Novo Nordisk Foundation Center for Basic Metabolic Research

  1. Published

    Circulating Levels of the Soluble Receptor for AGE (sRAGE) during Escalating Oral Glucose Dosages and Corresponding Isoglycaemic i.v. Glucose Infusions in Individuals with and without Type 2 Diabetes

    Fotheringham, A. K., Bagger, J. I., Borg, D. J., McCarthy, D. A., Holst, Jens Juul, Vilsbøll, Tina, Knop, Filip Krag & Forbes, J. M., 2020, In: Nutrients. 12, 10, 12 p., 2928.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production

    Albrechtsen, N. J. W., Kuhre, R. E., Hornburg, D., Jensen, C. Z., Hornum, M., Dirksen, C., Svane, M., Gasbjerg, L. S., Jorgensen, N. B., Gabe, M. N., Balk-Moller, E., Albrechtsen, R., Winther-Sorensen, M., Galsgaard, K. D., Meissner, F., Jorsal, T., Lund, A., Vilsboll, T., Eliasen, R., Bojsen-Moller, K. N. & 9 others, Idorn, T., Deacon, Carolyn F., Knop, Filip Krag, Rosenkilde, Mette, Hartmann, Bolette, Feldt-Rasmussen, Bo, Mann, Matthias, Madsbad, Sten & Holst, Jens Juul, Nov 2017, In: Cell Reports. 21, 6, p. 1452-1460

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Circulating Amino Acids and Risk of Peripheral Artery Disease in the PREDIMED Trial

    Razquin, C., Ruiz-Canela, M., Toledo, E., Clish, C. B., Guasch-Ferré, M., García-Gavilán, J. F., Wittenbecher, C., Alonso-Gómez, A., Fitó, M., Liang, L., Corella, D., Gómez-Gracia, E., Estruch, R., Fiol, M., Santos-Lozano, J. M., Serra-Majem, L., Ros, E., Aros, F., Salas-Salvadó, J., Hu, F. B. & 1 others, Martínez-González, M. A., 2023, In: International Journal of Molecular Sciences. 24, 12 p., 270.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Circadian rhythms and exercise - re-setting the clock in metabolic disease

    Gabriel, B. M. & Zierath, Juleen R, 2019, In: Nature Reviews Endocrinology. 15, 4, p. 197-206

    Research output: Contribution to journalReviewResearchpeer-review

  5. Published

    Circadian enhancers coordinate multiple phases of rhythmic gene transcription in vivo

    Fang, B., Everett, L. J., Jager, J., Briggs, E., Armour, S. M., Feng, D., Roy, A., Gerhart-Hines, Zach, Sun, Z. & Lazar, M. A., 20 Nov 2014, In: Cell. 159, 5, p. 1140-1152 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Circadian Metabolism in the Light of Evolution

    Gerhart-Hines, Zach & Lazar, M. A., 2015, In: Endocrine Reviews. 36, 3, p. 289-304 16 p.

    Research output: Contribution to journalReviewResearchpeer-review

  7. Published

    Chronotype, Unhealthy Lifestyle, and Diabetes Risk in Middle-Aged U.S. Women: A Prospective Cohort Study

    Kianersi, S., Liu, Y., Guasch Ferre, Marta, Redline, S., Schernhammer, E., Sun, Q. & Huang, T., 2023, In: Annals of Internal Medicine. 176, 10, p. 1330-1339 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Chrono-nutrition for the prevention and treatment of obesity and type 2 diabetes: from mice to men

    Hawley, J. A., Sassone-Corsi, P. & Zierath, Juleen R, 2020, In: Diabetologia. 63, 11, p. 2253-2259 7 p.

    Research output: Contribution to journalReviewResearchpeer-review

  9. Published

    Chronic sympathetic activation promotes downregulation of ß-adrenoceptor-mediated effects in the guinea pig heart independently of structural remodeling and systolic dysfunction

    Soltysinska, E., Thiele, S., Osadchiy, O. & Olesen, Søren-Peter, 2011, In: Pflügers Archiv - European Journal of Physiology. 462, 4, p. 529-43 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Chronic intrahypothalamic rather than subcutaneous liraglutide treatment reduces body weight gain and stimulates the melanocortin receptor system

    Kaineder, K., Birngruber, T., Rauter, G., Obermüller, B., Eichler, J., Münzker, J., Al-Zoughbi, W., Mautner, S. I., Torekov, Signe Sørensen, Hartmann, Bolette, Kotzbeck, P. & Pieber, T. R., 16 May 2017, In: International Journal of Obesity. 41, p. 1263-1270 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Chronic high-fat diet in fathers programs ß-cell dysfunction in female rat offspring

    Ng, S., Lin, R. C. Y., Laybutt, D. R., Barrès, Romain, Owens, J. A. & Morris, M. J., 21 Oct 2010, In: Nature. 467, 7318, p. 963-6 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Chronic high dose P2X7 receptor inhibition exacerbates cancer-induced bone pain

    Falk, S., Appel, C. K., Bennedbæk, H. B., Al-Dihaissy, T., Unger, A., Dinkel, K. & Heegaard, Anne-Marie, 15 Feb 2019, In: European Journal of Pharmacology. 845, p. 48-55 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Chronic glucocorticoid treatment increases de novo lipogenesis in visceral adipose tissue

    Vienberg, S. G. & Björnholm, M., Jun 2014, In: Acta Physiologica (Print). 211, 2, p. 257-9 3 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  14. Published

    Chronic family stress moderates the association between a TOMM40 variant and triglyceride levels in two independent Caucasian samples

    Jiang, R., Brummett, B. H., Hauser, E. R., Babyak, M. A., Siegler, I. C., Singh, A., Astrup, A., Pedersen, Oluf Borbye, Hansen, T., Holst, C., Sørensen, Thorkild I.A. & Williams, R. B., 2013, In: Biological Psychology. 93, 1, p. 184-189 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Chronic erythropoietin treatment improves diet-induced glucose intolerance in rats

    Caillaud, C., Mechta, Mie, Ainge, H., Madsen, A. N., Ruell, P., Mas, E., Bisbal, C., Mercier, J., Twigg, S., Mori, T. A., Simar, D. & Barrès, Romain, 2015, In: Journal of Endocrinology. 225, 2, p. 77-88 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Chronic care treatment of obese children and adolescents

    Holm, Jens-Christian, Gamborg, M., Bille, D. S., Gr Nb K, H. N., Ward, L. C. & Faerk, J., Aug 2011, In: International journal of pediatric obesity : IJPO : an official journal of the International Association for the Study of Obesity. 6, 3-4, p. 188-96 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published
  18. Published

    Chromosomal mapping and mutational analysis of the coding region of the glycogen synthase kinase-3alpha and beta isoforms in patients with NIDDM

    Hansen, L., Arden, K. C., Rasmussen, S. B., Viars, C. S., drb459, drb459, Hansen, Teis Schjals, Møller, A. M., Woodgett, J. R. & Pedersen, Oluf Borbye, Aug 1997, In: Diabetologia. 40, 8, p. 940-6 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Cholestasis alters brain lipid and bile acid composition and compromises motor function in neonatal piglets

    Henriksen, Nicole Lind, Hansen, S. H., Lycas, M. D., Pan, X., Eriksen, Thomas, Johansen, L. S., Sprenger, R. R., Ejsing, C. S., Burrin, D. G., Skovgaard, K., Christensen, Vibeke Brix, Thymann, Thomas & Pankratova, Stanislava, 2022, In: Physiological Reports. 10, 13, 15 p., e15368.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Cholecystokinin-Induced Gallbladder Emptying and Single-Dose Metformin Elicit Additive Glucagon-Like Peptide-1 Responses

    Rohde, U., Sonne, D. P., Christensen, M., Hansen, M., Brønden, A., Toräng, S., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 1 May 2016, In: The Journal of clinical endocrinology and metabolism. 101, 5, p. 2076-2083

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Cholecystokinin secretion is suppressed by glucagon-like peptide-1: clue to the mechanism of the adverse gallbladder events of GLP-1-derived drugs

    Rehfeld, Jens Frederik, Knop, Filip Krag, Asmar, A., Madsbad, Sten, Holst, Jens Juul & Asmar, M., 2018, In: Scandinavian Journal of Gastroenterology. 53, 12, p. 1429-1432

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Cholecystokinin is a negative regulator of gastric acid secretion and postprandial release of gastrin in humans.

    Schmidt, W. E., Schenk, S., Nustede, R., Rovati, L. C., Holst, Jens Juul, Fölsch, U. & Creutzfeldt, W., 1994, In: Today in Medicine. Gastroenterology. 107, p. 1610-1620

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Childhood overweight after establishment of the gut microbiota: the role of delivery mode, pre-pregnancy weight and early administration of antibiotics

    Adeltoft, T. A., Andersen, C. S., Gamborg, Michael Orland, Sørensen, Thorkild I.A. & Riis, J. T., 1 Apr 2011, In: International Journal of Obesity. 35, 4, p. 522-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Childhood obesity treatment; Effects on BMI SDS, body composition, and fasting plasma lipid concentrations

    Nielsen, T. R. H., Fonvig, Cilius Esmann, Dahl, M., Mollerup, P. M., Lausten-Thomsen, U., Pedersen, Oluf Borbye, Hansen, Torben & Holm, Jens-Christian, 2018, In: P L o S One. 13, 2, p. 1-18 18 p., e0190576.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Childhood maltreatment and obesity

    Sørensen, Thorkild I.A., Aug 2015, In: Obesity. 23, 8, p. 1528 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  26. Published

    Childhood height, adult height, and the risk of prostate cancer

    Bjerregaard, L. G., Aarestrup, J., Gamborg, Michael Orland, Lange, Theis, Tjønneland, A. & Baker, J. L., Apr 2016, In: Cancer Causes & Control. 27, 4, p. 561-567 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Childhood height increases the risk of prostate cancer mortality

    Aarestrup, J., Gamborg, Michael Orland, Cook, M. B. & Baker, J. L., Jul 2015, In: European Journal of Cancer. 51, 10, p. 1340-1345 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Childhood height and risk of testicular germ cell tumors in adulthood

    McGlynn, K. A., Petrick, J. L., Gamborg, Michael Orland, Aarestrup, J. & Baker, J. L., 2019, In: International Journal of Cancer. 143, 4, p. 767-772 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Childhood growth and risk of inflammatory bowel disease: a population-based study of 317,030 children

    Mendall, M., Jensen, C. B., Ängquist, Lars, Baker, J. L. & Jess, T., 2019, In: Scandinavian Journal of Gastroenterology. 54, 7, p. 863-868

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Childhood body mass index in relation to subsequent risk of type 1 diabetes-A Danish cohort study

    Antvorskov, J. C., Aunsholt, L., Buschard, K., Gamborg, Michael Orland, Kristensen, K., Johannesen, Jesper, Sørensen, Thorkild I.A. & Svensson, Jannet, Mar 2018, In: Pediatric Diabetes. 19, 2, p. 265-270 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Childhood body mass index in relation to future risk of oesophageal adenocarcinoma

    Cook, M. B., Freedman, N. D., Gamborg, Michael Orland, Sørensen, Thorkild I.A. & Baker, J. L., 2015, In: B J C. 112, p. 601-607 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Childhood body mass index and the risk of prostate cancer in adult men

    Aarestrup, J., Gamborg, Michael Orland, Cook, M. B., Sørensen, Thorkild I.A. & Baker, J. L., 2014, In: B J C. 111, p. 207-212 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Childhood body mass index and risk of schizophrenia in relation to childhood age, sex and age of first contact with schizophrenia

    Sørensen, H. J., Gamborg, Michael Orland, Sørensen, Thorkild I.A., Baker, J. L. & Mortensen, Erik Lykke, Apr 2016, In: European Psychiatry. 34, p. 64-9 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Childhood body mass index and risk of inflammatory bowel disease in adulthood: a population-based cohort study

    Jensen, C. B., Ängquist, Lars, Mendall, M. A., Sørensen, Thorkild I.A., Baker, J. L. & Jess, T., 2018, In: The American Journal of Gastroenterology. 113, 5, p. 694-701 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Childhood body mass index and risk of adult pancreatic cancer

    Nogueira, L., Stolzenberg-Solomon, R., Gamborg, Michael Orland, Sørensen, Thorkild I.A. & Baker, J. L., Oct 2017, In: Current Opinion in Clinical Nutrition and Metabolic Care. 1, 10, 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Childhood body mass index and multiple sclerosis risk: a long-term cohort study

    Munger, K. L., Bentzen, J., Laursen, B., Stenager, E., Koch-Henriksen, N. I., Sørensen, Thorkild I.A. & Baker, J. L., 2013, In: Multiple Sclerosis. 19, 10, p. 1323-1329 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Childhood body mass index and height in relation to site-specific risks of colorectal cancers in adult life

    Jensen, B. W., Gamborg, M., Gögenur, Ismail, Renehan, A. G., Sørensen, Thorkild I.A. & Baker, J. L., Dec 2017, In: European Journal of Epidemiology. 32, 12, p. 1097-1106

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Childhood body mass index and height and risk of histologic subtypes of endometrial cancer

    Aarestrup, J., Gamborg, Michael Orland, Ulrich, L. G., Sørensen, Thorkild I.A. & Baker, J. L., 2016, In: International Journal of Obesity. 40, p. 1096-1102 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Childhood body mass index and development of type 2 diabetes throughout adult life: A large-scale danish cohort study

    Zimmermann, E., Bjerregaard, L. G., Gamborg, M., Vaag, Allan, Sørensen, Thorkild I.A. & Baker, J. L., 2017, In: Obesity. 25, 5, p. 965-971

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. E-pub ahead of print

    Childhood adversity trajectories and weight status in young adult men: a register-based study including 359,783 Danish men

    Wimmelmann, Cathrine Lawaetz, Sejling, Christoffer, Clarke, Rebecca B, Elsenburg, Leonie K., Sørensen, Thorkild I.A. & Rod, Naja Hulvej, 2024, (E-pub ahead of print) In: International journal of obesity (2005).

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Childhood Stature and Growth in Relation to First Ischemic Stroke or Intracerebral Hemorrhage

    Gjærde, L. K., Truelsen, T. C. & Baker, J. L., Mar 2018, In: Stroke. 49, 3, p. 579-585

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Childhood Overweight, Tallness, and Growth Increase Risks of Ovarian Cancer

    Aarestrup, J., Trabert, B., Ulrich, L. G., Wentzensen, N., Sørensen, Thorkild I.A. & Baker, J. L., 2019, In: Cancer Epidemiology, Biomarkers & Prevention. 28, 1, p. 183-188

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Childhood Obesity at the Crossroads of Science and Social Justice

    Ludwig, D. S. & Holst, Jens Juul, 2023, In: JAMA. 329, 22, p. 1909-1910

    Research output: Contribution to journalEditorialResearch

  44. Published

    Childhood Height and Body Mass Index Were Associated with Risk of Adult Thyroid Cancer in a Large Cohort Study

    Kitahara, C. M., Gamborg, Michael Orland, Berrington de González, A., Sørensen, Thorkild I.A. & Baker, J. L., 1 Jan 2014, In: Cancer Research. 74, 1, p. 235-242 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Childhood Height and Birth Weight in Relation to Future Prostate Cancer Risk: A Cohort Study Based on the Copenhagen School Health Records Register

    Cook, M. B., Gamborg, M., Aarestrup, J., Sørensen, Thorkild I.A. & Baker, J. L., Dec 2013, In: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 22, 12, p. 2232-2240 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Childhood Body Size and the Risk of Malignant Melanoma in Adulthood

    Meyle, K. D., Gamborg, Michael Orland, Sørensen, Thorkild I.A. & Baker, J. L., 15 Apr 2017, In: American Journal of Epidemiology. 185, 8, p. 673-680 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Childhood BMI growth trajectories and endometrial cancer risk

    Aarestrup, J., Gamborg, M., Tilling, K., Ulrich, L. G., Sørensen, Thorkild I.A. & Baker, J. L., 15 Jan 2017, In: International Journal of Cancer. 140, 2, p. 310–315 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Child-to-adult body size change and risk of type 2 diabetes and cardiovascular disease

    Carrasquilla, Germán D., Ängquist, Lars, Sørensen, Thorkild I.A., Kilpeläinen, Tuomas O. & Loos, Ruth, 2024, In: Diabetologia. 67, p. 864–873 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Child overweight - mothers' competence to take action

    Brødsgaard, A., Wagner, L., Peitersen, B., Poulsen, I. & Sørensen, Thorkild I.A., Aug 2011, In: Obesity Facts. 4, 4, p. 305-11 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Chenodeoxycholic acid stimulates glucagon-like peptide-1 secretion in patients after Roux-en-Y gastric bypass

    Nielsen, S., Svane, M. S., Kuhre, Rune Ehrenreich, Clausen, T. R., Kristiansen, V. B., Rehfeld, Jens Frederik, Holst, Jens Juul, Madsbad, Sten & Bojsen-Moller, K. N., Feb 2017, In: Physiological Reports. 5, 3, 11 p., e13140.

    Research output: Contribution to journalJournal articleResearchpeer-review