Novo Nordisk Foundation Center for Basic Metabolic Research

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  1. Published

    The potential role of SOCS-3 in the interleukin-1beta-induced desensitization of insulin signaling in pancreatic beta-cells

    Emanuelli, Brice, Glondu, M., Filloux, C., Peraldi, P. & Van Obberghen, E., Dec 2004, In: Diabetes. 53 Suppl 3, p. S97-S103

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    The potential of tailoring the gut microbiome to prevent and treat cardiometabolic disease

    Chakaroun, R. M., Olsson, L. M. & Bäckhed, F., 2023, In: Nature Reviews Cardiology. 20, p. 217-235

    Research output: Contribution to journal › Review › Research › peer-review

  3. Published

    The plasticity of NBS resistance genes in sorghum is driven by multiple evolutionary processes

    Mace, E., Tai, S., Innes, D., Godwin, I., Hu, W., Campbell, B., Gilding, E., Cruickshank, A., Prentis, P., Wang, J. & Jordan, D., 2014, In: B M C Plant Biology. 14, 14 p., 253.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    The physiology of obesity; from mechanisms to medicine. Part two

    Aldiss, Peter Stuart Jacob & Lewis, J. E., 2022, In: Journal of Physiology. 600, 5, p. 999-1000 2 p.

    Research output: Contribution to journal › Editorial › Research

  5. Published

    The physiology of obesity: from mechanisms to medicine (M2M). Part one

    Lewis, J. E. & Aldiss, Peter Stuart Jacob, 2022, In: Journal of Physiology. 600, 4, p. 697-698 2 p.

    Research output: Contribution to journal › Editorial › Research

  6. Published

    The physiology of experimental overfeeding in animals

    Ranea-Robles, Pablo, Lund, Jens & Clemmensen, Christoffer, 2022, In: Molecular Metabolism. 64, 15 p., 101573.

    Research output: Contribution to journal › Review › Research › peer-review

  7. Published

    The phosphorylation of AMPKβ1 is critical for increasing autophagy and maintaining mitochondrial homeostasis in response to fatty acids

    Desjardins, E. M., Smith, B. K., Day, E. A., Ducommun, S., Sanders, M. J., Nederveen, J. P., Ford, R. J., Pinkosky, S. L., Townsend, L. K., Gutgesell, R. M., Lu, R., Sakamoto, Kei & Steinberg, G. R., 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 48, 8 p., e2119824119.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    The next decade of metabolism

    Backhed, F., Bugianesi, E., Christofk, H., Dikic, I., Gupta, R., Mair, W. B., O'Neill, L. A. J., Ralser, M., Sabatini, D. M. & Tschop, M., 2019, In: Nature Metabolism. 1, p. 2-4

    Research output: Contribution to journal › Comment/debate › Research

  9. Published

    The new donor vigilance system in Denmark reveals regional differences in adverse reactions supposedly caused by variation in the registration

    Mikkelsen, Christina, Paarup, H. M., Bruun, M. T., Pedersen, L. Ø., Hasslund, S., Larsen, R., Aagaard, B. & Sørensen, B. S., 2022, In: Vox Sanguinis. 117, 3, p. 321-327

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    The naturally occurring GIP(1-30)NH2 is a GIP receptor agonist in humans

    Krogh, L. S. L., Henriksen, K., Stensen, S., Skov-Jeppesen, Kirsa, Bergmann, N. C., Størling, Joachim, Rosenkilde, Mette, Hartmann, Bolette, Holst, Jens Juul, Gasbjerg, Lærke Smidt & Knop, Filip Krag, 2023, In: European Journal of Endocrinology. 188, 1, lvac015.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    The national child odontology registry (SCOR): a valuable resource for odontological and public health research

    Nygaard, Nikoline, Ängquist, Lars, Midjord-Belstrøm, Daniel, Stankevic, Evelina, Hansen, Torben, Olsen, A., Rosing, Kasper & Markvart, Merete, 2023, In: BMC Oral Health. 23, 13 p., 608.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    The multifactorial and multistage character of protective immunity to Plasmodium falciparum, naturally acquired by an indigenous population in Burkina Faso

    Boudin, C., Sheick, I., Chumpitazi, B., Pazart, L., Høgh, Birthe, Peyron, F., Deloron, P., Picot, S. & Ambroise-Thomas, P., Apr 1994, In: Scandinavian Journal of Immunology. 39, 4, p. 409-17 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    The morphogenetic MreBCD proteins of Escherichia coli form an essential membrane-bound complex

    Kruse, Thomas, Bork-Jensen, J. & Gerdes, K., Jan 2005, In: Molecular Microbiology. 55, 1, p. 78-89 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    The minor C-allele of rs2014355 in ACADS is associated with reduced insulin release following an oral glucose load

    Hornbak, M., Banasik, Karina, Justesen, Johanne Marie, Krarup, N. T., Sandholt, C. H., Andersson, Åsa, Sandbaek, A., Lauritzen, T., Pisinger, C., Witte, D. R., Sørensen, Thorkild I.A., Pedersen, Oluf Borbye & Hansen, Torben, 6 Jan 2011, In: BMC Medical Genetics. 12, 1, p. 4 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    The microbiome of tunnels in hidradenitis suppurativa patients

    Ring, H. C., Sigsgaard, V., Thorsen, Jonathan Jan Ilve, Fuursted, K., Fabricius, S., Saunte, Ditte Marie & Jemec, Gregor, 2019, In: Journal of the European Academy of Dermatology and Venereology : JEADV. 33, 9, p. 1775-1780 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    The microbiome of captive hamadryas baboons

    Li, Xuan Ji, Trivedi, Urvish, Brejnrod, A. D., Vestergaard, G. A., Mortensen, M. S., Bertelsen, Mads Frost & Sørensen, Søren Johannes, 2020, In: BMC Animal Microbiome. 2, 10 p., 25.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    The metabolic actions of neurotensin secreted from the gut

    Ratner, C., Johnsen, Cecilie Hundahl & Holst, Birgitte, Sep 2016, In: Cardiovascular Endocrinology. 5, 3, p. 102-111

    Research output: Contribution to journal › Review › Research › peer-review

  18. Published

    The melanocortin-4 receptor is expressed in enteroendocrine L cells and regulates the release of peptide YY and glucagon-like peptide 1 in vivo

    Panaro, B. L., Tough, I. R., Engelstoft, M. S., Matthews, R. T., Digby, G. J., Møller, C. L., Svendsen, B., Gribble, F., Reimann, F., Holst, Jens Juul, Holst, Birgitte, Schwartz, Thue W., Cox, H. M. & Cone, R. D., 2 Dec 2014, In: Cell Metabolism. 20, 6, p. 1018-29 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    The liver–alpha cell axis associates with liver fat and insulin resistance: a validation study in women with non-steatotic liver fat levels

    Gar, C., Haschka, S. J., Kern-Matschilles, S., Rauch, B., Sacco, V., Prehn, C., Adamski, J., Seissler, J., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul & Lechner, A., 2021, In: Diabetologia. 64, 3, p. 512-520

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    The liver-alpha-cell axis after a mixed meal and during weight loss in type 2 diabetes

    Otten, J., Stomby, A., Waling, M., Chorell, E., Ryberg, M., Svensson, M., Holst, Jens Juul & Olsson, T., 2021, In: Endocrine Connections. 10, 9, p. 1101-1110

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    The liver-alpha cell axis and type 2 diabetes

    Albrechtsen, Nicolai Jacob Wewer, Pedersen, Jens, Galsgaard, Katrine Douglas, Winther-Sørensen, Marie, Suppli, M. P., Janah, L., Gromada, J., Vilstrup, H., Knop, Filip Krag & Holst, Jens Juul, 2019, In: Endocrine Reviews. 40, 5, p. 1353-1366

    Research output: Contribution to journal › Review › Research › peer-review

  22. Published

    The levelling off of the obesity epidemic since the year 1999--a review of evidence and perspectives

    Rokholm, B., Baker, J. L. & Sørensen, Thorkild I.A., 1 Dec 2010, In: Obesity Reviews. 11, 12, p. 835-46 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    The legacy of our ancestors' lifestyle

    Barrès, Romain, 2016, In: Biochemist. 38, 2, p. 1-4 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    The lack of natural processes of delivery and neonatal intensive care treatment lead to impaired cytokine responses later in life

    Martikainen, M. V., Keski-Nisula, L., Jakupovic, Hermina, Karvonen, A. M., Pekkanen, J., Hirvonen, M. R. & Roponen, M., 1 Mar 2017, In: American Journal of Reproductive Immunology. 77, 3, e12621.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    The isoenzyme pattern of LDH does not play a physiological role; except perhaps during fast transitions in energy metabolism

    Quistorff, B. & Grunnet, N., 2011, In: Aging. 3, 5, p. 457-460

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    The intracellular to extracellular proton gradient following maximal whole body exercise and its implication for anaerobic energy production

    Voiantis, S., Secher, Niels H. & Quistorff, B., Aug 2010, In: European Journal of Applied Physiology. 109, 6, p. 1171-1177 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    The intestinotrophic peptide, GLP-2, counteracts the gastrointestinal atrophy in mice induced by the epidermal growth factor receptor inhibitor, erlotinib, and cisplatin

    Rasmussen, A. R., Viby, N., Hare, K. J., Hartmann, Bolette, Thim, L., Holst, Jens Juul & Poulsen, Steen Seier, 1 Oct 2010, In: Digestive Diseases and Sciences. 55, 10, p. 2785-96 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    The intestinal microbiome is a co-determinant of the postprandial plasma glucose response

    Søndertoft, N. B., Vogt, J. K., Arumugam, Mani, Kristensen, M., Gøbel, R. J., Fan, Yong, Lyu, Liwei, Bahl, M. I., Eriksen, C., Ängquist, Lars, Frøkiær, Hanne, Hansen, T. H., Brix, Susanne, Nielsen, H. B., Hansen, Torben, Vestergaard, H., Gupta, R., Licht, T. R., Lauritzen, Lotte & Pedersen, Oluf Borbye, 2020, In: P L o S One. 15, 9, 23 p., e0238648.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    The intestinal distribution pattern of appetite- and glucose regulatory peptides in mice, rats and pigs

    Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Toräng, S. & Holst, Jens Juul, 2 Feb 2016, In: BMC Research Notes. 9, 1, p. 1-6 6 p., 60.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    The interleukin-1 receptor antagonist anakinra improves first-phase insulin secretion and insulinogenic index in subjects with impaired glucose tolerance

    van Poppel, P. C. M., van Asseldonk, E. J. P., Holst, Jens Juul, Vilsbøll, Tina, Netea, M. G. & Tack, C. J., Dec 2014, In: Diabetes, Obesity and Metabolism. 16, 12, p. 1269-73 5 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  31. Published

    The interaction between the adaptor protein APS and Enigma is involved in actin organisation

    Barrès, Romain, Gonzalez, T., Le Marchand-Brustel, Y. & Tanti, J., 15 Aug 2005, In: Experimental Cell Research. 308, 2, p. 334-44 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    The insulinotropic effect of exogenous GLP-1 is not affected by acute vagotomy in anaesthetized pigs

    Veedfald, Simon, Hansen, M., Christensen, L. W., Larsen, S. A. H., Hjøllund, K. R., Plamboeck, A., Hartmann, Bolette, Deacon, Carolyn F. & Holst, Jens Juul, 30 Mar 2016, In: Experimental Physiology. 101, 7, p. 895-912 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    The insulinogenic effect of whey protein is partially mediated by a direct effect of amino acids and GIP on β-cells

    Salehi, A., Gunnerud, U., Muhammed, S. J., Ostman, E., Holst, Jens Juul, Björck, I. & Rorsman, P., 2012, In: Nutrition & Metabolism. 9, 1, p. 48

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    The influence of transmitted and non-transmitted parental BMI-associated alleles on the risk of overweight in childhood

    Schnurr, T. M., Morgen, C. S., Borisevich, D., Beaumont, R. N., pjx571, pjx571, Ängquist, Lars, Have, C. T., Freathy, R. M., Smith, G. D., Nohr, E. A., Hansen, Torben & Sørensen, Thorkild I.A., 2020, In: Scientific Reports. 10, 1, 10 p., 4806.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    The influence of persistent organic pollutants in the traditional Inuit diet on markers of inflammation

    Schæbel, L. K., Bonefeld-Jørgensen, E. C., drb459, drb459 & Andersen, S., 2017, In: PLOS ONE. 12, 5, 16 p., e0177781.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    The influence of parental history of diabetes and offspring birthweight on offspring glucose metabolism in adulthood

    Lauenborg, J., Jørgensen, M. K., Damm, Peter, Major-Pedersen, A., Eiberg, Hans Rudolf Lytchoff, Urhammer, S., Pedersen, Oluf Borbye & Hansen, Torben, Dec 2011, In: Acta Obstetricia et Gynecologica Scandinavica. 90, 12, p. 1357-1363 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    The influence of insulin-related genetic variants on fetal growth, fetal blood flow, and placental weight in a prospective pregnancy cohort

    Reim, Pauline Kromann, pjx571, pjx571, Gybel-Brask, D., Schnurr, T. M., Kelstrup, Louise, Høgdall, Estrid Vilma Solyom & Hansen, Torben, 2023, In: Scientific Reports. 13, 10 p., 19638.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    The influence of glucagon on postprandial hyperglycaemia in children 5 years after onset of type 1 diabetes

    Fredheim, S., Andersen, M. M., Pörksen, S., Nielsen, L. B., Pipper, C., Hansen, L., Holst, Jens Juul, Thomsen, J., Johannesen, Jesper, Mortensen, H. B. & Svensson, Jannet, 2015, In: Diabetologia. 58, 4, p. 828-34 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    The independent effect of type 2 diabetes mellitus on ischemic heart disease, stroke, and death: a population-based study of 13,000 men and women with 20 years of follow-up

    Almdal, Thomas Peter, Scharling, H., Jensen, J. S. & drb459, drb459, 12 Jul 2004, In: J A M A Internal Medicine. 164, 13, p. 1422-6 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    The incretin/glucagon system as a target for pharmacotherapy of obesity

    Del Prato, S., Gallwitz, B., Holst, Jens Juul & Meier, J. J., 2022, In: Obesity Reviews. 23, 2, 13 p., e13372.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    The incretin system in healthy humans: The role of GIP and GLP-1

    Holst, Jens Juul, 2019, In: Metabolism. 96, p. 46-55

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    The incretin effect in patients with maturity onset diabetes of the young

    Ostoft, S. H., Bagger, J. I., Hansen, T., Pedersen, O., Holst, Jens Juul, Knop, Filip Krag & Vilsboll, T., 2012, In: Diabetologia. 55, p. S144-S144

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    The incretin effect does not differ in trained and untrained, young, healthy men

    Lund, M. T., Dalby, S., Hartmann, Bolette, Helge, Jørn Wulff, Holst, Jens Juul & Dela, Flemming, Mar 2014, In: Acta Physiologica. 210, 3, p. 565-72 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    The importance of glucose-dependent insulinotropic polypeptide receptor activation for the effects of tirzepatide

    Gasbjerg, Lærke Smidt, Rosenkilde, Mette, Meier, J. J., Holst, Jens Juul & Knop, Filip Krag, 2023, In: Diabetes, Obesity and Metabolism. 25, 11, p. 3079-3092

    Research output: Contribution to journal › Review › Research › peer-review

  45. Published

    The importance of endogenously secreted GLP-1 and GIP for postprandial glucose tolerance and β-cell function after Roux-en-Y gastric bypass and sleeve gastrectomy surgery

    Hindsø, M., Hedbäck, N., Svane, M. S., Møller, A., Martinussen, C., Jørgensen, N. B., Dirksen, C., Gasbjerg, Lærke Smidt, Kristiansen, V. B., Hartmann, Bolette, Rosenkilde, Mette, Holst, Jens Juul, Madsbad, Sten & Bojsen-Møller, K. N., 2023, In: Diabetes. 72, 3, p. 336–347

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    The impact of surgery and oncological treatment on risk of type 2 diabetes onset in patients with colorectal cancer: nationwide cohort study in Denmark

    Krag, C., Svane, M. S., Madsbad, Sten, Graversen, S. B., Christensen, J. F., Sørensen, Thorkild I.A., Lehrskov, L. L. & Laurberg, T., 2024, In: eLife. 12, 13 p., RP89354.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    The impact of short chain fatty acids on GLP-1 and PYY secretion from the isolated perfused rat colon

    Christiansen, Charlotte Bayer, Gabe, M. B. N., Svendsen, B., Dragsted, Lars Ove, Rosenkilde, Mette & Holst, Jens Juul, 2018, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 315, 1, p. G53-G65 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    The impact of dipeptidyl peptidase 4 inhibition on incretin effect, glucose tolerance, and gastrointestinal-mediated glucose disposal in healthy subjects

    Rhee, N. A., Østoft, S. H., Holst, Jens Juul, Deacon, Carolyn F., Vilsbøll, T. & Knop, Filip Krag, 16 Jun 2014, In: European Journal of Endocrinology. 171, 3, p. 353-362 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    The impact of anorexia nervosa and BMI polygenic risk on childhood growth: A 20-year longitudinal population-based study

    Abdulkadir, M., Hübel, C., Herle, M., Loos, Ruth, Breen, G., Bulik, C. M. & Micali, N., 2022, In: American Journal of Human Genetics. 109, 7, p. 1242-1254 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    The impact of acute glycaemic fluctuations on left ventricular systolic function in insulin-treated type 2 diabetes

    Andersen, A., Jorgensen, P. G., Bagger, J. I., Baldassarre, M. P. A., Christensen, M., Abelin, K. U., Faber, Jens, Pedersen-Bjergaard, Ulrik, Holst, Jens Juul, Lindhardt, T., Gislason, Gunnar Hilmar, Knop, Filip Krag & Vilsbøll, Tina, 2020, In: Diabetologia. 63, SUPPL 1, p. S429-S429 897.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

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