- Published
Critical role for GLP-1 in symptomatic post-bariatric hypoglycaemia
Craig, C. M., Liu, L., Deacon, Carolyn F., Holst, Jens Juul & McLaughlin, T. L., Mar 2017, In: Diabetologia. 60, 3, p. 531-540Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Use of Gastrostomy Tube for the Long-Term Remission of Hyperinsulinemic Hypoglycemia After Roux-en-y Gastric Bypass: A Case Report
Craig, C., Lamendola, C., Holst, Jens Juul, Deacon, Carolyn F. & McLaughlin, T., 2015, In: AACE Clinical Case Reports. 1, 2, p. e84-e87 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Salivary ghrelin response to drinks varying in protein content and quantity and association with energy intake and appetite.
Crabtree, D. R., Buosi, W., Fyfe, C. L., Horgan, G. W., Holst, Jens Juul, Johnstone, A. M. & Full4Health-study Group, F. G., 2021, In: Physiology and Behavior. 242, 113622.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Appetite Control across the Lifecourse: The Acute Impact of Breakfast Drink Quantity and Protein Content. The Full4Health Project
Crabtree, D. R., Buosi, W., Fyfe, C. L., Horgan, G. W., Manios, Y., Androutsos, O., Giannopoulou, A., Finlayson, G., Beaulieu, K., Meek, C. L., Holst, Jens Juul, Van Norren, K., Mercer, J. G., Johnstone, A. M. & FullHealth Study Grp, F. S. G., 2020, In: Nutrients. 12, 12, 26 p., 3710.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modulation of gut microbiota by Mantequilla and Melipona honeys decrease low-grade inflammation caused by high fructose corn syrup or sucrose in rats
Coutiño-Hernández, D., Sánchez-Tapia, M., Leal-Vega, F., Bobadilla del Valle, M., Ledezma, H., Cervantes, R., Pedraza-Chaverri, J., Granados-Portillo, O., Díaz, D., Antunes-Ricardo, M., Gutiérrez-Uribe, J., Maya, Otoniel, Olin-Sandoval, V., Tovar, A. R. & Torres, N., 2022, In: Food Research International. 151, 13 p., 110856.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of weight loss achieved through a multidisciplinary intervention on appetite in patients with severe obesity
Coutinho, S. R., Rehfeld, Jens Frederik, Holst, Jens Juul, Kulseng, B. & Martins, C., Jul 2018, In: American Journal of Physiology: Endocrinology and Metabolism. 315, 1, p. E91-E98Research output: Contribution to journal › Journal article › Research › peer-review
- Published
First Genome-Wide Association Study of Latent Autoimmune Diabetes in Adults Reveals Novel Insights Linking Immune and Metabolic Diabetes
Cousminer, D. L., Ahlqvist, E., Mishra, R., Andersen, M. K., Chesi, A., Hawa, M. I., Davis, A., Hodge, K. M., Bradfield, J. P., Zhou, K., Guy, V. C., Akerlund, M., Wod, M., Fritsche, L. G., Vestergaard, H., Snyder, J., Højlund, K., Linneberg, A., Karajamaki, A., Brandslund, I. & 33 others, , 2018, In: Diabetes Care. 41, 11, p. 2396-2403Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty
The ReproGen Consortium, T. R. C., The Early Growth Genetics (EGG) Consortium, T. E. G. G. (. C., The Early Growth Genetics (EGG) Consortium, T. E. G. G. (. C., The ReproGen Consortium, T. R. C. & The GIANT Consortium, T. G. C., 1 Jan 2014, In: Human Molecular Genetics. 23, 16, p. 4452-4464 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide Association and Longitudinal Analyses Reveal Genetic Loci Linking Pubertal Height Growth, Pubertal Timing, and Childhood Adiposity
Cousminer, D. L., Berry, D. J., Timpson, N. J., Ang, X. W. E., Thiering, E., Byrne, E., Taal, H. R., Huikari, V., Bradfield, J. P., Kerkhof, M., Groen-Blokhuis, M. M., Kreiner-Møller, E., Marinelli, M., Holst, C., Leinonen, J. T., Perry, J. R. B., Surakka, I., Pietiläinen, O., Kettunen, J., Anttila, V. & 31 others, , 2013, In: Human Molecular Genetics. 22, 13Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer
Couch, F. J., Kuchenbaecker, K. B., Michailidou, K., Mendoza-Fandino, G. A., Nord, S., Lilyquist, J., Olswold, C., Hallberg, E., Agata, S., Ahsan, H., Aittomäki, K., Ambrosone, C. B., Andrulis, I. L., Anton-Culver, H., Arndt, V., Arun, B. K., Arver, B., Barile, M., Barkardottir, R. B., Barrowdale, D. & 229 others, , 2016, In: Nature Communications. 7, p. 1-13 13 p., 11375.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Enterotypes in the landscape of gut microbial community composition
Costea, P. I., Hildebrand, F., Manimozhiyan, A., Bäckhed, F., Blaser, M. J., Bushman, F. D., De Vos, W. M., Ehrlich, S. D., Fraser, C. M., Hattori, M., Huttenhower, C., Jeffery, I. B., Knights, D., Lewis, J. D., Ley, R. E., Ochman, H., O'Toole, P. W., Quince, C., Relman, D. A., Shanahan, F. & 9 others, , 2018, In: Nature Microbiology. 3, 1, p. 8-16 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ellagic acid prevents myocardial infarction-induced left ventricular diastolic dysfunction in ovariectomized rats
Costa, B. M., Mengal, V., Brasil, G. A., Peluso, A. A., Treebak, Jonas Thue, Endlich, P. W., de Almeida, S. A. & de Abreu, G. R., 2022, In: Journal of Nutritional Biochemistry. 105, 9 p., 108990.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neuronal apoptosis in the neonates born to preeclamptic mothers
Cosar, H., Ozer, E., Topel, Hande, Kahramaner, Z., Turkoglu, E., Erdemir, A., Sutcuoglu, S., Bagriyanik, A. & Ozer, E. A., Jul 2013, In: Journal of Maternal-Fetal Medicine. 26, 11, p. 1143-6 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acute Deletion of the Glucocorticoid Receptor in Hepatocytes Disrupts Postprandial Lipid Metabolism in Male Mice
Correia, C. M., Præstholm, S. M., Havelund, J. F., Pedersen, F. B., Siersbæk, M. S., Ebbesen, M. F., Gerhart-Hines, Zach, Heeren, J., Brewer, J., Larsen, Steen, Blagoev, B., Færgeman, N. J. & Grøntved, L., 2023, In: Endocrinology. 164, 10, p. 1-17 164.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Obesity-related polymorphisms and their associations with the ability to regulate fat oxidation in obese europeans: The NUGENOB Study
Corpeleijn, E., Petersen, L., Holst, C., Saris, W. H., Astrup, A., Langin, D., Macdonald, I., Martinez, J. A., Oppert, J., Polak, J., Pedersen, Oluf Borbye, Froguel, P., Arner, P., Sørensen, Thorkild I.A. & Blaak, E. E., 2010, In: Obesity. 18, 7, p. 1369-1377 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Getting from A to B-exploring the activation motifs of the class B adhesion G protein-coupled receptor subfamily G member 4/GPR112
Cornelia Peeters, M., Mos, I., Lenselink, E. B., Lucchesi, M., IJzerman, A. P. & Schwartz, Thue W., May 2016, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 30, 5, p. 1836-1848 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The adhesion G protein-coupled receptor G2 (ADGRG2/GPR64) constitutively activates SRE and NFκB and is involved in cell adhesion and migration
Cornelia Peeters, M., Fokkelman, M., Boogaard, B., Egerod, Kristoffer Lihme, van de Water, B., IJzerman, A. P. & Schwartz, Thue W., Dec 2015, In: Cellular Signalling. 27, 12, p. 2579-88 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Childhood Height and Birth Weight in Relation to Future Prostate Cancer Risk: A Cohort Study Based on the Copenhagen School Health Records Register
Cook, M. B., Gamborg, M., Aarestrup, J., Sørensen, Thorkild I.A. & Baker, J. L., Dec 2013, In: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 22, 12, p. 2232-2240 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Childhood body mass index in relation to future risk of oesophageal adenocarcinoma
Cook, M. B., Freedman, N. D., Gamborg, Michael Orland, Sørensen, Thorkild I.A. & Baker, J. L., 2015, In: B J C. 112, p. 601-607 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impairments in site-specific AS160 phosphorylation and effects of exercise training
Consitt, L. A., Van Meter, J., Newton, C. A., Collier, D. N., Dar, M. S., Wojtaszewski, Jørgen F P, Treebak, Jonas Thue, Tanner, C. J. & Houmard, J. A., 2013, In: Diabetes. 62, 10, p. 3437-3447 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Seven mutations in the human insulin gene linked to permanent neonatal/infancy-onset diabetes mellitus
Colombo, C., Porzio, O., Liu, M., Massa, O., Vasta, M., Salardi, S., Beccaria, L., Monciotti, C., Toni, S., Pedersen, Oluf Borbye, Hansen, T., Federici, L., Pesavento, R., Cadario, F., Federici, G., Ghirri, P., Arvan, P., Iafusco, D., Barbetti, F. & Early Onset Diabetes Study Group of the Italian Society of Pediatric Endocrinology and Diabetes (SIEDP), E. O. D. S. G. O. T. I. S. O. P. E. A. D. (., 2008, In: Journal of Clinical Investigation. 118, 6, p. 2148-56 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls
Coleman, J. R. I., Gaspar, H. A., Bryois, J., Byrne, E. M., Forstner, A. J., Holmans, P. A., de Leeuw, C. A., Mattheisen, M., McQuillin, A., Whitehead Pavlides, J. M., Pers, T. H., Ripke, S., Stahl, E. A., Steinberg, S., Trubetskoy, V., Trzaskowski, M., Wang, Y., Abbott, L., Abdellaoui, A., Adams, M. J. & 32 others, , 2020, In: Biological Psychiatry. 88, 2, p. 169-184 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Many obese individuals experience wheezing, rather than asthma: A Mendelian randomization study of 86,019 adults
Colak, Y., Afzal, Shoaib, Lange, Peter & Nordestgaard, Børge, 2015, In: European Respiratory Journal.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
High BMI And Risk Of Exacerbations And Pneumonias In Individuals With COPD: Observational And Genetic Risk Estimates From The Copenhagen General Population Study
Colak, Y., Afzal, Shoaib, Lange, Peter & Nordestgaard, Børge, 2016, In: American Journal of Respiratory and Critical Care Medicine. 193, 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Gut microbiota composition in patients with newly diagnosed bipolar disorder and their unaffected first-degree relatives
Coello, K., Hansen, T. H., Sørensen, N., Munkholm, K., Kessing, Lars Vedel, Pedersen, Oluf Borbye & Vinberg, Maj, 2019, In: Brain, Behavior, and Immunity. 75, p. 112-118Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Affective disorders impact prevalence of Flavonifractor and abundance of Christensenellaceae in gut microbiota
Coello, K., Hansen, T. H., Sørensen, N., Ottesen, N. M., Miskowiak, Kamilla, Pedersen, Oluf Borbye, Kessing, Lars Vedel & Vinberg, Maj, 2021, In: Progress in Neuro-Psychopharmacology and Biological Psychiatry. 110, 110300.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multiomics signatures of type 1 diabetes with and without albuminuria
Clos-Garcia, M., Ahluwalia, Tarun Veer Singh, Winther, S. A., Henriksen, P., Ali, M., Fan, Yong, Stankevic, Evelina, Lyu, Liwei, Vogt, J. K., Hansen, Torben, Legido-Quigley, C., Rossing, Peter & Pedersen, Oluf Borbye, 2022, In: Frontiers in Endocrinology. 13, 17 p., 1015557.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of fasting duration and weekday in incretin and glucose regulation
Clemmensen, K. K. B., Quist, J. S., Vistisen, D., Witte, D. R., Jonsson, Anna Elisabet, Pedersen, Oluf Borbye, Hansen, Torben, Holst, Jens Juul, Lauritzen, T., Jørgensen, M. E., Torekov, Signe Sørensen & Færch, K., 2020, In: Endocrine Connections. 9, 4, p. 279-288Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No effects of dapagliflozin, metformin or exercise on plasma glucagon concentrations in individuals with prediabetes: A post hoc analysis from the randomized controlled PRE-D trial
Clemmensen, K. K. B., Blond, M. B., Amadid, H., Bruhn, L., Vistisen, D., Karstoft, K., Persson, F., Ried-Larsen, M., Holst, Jens Juul, Albrechtsen, Nicolai Jacob Wewer, Torekov, Signe Sørensen, Quist, J. S., Jorgensen, M. E. & Faerch, K., 2021, In: Diabetes, Obesity and Metabolism. 23, 2, p. 530-539Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Robust GLP-1 secretion by basic L-amino acids does not require the GPRC6A receptor
Clemmensen, Christoffer, Jørgensen, C. V., Smajilovic, S. & Bräuner, Hans, 2017, In: Diabetes, Obesity and Metabolism. 19, 4, p. 599-603Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased susceptibility to diet-induced obesity in GPRC6A receptor knockout mice
Clemmensen, Christoffer, Smajilovic, S., Madsen, A. N., Klein, A. B., Holst, Birgitte & Bräuner, Hans, 2013, In: Journal of Endocrinology. 217, 2, p. 151-60 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Enhanced voluntary wheel running in GPRC6A receptor knockout mice
Clemmensen, Christoffer, Pehmøller, C., Klein, A. B., Ratner, C., Wojtaszewski, Jørgen F P & Bräuner, Hans, 2013, In: Physiology & Behavior. 118, p. 144-151 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes
Clemmensen, C., Jall, S., Kleinert, M., Quarta, C., Gruber, T., Reber, J., Sachs, S., Fischer, K., Feuchtinger, A., Karlas, A., Simonds, S. E., Grandl, G., Loher, D., Sanchez-Quant, E., Keipert, S., Jastroch, M., Hofmann, S. M., Nascimento, E. B. M., Schrauwen, P., Ntziachristos, V. & 4 others, , 2018, In: Nature Communications. 9, 13 p., 4304.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1/glucagon coagonism restores leptin responsiveness in obese mice chronically maintained on an obesogenic diet
Clemmensen, Christoffer, Chabenne, J., Finan, B., Sullivan, L., Fischer, K., Küchler, D., Sehrer, L., Ograjsek, T., Hofmann, S. M., Schriever, S. C., Pfluger, P. T., Pinkstaff, J., Tschöp, M. H., Dimarchi, R. & Müller, T. D., Apr 2014, In: Diabetes. 63, 4, p. 1422-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Will the COVID-19 pandemic worsen the obesity epidemic?
Clemmensen, Christoffer, Petersen, M. B. & Sørensen, Thorkild I.A., 2020, In: Nature Reviews Endocrinology. 2 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Emerging hormonal-based combination pharmacotherapies for the treatment of metabolic diseases
Clemmensen, Christoffer, Finan, B., Müller, T. D., DiMarchi, R. D., Tschöp, M. H. & Hofmann, S. M., 2019, In: Nature Reviews Endocrinology. 15, p. 90-104Research output: Contribution to journal › Review › Research › peer-review
- Published
Dual melanocortin-4 receptor and GLP-1 receptor agonism amplifies metabolic benefits in diet-induced obese mice
Clemmensen, Christoffer, Finan, B., Fischer, K., Tom, R. Z., Legutko, B., Sehrer, L., Heine, D., Grassl, N., Meyer, C. W., Henderson, B., Hofmann, S. M., Tschöp, M. H., Van der Ploeg, L. H. T. & Müller, T. D., Mar 2015, In: EMBO Molecular Medicine. 7, 3, p. 288-98 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cognitive function in adult offspring of women with gestational diabetes-the role of glucose and other factors
Clausen, T. D., Mortensen, Erik Lykke, Schmidt, Lone, Mathiesen, Elisabeth, Hansen, Torben, Jensen, D. M. & Damm, Peter, 2013, In: PLOS ONE. 8, 6, e67107.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High prevalence of type 2 diabetes and pre-diabetes in adult offspring of women with gestational diabetes mellitus or type 1 diabetes: the role of intrauterine hyperglycemia
Clausen, Tine Dalsgaard, Mathiesen, E. R., Hansen, T., Pedersen, Oluf Borbye, Jensen, D. M., Lauenborg, J., Damm, Peter, Clausen, T. D., Mathiesen, Elisabeth, Hansen, T., Pedersen, O., Jensen, D., Lauenborg, J. & Damm, Peter, 1 Feb 2008, In: Diabetes Care. 31, 2, p. 340-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Overweight and the metabolic syndrome in adult offspring of women with diet-treated gestational diabetes mellitus or type 1 diabetes
Clausen, Tine Dalsgaard, Mathiesen, E. R., Hansen, T., Pedersen, Oluf Borbye, Jensen, D. M., Lauenborg, J., Schmidt, Lone, Damm, Peter, Clausen, T. D., Mathiesen, Elisabeth, Hansen, T., Pedersen, O., Jensen, D., Lauenborg, J., Schmidt, L. & Damm, Peter, 1 Jul 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 7, p. 2464-70 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of Acute GLP-1 Infusion on Pulmonary and Systemic Hemodynamics in Patients With Heart Failure: A Pilot Study
Clarke, S. J., Pettit, S., Giblett, J. P., Zhao, T., Kydd, A. C., Albrechtsen, Nicolai Jacob Wewer, Deacon, Carolyn F., Parameshwar, J. & Hoole, S. P., 2019, In: Clinical Therapeutics. 41, 1, p. 118-127 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1 Is a Coronary Artery Vasodilator in Humans
Clarke, S. J., Giblett, J. P., Yang, L. L., Hubsch, A., Zhao, T., Aetesam-ur-Rahman, M., West, N. E. J., O'Sullivan, M., Figg, N., Bennett, M., Albrechtsen, Nicolai Jacob Wewer, Deacon, Carolyn F., Cheriyan, J. & Hoole, S. P., 20 Nov 2018, In: Journal of the American Heart Association. 7, 22, 14 p., e010321.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Overexpression of protein kinase STK25 in mice exacerbates ectopic lipid accumulation, mitochondrial dysfunction and insulin resistance in skeletal muscle
Chursa, U., Nuñez-Durán, E., Cansby, E., Amrutkar, M., Sütt, S., Ståhlman, M., Olsson, B., Borén, J., Johansson, M. E., Bäckhed, G. F., Johansson, B. R., Sihlbom, C. & Mahlapuu, M., Mar 2017, In: Diabetologia. 60, 3, p. 553-567 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regular exercise effectively protects against the aging-associated decline in skeletal muscle NAD content
Chubanava, Sabina & Treebak, Jonas Thue, 2023, In: Experimental Gerontology. 173, 112109.Research output: Contribution to journal › Review › Research › peer-review
- Published
Effect of endogenous hypergastrinemia on gastrin receptor expressing human colon carcinoma transplanted to athymic rats.
Chu, M., Franzén, L., Rehfeld, J. F., Holst, Jens Juul & Borch, K., 1995, In: Today in Medicine. Gastroenterology. 109, p. 1415-1420Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Apolipoprotein M/S1P Axis Controls Triglyceride Metabolism and Brown Fat Activity
Christoffersen, Christina, Federspiel, C. K., Borup, A., Christensen, P. M., Madsen, A. N., Heine, M., Nielsen, C. H., Kjaer, A., Holst, Birgitte, Heeren, J. & Nielsen, L. B., 2 Jan 2018, In: Cell Reports. 22, 1, p. 175-188Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulinoma in a third-trimester pregnant woman combined with pre-eclampsia: a case report and review of the diagnostic strategies
Christiansen, P. E. & drb459, drb459, Jul 2008, In: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology. 24, 7, p. 417-22 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A novel dopamine transporter transgenic mouse line for identification and purification of midbrain dopaminergic neurons reveals midbrain heterogeneity
Apuschkin, Mia, Stilling, S., Rahbek-Clemmensen, T., Sørensen, G., Fortin, G., Herborg, Freja, Eriksen, J., Trudeau, L., Egerod, Kristoffer Lihme, Gether, Ulrik & Rickhag, Karl Mattias, 2015, In: European Journal of Neuroscience. 42, 7, p. 2438-2454 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mendelian randomization suggests a causal effect of abdominal obesity on postprandial lipemia
Christiansen, Malene Revsbech, Hansen, Torben, Sørensen, Thorkild I.A., Grarup, N., García Ureña, Mario, Borisevich, D., Oppert, J., Martinez Hernandez, J. A., Blaak, E. & Kilpeläinen, Tuomas O., 2022, In: European Journal of Human Genetics. 30, Supplement 1, p. 184 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Abdominal Obesity Genetic Variants Predict Waist Circumference Regain After Weight Loss
Christiansen, Malene Revsbech, Kilpeläinen, Tuomas O. & McCaffery, J. M., 2023, In: Diabetes. 72, 10, p. 1424-1432 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Abdominal and gluteofemoral fat depots show opposing associations with postprandial lipemia
Christiansen, Malene Revsbech, García Ureña, Mario, Borisevich, D., Grarup, N., Martínez, J. A., Oppert, J., Sørensen, Thorkild I.A., Hansen, Torben, Blaak, E. E. & Kilpeläinen, Tuomas O., 2021, In: American Journal of Clinical Nutrition. 114, 4, p. 1467–1475 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of abdominal obesity on postprandial lipid concentrations
Christiansen, Malene Revsbech, Sørensen, Thorkild I.A., Hansen, Torben & Kilpeläinen, Tuomas O., 2020, In: European Journal of Human Genetics. 28, Suppl. 1, p. 279-280 2 p.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Influence of peptides on anorectal function
Christiansen, J., Lorentzen, M. & Holst, Jens Juul, 1991, In: Annals of Medicine. 22, p. 413-418Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impaired insulin-stimulated nonoxidative glucose metabolism in pancreas-kidney transplant recipients: dose-response effects of insulin on glucose turnover
Christiansen, E., drb459, drb459, Tibell, A., Hother-Nielsen, O., Holst, Jens Juul, Pedersen, O. & Madsbad, Sten, 1996, In: Diabetes. 45, 9, p. 1267-75 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The VGF-Derived Neuropeptide TLQP-21 Shows No Impact on Hormone Secretion in the Isolated Perfused Rat Pancreas
Christiansen, Charlotte Bayer, Svendsen, B. & Holst, Jens Juul, 20 Jan 2015, In: Hormone and Metabolic Research. 47, 07, p. 537-43 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The impact of short chain fatty acids on GLP-1 and PYY secretion from the isolated perfused rat colon
Christiansen, Charlotte Bayer, Gabe, M. B. N., Svendsen, B., Dragsted, Lars Ove, Rosenkilde, Mette & Holst, Jens Juul, 2018, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 315, 1, p. G53-G65 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Colonic lactulose fermentation has no impact on glucagon-like peptide-1 and peptide-YY secretion in healthy young men
Christiansen, Charlotte Bayer, Veedfald, Simon, Hartmann, Bolette, Gauguin, A. M., Møller, Søren, Moritz, Thomas, Madsbad, Sten & Holst, Jens Juul, 2022, In: Journal of Clinical Endocrinology and Metabolism. 107, 1, p. 77-87Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bile acids drive colonic secretion of glucagon-like-peptide 1 and peptide-YY in rodents
Christiansen, Charlotte Bayer, Trammell, Sam, Albrechtsen, Nicolai Jacob Wewer, Schoonjans, K., Albrechtsen, Reidar, Gillum, M. P., Kuhre, Rune Ehrenreich & Holst, Jens Juul, 2019, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 316, 5, p. G574-G584 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acute administration of interleukin-6 does not increase secretion of glucagon-like peptide-1 in mice
Christiansen, Charlotte Bayer, Jepsen, Sara Lind, Svendsen, B., Balk-Møller, E., Dahlby, T., Kuhre, Rune Ehrenreich, Hartmann, Bolette, Mandrup-Poulsen, Thomas, Deacon, Carolyn F., Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2018, In: Physiological Reports. 6, 13, p. 1-8 e13788.Research output: Contribution to journal › Journal article › Research › peer-review
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Volume of ropivacaine 0.2% and common peroneal nerve block duration: a randomised, double-blind cohort trial in healthy volunteers
Christiansen, Charlotte Bayer, Madsen, M. H., Rothe, C., Andreasen, A. M., Lundstrøm, L. H. & Lange, Kai, 2018, In: Anaesthesia. 73, 11, p. 1361-1367 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Benefit-Risk Assessment of Obesity Drugs: Focus on Glucagon-like Peptide-1 Receptor Agonists
Christensen, R. M., Juhl, C. R. & Torekov, Signe Sørensen, 2019, In: Drug Safety. 42, 8, p. 957-971 15 p.Research output: Contribution to journal › Review › Research › peer-review
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Glucose-Dependent Insulinotropic Polypeptide (GIP) Reduces Bone Resorption in Patients With Type 2 Diabetes
Christensen, Mikkel Bring, Lund, A. B., Jørgensen, Niklas Rye, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2020, In: Journal of the endocrine society. 4, 9, 9 p., 097.Research output: Contribution to journal › Journal article › Research › peer-review
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GIP's involvement in the pathophysiology of type 2 diabetes
Christensen, Mikkel Bring, Gasbjerg, Lærke Smidt, Heimbürger, S. M., Stensen, S., Vilsbøll, Tina & Knop, Filip Krag, Mar 2020, In: Peptides. 125, 10 p., 170178.Research output: Contribution to journal › Review › Research › peer-review
- Published
Glucose-Dependent Insulinotropic Polypeptide (GIP) Inhibits Bone Resorption Independently of Insulin and Glycemia
Christensen, Mikkel Bring, Lund, A., Calanna, S., Jørgensen, Niklas Rye, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 1 Jan 2018, In: The Journal of clinical endocrinology and metabolism. 103, 1, p. 288-294Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucose-dependent Insulinotropic Polypeptide: Blood Glucose Stabilizing Effects in Patients With Type 2 Diabetes
Christensen, Mikkel Bring, Calanna, S., Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, Mar 2014, In: The Journal of clinical endocrinology and metabolism. 99, 3, p. E418-26 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucose-dependent insulinotropic polypeptide: a bifunctional glucose-dependent regulator of glucagon and insulin secretion in humans
Christensen, M., Vedtofte, L., Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2011, In: Diabetes. 60, 12, p. 3103-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucose-Dependent Insulinotropic Polypeptide Augments Glucagon Responses to Hypoglycemia in Type 1 Diabetes
Christensen, Mikkel Bring, Calanna, S., wbf943, wbf943, Kristensen, P. L., Rosenkilde, Mette, Faber, Jens, Purrello, F., van Hall, Gerrit, Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, Jan 2015, In: Diabetes. 64, 1, p. 72-78 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lixisenatide for type 2 diabetes mellitus
Christensen, M., Knop, Filip Krag, Vilsbøll, Tina & Holst, Jens Juul, 2011, In: Expert Opinion on Investigational Drugs. 20, 4, p. 549-57 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Establishing post mortem criteria for the metabolic syndrome: an autopsy based cross-sectional study
Christensen, M. R., Bugge, A., Malik, M. E., Thomsen, J. L., Lynnerup, Niels, Rungby, Jørgen & Banner, Jytte, 2018, In: Diabetology & Metabolic Syndrome. 10, 1, 8 p., 36.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transfer of liraglutide from blood to cerebrospinal fluid is minimal in patients with type 2 diabetes
Christensen, M., wbf943, wbf943, Hartmann, Bolette, Grevstad, U., Rosenkilde, Mette, Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, Nov 2015, In: International journal of obesity (2005). 39, 11, p. 1651-1654 4 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Vascular, but not luminal, activation of FFAR1 (GPR40) stimulates GLP-1 secretion from isolated perfused rat small intestine
Christensen, L. W., Kuhre, Rune Ehrenreich, Janus, C., Svendsen, B. & Holst, Jens Juul, 17 Sep 2015, In: Physiological Reports. 3, 9, p. 1-13 13 p., e122551.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functional Screening Identifies miRNAs Influencing Apoptosis and Proliferation in Colorectal Cancer
Christensen, L. L., Holm, A., Rantala, J., Kallioniemi, O., Rasmussen, M. H., Ostenfeld, M. S., Dagnaes-Hansen, F., Oster, B., Schepeler, T., Tobiasen, H., Thorsen, K., Sieber, O. M., Gibbs, P., Lamy, P., Hansen, T. F., Jakobsen, A., Riising, E. M., Helin, K., Lubinski, J., Hagemann-Madsen, R. & 3 others, , 2014, In: PLOS ONE. 9, 6, p. e96767Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pregnancy and childhood exposure to residential traffic noise and overweight at 7 years of age
Christensen, J. S., Hjortebjerg, D., Raaschou-Nielsen, O., Ketzel, M., Sørensen, Thorkild I.A. & Sørensen, M., Sep 2016, In: Environment International. 94, 9, p. 170-176 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Road Traffic and Railway Noise Exposures and Adiposity in Adults: A Cross-Sectional Analysis of the Danish Diet, Cancer, and Health Cohort
Christensen, J. S., Raaschou-Nielsen, O., Tjønneland, A., Overvad, K., Nordsborg, R. B., Ketzel, M., Sørensen, Thorkild I.A. & Sørensen, M., Mar 2016, In: Environmental Health Perspectives. 124, 3, p. 329-35 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Long-term exposure to residential traffic noise and changes in body weight and waist circumference: A cohort study
Christensen, J. S., Raaschou-Nielsen, O., Tjønneland, A., Nordsborg, R. B., Jensen, S. S., Sørensen, Thorkild I.A. & Sørensen, M., Nov 2015, In: Environmental Research. 143, Pt A, p. 154-61 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cohort Profile: The Danish Conscription Database(DCD): A cohort of 728 160 men born from 1939 through 1959
Okholm, Gunhild Tidemann, Molbo, Drude, Ängquist, Lars, Mortensen, Erik Lykke, Christensen, K., Sørensen, Thorkild I.A. & Osler, Merete, 2015, In: International Journal of Epidemiology. 44, 2, p. 432-40Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The developing airway and gut microbiota in early life is influenced by age of older siblings
Christensen, E. D., Hjelmsø, M. H., Thorsen, Jonathan Jan Ilve, Shah, S., Redgwell, T., Poulsen, Christina Egeø, Trivedi, Urvish, Russel, J., Gupta, S., Chawes, Bo Lund Krogsgaard, Bønnelykke, Klaus, Sørensen, Søren Johannes, Rasmussen, Morten Arendt, Bisgaard, H. & Stokholm, Jakob, 2022, In: Microbiome. 10, 15 p., 106.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Environmental exposures are important for type 2 diabetes pathophysiology in sub-Saharan African populations
Christensen, Dirk Lund, Hjort, Line, Mpagama, S. G. & Ramaiya, K. L., 2023, In: Diabetologia. 66, p. 777–779 3 p.Research output: Contribution to journal › Letter › Research
- Published
Type 2 diabetes classification: a data-driven cluster study of the Danish Centre for Strategic Research in Type 2 Diabetes (DD2) cohort
Christensen, D. H., Nicolaisen, S. K., Ahlqvist, E., Stidsen, J. V., Nielsen, J. S., Hojlund, K., Olsen, M. H., García-Calzón, S., Ling, C., Rungby, Jørgen, Brandslund, I., Vestergaard, P., Jessen, N., Hansen, Torben, Brøns, C., Beck-Nielsen, H., Sørensen, H. T., Thomsen, R. W. & Vaag, Allan, 2022, In: B M J Open Diabetes Research & Care. 10, 2, 12 p., e002731.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lysine deacetylase inhibition prevents diabetes by chromatin-independent immunoregulation and β-cell protection
Christensen, D. P., Gysemans, C., Lundh, M., Dahllöf, M. S., Noesgaard, D., Schmidt, S. F., Mandrup, S., Birkbak, N., Workman, C., Piemonti, L., Blaabjerg, L., Monzani, V., Fossati, G., Mascagni, P., Paraskevas, S., Aikin, R. A., Billestrup, N., Grunnet, L. G., Dinarello, C. A., Mathieu, C. & 1 others, , 6 Jan 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 3, p. 1055-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Skeletal muscle to pancreatic β-cell cross-talk: the effect of humoral mediators liberated by muscle contraction and acute exercise on β-cell apoptosis
Christensen, C. S., P. Christensen, D., Lundh, M., Dahllöf, M. S., Haase, T. N., Velasquez, J. M., Laye, M. J., Mandrup-Poulsen, Thomas & Solomon, T. P. J., Oct 2015, In: Journal of Clinical Endocrinology and Metabolism. 100, 10, p. E1289-E1298 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Whey-reduced weight gain is associated with a temporary growth reduction in young mice fed a high-fat diet
Christensen, B. T., Madsen, A. N., Hansen, Axel Kornerup & Hellgren, L. I., Jan 2015, In: Journal of Nutritional Biochemistry. 26, 1, p. 9-15 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hvordan undgår man, at de tabte kilo kommer på igen?
Christensen, Bodil Just, Iepsen, E. P. W. & Torekov, Signe Sørensen, 29 May 2018, Forskerzonen.Research output: Other contribution › Net publication - Internet publication › Communication
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Patient profiling for success after weight loss surgery (GO Bypass study): An interdisciplinary study protocol
Christensen, Bodil Just, Schmidt, J. B., Nielsen, M. S., Tækker, L., Holm, Lotte, Lunn, Susanne, Bredie, Wender, Ritz, C., Holst, Jens Juul, Hansen, Torben, Hilbert, A., le Roux, C. W., Hulme, O. J., Siebner, Hartwig Roman, Morville, T., Naver, L., Floyd, A. K. & Sjödin, Anders Mikael, 2018, In: Contemporary Clinical Trials Communications. 10, p. 121-130 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Instrumentalization of eating improves weight loss maintenance in obesity
Christensen, Bodil Just, Iepsen, E. P. W., Lundgren, J. R., Holm, Lotte, Madsbad, Sten, Holst, Jens Juul & Torekov, Signe Sørensen, 2017, In: Obesity Facts. 10, 6, p. 633-647 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glimepiride monotherapy versus combination of glimepiride and linagliptin therapy in patients with HNF1A-diabetes: a protocol for a randomised, double-blinded, placebo-controlled trial
Christensen, A. S., Storgaard, H., Hædersdal, S., Hansen, Torben, Knop, Filip Krag & Vilsbøll, Tina, 2018, In: BMJ Open. 8, p. 1-9 e022517.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Efficacy and Safety of Glimepiride With or Without Linagliptin Treatment in Patients With HNF1A Diabetes (Maturity-Onset Diabetes of the Young Type 3): A Randomized, Double-Blinded, Placebo-Controlled, Crossover Trial (GLIMLINA)
Christensen, A. S., Haedersdal, S., Stoy, J., Storgaard, H., Kampmann, U., Forman, Julie Lyng, Seghieri, M., Holst, Jens Juul, Hansen, Torben, Knop, Filip Krag & Vilsbøll, Tina, 2020, In: Diabetes Care. 43, 9, p. 2025-2033 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GIP and GLP-1 Potentiate Sulfonylurea-Induced Insulin Secretion in HNF1A Diabetes
Christensen, A. S., Haedersdal, S., Storgaard, H., Rose, K., Hansen, N. L., Holst, Jens Juul, Hansen, Torben, Knop, Filip Krag & Vilsbøll, Tina, 2019, In: Diabetes. 68, Suppl. 1, 1 p., 981-P.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
GIP and GLP-1 Potentiate Sulfonylurea-Induced Insulin Secretion in Hepatocyte Nuclear Factor 1 alpha Mutation Carriers
Christensen, A. S., Haedersdal, S., Storgaard, H., Rose, K., Hansen, N. L., Holst, Jens Juul, Hansen, Torben, Knop, Filip Krag & Vilsbøll, Tina, 2020, In: Diabetes. 69, 9, p. 1989-2002 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reply to ‘Lactate as a major myokine and exerkine’
Chow, L. S., Gerszten, R. E., Taylor, J. M., Pedersen, B. K., van Praag, H., Trappe, S., Febbraio, M. A., Galis, Z. S., Gao, Y., Haus, J. M., Lanza, I. R., Lavie, C. J., Lee, C. H., Lucia, A., Moro, C., Pandey, A., Robbins, J. M., Stanford, K. I., Thackray, A. E., Villeda, S. & 5 others, , 2022, In: Nature Reviews Endocrinology. 18, 11, p. 713 1 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Exerkines in health, resilience and disease
Chow, L. S., Gerszten, R. E., Taylor, J. M., Pedersen, B. K., van Praag, H., Trappe, S., Febbraio, M. A., Galis, Z. S., Gao, Y., Haus, J. M., Lanza, I. R., Lavie, C. J., Lee, C-H., Lucia, A., Moro, C., Pandey, A., Robbins, J. M., Stanford, K. I., Thackray, A. E., Villeda, S. & 5 others, , 2022, In: Nature Reviews Endocrinology. 18, p. 273-289Research output: Contribution to journal › Review › Research › peer-review
- Published
Feeding diversified protein sources exacerbates hepatic insulin resistance via increased gut microbial branched-chain fatty acids and mTORC1 signaling in obese mice
Choi, Beatrice So-Yun, Daniel, N., Houde, V. P., Ouellette, A., Marcotte, B., Varin, T. V., Vors, C., Feutry, P., Ilkayeva, O., Stahlman, M., St-Pierre, P., Bäckhed, F., Tremblay, A., White, P. J. & Marette, A., 2021, In: Nature Communications. 12, 16 p., 3377.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A functional IFN-λ4-generating DNA polymorphism could protect older asthmatic women from aeroallergen sensitization and associate with clinical features of asthma
Chinnaswamy, S., Wardzynska, A., Pawelczyk, M., Makowska, J., Skaaby, T., Mercader, J. M., Ahluwalia, T. S., Grarup, N., Guindo-Martinez, M., Bisgaard, H., Torrents, D., Linneberg, Allan René, Bønnelykke, Klaus & Kowalski, M. L., 5 Sep 2017, In: Scientific Reports. 7, 1, p. 1-11 11 p., 10500.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
EIF4A2 is a positional candidate gene at the 3q27 locus linked to type 2 diabetes in French families
Cheyssac, C., Dina, C., Leprêtre, F., Vasseur-Delannoy, V., Dechaume, A., Lobbens, S., Balkau, B., Ruiz, J., Charpentier, G., Pattou, F., Joly, E., Prentki, M., Hansen, Torben, Pedersen, Oluf Borbye, Vaxillaire, M. & Froguel, P., 2006, In: Diabetes. 55, 4, p. 1171-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucose-Dependent miR-125b Is a Negative Regulator of β-Cell Function
Cheung, R., Pizza, G., Chabosseau, P., Rolando, D., Tomas, A., Burgoyne, T., Wu, Z., Salowka, A., Thapa, A., Macklin, A., Cao, Y., Nguyen-Tu, M. S., Dickerson, M. T., Jacobson, D. A., Marchetti, P., Shapiro, J., Piemonti, L., de Koning, E., Leclerc, I., Bouzakri, K. & 4 others, , 2022, In: Diabetes. 71, 7, p. 1525-1545 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hindbrain circuits in the control of eating behaviour and energy balance
Cheng, W., Gordian, D., Ludwig, M. Q., Pers, Tune H, Seeley, R. J. & Myers, M. G., 2022, In: Nature Metabolism. 4, 7, p. 826-835 10 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Distinct life histories impact dikaryotic genome evolution in the rust fungus Puccinia striiformis causing stripe rust in wheat
Chen, Yan-Jun, Schwessinger, B., Tien, R., Vogt, J. K., Sperschneider, J., Nagar, R., McMullan, M., Sicheritz-Pontén, Thomas, Sørensen, C. K., Hovmøller, M. S., Rathjen, J. P. & Justesen, A. F., 2020, In: Genome Biology and Evolution. 12, 5, p. 597-617Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sequence of the human glycogen-associated regulatory subunit of type 1 protein phosphatase and analysis of its coding region and mRNA level in muscle from patients with NIDDM
Chen, Y. H., Hansen, L., Chen, M., Bjørbaek, C., drb459, drb459, Hansen, Teis Schjals, Cohen, P., Pedersen, Oluf Borbye & drb459, drb459, Oct 1994, In: Diabetes. 43, 10, p. 1234-41 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels
Chen, W-M., Erdos, M. R., Jackson, A. U., Saxena, R., Sanna, S., Silver, K. D., Timpson, N. J., Hansen, T., Orrù, M., Grazia Piras, M., Bonnycastle, L. L., Willer, C. J., Lyssenko, V., Shen, H., Kuusisto, J., Ebrahim, S., Sestu, N., Duren, W. L., Spada, M. C., Stringham, H. M. & 31 others, , 2008, In: Journal of Clinical Investigation. 118, 7, p. 2620-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A genomic mutational constraint map using variation in 76,156 human genomes
Chen, S., Francioli, L. C., Goodrich, J. K., Collins, R. L., Kanai, M., Wang, Q., Alföldi, J., Watts, N. A., Vittal, C., Gauthier, L. D., Poterba, T., Wilson, M. W., Tarasova, Y., Phu, W., Grant, R., Yohannes, M. T., Koenig, Z., Farjoun, Y., Banks, E., Donnelly, S. & 18 others, , 2024, In: Nature. 625, 7993, p. 92-100 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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The isoenzyme pattern of LDH does not play a physiological role; except perhaps during fast transitions in energy metabolism
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