C., Zimmermann, E., Jess, T., Berentzen, T., Toubro, S., Hansen, Torben, Astrup, A., Pedersen, Oluf Borbye & Sørensen, Thorkild I.A., 2008, In: PLoS ONE. 3, 8, p. e2958 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genotype-phenotype associations in obesity dependent on definition of the obesity phenotype
Kring, S. I. I., Larsen, L. H., Holst, C., Toubro, S., Hansen, Torben, Astrup, A., Pedersen, Oluf Borbye & Sørensen, Thorkild I.A., 2008, In: Obesity Facts. 1, 3, p. 138-145 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Receptorji s sedmimi transmembranskimi območji (7TM) v luči dimerizacije ter eksperimentalni pristopi za proučevanje njihove dimerizacije in medsebojnih vplivov
Kubale, V., Pogačnik, A., Schwartz, Thue W. & Vrecl, M., 2008, In: Slovenian Veterinary Research. 45, 3, p. 89-102 14 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Insulin sensitivity, insulin release and glucagon-like peptide-1 levels in persons with impaired fasting glucose and/or impaired glucose tolerance in the EUGENE2 study
Laakso, M., Zilinskaite, J., Hansen, Torben, Boesgaard, T. W., Vänttinen, M., Stancáková, A., Jansson, P., Pellmé, F., Kuulasmaa, T., Hribal, M. L., Sesti, G., Stefan, N., Fritsche, A., Häring, H., Pedersen, Oluf Borbye, Smith, U., EUGENE2 Consortium, E. C. & Holst, Jens Juul, 2008, In: Diabetologia. 51, 3, p. 502-11 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The use of proteomics to study infectious diseases
List, E. O., Berryman, D. E., Bower, B., Sackmann-Sala, L., Gosney, E., Ding, J., Okada, S. & Kopchick, J. J., 1 Mar 2008, In: Infectious Disorders - Drug Targets. 8, 1, p. 31-45 15 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Impact of metformin versus repaglinide on non-glycaemic cardiovascular risk markers related to inflammation and endothelial dysfunction in non-obese patients with type 2 diabetes
Lund, S. S., Tarnow, L., Stehouwer, C. D. A., Schalkwijk, C. G., Teerlink, T., Gram, J., Winther, K., Frandsen, M., Smidt, U. M., Pedersen, Oluf Borbye, Parving, H. & Vaag, Allan, 2008, In: European Journal of Endocrinology. 158, 5, p. 631-41 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of metformin versus the prandial insulin secretagogue, repaglinide, on fasting and postprandial glucose and lipid responses in non-obese patients with type 2 diabetes
Lund, S. S., Tarnow, L., Frandsen, M., Smidt, U. M., Pedersen, Oluf Borbye, Parving, H. & Vaag, Allan, 2008, In: European Journal of Endocrinology. 158, 1, p. 35-46 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Clinical risk factors, DNA variants, and the development of type 2 diabetes
Lyssenko, V., Jonsson, Anna Elisabet, Almgren, P., Pulizzi, N., Isomaa, B., Tuomi, T., Berglund, G., Altshuler, D., Nilsson, P. & Groop, L., 20 Nov 2008, In: New England Journal of Medicine. 359, 21, p. 2220-32 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oxidative stress in primary glomerular diseases: a comparative study
Markan, S., Kohli, H. S., Sud, K., Ahuja, M., Ahluwalia, Tarun Veer Singh, Sakhuja, V. & Khullar, M., Apr 2008, In: Molecular and Cellular Biochemistry. 311, 1-2, p. 105-10 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The KCNMB1 Glu65Lys polymorphism associates with reduced systolic and diastolic blood pressure in the Inter99 study of 5729 Danes.
Nielsen, T., Burgdorf, K. S., Grarup, Niels, Borch-Johnsen, K., Hansen, T., Jørgensen, T., Pedersen, Oluf Borbye & Andersen, G., 2008, In: Journal of Hypertension. 26, 11, p. 2142-6 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic and environmental effects on mortality before age 70 years
Petersen, L., Andersen, Per Kragh, Sørensen, Thorkild I.A., Petersen, L., Andersen, P. K. & Sørensen, Thorkild I.A., 1 May 2008, In: Epidemiology. 19, 3, p. 472-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ACE I/D polymorphism in Indian patients with hypertrophic cardiomyopathy and dilated cardiomyopathy
Rai, T. S., Dhandapany, P. S., Ahluwalia, Tarun Veer Singh, Bhardwaj, M., Bahl, A., Talwar, K. K., Nair, K., Rathinavel, A. & Khullar, M., Apr 2008, In: Molecular and Cellular Biochemistry. 311, 1-2, p. 67-72 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabolic adaptations through the PGC-1α and SIRT1 pathways
Rodgers, J. T., Lerin, C., Gerhart-Hines, Zach & Puigserver, P., 9 Jan 2008, In: FEBS Letters. 582, 1, p. 46-53 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Non-replication of genome-wide based associations between common variants in INSIG2 and PFKP and obesity in studies of 18,014 Danes
Sandholt, C. H., Mogensen, M. S., Borch-Johnsen, K., Sandbaek, A., Lauritzen, T., Sørensen, Thorkild I.A., Hansen, L., Almind, K., Jørgensen, T., Pedersen, Oluf Borbye & Hansen, Torben, 2008, In: PLoS ONE. 3, 8, p. e2872 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The search for putative unifying genetic factors for components of the metabolic syndrome
Sjögren, M., Lyssenko, V., Jonsson, Anna Elisabet, Berglund, G., Nilsson, P., Groop, L. & Orho-Melander, M., Dec 2008, In: Diabetologia. 51, 12, p. 2242-51 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of polymorphisms in WFS1 on prediabetic phenotypes in a population-based sample of middle-aged people with normal and abnormal glucose regulation
Sparsø, T., Andersen, G., Albrechtsen, Anders, Jørgensen, T., Borch-Johnsen, K., Sandbaek, A., Lauritzen, T., Wasson, J., Permutt, M. A., Glaser, B., Madsbad, Sten, Pedersen, Oluf Borbye & Hansen, Torben, 2008, In: Diabetologia. 51, 9, p. 1646-52 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A candidate type 2 diabetes polymorphism near the HHEX locus affects acute glucose-stimulated insulin release in European populations: results from the EUGENE2 study
Staiger, H., Stancáková, A., Zilinskaite, J., Vänttinen, M., Hansen, T., Marini, M. A., Hammarstedt, A., Jansson, P., Sesti, G., Smith, U., Pedersen, Oluf Borbye, Laakso, M., Stefan, N., Fritsche, A. & Häring, H., 2008, In: Diabetes. 57, 2, p. 514-7 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Single-nucleotide polymorphism rs7754840 of CDKAL1 is associated with impaired insulin secretion in nondiabetic offspring of type 2 diabetic subjects and in a large sample of men with normal glucose tolerance
Stancáková, A., Pihlajamäki, J., Kuusisto, J., Stefan, N., Fritsche, A., Häring, H., Andreozzi, F., Succurro, E., Sesti, G., Boesgaard, T. W., Hansen, T., Pedersen, Oluf Borbye, Jansson, P. A., Hammarstedt, A., Smith, U., Laakso, M. & EUGENE2 Consortium, E. C., 2008, In: Journal of Clinical Endocrinology and Metabolism. 93, 5, p. 1924-30 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Possible role of AS160 in post-exercise increased insulin sensitivity in human skeletal muscle
Treebak, Jonas Thue, Kristensen, Jonas Møller, Frosig, C., Pehmoller, C., Hardie, D. G., Kiens, Bente, Richter, Erik A. & Wojtaszewski, Jørgen F P, 2008, In: Diabetes.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations.
Unoki, H., Takahashi, A., Kawaguchi, T., Hara, K., Horikoshi, M., Andersen, G., Ng, D. P. K., Holmkvist, J., Borch-Johnsen, K., Jørgensen, T., Sandbæk, A., Lauritzen, T., Hansen, T., Nurbaya, S., Tsunoda, T., Kubo, M., Babazono, T., Hirose, H., Hayashi, M., Iwamoto, Y. & 10 others, , 2008, In: Nature Genetics. 40, 9, p. 1098-1102 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Gly482Ser genotype at the PPARGC1A gene and elevated blood pressure: a meta-analysis involving 13,949 individuals
Vimaleswaran, K. S., Luan, J., Andersen, G., Muller, Y. L., Wheeler, E., Brito, E. C., O'Rahilly, S., Pedersen, Oluf Borbye, Baier, L. J., Knowler, W. C., Barroso, I., Wareham, N. J., Loos, R. J. F. & Franks, P. W., 2008, In: Journal of Applied Physiology. 105, 4, p. 1352-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of TCF7L2 rs7903146 on insulin secretion and action in young and elderly Danish twins.
Wegner, L., Hussain, M. S., Pilgaard, K., Hansen, T., Pedersen, Oluf Borbye, Vaag, Allan & Poulsen, I. P., 2008, In: Journal of Clinical Endocrinology and Metabolism. 93, 10, p. 4013-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Implicit knowledge of visual uncertainty guides decisions with asymmetric outcomes
Whiteley, Louise & Sahani, M., 2008, In: Journal of Vision. 8, 3, p. 2.1-15Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Uncertainty, reward, and attention in the Bayesian brain
Whiteley, Louise, 2008Research output: Book/Report › Ph.D. thesis
- Published
Visual processing and the bodily self
Whiteley, Louise, Spence, C. & Haggard, P., 2008, In: Acta Psychologica. 127, 1, p. 129-36 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus
Yasuda, K., Miyake, K., Horikawa, Y., Hara, K., Osawa, H., Furuta, H., Hirota, Y., Mori, H., Jonsson, A. E., Sato, Y., Yamagata, K., Hinokio, Y., Wang, H-Y., Tanahashi, T., Nakamura, N., Oka, Y., Iwasaki, N., Iwamoto, Y., Yamada, Y., Seino, Y. & 27 others, , Sep 2008, In: Nature Genetics. 40, 9, p. 1092-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes
Zeggini, E., Scott, L. J., Saxena, R., Voight, B. F., Marchini, J. L., Hu, T., de Bakker, P. I. W., Abecasis, G. R., Almgren, P., Andersen, G., Ardlie, K., Boström, K. B., Bergman, R. N., Bonnycastle, L. L., Borch-Johnsen, K., Burtt, N. P., Chen, H., Chines, P. S., Daly, M. J., Deodhar, P. & 31 others, , 2008, In: Nature Genetics. 40, 5, p. 638-45 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Somewhat Subjective Introduction to Gene Mapping through Nonparametric Linkage Analysis
Ängquist, Lars, 2008, Genetic Recombination Research Progress. Schultz, J. H. (ed.). Nova Biomedical Books, 60 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
A Unified Discussion on the Concept of Score Functions Used in the Context of Nonparametric Linkage Analysis
Ängquist, Lars, 2008, In: Bioinformatics and Biology Insights. 2, p. 119-132 PMID:19812770.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Strategies for conditional two-locus nonparametric linkage analysis
Ängquist, Lars, Hössjer, O. & Groop, L., 1 Jul 2008, In: Human Heredity. 66, 3, p. 138-156 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effects of soy isoflavones on obesity
Ørgaard, A. & Jensen, L., 5 Jun 2008, In: Experimental Biology and Medicine (Maywood). 233, 9, p. 1066-80 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2007
- Published
Concentrations of the acute phase reactants high-sensitive C-reactive protein and YKL-40 and of interleukin-6 before and after treatment in patients with acromegaly and growth hormone deficiency
Andreassen, Mikkel, drb459, drb459 & Kristensen, L. Ø., Dec 2007, In: Clinical Endocrinology. 67, 6, p. 909-16 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Discovery and uses of pegvisomant: A growth hormone antagonist
Berryman, D. E., Palmer, A. J., Gosney, E. S., Swaminathan, S., DeSantis, D. & Kopchick, J. J., 1 Dec 2007, In: Endokrynologia Polska. 58, 4, p. 322-329 8 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Glucagon-like peptide-2 in umbilical cord blood from mature infants
Bodé, S., Hartmann, Bolette, Holst, Jens Juul & Greisen, Gorm, 2007, In: Neonatology. 91, 1, p. 49-53 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A common haplotype in the G-protein-coupled receptor gene GPR74 is associated with leanness and increased lipolysis
Dahlman, I., Dicker, A., Jiao, H., Kere, J., Blomqvist, L., van Harmelen, V., Hoffstedt, J., Borch-Johnsen, K., Jorgensen, T., Hansen, Torben, Pedersen, Oluf Borbye, Laakso, M. & Arner, P., 2007, In: American Journal of Human Genetics. 80, 6, p. 1115-24 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rosiglitazone monotherapy for type 2 diabetes mellitus-too soon to ADOPT?
Gaede, P. & Pedersen, Oluf Borbye, 2007, In: Nature clinical practice. Endocrinology & metabolism. 3, 6, p. 456-7 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1α
Gerhart-Hines, Zach, Rodgers, J. T., Bare, O., Lerin, C., Kim, S. H., Mostoslavsky, R., Alt, F. W., Wu, Z. & Puigserver, P., 4 Apr 2007, In: EMBO Journal. 26, 7, p. 1913-1923 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies of the associations between functional beta2-adrenergic receptor variants and obesity, hypertension and type 2 diabetes in 7,808 white subjects
Gjesing, A. P., Andersen, G., Burgdorf, Kristoffer Sølvsten, Borch-Johnsen, K., Jørgensen, T., Hansen, Torben & Pedersen, Oluf Borbye, Mar 2007, In: Diabetologia. 50, 3, p. 563-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Porcine transcriptome analysis based on 97 non-normalized cDNA libraries and assembly of 1,021,891 expressed sequence tags
Gorodkin, J., Cirera, S., Hedegaard, J., Gilchrist, M. J., Panitz, F., Jørgensen, C., Scheibye-Knudsen, K., Arvin, T., Lumholdt, S., Sawera, M., Green, T., Nielsen, B., Havgaard, J. H., Rosenkilde, C., Wang, J., Li, H., Li, R., Liu, B., Hu, S., Dong, W. & 16 others, , 2007, In: Genome Biology. 8, R45, p. R45 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies of the common DIO2 Thr92Ala polymorphism and metabolic phenotypes in 7342 Danish white subjects
Grarup, Niels, Lepola, Mette Andersen, Andreasen, C. H., Albrechtsen, Anders, Borch-Johnsen, K., Jørgensen, T., Auwerx, J., Schmitz, O., Hansen, Torben & Pedersen, Oluf Borbye, 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 1, p. 363-6 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes
Gudmundsson, J., Sulem, P., Steinthorsdottir, V., Bergthorsson, J. T., Thorleifsson, G., Manolescu, A., Rafnar, T., Gudbjartsson, D., Agnarsson, B. A., Baker, A., Sigurdsson, A., Benediktsdottir, K. R., Jakobsdottir, M., Blondal, T., Stacey, S. N., Helgason, A., Gunnarsdottir, S., Olafsdottir, A., Kristinsson, K. T., Birgisdottir, B. & 55 others, , 2007, In: Nature Genetics. 39, 8, p. 977-983 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The BIGTT test: a novel test for simultaneous measurement of pancreatic beta-cell function, insulin sensitivity, and glucose tolerance
Hansen, Torben, Drivsholm, Thomas, Urhammer, S. A., Palacios, R. T., Vølund, A., Borch-Johnsen, K. & Pedersen, Oluf Borbye, 2007, In: Diabetes Care. 30, 2, p. 257-262 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution
Helgason, A., Pálsson, S., Thorleifsson, G., Grant, S. F. A., Emilsson, V., Gunnarsdottir, S., Adeyemo, A., Chen, Y., Chen, G., Reynisdottir, I., Benediktsson, R., Hinney, A., Hansen, T., Andersen, G., Borch-Johnsen, K., Jorgensen, T., Schäfer, H., Faruque, M., Doumatey, A., Zhou, J. & 13 others, , 2007, In: Nature Genetics. 39, 2, p. 218-25 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Disassociation of bone resorption and formation by GLP-2: a 14-day study in healthy postmenopausal women
Henriksen, D. B., Alexandersen, P., Hartmann, Bolette, Adrian, C. L., Byrjalsen, I., Bone, H. G., Holst, Jens Juul & Christiansen, C., Mar 2007, In: Bone. 40, 3, p. 723-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hyperphosphorylation and low protein content of muscle glycogen synthase contribute to insulin resistance in polycystic ovary syndrome: effects of pioglitazone treatment
Hojlund, K., Glintborg, D., Andersen, N. R., Birk, Jesper Bratz, Treebak, Jonas Thue, Beck-Nielsen, H. & Wojtaszewski, Jørgen F P, 2007, In: Diabetologia.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bone resorption is decreased postprandially by intestinal factors and glucagon-like peptide-2 is a possible candidate
Holst, Jens Juul, Hartmann, Bolette, Gottschalck, I. B., Jeppesen, Palle Bekker, Miholic, J. & Henriksen, D. B., Jul 2007, In: Scandinavian Journal of Gastroenterology. 42, 7, p. 814-20 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The “mesh” as evidence – model comparison and alternative interpretations of feedback
Hulme, Oliver James & Whiteley, Louise, 2007, In: Behavioral and Brain Sciences. 30Research output: Contribution to journal › Comment/debate › Communication
- Published
The functional Pro129Thr variant of the FAAH gene is not associated with various fat accumulation phenotypes in a population-based cohort of 5,801 whites
Jensen, D. P., Lepola, Mette Andersen, Hansen, L., Eiberg, Hans Rudolf Lytchoff, Borch-Johnsen, K., Jørgensen, T., Hansen, Torben, Pedersen, Oluf Borbye & Andreasen, C. H., 2007, In: Journal of Molecular Medicine. 85, 5, p. 445-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Polymorphisms in the 3' UTR in the neurocalcin delta gene affect mRNA stability, and confer susceptibility to diabetic nephropathy
Kamiyama, M., Kobayashi, M., Araki, S., Iida, A., Tsunoda, T., Kawai, K., Imanishi, M., Nomura, M., Babazono, T., Iwamoto, Y., Kashiwagi, A., Kaku, K., Kawamori, R., Ng, D. P. K., Hansen, Torben, Gaede, P., Pedersen, Oluf Borbye, Nakamura, Y. & Maeda, S., 2007, In: Human Genetics. 122, 3-4, p. 397-407 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Treeterbi and Parallel Treeterbi algorithms: efficient, optimal decoding for ordinary, generalized and pair HMMs.
Keibler, E., Arumugam, Mani & Brent, M. R., Mar 2007, In: Bioinformatics. 23, 5, p. 545-554 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic analysis of the estrogen-related receptor alpha and studies of association with obesity and type 2 diabetes
Larsen, L. H., Rose, C. S., Sparsø, T., Overgaard, J., Torekov, Signe Sørensen, Grarup, Niels, Jensen, Dan Funck, Albrechtsen, Anders, Andersen, G., Ek, J., Glümer, C., Borch-Johnsen, K., Jørgensen, Tina, Hansen, Teis Schjals & Pedersen, Oluf Borbye, 2007, In: International Journal of Obesity. 31, 2, p. 365-70 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Porcine glucagon-like peptide-2: structure, signaling, metabolism and effects
Pedersen, N. B., Hjøllund, K. R., Johnsen, A. H., Ørskov, Cathrine, Rosenkilde, Mette, Hartmann, B. & Holst, Jens Juul, 2007, In: Regulatory Peptides. 146, 1-3, p. 310-320 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The human PINK1 locus is regulated in vivo by a non-coding natural antisense RNA during modulation of mitochondrial function
Schéele, Camilla Charlotte Nielsen, Petrovic, N., Faghihi, M. A., Lassmann, T., Fredriksson, K., Rooyackers, O., Wahlestedt, C., Good, L. & Timmons, J. A., 15 Mar 2007, In: BMC Genomics. 8, p. 74Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes
Sparsø, T., Andersen, G., Nielsen, T., Burgdorf, K. S., Gjesing, A. M. P., Nielsen, A. L., Albrechtsen, Anders, Rasmussen, S. S., Jørgensen, T., Borch-Johnsen, K., Sandbaek, A., Lauritzen, T., Madsbad, Sten, Hansen, Torben & Pedersen, Oluf Borbye, 2007, In: Diabetologia. 51, 1, p. 70-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Relationships between the functional PPARalpha Leu162Val polymorphism and obesity, type 2 diabetes, dyslipidaemia, and related quantitative traits in studies of 5799 middle-aged white people
Sparsø, T., Hussain, M. S., Andersen, G., Hainerova, I., Borch-Johnsen, K., Jørgensen, T., Hansen, Torben & Pedersen, Oluf Borbye, 2007, In: Molecular Genetics and Metabolism. 90, 2, p. 205-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies of association of the CASQ1 rs2275703 polymorphism in relation to type 2 diabetes and related quantitative metabolic traits among 7,088 Danish whites
Sparsø, T., Hussain, M. S., Borch-Johnsen, K., Jørgensen, T., Madsbad, Sten, Hansen, Torben, Pedersen, Oluf Borbye & Andersen, G., 2007, In: Molecular Genetics and Metabolism. 92, 3, p. 278-282 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A variant in CDKAL1 influences insulin response and risk of type 2 diabetes
Steinthorsdottir, V., Thorleifsson, G., Reynisdottir, I., Benediktsson, R., Jonsdottir, T., Walters, G. B., Styrkarsdottir, U., Gretarsdottir, S., Emilsson, V., Ghosh, S., Baker, A., Snorradottir, S., Bjarnason, H., Ng, M. C. Y., Hansen, T., Bagger, Y., Wilensky, R. L., Reilly, M. P., Adeyemo, A., Chen, Y. & 25 others, , 2007, In: Nature Genetics. 39, 6, p. 770-5 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association between obesity and asthma in a twin cohort
Thomsen, S., Ulrik, Charlotte Suppli, Kyvik, K., Sørensen, Thorkild I.A., Posthuma, D., Skadhauge, L., Steffensen, I. & Backer, V., 2007, In: Allergy. European Journal of Allergy and Clinical Immunology. 62, 10, p. 1199-1204 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
AS160 phosphorylation is associated with activation of alpha(2)beta(2)gamma(1)- but not alpha(2)beta(2)gamma(3)-AMPK trimeric complex in skeletal muscle during exercise in humans
Treebak, Jonas Thue, Birk, Jesper Bratz, Rose, A. J., Kiens, Bente, Richter, Erik A. & Wojtaszewski, Jørgen F P, 2007, In: American Journal of Physiology-Endocrinology and Metabolism.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Phenoxyacetic acid derivatives as CRTH2 receptor ligands, their preparation, pharmaceutical compositions, and use in therapy
Ulven, Trond, Frimurer, Thomas Michael, Rist, Ø., Kostenis, E., Högberg, T., Receveur, J. & Grimstrup, M., 2007, Patent No. WO 2007/062678 A1Research output: Patent
- Published
Thiazole- and pyrimidineacetic acid derivatives as CRTH2 receptor ligands, their preparation, pharmaceutical compositions, and use in therapy
Ulven, Trond, Frimurer, Thomas Michael, Rist, Ø., Kostenis, E., Högberg, T., Receveur, J. & Grimstrup, M., 2007, Patent No. WO 2007/062677 A1Research output: Patent
- Published
Common variation in LMNA increases susceptibility to type 2 diabetes and associates with elevated fasting glycemia and estimates of body fat and height in the general population: studies of 7,495 Danish whites
Wegner, L., Andersen, G., Sparsø, T., Grarup, Niels, Glümer, C., Borch-Johnsen, K., Jørgensen, T., Hansen, Torben & Pedersen, Oluf Borbye, 2007, In: Diabetes. 56, 3, p. 694-8 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pointwise and Genomewide Significance Calculations in Gene Mapping through Nonparametric Linkage Analysis: Theory, Algorithms and Applications
Ängquist, Lars, 2007, 250 p.Research output: Book/Report › Ph.D. thesis
- Published
Pointwise and Genomewide Significance Calculations in Gene Mapping through Nonparametric Linkage Analysis: Theory, Algorithms and Applications (Summary)
Ängquist, Lars, 2007, In: Qvartilen. 22, 2, p. 25-26Research output: Contribution to journal › Journal article › Research › peer-review
- 2006
- Published
Pairagon+N-SCAN_EST: a model-based gene annotation pipeline
Arumugam, Mani, Wei, C., Brown, R. H. & Brent, M. R., 2006, In: Genome Biology (Online Edition). 7 Suppl 1, p. S5.1-10Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Enigma interacts with adaptor protein with PH and SH2 domains to control insulin-induced actin cytoskeleton remodeling and glucose transporter 4 translocation
Barrès, Romain, Grémeaux, T., Gual, P., Gonzalez, T., Gugenheim, J., Tran, A., Le Marchand-Brustel, Y. & Tanti, J., Nov 2006, In: Molecular Endocrinology. 20, 11, p. 2864-75 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
IRS-1 serine phosphorylation and insulin resistance in skeletal muscle from pancreas transplant recipients
Bouzakri, K., Karlsson, H. K. R., drb459, drb459, Madsbad, Sten, Christiansen, E. & Zierath, Juleen R, Mar 2006, In: Diabetes. 55, 3, p. 785-91 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
EIF4A2 is a positional candidate gene at the 3q27 locus linked to type 2 diabetes in French families
Cheyssac, C., Dina, C., Leprêtre, F., Vasseur-Delannoy, V., Dechaume, A., Lobbens, S., Balkau, B., Ruiz, J., Charpentier, G., Pattou, F., Joly, E., Prentki, M., Hansen, Torben, Pedersen, Oluf Borbye, Vaxillaire, M. & Froguel, P., 2006, In: Diabetes. 55, 4, p. 1171-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fedmens genetik
Echwald, S. M., Larsen, P. J., Pedersen, Oluf Borbye & Sørensen, Thorkild I.A., 2006, In: Ugeskrift for læger. 168, 2, p. 150-152 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A novel -192c/g Mutation in the Proximal P2 Promoter of the Hepatocyte Nuclear Factor-4α Gene (HNF4A) Associates With Late-onset Diabetes
Ek, J., Hansen, S. P., Lajer, M., Nicot, C., Boesgaard, T. W., Pruhova, S., Johansen, A., Albrechtsen, Anders, Yderstraede, K., Lauenborg, J., Parrizas, M., Boj, S. F., Jørgensen, T., Borch-Johnsen, K., Damm, Peter, Ferrer, J., Lebl, J., Pedersen, Oluf Borbye & Hansen, Torben, 2006, In: Diabetes. 55, 6, p. 1869-73 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PROactive study
Gaede, P., Parving, H. & Pedersen, Oluf Borbye, 2006, In: Lancet. 367, 9504, p. 23-4; author reply 26-7Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular properties of adult mouse gastric and intestinal epithelial progenitors in their niches
Giannakis, M., Stappenbeck, T. S., Mills, J. C., Leip, D. G., Lovett, M., Clifton, S. W., Ippolito, J. E., Glasscock, J. I., Arumugam, Mani, Brent, M. R. & Gordon, J. I., 2006, In: Journal of Biological Chemistry. 281, 16, p. 11292-300 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Timing of Ca2+ response in pancreatic beta-cells is related to mitochondrial mass
Gustavsson, N., Abedi, G., Larsson-Nyrén, G. & Lindström, P., 24 Feb 2006, In: Molecular Cell Biology Research Communications. 340, 4, p. 1119-24 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cell specificity of the cytoplasmic Ca2+ response to tolbutamide is impaired in beta-cells from hyperglycemic mice
Gustavsson, N., Larsson-Nyrén, G. & Lindström, P., Aug 2006, In: The Journal of endocrinology. 190, 2, p. 461-70 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association between neuromedin U gene variants and overweight and obesity
Hainerová, I., Torekov, Signe Sørensen, Ek, J., Finková, M., Borch-Johnsen, K., Jørgensen, T., Madsen, O. D., Lebl, J., Hansen, Torben & Pedersen, Oluf Borbye, 2006, In: Journal of Clinical Endocrinology and Metabolism. 91, 12, p. 5057-63 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Endocannabinoids
Hansen, Harald S., Petersen, G., Artmann, A. & Madsen, A. N., 1 Jan 2006, In: European Journal of Lipid Science and Technology. 108, 10, p. 877-889 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
IL6 gene promoter polymorphisms and type 2 diabetes: joint analysis of individual participants' data from 21 studies
Huth, C., Heid, I. M., Vollmert, C., Gieger, C., Grallert, H., Wolford, J. K., Langer, B., Thorand, B., Klopp, N., Hamid, Y. H., Pedersen, O., Hansen, T., Lyssenko, V., Groop, L., Meisinger, C., Döring, A., Löwel, H., Lieb, W., Hengstenberg, C., Rathmann, W. & 25 others, , 2006, In: Diabetes. 55, 10, p. 2915-21 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variation in CAPN10 in relation to type 2 diabetes, obesity and quantitative metabolic traits: studies in 6018 whites
Jensen, D. P., Urhammer, S. A., Eiberg, Hans Rudolf Lytchoff, Borch-Johnsen, K., Jørgensen, T., Hansen, Torben & Pedersen, Oluf Borbye, 2006, In: Molecular Genetics and Metabolism. 89, 4, p. 360-7 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lens fluorescence in relation to glucose tolerance and genetic predisposition to type 2 diabetes mellitus in a population-based study
Koefoed Theil, P., Kessel, Line, Hansen, Torben, Lund-Andersen, H., Pedersen, Oluf Borbye & Larsen, Michael, 2006, In: Current Eye Research. 31, 9, p. 733-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1α
Lagouge, M., Argmann, C., Gerhart-Hines, Zach, Meziane, H., Lerin, C., Daussin, F., Messadeq, N., Milne, J., Lambert, P., Elliott, P., Geny, B., Laakso, M., Puigserver, P. & Auwerx, J., 15 Dec 2006, In: Cell. 127, 6, p. 1109-1122 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molekylaer patogenese ved monogen og polygen fedme
Larsen, P. J., Echwald, S. M., Sørensen, Thorkild I.A. & Pedersen, Oluf Borbye, 2006, In: Ugeskrift for Laeger. 168, 2, p. 152-5 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Serum ionised calcium and cardiovascular disease in 45-years old men and women followed for 18 years
Ogard, C. G., Petersen, Janne, Jørgensen, T., Almdal, Thomas Peter, drb459, drb459 & drb459, drb459, 2006, In: European Journal of Epidemiology. 21, 2, p. 123-7 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Monitoring kidney function in type 2 diabetic patients with incipient and overt diabetic nephropathy
Rossing, Peter, Rossing, K., Gaede, P., Pedersen, Oluf Borbye & Parving, H., 2006, In: Diabetes Care. 29, 5, p. 1024-30 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genotype-by-nutrient interactions assessed in European obese women: a case-only study
Santos, J. L., Boutin, P., Verdich, C., Holst, C., Larsen, L. H., Toubro, S., Dina, C., Saris, W. H. M., Blaak, E. E., Hoffstedt, J., Taylor, M. A., Polak, J., Clement, K., Langin, D., Astrup, A., Froguel, P., Pedersen, Oluf Borbye, Sørensen, Thorkild I.A., Martinez, J. A. & NUGENOB* consortium, N. C., 2006, In: European Journal of Nutrition. 45, 8, p. 454-462 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic polymorphisms and weight loss in obesity: a randomised trial of hypo-energetic high- versus low-fat diets
Sørensen, T. I. A., Boutin, P., Taylor, M. A., Larsen, L. H., Verdich, C., Petersen, L., Holst, C., Echwald, S. M., Dina, C., Toubro, S., Petersen, M., Polak, J., Clément, K., Martinez, J. A., Langin, D., Oppert, J-M., Stich, V., Macdonald, I., Arner, P., Saris, W. H. M. & 3 others, , 2006, In: PLoS Clinical Trials. 12, 2, p. 1-14 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Critical nodes in signalling pathways: insights into insulin action
Taniguchi, C. M., Emanuelli, Brice & Kahn, C. R., Feb 2006, In: Nature Reviews. Molecular Cell Biology. 7, 2, p. 85-96 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A liver specific gene that is expressed in growth hormone transgenic mice and in normal female mice as a function of age
Tiong, J. D. R., Gosney, E., Ding, J., Chin, E. & Kopchick, J. J., 1 Jun 2006, In: Growth Hormone and IGF Research. 16, 3, p. 145-156 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variants in the 5' region of the neuropeptide Y receptor Y2 gene (NPY2R) are associated with obesity in 5,971 white subjects
Torekov, Signe Sørensen, Larsen, L. H., Andersen, G., Albrechtsen, Anders, Glümer, C., Borch-Johnsen, K., Jørgensen, Tina, Hansen, Teis Schjals & Pedersen, Oluf Borbye, 2006, In: Diabetologia. 49, 11, p. 2653-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
AMPK-mediated AS160 phosphorylation in skeletal muscle is dependent on AMPK catalytic and regulatory subunits.
Treebak, Jonas Thue, Glund, S., Deshmukh, Atul Shahaji, Klein, D. K., Long, Y. C., Jensen, Thomas Elbenhardt, Jørgensen, S. B., Viollet, B., Andersson, L., Neumann, D., Wallimann, T., Richter, Erik A., Chibalin, A. V., Zierath, J. R. & Wojtaszewski, Jørgen F P, 2006, In: Diabetes. 55, 7, p. 2051-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of the calpain-10 gene with type 2 diabetes in Europeans: results of pooled and meta-analyses
Tsuchiya, T., Schwarz, P. E. H., Bosque-Plata, L. D., Geoffrey Hayes, M., Dina, C., Froguel, P., Wayne Towers, G., Fischer, S., Temelkova-Kurktschiev, T., Rietzsch, H., Graessler, J., Vcelák, J., Palyzová, D., Selisko, T., Bendlová, B., Schulze, J., Julius, U., Hanefeld, M., Weedon, M. N., Evans, J. C. & 12 others, , 2006, In: Molecular Genetics and Metabolism. 89, 1-2, p. 174-84 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
6-Acylamino-2-amino-4-methylquinolines as potent melanin-concentrating hormone 1 receptor antagonists
Ulven, Trond, Little, P. B., Receveur, J., Frimurer, Thomas Michael, Rist, Ø., Nørregaard, P. K., Mathiesen, Jesper M. & Högberg, T., 2006, In: Bioorganic & Medicinal Chemistry Letters. 16, 4, p. 1070-1075 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Novel selective orally active CRTH2 antagonists for allergic inflammation developed from in silico derived hits
Ulven, Trond, Receveur, J., Grimstrup, M., Rist, Ø., Frimurer, Thomas Michael, Gerlach, L., Mathiesen, Jesper M., Kostenis, E., Uller, L. & Högberg, T., 2006, In: Journal of Medicinal Chemistry. 49, 23, p. 6638-6641 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Body mass, fat-free body mass, and prognosis in patients with chronic obstructive pulmonary disease from a random population sample: findings from the Copenhagen City Heart Study
Vestbo, J., Prescott, Eva, Almdal, Thomas Peter, Dahl, M., Nordestgaard, Børge, Andersen, T., Sørensen, Thorkild I.A. & Lange, Peter, 2006, In: American Journal of Respiratory and Critical Care Medicine. 173, 1, p. 79-83 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biases in the perceived timing of perisaccadic perceptual and motor events
Yarrow, K., Whiteley, Louise, Haggard, P. & Rothwell, J. C., 2006, In: Attention, Perception & Psychophysics. 68, 7, p. 1217-26 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spatial consequences of bridging the saccadic gap
Yarrow, K., Whiteley, Louise, Rothwell, J. C. & Haggard, P., 2006, In: Vision Research. 46, 4, p. 545-55 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity
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Determinants of plasma levels of proglucagon and the metabolic impact of glucagon receptor signalling: a UK Biobank study
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