- 2011
- Published
Tracking of leptin, soluble leptin receptor, and the free leptin index during weight loss and regain in children
Holm, J., Gamborg, M., Ward, L. C., Gammeltoft, S., Kaas-Ibsen, K., Heitmann, B. L. & Sørensen, Thorkild I.A., 2011, In: Obesity Facts. 4, 6, p. 461-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Loss of Incretin Effect Is a Specific, Important, and Early Characteristic of Type 2 Diabetes
Holst, Jens Juul, Knop, Filip Krag, Vilsbøll, Tina, Krarup, T. & Madsbad, Sten, May 2011, In: Diabetes Care. 34, Supplement 2, p. S251-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neuroprotective properties of GLP-1: theoretical and practical applications
Holst, Jens Juul, Burcelin, R. & Nathanson, E., 2011, In: Current Medical Research and Opinion. 27, 3, p. 547-58 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Postprandial insulin secretion after gastric bypass surgery: the role of glucagon-like peptide 1
Holst, Jens Juul, Sep 2011, In: Diabetes. 60, 9, p. 2203-2205 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulation of glucagon secretion by incretins
Holst, Jens Juul, Christensen, M., Lund, A., de Heer, J., Svendsen, B., Kielgast, U. & Knop, Filip Krag, Oct 2011, In: Diabetes, Obesity and Metabolism. 13 , Suppl 1, p. 89-94 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association between CST3 rs2424577 polymorphism and corpulence related phenotypes during lifetime in populations of European ancestry
Hooton, H., Dubern, B., Henegar, C., Paternoster, L., Nohr, E. A., Alili, R., Rousseau, F., Pelloux, V., Galan, P., Hercberg, S., Arner, P., Sørensen, Thorkild I.A. & Clément, K., 2011, In: Obesity Facts. 4, 2, p. 131-44 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The minor C-allele of rs2014355 in ACADS is associated with reduced insulin release following an oral glucose load
Hornbak, M., Banasik, Karina, Justesen, Johanne Marie, Krarup, N. T., Sandholt, C. H., Andersson, Åsa, Sandbaek, A., Lauritzen, T., Pisinger, C., Witte, D. R., Sørensen, Thorkild I.A., Pedersen, Oluf Borbye & Hansen, Torben, 6 Jan 2011, In: BMC Medical Genetics. 12, 1, p. 4 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucose tolerance, insulin sensitivity and insulin release in European non-diabetic carriers of a polymorphism upstream of CDKN2A and CDKN2B
Hribal, M. L., Presta, I., Procopio, T., Marini, M. A., Stancáková, A., Kuusisto, J., Andreozzi, F., Hammarstedt, A., Jansson, P., Grarup, N., Hansen, Torben, Walker, M., Stefan, N., Fritsche, A., Häring, H. U., Pedersen, Oluf Borbye, Smith, U., Laakso, M., Sesti, G. & EUGENE2 Consortium, E. C., 2011, In: Diabetologia. 54, 4, p. 795-802 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A role for coding functional variants in HNF4A in type 2 diabetes susceptibility
Jafar-Mohammadi, B., Groves, C. J., Gjesing, A. P., Herrera, B. M., Winckler, W., Stringham, H. M., Morris, A. P., Lauritzen, T., Doney, A. S. F., Morris, A. D., Weedon, M. N., Swift, A. J., Kuusisto, J., Laakso, M., Altshuler, D., Hattersley, A. T., Collins, F. S., Boehnke, M., Hansen, T., Pedersen, O. & 5 others, , Jan 2011, In: Diabetologia. 54, 1, p. 111-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma phospholipid long-chain n-3 polyunsaturated fatty acids and body weight change
Jakobsen, M. U., Dethlefsen, C., Due, K. M., Slimani, N., Chajès, V., May, A. M., Sørensen, T. I. A., Halkjær, J., Tjønneland, A., Clavel-Chapelon, F., Boutron-Ruault, M-C., Fagherazzi, G., Teucher, B., Kaaks, R., Boeing, H., Schütze, M., Trichopoulou, A., Zylis, D., Makrygiannis, G., Palli, D. & 21 others, , 2011, In: Obesity Facts. 4, 4, p. 312-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
FoxO3A promotes metabolic adaptation to hypoxia by antagonizing Myc function
Jensen, K. S., Binderup, Tina, Jensen, K. T., Therkelsen, I., Borup, R., Nilsson, E., Multhaupt, H., Bouchard, C., Quistorff, B., Kjær, Andreas, Landberg, G. & Staller, P., 16 Nov 2011, In: E M B O Journal. 30, 22, p. 4554-70 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Foetal proglucagon processing in relation to adult appetite control: lessons from a transplantable rat glucagonoma with severe anorexia
Jensen, P. B., Larsen, P. J., Karlsen, C., Jensen, H. I., Holst, Jens Juul & Madsen, O. D., Oct 2011, In: Diabetes, Obesity and Metabolism. 13 , Suppl. 1, p. 60-68 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome wide association study identifies KCNMA1 contributing to human obesity
Jiao, H., Arner, P., Hoffstedt, J., Brodin, D., Dubern, B., Czernichow, S., van't Hooft, F., Axelsson, T., Pedersen, Oluf Borbye, Hansen, Torben, Sørensen, Thorkild I.A., Hebebrand, J., Kere, J., Dahlman-Wright, K., Hamsten, A., Clement, K. & Dahlman, I., 2011, In: B M C Medical Genomics. 4, p. 51 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production
Jing, E., Emanuelli, Brice, Hirschey, M. D., Boucher, J., Lee, K. Y., Lombard, D., Verdin, E. M. & Kahn, C. R., 30 Aug 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 35, p. 14608-13 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Education modifies genetic and environmental influences on BMI
Johnson, W., Kyvik, K. O., Skytthe, A., Deary, I. J. & Sørensen, Thorkild I.A., 2011, In: P L o S One. 6, 1, p. e16290Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gastric bypass and duodenal and gastric feeding: a comment to Hansen et al
Jorgensen, N. B., Dirksen, C., Holst, Jens Juul & Madsbad, Sten, 2011, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 301, 5, p. G938-G9389 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic variation within the TRPM5 locus associates with prediabetic phenotypes in subjects at increased risk for type 2 diabetes
Ketterer, C., Müssig, K., Heni, M., Dudziak, K., Randrianarisoa, E., Wagner, R., Machicao, F., Stefan, N., Holst, Jens Juul, Fritsche, A., Häring, H. & Staiger, H., 2011, In: Metabolism. 60, 9, p. 1325-1333 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antidiabetic actions of endogenous and exogenous GLP-1 in type 1 diabetic patients with and without residual ß-cell function
Kielgast, U., Holst, Jens Juul & Madsbad, Sten, May 2011, In: Diabetes. 60, 5, p. 1599-1607 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Four weeks of treatment with liraglutide reduces insulin dose without loss of glycemic control in type 1 diabetic patients with and without residual beta-cell function
Kielgast, U., Krarup, T., Holst, Jens Juul, Madsbad, Sten & Krarup, T., Jul 2011, In: Diabetes Care. 34, 7, p. 1463-1468 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome sequencing reveals insights into physiology and longevity of the naked mole rat
Kim, E. B., Fang, X., Fushan, A. A., Huang, Z., Lobanov, A. V., Han, L., Marino, S. M., Sun, X., Turanov, A. A., Yang, P., Yim, S. H., Zhao, X., Kasaikina, M. V., Stoletzki, N., Peng, C., Polak, P., Xiong, Z., Kiezun, A., Zhu, Y., Chen, Y. & 16 others, , 2011, In: Nature Photographer. 479, 7372, p. 223-7 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Estimation of allele frequency and association mapping using next-generation sequencing data
Kim, S. Y., Lohmueller, K. E., Albrechtsen, Anders, Li, Y., Korneliussen, Thorfinn Sand, Tian, G., Grarup, N., Jiang, T., Andersen, G., Witte, D., Jorgensen, T., Hansen, Torben, Pedersen, Oluf Borbye, Wang, J. & Nielsen, Rasmus, 2011, In: B M C Bioinformatics. 12, p. 231 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of the relative contributions of intra-abdominal and liver fat to components of the metabolic syndrome
Kotronen, A., Yki-Järvinen, H., Sevastianova, K., Bergholm, R., Hakkarainen, A., Pietiläinen, K. H., Juurinen, L., Lundbom, N. & Sørensen, Thorkild I.A., 2011, In: Obesity. 19, 1, p. 23-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Associations between APOE variants and metabolic traits and the impact of psychological stress
Kring, S. I. I., Barefoot, J., Brummett, B. H., Boyle, S. H., Siegler, I. C., Toubro, S., Hansen, T., Astrup, A., Pedersen, Oluf Borbye, Williams, R. B. & Sørensen, Thorkild I.A., 2011, In: PLoS ONE. 6, 1, 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A low glycemic index diet does not affect postprandial energy metabolism but decreases postprandial insulinemia and increases fullness ratings in healthy women
Krog-Mikkelsen, I., Sloth, B., Dimitrov, D., Tetens, Inge , Björck, I., Flint, A., Holst, Jens Juul, Astrup, A., Elmstähl, H. & Raben, Anne, 2011, In: Journal of Nutrition. 141, 9, p. 1679-1684 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effects of L-arabinose on intestinal sucrase activity: dose-response studies in vitro and in humans
Krog-Mikkelsen, I., Hels, O., Tetens, Inge , Holst, Jens Juul, Andersen, Jens Rikardt & Bukhave, K., 2011, In: American Journal of Clinical Nutrition. 94, 2, p. 472-478 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Allelic variants of melanocortin 3 receptor gene (MC3R) and weight loss in obesity: a randomised trial of hypo-energetic high- versus low-fat diets
L. Santos, J., De la Cruz, R., Holst, C., Grau, K., Naranjo, C., Maiz, A., Astrup, A., Saris, W. H. M., MacDonald, I., Oppert, J., Hansen, T., Pedersen, Oluf Borbye, Sørensen, Thorkild I.A., Martinez, J. A. & NUGENOB Consortium, 2011, In: P L o S One. 6, 6, p. e199934 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effects of adding group-based lifestyle counselling to individual counselling on changes in plasma glucose levels in a randomized controlled trial: the Inter99 study
Lau, C., Vistisen, D., Toft, U., Tetens, Inge , Glümer, C., Pedersen, Oluf Borbye, Jørgensen, T. & Borch-Johnsen, K., 2011, In: Diabetes & Metabolism. 37, 6, p. 546-52 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The influence of parental history of diabetes and offspring birthweight on offspring glucose metabolism in adulthood
Lauenborg, J., Jørgensen, M. K., Damm, Peter, Major-Pedersen, A., Eiberg, Hans Rudolf Lytchoff, Urhammer, S., Pedersen, Oluf Borbye & Hansen, Torben, Dec 2011, In: Acta Obstetricia et Gynecologica Scandinavica. 90, 12, p. 1357-1363 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dissociated incretin hormone response to protein versus fat ingestion in obese subjects
Lindgren, O., Carr, R., Holst, Jens Juul, Deacon, Carolyn F. & Ahren, B., Jul 2011, In: Diabetes, Obesity and Metabolism Online. 13, 9, p. 863-865 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incretin hormone and insulin responses to oral versus intravenous lipid administration in humans
Lindgren, O., Carr, R. D., Deacon, Carolyn F., Holst, Jens Juul, Pacini, G., Mari, A. & Ahrén, B., Aug 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 8, p. 2519-2524 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Endocrine parameters and phenotypes of the growth hormone receptor gene disrupted (GHR-/-) mouse
List, E. O., Sackmann-Sala, L., Berryman, D. E., Funk, K., Kelder, B., Gosney, E. S., Okada, S., Ding, J., Cruz-Topete, D. & Kopchick, J. J., 1 Jun 2011, In: Endocrine Reviews. 32, 3, p. 356-386 31 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
Lohmueller, K. E., Albrechtsen, Anders, Li, Y., Kim, S. Y., Korneliussen, Thorfinn Sand, Vinckenbosch, N., Tian, G., Huerta-Sanchez, E., Feder, A. F., Grarup, N., Jørgensen, T., Jiang, T., Witte, D. R., Sandbæk, A., Hellmann, I., Lauritzen, T., Hansen, Torben, Pedersen, Oluf Borbye, Wang, J. & Nielsen, Rasmus, 2011, In: P L o S Genetics. 7, 10, 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased lipolysis and energy expenditure in a mouse model with severely impaired glucagon secretion
Lou, P., Gustavsson, N., Wang, Y., Radda, G. K. & Han, W., 2011, In: PloS one. 6, 10, p. e26671Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The separate and combined impact of the intestinal hormones, GIP, GLP-1, and GLP-2, on glucagon secretion in type 2 diabetes
Lund, Asger Bach, Vilsbøll, Tina, Bagger, J. I., Holst, Jens Juul & Knop, Filip Krag, 2011, In: American Journal of Physiology: Endocrinology and Metabolism. 300, 6, p. E1038-E1046 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pleiotropic effects of GIP on islet function involve osteopontin
Lyssenko, V., Eliasson, L., Kotova, O., Pilgaard, K., Wierup, N., Salehi, A., Wendt, A., Jonsson, A. E., De Marinis, Y. Z., Berglund, L. M., Taneera, J., Balhuizen, A., Hansson, O., Osmark, P., Dunér, P., Brøns, C., Stancáková, A., Kuusisto, J., Bugliani, M., Saxena, R. & 19 others, , Sep 2011, In: Diabetes. 60, 9, p. 2424-33 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exenatide reduces reperfusion injury in patients with ST-segment elevation myocardial infarction
Lønborg, Jacob Thomsen, Vejlstrup, N., Kelbæk, H., Bøtker, H. E., Kim, W. Y., Mathiasen, A. B., Jørgensen, E., Helqvist, S., Saunamäki, K., Clemmensen, P., Holmvang, Lene, Thuesen, L., Krusell, L. R., Jensen, J. S., Køber, Lars Valeur, Treiman, M., Holst, Jens Juul & Engstrøm, Thomas, 2011, In: European Heart Journal. 33, 12, p. 1491-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dietary leucine--an environmental modifier of insulin resistance acting on multiple levels of metabolism
Macotela, Y., Emanuelli, Brice, Bång, A. M., Espinoza, D. O., Boucher, J., Beebe, K., Gall, W. & Kahn, C. R., 2011, In: PLOS ONE. 6, 6, p. e21187Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An overview of once-weekly glucagon-like peptide-1 receptor agonists--available efficacy and safety data and perspectives for the future
Madsbad, Sten, Kielgast, U., Asmar, M., Deacon, Carolyn F., Torekov, Signe Sørensen & Holst, Jens Juul, May 2011, In: Diabetes, Obesity and Metabolism. 13, 5, p. 394-407 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Direct effects of FGF21 on glucose uptake in human skeletal muscle: implications for type 2 diabetes and obesity
Mashili, F. L., Austin, R. L., Deshmukh, Atul Shahaji, Fritz, T., Caidahl, K., Bergdahl, K., Zierath, Juleen R, Chibalin, A. V., Moller, D. E., Kharitonenkov, A. & Krook, A., Mar 2011, In: Diabetes - Metabolism: Research and Reviews (Print Edition). 27, 3, p. 286-97 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Loss of inverse relationship between pulsatile insulin and glucagon secretion in patients with type 2 diabetes
Menge, B. A., Grüber, L., Jørgensen, S. M., Deacon, Carolyn F., Schmidt, W. E., Veldhuis, J. D., Holst, Jens Juul & Meier, J. J., Aug 2011, In: Diabetes. 60, 8, p. 2160-2168 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GIP does not potentiate the antidiabetic effects of GLP-1 in hyperglycemic patients with type 2 diabetes
Mentis, N., Vardarli, I., Köthe, L. D., Holst, Jens Juul, Deacon, Carolyn F., Theodorakis, M., Meier, J. J. & Nauck, M. A., 2011, In: Diabetes. 60, 4, p. 1270-1276 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanism-based population modelling for assessment of L-cell function based on total GLP-1 response following an oral glucose tolerance test
Møller, J. B., Jusko, W. J., Gao, W., Hansen, Torben, Pedersen, Oluf Borbye, Holst, Jens Juul, Overgaard, R. V., Madsen, H. & Ingwersen, S. H., 2011, In: Journal of Pharmacokinetics and Pharmacodynamics. 38, 6, p. 713-25 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Women with bulimia nervosa exhibit attenuated secretion of glucagon-like peptide 1, pancreatic polypeptide, and insulin in response to a meal
Naessén, S., Carlström, K., Holst, Jens Juul, Hellström, P. M. & Hirschberg, A. L., 2011, In: American Journal of Clinical Nutrition. 94, 4, p. 967-972 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma levels of glucagon like peptide-1 associate with diastolic function in elderly men
Nathanson, D., Zethelius, B., Berne, C., Lind, L., Andrén, B., Ingelsson, E., Holst, Jens Juul & Nyström, T., Mar 2011, In: Diabetic Medicine. 28, 3, p. 301-305 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Secretion of glucagon-like peptide-1 (GLP-1) in type 2 diabetes: what is up, what is down?
Nauck, M. A., Vardarli, I., Deacon, Carolyn F., Holst, Jens Juul & Meier, J., 2011, In: Diabetologia. 54, 1, p. 10-18 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rapid tachyphylaxis of the glucagon-like peptide 1-induced deceleration of gastric emptying in humans
Nauck, M. A., Kemmeries, G., Holst, Jens Juul & Meier, J. J., 2011, In: Diabetes. 60, 5, p. 1561-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Short sleep duration as a possible cause of obesity: critical analysis of the epidemiological evidence
Nielsen, L. S., Danielsen, K. & Sørensen, Thorkild I.A., 2011, In: Obesity Reviews. 12, 2, p. 78-92 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Type 2 diabetes risk allele near CENTD2 is associated with decreased glucose-stimulated insulin release
Nielsen, T., Sparsø, T., Grarup, N., Jørgensen, T., Pisinger, C. H., Witte, D. R., Hansen, T., Pedersen, Oluf Borbye & Diabetes Genetics Replication and Meta-analysis (DIAGRAM) Consortium, D. G. R. A. M. (. C., 1 May 2011, In: Diabetologica. 54, 5, p. 1052-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Administration of a dipeptidyl peptidase IV inhibitor enhances the intestinal adaptation in a mouse model of short bowel syndrome
Okawada, M., Holst, Jens Juul & Teitelbaum, D. H., Aug 2011, In: Surgery. 150, 2, p. 217-223 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Opportunities for European obesity research in the coming decade - a perspective from the European association for the study of obesity (EASO)
Oppert, J., Sørensen, Thorkild I.A., Hebebrand, J., Woodward, E. & Blundell, J. E., 2011, In: Obesity Facts. 4, 6, p. 425-6 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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The isoenzyme pattern of LDH does not play a physiological role; except perhaps during fast transitions in energy metabolism
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Determinants of plasma levels of proglucagon and the metabolic impact of glucagon receptor signalling: a UK Biobank study
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Targeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment
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