Novo Nordisk Foundation Center for Basic Metabolic Research

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  1. Published

    Cardiovascular effects of incretins - focus on glucagon-like peptide-1 receptor agonists

    Madsbad, Sten & Holst, Jens Juul, 2023, In: Cardiovascular Research. p. 886–904 19 p.

    Research output: Contribution to journal › Review › Research › peer-review

  2. Published

    Cardiovascular effects of high-dose glucagon: a randomised clinical trial

    Petersen, K. M., Bogevig, S., Riis, T., Andersson, N. A. W., Dalhoff, Kim, Holst, Jens Juul, Knop, Filip Krag, Faber, Jens, Petersen, Tonny Studsgaard & Christensen, Mikkel Bring, 2020, In: Diabetologia. 63, SUPPL 1, p. S231-S231

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  3. Published

    Cardiovascular biomarkers in clinical studies of type 2 diabetes

    Baldassarre, M. P. A., Andersen, A., Consoli, A., Knop, Filip Krag & Vilsbøll, Tina, 2018, In: Diabetes, Obesity and Metabolism. 20, 6, p. 1350-1360

    Research output: Contribution to journal › Review › Research › peer-review

  4. Published

    Cardiovascular and All-Cause Mortality Risk Associated With Urinary Excretion of 8-oxoGuo, a Biomarker for RNA Oxidation, in Patients With Type 2 Diabetes: A Prospective Cohort Study

    Kjær, L. K., Cejvanovic, V., Henriksen, T., Petersen, K. M., Hansen, Torben, Pedersen, Oluf Borbye, Christensen, C. K., Torp-Pedersen, C., Gerds, Thomas Alexander, Brandslund, I., Mandrup-Poulsen, Thomas & Poulsen, Henrik Enghusen, Dec 2017, In: Diabetes Care. 40, 12, p. 1771-1778 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Cardiovascular Risk Profile Among Patients With Inflammatory Bowel Disease: A Population-based Study of More Than 100 000 Individuals

    Aarestrup, J., Jess, T., Kobylecki, C. J., Nordestgaard, Børge & Allin, K. H., 2019, In: Journal of Crohn's and Colitis. 13, 3, p. 319-323 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Cardiorespiratory Fitness and Adiposity as Determinants of Metabolic Health-Pooled Analysis of Two Twin Cohorts

    Jukarainen, S., Holst, R., Dalgård, C., Piirilä, P., Lundbom, J., Hakkarainen, A., Lundbom, N., Rissanen, A., Kaprio, J., Kyvik, K. O., Sørensen, Thorkild I.A. & Pietiläinen, K. H., 1 May 2017, In: The Journal of clinical endocrinology and metabolism. 102, 5, p. 1520-1528 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis

    Sustarsic, E. G., Ma, T., Lynes, M. D., Larsen, M., Karavaeva, I., Havelund, J. F., Nielsen, C. H., Jedrychowski, M. P., Moreno-Torres, M., Lundh, M., Plucinska, K., Jespersen, N. Z., Grevengoed, T. J., Kramar, B., Peics, J., Hansen, J. B., Shamsi, F., Forss, I., Neess, D., Keipert, S. & 24 others, Wang, J., Stohlmann, K., Brandslund, I., Christensen, C., Jørgensen, M. E., Linneberg, Allan René, Pedersen, Oluf Borbye, Kiebish, M. A., Qvortrup, Klaus, Han, X., Pedersen, Bente Klarlund, Jastroch, M., Mandrup, S., Kjær, Andreas, Gygi, S. P., Hansen, Torben, Gillum, M. P., Grarup, N., Emanuelli, Brice, Nielsen, S., Schéele, Camilla Charlotte Nielsen, Tseng, Y., Færgeman, N. J. & Gerhart-Hines, Zach, 2018, In: Cell Metabolism. 28, 1, p. 159-174.e11

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Carboxypeptidase-B-like processing of the C-terminus of glucagon-like peptide-2 in pig and human small intestine

    Ørskov, Cathrine, Buhl, T., Rabenhøj, L., Kofod, H. & Holst, Jens Juul, 24 Apr 1989, In: F E B S Letters. 247, 2, p. 193-6 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Carbon source availability drives nutrient utilization in CD8+ T cells

    Kaymak, I., Luda, Katarzyna Maria, Duimstra, L. R., Ma, E. H., Longo, J., Dahabieh, M. S., Faubert, B., Oswald, B. M., Watson, M. J., Kitchen-Goosen, S. M., DeCamp, L. M., Compton, S. E., Fu, Z., DeBerardinis, R. J., Williams, K. S., Sheldon, R. D. & Jones, R. G., 2022, In: Cell Metabolism. 34, 9, p. 1298-1311 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Capturing Epidemics: Photographs by Howalt

    Tybjerg, Karin, Scott-Fordsmand, Helene & Howalt, N., 2020

    Research output: Non-textual form › 2D/3D (psysical products) › Research

  11. Published

    Cannabinoid receptor 1 antagonist genistein attenuates marijuana-induced vascular inflammation

    Wei, T-T., Chandy, M., Nishiga, M., Zhang, A., Kumar, K. K., Thomas, D., Manhas, A., Rhee, S., Justesen, J. M., Chen, I. Y., Wo, H-T., Khanamiri, S., Yang, J. Y., Seidl, F. J., Burns, N. Z., Liu, C., Sayed, N., Shie, J-J., Yeh, C-F., Yang, K-C. & 5 others, Lau, E., Lynch, K. L., Rivas, M., Kobilka, B. K. & Wu, J. C., 2022, In: Cell. 185, 10, p. 1676-1693.e23

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Cancer risk by combined levels of YKL-40 and C-reactive protein in the general population

    Allin, K. H., Bojesen, Stig Egil, Johansen, Julia Sidenius & Nordestgaard, Børge, 3 Jan 2012, In: B J C. 106, 1, p. 199-205 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Cancer and Pain

    Hansen, R. B. & Falk, S., Nov 2018, The Oxford Handbook of the Neurobiology of Pain. Oxford University Press

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  14. Published

    Canagliflozin or acarbose versus placebo to ameliorate post-bariatric hypoglycaemia - The HypoBar I randomized clinical trial protocol

    Lobato, C. B., wql596, wql596, Bojsen-Møller, Kirstine Nyvold, Martinussen, C., Veedfald, Simon, Holst, Jens Juul, Madsbad, Sten, Jørgensen, N. B. & Dirksen, Carsten Moro, 2024, In: Diabetic Medicine. 41, 6, 8 p., e15320.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Can we target obesity using a single-cell atlas of adipose tissue?

    Schéele, Camilla Charlotte Nielsen & Nielsen, S., 2022, In: Med. 3, 5, p. 276-278 3 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  16. Published

    Can breastfeeding promote an antibiotic-resilient microbiome?

    Stokholm, Jakob & Thorsen, Jonathan Jan Ilve, 2023, In: Med. 4, 2, p. 67-68 2 p.

    Research output: Contribution to journal › Comment/debate › Research

  17. Published

    Can Metabolite and Hormone Profiles Provide a Rationale for Choosing Between Bariatric Procedures?

    Guimarães, M., Pereira, S. S., Holst, Jens Juul, Nora, M. & Monteiro, M. P., 2021, In: Obesity Surgery. 31, p. 2174-2179

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Calsyntenin 3β Is Dynamically Regulated by Temperature in Murine Brown Adipose and Marks Human Multilocular Fat

    Plucinska, Kaja, Jespersen, N. Z., Brown, E. L., Petersen, P. S., Rupar, K., Nielsen, S., Schéele, Camilla Charlotte Nielsen & Emanuelli, Brice, 2020, In: Frontiers in Endocrinology. 11, 7 p., 579785.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Calorie restriction prevents diet-induced insulin resistance independently of PGC-1-driven mitochondrial biogenesis in white adipose tissue

    Pardo, R., Vila, M., Cervela, L., de Marco, M., Gama-Perez, P., Gonzalez-Franquesa, A., Statuto, L., Vilallonga, R., Simo, R., Garcia-Roves, P. M. & Villena, J. A., 2019, In: FASEB Journal. 33, 2, p. 2343-2358

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Calcium-sensing beyond neurotransmitters: functions of synaptotagmins in neuroendocrine and endocrine secretion

    Gustavsson, N. & Han, W., Aug 2009, In: Bioscience Reports. 29, 4, p. 245-59 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Calcium sensing in exocytosis

    Gustavsson, N., Wu, B. & Han, W., 2012, In: Advances in Experimental Medicine and Biology. 740, p. 731-57 27 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Calcitonin gene-related peptide: effect on contractile activity and luminal-cross-sectional area in isolated, perfused porcine ileum

    Rasmussen, T. N., Gregersen, H., Harling, H. & Holst, Jens Juul, 1993, In: Scandinavian Journal of Gastroenterology. 27, p. 787-792

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Calcitonin gene-related peptide (CGRP) in the nipple of the rat mammary gland

    Thulesen, J., Rasmussen, T. N., Schmidt, P., Holst, Jens Juul & Poulsen, Steen Seier, Dec 1994, In: Histochemistry. 102, 6, p. 437-444 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    CaMKK2 is not involved in contraction-stimulated AMPK activation and glucose uptake in skeletal muscle

    Negoita, F., Addinsall, A. B., Hellberg, K., Bringas, C. F., Hafen, P. S., Sermersheim, T. J., Agerholm, M., Lewis, C. T. A., Ahwazi, D., Ling, N. X. Y., Larsen, J. K., Deshmukh, A. S., Hossain, M. A., Oakhill, J. S., Ochala, J., Brault, J. J., Sankar, U., Drewry, D. H., Scott, J. W., Witczak, C. A. & 1 others, Sakamoto, Kei, 2023, In: Molecular Metabolism. 75, 14 p., 101761.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    CRTH2 receptor ligands for therapeutic use - B-series

    Ulven, Trond, Frimurer, Thomas Michael, Rist, Ø., Kostenis, E. & Högberg, T., 2005, Patent No. WO 2005/115374 A1

    Research output: Patent

  26. Published

    CRTH2 receptor ligands for therapeutic use

    Ulven, Trond, Frimurer, Thomas Michael, Rist, Ø., Kostenis, E., Högberg, T., Receveur, J. & Grimstrup, M., 2005, Patent No. WO 2005/115382 A1

    Research output: Patent

  27. Published

    CRISPR-engineered human brown-like adipocytes prevent diet-induced obesity and ameliorate metabolic syndrome in mice

    Wang, C., Lundh, M., Fu, A., Kriszt, R., Huang, T. L., Lynes, M. D., Leiria, L. O., Shamsi, F., Darcy, J., Greenwood, B. P., Narain, N. R., Tolstikov, V., Smith, K. L., Emanuelli, Brice, Chang, Y., Hagen, S., Danial, N. N., Kiebish, M. A. & Tseng, Y., 2020, In: Science Translational Medicine. 12, 558, 15 p., eaaz8664.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    COVID-19 editorial: mechanistic links and therapeutic challenges for metabolic diseases one year into the COVID-19 pandemic

    Tessier, C. M., Kokkinos, A., Mingrone, G., Koliaki, C., Zierath, Juleen R & Mantzoros, C. S., 2021, In: Metabolism. 119, 154769.

    Research output: Contribution to journal › Editorial › Research

  29. Published

    CCK-1 and CCK-2 receptor agonism do not stimulate GLP-1 and neurotensin secretion in the isolated perfused rat small intestine or GLP-1 and PYY secretion in the rat colon

    Modvig, Ida Marie, Christiansen, Charlotte Bayer, Rehfeld, Jens Frederik, Holst, Jens Juul & Veedfald, Simon, 2020, In: Physiological Reports. 8, 2, 8 p., 14352.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    CB1 and GLP-1 Receptors Cross Talk Provides New Therapies for Obesity

    Zizzari, P., He, R., Falk, S., Bellocchio, L., Allard, C., Clark, S., Lesté-Lasserre, T., Marsicano, G., Clemmensen, Christoffer, Perez-Tilve, D., Finan, B., Cota, D. & Quarta, C., 2021, In: Diabetes. 70, 2, p. 415-422 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    CAGEfightR: Cap Analysis of Gene Expression (CAGE) in R/Bioconductor

    Thodberg, Malte, Thieffry, A., Vitting-Seerup, K., Andersson, Robin & Sandelin, Albin Gustav, Apr 2018

    Research output: Other contribution › Research

  32. Published

    C4.4A gene ablation is compatible with normal epidermal development and causes modest overt phenotypes

    Kriegbaum, M. C., Jacobsen, B., Fuchtbauer, A., Hansen, Gert Helge, Christensen, I. J., Friis, Carsten, Persson, M., Engelholm, Lars Henning, Madsen, A. N., Di Meo, I., Lund, I. K., Holst, Birgitte, Kjær, Andreas, Laerum, O. D., Fuchtbauer, E. & Ploug, Michael, 12 May 2016, In: Scientific Reports. 6, 25833.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    C-reactive protein levels in relation to various features of non-alcoholic fatty liver disease among obese patients

    Zimmermann, E., Anty, R., Tordjman, J., Verrijken, A., Gual, P., Tran, A., Iannelli, A., Gugenheim, J., Bedossa, P., Francque, S., Le Marchand-Brustel, Y., Clement, K., Van Gaal, L., Sørensen, Thorkild I.A. & Jess, T., 2011, In: Journal of Hepatology. 55, 3, p. 660-5 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    C-reactive protein and cancer

    Allin, K. H., 2011, Faculty of Health Sciences, University of Copenhagen.

    Research output: Book/Report › Ph.D. thesis

  35. Published

    C-peptide increases Na,K-ATPase expression via PKC- and MAP kinase-dependent activation of transcription factor ZEB in human renal tubular cells

    Galuska, D., Pirkmajer, S., Barrès, Romain, Ekberg, K., Wahren, J. & Chibalin, A. V., 2011, In: P L o S One. 6, 12, p. e28294

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    C-cell hyperplasia accompanying thyroid diseases other than medullary carcinoma: an immunocytochemical study by means of antibodies to calcitonin and somatostatin

    Scopsi, L., di Palma, S., Ferrari, C., Holst, Jens Juul & Rehfeld, J. F., 1991, In: Modern Pathology. Vol 4, no.3, p. 297-304

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Butyrate producing colonic Clostridiales metabolise human milk oligosaccharides and cross feed on mucin via conserved pathways

    Pichler, M. J., Yamada, C., Shuoker, B., Alvarez Silva, Maria Camila, Gotoh, A., Leth, M. L., Schoof, E., Katoh, T., Sakanaka, M., Katayama, T., Jin, C., Karlsson, N. G., Arumugam, Mani, Fushinobu, S. & Abou Hachem, M., 2020, In: Nature Communications. 11, 15 p., 3285.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Butyrate inhibits IL-1β-induced inflammatory gene expression by suppression of NF-κB activity in pancreatic beta cells

    Pedersen, Signe Schultz, Prause, Michala Cecilie Burstein, Williams, K., Barrès, Romain & Billestrup, Nils, 2022, In: Journal of Biological Chemistry. 298, 9, 14 p., 102312.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Butyrate functions as a histone deacetylase inhibitor to protect pancreatic beta cells from IL-1β-induced dysfunction

    Pedersen, Signe Schultz, Ingerslev, Lars Roed, Olsen, M., Prause, Michala Cecilie Burstein & Billestrup, Nils, 2024, In: FEBS Journal. 291, 3, p. 566-583

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Butyrate and hexanoate-enriched triglycerides increase postprandrial systemic butyrate and hexanoate in men with overweight/obesity: A double-blind placebo-controlled randomized crossover trial

    van Deuren, T., Smolders, L., Hartog, A., Bouwman, F. G., Holst, Jens Juul, Venema, K., Blaak, E. E. & Canfora, E. E., 2023, In: Frontiers in Nutrition. 9, 19 p., 1066950.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Building Bridges through Scientific Conferences

    Zierath, Juleen R, 17 Nov 2016, In: Cell. 167, 5, p. 1155-1158 4 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  42. Published

    Brugada Syndrome-Associated Genetic Loci Are Associated With J-Point Elevation and an Increased Risk of Cardiac Arrest

    Andreasen, Laura Korsholm, Ghouse, J., Skov, M. W., Have, C. T., Ahlberg, G., Rasmussen, P. V., Linneberg, Allan René, Pedersen, Oluf Borbye, Platonov, P. G., Haunsø, Stig, Svendsen, Jesper Hastrup, Hansen, Torben, Kanters, Jørgen K. & Olesen, Morten Steen Salling, 2018, In: Frontiers in Physiology. 9, p. 1-9 894.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Browning of human adipocytes requires KLF11 and reprogramming of PPARγ superenhancers

    Loft, A., Forss, I., Siersbæk, M. S., Schmidt, S. F., Larsen, A. B., Madsen, J. G. S., Pisani, D. F., Nielsen, R., Aagaard, M. M., Mathison, A., Neville, M. J., Urrutia, R., Karpe, F., Amri, E. & Mandrup, S., 2015, In: Genes & Development. 29, p. 7-22 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Brown fat: the biological furnace that could burn away obesity

    Lund, Jens, Peics, J. & Gerhart-Hines, Zach, 2018, In: Biozoom. 20, 3, p. 4-6 3 p.

    Research output: Contribution to journal › Journal article › Research

  45. Published

    Brown Fat AKT2 Is a Cold-Induced Kinase that Stimulates ChREBP-Mediated De Novo Lipogenesis to Optimize Fuel Storage and Thermogenesis

    Sanchez-Gurmaches, J., Tang, Y., Jespersen, N. Z., Wallace, M., Martinez Calejman, C., Gujja, S., Li, H., Edwards, Y. J. K., Wolfrum, C., Metallo, C. M., Nielsen, S., Schéele, Camilla Charlotte Nielsen & Guertin, D. A., 9 Jan 2018, In: Cell Metabolism. 27, 1, p. 195-209.e6

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Brown Adipose Tissue: A Metabolic Regulator in a Hypothalamic Cross Talk?

    Henningsen, J. B. & Schéele, Camilla Charlotte Nielsen, 2021, In: Annual Review of Physiology. 83, p. 279-301 23 p.

    Research output: Contribution to journal › Review › Research › peer-review

  47. Published

    Brown Adipose Crosstalk in Tissue Plasticity and Human Metabolism

    Schéele, Camilla Charlotte Nielsen & Wolfrum, C., 2020, In: Endocrine Reviews. 41, 1, p. 53-65

    Research output: Contribution to journal › Review › Research › peer-review

  48. Published

    Breastfeeding duration in infancy and adult risks of type 2 diabetes in a high-income country

    Bjerregaard, L. G., Pedersen, D. C., Mortensen, Erik Lykke, Sørensen, Thorkild I.A. & Baker, J. L., 2019, In: Maternal and Child Nutrition. 15, 4, 9 p., e12869.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Breastfeeding and later maternal risk of hypertension and cardiovascular disease - The role of overall and abdominal obesity

    Kirkegaard, H., Bliddal, M., Stovring, H., Rasmussen, K. M., Gunderson, E. P., Køber, Lars Valeur, Sørensen, Thorkild I.A. & Nohr, E. A., 2018, In: Preventive Medicine. 114, p. 140-148 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Breastfeeding and complementary feeding in relation to body mass index and overweight at ages 7 and 11 y: A path analysis within the Danish National Birth Cohort

    Morgen, C. S., Ängquist, Lars, Baker, J. L., Nybo Andersen, Anne-Marie, Sørensen, Thorkild I.A. & Michaelsen, Kim F., 2018, In: American Journal of Clinical Nutrition. 107, 3, p. 313-322 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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