Novo Nordisk Foundation Center for Basic Metabolic Research

  1. Published

    The effect of referral for cardiac rehabilitation on survival following acute myocardial infarction: a comparison survival in two cohorts collected in 1995 and 2003

    Lewinter, C., Bland, J. M., Crouch, S., Doherty, P., Lewin, R. J., Køber, Lars Valeur, Hall, A. S. & Gale, C. P., Feb 2014, In: European Journal of Preventive Cardiology. 21, 2, p. 163-171 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    The effect of preceding glucose decline rate on low-dose glucagon efficacy in individuals with type 1 diabetes: A randomized crossover trial

    Laugesen, C., Schmidt, S., Holst, Jens Juul, Nørgaard, Kirsten & Ranjan, A. G., 2021, In: Diabetes, Obesity and Metabolism. 23, 4, p. 1057-1062 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    The effect of obesity on early fetal growth and pregnancy duration: a cohort study

    Thagaard, I. N., Krebs, Lone, Holm, Jens-Christian, Christiansen, M., Møller, H., Lange, Theis & Larsen, T., 4 Aug 2018, In: Journal of Maternal - Fetal & Neonatal Medicine. 31, 22, p. 2941-2946 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    The effect of metformin versus placebo in combination with insulin analogues on bone mineral density and trabecular bone score in patients with type 2 diabetes mellitus: a randomized placebo-controlled trial

    Nordklint, A. K., Almdal, Thomas Peter, Vestergaard, P., Lundby-Christensen, L., Boesgaard, T. W., Breum, Leif, Gade-Rasmussen, B., Sneppen, S. B., Gluud, C., Hemmingsen, B., Jensen, T., Krarup, T., Madsbad, Sten, Mathiesen, Elisabeth, Perrild, Hans, Tarnow, L., Thorsteinsson, B., drb459, drb459, Lund, S. S. & Eiken, P., 2018, In: Osteoporosis International. 29, 11, p. 2517-2526

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    The effect of metformin on a healthy human gut microbiota

    Nielsen, T., Bryrup, T., Thomsen, C. W., Hansen, T. H., Kern, T., Allin, K. H., Jørgensen, N. R., drb459, drb459, Hansen, T. & Pedersen, Oluf Borbye, 2017, In: Diabetologia. 60, Suppl. 1, p. S113 1 p., 241.

    Research output: Contribution to journalConference abstract in journalResearch

  6. Published

    The effect of melatonin on incretin hormones: results from experimental and randomized clinical studies

    Lauritzen, E. S., Støy, J., Bæch-Laursen, C., Grarup, Niels, Jessen, N., Hansen, Torben, Møller, N., Hartmann, Bolette, Holst, Jens Juul & Kampmann, U., 2021, In: Journal of Clinical Endocrinology and Metabolism. 106, 12, p. e5109-e5123 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    The effect of long-term taurine supplementation and fructose feeding on glucose and lipid homeostasis in Wistar rats

    Larsen, L. H., Orstrup, L. K. H., Hansen, S. H., Grunnet, N., Quistorff, B. & Mortensen, Ole Hartvig, 2013, In: Advances in Experimental Medicine and Biology. 776, p. 39-50 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    The effect of intensive insulin therapy on the insulin-regulatable glucose transporter (GLUT4) expression in skeletal muscle in type 1 diabetes

    Andersen, P. H., drb459, drb459, Lund, S., Vedel, P., Junker, S., Kahn, B. B. & Pedersen, Oluf Borbye, Oct 1993, In: Diabetic Medicine. 10, 8, p. 699-706 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    The effect of impaired glucose metabolism on weight loss in multidisciplinary childhood obesity treatment

    Kloppenborg, J. T., Gamborg, Michael Orland, Fonvig, Cilius Esmann, Nielsen, T. R. H., Pedersen, Oluf Borbye, Johannesen, Jesper, Hansen, Torben & Holm, Jens-Christian, 2018, In: Pediatric Diabetes. 19, 3, p. 366-374 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    The effect of gluten in adolescents and young adults with gastrointestinal symptoms: A blinded randomised cross-over trial

    Crawley, C., Savino, N., Halby, C., Sander, S. D., Nybo Andersen, Anne-Marie, Arumugam, Mani, Murray, J., Christensen, R. & Husby, S., 2022, In: Alimentary Pharmacology and Therapeutics, Supplement. 55, 9, p. 1116-1127 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    The effect of glucose on the plasma concentration of somatostatin during caloric deficiency in man

    Øktedalen, O., Opstad, P. K. & Holst, Jens Juul, 1993, In: Scandinavian Journal of Gastroenterology. 28, p. 652-656

    Research output: Contribution to journalJournal articleResearch

  12. Published

    The effect of glucagon-like peptide 1 on cardiovascular risk

    Sivertsen, J., Rosenmeier, J., Holst, Jens Juul & Vilsbøll, T., Apr 2012, In: Nature Reviews Cardiology. 9, 4, p. 209-22 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    The effect of ferritin-guided iron supplementation among Danish female first-time blood donors

    Drechsler, L. Ø., Boldsen, J. K., Hindhede, L., Aagaard, B., Harritshøj, Lene Holm, Mikkelsen, Christina, Brodersen, T., Brøns, N., Schwinn, M., Hjalgrim, Henrik, Rostgaard, K., Topholm Bruun, M., Ostrowski, Sisse Rye, Pedersen, Ole Birger Vesterager, Mikkelsen, S. & Erikstrup, C., 2023, In: Transfusion. 63, 9, p. 1710-1718 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    The effect of exogenous glucagon on circulating amino acids in individuals with and without type 2 diabetes and obesity

    Grøndahl, M. F. G., Bagger, J. I., Suppli, M. P., van Hall, Gerrit, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Vilsbøll, Tina, Christensen, Mikkel Bring, Lund, A. B. & Knop, Filip Krag, 2024, In: Endocrine Connections. 13, 3, 7 p., e230516.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    The effect of drinking water pH on the human gut microbiota and glucose regulation: results of a randomized controlled cross-over intervention

    Hansen, T. H., Thomassen, M. T., Madsen, M. L., Kern, T., Bak, Emilie Glad, Kashani, A., Allin, K. H., Hansen, Torben & Pedersen, Oluf Borbye, 2018, In: Scientific Reports. 8, 12 p., 16626.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    The effect of dietary fish oil in addition to lifestyle counselling on lipid oxidation and body composition in slightly overweight teenage boys

    Pedersen, M. H., Mølgaard, Christian, Hellgren, L., Matthiessen, J., Holst, Jens Juul & Lauritzen, Lotte, 2011, In: Journal of Nutrition and Metabolism. 2011, 348368, 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    The effect of dietary carbohydrate restriction beyond weight loss on health-related quality of life and cognition

    Jensen, N. J., Wodschow, H. Z., fbg982, fbg982, Samkani, A., Astrup, A., Frystyk, J., Hartmann, Bolette, Holst, Jens Juul, Larsen, T. M., Madsbad, Sten, Magkos, Faidon, Miskowiak, Kamilla, Rungby, Jørgen, Haugaard, Steen Bendix & Thomsen, M. N., 2021, In: Diabetologia. 64, SUPPL 1, p. 62-63 114.

    Research output: Contribution to journalConference abstract in journalResearch

  18. Published

    The effect of diaries written by relatives for intensive care patients on posttraumatic stress (DRIP study): protocol for a randomized controlled trial and mixed methods study

    Nielsen, A. H., Angel, S., Egerod, Ingrid Eugenie & Hansen, Torben, 2018, In: BMC Nursing. 17, p. 1-10 10 p., 37.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    The effect of diabetes and the diabetogenic TBC1D4 p.Arg684ter variant on kidney function in Inuit in Greenland

    Overvad, M., Díaz, L. J., Bjerregaard, P., Pedersen, M. L., Larsen, C. V. L., Grarup, Niels, Hansen, Torben, Rossing, Peter & Jørgensen, M. E., 2023, In: International Journal of Circumpolar Health. 82, 8 p., 2191406.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    The effect of diabetes and the common diabetogenic TBC1D4 p.Arg684Ter variant on cardiovascular risk in Inuit in Greenland

    Overvad, M., Diaz, L. J., Bjerregaard, P., Pedersen, M. L., Larsen, C. V. L., Senftleber, N., Grarup, Niels, Hansen, Torben & Jørgensen, M. E., 2020, In: Scientific Reports. 10, 9 p., 22081.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    The effect of curcumin on hepatic fat content in individuals with obesity

    Hellmann, P. H., Bagger, J. I., Carlander, K. R., Forman, Julie Lyng, Chabanova, E., Svenningsen, J. S., Holst, Jens Juul, Gillum, M. P., Vilsbøll, Tina & Knop, Filip Krag, 2022, In: Diabetes, Obesity and Metabolism. 24, 11, p. 2192-2202 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    The effect of casein, hydrolyzed casein, and whey proteins on urinary and postprandial plasma metabolites in overweight and moderately obese human subjects

    Schmedes, M. S., Bendtsen, L. Q., Gomes, S., Liaset, B., Holst, Jens Juul, Ritz, C., Reitelseder, S., Sjödin, Anders Mikael, Astrup, A., Young, J. F., Sundekilde, U. K. & Bertram, H. C., 2018, In: Journal of the Science of Food and Agriculture. 98, 15, p. 5598-5605 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    The effect of an extreme and prolonged population bottleneck on patterns of deleterious variation: insights from the Greenlandic Inuit

    Pedersen, C. T., Lohmueller, K. E., Grarup, Niels, Bjerregaard, P., Hansen, Torben, Siegismund, Hans Redlef, Moltke, Ida & Albrechtsen, Anders, Feb 2017, In: Genetics. 205, 2, p. 787-801 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    The effect of acute intragastric vs. intravenous alcohol administration on inflammation markers, blood lipids and gallbladder motility in healthy men

    Lanng, A. R., Gasbjerg, Lærke Smidt, Bergmann, N. C., Gillum, M. P., Rehfeld, Jens Frederik, Helsted, M. M., Møller, H. J., Grønbæk, H., Vilsbøll, Tina & Knop, Filip Krag, 2020, In: Alcohol. 87, p. 29-37 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    The effect of acute dual SGLT1/SGLT2 inhibition on incretin release and glucose metabolism after gastric bypass surgery

    Martinussen, C., Veedfald, Simon, Dirksen, Carsten Moro, Bojsen-Møller, K. N., Svane, M. S., Albrechtsen, Nicolai Jacob Wewer, van Hall, Gerrit, Kristiansen, V. B., Fenger, M., Holst, Jens Juul & Madsbad, Sten, 2020, In: American Journal of Physiology: Endocrinology and Metabolism. 318, 6, p. E956-E964 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    The effect of a very low calorie diet on insulin sensitivity, beta cell function, insulin clearance, incretin hormone secretion, androgen levels and body composition in obese young women

    Svendsen, P. F., Jensen, F. K., Holst, Jens Juul, Haugaard, Steen Bendix, Nilas, L. & Madsbad, Sten, Sep 2012, In: Scandinavian Journal of Clinical & Laboratory Investigation. 72, 5, p. 410-9 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    The effect of a subcutaneous infusion of GLP-1, OXM and PYY on Energy intake and Expenditure in Obese volunteers

    Tan, T., Behary, P., Tharakan, G., Minnion, J., Al-Najim, W., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul & Bloom, S. R., 1 Jul 2017, In: The Journal of clinical endocrinology and metabolism. 102, 7, p. 2364-2372 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published
  29. Published

    The effect of Roux-en-Y gastric bypass surgery on energy expenditure and appetite: a randomized human study including “pair fed” control subjects

    Schmidt, J. B., Gregersen, N. T., Pedersen, S., Nielsen, M. S., Nielsen, L. V., Holst, Jens Juul, Hansen, D. L., Dorm, D. W., Madsbad, Sten, Clausen, T. R. C., Ritz, C., Astrup, A. & Sjödin, Anders Mikael, 2013, In: Obesity Facts. 6, suppl. 1, p. 28 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  30. Published

    The effect of Glucagon-Like Peptide-2 on mesenteric blood flow and cardiac parameters in end-jejunostomy short bowel patients

    Bremholm, L., Hornum, Mads, Andersen, U. B., Hartmann, Bolette, Holst, Jens Juul & Jeppesen, Palle Bekker, 2011, In: Regulatory Peptides. 168, 1-3, p. 32-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    The effect of GWAS identified BMI loci on changes in body weight among middle-aged danes during a five year period

    Sandholt, C. H., Allin, K. H., Toft, U., Borglykke, A., Ribel-Madsen, R., Sparsø, T. H., Justesen, Johanne Marie, Harder, M. N., Jørgensen, T., Hansen, Torben & Pedersen, Oluf Borbye, 26 Jun 2013, In: Obesity. 22, 3, p. 901-908 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    The effect of FOXA2 rs1209523 on glucose-related phenotypes and risk of type 2 diabetes in Danish individuals

    Banasik, Karina, Hollensted, M., Andersson, E., Sparsø, T., Sandbaek, A., Lauritzen, T., Jørgensen, T., Witte, D. R., Pedersen, Oluf Borbye & Hansen, Torben, 2012, In: B M C Medical Genetics. 13, p. 10

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    The effect of DPP-4-protected GLP-1 (7-36) on coronary microvascular function in obese adults

    Nilsson, M., Bové, K. B., Suhrs, E., Hermann, T., Madsbad, Sten, Holst, Jens Juul, Prescott, Eva & Zander, M., Mar 2019, In: IJC Heart and Vasculature. 22, p. 139-144

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    The effect of DPP-4 protected GLP-1 (7-36) on coronary microcirculation in obese adults

    Nilsson, M., Bove, K., Suhrs, E., Hermann, T., Madsbad, Sten, Holst, Jens Juul, Prescott, Eva & Zander, M., 2018, In: Diabetologia. 61, S1, p. S354-S355 729.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  35. Published

    The effect of 6-day subcutaneous glucose-dependent insulinotropic polypeptide infusion on time in glycaemic range in patients with type 1 diabetes: a randomised, double-blind, placebo-controlled crossover trial

    Heimbürger, S. M. N., Hoe, B., Nielsen, C. N., Bergmann, N. C., Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina, Dejgaard, T. F., Christensen, Mikkel Bring & Knop, Filip Krag, 2021, In: Diabetologia. 64, p. 2425-2431

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    The diurnal variation of bone formation is attenuated in adult patients with type 2 diabetes

    Hygum, K., Starup-Linde, J., Harslor, T., Jørgensen, Niklas Rye, Hartmann, Bolette, Holst, Jens Juul & Langdahl, B. L., 2019, In: European Journal of Endocrinology. 181, 3, p. 221-231

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    The dissociation of tumor-induced weight loss from hypoglycemia in a transplantable pluripotent rat islet tumor results in the segregation of stable alpha- and beta-cell tumor phenotypes

    Madsen, O. D., Karlsen, C., Nielsen, E., Lund, K., Kofod, H., Welinder, B., Rehfeld, Jens Frederik, Larsson, L. I., Steiner, D. F. & Holst, Jens Juul, Nov 1993, In: Endocrinology. 133, 5, p. 2022-30 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    The dissociation of tumor-induced weight loss from hypoglycemia in a transplantable pluripotent rat islet tumor results in the segregation of stable *Ga- and *Gb-cell tumor phenotypes

    Madsen, O. D., Karlsen, G., Nielsen, E., Lund, K., Kofod, H., Welinder, B., Rehfeld, J. F., Larsson, L., Steiner, D. F., Holst, Jens Juul & Michelsen, B. K., 1993, In: Endokrinologiya. vol. 133, no. 5, p. 2022-2030

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    The disruption of mitochondrial axonal transport is an early event in neuroinflammation

    Errea, O., Moreno, B., Gonzalez-Franquesa, A., Garcia-Roves, P. M. & Villoslada, P., 28 Aug 2015, In: Journal of Neuroinflammation. 12, p. 152

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    The differing impact of chloroquine and pyrimethamine/sulfadoxine upon the infectivity of malaria species to the mosquito vector

    Høgh, Birthe, Gamage-Mendis, A., Butcher, G. A., Thompson, R., Begtrup, K., Mendis, C., Enosse, S. M., Dgedge, M., Barreto, J., Eling, W. & Sinden, R. E., Feb 1998, In: American Journal of Tropical Medicine and Hygiene. 58, 2, p. 176-82 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    The dietary regulation of LEAP2 depends on meal composition in mice

    Gradel, Anna Katrina Jógvansdóttir, Holm, Stephanie Kjærulff, Byberg, Sarah, Merkestein, M., Hogendorf, W. F. J., Lund, M. L., Buijink, June D.A., Damgaard, J., Lykkesfeldt, Jens & Holst, Birgitte, 2023, In: FASEB Journal. 37, 6, 21 p., 22923.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    The diabetogenic VPS13C/C2CD4A/C2CD4B rs7172432 variant impairs glucose-stimulated insulin response in 5,722 non-diabetic Danish individuals

    Grarup, Niels, Overvad, M., Sparsø, T., Witte, D. R., Pisinger, C., Jørgensen, T., Yamauchi, T., Hara, K., Maeda, S., Kadowaki, T., Hansen, T. & Pedersen, Oluf Borbye, 2011, In: Diabetologica. 54, 4, p. 789-94 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    The developmental neurogenic niche of the Entorhinal cortex revealed by single-cell transcriptomics.

    Bergmann, T. B., Liu, Y., Lee, J., Peralvo Vidal, Juan Miguel, Mori, Yuki, Seemann, Ernst Stefan, Pihl, M., Thomsen, Preben Dybdahl, Hyttel, P., witter, M., Gorodkin, Jan, Hall, Vanessa Jane & Pers, Tune H, 2018.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  44. Published

    The developing infant gut microbiome: A strain-level view

    Enav, H., Bäckhed, F. & Ley, R. E., 2022, In: Cell Host and Microbe. 30, 5, p. 627-638 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

  45. Published

    The developing airway and gut microbiota in early life is influenced by age of older siblings

    Christensen, E. D., Hjelmsø, M. H., Thorsen, Jonathan Jan Ilve, Shah, S., Redgwell, T., Poulsen, Christina Egeø, Trivedi, Urvish, Russel, J., Gupta, S., Chawes, Bo Lund Krogsgaard, Bønnelykke, Klaus, Sørensen, Søren Johannes, Rasmussen, Morten Arendt, Bisgaard, H. & Stokholm, Jakob, 2022, In: Microbiome. 10, 15 p., 106.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    The developing Entorhinal cortex - a cellular map

    Bergmann, T. B., Liu, Y., Lee, J., Pfisterer, U. G., Handfield, L., Asenjo Martinez, A., Seemann, Ernst Stefan, Witter, M., Khodosevich, Konstantin, Gorodkin, Jan, Hemberg, M., Pers, Tune H & Hall, Vanessa Jane, 25 Nov 2019. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceCommunication

  47. Published

    The developing Entorhinal Cortex – a cellular map

    Bergmann, T. B., Liu, Y., Lee, J., Pfisterer, U. G., Asenjo Martinez, A., Seemann, Ernst Stefan, Pihl, M., Thomsen, Preben Dybdahl, Hyttel, P., witter, M., Khodosevich, Konstantin, Gorodkin, Jan, Pers, Tune H & Hall, Vanessa Jane, 2019.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  48. Published

    The derived allele of a novel intergenic variant at chromosome 11 associates with lower body mass index and a favorable metabolic phenotype in Greenlanders

    Andersen, M. K., Jørsboe, E., Skotte, L., Hanghøj, K., Sandholt, C. H., Moltke, I., Grarup, N., Kern, T., Mahendran, Y., Søborg, B., Bjerregaard, P., Larsen, C. V. L., Dahl-Petersen, I. K., Tiwari, H. K., Feenstra, B., Koch, A., Wiener, H. W., Hopkins, S. E., Pedersen, O., Melbye, M. & 4 others, Boyer, B. B., Jørgensen, M. E., Albrechtsen, Anders & Hansen, Torben, 2020, In: PLOS Genetics. 16, 1, 17 p., e1008544.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    The contribution of functional HNF1A variants and polygenic susceptibility to risk of type 2 diabetes in ancestrally diverse populations

    Stalbow, L. A., Preuss, M. H., Smit, Roelof Adriaan Johan, Chami, N., Bjørkhaug, L., Aukrust, I., Gloyn, A. L. & Loos, Ruth, 2023, In: Diabetologia. 66, p. 116-126 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    The complement system is differently regulated in white and brown adipocytes

    Justesen, L., Bayarri-Olmos, R., Schéele, Camilla Charlotte Nielsen & Garred, Peter, 2018, In: Molecular Immunology. 102, p. 170 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

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