Novo Nordisk Foundation Center for Basic Metabolic Research

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  1. Published

    Unanswered questions about the causes of obesity

    Speakman, J. R., Sørensen, Thorkild I.A., Hall, K. D. & Allison, D. B., 2023, In: Science. 381, 6661, p. 944-946 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Tænkningens udsving - et essay om at tænke i en pandemisk situation

    Grünfeld, Martin, 2020, In: Sundhed og Samfund. 33, p. 167-172 6 p.

    Research output: Contribution to journal › Journal article › Research

  3. Published

    Type 2 diabetes susceptibility gene variants predispose to adult-onset autoimmune diabetes

    Lepola, Mette Andersen, Sterner, M., Forsén, T., Käräjämäki, A., Rolandsson, O., Forsblom, C., Groop, P. H., Lahti, K., Nilsson, P. M., Groop, L. & Tuomi, T., 1 Jan 2014, In: Diabetologia. 57, 9, p. 1859-1868 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Type 2 diabetes risk alleles near ADCY5, CDKAL1 and HHEX-IDE are associated with reduced birthweight

    Andersson, E. A., Pilgaard, K., Pisinger, C., Harder, M. N., Grarup, Niels, Faerch, K., Poulsen, P., Witte, D. R., Jørgensen, T., Vaag, Allan, Hansen, Torben & Pedersen, Oluf Borbye, 1 Sep 2010, In: Diabetologia. 53, 9, p. 1908-16 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Type 2 diabetes risk allele near CENTD2 is associated with decreased glucose-stimulated insulin release

    Nielsen, T., Sparsø, T., Grarup, Niels, Jørgensen, T., Pisinger, C. H., Witte, D. R., Hansen, T., Pedersen, Oluf Borbye & Diabetes Genetics Replication and Meta-analysis (DIAGRAM) Consortium, D. G. R. A. M. (. C., 1 May 2011, In: Diabetologica. 54, 5, p. 1052-6 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Type 2 diabetes mellitus

    DeFronzo, R. A., Ferrannini, E., Groop, L., Henry, R. R., Herman, W. H., Holst, Jens Juul, Hu, F. B., Kahn, C. R., Raz, I., Shulmann, G. I., Simonson, D. C., Testa, M. A. & Weiss, R., 2015, In: Nature Reviews. Disease Primers. 1, 22 p., 15019.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Type 2 diabetes is associated with increased circulating levels of 3-hydroxydecanoate activating GPR84 and neutrophil migration

    Mikkelsen, R. B., Arora, Tulika, Trošt, K., Dmytriyeva, O., Jensen, Sune K. , Meijnikman, A. S., Olofsson, L. E., Lappa, D., Aydin, Ö., Nielsen, J., Gerdes, V., Moritz, Thomas, van de Laar, A., de Brauw, M., Nieuwdorp, M., Hjorth, Siv Annegrethe, Schwartz, Thue W. & Bäckhed, F., 2022, In: iScience. 25, 12, 29 p., 105683.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Type 2 diabetes influences bacterial tissue compartmentalisation in human obesity

    Anhê, F. F., Jensen, Benjamin Anderschou Holbech, Varin, T. V., Servant, F., Van Blerk, S., Richard, D., Marceau, S., Surette, M., Biertho, L., Lelouvier, B., Schertzer, J. D., Tchernof, A. & Marette, A., 2020, In: Nature Metabolism. 2, 3, p. 233-242 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Type 2 diabetes classification: a data-driven cluster study of the Danish Centre for Strategic Research in Type 2 Diabetes (DD2) cohort

    Christensen, D. H., Nicolaisen, S. K., Ahlqvist, E., Stidsen, J. V., Nielsen, J. S., Hojlund, K., Olsen, M. H., García-Calzón, S., Ling, C., Rungby, Jørgen, Brandslund, I., Vestergaard, P., Jessen, N., Hansen, Torben, Brøns, C., Beck-Nielsen, H., Sørensen, H. T., Thomsen, R. W. & Vaag, Allan, 2022, In: B M J Open Diabetes Research & Care. 10, 2, 12 p., e002731.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Type 2 diabetes candidate genes, including PAX5, cause impaired insulin secretion in human pancreatic islets

    Bacos, K., Perfilyev, A., Karagiannopoulos, A., Cowan, E., Ofori, J. K., Bertonnier-Brouty, L., Rönn, T., Lindqvist, A., Luan, C., Ruhrmann, S., Ngara, M., Nilsson, Å., Gheibi, S., Lyons, C. L., Lagerstedt, J. O., Barghouth, M., Esguerra, J. L. S., Volkov, P., Fex, M., Mulder, H. & 7 others, Wierup, N., Krus, U., Artner, I., Eliasson, L., Prasad, R. B., Cataldo Bascunan, Luis Rodrigo & Ling, C., 2023, In: Journal of Clinical Investigation. 133, 4, 17 p., e163612.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Type 2 diabetes and obesity induce similar transcriptional reprogramming in human myocytes

    Väremo, L., Henriksen, T. I., Schéele, Camilla Charlotte Nielsen, Broholm, C., Pedersen, M., Uhlén, M., Pedersen, Bente Klarlund & Nielsen, J., 25 May 2017, In: Genome Medicine. 9, 12 p., 47.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Type 2 Diabetes risk alleles in Peptidyl-glycine Alpha-amidating Monooxygenase influence GLP-1 levels and response to GLP-1 Receptor Agonists

    Umapathysivam, M. M., Araldi, E., Hastoy, B., Dawed, A. Y., Vatandaslar, H., Sengupta, S., Kaufmann, A., Thomsen, S., Hartmann, B., Jonsson, A. E., Kabakci, H., Thaman, S., Grarup, N., Have, C. T., Færch, K., Gjesing, A. P., Nawaz, S., Cheeseman, J., Neville, M. J., Pedersen, O. & 12 others, Walker, M., Jennison, C., Hattersley, A. T., Hansen, Torben, Karpe, F., Holst, Jens Juul, Jones, A. G., Ristow, M., McCarthy, M. I., Pearson, E. R., Stoffel, M. & Gloyn, A. L., 2023, medRxiv, 35 p.

    Research output: Working paper › Preprint › Research

  13. Published

    Type 2 Diabetes Risk Alleles Near BCAR1 and in ANK1 Associate With Decreased ß-Cell Function Whereas Risk Alleles Near ANKRD55 and GRB14 Associate With Decreased Insulin Sensitivity in the Danish Inter99 Cohort

    Harder, M. N., Ribel-Madsen, R., Justesen, Johanne Marie, Sparsø, T., Galijatovic, E. A. A., Grarup, Niels, Jørgensen, T., Linneberg, Allan René, Hansen, Torben & Pedersen, Oluf Borbye, 1 Apr 2013, In: Journal of Clinical Endocrinology and Metabolism. 98, 4, p. 801-806

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Two-step derivatization for determination of sugar phosphates in plants by combined reversed phase chromatography/tandem mass spectrometry

    Rende, U., Niittylae, T. & Moritz, Thomas, 2019, In: Plant Methods. 15, 10 p., 127.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Two weeks of metformin treatment induces AMPK dependent enhancement of insulin-stimulated glucose uptake in mouse soleus muscle

    Kristensen, Jonas Møller, Treebak, Jonas Thue, Schjerling, Peter, Goodyear, L., Wojtaszewski, J. F. P. & Wojtaszewski, Jørgen F P, 2014, In: American Journal of Physiology: Endocrinology and Metabolism. 306, 10, p. E1099-E1109 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes

    Gudmundsson, J., Sulem, P., Steinthorsdottir, V., Bergthorsson, J. T., Thorleifsson, G., Manolescu, A., Rafnar, T., Gudbjartsson, D., Agnarsson, B. A., Baker, A., Sigurdsson, A., Benediktsdottir, K. R., Jakobsdottir, M., Blondal, T., Stacey, S. N., Helgason, A., Gunnarsdottir, S., Olafsdottir, A., Kristinsson, K. T., Birgisdottir, B. & 55 others, Ghosh, S., Thorlacius, S., Magnusdottir, D., Stefansdottir, G., Kristjansson, K., Bagger, Y., Wilensky, R. L., Reilly, M. P., Morris, A. D., Kimber, C. H., Adeyemo, A., Chen, Y., Zhou, J., So, W., Tong, P. C. Y., Ng, M. C. Y., Hansen, Torben, Andersen, G., Borch-Johnsen, K., Jorgensen, T., Tres, A., Fuertes, F., Ruiz-Echarri, M., Asin, L., Saez, B., van Boven, E., Klaver, S., Swinkels, D. W., Aben, K. K., Graif, T., Cashy, J., Suarez, B. K., van Vierssen Trip, O., Frigge, M. L., Ober, C., Hofker, M. H., Wijmenga, C., Christiansen, C., Rader, D. J., Palmer, C. N. A., Rotimi, C., Chan, J. C. N., Pedersen, Oluf Borbye, Sigurdsson, G., Benediktsson, R., Jonsson, E., Einarsson, G. V., Mayordomo, J. I., Catalona, W. J., Kiemeney, L. A., Barkardottir, R. B., Gulcher, J. R., Thorsteinsdottir, U., Kong, A. & Stefansson, K., 2007, In: Nature Genetics. 39, 8, p. 977-983 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Two randomized cross-over trials assessing the impact of dietary gluten or wholegrain on the gut microbiome and host metabolic health

    Ibrügger, S., Gøbel, R. J., drb459, drb459, Licht, T. R., Frøkiær, Hanne, Linneberg, Allan René, Hansen, Torben, Gupta, R., Pedersen, Oluf Borbye, Kristensen, M. B. & Lauritzen, Lotte, 2014, In: Journal of Clinical Trials. 4, 4, 9 p., 1000178.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Two Weeks of Metformin Treatment Induces AMPK Dependent Enhancement of Insulin Stimulated Glucose Transport in Mouse Skeletal Muscle

    Kristensen, Jonas Møller, Treebak, Jonas Thue, Goodyear, L. J. & Wojtaszewski, Jørgen F P, 2013, In: Diabetes. 62, Suppl. 1, p. A462 1 p., 1780-P.

    Research output: Contribution to journal › Conference abstract in journal › Research

  19. Published

    Twin's Birth-Order Differences in Height and Body Mass Index From Birth to Old Age: A Pooled Study of 26 Twin Cohorts Participating in the CODATwins Project

    Yokoyama, Y., Jelenkovic, A., Sund, R., Sung, J., Hopper, J. L., Ooki, S., Heikkilä, K., Aaltonen, S., Tarnoki, A. D., Tarnoki, D. L., Willemsen, G., Bartels, M., van Beijsterveldt, T. C. E. M., Saudino, K. J., Cutler, T. L., Nelson, T. L., Whitfield, K. E., Wardle, J., Llewellyn, C. H., Fisher, A. & 48 others, He, M., Ding, X., Bjerregaard-Andersen, M., Beck-Nielsen, H., Sodemann, M., Song, Y., Yang, S., Lee, K., Jeong, H., Knafo-Noam, A., Mankuta, D., Abramson, L., Burt, S. A., Klump, K. L., Ordoñana, J. R., Sánchez-Romera, J. F., Colodro-Conde, L., Harris, J. R., Brandt, I., Nilsen, T. S., Craig, J. M., Saffery, R., Ji, F., Ning, F., Pang, Z., Dubois, L., Boivin, M., Brendgen, M., Dionne, G., Vitaro, F., Martin, N. G., Medland, S. E., Montgomery, G. W., Magnusson, P. K. E., Pedersen, N. L., Aslan, A. K. D., Tynelius, P., Haworth, C. M. A., Plomin, R., Rebato, E., Rose, R. J., Goldberg, J. H., Rasmussen, F., Hur, Y., Sørensen, Thorkild I.A., Boomsma, D. I., Kaprio, J. & Silventoinen, K., 2016, In: Twin Research and Human Genetics. 19, 2, p. 112-24 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Twin study of heritability of eating bread in Danish and Finnish men and women

    Hasselbalch, A. L., Silventoinen, K., Keskitalo, K., Pietiläinen, K. H., Rissanen, A., Heitmann, B. L., Kyvik, K. O., Sørensen, Thorkild I.A. & Kaprio, J., 1 Apr 2010, In: Twin Research and Human Genetics. 13, 2, p. 163-7 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Twelve-Week Treatment With Liraglutide as Add-on to Insulin in Normal-Weight Patients With Poorly Controlled Type 1 Diabetes: A Randomized, Placebo-Controlled, Double-Blind Parallel Study

    Frandsen, C. S., Dejgaard, T. F., Holst, Jens Juul, Andersen, H. U., Thorsteinsson, B. & Madsbad, Sten, Dec 2015, In: Diabetes Care. 38, 12, p. 2250-7 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

    Voight, B. F., Scott, L. J., Steinthorsdottir, V., Morris, A. P., Dina, C., Welch, R. P., Zeggini, E., Huth, C., Aulchenko, Y. S., Thorleifsson, G., McCulloch, L. J., Ferreira, T., Grallert, H., Amin, N., Wu, G., Willer, C. J., Raychaudhuri, S., McCarroll, S. A., Langenberg, C., Hofmann, O. M. & 31 others, Dupuis, J., Qi, L., Segrè, A. V., van Hoek, M., Navarro, P., Ardlie, K., Balkau, B., Benediktsson, R., Bennett, A. J., Blagieva, R., Boerwinkle, E., Bonnycastle, L. L., Bengtsson Boström, K., Bravenboer, B., Bumpstead, S., Burtt, N. P., Charpentier, G., Chines, P. S., Cornelis, M., Couper, D. J., Crawford, G., Doney, A. S. F., Elliott, K. S., Elliott, A. L., Erdos, M. R., Grarup, Niels, Jørgensen, T., Sparsø, T., Hansen, Torben, Pedersen, Oluf Borbye & MAGIC investigators, M. I., 1 Jul 2010, In: Nature Genetics. 42, 7, p. 579-89 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Tunneled peritoneal catheter for refractory ascites in cirrhosis: A randomized case-series

    Kimer, N., Nordheim Riedel, A., Hobolth, L., Mortensen, C., Madsen, Lone Galmstrup, Andersen, M. L., Schiødt, Frank Vinholt, Møller, Søren & Gluud, Lise Lotte, 2020, In: Medicina. 56, 11, 9 p., 565.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Tumor suppressor ASXL1 is essential for the activation of INK4B expression in response to oncogene activity and anti-proliferative signals

    Wu, X., Bekker-Jensen, I. H., Christensen, J., Rasmussen, K. D., Sidoli, S., Qi, Y., Kong, Y., Wang, X., Cui, Y., Xiao, Z., Xu, G., Williams, K., Rappsilber, J., Sønderby, C. K., Winther, Ole, Jensen, O. N. & Helin, K., 2015, In: Cell Research. 25, p. 1205-1218 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Trust is good, control is better: technical considerations in blood microbiome analysis

    Schierwagen, R., Alvarez Silva, Maria Camila, Servant, F., Trebicka, J., Lelouvier, B. & Arumugam, Mani, 2020, In: Gut. 69, 7, p. 1362-1363

    Research output: Contribution to journal › Letter › Research › peer-review

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