Novo Nordisk Foundation Center for Basic Metabolic Research

  1. Published

    Overweight Patterns Between Childhood and Early Adulthood and Esophageal and Gastric Cardia Adenocarcinoma Risk

    Petrick, J. L., Jensen, B. W., Sørensen, Thorkild I.A., Cook, M. B. & Baker, J. L., 2019, In: Obesity. 27, 9, p. 1520-1526 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Introduction of enteral food increases plasma GLP-2 and decreases GLP-2 receptor mRNA abundance during pig development

    Petersen, Y. M., Hartmann, Bolette, Holst, Jens Juul, Le Huerou-Luron, I., Bjørnvad, Charlotte Reinhard & Sangild, Per Torp, Jun 2003, In: Journal of Nutrition. 133, 6, p. 1781-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Use of a tourniquet is not associated with increased risk of venous thromboembolism after fast-track total knee arthroplasty: a prospective multicenter cohort study of 16,250 procedures

    Petersen, P. B., Mikkelsen, M., Jørgensen, C. C., Kappel, A., Troelsen, Anders, Kehlet, Henrik, Gromov, Kirill, Madsen, F., Hansen, Torben, Laursen, M., Varnum, C., Andersen, Mikkel Rathsach, Krarup, N. H. & wcr491, wcr491, 2023, In: Acta Orthopaedica. 94, p. 342-347 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Venous thromboembolism after fast-track elective revision hip and knee arthroplasty – A multicentre cohort study of 2814 unselected consecutive procedures

    Lundbeck Foundation Centre for Fast-track Hip and Knee Arthroplasty collaborating group, L. F. C. F. F. H. A. K. A. C. G., Mar 2021, In: Thrombosis Research. 199, p. 101-105 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Inhibiting RHOA Signaling in Mice Increases Glucose Tolerance and Numbers of Enteroendocrine and Other Secretory Cells in the Intestine

    Petersen, N., Frimurer, Thomas Michael, Pedersen, M. T., Egerod, Kristoffer Lihme, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Grapin-Botton, A., Jensen, Kim Bak & Schwartz, Thue W., 2018, In: Gastroenterology. 155, 4, p. 1164-1176 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Generation of L cells in mouse and human small intestine organoids

    Petersen, N., Reimann, F., Bartfeld, S., Farin, H. F., Ringnalda, F. C., Vries, R. G. J., van den Brink, S., Clevers, H., Gribble, F. M. & de Koning, E. J. P., Feb 2014, In: Diabetes. 63, 2, p. 410-20 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Three-Dimensional Explant Platform for Studies on Choroid Plexus Epithelium

    Petersen, N., Pedersen, Lola Julie Torz, Jensen, Kristian HR, Hjortø, Gertrud Malene, Spiess, Katja & Rosenkilde, Mette, 2020, In: Frontiers in Cellular Neuroscience. 14, 11 p., 108.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Studies based on the Danish Adoption Register: schizophrenia, BMI, smoking, and mortality in perspective

    Petersen, L. & Sørensen, Thorkild I.A., 2011, In: Scandinavian Journal of Public Health. 39, 7 Suppl, p. 191-5 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Genetic influences on incidence and case-fatality of infectious disease

    Petersen, L., Andersen, Per Kragh & Sørensen, Thorkild I.A., 1 Jan 2010, In: P L o S One. 5, 5, p. e10603

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Delayed age at transfer of adoptees to adoptive parents is associated with increased mortality irrespective of social class of the adoptive parents: a cohort study

    Petersen, L., Andersen, Per Kragh, Sørensen, Thorkild I.A. & Mortensen, Erik Lykke, 2018, In: BMC Public Health. 18, 1, 7 p., 435.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    The Danish Adoption Register

    Petersen, L. & Sørensen, Thorkild I.A., 2011, In: Scandinavian Journal of Public Health. 39, 7 Suppl, p. 83-6 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Genetic and familial environmental effects on suicide attempts: A study of Danish adoptees and their biological and adoptive siblings

    Petersen, L., Sørensen, Thorkild I.A., Andersen, Per Kragh, Mortensen, P. B. & Hawton, K., Feb 2014, In: Journal of Affective Disorders. 155, p. 273-277 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Genetic and Familial Environmental Effects on Suicide - An Adoption Study of Siblings

    Petersen, L., Sørensen, Thorkild I.A., Andersen, Per Kragh, Mortensen, P. B. & Hawton, K., 17 Oct 2013, In: P L o S One. 8, 10, p. e77973

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Genetic and environmental effects on mortality before age 70 years

    Petersen, L., Andersen, Per Kragh, Sørensen, Thorkild I.A., Petersen, L., Andersen, P. K. & Sørensen, Thorkild I.A., 1 May 2008, In: Epidemiology. 19, 3, p. 472-6 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Assessment of Hepatic Mitochondrial Oxidation and Pyruvate Cycling in NAFLD by (13)C Magnetic Resonance Spectroscopy

    Petersen, K. M. F., Befroy, D. E., Dufour, S., Rothman, D. L. & Shulman, G. I., 12 Jul 2016, In: Cell Metabolism. 24, 1, p. 167-71 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Ethnic and sex differences in hepatic lipid content and related cardiometabolic parameters in lean individuals

    Petersen, K. F., Dufour, S., Li, F., Rothman, D. L. & Shulman, G. I., 2022, In: JCI insight. 7, 7, 10 p., e157906.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Hemodynamic Effects of Glucagon: A Literature Review

    Petersen, K. M., Bogevig, S., Holst, Jens Juul, Knop, Filip Krag & Christensen, Mikkel Bring, 2018, In: Journal of Clinical Endocrinology & Metabolism. 103, 5, p. 1804-1812

    Research output: Contribution to journalReviewResearchpeer-review

  18. Published

    Response to Letter to the Editor: "Hemodynamic Effects of Glucagon: A Literature Review"

    Petersen, K. M., Bøgevig, S., Holst, Jens Juul, Knop, Filip Krag & Christensen, Mikkel Bring, 2018, In: The Journal of clinical endocrinology and metabolism. 103, 12, p. 4480-4481 2 p.

    Research output: Contribution to journalComment/debateResearch

  19. Published

    High-Dose Glucagon Has Hemodynamic Effects Regardless of Cardiac Beta-Adrenoceptor Blockade: A Randomized Clinical Trial

    Petersen, K. M., Bøgevig, S., Riis, T., Andersson, N. W., Dalhoff, Kim, Holst, Jens Juul, Knop, Filip Krag, Faber, Jens, Petersen, Tonny Studsgaard & Christensen, Mikkel Bring, 2020, In: Journal of the American Heart Association. 9, 21, 27 p., e016828.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Cardiovascular effects of high-dose glucagon: a randomised clinical trial

    Petersen, K. M., Bogevig, S., Riis, T., Andersson, N. A. W., Dalhoff, Kim, Holst, Jens Juul, Knop, Filip Krag, Faber, Jens, Petersen, Tonny Studsgaard & Christensen, Mikkel Bring, 2020, In: Diabetologia. 63, SUPPL 1, p. S231-S231

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  21. Published

    GLP-1-directed NMDA receptor antagonism for obesity treatment

    Petersen, J., Ludwig, M. Q., Juozaityte, V., Ranea-Robles, P., Svendsen, C., Hwang, E., Kristensen, A. W., Fadahunsi, N., Lund, J., Breum, A. W., Mathiesen, C. V., Sachs, L., Moreno-Justicia, R., Rohlfs, R., Ford, J. C., Douros, J. D., Finan, B., Portillo, B., Grose, K., Petersen, J. E. & 13 others, Trauelsen, Mette, Feuchtinger, A., DiMarchi, R. D., Schwartz, Thue W., Deshmukh, Atul Shahaji, Thomsen, Morten Bækgaard, Kohlmeier, Kristi Anne, Williams, K. W., Pers, Tune H, Frølund, Bente, Strømgaard, Kristian, Klein, A. B. & Clemmensen, Christoffer, 2024, In: Nature. 629, 8014, p. 1133–1141

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Designing Poly-agonists for Treatment of Metabolic Diseases: Challenges and Opportunities

    Petersen, Jonas Odgaard, Strømgaard, Kristian, Frølund, Bente & Clemmensen, Christoffer, 2019, In: Drugs. 79, 11, p. 1187-1197 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Free fatty acid receptor 1 stimulates cAMP production and gut hormone secretion through Gq-mediated activation of adenylate cyclase 2

    Petersen, Jacob Emil, Pedersen, M. H., Dmytriyeva, O., Nellemose, E., Arora, Tulika, Engelstoft, M. S., Asher, W. B., Javitch, J. A., Schwartz, Thue W. & Trauelsen, Mette, 2023, In: Molecular Metabolism. 74, 10 p., 101757.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Vejle diabetes Biobank: A resource for studies of the etiologies of diabetes and its comorbidities

    Petersen, E. R. B., Nielsen, A. A., Christensen, H., Hansen, Torben, Pedersen, Oluf Borbye, Christensen, C. K. & Brandslund, I., 21 Oct 2016, In: Clinical Epidemiology. 8, p. 393-413 21 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Cuff inflations do not affect night-time blood pressure: comparison of 24 h ambulatory blood pressure measured by a cuff and a tonometric device in type 2 diabetes

    Petersen, E. H., Theilade, S., Hansen, T. W., Lindhardt, M. K. & Rossing, Peter, Dec 2015, In: Blood Pressure Monitoring. 20, 6, p. 369-72 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Controlled trial of lambda-cyhalothrin impregnated bed nets and Maloprim chemosuppression to control malaria in children living in a holoendemic area of Sierra Leone, west Africa. Study design and preliminary results

    Petersen, E., Marbiah, N. T., Magbiti, E., Lines, J. D., Maude, G. H., Høgh, Birthe, Curtis, C., Greenwood, B. & Bradley, D., Jul 1993, In: Parassitologia. 35 Suppl, p. 81-5 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Parasitaere sygdomme hos patienter med nedsat immunforsvar. Klinisk billede og diagnose

    Petersen, E., Lebech, M., Højlyng, N., Holten-Andersen, W., Mølbak, Kåre, Høgh, Birthe & Jepsen, S., 7 Sep 1992, In: Ugeskrift for Laeger. 154, 37, p. 2475-80 6 p.

    Research output: Contribution to journalReviewResearchpeer-review

  28. Published

    The effect of splenectomy on immunity to Plasmodium malariae and P. falciparum in a malaria immune donor

    Petersen, E., Høgh, Birthe, Marbiah, N. T. & Hanson, A. P., Mar 1992, In: Tropical Medicine and Parasitology. 43, 1, p. 68-9 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Development of immunity against Plasmodium falciparum malaria: clinical and parasitologic immunity cannot be separated

    Petersen, E., Høgh, Birthe, Marbiah, N. T., David, K. & Hanson, A. P., Nov 1991, In: The Journal of Infectious Diseases. 164, 5, p. 949-53 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Clinical and parasitological studies on malaria in Liberian adults living under intense malaria transmission

    Petersen, E., Høgh, Birthe, Marbiah, N. T., Dolopaie, E., Gottschau, A., Hanson, A. P. & Bjorkman, A., Dec 1991, In: Annals of Tropical Medicine and Parasitology. 85, 6, p. 577-84 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Plasma, erythrocyte and urine concentrations of chlorproguanil and two metabolites in man after different doses

    Petersen, E., Flachs, H., Høgh, Birthe, Hanson, A. P., Björkman, A. & Hvidberg, E. F., Jun 1991, In: American Journal of Tropical Medicine and Hygiene. 94, 3, p. 199-205 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Conjugated C-6 hydroxylated bile acids in serum relate to human metabolic health and gut Clostridia species

    Petersen, A. Ø., Julienne, H., Hyötyläinen, T., Sen, P., Fan, Yong, Pedersen, H. K., Jäntti, S., Hansen, T. H., Nielsen, T., Jørgensen, T., Hansen, Torben, Myers, P. N., Nielsen, H. B., Ehrlich, S. D., Orešič, M. & Pedersen, Oluf Borbye, 2021, In: Scientific Reports. 11, 1, 11 p., 13252.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Hypophosphatemia promotes lower rates of muscle ATP synthesis

    Pesta, D. H., Tsirigotis, D. N., Befroy, D. E., Caballero, D., Jurczak, M. J., Rahimi, Y., Cline, G. W., Dufour, S., Birkenfeld, A. L., Rothman, D. L., Carpenter, T. O., Insogna, K., Petersen, K. M. F., Bergwitz, C. & Shulman, G. I., 23 Jun 2016, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 30, 10, p. 3378-3387 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Early growth and postprandial appetite regulatory hormone responses

    Perälä, M., Kajantie, E., Valsta, L. M., Holst, Jens Juul, Leiviskä, J. & Eriksson, J. G., 19 Apr 2013, In: British Journal of Nutrition. 110, 09, p. 1-10 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Renin angiotensin system blockade reduces urinary levels of soluble urokinase plasminogen activator receptor (suPAR) in patients with type 2 diabetes

    Persson, F., Theilade, S., Eugen-Olsen, J., Rossing, Peter & Parving, H., 2016, In: Journal of Diabetes and its Complications. 30, 8, p. 1440-1442 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Meta-analysis of heterogeneous data sources for genome-scale identification of risk genes in complex phenotypes

    Pers, T. H., Hansen, N. T., Hansen, K. L., Koefoed, P., Dworzynski, P., Miller, M. L., Flint, T. J., Mellerup, E., Dam, H., Andreassen, O. A., Djurovic, S., Melle, I., Børglum, A. D., Werge, T., Purcell, S., Ferreira, M. A., Kouskoumvekaki, I., Workman, C., Hansen, T., Mors, O. & 1 others, Brunak, Søren, 11 Apr 2011, In: Genetic Epidemiology. 35, 5, p. 318-332 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Comprehensive analysis of schizophrenia-associated loci highlights ion channel pathways and biologically plausible candidate causal genes

    Pers, Tune H, Timshel, P., Ripke, S., Lent, S., Sullivan, P. F., O'Donovan, M. C., Franke, L., Hirschhorn, J. N. & Schizophrenia Working Group of the Psychiatric Genomics Consortium, S. W. G. O. T. P. G. C., 10 Jan 2016, In: Human Molecular Genetics. 25, 6, p. 1247-1254 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Gene set analysis for interpreting genetic studies

    Pers, Tune H, 1 Oct 2016, In: Human Molecular Genetics. 25, R2, p. R133-R140 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  39. Published

    Assays for detecting arrestin interaction with GPCRs

    Perry-Hauser, N. A., Asher, W. B., Hauge Pedersen, M. & Javitch, J. A., 2021, Biomolecular Interactions Part A. Shukla, A. K. (ed.). Academic Press, p. 43-65 23 p. (Methods in Cell Biology, Vol. 166).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  40. Published

    Reversal of Hypertriglyceridemia, Fatty Liver Disease, and Insulin Resistance by a Liver-Targeted Mitochondrial Uncoupler

    Perry, R. J., Kim, T., Zhang, X., Lee, H., Pesta, D., Popov, V. B., Zhang, D., Rahimi, Y., Jurczak, M. J., Cline, G. W., Spiegel, D. A. & Shulman, G. I., 2013, In: Cell Metabolism. 18, 5, p. 740-748

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Pleotropic effects of leptin to reverse insulin resistance and diabetic ketoacidosis

    Perry, R. J., Petersen, K. F. & Shulman, G. I., 10 Mar 2016, In: Diabetologia. 59, 5, p. 933-937 5 p.

    Research output: Contribution to journalReviewResearchpeer-review

  42. Published

    Acetate mediates a microbiome-brain-β-cell axis to promote metabolic syndrome

    Perry, R. J., Peng, L., Barry, N. A., Cline, G. W., Zhang, D., Cardone, R. L., Petersen, K. F., Kibbey, R. G., Goodman, A. L. & Shulman, G. I., 9 Jun 2016, In: Nature. 534, 7606, p. 213-7 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Imeglimin lowers glucose primarily by amplifying glucose-stimulated insulin secretion in high-fat-fed rodents

    Perry, R. J., Cardone, R. L., Petersen, M. C., Zhang, D., Fouqueray, P., Hallakou-Bozec, S., Bolze, S., Shulman, G. I., Petersen, K. F. & Kibbey, R. G., 1 Aug 2016, In: American Journal of Physiology: Endocrinology and Metabolism. 311, 2, p. E461-70

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    The role of hepatic lipids in hepatic insulin resistance and type 2 diabetes

    Perry, R. J., Samuel, V. T., Petersen, K. M. F. & Shulmann, G. I., 5 Jun 2014, In: Nature. 510, p. 84-91 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Propionate Increases Hepatic Pyruvate Cycling and Anaplerosis and Alters Mitochondrial Metabolism

    Perry, R. J., Borders, C. B., Cline, G. W., Zhang, X., Alves, T. C., Petersen, K. M. F., Rothman, D. L., Kibbey, R. G. & Shulman, G. I., 3 Jun 2016, In: Journal of Biological Chemistry. 291, 23, p. 12161-70 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes

    Perry, J. R. B., Weedon, M. N., Langenberg, C., Jackson, A. U., Lyssenko, V., Sparsø, T., Thorleifsson, G., Grallert, H., Ferrucci, L., Maggio, M., Paolisso, G., Walker, M., Palmer, C. N. A., Payne, F., Young, E., Herder, C., Narisu, N., Morken, M. A., Bonnycastle, L. L., Owen, K. R. & 38 others, Shields, B., Knight, B., Bennett, A., Groves, C. J., Ruokonen, A., Jarvelin, M. R., Pearson, E., Pascoe, L., Ferrannini, E., Bornstein, S. R., Stringham, H. M., Scott, L. J., Kuusisto, J., Nilsson, Carl Martin Peter, Neptin, M., Gjesing, A. P., Pisinger, C., Lauritzen, T., Sandbaek, A., Sampson, M., Zeggini, M. E., Lindgren, C. M., Steinthorsdottir, V., Thorsteinsdottir, U., Hansen, T., Schwarz, Peter, Illig, T., Laakso, M., Stefansson, K., Morris, A. D., Groop, L., Pedersen, Oluf Borbye, Boehnke, M., Barroso, I., Wareham, N. J., Hattersley, A. T., McCarthy, M. I. & Frayling, T. M., 2009, In: Human Molecular Genetics. 19, 3, p. 535-44 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche

    Perry, J. R. B., Day, F., Elks, C. E., Sulem, P., Thompson, D. J., Ferreira, T., He, C., Chasman, D. I., Esko, T., Thorleifsson, G., Albrecht, E., Ang, W. Q., Corre, T., Cousminer, D. L., Feenstra, B., Franceschini, N., Ganna, A., Johnson, A. D., Kjellqvist, S., Lunetta, K. L. & 31 others, McMahon, G., Nolte, I. M., Paternoster, L., Porcu, E., Smith, A. V., Stolk, L., Teumer, A., Tšernikova, N., Tikkanen, E., Ulivi, S., Wagner, E. K., Amin, N., Bierut, L. J., Byrne, E. M., Hottenga, J., Koller, D. L., Mangino, M., Pers, T. H., Yerges-Armstrong, L. M., Hua Zhao, J., Andrulis, I. L., Anton-Culver, H., Atsma, F., Bandinelli, S., Beckmann, M. W., Benitez, J., Bojesen, Stig Egil, Melbye, M., Nohr, E. A., Sørensen, Thorkild I.A. & Australian Ovarian Cancer Study, A. O. C. S., 2014, In: Nature. 514, 7520, p. 92-7 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Early Weight Gain, Linear Growth, and Mid-Childhood Blood Pressure: A Prospective Study in Project Viva

    Perng, W., Rifas-Shiman, S. L., Kramer, M. S., Haugaard, L. K., Oken, E., Gillman, M. W. & Belfort, M. B., Feb 2016, In: Hypertension. 67, 2, p. 301-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Different Malabsorptive Obesity Surgery Interventions Result in Distinct Postprandial Amino Acid Metabolomic Signatures

    Pereira, S. S., Jarak, I., Carvalho, R. A., Oliveira, P. F., Alves, M. G., Guimaraes, M., Almeida, R., Pereira, A. M., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Nora, M. & Monteiro, M. P., 2020, In: Obesity Surgery. 30, p. 4019-4028

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Biliopancreatic diversion with duodenal switch (BPD-DS) and single-anastomosis duodeno-ileal bypass with sleeve gastrectomy (SADI-S) result in distinct post-prandial hormone profiles

    Pereira, S. S., Guimarães, M., Almeida, R., Pereira, A. M., Lobato, C. B., Hartmann, Bolette, Hilsted, Linda, Holst, Jens Juul, Nora, M. & Monteiro, M. P., 2019, In: International Journal of Obesity. 43, p. 2518-2527

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Reply to: “Dietary sucrose induces atherosclerotic diseases more than dietary fat in LDLr−/− ApoB100/100 mice: Is it independent of differences in plasma cholesterol levels?”

    Perazza, L. R., Daniel, N., Mitchell, P. L., Jensen, Benjamin Anderschou Holbech & Marette, A., 2021, In: Atherosclerosis. 325, p. 118-120 3 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  52. Published

    Dietary sucrose induces metabolic inflammation and atherosclerotic cardiovascular diseases more than dietary fat in LDLr−/− ApoB100/100 mice

    Perazza, L. R., Mitchell, P. L., Jensen, Benjamin Anderschou Holbech, Daniel, N., Boyer, M., Varin, T. V., Bouchareb, R., Nachbar, R. T., Bouchard, M., Blais, M., Gagné, A., Joubert, P., Sweeney, G., Roy, D., Arsenault, B. J., Mathieu, P. & Marette, A., 2020, In: Atherosclerosis. 304, p. 9-21 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Fish oil replacement prevents, while docosahexaenoic acid-derived protectin DX mitigates end-stage-renal-disease in atherosclerotic diabetic mice

    Perazza, L. R., Mitchell, P. L., Lizotte, F., Jensen, Benjamin Anderschou Holbech, St-Pierre, P., Trottier, J., Barbier, O., Mathieu, P., Geraldes, P. M. & Marette, A., 2021, In: FASEB Journal. 35, 5, 18 p., 21559.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Hepatic NAD salvage pathway is enhanced in mice on a high-fat diet

    Penke, M., Larsen, P. S., Schuster, S., Dall, M., Jensen, Benjamin Anderschou Holbech, Gorski, T., Meusel, A., Richter, S., Vienberg, S. G., Treebak, Jonas Thue, Kiess, W. & Garten, A., 2015, In: Molecular and Cellular Endocrinology. 412, p. 65-72 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Hepatic NAD Metabolism Is Dysregulated By an Excessive Supply of Lipids

    Penke, M., Treebak, Jonas Thue, Schuster, S., Gorski, T., Garten, A. & Kiess, W., 2014, In: Endocrine Reviews.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Metabolic plasticity and obesity-associated changes in diurnal postexercise metabolism in mice

    Pendergrast, L. A., Ashcroft, Stephen Paul, Ehrlich, Amy M, Treebak, Jonas Thue, Krook, A., Dollet, L. & Zierath, Juleen R, 2024, In: Metabolism: Clinical and Experimental. 155, 12 p., 155834.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Time of day determines postexercise metabolism in mouse adipose tissue

    Pendergrast, L. A., Lundell, L. S., Ehrlich, Amy M, Ashcroft, Stephen Paul, Schönke, M., Basse, A. L., Krook, A., Treebak, Jonas Thue, Dollet, L. & Zierath, Juleen R, 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 8, e2218510120.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Plasma proteomics classifiers improve risk prediction for renal disease in patients with hypertension or type 2 diabetes

    Pena, M. J., Jankowski, J., Heinze, G., Kohl, M., Heinzel, A., Bakker, S. J. L., Gansevoort, R. T., Rossing, Peter, de Zeeuw, D., Heerspink, H. J. L. & Jankowski, V., Oct 2015, In: Journal of Hypertension. 33, 10, p. 2123-32 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Prognostic clinical and molecular biomarkers of renal disease in type 2 diabetes

    Pena, M. J., de Zeeuw, D., Mischak, H., Jankowski, J., Oberbauer, R., Woloszczuk, W., Benner, J., Dallmann, G., Mayer, B., Mayer, G., Rossing, Peter & Lambers Heerspink, H. J., Aug 2015, In: Nephrology, Dialysis, Transplantation. 30, Suppl 4, p. iv86-95

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Identification of protein phosphatase involvement in the AT2 receptor-induced activation of endothelial nitric oxide synthase

    Peluso, A., 2018, In: Clinical Science.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    The angiotensin type 2 receptor and the kidney

    Peluso, A. A. B., Santos, R. A. S., Unger, T. & Steckelings, U. M., 2017, In: Current Opinion in Nephrology and Hypertension.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Age‐dependent decline of NAD+ - universal truth or confounded consensus?

    Peluso, A. A., Damgaard, Mads Vargas, Mori, M. A. S. & Treebak, Jonas Thue, 2021, In: Nutrients. 14, 1, 101.

    Research output: Contribution to journalReviewResearchpeer-review

  63. Published

    Functional assay for assessment of agonistic or antagonistic activity of angiotensin AT2 receptor ligands reveals that EMA401 and PD123319 have agonistic properties

    Peluso, A. A., Souza-Silva, I. M., Villela, D. C., Hansen, P. B. L., Hallberg, A., Bader, M., Santos, R., Sumners, C. & Steckelings, U. M., 2023, In: Biochemical Pharmacology. 216, 12 p., 115793.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Quantitative Phosphoproteomics of the Angiotensin AT2-Receptor Signaling Network Identifies HDAC1 (Histone-Deacetylase-1) and p53 as Mediators of Antiproliferation and Apoptosis

    Peluso, A. A., Kempf, S. J., Verano-braga, T., Rodrigues-ribeiro, L., Johansen, L. E., Hansen, M. R., Kitlen, G., Haugaard, A. H., Sumners, C., Ditzel, H. J., Santos, R. A., Bader, M., Larsen, M. R. & Steckelings, U. M., 2022, In: Hypertension. 79, 11, p. 2530-2541

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Oral supplementation of nicotinamide riboside alters intestinal microbial composition in rats and mice, but not humans

    Peluso, A. A., Lundgaard, A. T., Babaei, P., Mousovich-Neto, F., Rocha, A. L., Damgaard, M. V., Bak, E. G., Gnanasekaran, T., Dollerup, O. L., Trammell, S. A. J., Nielsen, T. S., Kern, T., Abild, C. B., Sulek, K., Ma, T., Gerhart-Hines, Z., Gillum, M. P., Arumugam, M., Ørskov, C., McCloskey, D. & 4 others, Jessen, N., Herrgård, M. J., Mori, M. A. S. & Treebak, Jonas Thue, 2023, In: npj Aging. 9, 21 p., 7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    RAD51B in Familial Breast Cancer

    Pelttari, L. M., Khan, S., Vuorela, M., Kiiski, J. I., Vilske, S., Nevanlinna, V., Ranta, S., Schleutker, J., Winqvist, R., Kallioniemi, A., Dörk, T., Bogdanova, N. V., Figueroa, J., Pharoah, P. D. P., Schmidt, M. K., Dunning, A. M., García-Closas, M., Bolla, M. K., Dennis, J., Michailidou, K. & 31 others, Wang, Q., Hopper, J. L., Southey, M. C., Rosenberg, E. H., Fasching, P. A., Beckmann, M. W., Peto, J., Dos-Santos-Silva, I., Sawyer, E. J., Tomlinson, I., Burwinkel, B., Surowy, H., Guénel, P., Truong, T., Bojesen, Stig Egil, Nordestgaard, Børge, Benitez, J., González-Neira, A., Neuhausen, S. L., Anton-Culver, H., Brenner, H., Arndt, V., Meindl, A., Schmutzler, R. K., Brauch, H., Brüning, T., Lindblom, A., Margolin, S., Mannermaa, A., Hartikainen, J. M. & kConFab/AOCS Investigators, K. I., 2016, In: PLOS ONE. 11, 5, 18 p., e0153788.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Dysregulation of macrophage PEPD in obesity determines adipose tissue fibro-inflammation and insulin resistance

    Pellegrinelli, V., Rodriguez-Cuenca, S., Rouault, C., Figueroa-Juarez, E., Schilbert, H., Virtue, S., Moreno-Navarrete, J. M., Bidault, G., Vázquez-Borrego, M. C., Dias, A. R., Pucker, B., Dale, M., Campbell, M., Carobbio, S., Lin, Y. H., Vacca, M., Aron-Wisnewsky, J., Mora, S., Masiero, M. M., Emmanouilidou, A. & 8 others, Mukhopadhyay, S., Dougan, G., den Hoed, M., Loos, Ruth, Fernández-Real, J. M., Chiarugi, D., Clément, K. & Vidal-Puig, A., 2022, In: Nature Metabolism. 4, 4, p. 476-494 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Effects of Exercise on Lipid-Induced Insulin Resistance in Human Skeletal Muscle-Signaling at the Level of TBC1D4

    Pehmoller, C., Brandt, N., Birk, Jesper Bratz, Treebak, Jonas Thue, Hoeg, L. D., Sjoberg, K. A., Kiens, Bente, Richter, Erik A. & Wojtaszewski, Jørgen F P, 2010, In: Diabetes.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Improving membrane binding as a design strategy for amphipathic peptide hormones: 2-helix variants of PYY3-36

    Pedersen, S. L., Bhatia, V. K., Jurt, S., Paulsson, J. F., Pedersen, M. H., Jørgensen, R., Holst, Birgitte, Stamou, Dimitrios, Vrang, N., Zerbe, O. & Jensen, Knud Jørgen, 2012, In: Journal of Peptide Science. 18, 9, p. 579-587 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Butyrate inhibits IL-1β-induced inflammatory gene expression by suppression of NF-κB activity in pancreatic beta cells

    Pedersen, Signe Schultz, Prause, Michala Cecilie Burstein, Williams, K., Barrès, Romain & Billestrup, Nils, 2022, In: Journal of Biological Chemistry. 298, 9, 14 p., 102312.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Targeted Delivery of Butyrate Improves Glucose Homeostasis, Reduces Hepatic Lipid Accumulation and Inflammation in db/db Mice

    Pedersen, Signe Schultz, Prause, Michala Cecilie Burstein, Sørensen, C., Størling, Joachim, Moritz, Thomas, Mariño, E. & Billestrup, Nils, 2023, In: International Journal of Molecular Sciences. 24, 5, 17 p., 4533.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    Butyrate functions as a histone deacetylase inhibitor to protect pancreatic beta cells from IL-1β-induced dysfunction

    Pedersen, Signe Schultz, Ingerslev, Lars Roed, Olsen, M., Prause, Michala Cecilie Burstein & Billestrup, Nils, 2024, In: FEBS Journal. 291, 3, p. 566-583

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Influence of psychosocial factors on postpartum weight retention

    Pedersen, P., Baker, J. L., Henriksen, T. B., Lissner, L., Heitmann, B. L., Sørensen, Thorkild I.A., Nohr, E. A. & Pedersen, P., 1 Mar 2011, In: Obesity. 19, 3, p. 639-46 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Handlingsplan om diabetes

    Pedersen, Oluf Borbye, 2004, In: Ugeskrift for Laeger. 166, 12, p. 1099

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Jagten på de genetiske determinanter for de formodede polygene former for type 2-diabetes. Status og perspektivering

    Pedersen, Oluf Borbye, Hansen, Torben, Hansen, L., Echwald, S. M. & Urhammer, S. A., 2002, In: Ugeskrift for Laeger. 164, 16, p. 2163-6 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Intensified multifactorial intervention and cardiovascular outcome in type 2 diabetes: the Steno-2 study

    Pedersen, Oluf Borbye & Gaede, P., 2003, In: Metabolism. 52, 8 Suppl 1, p. 19-23 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Intensified multifactorial treatment of patients with Type 2 diabetes: what can be achieved and does it pay off?

    Pedersen, Oluf Borbye, 2009, In: Journal of Diabetes. 1, 2, p. 83-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Porcine glucagon-like peptide-2: structure, signaling, metabolism and effects

    Pedersen, N. B., Hjøllund, K. R., Johnsen, A. H., Ørskov, Cathrine, Rosenkilde, Mette, Hartmann, B. & Holst, Jens Juul, 2007, In: Regulatory Peptides. 146, 1-3, p. 310-320 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    A novel luminescence-based β-arrestin recruitment assay for unmodified receptors

    Pedersen, M. H., Pham, J., Mancebo, H., Inoue, A., Asher, W. B. & Javitch, J. A., 2021, In: Journal of Biological Chemistry. 296, 10 p., 100503.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    GPR40 (FFAR1) – Combined Gs and Gq signaling in vitro is associated with robust incretin secretagogue action ex vivo and in vivo

    Pedersen, M. H., Bentsen, M. A., Husted, Anna Sofie, Ekberg, J. P., Wright, M. J., Di Salvo, J., Weinglass, A. B., Engelstoft, M. S., Madsen, A. N., Lückmann, Michael, Miller, M. W., Trujillo, M. E., Frimurer, Thomas Michael, Holst, Birgitte, Howard, A. D. & Schwartz, Thue W., Jan 2015, In: Molecular Metabolism. 4, 1, p. 3-14 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    Gq and Gs signaling acting in synergy to control GLP-1 secretion

    Pedersen, M. H., Ekberg, J. H., Engelstoft, M. S., Timshel, P., Madsen, A. N. & Schwartz, Thue W., Jul 2017, In: Molecular and Cellular Endocrinology. 449, p. 64-73

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    The effect of dietary fish oil in addition to lifestyle counselling on lipid oxidation and body composition in slightly overweight teenage boys

    Pedersen, M. H., Mølgaard, Christian, Hellgren, L., Matthiessen, J., Holst, Jens Juul & Lauritzen, Lotte, 2011, In: Journal of Nutrition and Metabolism. 2011, 348368, 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Emergence of the obesity epidemic preceding the presumed obesogenic transformation of the society

    Pedersen, M. M., Ekstrøm, Claus Thorn & Sørensen, Thorkild I.A., 2023, In: Science Advances. 9, 37, 7 p., eadg6237.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Copenhagen study of overweight patients with coronary artery disease undergoing low energy diet or interval training: the randomized CUT-IT trial protocol

    Pedersen, L. R., Olsen, R. H., Frederiksen, M., Astrup, A., Chabanova, E., Hasbak, P., Holst, Jens Juul, Kjær, Andreas, Newman, J. W., Walzem, R., Wisløff, U., Sajadieh, Ahmad, Haugaard, Steen Bendix & Prescott, Eva, 2013, In: B M C Cardiovascular Disorders. 13, 1, 8 p., 106.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Standard procedures for blood withdrawal in conscious male rats induce stress and profoundly affect glucose tolerance and secretion of glucoregulatory hormones

    Pedersen, K., Andersen, H., Fledelius, C., Holst, Jens Juul, Hjuler, S. T. & Kuhre, Rune Ehrenreich, 2023, In: Molecular Metabolism. 69, 101689.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Influence of NAFLD and bariatric surgery on hepatic and adipose tissue mitochondrial biogenesis and respiration

    Pedersen, J. S., Rygg, M. O., Chrøis, K., Sustarsic, E. G., Gerhart-Hines, Zach, Wever Albrechtsen, N. J., Serizawa, R. R., Kristiansen, V. B., Basse, A. L., Boilesen, Astrid Elisabeth Bruun, Olsen, B. H., Hansen, Torben, Gluud, Lise Lotte, Madsbad, Sten, Larsen, S., Bendtsen, Flemming & Dela, Flemming, 2022, In: Nature Communications. 13, 15 p., 2931.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Risk of pancreatitis in patients with inflammatory bowel disease - a meta-analysis

    Pedersen, J. E., Ängquist, Lars, Jensen, C. B., Kjærgaard, J. S., Jess, T. & Allin, K. H., 2020, In: Danish Medical Journal. 67, 3, 6 p., A08190427.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Late midlife C-reactive protein and interleukin-6 in middle aged danish men in relation to body size history within and across generations

    Pedersen, J. L. M., Budtz-Joergensen, Esben, Mortensen, Erik Lykke, Bruunsgaard, H., Osler, Merete, Sørensen, Thorkild I.A., Rod, Naja Hulvej & Lund, Rikke, Feb 2016, In: Obesity. 24, 2, p. 461-468 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Low birth weight, adult BMI and inflammation in middle age

    Pedersen, J. L. M., Rod, Naja Hulvej, Avlund, K., Budtz-Joergensen, Esben, Mortensen, Erik Lykke, Sørensen, Thorkild I.A. & Lund, Rikke, 2013, In: Gerontologist. 53, suppl. 1, p. 380

    Research output: Contribution to journalConference articleResearchpeer-review

  90. Published

    Glucagon like-peptide 1 receptor and the liver

    Pedersen, Jens & Holst, Jens Juul, 2011, In: Liver international : official journal of the International Association for the Study of the Liver. 31, 9, p. 1243-5 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Glucose metabolism is altered after loss of L cells and α-cells but not influenced by loss of K cells

    Pedersen, J., Ugleholdt, Randi Kjærsgaard, Jørgensen, S. M., Windeløv, Johanne Agerlin, Grunddal, Kaare Villum, Schwartz, Thue W., Füchtbauer, E., Poulsen, Steen Seier, Holst, Peter Johannes & Holst, Jens Juul, 1 Jan 2013, In: American Journal of Physiology: Endocrinology and Metabolism. 304, 1, p. E60-73 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Human gut microbes impact host serum metabolome and insulin sensitivity

    Pedersen, H. K., Gudmundsdottir, V., Nielsen, H. B., Hyotylainen, T., Nielsen, T., Jensen, B. A. H., Forslund, K., Hildebrand, F., Prifti, E., Falony, G., Le Chatelier, E., Levenez, F., Doré, J., Mattila, I., Plichta, D. R., Pöhö, P., Hellgren, L. I., Arumugam, M., Sunagawa, S., Vieira-Silva, S. & 14 others, Jørgensen, T., Holm, J. B., Trošt, K., Kristiansen, Karsten, Brix, Susanne, Raes, J., Wang, J., Hansen, Torben, Bork, P., Brunak, Søren, Oresic, M., Ehrlich, S. D., Pedersen, Oluf Borbye & MetaHIT Consortium, M. C., 2016, In: Nature. 535, 7612, p. 376-381 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    A computational framework to integrate high-throughput "-omics" datasets for the identification of potential mechanistic links

    Pedersen, H. K., Forslund, S. K., Gudmundsdottir, V., Petersen, A. Ø., Hildebrand, F., Hyötyläinen, T., Nielsen, T., Hansen, Torben, Bork, P., Ehrlich, S. D., Brunak, Søren, Oresic, M., Pedersen, Oluf Borbye & Nielsen, H. B., 2018, In: Nature Protocols. 13, 12, p. 2781-2800 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    Outcome of childhood obesity

    Pedersen, D. C., Sørensen, Thorkild I.A. & Baker, J. L., 2018, Eating Disorders and Obesity in Children and Adolescents. Hebebrand, J. & Herpertz-Dahlmann, B. (eds.). 1 ed. St. Louis, Missouri: Elsevier, p. 165-169 5 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  95. Published

    Associations of childhood BMI and change in BMI from childhood to adulthood with risks of hypertensive disorders in pregnancy

    Pedersen, D. C., Bjerregaard, L. G., Nohr, E. A., Rasmussen, K. M. & Baker, J. L., 2020, In: American Journal of Clinical Nutrition. 112, 5, p. 1180-1187 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    Changes and correlations in height from 7 to 69 years of age across the birth years of 1930 to 1989

    Pedersen, D. C., Meyle, K. D., Ängquist, Lars, Andersen, Ingelise, Tjønneland, Anne, Linneberg, Allan René, Osler, Merete, Mortensen, Erik Lykke, Gyntelberg, F., Lund, Rikke, Aarestrup, J. & Baker, J. L., 2020, In: American Journal of Human Biology. 32, 4, e23378.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    Ethnic inequalities in overweight and obesity prevalence among copenhagen schoolchildren from 2002 to 2007

    Pedersen, D. C., Aarestrup, J., Pearson, S. & Baker, J. L., 1 Sep 2016, In: Obesity Facts. 9, 4, p. 284-295 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    The effect of an extreme and prolonged population bottleneck on patterns of deleterious variation: insights from the Greenlandic Inuit

    Pedersen, C. T., Lohmueller, K. E., Grarup, N., Bjerregaard, P., Hansen, Torben, Siegismund, Hans Redlef, Moltke, Ida & Albrechtsen, Anders, Feb 2017, In: Genetics. 205, 2, p. 787-801 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Overweight and obesity trends in Copenhagen schoolchildren from 2002 to 2007

    Pearson, S., Hansen, B., Sørensen, Thorkild I.A. & Baker, J. L., 1 Nov 2010, In: Acta Paediatrica. 99, 11, p. 1675-8 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Deficiency of cardiac Acyl-CoA synthetase-1 induces diastolic dysfunction, but pathologic hypertrophy is reversed by rapamycin

    Paul, D. S., Grevengoed, Trisha Jean, Pascual, F., Ellis, J. M., Willis, M. S. & Coleman, R. A., Jun 2014, In: B B A - Reviews on Cancer. 1841, 6, p. 880-7 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review