- Published
Transgenic rescue of adipocyte glucose-dependent insulinotropic polypeptide receptor expression restores high fat diet-induced body weight gain
Ugleholdt, Randi Kjærsgaard, Pedersen, Jens, Bassi, Maria Rosaria, Füchtbauer, E., Jørgensen, S. M., Kissow, Hannelouise, Nytofte, N., Poulsen, Steen Seier, Rosenkilde, Mette, Seino, Y., Thams, P., Holst, Peter Johannes & Holst, Jens Juul, Dec 2011, In: The Journal of Biological Chemistry. 286, 52, p. 44632-44645 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Transforming growth factor β1 impairs the transcriptomic response to contraction in myotubes from women with polycystic ovary syndrome
McIlvenna, L. C., Altıntaş, Ali, Patten, R. K., McAinch, A. J., Rodgers, R. J., Stepto, N. K., Barrès, Romain & Moreno-Asso, A., 2022, In: The Journal of Physiology. 600, 14, p. 3313-3330Research output: Contribution to journal › Journal article › Research › peer-review
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Transfer of liraglutide from blood to cerebrospinal fluid is minimal in patients with type 2 diabetes
Christensen, M., wbf943, wbf943, Hartmann, Bolette, Grevstad, U., Rosenkilde, Mette, Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, Nov 2015, In: International journal of obesity (2005). 39, 11, p. 1651-1654 4 p.Research output: Contribution to journal › Letter › Research › peer-review
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Transcriptomics analysis of differentially expressed genes in subcutaneous and perirenal adipose tissue of sheep as affected by their pre- and early postnatal malnutrition histories
Ahmad, S., Drag, Markus Hodal, Salleh, S. M., Cai, Z. & Nielsen, M. O., 2021, In: BMC Genomics. 22, 1, 21 p., 338.Research output: Contribution to journal › Journal article › Research › peer-review
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Transcriptomic profiling of skeletal muscle adaptations to exercise and inactivity
Pillon, N. J., Gabriel, B. M., Dollet, L., Smith, J. A. B., Puig, L. S., Botella, J., Bishop, D. J., Krook, A. & Zierath, Juleen R, 2020, In: Nature Communications. 11, 1, 15 p., 470.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcriptomic profiling of pancreatic alpha, beta and delta cell populations identifies delta cells as a principal target for ghrelin in mouse islets
Adriaenssens, A. E., Svendsen, B., Lam, B. Y. H., Yeo, G. S. H., Holst, Jens Juul, Reimann, F. & Gribble, F. M., Oct 2016, In: Diabetologia. 59, 10, p. 2156-2165 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Transcriptomic and epigenomics atlas of myotubes reveals insight into the circadian control of metabolism and development
Altıntaş, Ali, Laker, R. C., Garde, C., Barrès, Romain & Zierath, Juleen R, 2020, In: Epigenomics. 12, 8, p. 701-713Research output: Contribution to journal › Journal article › Research › peer-review
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Transcriptomic and epigenetic responses to short-term nutrient-exercise stress in humans
Laker, R. C., Garde, C., Camera, D. M., Smiles, W. J., Zierath, Juleen R, Hawley, J. A. & Barrès, Romain, 9 Nov 2017, In: Scientific Reports. 7, 1, 12 p., 15134.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcriptomic analysis links diverse hypothalamic cell types to fibroblast growth factor 1-induced sustained diabetes remission
Bentsen, M. A., Rausch, D. M., Mirzadeh, Z., Muta, K., Scarlett, J. M., Brown, J. M., Herranz-Pérez, V., Baquero, A. F., Thompson, J., Alonge, K. M., Faber, C. L., Kaiyala, K. J., Bennett, C., Pyke, C., Ratner, C., Egerod, K. L., Holst, B., Meek, T. H., Kutlu, B., Zhang, Y. & 9 others, , 2020, In: Nature Communications. 11, 1, 4458.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcriptome complexity in a genome-reduced bacterium.
Güell, M., van Noort, V., Yus, E., Chen, W., Leigh-Bell, J., Michalodimitrakis, K., Yamada, T., Arumugam, Mani, Doerks, T., Kühner, S., Rode, M., Suyama, M., Schmidt, S., Gavin, A., Bork, P. & Serrano, L., Nov 2009, In: Science. 326, 5957, p. 1268-1271 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcriptome and network changes in climbers at extreme altitudes
Chen, F., Zhang, W., Liang, Y., Huang, J., Li, K., Green, C. D., Liu, J., Zhang, G., Zhou, B., Yi, X., Wang, W., Liu, H., Xu, X., Shen, F., Qu, N., Wang, Y., Gao, G., San, A., JiangBai, L., Sang, H. & 6 others, , 2012, In: P L o S One. 7, 2, p. e31645-e31645Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcriptome analysis uncover differential regulation in cell cycle, immunity, and metabolism in Anopheles albimanus during immune priming with Plasmodium berghei
Maya-Maldonado, K., Cime-Castillo, J., Maya, Otoniel, Argotte-Ramos, R., Rodríguez, M. C. & Lanz-Mendoza, H., 2021, In: Developmental and Comparative Immunology. 120, 104046.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcriptional profiling of extracellular amino acid sensing in Saccharomyces cerevisiae and the role of Stp 1 p and Stp2p
Eckert-Boulet, N., Nielsen, P. S., Friis, Carsten, Moreira dos Santos, M., Nielsen, J., Kielland-Brandt, M. C. & Regenberg, Birgitte, 1 Jun 2004, In: Yeast. 21, 8, p. 635-648 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcriptional interactions suggest niche segregation among microorganisms in the human gut
Plichta, D. R., Juncker, A. S., Bertalan, M., Rettedal, E., Gautier, L., Varela, E., Manichanh, C., Fouqueray, C., Levenez, F., Nielsen, T., Doré, J., Machado, A. M. D., de Evgrafov, M. C. R., Hansen, T., Jørgensen, T., Bork, P., Guarner, F., Pedersen, O., Metagenomics of the Human Intestinal Tract (MetaHIT) Consortium, Sommer, M. O. A. & 4 others, , 26 Aug 2016, In: Nature Microbiology. 1, p. 1-6 6 p., 16152.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Transcriptional and translational regulation of cytokine signaling in inflammatory ß-cell dysfunction and apoptosis
Novotny, G. W., Lundh, M., Backe, M. B., Christensen, D. P., Hansen, J. B., Dahllöf, M. S., Pallesen, E. & Mandrup-Poulsen, Thomas, 2012, In: Archives of Biochemistry and Biophysics. 528, 2, p. 171-84Research output: Contribution to journal › Review › Research › peer-review
- Published
Transcriptional and epigenomic profiling identifies YAP signaling as a key regulator of intestinal epithelium maturation
Pikkupeura, Laura Maarit, Bardini Bressan, Raul, Guiu, J., Chen, Y., Maimets, Martti, Mayer, Daniela, Schweiger, P. J., Hansen, Stine Lind, Maciag, Grzegorz Jerzy, Larsen, Hjalte List, Lõhmussaar, Kadi, Pedersen, M. T., Teves, Joji Marie Yap, Lange, Jette Bornholdt, Benes, V., Sandelin, Albin Gustav & Jensen, Kim Bak, 2023, In: Science Advances. 9, 28, 16 p., eadf9460.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcriptional and Functional Characterization of the G Protein-Coupled Receptor Repertoire of Gastric Somatostatin Cells
Egerod, Kristoffer Lihme, Engelstoft, M. S., Lund, M. L., Grunddal, Kaare Villum, Zhao, M., Barir-Jensen, D., Nygaard, E. B., Petersen, N., Holst, Jens Juul & Schwartz, Thue W., Nov 2015, In: Endocrinology. 156, 11, p. 3909-23 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Transcription factor EB and TFE3: new metabolic coordinators mediating adaptive responses to exercise in skeletal muscle?
Markby, G. R. & Sakamoto, Kei, 2020, In: American Journal of Physiology: Endocrinology and Metabolism. 319, 4, p. E763-E768 6 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Trans-ethnic gut microbiota signatures of type 2 diabetes in Denmark and India
Alvarez-Silva, C., Kashani, A., Hansen, T. H., Pinna, N. K., Anjana, R. M., Dutta, A., Saxena, S., Støy, J., Kampmann, U., Nielsen, T., Jørgensen, T., Gnanaprakash, V., Gnanavadivel, R., Sukumaran, A., Rani, C. S. S., Færch, K., Radha, V., Balasubramanyam, M., Nair, G. B., Das, B. & 6 others, , 2021, In: Genome Medicine. 13, 37.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Trans-ethnic gut microbial signatures of prediabetic subjects from India and Denmark
Pinna, N. K., Anjana, R. M., Saxena, S., Dutta, A., Gnanaprakash, V., Rameshkumar, G., Aswath, S., Raghavan, S., Rani, C. S. S., Radha, V., Balasubramanyam, M., Pant, A., Nielsen, T., Jørgensen, T., Færch, K., Kashani, A., Silva, M. C. A., Vestergaard, H., Hansen, T. H., Hansen, T. & 6 others, , 2021, In: Genome Medicine. 13, 20 p., 36.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations
Chen, M-H., Raffield, L. M., Mousas, A., Sakaue, S., Huffman, J. E., Moscati, A., Trivedi, B., Jiang, T., Akbari, P., Vuckovic, D., Bao, E. L., Zhong, X., Manansala, R., Laplante, V., Chen, M., Lo, K. S., Qian, H., Lareau, C. A., Beaudoin, M., Hunt, K. A. & 31 others, , 2020, In: Cell. 182, 5, p. 1198-+ 30 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension
Surendran, P., Drenos, F., Young, R., Warren, H., Cook, J. P., Manning, A. K., Grarup, N., Sim, X., Barnes, D. R., Witkowska, K., Staley, J. R., Tragante, V., Tukiainen, T., Yaghootkar, H., Masca, N., Freitag, D. F., Ferreira, T., Giannakopoulou, O., Tinker, A., Harakalova, M. & 32 others, , 12 Sep 2016, In: Nature Genetics. 48, 10, p. 1151-1161 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation
Kato, N., Loh, M., Takeuchi, F., Verweij, N., Wang, X., Zhang, W., Kelly, T. N., Saleheen, D., Lehne, B., Mateo Leach, I., Drong, A. W., Abbott, J., Wahl, S., Tan, S-T., Scott, W. R., Campanella, G., Chadeau-Hyam, M., Afzal, U., Ahluwalia, T. V. S., Bonder, M. J. & 31 others, , 2015, In: Nature Genetics. 47, 11, p. 1282-93 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Trans-ancestral genome-wide association study of longitudinal pubertal height growth and shared heritability with adult health outcomes
Bradfield, J. P., Kember, R. L., Ulrich, A., Balkiyarova, Z., Alyass, A., Aris, I. M., Bell, J. A., Broadaway, K. A., Chen, Z., Chai, J-F., Davies, N. M., Fernandez-Orth, D., Bustamante, M., Fore, R., Ganguli, A., Heiskala, A., Hottenga, J-J., Íñiguez, C., Kobes, S., Leinonen, J. & 33 others, , 2024, In: Genome Biology. 25, 19 p., 22.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Train like an athlete: applying exercise interventions to manage type 2 diabetes
Savikj, M. & Zierath, Juleen R, 2020, In: Diabetologia. 63, 8, p. 1491-1499Research output: Contribution to journal › Review › Research › peer-review
- Published
Tracking of leptin, soluble leptin receptor, and the free leptin index during weight loss and regain in children
Holm, J., Gamborg, M., Ward, L. C., Gammeltoft, S., Kaas-Ibsen, K., Heitmann, B. L. & Sørensen, Thorkild I.A., 2011, In: Obesity Facts. 4, 6, p. 461-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tracking of body mass index from 7 to 69 years of age
Aarestrup, J., Bjerregaard, L. G., Gamborg, Michael Orland, Ängquist, Lars, Tjønneland, Anne, Overvad, K., Linneberg, Allan René, Osler, Merete, Mortensen, Erik Lykke, Gyntelberg, F., Lund, Rikke, Sørensen, Thorkild I.A. & Baker, J. L., Sep 2016, In: International Journal of Obesity. 40, 9, p. 1376-1383 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tracing the origin of adult intestinal stem cells
Guiu, J., Hannezo, E., Yui, S., Demharter, S., Ulyanchenko, Svetlana, Maimets, Martti, Jørgensen, A., Perlman, S., Lundvall, L., Mamsen, L. S., Larsen, A., Olesen, R. H., Andersen, C. Y., Thuesen, L. L., Hare, Kristine Juul, Pers, Tune H, Khodosevich, Konstantin, Simons, B. D. & Jensen, Kim Bak, 2019, In: Nature. 570, 7759, p. 107-111Research output: Contribution to journal › Letter › Research › peer-review
- Published
Tracing the biological roots of obesity resistance in humans
Lund, Jens, 2023, In: Nature Reviews Endocrinology. 19, p. 500 1 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Towards leanness by 'feeding' a novel thermogenic pathway?
Lund, Jens & Gillum, M. P., Aug 2016, In: Trends in Endocrinology and Metabolism. 27, 8, p. 529-530 2 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Total and Trimester-Specific Gestational Weight Gain and Offspring Birth and Early Childhood Weight: A Prospective Cohort Study on Monozygotic Twin Mothers and Their Offspring
Scheers Andersson, E., Silventoinen, K., Tynelius, P., Nohr, E. A., Sørensen, Thorkild I.A. & Rasmussen, F., Aug 2016, In: Twin Research and Human Genetics. 19, 4, p. 367-76 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Too narrow and too broad: Differentiating late-onset dementiafrom its historical entanglement with Alzheimer’s disease
Moseholm, Kristine Frøsig, Tybjerg, Karin, Jensen, Majken Karoline & Westendorp, Rudi GJ, Mar 2021, In: Aging Brain. 1, 100010.Research output: Contribution to journal › Journal article › Research
- Published
Tolerable Duration of Warm Ischaemia After Circulatory Death Is Safe For At Least One Hour in Porcine Lungs: Functional Assessment with Ex Vivo Lung Perfusion
Hebsgaard, M. M. B., Kissow, Hannelouise, Lilleør, N. B., Lorenzen, U. S., Chemtob, R. A., Møller-Sørensen, H., Olsen, P. S. & Møller, Christian H., 2022, In: Heart Surgery Forum. 25, 1, p. E48-E52 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
To see and then to act, that is the challenge
Sørensen, Thorkild I.A., Sep 2017, In: European Journal of Epidemiology. 32, 9, p. 737-739 3 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Tissue levels and post-prandial secretion of the intestinal growth factor, glucagon-like peptide-2, in controls and inflammatory bowel disease: comparison with peptide YY
Schmidt, P. T., Ljung, T., Hartmann, Bolette, Hare, K. J., Holst, Jens Juul & Hellström, P. M., Feb 2005, In: European journal of gastroenterology & hepatology. 17, 2, p. 207-12 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tissue and plasma concentrations of amidated and glycine-extended glucagon-like peptide-1 in humans
Ørskov, Cathrine, Rabenhøj, L., Wettergren, A., Kofod, H. & Holst, Jens Juul, 1994, In: Diabetes. 43, p. 535-539Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tissue and plasma concentrations of amidated and glycine-extended glucagon-like peptide I in humans
Ørskov, Cathrine, Rabenhøj, L., Wettergren, A., Kofod, H. & Holst, Jens Juul, Apr 1994, In: Diabetes. 43, 4, p. 535-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tirzepatide is an imbalanced and biased dual GIP and GLP-1 receptor agonist
Willard, F. S., Douros, J. D., Gabe, M., Showalter, A. D., Wainscott, D. B., Suter, T. M., Capozzi, M. E., van der Velden, W. J. C., Stutsman, C., Cardona, G. R., Urva, S., Emmerson, P. J., Holst, Jens Juul, D'Alessio, D. A., Coghlan, M. P., Rosenkilde, Mette, Campbell, J. E. & Sloop, K. W., 2020, In: JCI insight. 5, 17, 16 p., 140532.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Timing of motor milestones achievement and development of overweight in childhood: a study within the Danish National Birth Cohort
Morgen, C. S., Nybo Andersen, Anne-Marie, Due, P., Neelon, S. B., Gamborg, Michael Orland & Sørensen, Thorkild I.A., Aug 2014, In: Pediatric Obesity. 9, 4, p. 239-48 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Timing of Ca2+ response in pancreatic beta-cells is related to mitochondrial mass
Gustavsson, N., Abedi, G., Larsson-Nyrén, G. & Lindström, P., 24 Feb 2006, In: Molecular Cell Biology Research Communications. 340, 4, p. 1119-24 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Timeless spaces: Field experiments in the physiological study of circadian rhythms, 1938–1963
Hussey, Kristin D., 2023, In: History and Philosophy of the Life Sciences. 45, 25 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Time-restricted feeding alters lipid and amino acid metabolite rhythmicity without perturbing clock gene expression: [Author Correction]
Lundell, L. S., Parr, E. B., Devlin, B. L., Ingerslev, L. R., Altıntaş, Ali, Sato, S., Sassone-Corsi, P., Barrès, Romain, Zierath, Juleen R & Hawley, J. A., 2020, In: Nature Communications. 11, 1, 11 p., 4643.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Time-resolved hypothalamic open flow micro-perfusion reveals normal leptin transport across the blood–brain barrier in leptin resistant mice
Kleinert, Maximilian, Kotzbeck, P., Altendorfer-Kroath, T., Birngruber, T., Tschöp, M. H. & Clemmensen, Christoffer, 2018, In: Molecular Metabolism. 13, p. 77-82 6 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Time-Resolved quantitative phosphoproteomics: New insights into angiotensin-(1-7) signaling networks in human endothelial cells
Verano-Braga, T., Schwämmle, V., Sylvester, M., Passos-Silva, D. G., Peluso, A. A. B., Etelvino, G. M., Santos, R. A. S. & Roepstorff, P., 2012, In: Journal of Proteome Research.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Time trends in epigenetic signatures and population health risks
Sørensen, Thorkild I.A. & Barrès, Romain, 2021, Twin and Family Studies of Epigenetics. Li, S. & Hopper, J. L. (eds.). Elsevier Ltd. Academic Press, p. 285-298 (Translational Epigenetics, Vol. 27).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Time of day determines postexercise metabolism in mouse adipose tissue
Pendergrast, L. A., Lundell, L. S., Ehrlich, Amy M, Ashcroft, Stephen Paul, Schönke, M., Basse, A. L., Krook, A., Treebak, Jonas Thue, Dollet, L. & Zierath, Juleen R, 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 8, e2218510120.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Time of Exercise Specifies the Impact on Muscle Metabolic Pathways and Systemic Energy Homeostasis
Sato, S., Basse, A. L., Schönke, M., Chen, S., Samad, M., Altıntaş, Ali, Laker, R. C., Kellezi, Emilie Dalbram, Barrès, Romain, Baldi, P., Treebak, Jonas Thue, Zierath, Juleen R & Sassone-Corsi, P., 2019, In: Cell Metabolism. 30, 1, p. 92-110.e4 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Thyrotropin-releasing hormone induces Ca2+ increase in a subset of vagal nodose ganglion neurons
Mamedova, Esmira, Dmytriyeva, O. & Rekling, Jens Christian, 2022, In: Neuropeptides. 94, 9 p., 102261.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Thyroid hormone receptor α in skeletal muscle is essential for T3-mediated increase in energy expenditure
Nicolaisen, T. S., Klein, A. B., Dmytriyeva, O., Lund, Jens, Ingerslev, L. R., Fritzen, Andreas Mæchel, Carl, Christian Strini, Lundsgaard, Anne-Marie, Frost, M., Ma, Tao, Schjerling, P., Gerhart-Hines, Zach, Flamant, F., Gauthier, K., Larsen, Steen, Richter, Erik A., Kiens, Bente & Clemmensen, Christoffer, 2020, In: F A S E B Journal. 34, 11, p. 15480-15491 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Three-phase bone scintigraphy for diagnosis of Charcot neuropathic osteoarthropathy in the diabetic foot – does quantitative data improve diagnostic value?
Fosbol, M., Reving, S., Petersen, E. H., Rossing, Peter, Lajer, M. & Zerahn, B., Jan 2017, In: Clinical Physiology and Functional Imaging. 37, 1, p. 30-36Research output: Contribution to journal › Journal article › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity
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