Novo Nordisk Foundation Center for Basic Metabolic Research

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  1. 2023
  2. Published

    Effects of glepaglutide, a long-acting glucagon-like peptide-2 analog, on intestinal morphology and perfusion in patients with short bowel syndrome: Findings from a randomized phase 2 trial

    Naimi, R. M., Hvistendahl, M. K., Poulsen, Steen Seier, Kissow, Hannelouise, Pedersen, Jens, Nerup, N. A., Ambrus, R., Achiam, Michael Patrick, Svendsen, Lars Bo & Jeppesen, Palle Bekker, 2023, In: Journal of Parenteral and Enteral Nutrition. 47, 1, p. 140-150

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Effects of levothyroxine substitution therapy on hunger and food intake in individuals with hypothyroidism

    Medici, B. R., Nygaard, Birte, la Cour, J. L., Krakauer, M., Brønden, Andreas, Sonne, M. P., Holst, Jens Juul, Rehfeld, Jens Frederik, Vilsbøll, Tina, Faber, J. & Knop, Filip Krag, 2023, In: Endocrine Connections. 12, 10, 14 p., e230314.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Effects of topical corticosteroid vs. tacrolimus on insulin sensitivity and bone homeostasis in adults with atopic dermatitis - a randomized controlled study

    Gether, L., Storgaard, H., Kezic, S., Jakasa, I., Hartmann, Bolette, Skov-Jeppesen, Kirsa, Holst, Jens Juul, Pedersen, A. J., Forman, Julie Lyng, van Hall, Gerrit, Sørensen, O. E., Skov, Lone, Røpke, Mads Almose, Knop, Filip Krag & Thyssen, Jacob Pontoppidan, 2023, In: Allergy. 78, 7, p. 1964-1979 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Emergence of the obesity epidemic preceding the presumed obesogenic transformation of the society

    Pedersen, M. M., Ekstrøm, Claus Thorn & Sørensen, Thorkild I.A., 2023, In: Science Advances. 9, 37, 7 p., eadg6237.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Endogenous glucagon-like peptide (GLP)-1 as alternative for GLP-1 receptor agonists: Could this work and how?

    Smits, Mark & Holst, Jens Juul, 2023, In: Diabetes/Metabolism Research and Reviews. 39, 8, 17 p., e3699.

    Research output: Contribution to journal › Review › Research › peer-review

  7. Published

    Endogenous incretin levels and risk of first incident cancer: a prospective cohort study

    Jujic, A., Godina, C., Belting, M., Melander, O., Holst, Jens Juul, Ahlqvist, E., Gomez, M. F., Nilsson, P. M., Jernstrom, H. & Magnusson, M., 2023, In: Scientific Reports. 13, 1, 11 p., 382.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Endosomal egress and intercellular transmission of hepatic ApoE-containing lipoproteins and its exploitation by the hepatitis C virus

    Pham, M., Lee, J., Ritter, C., Thielemann, Roman, Meyer, J., Haselmann, U., Funaya, C., Laketa, V., Rohr, K. & Bartenschlager, R., 2023, In: PLoS Pathogens. 19, 7, 40 p., e1011052.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Environmental exposures are important for type 2 diabetes pathophysiology in sub-Saharan African populations

    Christensen, Dirk Lund, Hjort, Line, Mpagama, S. G. & Ramaiya, K. L., 2023, In: Diabetologia. 66, p. 777–779 3 p.

    Research output: Contribution to journal › Letter › Research

  10. Published

    Estimation of Life's Essential 8 Score with Incomplete Data of Individual Metrics

    Zheng, Y., Huang, T., Guasch Ferre, Marta, Hart, J., Laden, F., Chavarro, J., Rimm, E., Coull, B. & Hu, H., 2023, In: Frontiers in Cardiovascular Medicine. 10, 11 p., 1216693.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation

    Budu-Aggrey, A., Kilanowski, A., Sobczyk, M. K., Shringarpure, S. S., Mitchell, R., Reis, K., Reigo, A., Mägi, R., Nelis, M., Tanaka, N., Brumpton, B. M., Thomas, L. F., Sole-Navais, P., Flatley, C., Espuela-Ortiz, A., Herrera-Luis, E., Lominchar, J. V. T., Bork-Jensen, J., Marenholz, I., Arnau-Soler, A. & 112 others, Jeong, A., Fawcett, K. A., Baurecht, H., Rodriguez, E., Alves, A. C., Kumar, A., Sleiman, P. M., Chang, X., Medina-Gomez, C., Hu, C., Xu, C. J., Qi, C., El-Heis, S., Titcombe, P., Antoun, E., Fadista, J., Wang, C. A., Thiering, E., Wu, B., Kress, S., Kothalawala, D. M., Kadalayil, L., Duan, J., Zhang, H., Hadebe, S., Hoffmann, T., Jorgenson, E., Choquet, H., Risch, N., Njølstad, P., Andreassen, O. A., Johansson, S., Almqvist, C., Gong, T., Ullemar, V., Karlsson, R., Magnusson, P. K. E., Szwajda, A., Burchard, E. G., Thyssen, Jacob Pontoppidan, Hansen, Torben, Kårhus, L. L., Dantoft, T. M., Jeanrenaud, A. C. S. N., Ghauri, A., Arnold, A., Homuth, G., Lau, S., Nöthen, M. M., Hübner, N., Imboden, M., Visconti, A., Falchi, M., Bataille, V., Hysi, P., Ballardini, N., Boomsma, D. I., Hottenga, J. J., Müller-Nurasyid, M., Ahluwalia, T. S., Stokholm, J., Chawes, Bo Lund Krogsgaard, Schoos, Ann-Marie Malby, Esplugues, A., Bustamante, M., Raby, B., Arshad, S., German, C., Esko, T., Milani, L. A., Metspalu, A., Terao, C., Abuabara, K., Løset, M., Hveem, K., Jacobsson, B., Pino-Yanes, M., Strachan, D. P., Grarup, Niels, Linneberg, Allan René, Lee, Y. A., Probst-Hensch, N., Weidinger, S., Jarvelin, M. R., Melén, E., Hakonarson, H., Irvine, A. D., Jarvis, D., Nijsten, T., Duijts, L., Vonk, J. M., Koppelmann, G. H., Godfrey, K. M., Barton, S. J., Feenstra, B., Pennell, C. E., Sly, P. D., Holt, P. G., Williams, L. K., Bisgaard, H., Bønnelykke, Klaus, Curtin, J., Simpson, A., Murray, C., Schikowski, T., Bunyavanich, S., Weiss, S. T., Holloway, J. W., Min, J. L., Brown, S. J., Standl, M. & Paternoster, L., 2023, In: Nature Communications. 14, 6172.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Evidence of a causal and modifiable relationship between kidney function and circulating trimethylamine N-oxide

    Andrikopoulos, P., Aron-Wisnewsky, J., Chakaroun, R., Myridakis, A., Forslund, S. K., Nielsen, T., Adriouch, S., Holmes, B., Chilloux, J., Vieira-Silva, S., Falony, G., Salem, J. E., Andreelli, F., Belda, E., Kieswich, J., Chechi, K., Puig-Castellvi, F., Chevalier, M., Le Chatelier, E., Olanipekun, M. T. & 83 others, Hoyles, L., Alves, R., Helft, G., Isnard, R., Køber, Lars Valeur, Coelho, L. P., Rouault, C., Gauguier, D., Goetze, Jens P. , Prifti, E., Froguel, P., Alili, R., Galijatovic, E. A. A., Barthelemy, O., Bastard, J. P., Batisse, J. P., Bel-Lassen, P., Berland, M., Bittar, R., Blottière, H., Bosquet, F., Boubrit, R., Bourron, O., Camus, M., Ciangura, C., Collet, J. P., Dietrich, A., Djebbar, M., Doré, A., pjx571, pjx571, Fezeu, L., Fromentin, S., Pons, N., Graine, M., Grünemann, C., Hartemann, A., Hartmann, Bolette, Hornbak, M., Jaqueminet, S., Jørgensen, Niklas Rye, Julienne, H., Justesen, Johanne Marie, Kammer, J., Karup, N., Kozlowski, R., Kuhn, M., Lejard, V., Letunic, I., Levenez, F., Marko, L., Martinez-Gili, L., Massey, R., Maziers, N., Moitinho-Silva, L., Montalescot, G., Neves, A. L., Le Pavin, L. P., Pousset, F., Rodriguez-Martinez, A., Schmidt, S., Schütz, T., Silva, L., Silvain, J., Svendstrup, M., Swartz, T. D., Vanduyvenboden, T., Verger, E. O., Walther, S., Zucker, J. D., Bäckhed, F., drb459, drb459, Hansen, Torben, Oppert, J. M., Blüher, M., Nielsen, J., Raes, J., Bork, P., Yaqoob, M. M., Stumvoll, M., Pedersen, Oluf Borbye, Ehrlich, S. D., Clément, K. & Dumas, M. E., 2023, In: Nature Communications. 14, 18 p., 5843.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Exercise metabolism and adaptation in skeletal muscle

    Smith, J. A. B., Murach, K. A., Dyar, K. A. & Zierath, Juleen R, 2023, In: Nature Reviews Molecular Cell Biology. 24, p. 607-632

    Research output: Contribution to journal › Review › Research › peer-review

  14. Published

    Exercise-related hypoglycaemia induces QTc-interval prolongation in individuals with type 1 diabetes

    Hagelqvist, P. G., Andersen, A., Maytham, K. B., Andreasen, C. R., Engberg, S., Lindhardt, T. B., Faber, Jens, Holst, Jens Juul, Forman, Julie Lyng, Pedersen-Bjergaard, Ulrik, Knop, Filip Krag & Vilsbøll, Tina, 2023, In: Diabetes, Obesity and Metabolism. 25, 5, p. 1186-1195 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Expanding known viral diversity in the healthy infant gut

    Shah, S. A., Deng, L., Thorsen, J., Pedersen, A. G., Dion, M. B., Castro-Mejía, J. L., Silins, R., Romme, F. O., Sausset, R., Jessen, L. E., Ndela, E. O., Hjelmsø, M., Rasmussen, M. A., Redgwell, T. A., Rodríguez, C. L., Vestergaard, G., Zhang, Y., Chawes, B., Bønnelykke, K., Sørensen, S. J. & 6 others, Bisgaard, H., Enault, F., Stokholm, Jakob, Moineau, S., Petit, M. A. & Nielsen, Dennis Sandris, 2023, In: Nature Microbiology. 8, p. 986–998

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    FK506-Binding Protein 2 Participates in Proinsulin Folding

    Hoefner, C., Bryde, T. H., Pihl, C., Tiedemann, S. N., Bresson, S. E., Hotiana, H. A., Khilji, M. S., Santos, T. D., Puglia, M., Pisano, P., Majewska, M., Durzynska, J., Klindt, K., Klusek, J., Perone, M. J., Bucki, R., Hägglund, P. M., Gourdon, P. E., Gotfryd, K., Urbaniak, E. & 5 others, Borowiak, M., Wierer, M., MacDonald, P. E., Mandrup-Poulsen, Thomas & Marzec, Michal Tomasz, 2023, In: Biomolecules. 13, 1, 20 p., 152.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    FOXO3A-short is a novel regulator of non-oxidative glucose metabolism associated with human longevity

    Santo, E. E., Ribel-Madsen, R., Stroeken, P. J., de Boer, V. C. J., Hansen, N. S., Commandeur, M., Vaag, Allan, Versteeg, R., Paik, J. & Westerhout, E. M., 2023, In: Aging Cell. 22, 3, 13 p., e13763.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Free fatty acid receptor 1 stimulates cAMP production and gut hormone secretion through Gq-mediated activation of adenylate cyclase 2

    Petersen, Jacob Emil, Pedersen, M. H., Dmytriyeva, O., Nellemose, E., Arora, Tulika, Engelstoft, M. S., Asher, W. B., Javitch, J. A., Schwartz, Thue W. & Trauelsen, Mette, 2023, In: Molecular Metabolism. 74, 10 p., 101757.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    From Mausoleum to Living Room. Practicing Metabolic Carpentry in the Museum

    Grünfeld, Martin, Bencard, Adam & Whiteley, Louise, 2023, In: Centaurus. 65, 2, p. 387-416 30 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Full activation of thermogenesis in brown adipocytes requires Basigin action

    Rupar, K., Isidor, Marie Sophie, Argemi Muntadas, Lidia, Agueda Oyarzabal, Marina, Plucinska, Kaja, Brown, E. L., Mattanovich, M., Bossi, Simone, Tozzi, M., Tandio, David, Petersen, P. S. S., Henriksen, T. I., Trošt, K., Hansen, Jacob B., Gerhart-Hines, Zach, Nielsen, S., Moritz, Thomas & Emanuelli, Brice, 2023, In: F E B S Journal. 290, 10, p. 2673-2691

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Functional assay for assessment of agonistic or antagonistic activity of angiotensin AT2 receptor ligands reveals that EMA401 and PD123319 have agonistic properties

    Peluso, A. A., Souza-Silva, I. M., Villela, D. C., Hansen, P. B. L., Hallberg, A., Bader, M., Santos, R., Sumners, C. & Steckelings, U. M., 2023, In: Biochemical Pharmacology. 216, 12 p., 115793.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Fungi and bacteria in the beds of rural and urban infants correlate with later risk of atopic diseases

    Lehtimäki, J., Gupta, S., Hjelmsø, M., Shah, S., Thorsen, Jonathan Jan Ilve, Rasmussen, Morten Arendt, Soverini, M., Li, Xuan Ji, Russel, J., Trivedi, Urvish, Brix, S., Bønnelykke, Klaus, Chawes, Bo Lund Krogsgaard, Bisgaard, H., Sørensen, Søren Johannes & Stokholm, Jakob, 2023, In: Clinical and Experimental Allergy. 53, 12, p. 1268-1278 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    G-Protein-Coupled Receptor 91-Dependent Signalling Does Not Influence Vascular Inflammation and Atherosclerosis in Hyperlipidaemic Mice

    Griepke, S., Trauelsen, Mette, Nilsson, M. D., Hansen, J., Steffensen, L. B., Schwartz, Thue W. & Ketelhuth, D. F. J., 2023, In: Cells. 12, 21, 14 p., 2580.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    GDF15 increases insulin action in the liver and adipose tissue via a β-adrenergic receptor-mediated mechanism

    Sjøberg, K. A., Sigvardsen, Casper Møller, Alvarado-Diaz, A., Andersen, Nicoline Resen, Larance, M., Seeley, R. J., Schjerling, Peter, Knudsen, Jakob Grunnet, Katzilieris Petras, Georgios, Clemmensen, Christoffer, Jørgensen, S. B., De Bock, K. & Richter, Erik A., 2023, In: Cell Metabolism. 35, 8, p. 1327-1340.e5 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    GLP-1 and nicotine combination therapy engages hypothalamic and mesolimbic pathways to reverse obesity

    Falk, S., Petersen, Jonas Odgaard, Svendsen, C. S. A., Leguizamon, Cesar Ramon Romero, Jørgensen, Søren Heide, Krauth, Nathalie, Ludwig, M. Q., Jørgensen, Kathrine Lundø, Roostalu, U., Hjort-Gregersen, G. S., Nielsen, D. A. G., Ejdrup, Aske Lykke, Pers, Tune H, Dmytriyeva, O., Hecksher-Soerensen, J., Gether, Ulrik, Kohlmeier, Kristi Anne & Clemmensen, Christoffer, 2023, In: Cell Reports. 42, 5, 18 p., 112466.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    GWAS of random glucose in 476,326 individuals provide insights into diabetes pathophysiology, complications and treatment stratification

    Lagou, V., Jiang, L., Ulrich, A., Zudina, L., González, K. S. G., Balkhiyarova, Z., Faggian, A., Maina, J. G., Chen, S., Todorov, P. V., Sharapov, S., David, A., Marullo, L., Mägi, R., Rujan, R. M., Ahlqvist, E., Thorleifsson, G., Gao, Η., Εvangelou, Ε., Benyamin, B. & 78 others, Scott, R. A., Isaacs, A., Zhao, J. H., Willems, S. M., Johnson, T., Gieger, C., Grallert, H., Meisinger, C., Müller-Nurasyid, M., Strawbridge, R. J., Goel, A., Rybin, D., Albrecht, E., Jackson, A. U., Stringham, H. M., Corrêa, I. R., Farber-Eger, E., Steinthorsdottir, V., Uitterlinden, A. G., Munroe, P. B., Brown, M. J., Schmidberger, J., Holmen, O., Thorand, B., Hveem, K., Wilsgaard, T., Mohlke, K. L., Wang, Z., den Hoed, M., Shmeliov, A., den Hoed, M., Loos, Ruth, Kratzer, W., Haenle, M., Koenig, W., Boehm, B. O., Tan, T. M., Tomas, A., Salem, V., Barroso, I., Tuomilehto, J., Boehnke, M., Florez, J. C., Hamsten, A., Watkins, H., Njølstad, I., Wichmann, H. E., Caulfield, M. J., Khaw, K. T., van Duijn, C. M., Hofman, A., Wareham, N. J., Langenberg, C., Whitfield, J. B., Martin, N. G., Montgomery, G., Scapoli, C., Tzoulaki, I., Elliott, P., Thorsteinsdottir, U., Stefansson, K., Brittain, E. L., McCarthy, M. I., Froguel, P., Sexton, P. M., Wootten, D., Groop, L., Dupuis, J., Meigs, J. B., Deganutti, G., Demirkan, A., Pers, Tune H, Reynolds, C. A., Aulchenko, Y. S., Kaakinen, M. A., Jones, B., Prokopenko, I. & van Duijn, C. M., 2023, In: Nature Genetics. 55, 9, p. 1448-1461 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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