Novo Nordisk Foundation Center for Basic Metabolic Research

  1. 2007
  2. Published

    Concentrations of the acute phase reactants high-sensitive C-reactive protein and YKL-40 and of interleukin-6 before and after treatment in patients with acromegaly and growth hormone deficiency

    Andreassen, Mikkel, drb459, drb459 & Kristensen, L. Ø., Dec 2007, In: Clinical Endocrinology. 67, 6, p. 909-16 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Bone resorption is decreased postprandially by intestinal factors and glucagon-like peptide-2 is a possible candidate

    Holst, Jens Juul, Hartmann, Bolette, Gottschalck, I. B., Jeppesen, Palle Bekker, Miholic, J. & Henriksen, D. B., Jul 2007, In: Scandinavian Journal of Gastroenterology. 42, 7, p. 814-20 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1α

    Gerhart-Hines, Zach, Rodgers, J. T., Bare, O., Lerin, C., Kim, S. H., Mostoslavsky, R., Alt, F. W., Wu, Z. & Puigserver, P., 4 Apr 2007, In: EMBO Journal. 26, 7, p. 1913-1923 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    The human PINK1 locus is regulated in vivo by a non-coding natural antisense RNA during modulation of mitochondrial function

    Schéele, Camilla Charlotte Nielsen, Petrovic, N., Faghihi, M. A., Lassmann, T., Fredriksson, K., Rooyackers, O., Wahlestedt, C., Good, L. & Timmons, J. A., 15 Mar 2007, In: BMC Genomics. 8, p. 74

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Disassociation of bone resorption and formation by GLP-2: a 14-day study in healthy postmenopausal women

    Henriksen, D. B., Alexandersen, P., Hartmann, Bolette, Adrian, C. L., Byrjalsen, I., Bone, H. G., Holst, Jens Juul & Christiansen, C., Mar 2007, In: Bone. 40, 3, p. 723-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Studies of the associations between functional beta2-adrenergic receptor variants and obesity, hypertension and type 2 diabetes in 7,808 white subjects

    Gjesing, A. P., Andersen, G., Burgdorf, Kristoffer Sølvsten, Borch-Johnsen, K., Jørgensen, T., Hansen, Torben & Pedersen, Oluf Borbye, Mar 2007, In: Diabetologia. 50, 3, p. 563-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    The Treeterbi and Parallel Treeterbi algorithms: efficient, optimal decoding for ordinary, generalized and pair HMMs.

    Keibler, E., Arumugam, Mani & Brent, M. R., Mar 2007, In: Bioinformatics. 23, 5, p. 545-554 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    A common haplotype in the G-protein-coupled receptor gene GPR74 is associated with leanness and increased lipolysis

    Dahlman, I., Dicker, A., Jiao, H., Kere, J., Blomqvist, L., van Harmelen, V., Hoffstedt, J., Borch-Johnsen, K., Jorgensen, T., Hansen, Torben, Pedersen, Oluf Borbye, Laakso, M. & Arner, P., 2007, In: American Journal of Human Genetics. 80, 6, p. 1115-24 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    A variant in CDKAL1 influences insulin response and risk of type 2 diabetes

    Steinthorsdottir, V., Thorleifsson, G., Reynisdottir, I., Benediktsson, R., Jonsdottir, T., Walters, G. B., Styrkarsdottir, U., Gretarsdottir, S., Emilsson, V., Ghosh, S., Baker, A., Snorradottir, S., Bjarnason, H., Ng, M. C. Y., Hansen, T., Bagger, Y., Wilensky, R. L., Reilly, M. P., Adeyemo, A., Chen, Y. & 25 others, Zhou, J., Gudnason, V., Chen, G., Huang, H., Lashley, K., Doumatey, A., So, W., Ma, R. C. Y., Andersen, G., Borch-Johnsen, K., Jorgensen, T., van Vliet-Ostaptchouk, J. V., Hofker, M. H., Wijmenga, C., Christiansen, C., Rader, D. J., Rotimi, C., Gurney, M., Chan, J. C. N., Pedersen, Oluf Borbye, Sigurdsson, G., Gulcher, J. R., Thorsteinsdottir, U., Kong, A. & Stefansson, K., 2007, In: Nature Genetics. 39, 6, p. 770-5 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    AS160 phosphorylation is associated with activation of alpha(2)beta(2)gamma(1)- but not alpha(2)beta(2)gamma(3)-AMPK trimeric complex in skeletal muscle during exercise in humans

    Treebak, Jonas Thue, Birk, Jesper Bratz, Rose, A. J., Kiens, Bente, Richter, Erik A. & Wojtaszewski, Jørgen F P, 2007, In: American Journal of Physiology-Endocrinology and Metabolism.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Association between obesity and asthma in a twin cohort

    Thomsen, S., Ulrik, Charlotte Suppli, Kyvik, K., Sørensen, Thorkild I.A., Posthuma, D., Skadhauge, L., Steffensen, I. & Backer, V., 2007, In: Allergy. European Journal of Allergy and Clinical Immunology. 62, 10, p. 1199-1204 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Common variation in LMNA increases susceptibility to type 2 diabetes and associates with elevated fasting glycemia and estimates of body fat and height in the general population: studies of 7,495 Danish whites

    Wegner, L., Andersen, G., Sparsø, T., Grarup, N., Glümer, C., Borch-Johnsen, K., Jørgensen, T., Hansen, Torben & Pedersen, Oluf Borbye, 2007, In: Diabetes. 56, 3, p. 694-8 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Genetic analysis of the estrogen-related receptor alpha and studies of association with obesity and type 2 diabetes

    Larsen, L. H., Rose, C. S., Sparsø, T., Overgaard, J., Torekov, Signe Sørensen, Grarup, N., Jensen, Dan Funck, Albrechtsen, Anders, Andersen, G., Ek, J., Glümer, C., Borch-Johnsen, K., Jørgensen, Tina, Hansen, Teis Schjals & Pedersen, Oluf Borbye, 2007, In: International Journal of Obesity. 31, 2, p. 365-70 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Glucagon-like peptide-2 in umbilical cord blood from mature infants

    Bodé, S., Hartmann, Bolette, Holst, Jens Juul & Greisen, Gorm, 2007, In: Neonatology. 91, 1, p. 49-53 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Hyperphosphorylation and low protein content of muscle glycogen synthase contribute to insulin resistance in polycystic ovary syndrome: effects of pioglitazone treatment

    Hojlund, K., Glintborg, D., Andersen, N. R., Birk, Jesper Bratz, Treebak, Jonas Thue, Beck-Nielsen, H. & Wojtaszewski, Jørgen F P, 2007, In: Diabetologia.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Phenoxyacetic acid derivatives as CRTH2 receptor ligands, their preparation, pharmaceutical compositions, and use in therapy

    Ulven, Trond, Frimurer, Thomas Michael, Rist, Ø., Kostenis, E., Högberg, T., Receveur, J. & Grimstrup, M., 2007, Patent No. WO 2007/062678 A1

    Research output: Patent

  18. Published
  19. Published

    Pointwise and Genomewide Significance Calculations in Gene Mapping through Nonparametric Linkage Analysis: Theory, Algorithms and Applications (Summary)

    Ängquist, Lars, 2007, In: Qvartilen. 22, 2, p. 25-26

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Polymorphisms in the 3' UTR in the neurocalcin delta gene affect mRNA stability, and confer susceptibility to diabetic nephropathy

    Kamiyama, M., Kobayashi, M., Araki, S., Iida, A., Tsunoda, T., Kawai, K., Imanishi, M., Nomura, M., Babazono, T., Iwamoto, Y., Kashiwagi, A., Kaku, K., Kawamori, R., Ng, D. P. K., Hansen, Torben, Gaede, P., Pedersen, Oluf Borbye, Nakamura, Y. & Maeda, S., 2007, In: Human Genetics. 122, 3-4, p. 397-407 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Porcine glucagon-like peptide-2: structure, signaling, metabolism and effects

    Pedersen, N. B., Hjøllund, K. R., Johnsen, A. H., Ørskov, Cathrine, Rosenkilde, Mette, Hartmann, B. & Holst, Jens Juul, 2007, In: Regulatory Peptides. 146, 1-3, p. 310-320 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Porcine transcriptome analysis based on 97 non-normalized cDNA libraries and assembly of 1,021,891 expressed sequence tags

    Gorodkin, J., Cirera, S., Hedegaard, J., Gilchrist, M. J., Panitz, F., Jørgensen, C., Scheibye-Knudsen, K., Arvin, T., Lumholdt, S., Sawera, M., Green, T., Nielsen, B., Havgaard, J. H., Rosenkilde, C., Wang, J., Li, H., Li, R., Liu, B., Hu, S., Dong, W. & 16 others, Li, W., Yu, J., Wang, J., Staefeldt, H., Wernersson, R., Madsen, L. B., Thomsen, B. S., Hornshøj, H., Bujie, Z., Wang, X., Wang, X., Bolund, L., Brunak, Søren, Yang, H., Bendixen, C. & Fredholm, Merete, 2007, In: Genome Biology. 8, R45, p. R45 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution

    Helgason, A., Pálsson, S., Thorleifsson, G., Grant, S. F. A., Emilsson, V., Gunnarsdottir, S., Adeyemo, A., Chen, Y., Chen, G., Reynisdottir, I., Benediktsson, R., Hinney, A., Hansen, T., Andersen, G., Borch-Johnsen, K., Jorgensen, T., Schäfer, H., Faruque, M., Doumatey, A., Zhou, J. & 13 others, Wilensky, R. L., Reilly, M. P., Rader, D. J., Bagger, Y., Christiansen, C., Sigurdsson, G., Hebebrand, J., Pedersen, Oluf Borbye, Thorsteinsdottir, U., Gulcher, J. R., Kong, A., Rotimi, C. & Stefánsson, K., 2007, In: Nature Genetics. 39, 2, p. 218-25 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Relationships between the functional PPARalpha Leu162Val polymorphism and obesity, type 2 diabetes, dyslipidaemia, and related quantitative traits in studies of 5799 middle-aged white people

    Sparsø, T., Hussain, M. S., Andersen, G., Hainerova, I., Borch-Johnsen, K., Jørgensen, T., Hansen, Torben & Pedersen, Oluf Borbye, 2007, In: Molecular Genetics and Metabolism. 90, 2, p. 205-9 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Rosiglitazone monotherapy for type 2 diabetes mellitus-too soon to ADOPT?

    Gaede, P. & Pedersen, Oluf Borbye, 2007, In: Nature clinical practice. Endocrinology & metabolism. 3, 6, p. 456-7 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Studies of association of the CASQ1 rs2275703 polymorphism in relation to type 2 diabetes and related quantitative metabolic traits among 7,088 Danish whites

    Sparsø, T., Hussain, M. S., Borch-Johnsen, K., Jørgensen, T., Madsbad, Sten, Hansen, Torben, Pedersen, Oluf Borbye & Andersen, G., 2007, In: Molecular Genetics and Metabolism. 92, 3, p. 278-282 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review