Novo Nordisk Foundation Center for Basic Metabolic Research

  1. Published

    Variants in EFCAB7 underlie nonsyndromic postaxial polydactyly

    Bilal, M., Khan, H., Khan, M. J., Haack, T. B., Buchert, R., Liaqat, K., Ullah, K., Ahmed, S., Bharadwaj, T., Acharya, A., Peralta, S., Najumuddin, Ali, H., Hasni, M. S., Schrauwen, I., Ullah, A., Ahmad, W. & Leal, S. M., 2023, In: European Journal of Human Genetics. 31, 11, p. 1270-1274

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Variants at the Interleukin 1 Gene Locus and Pericarditis

    Thorolfsdottir, R. B., Jonsdottir, A. B., Sveinbjornsson, G., Aegisdottir, H. M., Oddsson, A., Stefansson, O. A., Halldorsson, G. H., Saevarsdottir, S., Thorleifsson, G., Stefansdottir, L., Pedersen, O. B., Sørensen, E., Ghouse, J., Raja, A. A., Zheng, C., Silajdzija, E., Rand, S. A., Erikstrup, C., Ullum, H., Mikkelsen, C. & 26 others, Banasik, Karina, Brunak, Søren, Ivarsdottir, E. V., Sigurdsson, A., Beyter, D., Sturluson, A., Einarsson, H., Tragante, V., Helgason, H., Lund, S. H., Halldorsson, B. V., Sigurpalsdottir, B. D., Olafsson, I., Arnar, D. O., Thorgeirsson, G., Knowlton, K. U., Nadauld, L. D., Gretarsdottir, S., Helgadottir, A., Ostrowski, Sisse Rye, Gudbjartssson, D. F., Jonsdottir, I., Bundgård, Henning, Holm, H., Sulem, P. & Stefansson, K., 2024, In: JAMA Cardiology. 9, 2, p. 165-172 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Variants at DGKB/TMEM195, ADRA2A, GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish people

    Boesgaard, T. W., Grarup, Niels, Jørgensen, T., Borch-Johnsen, K., Hansen, Torben, Pedersen, Oluf Borbye & Meta-Analysis of Glucose and Insulin-Related Trait Consortium (MAGIC), M. O. G. A. I. T. C. (., 1 Aug 2010, In: Diabetologia. 53, 8, p. 1647-55 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Variant near ADAMTS9 known to associate with type 2 diabetes is related to insulin resistance in offspring of type 2 diabetes patients--EUGENE2 study

    Boesgaard, T. W., Gjesing, A. P., Grarup, N., Rutanen, J., Jansson, P., Hribal, M. L., Sesti, G., Fritsche, A., Stefan, N., Staiger, H., Häring, H., Smith, U., Laakso, M., Pedersen, Oluf Borbye, Hansen, T. & EUGENE2 Consortium, E. C., 2009, In: PLoS ONE. 4, 9, p. e7236

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Variant ASGR1 Associated with a Reduced Risk of Coronary Artery Disease

    Nioi, P., Sigurdsson, A., Thorleifsson, G., Helgason, H., Agustsdottir, A. B., Norddahl, G. L., Helgadottir, A., Magnusdottir, A., Jonasdottir, A., Gretarsdottir, S., Jonsdottir, I., Steinthorsdottir, V., Rafnar, T., Swinkels, D. W., Galesloot, T. E., Grarup, N., Jørgensen, T., Vestergaard, H., Hansen, T., Lauritzen, T. & 34 others, Linneberg, Allan René, Friedrich, N., Krarup, N. T., Fenger, M., Abildgaard, U., Hansen, Peter Riis, Galløe, A. M., Braund, P. S., Nelson, C. P., Hall, A. S., Williams, M. J. A., van Rij, A. M., Jones, G. T., Patel, R. S., Levey, A. I., Hayek, S., Shah, S. H., Reilly, M., Eyjolfsson, G. I., Sigurdardottir, O., Olafsson, I., Kiemeney, L. A., Quyyumi, A. A., Rader, D. J., Kraus, W. E., Samani, N. J., Pedersen, Oluf Borbye, Thorgeirsson, G., Masson, G., Holm, H., Gudbjartsson, D., Sulem, P., Thorsteinsdottir, U. & Stefansson, K., 2 Jun 2016, In: New England Journal of Medicine. 374, 22, p. 2131-2141 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Variance of the SGK1 gene is associated with insulin secretion in different European populations: results from the TUEF, EUGENE2, and METSIM studies.

    Friedrich, B., Weyrich, P., Stancáková, A., Wang, J., Kuusisto, J., Laakso, M., Sesti, G., Succurro, E., Smith, U., Hansen, Torben, Pedersen, Oluf Borbye, Machicao, F., Schäfer, S., Lang, F., Risler, T., Ullrich, S., Stefan, N., Fritsche, A. & Häring, H., 2008, In: PLoS ONE. 3, 11, p. e3506

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Variable reliability of surrogate measures of insulin sensitivity after Roux-en-Y gastric bypass

    Bojsen-Møller, K. N., Dirksen, C., Svane, M. S., Jørgensen, N. B., Holst, Jens Juul, Richter, Erik A. & Madsbad, Sten, 2017, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 312, 5, p. R797-R805 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Variability in response to albuminuria-lowering drugs: true or random?

    Petrykiv, S. I., de Zeeuw, D., Persson, F., Rossing, Peter, Gansevoort, R. T., Laverman, G. D. & Heerspink, H. J. L., Jun 2017, In: British Journal of Clinical Pharmacology. 83, 6, p. 1197-1204 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Validation of a multimarker model for assessing risk of type 2 diabetes from a five-year prospective study of 6784 Danish people (Inter99)

    Urdea, M., Kolberg, J., Wilber, J., Gerwien, R., Moler, E., Rowe, M., Jorgensen, P., Hansen, T., Pedersen, Oluf Borbye, Jørgensen, T. & Borch-Johnsen, K., 2009, In: Journal of Diabetes Science and Technology. 3, 4, p. 748-55 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Validation of a multi-marker model for the prediction of incident type 2 diabetes mellitus: Combined results of the Inter99 and Botnia studies

    Lyssenko, V., Jørgensen, T., Gerwien, R. W., Hansen, Torben, Rowe, M. W., McKenna, M. P., Kolberg, J., Pedersen, Oluf Borbye, Borch-Johnsen, K. & Groop, L., Jan 2012, In: Diabetes and Vascular Disease Research. 9, 1

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Vagal control of the release of somatostatin, vasoactive intestinal polypeptide, gastrin-releasing peptide, and HCl from porcine non-antral stomach

    Holst, Jens Juul, Skak-Nielsen, T., Ørskov, Cathrine & Seier-Poulsen, S., Aug 1992, In: Scandinavian Journal of Gastroenterology. 27, 8, p. 677-85 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Vagal control of the release of somatostatin, vasoactive intestinal polypeptide, gastrin releasing peptide and HC1 from porcine non-antral stomach

    Holst, Jens Juul, Skak-Nielsen, T., Ørskov, C. & Poulsen, S. S., 1992, In: Scandinavian Journal of Gastroenterology. 27, p. 677-685

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Vagal afferent cholecystokinin receptor activation is required for glucagon-like peptide-1–induced satiation

    Vana, V., Lærke, M. K., Rehfeld, Jens Frederik, Arnold, M., Dmytriyeva, O., Langhans, W., Schwartz, Thue W. & Hansen, Harald S., 2022, In: Diabetes, Obesity and Metabolism. 24, 2, p. 268-280

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Vagal Blocking for Obesity Control: a Possible Mechanism-Of-Action

    Johannessen, H., Revesz, D., Kodama, Y., Cassie, N., Skibicka, K. P., Barrett, P., Dickson, S., Holst, Jens Juul, Rehfeld, Jens Frederik, van der Plasse, G., Adan, R., Kulseng, B., Ben-Menachem, E., Zhao, C. & Chen, D., Jan 2017, In: Obesity Surgery. 27, 1, p. 177-185 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Vaccine Targeting of Subdominant CD8+ T Cell Epitopes Increases the Breadth of the T Cell Response upon Viral Challenge, but May Impair Immediate Virus Control

    Steffensen, Maria Abildgaard, Pedersen, L. H., Jahn, Marie Louise, Nielsen, K. N., Christensen, Jan Pravsgaard & Thomsen, Allan Randrup, 15 Mar 2016, In: Journal of Immunology. 196, 6, p. 2666-2676 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Vaccinations against smallpox and tuberculosis are associated with better long-term survival: a Danish case-cohort study 1971-2010

    Rieckmann, Andreas, Villumsen, M., Sørup, S., Haugaard, L. K., Ravn, H., Roth, A., Baker, J. L., Benn, C. S. & Aaby, P., 5 Jul 2016, In: International Journal of Epidemiology. 2016, p. 1-11 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    VPS39-deficiency observed in type 2 diabetes impairs muscle stem cell differentiation via altered autophagy and epigenetics

    Davegårdh, C., Säll, J., Benrick, A., Broholm, C., Volkov, P., Perfilyev, A., Henriksen, T. I., Wu, Y., Hjort, L., Brøns, C., Hansson, O., Pedersen, M., Würthner, J. U., Pfeffer, K., Nilsson, E., Vaag, Allan, Stener-Victorin, E., Pircs, K., Schéele, Camilla Charlotte Nielsen & Ling, C., 2021, In: Nature Communications. 12, 1, 20 p., 2431.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Utilizing the gut microbiome in decompensated cirrhosis and acute-on-chronic liver failure

    Trebicka, J., Bork, P., Krag, A. & Arumugam, Mani, 2021, In: Nature Reviews Gastroenterology & Hepatology. 18, p. 167-180 14 p.

    Research output: Contribution to journalReviewResearchpeer-review

  19. Published

    Utilizing social media to study information-seeking and ethical issues in gene therapy

    Robillard, J. M., Whiteley, Louise, Johnson, T. W., Lim, J., Wasserman, W. W. & Illes, J., 2013, In: Journal of Medical Internet Research. 15, 3, p. e44

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Utility of Plasma Concentration of Trimethylamine N-Oxide in Predicting Cardiovascular and Renal Complications in Individuals With Type 1 Diabetes

    Winther, S. A., Øllgaard, J. C., Tofte, N., Tarnow, L., Wang, Z., Ahluwalia, T. S., Jorsal, A., Theilade, S., Parving, H., Hansen, T. W., Hazen, S. L., Pedersen, Oluf Borbye & Rossing, Peter, 2019, In: Diabetes Care. 42, 8, p. 1512-1520

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Using importance sampling to improve simulation in linkage analysis

    Ängquist, Lars & Hössjer, O., 1 Jan 2004, In: Statistical Applications in Genetics and Molecular Biology. 3, 1, 5.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Using a Reporter Mouse to Map Known and Novel Sites of GLP-1 Receptor Expression in Peripheral Tissues of Male Mice

    Andersen, Daniel Bjørklund, Grunddal, Kaare Villum, Pedersen, Jens, Kuhre, Rune Ehrenreich, Lund, M. L., Holst, Jens Juul & Ørskov, Cathrine, 2021, In: Endocrinology. 162, 3, bqaa246.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Usefulness of Heat Map Explanations for Deep-Learning-Based Electrocardiogram Analysis

    Storås, A. M., Andersen, O. E., Lockhart, S., Thielemann, Roman, Gnesin, Filip Jurijevitj, Thambawita, Vajira Lasantha Bandara, Hicks, S. A., Kanters, Jørgen K., Strümke, I., Halvorsen, P. & Riegler, M. A., 2023, In: Diagnostics. 13, 14, 11 p., 2345.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Use of inhaled corticosteroids and the risk of developing type 2 diabetes in patients with chronic obstructive pulmonary disease

    Saeed, M. I., Eklof, J., Achir, I., Sivapalan, P., Meteran, Howraman, Lokke, A., Biering-Sørensen, Tor, Knop, Filip Krag & Jensen , Jens-Ulrik Stæhr , 2020, In: Diabetes, Obesity and Metabolism. 22, 8, p. 1348-1356 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Use of anesthesia dramatically alters the oral glucose tolerance and insulin secretion in C57Bl/6 mice

    Windeløv, Johanne Agerlin, Pedersen, Jens & Holst, Jens Juul, Jun 2016, In: Physiological Reports. 4, 11, 6 p., e12824.

    Research output: Contribution to journalJournal articleResearchpeer-review

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