Novo Nordisk Foundation Center for Basic Metabolic Research

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  1. 2023
  2. Published

    Genetic predisposition to macronutrient preference and workplace food choices

    Merino, Jordi, Dashti, H. S., Levy, D. E., Del Rocío Sevilla-González, M., Hivert, M. F., Porneala, B. C., Saxena, R. & Thorndike, A. N., 2023, In: Molecular Psychiatry. 28, 9, p. 2606–2611

    Research output: Contribution to journal › Review › Research › peer-review

  3. Published

    Genetic variants associated with syncope implicate neural and autonomic processes

    Aegisdottir, H. M., Thorolfsdottir, R. B., Sveinbjornsson, G., Stefansson, O. A., Gunnarsson, B., Tragante, V., Thorleifsson, G., Stefansdottir, L., Thorgeirsson, T. E., Ferkingstad, E., Sulem, P., Norddahl, G., Rutsdottir, G., Banasik, K., Christensen, A. H., Mikkelsen, C., Pedersen, O. B., Brunak, S., Bruun, M. T., Erikstrup, C. & 26 others, Jacobsen, R. L., Nielsen, K. R., Sorensen, E., Frigge, M. L., Hjorleifsson, K. E., Ivarsdottir, E., Helgadottir, A., Gretarsdottir, S., Steinthorsdottir, V., Oddsson, A., Eggertsson, H. P., Halldorsson, G. H., Jones, D. A., Anderson, J. L., Knowlton, K. U., Nadauld, L. D., DBDS Genomic Consortium, D. B. D. S. G. C., Haraldsson, M., Thorgeirsson, G., Bundgård, Henning, Arnar, D. O., Thorsteinsdottir, U., Gudbjartsson, D. F., Ostrowsk, S. R., Holm, H. & Stefansson, K., 2023, In: European Heart Journal. 44, 12, p. 1070–1080 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Genetics of Plasma Bilirubin and Associations between Bilirubin and Cardiometabolic Risk Profiles in Danish Children and Adolescents

    Ullah, A., Stankevic, Evelina, Holm, L. A., Stinson, Sara, Juel, H. B., Fonvig, Cilius Esmann, Lund, M. A. V., Trier, C., pjx571, pjx571, Ängquist, Lars, Jonsson, Anna Elisabet, Pedersen, Oluf Borbye, Grarup, Niels, Holm, Jens-Christian & Hansen, Torben, 2023, In: Antioxidants. 12, 8, 1613.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Genetics of metabolic traits in Greenlanders

    Thuesen, Anne Cathrine Baun, Lepola, Mette Andersen & Hansen, Torben, 2023, In: Danish Medical Journal. 70, 12, 9 p., A05230332.

    Research output: Contribution to journal › Review › Research › peer-review

  6. Published

    Genome-wide association analyses define pathogenic signaling pathways and prioritize drug targets for IgA nephropathy

    Kiryluk, K., Sanchez-Rodriguez, E., Zhou, X. J., Zanoni, F., Liu, L., Mladkova, N., Khan, A., Marasa, M., Zhang, J. Y., Balderes, O., Sanna-Cherchi, S., Bomback, A. S., Canetta, P. A., Appel, G. B., Radhakrishnan, J., Trimarchi, H., Sprangers, B., Cattran, D. C., Reich, H., Pei, Y. & 168 others, Ravani, P., Galesic, K., Maixnerova, D., Tesar, V., Stengel, B., Metzger, M., Canaud, G., Maillard, N., Berthoux, F., Berthelot, L., Pillebout, E., Monteiro, R., Nelson, R., Wyatt, R. J., Smoyer, W., Mahan, J., Samhar, A. A., Hidalgo, G., Quiroga, A., Weng, P., Sreedharan, R., Selewski, D., Davis, K., Kallash, M., Vasylyeva, T. L., Rheault, M., Chishti, A., Ranch, D., Wenderfer, S. E., Samsonov, D., Claes, D. J., Akchurin, O., Goumenos, D., Stangou, M., Nagy, J., Kovacs, T., Fiaccadori, E., Amoroso, A., Barlassina, C., Cusi, D., Del Vecchio, L., Battaglia, G. G., Bodria, M., Boer, E., Bono, L., Boscutti, G., Caridi, G., Lugani, F., Ghiggeri, G. M., Coppo, R., Peruzzi, L., Esposito, V., Esposito, C., Feriozzi, S., Polci, R., Frasca, G., Galliani, M., Garozzo, M., Mitrotti, A., Gesualdo, L., Granata, S., Zaza, G., Londrino, F., Magistroni, R., Pisani, I., Magnano, A., Marcantoni, C., Messa, P., Mignani, R., Pani, A., Ponticelli, C., Roccatello, D., Salvadori, M., Salvi, E., Santoro, D., Gembillo, G., Savoldi, S., Spotti, D., Zamboli, P., Izzi, C., Alberici, F., Delbarba, E., Florczak, M., Krata, N., Mucha, K., Pączek, L., Niemczyk, S., Moszczuk, B., Pańczyk-Tomaszewska, M., Mizerska-Wasiak, M., Perkowska-Ptasińska, A., Bączkowska, T., Durlik, M., Pawlaczyk, K., Sikora, P., Zaniew, M., Kaminska, D., Krajewska, M., Kuzmiuk-Glembin, I., Heleniak, Z., Bullo-Piontecka, B., Liberek, T., Dębska-Slizien, A., Hryszko, T., Materna-Kiryluk, A., Miklaszewska, M., Szczepańska, M., Dyga, K., Machura, E., Siniewicz-Luzeńczyk, K., Pawlak-Bratkowska, M., Tkaczyk, M., Runowski, D., Kwella, N., Drożdż, D., Habura, I., Kronenberg, F., Prikhodina, L., van Heel, D., Fontaine, B., Cotsapas, C., Wijmenga, C., Franke, A., Annese, V., Gregersen, P. K., Parameswaran, S., Weirauch, M., Kottyan, L., Harley, J. B., Suzuki, H., Narita, I., Goto, S., Lee, H., Kim, D. K., Kim, Y. S., Park, J. H., Cho, B. L., Choi, M., Van Wijk, A., Huerta, A., Ars, E., Ballarin, J., Lundberg, S., Vogt, B., Mani, L. Y., Caliskan, Y., Barratt, J., Abeygunaratne, T., Kalra, P. A., Gale, D. P., Panzer, U., Rauen, T., Floege, J., Schlosser, P., Ekici, A. B., Eckardt, K. U., Chen, N., Xie, J., Lifton, R. P., Loos, Ruth, Kenny, E. E., Ionita-Laza, I., Köttgen, A., Julian, B. A., Novak, J., Scolari, F., Zhang, H. & Gharavi, A. G., 2023, In: Nature Genetics. 55, 7, p. 1091-1105 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Genome-wide association study and functional characterization identifies candidate genes for insulin-stimulated glucose uptake

    Williamson, A., Norris, D. M., Yin, X., Broadaway, K. A., Moxley, A. H., Vadlamudi, S., Wilson, E. P., Jackson, A. U., Ahuja, V., Andersen, M. K., Arzumanyan, Z., Bonnycastle, L. L., Bornstein, S. R., Bretschneider, M. P., Buchanan, T. A., Chang, Y-C., Chuang, L-M., Chung, R-H., Clausen, T. D., Damm, P. & 31 others, Delgado, G. E., de Mello, V. D., Dupuis, J., Dwivedi, O. P., Erdos, M. R., Silva, L. F., Frayling, T. M., Gieger, C., Goodarzi, M. O., Guo, X., Gustafsson, S., Hakaste, L., Hammar, U., Hatem, G., Herrmann, S., Højlund, K., Horn, K., Jonsson, Anna Elisabet, Kovacs, P., Linneberg, Allan René, Mathiesen, Elisabeth, Friis, Carsten, Stinson, Sara, Suleman, Sufyan, Vistisen, D., Witte, D. R., Hansen, Torben, Lind, L., Schwarz, Peter, Grarup, Niels & Meta-Analysis of Glucose and Insulin-related Traits Consortium (MAGIC), M. O. G. A. I. T. C. (., 2023, In: Nature Genetics. 55, 6, p. 973-983 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Genome-wide association study of placental weight identifies distinct and shared genetic influences between placental and fetal growth

    Beaumont, R. N., Flatley, C., Vaudel, M., Wu, X., Chen, J., Moen, G. H., Skotte, L., Helgeland, Ø., Solé-Navais, P., Banasik, K., Albiñana, C., Ronkainen, J., Fadista, J., Stinson, S. E., Trajanoska, K., Wang, C. A., Westergaard, D., Srinivasan, S., Sánchez-Soriano, C., Bilbao, J. R. & 68 others, Allard, C., Groleau, M., Kuulasmaa, T., Leirer, D. J., White, F., Jacques, P. É., Cheng, H., Hao, K., Andreassen, O. A., Åsvold, B. O., Atalay, M., Bhatta, L., Bouchard, L., Brumpton, B. M., Brunak, Søren, Bybjerg-Grauholm, J., Ebbing, C., Elliott, P., pjx571, pjx571, Erikstrup, C., Estarlich, M., Franks, S., Gaillard, R., Geller, F., Grove, J., Hougaard, D. M., Kajantie, E., Morgen, C. S., Nohr, E. A., Nyegaard, Mette, Palmer, C. N. A., Pedersen, Ole Birger Vesterager, Rivadeneira, F., Sebert, S., Shields, B. M., Stoltenberg, C., Surakka, I., Thørner, L. W., Ullum, H., Vaarasmaki, M., Vilhjalmsson, B. J., Willer, C. J., Lakka, T. A., Gybel-Brask, D., Bustamante, M., Hansen, Torben, Pearson, E. R., Reynolds, R. M., Ostrowski, Sisse Rye, Pennell, C. E., Jaddoe, V. W. V., Felix, J. F., Hattersley, A. T., Melbye, M., Lawlor, D. A., Hveem, K., Werge, Thomas, Nielsen, Henriette Svarre, Magnus, P., Evans, D. M., Jacobsson, B., Järvelin, M. R., Zhang, G., Hivert, M. F., Johansson, S., Freathy, R. M., Feenstra, B. & Njølstad, P. R., 2023, In: Nature Genetics. 55, 11, p. 1807-1819 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Genomic Disorders in CKD across the Lifespan

    Verbitsky, M., Krishnamurthy, S., Krithivasan, P., Hughes, D., Khan, A., Marasà, M., Vena, N., Khosla, P., Zhang, J., Lim, T. Y., Glessner, J. T., Weng, C., Shang, N., Shen, Y., Hripcsak, G., Hakonarson, H., Ionita-Laza, I., Levy, B., Kenny, E. E., Loos, R. J. F. & 11 others, Kiryluk, K., Sanna-Cherchi, S., Crosslin, D. R., Furth, S., Warady, B. A., Igo, R. P., Iyengar, S. K., Wong, C. S., Parsa, A., Feldman, H. I. & Gharavi, A. G., 2023, In: Journal of the American Society of Nephrology : JASN. 34, 4, p. 607-618 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Gestational age and trajectories of body mass index and height from birth through adolescence in the Danish National Birth Cohort

    Vinther, Johan Lerbech, Ekstrøm, Claus Thorn, Sørensen, Thorkild I.A., Kristiansen, Luise Cederkvist, Lawlor, D. A. & Nybo Andersen, Anne-Marie, 2023, In: Scientific Reports. 13, 10 p., 3298.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Gestational age at birth and body size from infancy through adolescence: An individual participant data meta-analysis on 253,810 singletons in 16 birth cohort studies

    Vinther, J. L., Cadman, T., Avraam, D., Ekstrøm, C. T., I A Sørensen, T., Elhakeem, A., Santos, A. C., Pinot de Moira, A., Heude, B., Iñiguez, C., Pizzi, C., Simons, E., Voerman, E., Corpeleijn, E., Zariouh, F., Santorelli, G., Inskip, H. M., Barros, H., Carson, J., Harris, J. R. & 27 others, Nader, J. L., Ronkainen, J., Strandberg-Larsen, Katrine, Santa-Marina, L., Calas, L., Kristiansen, Luise Cederkvist, Popovic, M., Charles, M., Welten, M., Vrijheid, M., Azad, M., Subbarao, P., Burton, P., Mandhane, P. J., Huang, R., Wilson, R. C., Haakma, S., Fernández-Barrés, S., Turvey, S., Santos, S., Tough, S. C., Sebert, S., Moraes, T. J., Salika, T., Jaddoe, V. W. V., Lawlor, D. A. & Nybo Andersen, Anne-Marie, 2023, In: PLoS Medicine. 20, 1, 27 p., e1004036.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Global Biobank analyses provide lessons for developing polygenic risk scores across diverse cohorts

    Wang, Y., Namba, S., Lopera-Maya, E. A., Kerminen, S., Tsuo, K., Läll, K., Kanai, M., Zhou, W., Wu, K. H. H., Favé, M. J., Bhatta, L., Awadalla, P., Brumpton, B. M., Deelen, P., Hveem, K., Lo Faro, V., Mägi, R., Murakami, Y., Sanna, S., Smoller, J. W. & 49 others, Uzunovic, J., Wolford, B. N., Wu, K. H. H., Rasheed, H., Hirbo, J. B., Bhattacharya, A., Zhao, H., Surakka, I., Lopera-Maya, E. A., Chapman, S. B., Karjalainen, J., Kurki, M., Mutaamba, M., Partanen, J. J., Brumpton, B. M., Chavan, S., Chen, T. T., Daya, M., Ding, Y., Feng, Y. C. A., Gignoux, C. R., Graham, S. E., Hornsby, W. E., Ingold, N., Johnson, R., Laisk, T., Lin, K., Lv, J., Millwood, I. Y., Loos, Ruth, BBJ, B., BioMe, B., BioVU, B., Canadian Partnership for Tomorrow's Health/OHS, C. P. F. T. H., China Kadoorie Biobank Collaborative Group, C. K. B. C. G., Colorado Center for Personalized Medicine, C. C. F. P. M., deCODE Genetics, D. G., ESTBB, E., FinnGen, F., Generation Scotland, G. S., Genes & Health, G. &. H., LifeLines, L., Mass General Brigham Biobank, M. G. B. B., Michigan Genomics Initiative, M. G. I., QIMR Berghofer Biobank, Q. B. B., Taiwan Biobank, T. B., The HUNT Study, T. H. S., UCLA ATLAS Community Health Initiative, U. A. C. H. I. & UKBB, U., 2023, In: Cell Genomics. 3, 1, 18 p., 100241.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Glucagon 100 years. Important, but still enigmatic

    Holst, Jens Juul, 2023, In: Peptides. 161, 6 p., 170942.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Glucagon-like peptide-1 receptor agonists: role in the prevention and treatment of diabetes-related cardiovascular complications

    Lubberding, Anniek Frederike, Holst, Jens Juul & Madsbad, Sten, 2023, Cardiovascular Endocrinology and Metabolism: Theory and Practice of Cardiometabolic Medicine. Elsevier, p. 365-396

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  15. Published

    Glucose Controls Glucagon Secretion by Regulating Fatty Acid Oxidation in Pancreatic α-Cells

    Armour, Sarah Louise, Frueh, A., Chibalina, M. V., Dou, H., Argemi Muntadas, Lidia, Hamilton, Alexander, Katzilieris Petras, Georgios, Carmeliet, P., Davies, B., Moritz, Thomas, Eliasson, L., Rorsman, P. & Knudsen, Jakob Grunnet, 2023, In: Diabetes. 72, 10, p. 1446-1459 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Glucose Transport and Utilization in the Hippocampus: From Neurophysiology to Diabetes-Related Development of Dementia

    Yonamine, Caio Yogi, Michalani, M. L. E., Moreira, R. J. & Machado, U. F., 2023, In: International Journal of Molecular Sciences. 24, 22, 24 p., 16480.

    Research output: Contribution to journal › Review › Research › peer-review

  17. Published

    Glucose metabolism, gut-brain hormones, and acromegaly treatment: an explorative single centre descriptive analysis

    Jørgensen, N. T., Erichsen, T. M., Jørgensen, M. B., Idorn, T., Feldt-Rasmussen, Bo, Holst, Jens Juul, Feldt-Rasmussen, Ulla & Klose, M., 2023, In: Pituitary. 26, p. 152–163

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Gut Microbiota Contribution to Weight-Independent Glycemic Improvements after Gastric Bypass Surgery

    Hankir, M. K., Kovatcheva-Datchary, P., Springer, R., Hoffmann, A., Vogel, J., Seyfried, F. & Arora, Tulika, 2023, In: Microbiology Spectrum. 11, 3, 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Gut bacterial metabolism contributes to host global purine homeostasis

    Kasahara, K., Kerby, R. L., Zhang, Q., Pradhan, M., Mehrabian, M., Lusis, A. J., Bergström, G., Bäckhed, F. & Rey, F. E., 2023, In: Cell Host and Microbe. 31, 6, p. 1038-1053.e10

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Hepatic Glucose Production, Ureagenesis, and Lipolysis Quantified using the Perfused Mouse Liver Model

    Winther-Sørensen, Marie, Kemp, I. M., Bisgaard, Hanne Cathrine, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2023, In: Journal of Visualized Experiments. 2023, 200, e65596.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Hepatoprotective effects of the long-acting fibroblast growth factor 21 analog PF-05231023 in the GAN diet-induced obese and biopsy-confirmed mouse model of nonalcoholic steatohepatitis

    Nielsen, M. H., Gillum, M. P., Vrang, N., Jelsing, J., Hansen, H. H., Feigh, M. & Oró, D., 2023, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 324, 5, p. G378-G388 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    High Plasma Levels of Soluble Lectin-like Oxidized Low-Density Lipoprotein Receptor-1 Are Associated With Inflammation and Cardiometabolic Risk Profiles in Pediatric Overweight and Obesity

    Stinson, Sara, Jonsson, Anna Elisabet, Lepola, Mette Andersen, Lund, Morten Asp Vonsild, Holm, L. A., Fonvig, Cilius Esmann, Huang, Yun, Stankevic, Evelina, Juel, H. B., Ängquist, Lars, Sørensen, Thorkild I.A., Ongstad, E. L., Gaddipati, R., Grimsby, J., Rhodes, C. J., Pedersen, Oluf Borbye, Christiansen, M., Holm, Jens-Christian & Hansen, Torben, 2023, In: Journal of the American Heart Association. 12, 3, p. 538-544 22 p., e8145.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    High anti-SARS-CoV-2 seroprevalence among unvaccinated mother-child pairs from a rural setting of north-eastern Tanzania during the second wave of COVID-19

    Msemo, O. A., Pérez-Alós, L., Minja, D. T. R., Hansen, Cecilie Bo, Gesase, S., Mtove, G., Mbwana, J., Larsen, V. M. L., Bøgestad, E. C. S., Grunnet, Louise Groth, Christensen, Dirk Lund, Bygbjerg, Ib Christian, Burgner, D., Schmiegelow, Christentze, Garred, Peter & Hjort, Line, 2023, In: IJID Regions (Online). 6, p. 48-57 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    High-throughput proteomics uncovers exercise training and type 2 diabetes-induced changes in human white adipose tissue

    Larsen, Jeppe Kjærgaard, Kruse, R., Sahebekhtiari, N., Moreno Justicia, Roger, Jorba, G. G., Petersen, M. H., de Almeida, M. E., Ørtenblad, N., Deshmukh, Atul Shahaji & Højlund, K., 2023, In: Science Advances. 9, 48, 16 p., eadi7548.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Hyperglucagonaemia and amino acid alterations in individuals with type 2 diabetes and non-alcoholic fatty liver disease

    Rix, I., Johansen, M. L., Lund, A., Suppli, M. P., Chabanova, E., van Hall, Gerrit, Holst, Jens Juul, Albrechtsen, Nicolai Jacob Wewer, Kistorp, Caroline Michaela Nervil & Knop, Filip Krag, 2023, In: Endocrine Connections. 13, 1, 11 p., e230161.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Hyperhidrosis is associated with sleep disturbances, daytime tiredness, stress, and depression: A retrospective cohort study from the Danish Blood Donor Study

    Henning, M., Ibler, Kristina Sophie, Loft, I., Jennum, Poul, Didriksen, M., Ullum, H., Erikstrup, C., Nielsen, K., Bruun, M. T., Hjalgrim, Henrik, Sørensen, E., Dinh, K., Thørner, L. W., Jemec, Gregor & Pedersen, Oluf Borbye, 2023, In: Journal of the American Academy of Dermatology. 88, 1, p. 196-197

    Research output: Contribution to journal › Comment/debate › Research

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