Novo Nordisk Foundation Center for Basic Metabolic Research

Metabolite ratios as potential biomarkers for type 2 diabetes: a DIRECT study

Molnos, S., Wahl, S., Haid, M., Eekhoff, E. M. W., Pool, R., Floegel, A., Deelen, J., Much, D., Prehn, C., Breier, M., Draisma, H. H., van Leeuwen, N., Simonis-Bik, A. M. C., Jonsson, A., Willemsen, G., Bernigau, W., Wang-Sattler, R., Suhre, K., Peters, A., Thorand, B. & 24 others, Herder, C., Rathmann, W., Roden, M., Gieger, C., Kramer, M. H. H., van Heemst, D., Pedersen, H. K., Gudmundsdottir, V., Schulze, M. B., Pischon, T., de Geus, E. J. C., Boeing, H., Boomsma, D. I., Ziegler, A. G., Slagboom, P. E., Hummel, S., Beekman, M., Grallert, H., Brunak, Søren, McCarthy, M. I., Gupta, R., Pearson, E. R., Adamski, J. & 't Hart, L. M., 2018, In: Diabetologia. 61, 1, p. 117-129 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Pre-diabetes is associated with attenuation rather than volume of epicardial adipose tissue on computed tomography

Molnar, D., Björnson, E., Larsson, M., Adiels, M., Gummesson, A., Bäckhed, F., Hjelmgren, O. & Bergström, G., 2023, In: Scientific Reports. 13, 1, 12 p., 1623.

Research output: Contribution to journal › Journal article › Research › peer-review

A hospital-based child and adolescent overweight and obesity treatment protocol transferred into a community healthcare setting

Mollerup, P. M., Gamborg, Michael Orland, Trier, C., Bøjsøe, C., Nielsen, T. R. H., Baker, J. L. & Holm, Jens-Christian, 2017, In: PLOS ONE. 12, 3, 17 p., e0173033.

Research output: Contribution to journal › Journal article › Research › peer-review

Quality of life improves in children and adolescents during a community-based overweight and obesity treatment

Mollerup, P. M., Nielsen, T. R. H., Bøjsøe, C., Kloppenborg, J. T., Baker, J. L. & Holm, Jens-Christian, Jun 2017, In: Quality of Life Research. 26, 6, p. 1597-1608

Research output: Contribution to journal › Journal article › Research › peer-review

Reductions in blood pressure during a community-based overweight and obesity treatment in children and adolescents with prehypertension and hypertension

Mollerup, P. M., Lausten-Thomsen, U., Fonvig, Cilius Esmann, Baker, J. L. & Holm, Jens-Christian, Oct 2017, In: Journal of Human Hypertension. 31, p. 640-646 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Imidazole propionate is increased in diabetes and associated with dietary patterns and altered microbial ecology

Molinaro, A., Bel Lassen, P., Henricsson, M., Wu, H., Adriouch, S., Belda, E., Chakaroun, R., Nielsen, T., Bergh, P-O., Rouault, C., Andre, S., Marquet, F., Andreelli, F., Salem, J-E., Assmann, K., Bastard, J-P., Forslund, S., Le Chatelier, E., Falony, G., Pons, N. & 26 others, Prifti, E., Quinquis, B., Roume, H., Vieira-Silva, S., Hansen, T. H., Pedersen, H. K., Lewinter, C., Sønderskov, N. B., Køber, Lars Valeur, Vestergaard, H., Hansen, Torben, Zucker, J., Galan, P., Dumas, M., Raes, J., Oppert, J., Letunic, I., Nielsen, J., Bork, P., Ehrlich, S. D., Stumvoll, M., Pedersen, Oluf Borbye, Aron-Wisneswky, J., Clement, K., Baeckhed, F. & MetaCardis Consortium, M. C., 2020, In: Nature Communications. 11, 1, 10 p., 5881.

Research output: Contribution to journal › Journal article › Research › peer-review

Hepatic expression of lipopolysaccharide- binding protein ( Lbp ) is induced by the gut microbiota through Myd88 and impairs glucose tolerance in mice independent of obesity

Molinaro, A., Koh, A., Wu, H., Schoeler, M., Faggi, M. I., Carreras, A., Hallen, A., Backhed, F. & Caesar, R., 2020, In: Molecular Metabolism. 37, 9 p., 100997.

Research output: Contribution to journal › Journal article › Research › peer-review

Liver-specific RORα deletion does not affect the metabolic susceptibility to western style diet feeding

Molinaro, A., Caesar, R., L'homme, L., Koh, A., Stahlman, M., Staels, B. & Backhed, F., 2019, In: Molecular Metabolism. 23, p. 82-87 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Microbially Produced Imidazole Propionate Is Associated With Heart Failure and Mortality

Molinaro, A., Nemet, I., Bel Lassen, P., Chakaroun, R., Nielsen, T., Aron-Wisnewsky, J., Bergh, P. O., Li, L., Henricsson, M., Køber, Lars Valeur, Isnard, R., Helft, G., Stumvoll, M., Pedersen, Oluf Borbye, Smith, J. G., Tang, W. H. W., Clément, K., Hazen, S. L., Bäckhed, F. & MetaCardis Consortium, M. C., 2023, In: JACC: Heart Failure. 11, 7, p. 810-821 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Host-microbiota interaction induces bi-phasic inflammation and glucose intolerance in mice

Molinaro, A., Caesar, R., Holm, L. M., Tremaroli, V., Cani, P. D. & Bäckhed, F., Nov 2017, In: Molecular Metabolism. 6, 11, p. 1371-1380 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Insulin-Driven PI3K-AKT Signaling in the Hepatocyte Is Mediated by Redundant PI3Kα and PI3Kβ Activities and Is Promoted by RAS

Molinaro, A., Becattini, B., Mazzoli, A., Bleve, A., Radici, L., Maxvall, I., Sopasakis, V. R., Molinaro, A., Bäckhed, F. & Solinas, G., 2019, In: Cell Metabolism. 29, 6, p. 1400-1409.e5

Research output: Contribution to journal › Journal article › Research › peer-review

Modulation of constitutive activity and signaling bias of the ghrelin receptor by conformational constraint in the second extracellular loop

Mokrosinski, J., Frimurer, Thomas Michael, Sivertsen, B., Schwartz, Thue W. & Holst, Birgitte, Sep 2012, In: Journal of Biological Chemistry. 287, p. 33488-33502 15 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Comparative analysis of sperm DNA methylation supports evolutionary acquired epigenetic plasticity for organ speciation

Moharrek, Farideh, Ingerslev, L. R., Altıntaş, Ali, Lundell, L., Hansen, Ann Normann, Small, Lewin Barkla, Workman, C. T. & Barrès, Romain, 2022, In: Epigenomics. 14, 21, p. 1305-1324 20 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Investigating the causal effect of maternal vitamin B12 and folate levels on offspring birthweight

Moen, G., Beaumont, R. N., Grarup, N., Sommer, C., Shields, B. M., Lawlor, D. A., Freathy, R. M., Evans, D. M. & Warrington, N. M., 2021, In: International Journal of Epidemiology. 50, 1, p. 179-189 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Amino acids differ in their capacity to stimulate GLP-1 release from the perfused rat small intestine and stimulate secretion by different sensing mechanisms

Modvig, Ida Marie, Kuhre, Rune Ehrenreich, Jepsen, Sara Lind, Xu, S., Engelstoft, M. S., Egerod, Kristoffer Lihme, Schwartz, Thue W., Ørskov, Cathrine, Rosenkilde, Mette & Holst, Jens Juul, 2021, In: American Journal of Physiology: Endocrinology and Metabolism. 320, p. E874-E885 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

_L-valine is a powerful stimulator of GLP-1 secretion in rodents and stimulates secretion through ATP-sensitive potassium channels and voltage-gated calcium channels

Modvig, Ida Marie, Smits, Mark, Galsgaard, Katrine Douglas, Hjørne, A. P., Drzazga, Anna Katarzyna, Rosenkilde, Mette & Holst, Jens Juul, 2024, In: Nutrition and Diabetes. 14, 11 p., 43.

Research output: Contribution to journal › Journal article › Research › peer-review

Secretin release after Roux-en-Y gastric bypass reveals a population of glucose-sensitive S cells in distal small intestine

Modvig, Ida Marie, Andersen, Daniel Bjørklund, Grunddal, Kaare Villum, Kuhre, Rune Ehrenreich, Martinussen, C., Christiansen, Charlotte Bayer, Ørskov, Cathrine, Larraufie, P., Kay, R. G., Reimann, F., Gribble, F. M., Hartmann, Bolette, Bojsen-Moller, K. N., Madsbad, Sten, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2020, In: International Journal of Obesity. 44, 9, p. 1859-1871

Research output: Contribution to journal › Journal article › Research › peer-review

Peptone-mediated glucagon-like peptide-1 secretion depends on intestinal absorption and activation of basolaterally located Calcium-Sensing Receptors

Modvig, Ida Marie, Kuhre, Rune Ehrenreich & Holst, Jens Juul, Apr 2019, In: Physiological Reports. 7, 8, 13 p., e14056.

Research output: Contribution to journal › Journal article › Research › peer-review

CCK-1 and CCK-2 receptor agonism do not stimulate GLP-1 and neurotensin secretion in the isolated perfused rat small intestine or GLP-1 and PYY secretion in the rat colon

Modvig, Ida Marie, Christiansen, Charlotte Bayer, Rehfeld, Jens Frederik, Holst, Jens Juul & Veedfald, Simon, 2020, In: Physiological Reports. 8, 2, 8 p., 14352.

Research output: Contribution to journal › Journal article › Research › peer-review

Plasma levels of glucagon but not GLP-1 are elevated in response to inflammation in humans

Modrzynska, J., Klein, C. F., Iversen, Kasper, Bundgård, Henning, Hartmann, Bolette, Mose, M., Rittig, N., Møller, N., Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2021, In: Endocrine Connections. 10, 2, p. 205-213 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Metabolic effects of Lactobacillus reuteri DSM 17938 in people with type 2 diabetes: A randomized controlled trial

Mobini, R., Tremaroli, V., Ståhlman, M., Karlsson, F., Levin, M., Ljungberg, M., Sohlin, M., Bertéus Forslund, H., Perkins, R., Bäckhed, G. F. & Jansson, P., Apr 2017, In: Diabetes, Obesity and Metabolism. 19, 4, p. 579-589 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

ARDD 2020: from aging mechanisms to interventions

Mkrtchyan, G. V., Abdelmohsen, K., Andreux, P., Bagdonaite, I., Barzilai, N., Brunak, S., Cabreiro, F., Cabo, R. D., Campisi, J., Cuervo, A. M., Demaria, M., Ewald, C. Y., Fang, E. F., Faragher, R., Ferrucci, L., Freund, A., Silva-García, C. G., Georgievskaya, A., Gladyshev, V. N., Glass, D. J. & 46 others, Gorbunova, V., Grey, A. D., He, W. W., Hoeijmakers, J., Hoffmann, Eva, Horvath, S., Houtkooper, R. H., Jensen, Majken Karoline, Jensen, M. B., Kane, A., Kassem, Moustapha Saad El-Deen, Keizer, P. D., Kennedy, B., Karsenty, G., Lamming, D. W., Lee, K. F., MacAulay, Nanna, Mamoshina, P., Mellon, J., Molenaars, M., Moskalev, A., Mund, Andreas, Niedernhofer, L., Osborne, Brenna, Pak, H. H., Parkhitko, A., Raimundo, N., Rando, T. A., Rasmussen, Lene Juel, Reis, C., Riedel, C. G., Franco-Romero, A., Schumacher, B., Sinclair, D. A., Suh, Y., Taub, P. R., Toiber, D., Treebak, Jonas Thue, Valenzano, D. R., Verdin, E., Vijg, J., Young, S., Zhang, L., Bakula, Daniela Janina, Zhavoronkov, A. & Scheibye-Knudsen, Morten, 2020, In: Aging. 12, 24, p. 24486-24503 18 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Elucidating the relationship between migraine risk and brain structure using genetic data

International Headache Genetics Consortium, I. H. G. C., 1 Sep 2022, In: Brain. 145, 9, p. 3214-3224 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Precision subclassification of type 2 diabetes: a systematic review

Misra, S., Wagner, R., Ozkan, B., Schön, M., Sevilla-Gonzalez, M., Prystupa, K., Wang, C. C., Kreienkamp, R. J., Cromer, S. J., Rooney, M. R., Duan, D., Thuesen, A. C. B., Wallace, A. S., Leong, A., Deutsch, A. J., Andersen, M. K., Billings, L. K., Eckel, R. H., Sheu, W. H-H., Hansen, T. & 8 others, Stefan, N., Goodarzi, M. O., Ray, D., Selvin, E., Florez, J. C., Meigs, J. B., Udler, M. S. & ADA/EASD PMDI, A. P., 2023, In: Communications Medicine. 3, 19 p., 138.

Research output: Contribution to journal › Journal article › Research › peer-review

RNA sequencing unravels novel L cell constituents and mechanisms of GLP-1 secretion in human gastric bypass-operated intestine

Miskelly, M. G., Lindqvist, A., Piccinin, E., Hamilton, A., Cowan, E., Nergård, B. J., Del Giudice, R., Ngara, M., Cataldo, L. R., Kryvokhyzha, D., Volkov, P., Engelking, L., Artner, I., Lagerstedt, J. O., Eliasson, L., Ahlqvist, E., Moschetta, A., Hedenbro, J. & Wierup, N., 2023, In: Diabetologia. 67, 2, p. 356-370

Research output: Contribution to journal › Journal article › Research › peer-review

Diminishing benefits of urban living for children and adolescents’ growth and development

Mishra, A., Zhou, B., Rodriguez-Martinez, A., Bixby, H., Baker, J. L., Afzal, S., Allin, K., Andersen, L. B., Ängquist, L., Jørgensen, M. B., Bjerregaard, P., Bojesen, S. E., Christensen, K., Damsgaard, C. T., Dantoft, T. M., Eliasen, M., Eriksen, L., Halkjær, J., Giwercman, A., Jørgensen, T. & 19 others, Kristensen, P. L., Lind, L., Linneberg, Allan René, Madsen, A. L., Michaelsen, Kim F., Møllehave, Line Tang, Mortensen, Erik Lykke, Nordestgaard, Børge, Osler, Merete, Overvad, K., Schmidt, I. M., Schnohr, P., Schramm, S., Sodemann, M., Sørensen, Thorkild I.A., Tjønneland, Anne, Tolstrup, J. S., Wang, Q. & NCD Risk Factor Collaboration (NCD-RisC), N. R. F. C. (., 2023, In: Nature. 615, 7954, p. 874-883 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Specific synbiotics in early life protect against diet-induced obesity in adult mice

Mischke, M., Arora, Tulika, Tims, S., Engels, E., Sommer, N., van Limpt, K., Baars, A., Oozeer, R., Oosting, A., Bäckhed, F. & Knol, J., 2018, In: Diabetes, Obesity and Metabolism. 20, 6, p. 1408-1418 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Reporting guidelines for human microbiome research: the STORMS checklist

Mirzayi, C., Renson, A., Furlanello, C., Sansone, S. A., Zohra, F., Elsafoury, S., Geistlinger, L., Kasselman, L. J., Eckenrode, K., van de Wijgert, J., Loughman, A., Marques, F. Z., MacIntyre, D. A., Arumugam, M., Azhar, R., Beghini, F., Bergstrom, K., Bhatt, A., Bisanz, J. E., Braun, J. & 32 others, Bravo, H. C., Buck, G. A., Bushman, F., Casero, D., Clarke, G., Collado, M. C., Cotter, P. D., Cryan, J. F., Demmer, R. T., Devkota, S., Elinav, E., Escobar, J. S., Fettweis, J., Finn, R. D., Fodor, A. A., Forslund, S., Franke, A., Furlanello, C., Gilbert, J., Grice, E., Haibe-Kains, B., Handley, S., Herd, P., Holmes, S., Jacobs, J. P., Karstens, L., Knight, R., Knights, D., Koren, O., Kwon, D. S., Genomic Standards Consortium, G. S. C. & Massive Analysis and Quality Control Society, M. A. A. Q. C. S., 2021, In: Nature Medicine. 27, 11, p. 1885-1892 8 p.

Research output: Contribution to journal › Review › Research › peer-review

Diverse repertoire of human adipocyte subtypes develops from transcriptionally distinct mesenchymal progenitor cells

Min, S. Y., Desai, A., Yang, Z., Sharma, A., DeSouza, T., Genga, R. M. J., Kucukural, A., Lifshitz, L. M., Nielsen, S., Schéele, Camilla Charlotte Nielsen, Maehr, R., Garber, M. & Corvera, S., 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 36, p. 17970-17979

Research output: Contribution to journal › Journal article › Research › peer-review

Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation

Min, J. L., Hemani, G., Hannon, E., Dekkers, K. F., Castillo-Fernandez, J., Luijk, R., Carnero-Montoro, E., Lawson, D. J., Burrows, K., Suderman, M., Bretherick, A. D., Richardson, T. G., Klughammer, J., Iotchkova, V., Sharp, G., Al Khleifat, A., Shatunov, A., Iacoangeli, A., McArdle, W. L., Ho, K. M. & 31 others, Kumar, A., Söderhäll, C., Soriano-Tárraga, C., Giralt-Steinhauer, E., Kazmi, N., Mason, D., McRae, A. F., Corcoran, D. L., Sugden, K., Kasela, S., Cardona, A., Day, F. R., Cugliari, G., Viberti, C., Guarrera, S., Lerro, M., Gupta, R., Bollepalli, S., Mandaviya, P., Zeng, Y., Clarke, T. K., Walker, R. M., Schmoll, V., Czamara, D., Ruiz-Arenas, C., Elliott, H. R., Nohr, E. A., Sørensen, Thorkild I.A., Hansen, Torben, Morgen, C. S. & BIOS Consortium, B. C., 2021, In: Nature Genetics. 53, 9, p. 1311-1321 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour

Mills, M. C., Tropf, F. C., Brazel, D. M., van Zuydam, N., Vaez, A., Agbessi, M., Ahsan, H., Alves, I., Andiappan, A. K., Arindrarto, W., Awadalla, P., Battle, A., Beutner, F., Jan Bonder, M., Boomsma, D. I., Christiansen, M. W., Claringbould, A., Deelen, P., Esko, T., Favé, M-J. & 33 others, Franke, L., Frayling, T., Gharib, S. A., Gibson, G., Heijmans, B. T., Hemani, G., Jansen, R., Kähönen, M., Kalnapenkis, A., Kasela, S., Kettunen, J., Kim, Y., Kirsten, H., Krohn, K., Kronberg, J., Kukushkina, V., Kutalik, Z., Lee, B., Lehtimäki, T., Loeffler, M., Marigorta, U. M., Mei, H., Milani, L., Montgomery, G. W., Müller-Nurasyid, M., Nauck, M., Nivard, M. G., Penninx, B. W. J. H., Møllegaard, Stine, Pers, Tune H, eQTLGen Consortium, E. C., BIOS Consortium, B. C. & Human Reproductive Behaviour Consortium, H. R. B. C., 2021, In: Nature Human Behaviour. 5, p. 1717-1730

Research output: Contribution to journal › Journal article › Research › peer-review

Structural changes at the myrtenol backbone reverse its positive allosteric potential into inhibitory GABA_A receptor modulation

Milanos, S., Kuenzel, K., Gilbert, D. F., Janzen, D., Sasi, M., Buettner, A., Frimurer, Thomas Michael & Villmann, C., 2018, In: Biological Chemistry. 399, 6, p. 549-563 15 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Recombinant human β-defensin 2 delivery improves smoking-induced lung neutrophilia and bacterial exacerbation

Milad, N., Pineault, M., Bouffard, G., Maranda-Robitaille, M., Lechasseur, A., Beaulieu, M. J., Aubin, S., Jensen, Benjamin Anderschou Holbech & Morissette, M. C., 2022, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 323, 1, p. L37-L47 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Type 2 diabetes is associated with increased circulating levels of 3-hydroxydecanoate activating GPR84 and neutrophil migration

Mikkelsen, R. B., Arora, Tulika, Trošt, K., Dmytriyeva, O., Jensen, Sune K. , Meijnikman, A. S., Olofsson, L. E., Lappa, D., Aydin, Ö., Nielsen, J., Gerdes, V., Moritz, Thomas, van de Laar, A., de Brauw, M., Nieuwdorp, M., Hjorth, Siv Annegrethe, Schwartz, Thue W. & Bäckhed, F., 2022, In: iScience. 25, 12, 29 p., 105683.

Research output: Contribution to journal › Journal article › Research › peer-review

Use of Antibiotics and Risk of Type 2 Diabetes: A Population-Based Case-Control Study

Mikkelsen, K. H., Knop, Filip Krag, Frost, M., Hallas, J. & Pottegård, A., 2015, In: Journal of Clinical Endocrinology and Metabolism. 100, 10, p. 3633-40 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Gut microbiota may have influence on glucose and lipid metabolism.

Mikkelsen, K. H., Nielsen, M. F., Tvede, M., Hansen, Torben, Pedersen, Oluf Borbye, Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, 11 Nov 2013, In: Ugeskrift for Laeger. 175, 46, p. 2785-2788 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Effect of antibiotics on gut microbiota, glucose metabolism and bodyweight regulation: a review of the literature

Mikkelsen, K. H., Allin, K. H. & Knop, Filip Krag, May 2016, In: Diabetes, Obesity and Metabolism. 18, 5, 444–453.

Research output: Contribution to journal › Review › Research › peer-review

No changes in levels of bone formation and resorption markers following a broad-spectrum antibiotic course

Mikkelsen, K. H., Vilsbøll, Tina, Holst, Jens Juul, Hartmann, Bolette, Knop, Filip Krag & Frost, M., 2018, In: BMC Endocrine Disorders. 18, 6 p., 60.

Research output: Contribution to journal › Journal article › Research › peer-review

Effect of Antibiotics on Gut Microbiota, Gut Hormones and Glucose Metabolism

Mikkelsen, K. H., Frost, M., Bahl, M. I., Licht, T. R., Jensen, U. S., Rosenberg, Jacob, Pedersen, Oluf Borbye, Hansen, Torben, Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, 12 Nov 2015, In: PLOS ONE. 10, 11, p. 1-14 e0142352.

Research output: Contribution to journal › Journal article › Research › peer-review

Nerve fibers in the rat posterior pituitary lobe contain Prosomatostatin (1-64)

Mikkelsen, J. D., Bersani, M., Holst, Jens Juul & Larsen, P. J., 1991, In: Neuroendocrinology. 54, p. 469-476

Research output: Contribution to journal › Journal article › Research › peer-review

The new donor vigilance system in Denmark reveals regional differences in adverse reactions supposedly caused by variation in the registration

Mikkelsen, Christina, Paarup, H. M., Bruun, M. T., Pedersen, L. Ø., Hasslund, S., Larsen, R., Aagaard, B. & Sørensen, B. S., 2022, In: Vox Sanguinis. 117, 3, p. 321-327

Research output: Contribution to journal › Journal article › Research › peer-review

A Danish national, multicentre evaluation of the new donor vigilance system among different staff groups

Mikkelsen, Christina, Paarup, H. M., Bruun, M. T., Pedersen, L. Ø., Hasslund, S., Larsen, R., Aagaard, B. & Sørensen, B. S., 2023, In: Vox Sanguinis. 118, 2, p. 121-127

Research output: Contribution to journal › Journal article › Research › peer-review

Prevalence of major depressive disorder in 51,658 otherwise healthy adult Danes: Sex differences in symptomatology and prediction of future anti-depressive medication

Mikkelsen, Christina, Larsen, M. A. H., Sørensen, E., Hansen, Thomas Folkmann, Mikkelsen, S., Erikstrup, C., Nielsen, K. R., Bruun, M. T., Hjalgrim, Henrik, Kessing, Lars Vedel, Werge, Thomas, Ullum, H., Ostrowski, Sisse Rye, Pedersen, Ole Birger Vesterager, Thørner, L. W. & Didriksen, Maria, 2022, In: Psychiatry Research. 318, 7 p., 114944.

Research output: Contribution to journal › Journal article › Research › peer-review

Emptying of the Gastric Substitute, Glucagon-like Peptide-1 (GLP-1), and Reactive hypoglycemia after Total Gastrectomy

Miholic, J., Ørskov, C., Holst, Jens Juul, Kotzerke, J. & Meyer, H. J., 1991, In: Digestive Diseases and Sciences. 36, no.10, p. 1361-1370

Research output: Contribution to journal › Journal article › Research › peer-review

Postprandial release of glucagon-like peptide-1, pancreatic glucagon, and insulin after esophageal resection

Miholic, J., Ørskov, C., Holst, Jens Juul, Kotzerke, J. & Pichlmayr, R., 1993, In: Digestion. 54, p. 73-78

Research output: Contribution to journal › Journal article › Research › peer-review

Glucagon-like peptide-1 (GLP-1), Entleerung des Magenersatzes und das Dumpingsyndrom nach Gastrektomie

Miholic, J., Ørskov, C., Holst, Jens Juul, Meyer, H. & Pichlmayr, R., 1991, In: Langerbecks Archiv für Chirurgie. (108. Kongress der Deutsch.Gesellsch.Chirurgie. Suppl.1991, p. 430-432

Research output: Contribution to journal › Journal article › Research › peer-review

Human pancreatic islet three-dimensional chromatin architecture provides insights into the genetics of type 2 diabetes

Miguel-Escalada, I., Bonàs-Guarch, S., Cebola, I., Ponsa-Cobas, J., Mendieta-Esteban, J., Atla, G., Javierre, B. M., Rolando, D. M. Y., Farabella, I., Morgan, C. C., García-Hurtado, J., Beucher, A., Morán, I., Pasquali, L., Ramos-Rodríguez, M., Appel, E. V. R., Linneberg, A., Gjesing, A. P., Witte, D. R., Pedersen, O. & 16 others, Grarup, N., Ravassard, P., Torrents, D., Mercader, J. M., Piemonti, L., Berney, T., de Koning, E. J. P., Kerr-Conte, J., Pattou, F., Fedko, I. O., Groop, L., Prokopenko, I., Hansen, Torben, Marti-Renom, M. A., Fraser, P. & Ferrer, J., 2019, In: Nature Genetics. 51, 7, p. 1137-1148

Research output: Contribution to journal › Journal article › Research › peer-review

Dipeptidyl peptidase-4 inhibitors administered in combination with metformin result in an additive increase in the plasma concentration of active GLP-1

Migoya, E. M., Bergeron, R., Miller, J. L., Snyder, R. N. K., Tanen, M., Hilliard, D., Weiss, B., Larson, P., Gutierrez, M., Jiang, G., Liu, F., Pryor, K. A., Yao, J., Zhu, L., Holst, J. J., Deacon, C., Herman, G., Thornberry, N., Amatruda, J., Williams-Herman, D. & 2 others, Wagner, J. A. & SinhaRoy, R., 1 Dec 2010, In: Clinical Pharmacology and Therapeutics. 88, 6, p. 801-8 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Novel synthetic route to the C-nucleoside, 2-deoxy benzamide riboside

Midtkandal, R. R., Redpath, P., Trammell, Sam, MacDonald, S. J. F., Brenner, C. & Migaud, M. E., 15 Aug 2012, In: Bioorganic and Medicinal Chemistry Letters. 22, 16, p. 5204-5207 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia: design, results and future prospects

Middeldorp, C. M., Mahajan, A., Horikoshi, M., Robertson, N. R., Beaumont, R. N., Bradfield, J. P., Bustamante, M., Cousminer, D. L., Day, F. R., De Silva, N. M., Guxens, M., Mook-Kanamori, D. O., St Pourcain, B., Warrington, N. M., Adair, L. S., Ahlqvist, E., Ahluwalia, T. S., Almgren, P., Ang, W., Atalay, M. & 463 others, Auvinen, J., Bartels, M., Beckmann, J. S., Bilbao, J. R., Bond, T., Borja, J. B., Cavadino, A., Charoen, P., Chen, Z., Coin, L., Cooper, C., Curtin, J. A., Custovic, A., Das, S., Davies, G. E., Dedoussis, G. V., Duijts, L., Eastwood, P. R., Eliasen, A. U., Elliott, P., Eriksson, J. G., Estivill, X., Fadista, J., Fedko, I. O., Frayling, T. M., Gaillard, R., Gauderman, W. J., Geller, F., Gilliland, F., Gilsanz, V., Granell, R., Grarup, N., Groop, L., Hadley, D., Hakonarson, H., Hansen, Torben, Hartman, C. A., Hattersley, A. T., Hayes, M. G., Hebebrand, J., Heinrich, J., Helgeland, O., Henders, A. K., Henderson, J., Henriksen, T. B., Hirschhorn, J. N., Hivert, M., Hocher, B., Holloway, J. W., Holt, P., Hottenga, J., Hypponen, E., Iniguez, C., Johansson, S., Jugessur, A., Kahonen, M., Kalkwarf, H. J., Kaprio, J., Karhunen, V., Kemp, J. P., Kerkhof, M., Koppelman, G. H., Korner, A., Kotecha, S., Kreiner-Moller, E., Kulohoma, B., Kumar, A., Kutalik, Z., Lahti, J., Lappe, J. M., Larsson, H., Lehtimaki, T., Lewin, A. M., Li, J., Lichtenstein, P., Lindgren, C. M., Lindi, V., Linneberg, Allan René, Liu, X., Liu, J., Lowe, W. L. ,. J., Lundstrom, S., Lyytikainen, L., Ma, R. C. W., Mace, A., Magi, R., Magnus, P., Mamun, A. A., Mannikko, M., Martin, N. G., Mbarek, H., McCarthy, N. S., Medland, S. E., Melbye, M., Melen, E., Mohlke, K. L., Monnereau, C., Morgen, C. S., Morris, A. P., Murray, J. C., Myhre, R., Najman, J. M., Nivard, M. G., Nohr, E. A., Nolte, I. M., Ntalla, I., O'Reilly, P., Oberfield, S. E., Oken, E., Oldehinkel, A. J., Pahkala, K., Palviainen, T., Panoutsopoulou, K., Pedersen, Oluf Borbye, Pennell, C. E., Pershagen, G., Pitkanen, N., Plomin, R., Power, C., Prasad, R. B., Prokopenko, I., Pulkkinen, L., Raikkonen, K., Raitakari, O. T., Reynolds, R. M., Richmond, R. C., Rivadeneira, F., Rodriguez, A., Rose, R. J., Salem, R., Santa-Marina, L., Saw, S., Schnurr, T. M., Scott, J. G., Selzam, S., Shepherd, J. A., Simpson, A., Skotte, L., Sleiman, P. M. A., Snieder, H., Sørensen, Thorkild I.A., Standl, M., Steegers, E. A. P., Strachan, D. P., Straker, L., Strandberg, T., Taylor, M., Teo, Y., Thiering, E., Torrent, M., Tyrrell, J., Uitterlinden, A. G., van Beijsterveldt, T., van der Most, P. J., van Duijn, C. M., Viikari, J., Vilor-Tejedor, N., Vogelezang, S., Vonk, J. M., Vrijkotte, T. G. M., Vuoksimaa, E., Wang, C. A., Watkins, W. J., Wichmann, H., Willemsen, G., Williams, G. M., Wilson, J. F., Wray, N. R., Xu, S., Xu, C., Yaghootkar, H., Yi, L., Zafarmand, M. H., Zeggini, E., Zemel, B. S., Hinney, A., Lakka, T. A., Whitehouse, A. J. O., Sunyer, J., Widen, E. E., Feenstra, B., Sebert, S., Jacobsson, B., Njolstad, P. R., Stoltenberg, C., Smith, G. D., Lawlor, D. A., Paternoster, L., Timpson, N. J., Ong, K. K., Bisgaard, H., Bønnelykke, Klaus, Jaddoe, V. W. V., Tiemeier, H., Jarvelin, M., Evans, D. M., Perry, J. R. B., Grant, S. F. A., Boomsma, D. I., Freathy, R. M., McCarthy, M. I., Adair, L. S., Ahlqvist, E., Ahluwalia, Tarun Veer Singh, Almgren, P., Ang, W., Atalay, M., Beaumont, R. N., Beckmann, J. S., Bisgaard, H., Bond, T., Bønnelykke, Klaus, Boomsma, D. I., Borja, J. B., Bradfield, J. P., Bustamante, M., Cavadino, A., Charoen, P., Coin, L., Cooper, C., Cousminer, D. L., Curtin, J. A., Custovic, A., Das, S., Day, F. R., De Silva, N. M., Dedoussis, G. V., Elliott, P., Eriksson, J. G., Evans, D. M., Fadista, J., Feenstra, B., Felix, J. F., Frayling, T. M., Freathy, R. M., Gaillard, R., Geller, F., Gilsanz, V., Grant, S. F. A., Grarup, N., Groop, L., Guxens, M., Hadley, D., Hakonarson, H., Hansen, Torben, Hattersley, A. T., Hayes, M. G., Hebebrand, J., Heinrich, J., Helgeland, O., Henriksen, T. B., Hinney, A., Hirschhorn, J. N., Hivert, M., Hocher, B., Holloway, J. W., Horikoshi, M., Hottenga, J., Hypponen, E., Jacobsson, B., Jaddoe, V. W. V., Jarvelin, M., Johansson, S., Kalkwarf, H. J., Kerkhof, M., Korner, A., Kotecha, S., Kreiner-Moller, E., Kulohoma, B., Kutalik, Z., Lakka, T. A., Lappe, J. M., Lawlor, D. A., Lehtimaki, T., Lewin, A. M., Lindgren, C. M., Lindi, V., Linneberg, Allan René, Liu, X., Liu, J., Lowe, W. L. ,. J., Ma, R. C. W., Mace, A., Magi, R., Magnus, P., Mahajan, A., McCarthy, N. S., McCarthy, M. I., Melbye, M., Mohlke, K. L., Monnereau, C., Mook-Kanamori, D. O., Morgen, C. S., Morris, A. P., Murray, J. C., Myhre, R., Njolstad, P. R., Nohr, E. A., Ntalla, I., O'Reilly, P., Oberfield, S. E., Oken, E., Ong, K. K., Panoutsopoulou, K., Pedersen, Oluf Borbye, Pennell, C. E., Perry, J. R. B., Pitkanen, N., St Pourcain, B., Power, C., Prasad, R. B., Prokopenko, I., Raitakari, O. T., Reynolds, R. M., Richmond, R. C., Rodriguez, A., Salem, R., Saw, S., Schnurr, T. M., Sebert, S., Shepherd, J. A., Simpson, A., Skotte, L., Sørensen, Thorkild I.A., Standl, M., Steegers, E. A. P., Strachan, D. P., Sunyer, J., Taylor, M., Teo, Y., Thiering, E., Timpson, N. J., Tyrrell, J., Uitterlinden, A. G., van Duijn, C. M., Vogelezang, S., Vrijkotte, T. G. M., Wang, C. A., Warrington, N. M., Watkins, W. J., Wichmann, H., Widen, E. E., Willemsen, G., Wilson, J. F., Yaghootkar, H., Zafarmand, M. H., Zeggini, E., Zemel, B. S., Ahluwalia, T. S., Auvinen, J., Bartels, M., Bilbao, J. R., Bisgaard, H., Bønnelykke, Klaus, Boomsma, D. I., Bradfield, J. P., Bustamante, M., Chen, Z., Curtin, J. A., Custovic, A., Smith, G. D., Davies, G. E., Duijts, L., Eastwood, P. R., Eliasen, A. U., Estivill, X., Evans, D. M., Fedko, I. O., Felix, J. F., Gauderman, W. J., Gilliland, F., Granell, R., Grant, S. F. A., Guxens, M., Hakonarson, H., Hartman, C. A., Heinrich, J., Henders, A. K., Henderson, J., Holt, P., Hottenga, J., Hypponen, E., Iniguez, C., Jacobsson, B., Jaddoe, V. W. V., Jarvelin, M., Jugessur, A., Kahonen, M., Kaprio, J., Karhunen, V., Kemp, J. P., Koppelman, G. H., Kumar, A., Lahti, J., Larsson, Henrik Bo Wiberg, Lawlor, D. A., Lehtimaki, T., Li, J., Lichtenstein, P., Lundstrom, S., Lyytikainen, L., Magnus, P., Mamun, A. A., Mannikko, M., Martin, N. G., Mbarek, H., Medland, S. E., Melen, E., Middeldorp, C. M., Najman, J. M., Nivard, M. G., Nolte, I. M., Oldehinkel, A. J., Pahkala, K., Palviainen, T., Paternoster, L., Pennell, C. E., Pershagen, G., Pitkanen, N., Plomin, R., St Pourcain, B., Power, C., Pulkkinen, L., Raikkonen, K., Raitakari, O. T., Richmond, R. C., Rivadeneira, F., Rose, R. J., Santa-Marina, L., Scott, J. G., Sebert, S., Selzam, S., Simpson, A., Sleiman, P. M. A., Snieder, H., Standl, M., Stoltenberg, C., Strachan, D. P., Straker, L., Strandberg, T., Sunyer, J., Thiering, E., Tiemeier, H., Timpson, N. J., Torrent, M., Uitterlinden, A. G., van Beijsterveldt, T., van der Most, P. J., van Duijn, C. M., Viikari, J., Vilor-Tejedor, N., Vonk, J. M., Vrijkotte, T. G. M., Vuoksimaa, E., Wang, C. A., Whitehouse, A. J. O., Willemsen, G., Williams, G. M., Wray, N. R., Xu, S., Xu, C., Yi, L. & Zafarmand, M. H., 2019, In: European Journal of Epidemiology. 34, 3, p. 279-300 22 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Insulin stimulation regulates AS160 and TBC1D1 phosphorylation sites in human skeletal muscle

Middelbeek, R. J. W., Chambers, M. A., Tantiwong, P., Treebak, Jonas Thue, An, D., Hirshman, M. F., Musi, N. & Goodyear, L. J., Jun 2013, In: Nutrition and Diabetes. 3, 74, p. e74

Research output: Contribution to journal › Journal article › Research › peer-review

Structural and functional development of small intestine in intrauterine growth retarded porcine offspring born to gilts fed diets with differing protein ratios throughout pregnancy

Mickiewicz, M., Zabielski, R., Grenier, B., Le Normand, L., Savary, G., Holst, Jens Juul, Oswald, I. P., Metges, C. C. & Guilloteau, P., 2012, In: Journal of Physiology and Pharmacology. 63, 3, p. 225-39 15 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Endocrine and Metabolic Insights from Pancreatic Surgery

Mezza, T., Cefalo, C. M. A., Cinti, F., Quero, G., Pontecorvi, A., Alfieri, S., Holst, Jens Juul & Giaccari, A., Oct 2020, In: Trends in Endocrinology and Metabolism. 31, 10, p. 760-772

Research output: Contribution to journal › Review › Research › peer-review

Bile Modulates Secretion of Incretins and Insulin: A Study of Human Extrahepatic Cholestasis

Mezza, T., Moffa, S., Ferraro, P. M., Quero, G., Capece, U., Carfi, A., Cefalo, C. M. A., Cinti, F., Sorice, G. P., Impronta, F., Mari, A., Pontecorvi, A., Alfieri, S., Holst, Jens Juul & Giaccari, A., 2019, In: Journal of Clinical Endocrinology & Metabolism. 104, 7, p. 2685-2694

Research output: Contribution to journal › Journal article › Research › peer-review

Insulin resistance alters islet morphology in nondiabetic humans

Mezza, T., Muscogiuri, G., Sorice, G. P., Clemente, G., Hu, J., Pontecorvi, A., Holst, Jens Juul, Giaccari, A. & Kulkarni, R. N., Mar 2014, In: Diabetes. 63, 3, p. 994-1007 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Associations between childhood height and morphologically different variants of melanoma in adulthood

Meyle, K. D., Gamborg, M. O., Hølmich, Lisbet Rosenkrantz & Baker, J. L., Nov 2016, In: European journal of cancer (Oxford, England : 1990). 67, p. 99-105 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Childhood Body Size and the Risk of Malignant Melanoma in Adulthood

Meyle, K. D., Gamborg, Michael Orland, Sørensen, Thorkild I.A. & Baker, J. L., 15 Apr 2017, In: American Journal of Epidemiology. 185, 8, p. 673-680 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Effect of the natural sweetener xylitol on gut hormone secretion and gastric emptying in humans: A pilot dose-ranging study

Meyer-Gerspach, A. C., Drewe, J., Verbeure, W., Le Roux, C. W., Dellatorre-Teixeira, L., Rehfeld, Jens Frederik, Holst, Jens Juul, Hartmann, Bolette, Tack, J., Peterli, R., Beglinger, C. & Wölnerhanssen, B. K., 2021, In: Nutrients. 13, 1, 21 p., 174.

Research output: Contribution to journal › Journal article › Research › peer-review

Insulin gene mutations resulting in early-onset diabetes: marked differences in clinical presentation, metabolic status, and pathogenic effect through endoplasmic reticulum retention

Meur, G., Simon, A., Harun, N., Virally, M., Dechaume, A., Bonnefond, A., Fetita, S., Tarasov, A. I., Guillausseau, P., Boesgaard, T. W., Pedersen, Oluf Borbye, Hansen, T., Polak, M., Gautier, J., Froguel, P., Rutter, G. A. & Vaxillaire, M., 2009, In: Diabetes. 59, 3, p. 653-61 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The Arg82Cys Polymorphism of the Protein Nepmucin Implies a Role in HDL Metabolism

Metz, Sophia, Krarup, N. T., Bryrup, T., Støy, J., Andersson, E. A., Christoffersen, Christina, Neville, M. J., Christiansen, Malene Revsbech, Jonsson, Anna Elisabet, Witte, D. R., Kampmann, U., Nielsen, L. B., Jørgensen, Niklas Rye, Karpe, F., Grarup, N., Pedersen, Oluf Borbye, Kilpeläinen, Tuomas O. & Hansen, Torben, 2022, In: Journal of the Endocrine Society. 6, 5, 10 p., bvac034.

Research output: Contribution to journal › Journal article › Research › peer-review

Genetic variation, adipokines, and cardiometabolic disease

Metz, Sophia, Huang, L. O. & Kilpeläinen, Tuomas O., 2020, In: Current Opinion in Pharmacology. 52, p. 33-39 7 p.

Research output: Contribution to journal › Review › Research › peer-review

From man to mouse: The discovery and validation of CYR61 as a regulator of body composition

Metz, Sophia, Grevengoed, Trisha Jean, Kilpeläinen, Tuomas O. & Gillum, M. P., 2020, In: European Journal of Human Genetics. 28, SUPPL 1, p. 741-742 1 p.

Research output: Contribution to journal › Conference abstract in journal › Research

Effects of isomaltulose and high amounts of PUFAs together with elevated physical activity on subjects with a moderate metabolic risk profile before and after a 6-weeks randomized lifestyle intervention trial

Metz, Sophia, Kabisch, S. & Pfeiffer, A. F. H., May 2017, In: Diabetologie und Stoffwechsel. 12, S 01, p. S1-S84

Research output: Contribution to journal › Conference abstract in journal › Research

Molecular-scale simulation of electroluminescence in a multilayer white organic light-emitting diode

Mesta, M., Carvelli, M., de Vries, R. J., van Eersel, H., van der Holst, J. J. M., Schober, M., Furno, M., Lüssem, B., Leo, K., Loebl, P., Coehoorn, R., Bobbert, P. A. & Holst, Jens Juul, Jul 2013, In: Nature Materials. 12, 7, p. 652-8 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Neuropeptide Y (NPY) and vasoactive intestinal polypeptide (VIP), but not galanin, are autonomic cotransmitters in the porcine pancreas

Messell, T., Dunning, B. E., Sheikh, S. & Holst, Jens Juul, 1991, In: International Journal of Gastrointestinal Cancer. 10, p. 133-141

Research output: Contribution to journal › Journal article › Research › peer-review

Extrinsic control of the release of galanin and VIP from intrinsic nerves of isolated, perfused, porcine ileum

Messell, T., Harling, H., Poulsen, Steen Seier, Bersani, M. & Holst, Jens Juul, 9 Apr 1992, In: Regulatory Peptides. 38, 3, p. 179-98 20 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Extrinsic control of the release of galanin and VIP from intrinsic nerves of isolated, perfused porcine ileum

Messel, T., Harling, H., Poulsen, S. S., Bersani, M. & Holst, Jens Juul, 1992, In: Regulatory Peptides. 38, p. 179-198

Research output: Contribution to journal › Journal article › Research › peer-review

Genetic analysis of dietary intake identifies new loci and functional links with metabolic traits

Merino, J., Dashti, H. S., Sarnowski, C., Lane, J. M., Todorov, Petar Vladimirov, Udler, M. S., Song, Y., Wang, H., Kim, J., Tucker, C., Campbell, J., Tanaka, T., Chu, A. Y., Tsai, L., Pers, Tune H, Chasman, D., Rutter, M. K., Dupuis, J., Florez, J. C. & Saxena, R., 2022, In: Nature Human Behaviour. 6, p. 155-163 17 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genetic predisposition to macronutrient preference and workplace food choices

Merino, Jordi, Dashti, H. S., Levy, D. E., Del Rocío Sevilla-González, M., Hivert, M. F., Porneala, B. C., Saxena, R. & Thorndike, A. N., 2023, In: Molecular Psychiatry. 28, 9, p. 2606–2611

Research output: Contribution to journal › Review › Research › peer-review

Quality of dietary fat and genetic risk of type 2 diabetes: individual participant data meta-analysis

Merino, J., Guasch-Ferré, M., Ellervik, C., Dashti, H. S., Sharp, S. J., Wu, P., Overvad, K., Sarnowski, C., Kuokkanen, M., Lemaitre, R. N., Justice, A. E., Ericson, U., Braun, K. V. E., Mahendran, Y., Frazier-Wood, A. C., Sun, D., Chu, A. Y., Tanaka, T., Luan, J., Hong, J. & 48 others, Tjønneland, Anne, Ding, M., Lundqvist, A., Mukamal, K., Rohde, R., Schulz, C., Franco, O. H., Grarup, N., Chen, Y. I., Bazzano, L., Franks, P. W., Buring, J. E., Langenberg, C., Liu, C., Hansen, Torben, Jensen, Majken Karoline, Sääksjärvi, K., Psaty, B. M., Young, K. L., Hindy, G., Sandholt, C. H., Ridker, P. M., Ordovas, J. M., Meigs, J. B., Pedersen, Oluf Borbye, Kraft, P., Perola, M., North, K. E., Orho-Melander, M., Voortman, T., Toft, Ulla Marie Nørgaard, Rotter, J. I., Qi, L., Forouhi, N. G., Mozaffarian, D., Sørensen, Thorkild I.A., Stampfer, M. J., Männistö, S., Selvin, E., Imamura, F., Salomaa, V., Hu, F. B., Wareham, N. J., Dupuis, J., Smith, C. E., Kilpeläinen, Tuomas O., Chasman, D. I. & Florez, J. C., 2019, In: BMJ (Clinical research ed.). 366, p. l4292

Research output: Contribution to journal › Journal article › Research › peer-review

Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium

Dashti, H. S., Hansen, Torben, Astrup, A., Pedersen, Oluf Borbye, Sørensen, Thorkild I.A. & Cohorts for Heart and Aging Research in Genetic Epidemiology Consortium, C. F. H. A. A. R. I. G. E. C., 2019, In: Molecular Psychiatry. 24, p. 1920–1932

Research output: Contribution to journal › Journal article › Research › peer-review

Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age

Merid, S. K., Novoloaca, A., Sharp, G. C., Kupers, L. K., Kho, A. T., Roy, R., Gao, L., Annesi-Maesano, I., Jain, P., Plusquin, M., Kogevinas, M., Allard, C., Vehmeijer, F. O., Kazmi, N., Salas, L. A., Rezwan, F. I., Zhang, H., Sebert, S., Czamara, D., Rifas-Shiman, S. L. & 73 others, Melton, P. E., Lawlor, D. A., Pershagen, G., Breton, C. V., Huen, K., Baiz, N., Gagliardi, L., Nawrot, T. S., Corpeleijn, E., Perron, P., Duijts, L., Nohr, E. A., Bustamante, M., Ewart, S. L., Karmaus, W., Zhao, S., Page, C. M., Herceg, Z., Jarvelin, M., Lahti, J., Baccarelli, A. A., Anderson, D., Kachroo, P., Relton, C. L., Bergstrom, A., Eskenazi, B., Soomro, M. H., Vineis, P., Snieder, H., Bouchard, L., Jaddoe, V. W., Sørensen, Thorkild I.A., Vrijheid, M., Arshad, S. H., Holloway, J. W., Haberg, S. E., Magnus, P., Dwyer, T., Binder, E. B., DeMeo, D. L., Vonk, J. M., Newnham, J., Tantisira, K. G., Kull, I., Wiemels, J. L., Heude, B., Sunyer, J., Nystad, W., Munthe-Kaas, M. C., Raikkonen, K., Oken, E., Huang, R., Weiss, S. T., Anto, J. M., Bousquet, J., Kumar, A., Soderhall, C., Almqvist, C., Cardenas, A., Gruzieva, O., Xu, C., Reese, S. E., Kere, J., Brodin, P., Solomon, O., Wielscher, M., Holland, N., Ghantous, A., Hivert, M., Felix, J. F., Koppelman, G. H., London, S. J. & Melen, E., 2 Mar 2020, In: Genome Medicine. 12, 1, 17 p., 25.

Research output: Contribution to journal › Journal article › Research › peer-review

GIP does not potentiate the antidiabetic effects of GLP-1 in hyperglycemic patients with type 2 diabetes

Mentis, N., Vardarli, I., Köthe, L. D., Holst, Jens Juul, Deacon, Carolyn F., Theodorakis, M., Meier, J. J. & Nauck, M. A., 2011, In: Diabetes. 60, 4, p. 1270-1276 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Near-normalization of glycaemic control with glucagon-like peptide-1 receptor agonist treatment combined with exercise in patients with type 2 diabetes

Mensberg, P., Nyby, S., Jørgensen, P. G., Storgaard, H., Jensen, M. T., Sivertsen, J., Holst, Jens Juul, Kiens, Bente, Richter, Erik A., Knop, Filip Krag & Vilsbøll, Tina, 2017, In: Diabetes, Obesity and Metabolism. 19, 2, p. 172-180 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Loss of inverse relationship between pulsatile insulin and glucagon secretion in patients with type 2 diabetes

Menge, B. A., Grüber, L., Jørgensen, S. M., Deacon, Carolyn F., Schmidt, W. E., Veldhuis, J. D., Holst, Jens Juul & Meier, J. J., Aug 2011, In: Diabetes. 60, 8, p. 2160-2168 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Multi-ancestry genome-wide association study of major depression aids locus discovery, fine mapping, gene prioritization and causal inference

Meng, X., Navoly, G., Giannakopoulou, O., Levey, D. F., Koller, D., Pathak, G. A., Koen, N., Lin, K., Adams, M. J., Rentería, M. E., Feng, Y., Gaziano, J. M., Stein, D. J., Zar, H. J., Campbell, M. L., van Heel, D. A., Trivedi, B., Finer, S., McQuillin, A., Bass, N. & 58 others, Chundru, V. K., Martin, H. C., Huang, Q. Q., Valkovskaya, M., Chu, C. Y., Kanjira, S., Kuo, P. H., Chen, H. C., Tsai, S. J., Liu, Y. L., Kendler, K. S., Peterson, R. E., Cai, N., Fang, Y., Sen, S., Scott, L. J., Burmeister, M., Loos, Ruth, Preuss, M. H., Actkins, K. E. V., Davis, L. K., Uddin, M., Wani, A. H., Wildman, D. E., Aiello, A. E., Ursano, R. J., Kessler, R. C., Kanai, M., Okada, Y., Sakaue, S., Rabinowitz, J. A., Maher, B. S., Uhl, G., Eaton, W., Cruz-Fuentes, C. S., Martinez-Levy, G. A., Campos, A. I., Millwood, I. Y., Chen, Z., Li, L., Wassertheil-Smoller, S., Jiang, Y., Tian, C., Martin, N. G., Mitchell, B. L., Byrne, E. M., Awasthi, S., Coleman, J. R. I., Ripke, S., Sofer, T., Walters, R. G., McIntosh, A. M., Polimanti, R., Dunn, E. C., Stein, M. B., Gelernter, J., Lewis, C. M. & Kuchenbaecker, K., 2024, In: Nature Genetics. 56, 2, p. 222–233

Research output: Contribution to journal › Journal article › Research › peer-review

Body mass index in young men and risk of inflammatory bowel disease through adult life: A population-based Danish cohort study

Mendell, M. A., Jensen, C. B., Sørensen, Thorkild I.A., Ängquist, Lars & Jess, T., 2019, In: Scientific Reports. 9, 9 p., 6360.

Research output: Contribution to journal › Journal article › Research › peer-review

Translating biased signaling in the ghrelin receptor system into differential in vivo functions

Mende, F., Johnsen, Cecilie Hundahl, Plouffe, B., Skov, Louise Julie, Sivertsen, B., Madsen, A. N., Lückmann, Michael, Diep, T. A., Offermanns, S., Frimurer, Thomas Michael, Bouvier, M. & Holst, Birgitte, 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 43, p. E10255-E10264 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Assessment of metagenomic assembly using simulated next generation sequencing data

Mende, D. R., Waller, A. S., Sunagawa, S., Järvelin, A. I., Chan, M. M., Arumugam, Mani, Raes, J. & Bork, P., 2012, In: P L o S One. 7, 2, p. e31386

Research output: Contribution to journal › Journal article › Research › peer-review

Childhood growth and risk of inflammatory bowel disease: a population-based study of 317,030 children

Mendall, M., Jensen, C. B., Ängquist, Lars, Baker, J. L. & Jess, T., 2019, In: Scandinavian Journal of Gastroenterology. 54, 7, p. 863-868

Research output: Contribution to journal › Journal article › Research › peer-review

Trigonelline is an NAD⁺ precursor that improves muscle function during ageing and is reduced in human sarcopenia

Membrez, M., Migliavacca, E., Christen, S., Yaku, K., Trieu, J., Lee, A. K., Morandini, F., Giner, M. P., Stiner, J., Makarov, M. V., Garratt, E. S., Vasiloglou, M. F., Chanvillard, L., Dalbram, E., Ehrlich, A. M., Sanchez-Garcia, J. L., Canto, C., Karagounis, L. G., Treebak, J. T., Migaud, M. E. & 15 others, Heshmat, R., Razi, F., Karnani, N., Ostovar, A., Farzadfar, F., Tay, S. K. H., Sanders, M. J., Lillycrop, K. A., Godfrey, K. M., Nakagawa, T., Moco, S., Koopman, R., Lynch, G. S., Sorrentino, V. & Feige, J. N., 2024, In: Nature Metabolism. 6, 3, p. 433–447

Research output: Contribution to journal › Letter › Research › peer-review

A metabolomic study of Gomphrena agrestis in Brazilian Cerrado suggests drought-adaptive strategies on metabolism

Melo, G. A., Abreu, I. N., de Oliveira, M. B., Budzinski, I. G. F., Silva, L. V., Silva Pimenta, M. A. & Moritz, Thomas, 2021, In: Scientific Reports. 11, 13 p., 12933.

Research output: Contribution to journal › Journal article › Research › peer-review

Leg length, sitting height and postmenopausal breast cancer risk

Mellemkjær, L., Christensen, J., Frederiksen, K., Baker, J. L., Olsen, A., Sørensen, Thorkild I.A. & Tjønneland, A., 2012, In: B J C. 107, 1, p. 165-8 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Rare Heterozygous Loss-of-Function Variants in the Human GLP-1 Receptor Are Not Associated With Cardiometabolic Phenotypes

Melchiorsen, Josefine Ulrikke, Sørensen, Kimmie Vestergaard, Bork-Jensen, J., Kizilkaya, Hüsün Sheyma, Gasbjerg, Lærke Smidt, Hauser, Alexander Sebastian, Rungby, Jørgen, Sørensen, H. T., Vaag, Allan, Nielsen, J. S., Pedersen, Oluf Borbye, Linneberg, Allan René, Hartmann, Bolette, Gjesing, A. P., Holst, Jens Juul, Hansen, Torben, Rosenkilde, Mette & Grarup, N., 2023, In: Journal of Clinical Endocrinology and Metabolism. 108, 11, p. 2821–2833 38 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Short‐chain fatty acids and gut microbiota in multiple sclerosis

Melbye, P., Olsson, A., Hansen, T. H., Søndergaard, H. B. & Oturai, A. B., 2019, In: Acta Neurologica Scandinavica. 139, 3, p. 208-219

Research output: Contribution to journal › Review › Research › peer-review

Hyperinsulinemia Is Highly Associated With Markers of Hepatocytic Senescence in Two Independent Cohorts

Meijnikman, A. S., van Olden, C. C., Aydin, Ö., Herrema, H., Kaminska, D., Lappa, D., Männistö, V., Tremaroli, V., Olofsson, L. E., de Brauw, M., van de Laar, A., Verheij, J., Gerdes, V. E. A., Schwartz, T. W., Nielsen, J., Bäckhed, F., Pajukanta, P., Pihlajamäki, J., Tchkonia, T., Kirkland, J. L. & 3 others, Kuipers, F., Nieuwdorp, M. & Groen, A. K., 2022, In: Diabetes. 71, 9, p. 1929-1936 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Microbiome-derived ethanol in nonalcoholic fatty liver disease

Meijnikman, A. S., Davids, M., Herrema, H., Aydin, O., Tremaroli, V., Rios-Morales, M., Levels, H., Bruin, S., de Brauw, M., Verheij, J., Kemper, M., Holleboom, A. G., Tushuizen, M. E., Schwartz, T. W., Nielsen, J., Brandjes, D., Dirinck, E., Weyler, J., Verrijken, A., De Block, C. E. M. & 7 others, Vonghia, L., Francque, S., Beuers, U., Gerdes, V. E. A., Bäckhed, F., Groen, A. K. & Nieuwdorp, M., 2022, In: Nature Medicine. 28, p. 2100-2106

Research output: Contribution to journal › Journal article › Research › peer-review

A systems biology approach to study non-alcoholic fatty liver (NAFL) in women with obesity

Meijnikman, A. S., Lappa, D., Herrema, H., Aydin, O., Krautkramer, K. A., Tremaroli, V., Olofsson, L. E., Lundqvist, A., Bruin, S., Acherman, Y., Verheij, J., Hjorth, Siv Annegrethe, Gerdes, V. E. A., Schwartz, Thue W., Groen, A. K., Bäckhed, F., Nielsen, J. & Nieuwdorp, M., 2022, In: iScience. 25, 8, 18 p., 104828.

Research output: Contribution to journal › Journal article › Research › peer-review

Distinct differences in gut microbial composition and functional potential from lean to morbidly obese subjects

Meijnikman, A. S., Aydin, O., Prodan, A., Tremaroli, V., Herrema, H., Levin, E., Acherman, Y., Bruin, S., Gerdes, V. E., Backhed, F., Groen, A. K. & Nieuwdorp, M., 2020, In: Journal of Internal Medicine. 288, 6, p. 699-710

Research output: Contribution to journal › Journal article › Research › peer-review

Acute effects of linagliptin on intact and total glucagon-like peptide-1 and gastric inhibitory polypeptide levels in insulin-dependent type 2 diabetes patients with and without moderate renal impairment

Meier, J. J., Quast, D. R., Nauck, M. A., Schenker, N., Deacon, Carolyn F., Holst, Jens Juul, Plum-Mörschel, L. & Kapitza, C., 2022, In: Diabetes, Obesity and Metabolism. 24, 5, p. 806-815

Research output: Contribution to journal › Journal article › Research › peer-review

Variation in genes related to hepatic lipid metabolism and changes in waist circumference and body weight

Meidtner, K., Fisher, E., Ängquist, Lars, Holst, C., Vimaleswaran, K. S., Boer, J. M. A., Halkjær, J., Masala, G., Ostergaard, J. N., Mortensen, L. M., van der A, D. L., Tjønneland, A., Palli, D., Overvad, K., Wareham, N. J., Loos, R. J. F., Sørensen, Thorkild I.A. & Boeing, H., Mar 2014, In: Genes & Nutrition. 9, p. 1-11 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Parenteral nutrition impairs plasma bile acid and gut hormone responses to mixed meal testing in lean healthy men

Meessen, E. C. E., Bakker, G. J., Nieuwdorp, M., Dallinga-Thie, G. M., Kemper, E. M., Olde Damink, S. W., Romijn, J. A., Hartmann, Bolette, Holst, Jens Juul, Knop, Filip Krag, Groen, A. K., Schaap, F. G. & Soeters, M. R., 2021, In: Clinical Nutrition. 40, 3, p. 1013-1021

Research output: Contribution to journal › Journal article › Research › peer-review

Effects of levothyroxine substitution therapy on hunger and food intake in individuals with hypothyroidism

Medici, B. R., Nygaard, Birte, la Cour, J. L., Krakauer, M., Brønden, Andreas, Sonne, M. P., Holst, Jens Juul, Rehfeld, Jens Frederik, Vilsbøll, Tina, Faber, J. & Knop, Filip Krag, 2023, In: Endocrine Connections. 12, 10, 14 p., e230314.

Research output: Contribution to journal › Journal article › Research › peer-review

Predictors of Improvement in Quality of Life When Treating Hypothyroidism

Medici, B. B., Lerche la Cour, J., Knop, Filip Krag, Krakauer, M., Michaelsson, L. F., Faber, Jens, Watt, Torquil & Nygaard, Birte, 2021, In: Journal of Thyroid Research. 2021, 7 p., 5577217.

Research output: Contribution to journal › Journal article › Research › peer-review

Methodology for Accurate Detection of Mitochondrial DNA Methylation

Mechta, Mie, Ingerslev, L. R. & Barrès, Romain, 2018, In: Journal of Visualized Experiments. 135, e57772.

Research output: Contribution to journal › Journal article › Research › peer-review

Evidence Suggesting Absence of Mitochondrial DNA Methylation

Mechta, Mie, Ingerslev, L. R., Fabre, O., Picard, M. & Barrès, Romain, 1 Nov 2017, In: Frontiers in Genetics. 8, 9 p., 166.

Research output: Contribution to journal › Journal article › Research › peer-review

Genetic correlation between amyotrophic lateral sclerosis and schizophrenia

McLaughlin, R. L., Schijven, D., Van Rheenen, W., Van Eijk, K. R., O'Brien, M., Kahn, R. S., Ophoff, R. A., Goris, A., Bradley, D. G., Al-Chalabi, A., Van Den Berg, L. H., Luykx, J. J., Hardiman, O., Veldink, J. H., Shatunov, A., Dekker, A. M., Diekstra, F. P., Pulit, S. L., Van Der Spek, R. A. A., Van Doormaal, P. T. C. & 31 others, Sproviero, W., Jones, A. R., Nicholson, G. A., Rowe, D. B., Pamphlett, R., Kiernan, M. C., Bauer, D., Kahlke, T., Williams, K., Eftimov, F., Fogh, I., Ticozzi, N., Lin, K., Millecamps, S., Salachas, F., Meininger, V., Carvalho, M. D., Pinto, S., Mora, J. S., Rojas-Garcyá, R., Polak, M., Chandran, S., Andersen, P. M., Pers, Tune H, Hansen, M., Hansen, T., Li, T., Olsen, L., Rasmussen, H. B., Werge, Thomas & Project MinE GWAS Consortium & Schizophrenia Working Group of the Psychiatric Genomics Consortium, P. M. G. C. &. S. W. G. O. T. P. G. C., 2017, In: Nature Communications. 8, 14774.

Research output: Contribution to journal › Journal article › Research › peer-review

Transforming growth factor β1 impairs the transcriptomic response to contraction in myotubes from women with polycystic ovary syndrome

McIlvenna, L. C., Altıntaş, Ali, Patten, R. K., McAinch, A. J., Rodgers, R. J., Stepto, N. K., Barrès, Romain & Moreno-Asso, A., 2022, In: The Journal of Physiology. 600, 14, p. 3313-3330

Research output: Contribution to journal › Journal article › Research › peer-review

Childhood height and risk of testicular germ cell tumors in adulthood

McGlynn, K. A., Petrick, J. L., Gamborg, Michael Orland, Aarestrup, J. & Baker, J. L., 2019, In: International Journal of Cancer. 143, 4, p. 767-772 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review