- Published
Structure-based discovery of novel US28 small molecule ligands with different modes of action
Lückmann, Michael, Amarandi, R., Papargyri, N., Jakobsen, M. H., Ulven, Elisabeth Rexen, Jensen, Lars Juhl, Pui, A., Schwartz, Thue W., Rosenkilde, Mette & Frimurer, Thomas Michael, 2017, In: Chemical Biology & Drug Design. 89, 3, p. 289–296Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structure-Activity Studies of 3,9-Diazaspiro[5.5]undecane-Based ?-Aminobutyric Acid Type A Receptor Antagonists with Immunomodulatory Effect
Bavo, Francesco, De-Jong, H., Petersen, Jonas Odgaard, Falk-Petersen, C. B., Löffler, R., Sparrow, E., Rostrup, F., Eliasen, Jannik Nicklas, Wilhelmsen, K. S., Barslund, K., Bundgaard, C., Nielsen, Birgitte, Kristiansen, Uffe, Wellendorph, Petrine, Bogdanov, Y. & Frølund, Bente, 2021, In: Journal of Medicinal Chemistry. 64, 24, p. 17795-17812Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structure-Activity Relationships and Identification of Optmized CC-Chemokine Receptor CCR1, 5, and 8 Metal-Ion Chelators
Chalikiopoulos, A., Thiele, S., Malmgaard-Clausen, M., Rydberg, P., Isberg, V., Ulven, Trond, Frimurer, Thomas Michael, Rosenkilde, Mette & Gloriam, David E., 25 Nov 2013, In: Journal of Chemical Information and Modeling. 53, 11, p. 2863-73 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structure-Activity Investigations and Optimisations of Non-metabolite Agonists for the Succinate Receptor 1
Ulven, Elisabeth Rexen, Trauelsen, Mette, Brvar, M., Lückmann, Michael, Bielefeldt, L. Ø., Jensen, L. K. I., Schwartz, Thue W. & Frimurer, Thomas Michael, 2018, In: Scientific Reports. 8, 1, p. 1-18 10010.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structure and stability of the spinach aquaporin SoPIP2;1 in detergent micelles and lipid membranes
Plasencia, I., Survery, S., Ibragimova, S., Hansen, J. S., Kjellbom, P., Helix-Nielsen, C., Johanson, U. & Mouritsen, Ole G., 28 Feb 2011, In: PLoS ONE. 6, 2, e14674.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural elucidation of 3-nitrophenylhydrazine derivatives of tricarboxylic acid cycle acids and optimization of their fragmentation to boost sensitivity in liquid chromatography-mass spectrometry
Hodek, O., Henderson, John David, Argemi Muntadas, Lidia, Khan, Adnan & Moritz, Thomas, 2023, In: Journal of Chromatography - B. 1222, 9 p., 123719.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural characterization of the microbial enzyme urocanate reductase mediating imidazole propionate production
Venskutonytė, R., Koh, A., Stenström, O., Khan, M. T., Lundqvist, A., Akke, M., Bäckhed, F. & Lindkvist-Petersson, K., 2021, In: Nature Communications. 12, 1, 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural changes at the myrtenol backbone reverse its positive allosteric potential into inhibitory GABAA receptor modulation
Milanos, S., Kuenzel, K., Gilbert, D. F., Janzen, D., Sasi, M., Buettner, A., Frimurer, Thomas Michael & Villmann, C., 2018, In: Biological Chemistry. 399, 6, p. 549-563 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural biology: snapshot of a signalling complex.
Schwartz, Thue W. & Sakmar, T., Sep 2011, In: Nature.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural biology: Full monty of family B GPCRs
Schwartz, Thue W. & Frimurer, Thomas Michael, 2017, In: Nature Chemical Biology. 13, 8, p. 819-821Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural basis for constitutive activity and agonist-induced activation of the enteroendocrine fat sensor GPR119
Engelstoft, M. S., Norn, C., Pedersen, M. H., Holliday, N. D., Elster, L., Lehmann, J., Jones, R. M., Frimurer, Thomas Michael & Schwartz, Thue W., Dec 2014, In: British Journal of Pharmacology. 171, 24, p. 5774-89 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural basis for GPCR signaling by small polar versus large lipid metabolites-discovery of non-metabolite ligands
Lückmann, Michael, Trauelsen, Mette, Frimurer, Thomas Michael & Schwartz, Thue W., 2020, In: Current Opinion in Cell Biology. 63, p. 38-48Research output: Contribution to journal › Review › Research › peer-review
- Published
Structural and functional development of small intestine in intrauterine growth retarded porcine offspring born to gilts fed diets with differing protein ratios throughout pregnancy
Mickiewicz, M., Zabielski, R., Grenier, B., Le Normand, L., Savary, G., Holst, Jens Juul, Oswald, I. P., Metges, C. C. & Guilloteau, P., 2012, In: Journal of Physiology and Pharmacology. 63, 3, p. 225-39 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Strong protective effect of the APOL1 p.N264K variant against G2-associated focal segmental glomerulosclerosis and kidney disease
Gupta, Y., Friedman, D. J., McNulty, M. T., Khan, A., Lane, B., Wang, C., Ke, J., Jin, G., Wooden, B., Knob, A. L., Lim, T. Y., Appel, G. B., Huggins, K., Liu, L., Mitrotti, A., Stangl, M. C., Bomback, A., Westland, R., Bodria, M., Marasa, M. & 60 others, , 2023, In: Nature Communications. 14, 8 p., 7836.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stress hormone release is a key component of the metabolic response to lipopolysaccharide (LPS): studies in hypopituitary and healthy subjects
Bach, E., Møller, A. B., Jorgensen, J. O. L., Vendelbo, M. H., Jessen, N., Pedersen, S. B., Nielsen, Thomas Svava & Møller, N., 25 Aug 2016, In: European Journal of Endocrinology. 175, 5, p. 455-465 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Strenuous physical exercise adversely affects monocyte chemotaxis
Czepluch, F. S., Barrès, Romain, Caidahl, K., Olieslagers, S., Krook, A., Rickenlund, A., Zierath, Juleen R & Waltenberger, J., Jan 2011, In: Thrombosis and Haemostasis. 105, 1, p. 122-30 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stratification by smoking status reveals an association of CHRNA5-A3-B4 genotype with body mass index in never smokers
Taylor, A. E., Morris, R. W., Fluharty, M. E., Bjorngaard, J. H., Åsvold, B. O., Gabrielsen, M. E., Campbell, A., Marioni, R., Kumari, M., Hällfors, J., Männistö, S., Marques-Vidal, P., Kaakinen, M., Cavadino, A., Postmus, I., Husemoen, L. L. N., Skaaby, T., Ahluwalia, T. V. S., Treur, J. L., Willemsen, G. & 44 others, , Dec 2014, In: P L o S Genetics. 10, 12, p. 1-6 6 p., e1004799.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Strategies for conditional two-locus nonparametric linkage analysis
Ängquist, Lars, Hössjer, O. & Groop, L., 1 Jul 2008, In: Human Heredity. 66, 3, p. 138-156 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stool energy density is positively correlated to intestinal transit time and related to microbial enterotypes
Boekhorst, J., Venlet, N., Procházková, Nicola, Hansen, M. L., Lieberoth, C. B., Bahl, M. I., Lauritzen, Lotte, Pedersen, Oluf Borbye, Licht, T. R., Kleerebezem, M. & Roager, Henrik Munch, 2022, In: Microbiome. 10, 10 p., 223.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stone Age “chewing gum” yields 5,700 yearold human genome and oral microbiome
Jensen, Theis Zetner Trolle, Niemann, Jonas, Iversen, K. H., Fotaki, Anna Katerina, Gopalakrishan, S., Sinding, Mikkel Holger Strander, Ellegaard, M. R., Allentoft, Morten Erik, Lanigan, Liam Thomas, Taurozzi, Alberto John, Nielsen, Sofie Holtsmark, Dee, M. W., Mortensen, M. N., Christensen, M. C., Sørensen, S. A., Collins, Matthew James, Gilbert, M Thomas P, Sikora, Martin, Rasmussen, Simon & Schroeder, Hannes, 2018, bioRxiv, 32 p.Research output: Working paper › Preprint › Research
- Published
Stimulation of the Bile Acid Receptor Tgr5 Promotes Intestinal Growth
Dal, Jenna Elizabeth Hunt, Hartmann, Bolette, Ullmer, C., Holst, Jens Juul & Kissow, Hannelouise, 1 May 2018, In: Gastroenterology. 154, 6 (S1), 1 p., S-333.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Stimulation of intestinal growth and function with DPP-IV inhibition in a mouse short bowel syndrome model
Sueyoshi, R., Ignatoski, K. M. W., Okawada, M., Hartmann, Bolette, Holst, Jens Juul & Teitelbaum, D. H., 26 Jun 2014, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 307, 4, p. G410-19 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Steroid-induced insulin resistance and impaired glucose tolerance are both associated with a progressive decline of incretin effect in first-degree relatives of patients with type 2 diabetes
Jensen, D. H., Aaboe, K., Henriksen, J. E., Vølund, A., Holst, Jens Juul, Madsbad, Sten & Krarup, T., 2012, In: Diabetologia. 55, 5, p. 1406-16 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Steno-2-studiet: intensiv multifaktoriel behandling reducerer forekomsten af kardiovaskulaer sygdom hos patienter med type 2-diabetes
Gaede, P. H., Jepsen, P. V., Larsen, J. N. B., Jensen, G. V., Parving, H. & Pedersen, Oluf Borbye, 2003, In: Ugeskrift for Laeger. 165, 26, p. 2658-61 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stella modulates transcriptional and endogenous retrovirus programs during maternal-to-zygotic transition
Huang, Yun, Kim, J. K., Do, D. V., Lee, C., Penfold, C. A., Zylicz, Jan Jakub, Marioni, J. C., Hackett, J. A. & Surani, M. A., 21 Mar 2017, In: eLife. 6, e22345.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Staying strong during hibernation
Sommer, F. & Bäckhed, F., 2022, In: Science. 375, 6579, p. 376-377 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Statins for cirrhosis: almost ready for clinical application
Kimer, N., Kronborg, T. M., Bendtsen, Flemming & Møller, Søren, 2020, In: Digestive Medicine Research. 3, 4 p., 111.Research output: Contribution to journal › Editorial › Research
- Published
Statins are independently associated with increased HbA1c in type 1 diabetes: The Thousand & 1 Study
Jensen, M. T., Andersen, H. U., Rossing, Peter & Jensen, J. S., Jan 2016, In: Diabetes Research and Clinical Practice. 111, p. 51–57Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Statin therapy is associated with lower prevalence of gut microbiota dysbiosis
Vieira-Silva, S., Falony, G., Belda, E., Nielsen, T., Aron-Wisnewsky, J., Chakaroun, R., Forslund, S. K., Assmann, K., Valles-Colomer, M., Nguyen, T. T. D., Proost, S., Prifti, E., Tremaroli, V., Pons, N., Le Chatelier, E., Andreelli, F., Bastard, J-P., Coelho, L. P., Galleron, N., Hansen, T. H. & 28 others, , 2020, In: Nature. 581, 7808, p. 310-315Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stata tip 92: Manual implementation of permutations and bootstraps
Ängquist, Lars, 1 Dec 2010, In: Stata Journal. 10, 4, p. 686-688 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stata tip 117: graph combine-Combining graphs
Ängquist, Lars, 2014, In: Stata Journal. 14, 1, p. 221-225Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Standard procedures for blood withdrawal in conscious male rats induce stress and profoundly affect glucose tolerance and secretion of glucoregulatory hormones
Pedersen, K., Andersen, H., Fledelius, C., Holst, Jens Juul, Hjuler, S. T. & Kuhre, Rune Ehrenreich, 2023, In: Molecular Metabolism. 69, 101689.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stable intergenerational associations of childhood overweight during the development of the obesity epidemic
Ajslev, T. A., Ängquist, Lars, Silventoinen, K., Baker, J. L. & Sørensen, Thorkild I.A., Jun 2015, In: Obesity. 23, 6, p. 1279-87 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stability of the Associations between Early Life Risk Indicators and Adolescent Overweight over the Evolving Obesity Epidemic
Graversen, L., Sørensen, Thorkild I.A., Petersen, L., Sovio, U., Kaakinen, M., Sandbæk, A., Laitinen, J., Taanila, A., Pouta, A., Järvelin, M. & Obel, C., 2014, In: PLOS ONE. 9, 4, p. 1-9 9 p., e95314.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stability of glucagon-like peptide-1 and glucagon in human plasma
Albrechtsen, Nicolai Jacob Wewer, Bak, M. J., Hartmann, Bolette, Christensen, L. W., Kuhre, Rune Ehrenreich, Deacon, Carolyn F. & Holst, Jens Juul, 16 Jan 2015, In: Endocrine Connections. 4, 1, p. 50-57 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Squeezing Flux Out of Fat
Gonzalez-Franquesa, A. & Patti, M., 2018, In: Trends in Endocrinology and Metabolism. 29, 4, p. 201-202Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spinal astroglial cannabinoid receptors control pathological tremor
Carlsen, Eva Maria Meier, Falk, S., Skupio, U., Robin, L., Zottola, A. C. P., Marsicano, G. & Perrier, Jean-Francois Marie, 2021, In: Nature Neuroscience. 24, p. 658–666 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sphingolipids Are Depleted in Alcohol-Related Liver Fibrosis
Thiele, M., Suvitaival, T., Trošt, K., Kim, M., de Zawadzki, A., Kjaergaard, M., Rasmussen, D. N., Lindvig, K. P., Israelsen, M., Detlefsen, S., Andersen, P., Juel, H. B., Nielsen, T., Georgiou, S., Filippa, V., Kuhn, M., Nishijima, S., Moitinho-Silva, L., Rossing, P., Trebicka, J. & 14 others, , 2023, In: Gastroenterology. 164, 7, p. 1248-1260Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sperm epigenetics and influence of environmental factors
Donkin, I. & Barrès, Romain, 2018, In: Molecular Metabolism. 14, p. 1-11 11 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Sperm count is increased by diet-induced weight loss and maintained by exercise or GLP-1 analogue treatment: a randomized controlled trial
Andersen, E., Juhl, C. R., Kjøller, E. T., Lundgren, J. R., Janus, C., Dehestani, Y., Saupstad, M., Ingerslev, L. R., Duun, O. M., Jensen, Simon Birk Kjær, Holst, Jens Juul, Stallknecht, Bente Merete, Madsbad, Sten, Torekov, Signe Sørensen & Barrès, Romain, May 2022, In: Human Reproduction. 37, 7, p. 1414–1422 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Specificity and sensitivity of commercially available assays for glucagon-like peptide-1 (GLP-1): Implications for GLP-1 measurements in clinical studies
Bak, M. J., Albrechtsen, Nicolai Jacob Wewer, Pedersen, Jens, Knop, Filip Krag, Vilsbøll, Tina, Jørgensen, N. B., Hartmann, Bolette, Deacon, Carolyn F., Dragsted, Lars Ove & Holst, Jens Juul, 2014, In: Diabetes, Obesity and Metabolism. 16, 11, p. 1155-1164 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Specificity and sensitivity of commercially available assays for glucagon and oxyntomodulin measurement in humans
Bak, M. J., Albrechtsen, Nicolai Jacob Wewer, Pedersen, Jens, Hartmann, Bolette, Christensen, M., Vilsbøll, T., Knop, F. K., Deacon, Carolyn F., Dragsted, Lars Ove & Holst, Jens Juul, 2014, In: European Journal of Endocrinology. 170, 4, p. 529-538 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Specific synbiotics in early life protect against diet-induced obesity in adult mice
Mischke, M., Arora, Tulika, Tims, S., Engels, E., Sommer, N., van Limpt, K., Baars, A., Oozeer, R., Oosting, A., Bäckhed, F. & Knol, J., 2018, In: Diabetes, Obesity and Metabolism. 20, 6, p. 1408-1418 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Specific inhibition of bile acid transport alters plasma lipids and GLP-1
Rudling, M., Camilleri, M., Graffner, H., Holst, Jens Juul & Rikner, L., 2015, In: B M C Cardiovascular Disorders. 15, p. 1-8 8 p., 75.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Specific gut microbiota features and metabolic markers in postmenopausal women with obesity
Brahe, L. K., Le Chatelier, E., Prifti, E., Pons, N., Kennedy, S., Hansen, Torben, Pedersen, Oluf Borbye, Astrup, A., Ehrlich, S. D. & Larsen, L. H., 15 May 2015, In: Nutrition and Diabetes. 5, 7 p., e159.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Specific and nonspecific responses to Plasmodium falciparum blood-stage parasites and observations on the gametocytemia in schoolchildren living in a malaria-endemic area of Mozambique
Høgh, Birthe, Thompson, R., Hetzel, C., Fleck, S. L., Kruse, N. A., Jones, I., Dgedge, M., Barreto, J. & Sinden, R. E., Jan 1995, In: American Journal of Tropical Medicine and Hygiene. 52, 1, p. 50-9 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Species-specific action of (Pro3)GIP - an efficacious agonist on human GIP receptor, but partial agonist and competitive antagonist on rat and mouse GIP receptors
wbf943, wbf943, Gasbjerg, Lærke Smidt, Svendsen, B., Christensen, M., Knop, Filip Krag, Hartmann, Bolette, Holst, Jens Juul & Rosenkilde, Mette, Jan 2016, In: British Journal of Pharmacology. 173, 1, p. 27-38 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spatially distributed encoding of covert attentional shifts in human thalamus
Hulme, O. J., Whiteley, Louise & Shipp, S., 2010, In: Journal of Neurology & Neurophysiology. 104, 6, p. 3644-56 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spatial consequences of bridging the saccadic gap
Yarrow, K., Whiteley, Louise, Rothwell, J. C. & Haggard, P., 2006, In: Vision Research. 46, 4, p. 545-55 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spatial QRS-T angle variants for prediction of all-cause mortality
Kück, K., Isaksen, Jonas L., Graff, C., Skaaby, T., Linneberg, Allan René, Hansen, Torben & Kanters, Jørgen K., 2018, In: Journal of Electrocardiology. 51, 5, p. 768-775 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity
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Determinants of plasma levels of proglucagon and the metabolic impact of glucagon receptor signalling: a UK Biobank study
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