Novo Nordisk Foundation Center for Basic Metabolic Research

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  1. Published

    The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

    Ehret, G. B., Ferreira, T., Chasman, D. I., Jackson, A. U., Schmidt, E. M., Johnson, T., Thorleifsson, G., Luan, J., Donnelly, L. A., Kanoni, S., Petersen, A-K., Pihur, V., Strawbridge, R. J., Shungin, D., Hughes, M. F., Meirelles, O., Kaakinen, M., Bouatia-Naji, N., Kristiansson, K., Shah, S. & 31 others, Kleber, M. E., Guo, X., Lyytikäinen, L., Fava, C., Eriksson, N., Nolte, I. M., Magnusson, P. K., Salfati, E. L., Rallidis, L. S., Theusch, E., Smith, A. J. P., Folkersen, L., Witkowska, K., Pers, Tune H, Joehanes, R., Kim, S. K., Lataniotis, L., Jansen, R., Johnson, A. D., Warren, H., Kim, Y. J., Zhao, W., Wu, Y., Tayo, B. O., Bochud, M., Absher, D., Adair, L. S., Amin, N., Njølstad, I., Schwarz, Peter & CHARGE-EchoGen Consortium, C. C., 12 Sep 2016, In: Nature Genetics. 48, 10, p. 1171-1184 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    The genetic history of Greenlandic-European contact

    Waples, R. K., Hauptmann, A. L., Seiding, I. H., Jørsboe, E., Jørgensen, M. E., Grarup, N., Andersen, M. K., Larsen, C. V. L., Bjerregaard, P., Hellenthal, G., Hansen, Torben, Albrechtsen, Anders & Moltke, Ida, 2021, In: Current Biology. 31, 10, p. 2214-2219.e4

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    The genetic architecture of type 2 diabetes

    Fuchsberger, C., Flannick, J., Teslovich, T. M., Mahajan, A., Agarwala, V., Gaulton, K. J., Ma, C., Fontanillas, P., Moutsianas, L., McCarthy, D. J., Rivas, M. A., Perry, J. R. B., Sim, X., Blackwell, T. W., Robertson, N. R., Rayner, N. W., Cingolani, P., Locke, A. E., Fernandez Tajes, J., Highland, H. M. & 281 others, Dupuis, J., Chines, P. S., Lindgren, C. M., Hartl, C., Jackson, A. U., Chen, H., Huyghe, J. R., van de Bunt, M., Pearson, R. D., Kumar, A., Müller-Nurasyid, M., Grarup, N., Stringham, H. M., Gamazon, E. R., Lee, J., Chen, Y., Scott, R. A., Below, J. E., Chen, P., Huang, J., Go, M. J., Stitzel, M. L., Pasko, D., Parker, S. C. J., Varga, T. V., Green, T., Beer, N. L., Day-Williams, A. G., Ferreira, T., Fingerlin, T., Horikoshi, M., Hu, C., Huh, I., Ikram, M. K., Kim, B., Kim, Y., Kim, Y. J., Kwon, M., Lee, J., Lee, S., Lin, K., Maxwell, T. J., Nagai, Y., Wang, X., Welch, R. P., Yoon, J., Zhang, W., Barzilai, N., Voight, B. F., Han, B., Jenkinson, C. P., Kuulasmaa, T., Kuusisto, J., Manning, A., Ng, M. C. Y., Palmer, N. D., Balkau, B., Stancáková, A., Abboud, H. E., Boeing, H., Giedraitis, V., Prabhakaran, D., Gottesman, O., Scott, J., Carey, J., Kwan, P., Grant, G., Smith, J. D., Neale, B. M., Purcell, S., Butterworth, A. S., Howson, J. M. M., Lee, H. M., Lu, Y., Kwak, S., Zhao, W., Danesh, J., Lam, V. K. L., Park, K. S., Saleheen, D., So, W. Y., Tam, C. H. T., Afzal, U., Aguilar, D., Arya, R., Aung, T., Chan, E., Navarro, C., Cheng, C., Palli, D., Correa, A., Curran, J. E., Rybin, D., Farook, V. S., Fowler, S. P., Freedman, B. I., Griswold, M., Hale, D. E., Hicks, P. J., Khor, C., Kumar, S., Lehne, B., Thuillier, D., Lim, W. Y., Liu, J., van der Schouw, Y. T., Loh, M., Musani, S. K., Puppala, S., Scott, W. R., Yengo, L., Tan, S., Taylor, H. A., Thameem, F., Wilson, G., Wong, T. Y., Njølstad, P. R., Levy, J. C., Mangino, M., Bonnycastle, L. L., Schwarzmayr, T., Fadista, J., Surdulescu, G. L., Herder, C., Groves, C. J., Wieland, T., Bork-Jensen, J., Brandslund, I., Christensen, C., Koistinen, H. A., Doney, A. S. F., Kinnunen, L., Esko, T., Farmer, A. J., Hakaste, L., Hodgkiss, D., Kravic, J., Lyssenko, V., Hollensted, M., Jørgensen, M. E., Jørgensen, T., Ladenvall, C., Justesen, Johanne Marie, Käräjämäki, A., Kriebel, J., Rathmann, W., Lannfelt, L., Lauritzen, T., Narisu, N., Linneberg, Allan René, Melander, O., Milani, L., Neville, M., Orho-Melander, M., Qi, L., Qi, Q., Roden, M., Rolandsson, O., Swift, A., Rosengren, A. H., Stirrups, K., Wood, A. R., Mihailov, E., Blancher, C., Carneiro, M. O., Maguire, J., Poplin, R., Shakir, K., Fennell, T., DePristo, M., Hrabé de Angelis, M., Deloukas, P., Gjesing, A. P., Jun, G., Nilsson, P., Murphy, J., Onofrio, R., Thorand, B., Hansen, Torben, Meisinger, C., Hu, F. B., Isomaa, B., Karpe, F., Liang, L., Peters, A., Huth, C., O'Rahilly, S. P., Palmer, C. N. A., Pedersen, Oluf Borbye, Rauramaa, R., Tuomilehto, J., Salomaa, V., Watanabe, R. M., Syvänen, A., Bergman, R. N., Bharadwaj, D., Bottinger, E. P., Cho, Y. S., Chandak, G. R., Chan, J. C. N., Chia, K. S., Daly, M. J., Ebrahim, S. B., Langenberg, C., Elliott, P., Jablonski, K. A., Lehman, D. M., Jia, W., Ma, R. C. W., Pollin, T. I., Sandhu, M., Tandon, N., Froguel, P., Barroso, I., Teo, Y. Y., Zeggini, E., Loos, R. J. F., Small, K. S., Ried, J. S., DeFronzo, R. A., Grallert, H., Glaser, B., Metspalu, A., Wareham, N. J., Walker, M., Banks, E., Gieger, C., Ingelsson, E., Im, H. K., Illig, T., Franks, P. W., Buck, G., Trakalo, J., Buck, D., Prokopenko, I., Mägi, R., Lind, L., Farjoun, Y., Owen, K. R., Gloyn, A. L., Strauch, K., Tuomi, T., Kooner, J. S., Lee, J., Park, T., Donnelly, P., Morris, A. D., Hattersley, A. T., Bowden, D. W., Collins, F. S., Atzmon, G., Chambers, J. C., Spector, T. D., Laakso, M., Strom, T. M., Bell, G. I., Blangero, J., Duggirala, R., Tai, E. S., McVean, G., Hanis, C. L., Wilson, J. G., Seielstad, M., Frayling, T. M., Meigs, J. B., Cox, N. J., Sladek, R., Lander, E. S., Gabriel, S., Burtt, N. P., Mohlke, K. L., Meitinger, T., Groop, L., Abecasis, G., Florez, J. C., Scott, L. J., Morris, A. P., Kang, H. M., Boehnke, M., Altshuler, D. & McCarthy, M. I., 4 Aug 2016, In: Nature. 536, 7614, p. 41-47 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    The genetic and environmental influences on childhood obesity: a systematic review of twin and adoption studies

    Silventoinen, K., Rokholm, B., Kaprio, J. & Sørensen, Thorkild I.A., 1 Jan 2010, In: International Journal of Obesity. 34, 1, p. 29-40 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    The gastric acid secretagogue gastrin-releasing peptide and the inhibitor oxyntomodulin do not exert their effect directly on the parietal cell in the rat

    Poulsen, Steen Seier & Holst, Jens Juul, 1988, In: Digestion. 40, 3, p. 144-51 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    The functional Thr130Ile and Val255Met polymorphisms of the hepatocyte nuclear factor-4alpha (HNF4A): gene associations with type 2 diabetes or altered beta-cell function among Danes

    Ek, J., Rose, C. S., Jensen, D. P., Glümer, C., Borch-Johnsen, K., Jørgensen, T., Pedersen, Oluf Borbye & Hansen, Torben, 2005, In: Journal of Clinical Endocrinology and Metabolism. 90, 5, p. 3054-9 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    The functional Pro129Thr variant of the FAAH gene is not associated with various fat accumulation phenotypes in a population-based cohort of 5,801 whites

    Jensen, D. P., Lepola, Mette Andersen, Hansen, L., Eiberg, Hans Rudolf Lytchoff, Borch-Johnsen, K., Jørgensen, T., Hansen, Torben, Pedersen, Oluf Borbye & Andreasen, C. H., 2007, In: Journal of Molecular Medicine. 85, 5, p. 445-9 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    The frequent UCP2 -866G>A polymorphism protects against insulin resistance and is associated with obesity: a study of obesity and related metabolic traits among 17¿636 Danes

    Andersen, G., Dalgaard, L. T., Justesen, Johanne Marie, Anthonsen, S., Nielsen, T., Thørner, L. W., Witte, D., Jørgensen, T., Clausen, J. O., Lauritzen, T., Holmkvist, J., Hansen, Torben & Pedersen, Oluf Borbye, 2012, In: International Journal of Obesity.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    The expression of four pyridoxal kinase (PDXK) human variants in Drosophila impacts on genome integrity

    Mascolo, E., Barile, A., Mecarelli, L. S., Amoroso, N., Merigliano, C., Massimi, A., Saggio, I., Hansen, Torben, Tramonti, A., Di Salvo, M. L., Barbetti, F., Contestabile, R. & Verni, F., 2019, In: Scientific Reports. 9, 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    The expanding incretin universe: from basic biology to clinical translation

    Drucker, D. J. & Holst, Jens Juul, 2023, In: Diabetologia. 66, p. 1765-1779

    Research output: Contribution to journal › Review › Research › peer-review

  11. Published

    The exercise-induced long noncoding RNA CYTOR promotes fast-twitch myogenesis in aging

    Wohlwend, M., Laurila, P., William, K., Romani, M., Lima, T., Pattawaran, P., Benegiamo, G., Salonen, M., Schneider, B. L., Lahti, J., Eriksson, J. G., Barrès, Romain, Wisloff, U., Moreira, José & Auwerx, J., 2021, In: Science Translational Medicine. 13, 623, 14 p., eabc7367.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    The exaggerated glucagon-like peptide-1 response is important for the improved β-cell function and glucose tolerance after Roux-en-Y gastric bypass in patients with type 2 diabetes

    Jørgensen, N. B., Dirksen, C., Bojsen-Møller, K. N., Jacobsen, S. H., Worm, Dorte, Hansen, D. L., Kristiansen, V. B., Naver, L., Madsbad, Sten & Holst, Jens Juul, 6 May 2013, In: Diabetes. 62, 9, p. 3044-3052 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    The energy balance model of obesity: beyond calories in, calories out

    Hall, K. D., Farooqi, I. S., Friedman, J. M., Klein, S., Loos, Ruth, Mangelsdorf, D. J., O'Rahilly, S., Ravussin, E., Redman, L. M., Ryan, D. H., Speakman, J. R. & Tobias, D. K., 2022, In: American Journal of Clinical Nutrition. 115, 5, p. 1243-1254 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    The effects of soy isoflavones on obesity

    Ørgaard, A. & Jensen, L., 5 Jun 2008, In: Experimental Biology and Medicine (Maywood). 233, 9, p. 1066-80 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    The effects of laparoscopic Roux-en-Y gastric bypass and one-anastomosis gastric bypass on glycemic control and remission of type 2 diabetes mellitus: study protocol for a multi-center randomized controlled trial (the DIABAR-trial)

    van Rijswijk, A., van Olst, N., Meijnikman, A. S., Acherman, Y. I. Z., Bruin, S. C., van de Laar, A. W., van Olden, C. C., Aydin, O., Borger, H., Beuers, U. H. W., Herrema, H., Verheij, J., Apers, J. A., Bäckhed, F., Gerdes, V. E. A., Nieuwdorp, M. & de Brauw, L. M., 2022, In: Trials. 23, 12 p., 900.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    The effects of dual GLP-1/GIP receptor agonism on glucagon secretion: a review

    Mathiesen, D. S., Bagger, J. I., Bergmann, N. C., Lund, A., Christensen, Mikkel Bring, Vilsbøll, Tina & Knop, Filip Krag, 2019, In: International Journal of Molecular Sciences. 20, 17, 18 p., 4092.

    Research output: Contribution to journal › Review › Research › peer-review

  17. Published

    The effects of adding group-based lifestyle counselling to individual counselling on changes in plasma glucose levels in a randomized controlled trial: the Inter99 study

    Lau, C., Vistisen, D., Toft, U., Tetens, Inge , Glümer, C., Pedersen, Oluf Borbye, Jørgensen, T. & Borch-Johnsen, K., 2011, In: Diabetes & Metabolism. 37, 6, p. 546-52 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    The effects of a 2-year physical activity and dietary intervention on plasma lipid concentrations in children: the PANIC Study

    Eloranta, A-M., Sallinen, T., Viitasalo, A., Lintu, N., Väistö, J., Jalkanen, H., Tompuri, T. T., Soininen, S., Haapala, E. A., Kiiskinen, S., Schnurr, T. M., Kilpeläinen, T. O., Mikkonen, S., Savonen, K., Atalay, M., Brage, S., Laaksonen, D. E., Lindi, V., Ågren, J., Schwab, U. & 2 others, Jääskeläinen, J. & Lakka, T. A., 2021, In: European Journal of Nutrition. 60, p. 425-434

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    The effects of TNF-α on GLP-1-stimulated plasma glucose kinetics

    Lehrskov-Schmidt, L., Lehrskov-Schmidt, L., Nielsen, S. T., Holst, Jens Juul, Møller, K. & Solomon, T. P. J., Apr 2015, In: The Journal of clinical endocrinology and metabolism. 100, 4, p. E616-E622 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    The effects of L-arabinose on intestinal sucrase activity: dose-response studies in vitro and in humans

    Krog-Mikkelsen, I., Hels, O., Tetens, Inge , Holst, Jens Juul, Andersen, Jens Rikardt & Bukhave, K., 2011, In: American Journal of Clinical Nutrition. 94, 2, p. 472-478 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    The effects of 3 weeks of oral glutathione supplementation on whole body insulin sensitivity in obese males with and without type 2 diabetes: a randomized trial

    Søndergård, S. D., Cintin, I., Kuhlman, A. B., Morville, T. H., Bergmann, M. L., Kjær, L. K., Poulsen, Henrik Enghusen, Giustarini, D., Rossi, R., Dela, Flemming, Helge, Jørn Wulff & Larsen, S., 2021, In: Applied Physiology, Nutrition and Metabolism. 46, 9, 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    The effect of two frequent amino acid variants of the hepatocyte nuclear factor-1α gene on estimates of the pancreatic β-cell function in Caucasian glucosetolerant first-degree relatives of type 2 diabetic patients

    Urhammer, Søren Asger, Møller, Ann, Nyholm, B., Ekstrøm, Claus Thorn, Eiberg, Hans Rudolf Lytchoff, Clausen, J. O., Hansen, Torben, Pedersen, Oluf Borbye & Schmitz, O., 20 Nov 1998, In: Journal of Clinical Endocrinology and Metabolism. 83, 11, p. 3992-3995 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    The effect of traditional diet on glucose homeostasis in carriers and non-carriers of a common TBC1D4 variant in Greenlandic Inuit: A randomized crossover study

    Lewis, Jack Ivor, Lind, M. V., Møller, G., Hansen, Torben, Pedersen, H., Christensen, M. M. B., Laursen, J. C., Nielsen, S., Ottendahl, C. B., Larsen, C. V. L., Stark, K. D., Bjerregaard, P., Jørgensen, M. E. & Lauritzen, Lotte, 2023, In: British Journal of Nutrition. 130, 11, p. 1871-1884

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    The effect of sucrase-isomaltase deficiency on metabolism, food intake and preferences: protocol for a dietary intervention study

    Senftleber, N. K., Pedersen, K. S., Schnoor Jørgensen, C., Pedersen, H., Bjerg Christensen, M. M., Kabel Madsen, E., Andersen, K., Jørsboe, E., Gillum, M. P., Frøst, Michael Bom, Hansen, Torben & Jørgensen, M. E., 2023, In: International Journal of Circumpolar Health. 82, 1, 10 p., 2178067.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    The effect of splenectomy on immunity to Plasmodium malariae and P. falciparum in a malaria immune donor

    Petersen, E., Høgh, Birthe, Marbiah, N. T. & Hanson, A. P., Mar 1992, In: Tropical Medicine and Parasitology. 43, 1, p. 68-9 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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