Novo Nordisk Foundation Center for Basic Metabolic Research

  1. 2023
  2. Published

    Low birthweight is associated with a higher incidence of type 2 diabetes over two decades independent of adult BMI and genetic predisposition

    Wibaek, R., Andersen, G. S., Linneberg, Allan René, Hansen, Torben, Grarup, Niels, Thuesen, Anne Cathrine Baun, Jensen, Rasmus Tanderup, Wells, J. C. K., Pilgaard, Kasper Ascanius, Brøns, C., Vistisen, D. & Vaag, Allan, 2023, In: Diabetologia. 66, p. 1669–1679 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Machine learning models for blood pressure phenotypes combining multiple polygenic risk scores

    Hrytsenko, Y., Shea, B., Elgart, M., Kurniansyah, N., Lyons, G., Morrison, A. C., Carson, A. P., Haring, B., Mitchel, B. D., Psaty, B. M., Jaeger, B. C., Gu, C. C., Kooperberg, C., Levy, D., Lloyd-Jones, D., Choi, E., Brody, J. A., Smith, J. A., Rotter, J. I., Moll, M. & 18 others, Fornage, M., Simon, N., Castaldi, P., Casanova, R., Chung, R., Kaplan, R., Loos, Ruth, Kardia, S. L. R., Rich, S. S., Redline, S., Kelly, T., O'Connor, T., Zhao, W., Kim, W., Guo, X., Chen, Y. D. I., Sofer, T. & Trans-Omics in Precision Medicine Consortium, T. I. P. M. C., 2023, medRxiv, 41 p.

    Research output: Working paperPreprintResearch

  4. Published

    Male reproductive traits are differentially affected by dietary macronutrient balance but unrelated to adiposity

    Crean, A. J., Afrin, S., Niranjan, H., Pulpitel, T. J., Ahmad, G., Senior, A. M., Freire, T., Mackay, F., Nobrega, M. A., Barrès, Romain, Simpson, S. J. & Pini, T., 2023, In: Nature Communications. 14, 1, 12 p., 2566.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Markers of Glucagon Resistance Improve With Reductions in Hepatic Steatosis and Body Weight in Type 2 Diabetes

    Kjeldsen, Sasha Alexandra Sampson, Thomsen, M. N., Skytte, M. J., Samkani, A., Richter, Michael Martin, Frystyk, J., Magkos, Faidon, Hansen, E., Thomsen, Henrik S., Holst, Jens Juul, Madsbad, Sten, Haugaard, Steen Bendix, Krarup, T. & Albrechtsen, Nicolai Jacob Wewer, 2023, In: Journal of the Endocrine Society. 7, 11, 11 p., bvad122.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Markers of inflammation predict survival in newly diagnosed cirrhosis: a prospective registry study

    Mynster Kronborg, T., Webel, Henry, O’Connell, M. B., Danielsen, K. V., Hobolth, L., Møller, Søren, Jensen, Rasmus Tanderup, Bendtsen, Flemming, Hansen, Torben, Rasmussen, Simon, Juel, H. B. & Kimer, N., 2023, In: Scientific Reports. 13, 11 p., 20039.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Maturity-onset diabetes of the young og graviditet

    Kauffmann, A., Jørgensen, I. L., Thuesen, Anne Cathrine Baun, Ringholm, Lene, Clausen, Tine Dalsgaard, Mathiesen, Elisabeth, Hansen, Torben & Damm, Peter, 2023, In: Ugeskrift for Laeger. 185, 21, V02230067.

    Research output: Contribution to journalReviewResearchpeer-review

  8. Published

    Meal sugar-protein balance determines postprandial FGF21 response in humans

    Ramne, Stina, Duizer, Lisanne, Nielsen, M. S., Jørgensen, Niklas Rye, Svenningsen, J. S., Grarup, Niels, Sjödin, Anders Mikael, Raben, Anne & Gillum, M. P., 2023, In: American Journal of Physiology - Endocrinology and Metabolism. 325, 5, p. E491-E499

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Meal timing of dietary total antioxidant capacity and its association with all-cause, CVD and cancer mortality: the US national health and nutrition examination survey, 1999–2018

    Wang, P., Jiang, Xuye, Tan, Q., Du, S. & Shi, D., 2023, In: International Journal of Behavioral Nutrition and Physical Activity. 20, 13 p., 83.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Metabolic Dysregulation in Adult Survivors of Pediatric Hematopoietic Stem Cell Transplantation: The Role of Incretins

    Vadmand, A. C., Nissen, A. A., Mathiesen, S., Ebbesen, M. S., Gerbek, T., Fridh, M. K., Sørensen, K., Hartmann, Bolette, Holst, Jens Juul & Muller, Klaus, 2023, In: Journal of Clinical Endocrinology and Metabolism. 108, 2, p. 453–462

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Metabolic Profiling Early Post-Allogeneic Haematopoietic Cell Transplantation in the Context of CMV Infection

    Rasmussen, K. K., dos Santos, Q., MacPherson, C. R., Zucco, Adrian G., Gjærde, L. K., Ilett, Emma Elizabeth, Lodding, I., Helleberg, Marie, Lundgren, Jens, Nielsen, S. D., Brix, S., Sengeløv, Henrik & Murray, D. D., 2023, In: Metabolites. 13, 9, 11 p., 968.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Metabolic changes and propensity for inflammation, fibrosis, and cancer in livers of mice lacking lysosomal acid lipase

    Bradić, I., Liesinger, L., Kuentzel, K. B., Vujić, N., Trauner, M., Birner-Gruenberger, R. & Kratky, D., 2023, In: Journal of Lipid Research. 64, 9, 12 p., 100427.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Metabolism and Art

    Rogers, Hannah Star & Bencard, Adam, 2023, In: Leonardo. 56, 4, p. 388–390 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Methylome and proteome integration in human skeletal muscle uncover group and individual responses to high-intensity interval training

    Jacques, M., Landen, S., Romero, J. A., Hiam, D., Schittenhelm, R. B., Hanchapola, I., Shah, A. D., Voisin, S. & Eynon, N., 2023, In: FASEB Journal. 37, 10, 18 p., e23184.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Microbial dietary protein metabolism regulates GLP-1 mediated intestinal transit

    Toft, P. B., Yashiro, H., Erion, D. M., Gillum, M. P., Bäckhed, F. & Arora, Tulika, 2023, In: FASEB Journal. 37, 10, 8 p., e23201.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Microbial metabolite p-cresol inhibits gut hormone expression and regulates small intestinal transit in mice

    Toft, P. B., Vanslette, A. M., Trošt, K., Moritz, Thomas, Gillum, M. P., Bäckhed, F. & Arora, Tulika, 2023, In: Frontiers in Endocrinology. 14, 7 p., 1200391.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Microbially Produced Imidazole Propionate Is Associated With Heart Failure and Mortality

    Molinaro, A., Nemet, I., Bel Lassen, P., Chakaroun, R., Nielsen, T., Aron-Wisnewsky, J., Bergh, P. O., Li, L., Henricsson, M., Køber, Lars Valeur, Isnard, R., Helft, G., Stumvoll, M., Pedersen, Oluf Borbye, Smith, J. G., Tang, W. H. W., Clément, K., Hazen, S. L., Bäckhed, F. & MetaCardis Consortium, M. C., 2023, In: JACC: Heart Failure. 11, 7, p. 810-821 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Middle ear effusion, ventilation tubes and neurological development in childhood

    Thorsen, Jonathan Jan Ilve, Pedersen, T. M., Cecilie Mora-Jensen, A. R., Bjarnadó ttir, E., Bager, S. C., Bisgaard, H. & Stokholm, Jakob, 2023, In: PLoS ONE. 18, 1, 14 p., e0280199.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Migration mediated by the oxysterol receptor GPR183 depends on arrestin coupling but not receptor internalization

    Kjær, Viktoria Madeline Skovgaard, Daugvilaite, V., Stepniewski, T. M., Madsen, C. M., Jørgensen, Astrid Sissel, Bhuskute, K. R., Inoue, A., Ulven, Trond, Benned-Jensen, T., Hjorth, Siv Annegrethe, Hjortø, Gertrud Malene, Moo, Ee Von, Selent, J. & Rosenkilde, Mette, 2023, In: Science Signaling. 16, 779, 13 p., eabl4283.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Mitochondrial phosphatidylethanolamine modulates UCP1 to promote brown adipose thermogenesis

    Johnson, J. M., Peterlin, A. D., Balderas, E., Sustarsic, E. G., Maschek, J. A., Lang, M. J., Jara-Ramos, A., Panic, V., Morgan, J. T., Villanueva, C. J., Sanchez, A., Rutter, J., Lodhi, I. J., Cox, J. E., Fisher-Wellman, K. H., Chaudhuri, D., Gerhart-Hines, Zach & Funai, K., 2023, In: Science Advances. 9, 8, 15 p., eade7864.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Molecular Connectomics Reveals a Glucagon-Like Peptide 1 Sensitive Neural Circuit for Satiety

    Webster, A. N., Becker, J. J., Li, C., Schwalbe, D. C., Kerspern, D., Karolczak, E. O., Godschall, E. N., Belmont-Rausch, Dylan Matthew, Pers, Tune H, Lutas, A., Habib, N., Güler, A. D., Krashes, M. J. & Campbell, J. N., 2023, bioRxiv, 47 p.

    Research output: Working paperPreprintResearch

  22. Published
  23. Published
  24. Published

    Monoamines' role in islet cell function and type 2 diabetes risk

    Roberts, F. L., Cataldo, L. R. & Fex, M., 2023, In: Trends in Molecular Medicine. 29, 12, p. 1045-1058 14 p.

    Research output: Contribution to journalReviewResearchpeer-review

  25. Published

    Mosaic chromosomal alterations in blood across ancestries using whole-genome sequencing

    Jakubek, Y. A., Zhou, Y., Stilp, A., Bacon, J., Wong, J. W., Ozcan, Z., Arnett, D., Barnes, K., Bis, J. C., Boerwinkle, E., Brody, J. A., Carson, A. P., Chasman, D. I., Chen, J., Cho, M., Conomos, M. P., Cox, N., Doyle, M. F., Fornage, M., Guo, X. & 31 others, Kardia, S. L. R., Lewis, J. P., Loos, Ruth, Ma, X., Machiela, M. J., Mack, T. M., Mathias, R. A., Mitchell, B. D., Mychaleckyj, J. C., North, K., Pankratz, N., Peyser, P. A., Preuss, M. H., Psaty, B., Raffield, L. M., Vasan, R. S., Redline, S., Rich, S. S., Rotter, J. I., Silverman, E. K., Smith, J. A., Smith, A. P., Taub, M., Taylor, K. D., Yun, J., Li, Y., Desai, P., Bick, A. G., Reiner, A. P., Scheet, P. & Auer, P. L., 2023, In: Nature Genetics. 55, 11, p. 1912-1919 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications

    VA Million Veteran Program, V. M. V. P., 2023, medRxiv, 39 p.

    Research output: Working paperPreprintResearch