Novo Nordisk Foundation Center for Basic Metabolic Research

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  1. 2023
  2. Published

    Identification of GDF15 peptide fragments inhibiting GFRAL receptor signaling

    Alexopoulou, Flora, Buch-Månson, N., Pedersen, S. L., Vrang, N., Fink, L. N. & Strømgaard, Kristian, 2023, In: Peptides. 168, 7 p., 171063.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Identification of genetic variants associated with a wide spectrum of phenotypes clinically diagnosed as Sanfilippo and Morquio syndromes using whole genome sequencing

    Gul, Rutaba, Firasat, S., Schubert, Mikkel, Ullah, A., Peña Lozano, Elionora, Thuesen, Anne Cathrine Baun, Gjesing, A. P., Hussain, M., Tufail, M., Saqib, M., Afshan, K. & Hansen, Torben, 2023, In: Frontiers in Genetics. 14, 14 p., 1254909.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Identification of pathogenic GCK variants in patients with common type 2 diabetes can lead to discontinuation of pharmacological treatment

    Thuesen, Anne Cathrine Baun, Jensen, Rasmus Tanderup, Maagensen, H., Kristiansen, M. R., Sørensen, H. T., Vaag, Allan, Beck-Nielsen, H., Pedersen, Oluf Borbye, Grarup, Niels, Nielsen, J. S., Rungby, Jørgen, Gjesing, A. P., Storgaard, H., Vilsbøll, Tina & Hansen, Torben, 2023, In: Molecular Genetics and Metabolism Reports. 35, 8 p., 100972.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Identifying the genetic causes of phenotypically diagnosed Pakistani mucopolysaccharidoses patients by whole genome sequencing

    Gul, Rutaba, Firasat, S., Schubert, Mikkel, Ullah, A., Peña, E., Thuesen, Anne Cathrine Baun, Hussain, M., Stæger, Frederik Filip Vinggaard, Gjesing, A. P., Albrechtsen, Anders & Hansen, Torben, 2023, In: Frontiers in Genetics. 14, 13 p., 1128850.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Impact of individual and environmental factors on dietary or lifestyle interventions to prevent type 2 diabetes development: a systematic review

    Bodhini, D., Morton, R. W., Santhakumar, V., Nakabuye, Mariam, Pomares-Millan, H., Clemmensen, Christoffer, Fitzpatrick, S. L., Guasch Ferre, Marta, Pankow, J. S., Ried-Larsen, M., Franks, P. W., Tobias, D. K., Merino, Jordi, Mohan, V., Loos, Ruth & ADA/EASD PMDI, A. P., 2023, In: Communications Medicine. 3, 17 p., 133.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Improving Mitochondrial Function in Skeletal Muscle Contributes to the Amelioration of Insulin Resistance by Nicotinamide Riboside

    Li, Q., Jiang, Xuye, Zhou, Y., Gu, Y., Ding, Y., Luo, J., Pang, N., Sun, Y., Pei, L., Pan, J., Gao, M., Ma, S., Xiao, Y., Hu, D., Wu, F. & Yang, L., 2023, In: International Journal of Molecular Sciences. 24, 12, 19 p., 10015.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    In Vitro Screening for Probiotic Properties of Lactobacillus and Bifidobacterium Strains in Assays Relevant for Non-Alcoholic Fatty Liver Disease Prevention

    Lopez-Escalera, S., Lund, M. L., Hermes, G. D. A., Choi, Beatrice So-Yun, Sakamoto, Kei & Wellejus, A., 2023, In: Nutrients. 15, 10, 23 p., 2361.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Increased Insulin Secretion and Glucose Effectiveness in Obese Patients with Type 2 Diabetes following Bariatric Surgery

    Visentin, R., Brodersen, K., Richelsen, B., Møller, N., Dalla Man, C., Pedersen, A. K., Abrahamsen, J., Holst, Jens Juul & Nielsen, M. F., 2023, In: Journal of Diabetes Research. 2023, 14 p., 127426.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Increased meal-induced neurotensin response predicts successful maintenance of weight loss: Data from a randomized controlled trial

    Brethvad, Annemette Overgaard, Zakariassen, Hannah Louise, Holt, Joachim, Lundgren, J. R., Jakobsen, A., Hartmann, Bolette, Lehmann, E. W., Kissow, Hannelouise, Holst, Jens Juul, Madsbad, Sten, Torekov, Signe Sørensen & Holst, Birgitte, 2023, In: Metabolism: Clinical and Experimental. 143, 8 p., 155534.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Incretin-based therapy of metabolic disease

    Holst, Jens Juul, 2023, In: Danish Medical Journal. 70, 1, A10220597.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Individuals with type 2 diabetes have higher density of small intestinal neurotensin-expressing cells

    Ferreira, F. P., Pereira, S. S., Costa, M. M., Guimarães, M., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Nora, M. & Monteiro, M. P., 2023, In: Molecular and Cellular Biochemistry. 478, 12, p. 2779-2787

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Insufficient sleep predicts poor weight loss maintenance after one year

    Bogh, A. F., Jensen, Simon Birk Kjær, Juhl, C. R., Janus, C., Sandsdal, Rasmus Michael, Lundgren, J. R., Noer, M. H., Vu, N. Q., Fiorenza, Matteo, Stallknecht, Bente Merete, Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, 2023, In: Sleep. 46, 5, 12 p., zsac295.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Insulinotropic effect of endogenously secreted incretins after gastric bypass and sleeve gastrectomy

    Madsbad, Sten & Holst, Jens Juul, 2023, In: Obesity. 31, 11, p. 2723-2724 2 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  15. Published

    Interwoven challenges of covid-19, poor diet, and cardiometabolic health

    Piernas, C. & Merino, Jordi, 2023, In: BMJ. 383, 5 p., 076810.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Is lactate a driver of skin burn-induced adipose browning?

    Lund, Jens, Johansen, Valdemar Brimnes Ingemann, Clemmensen, Christoffer & Gerhart-Hines, Zach, 2023, In: American Journal of Physiology - Endocrinology and Metabolism. 325, 4, p. E421-E422 2 p.

    Research output: Contribution to journal › Comment/debate › Research

  17. Published

    Ketolysis drives CD8+ T cell effector function through effects on histone acetylation

    Luda, K. M., Longo, J., Kitchen-Goosen, S. M., Duimstra, L. R., Ma, E. H., Watson, M. J., Oswald, B. M., Fu, Z., Madaj, Z., Kupai, A., Dickson, B. M., DeCamp, L. M., Dahabieh, M. S., Compton, S. E., Teis, R., Kaymak, I., Lau, K. H., Kelly, D. P., Puchalska, P., Williams, K. S. & 7 others, Krawczyk, C. M., Lévesque, D., Boisvert, F. M., Sheldon, R. D., Rothbart, S. B., Crawford, P. A. & Jones, R. G., 2023, In: Immunity. 56, 9, p. 2021-2035.e8 24 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Ketone monoester increases circulating levels of LEAP2 and decreases appetite in healthy men

    Holm, Stephanie Kjærulff, Vestergaard, E. T., Zubanovic, N. B., Byberg, Sarah, Clemmensen, Christoffer, Holst, Birgitte & Thomsen, H. H., 2023, In: Diabetes, Obesity and Metabolism. 25, 7, p. :2023–2027

    Research output: Contribution to journal › Letter › Research › peer-review

  19. Published

    LEAP2 is associated with cardiometabolic markers but is unchanged by antidiabetic treatment in people with prediabetes

    Byberg, Sarah, Blond, Martin Bæk, Holm, Stephanie Kjærulff, Amadid, H., Nielsen, L. B., Clemmensen, K. K. B., Færch, K. & Holst, Birgitte, 2023, In: American journal of physiology. Endocrinology and metabolism. 325, 3, p. E244-E251

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Lactate receptor GPR81 drives breast cancer growth and invasiveness through regulation of ECM properties and Notch ligand DLL4

    Jørgensen, Kathrine Lundø, Dmytriyeva, O., Spøhr, L., Alves, Eliana Carolina Goncalves, Yao, Jiayi, Puig Blasco, Laia, Trauelsen, Mette, Ponniah, M., Severin, M., Sandelin, Albin Gustav, Kveiborg, Marie, Schwartz, Thue W. & Pedersen, Stine Helene Falsig, 2023, In: BMC Cancer. 23, 1, 20 p., 1136.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Linking Hypothermia and Altered Metabolism with TrkB Activation

    Alitalo, O., González-Hernández, G., Rosenholm, Marko, Kohtala, P., Matsui, N., Müller, H. K., Theilmann, W., Klein, A., Kärkkäinen, O., Rozov, S., Rantamäki, T. & Kohtala, S., 2023, In: ACS Chemical Neuroscience. 14, 17, p. 3212–3225

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Liraglutide changes postprandial responses of gut hormones involved in the regulation of gallbladder motility

    Nerild, H. H., Brønden, Andreas, Gether, I. M., Hellmann, P. H., Baekdal, M., Gillum, M. P., Svenningsen, J. S., Hartmann, Bolette, Rathor, N., Kudiyanur Muniraju, H. A., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina, Sonne, David Peick & Knop, Filip Krag, 2023, In: Diabetes, Obesity and Metabolism. 25, 6, p. 1632-1637

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Liraglutide treatment for the prevention of glucose tolerance deterioration in women with prior gestational diabetes mellitus: A 52-week randomized controlled clinical trial

    Foghsgaard, S., Vedtofte, L., Andersen, E. S., Bahne, E., Andreasen, C., Sørensen, A. L., Forman, Julie Lyng, Mathiesen, Elisabeth, Svare, J. A., Clausen, Tine Dalsgaard, Damm, Peter, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2023, In: Diabetes, Obesity and Metabolism. 26, 1, p. 201-214 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Loci for insulin processing and secretion provide insight into type 2 diabetes risk

    Broadaway, K. A., Yin, X., Williamson, A., Parsons, V. A., Wilson, E. P., Moxley, A. H., Vadlamudi, S., Varshney, A., Jackson, A. U., Ahuja, V., Bornstein, S. R., Corbin, L. J., Delgado, G. E., Dwivedi, O. P., Silva, L. F., Frayling, T. M., Grallert, H., Gustafsson, S., Hakaste, L., Hammar, U. & 51 others, Herder, C., Herrmann, S., Højlund, K., Hughes, D. A., Kleber, M. E., Lindgren, C. M., Liu, C. T., Luan, J., Malmberg, A., Moissl, A. P., Morris, A. P., Perakakis, N., Peters, A., Petrie, J. R., Roden, M., Schwarz, P. E. H., Sharma, S., Silveira, A., Strawbridge, R. J., Tuomi, T., Wood, A. R., Wu, P., Zethelius, B., Baldassarre, D., Eriksson, J. G., Fall, T., Florez, J. C., Fritsche, A., Gigante, B., Hamsten, A., Kajantie, E., Laakso, M., Lahti, J., Lawlor, D. A., Lind, L., März, W., Meigs, J. B., Sundström, J., Timpson, N. J., Wagner, R., Walker, M., Wareham, N. J., Watkins, H., Barroso, I., O'Rahilly, S., Grarup, Niels, Parker, S. C., Boehnke, M., Langenberg, C., Wheeler, E. & Mohlke, K. L., 2023, In: American Journal of Human Genetics. 110, 2, p. 284-299 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Long-acting agonists of human and rodent GLP-2 receptors for studies of the physiology and pharmacological potential of the GLP-2 system

    Gadgaard, S., Windeløv, Johanne Agerlin, Schiellerup, S. P., Holst, Jens Juul, Hartmann, Bolette & Rosenkilde, Mette, 2023, In: Biomedicine and Pharmacotherapy. 160, 13 p., 114383.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Loss of the Secretin Receptor Impairs Renal Bicarbonate Excretion and Aggravates Metabolic Alkalosis in Mice during Acute Base-Loading

    Berg, P., Jensen, T., Andersen, J. F., Svendsen, S. L., Modvig, Ida Marie, Wang, T., Frische, S., Chow, B. K. C., Malte, H., Holst, Jens Juul, Sørensen, M. V. & Leipziger, J., 2023, In: Journal of the American Society of Nephrology : JASN. 34, 8, p. 1329-1342 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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