Novo Nordisk Foundation Center for Basic Metabolic Research

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  1. 2022
  2. Published

    MIntO: A Modular and Scalable Pipeline For Microbiome Metagenomic and Metatranscriptomic Data Integration

    Saenz, C., Nigro, E., Gunalan, V. & Arumugam, Mani, 2022, In: Frontiers in Bioinformatics. 2, 15 p., 846922.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Macrophage activation marker sCD163 is associated with liver injury and hepatic insulin resistance in obese patients before and after Roux-en-Y gastric bypass

    Kazankov, K., Bojsen-Møller, K. N., Møller, H. J., Madsbad, Sten & Grønbæk, H., 2022, In: Physiological Reports. 10, 2, 11 p., e15157.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Mapping the cord blood transcriptome of pregnancies affected by early maternal anemia to identify signatures of fetal programming

    Hatem, G., Hjort, Line, Asplund, O., Minja, D. T. R., Msemo, O. A., Møller, S. L., Lavstsen, Thomas, Grunnet, Louise Groth, Lusingu, J. P. A., Hansson, O., Christensen, Dirk Lund, Vaag, Allan, Artner, I., Theander, Thor Grundtvig, Groop, L., Schmiegelow, Christentze, Bygbjerg, Ib Christian & Prasad, R. B., 2022, In: The Journal of clinical endocrinology and metabolism. 107, 5, p. 1303–1316 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Marked gut microbiota dysbiosis and increased imidazole propionate are associated with a NASH Göttingen Minipig model

    Lützhøft, Ditte Olsen, Sinioja, T., Christoffersen, B., Jakobsen, Rasmus Riemer, Geng, Dawei, Ahmad, H. F. B., Straarup, E. M., Pedersen, K. M., Kot, Witold, Pedersen, H. D., Cirera, Susanna, Hyötyläinen, T., Nielsen, Dennis Sandris & Hansen, Axel Kornerup, 2022, In: BMC Microbiology. 22, 1, 287.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Mechanism of glycogen synthase inactivation and interaction with glycogenin

    Marr, L., Biswas, Dipsikha, Daly, L. A., Browning, C., Vial, S. C. M., Maskell, D. P., Hudson, C., Bertrand, J. A., Pollard, J., Ranson, N. A., Khatter, H., Eyers, C. E., Sakamoto, Kei & Zeqiraj, E., 2022, In: Nature Communications. 13, 1, 14 p., 3372.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Mechanistic basis of GPCR activation explored by ensemble refinement of crystallographic structures

    Madsen, J. J., Ye, L., Frimurer, Thomas Michael & Olsen, O. H., 2022, In: Protein Science. 31, 11, 16 p., e4456.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Mendelian randomization suggests a bidirectional, causal relationship between physical inactivity and adiposity

    Carrasquilla, Germán D., García Ureña, Mario, Fall, T., Sørensen, Thorkild I.A. & Kilpeläinen, Tuomas O., 2022, In: eLife. 11, 25 p., e70386.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Mendelian randomization suggests a bidirectional, causal relationship between physical inactivity and obesity

    Carrasquilla, Germán D., García Ureña, Mario, Fall, T., Sørensen, Thorkild I.A. & Kilpeläinen, Tuomas O., 2022, (bioRxiv).

    Research output: Working paper › Research

  10. Published

    Mendelian randomization suggests a causal effect of abdominal obesity on postprandial lipemia

    Christiansen, Malene Revsbech, Hansen, Torben, Sørensen, Thorkild I.A., Grarup, Niels, García Ureña, Mario, Borisevich, D., Oppert, J., Martinez Hernandez, J. A., Blaak, E. & Kilpeläinen, Tuomas O., 2022, In: European Journal of Human Genetics. 30, Supplement 1, p. 184 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  11. Published

    Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of indeterminate potential

    Nakao, T., Bick, A. G., Taub, M. A., Zekavat, S. M., Uddin, M. M., Niroula, A., Carty, C. L., Lane, J., Honigberg, M. C., Weinstock, J. S., Pampana, A., Gibson, C. J., Griffin, G. K., Clarke, S. L., Bhattacharya, R., Assimes, T. L., Emery, L. S., Stilp, A. M., Wong, Q., Broome, J. & 32 others, Laurie, C. A., Khan, A. T., Smith, A. V., Blackwell, T. W., Codd, V., Nelson, C. P., Yoneda, Z. T., Peralta, J. M., Bowden, D. W., Irvin, M. R., Boorgula, M., Zhao, W., Yanek, L. R., Wiggins, K. L., Hixson, J. E., Charles Gu, C., Peloso, G. M., Roden, D. M., Reupena, M. S., Hwu, C. M., DeMeo, D. L., North, K. E., Kelly, S., Musani, S. K., Bis, J. C., Lloyd-Jones, D. M., Johnsen, J. M., Preuss, M., Tracy, R. P., Loos, Ruth, The Samoan Obesity, Lifestyle and Genetic Adaptations Study (OLaGA) Group, T. S. O. L. A. G. A. S. (. G. & NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, N. T. F. P. M. (. C., 2022, In: Science Advances. 8, 14, eabl6579.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Mesenchymal-epithelial crosstalk shapes intestinal regionalisation via Wnt and Shh signalling

    Maimets, Martti, Pedersen, M. T., Guiu, J., Dreier, J., Thodberg, Malte, Antoku, Yasuko, Schweiger, P. J., Rib, Leonor, Bardini Bressan, Raul, Miao, Y., Garcia, K. C., Sandelin, Albin Gustav, Serup, Palle & Jensen, Kim Bak, 2022, In: Nature Communications. 13, 12 p., 715.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Meta-analysis of epigenome-wide association studies in newborns and children show widespread sex differences in blood DNA methylation

    Solomon, O., Huen, K., Yousefi, P., Küpers, L. K., González, J. R., Suderman, M., Reese, S. E., Page, C. M., Gruzieva, O., Rzehak, P., Gao, L., Bakulski, K. M., Novoloaca, A., Allard, C., Pappa, I., Llambrich, M., Vives, M., Jima, D. D., Kvist, T., Baccarelli, A. & 65 others, White, C., Rezwan, F. I., Sharp, G. C., Tindula, G., Bergström, A., Grote, V., Dou, J. F., Isaevska, E., Magnus, M. C., Corpeleijn, E., Perron, P., Jaddoe, V. W. V., Nohr, E. A., Maitre, L., Foraster, M., Hoyo, C., Håberg, S. E., Lahti, J., DeMeo, D. L., Zhang, H., Karmaus, W., Kull, I., Koletzko, B., Feinberg, J. I., Gagliardi, L., Bouchard, L., Ramlau-Hansen, C. H., Tiemeier, H., Santorelli, G., Maguire, R. L., Czamara, D., Litonjua, A. A., Langhendries, J. P., Plusquin, M., Lepeule, J., Binder, E. B., Verduci, E., Dwyer, T., Carracedo, Á., Ferre, N., Eskenazi, B., Kogevinas, M., Nawrot, T. S., Munthe-Kaas, M. C., Herceg, Z., Relton, C., Melén, E., Gruszfeld, D., Breton, C., Fallin, M. D., Ghantous, A., Nystad, W., Heude, B., Snieder, H., Hivert, M. F., Felix, J. F., Sørensen, Thorkild I.A., Bustamante, M., Murphy, S. K., Raikkönen, K., Oken, E., Holloway, J. W., Arshad, S. H., London, S. J. & Holland, N., 2022, In: Mutation Research - Reviews in Mutation Research. 789, 108415.

    Research output: Contribution to journal › Review › Research › peer-review

  14. Published

    Metabolic and Genetic Risk Factors Are the Strongest Predictors of Severity of Alcohol-Related Liver Fibrosis

    Israelsen, M., Juel, H. B., Detlefsen, S., Madsen, B. S., Rasmussen, D. N., Larsen, T. R., Kjærgaard, M., Fernandes Jensen, M. J., Stender, S., Hansen, Torben, Krag, A., Thiele, M. & GALAXY and MicrobLiver consortiak, G. A. M. C., 2022, In: Clinical Gastroenterology and Hepatology. 20, 8, p. 1784-1794.e9 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Metabolic control of arginine and ornithine levels paces the progression of leaf senescence

    Liebsch, D., Juvany, M., Li, Z., Wang, H., Ziolkowska, A., Chrobok, D., Boussardon, C., Wen, X., Law, S. R., Janečková, H., Brouwer, B., Lindén, P., Delhomme, N., Stenlund, H., Moritz, Thomas, Gardeström, P., Guo, H. & Keech, O., 2022, In: Plant Physiology. 189, 4, p. 1943-1960

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Metabolite G-protein coupled receptor signaling: Potential regulation of eicosanoids

    Tang, X., Hou, Y., Schwartz, Thue W. & Haeggström, J. Z., 2022, In: Biochemical Pharmacology. 204, 7 p., 115208.

    Research output: Contribution to journal › Review › Research › peer-review

  17. Published

    Metabolomic and microbiome profiling reveals personalized risk factors for coronary artery disease

    Talmor-Barkan, Y., Bar, N., Shaul, A. A., Shahaf, N., Godneva, A., Bussi, Y., Lotan-Pompan, M., Weinberger, A., Shechter, A., Chezar-Azerrad, C., Arow, Z., Hammer, Y., Chechi, K., Forslund, S. K., Fromentin, S., Dumas, M. E., Ehrlich, S. D., Pedersen, Oluf Borbye, Kornowski, R. & Segal, E., 2022, In: Nature Medicine. 28, 2, p. 295-302 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Metagenomic evidence for co-occurrence of antibiotic, biocide and metal resistance genes in pigs

    Li, Xuan Ji, Rensing, C., Vestergaard, G., Arumugam, Mani, Nesme, Joseph, Gupta, S., Brejnrod, A. D. & Sørensen, Søren Johannes, 2022, In: Environment International. 158, 10 p., 106899.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Methods in Bioarchaeology: What’s New in Profiling an Individual Inside and Out

    Freiwald, C., Belanich, Jonathan Robert & Rand, A., 2022, The Routledge Handbook of Mesoamerican Bioarchaeology. Tieslar, V. (ed.). Routledge, p. 577-600 24 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  20. Published

    MicroRNAs in non-alcoholic fatty liver disease: Progress and perspectives

    Hochreuter, Mette Yde, Dall, M., Treebak, Jonas Thue & Barrès, Romain, 2022, In: Molecular Metabolism. 65, 17 p., 101581.

    Research output: Contribution to journal › Review › Research › peer-review

  21. Published

    Microbiome and metabolome features of the cardiometabolic disease spectrum

    Fromentin, S., Forslund, S. K., Chechi, K., Aron-Wisnewsky, J., Chakaroun, R., Nielsen, T., Tremaroli, V., Ji, B., Prifti, E., Myridakis, A., Chilloux, J., Andrikopoulos, P., Fan, Y., Olanipekun, M. T., Alves, R., Adiouch, S., Bar, N., Talmor-Barkan, Y., Belda, E., Caesar, R. & 44 others, Coelho, L. P., Falony, G., Fellahi, S., Galan, P., Galleron, N., Helft, G., Hoyles, L., Isnard, R., Le Chatelier, E., Julienne, H., Olsson, L., Pedersen, H. K., Pons, N., Quinquis, B., Rouault, C., Roume, H., Salem, J. E., Schmidt, T. S. B., Vieira-Silva, S., Li, P., Zimmermann-Kogadeeva, M., Lewinter, C., Søndertoft, N. B., Hansen, T. H., Gauguier, D., Gøtze, J. P., Køber, Lars Valeur, Kornowski, R., drb459, drb459, Hansen, Torben, Zucker, J. D., Hercberg, S., Letunic, I., Bäckhed, F., Oppert, J. M., Nielsen, J., Raes, J., Bork, P., Stumvoll, M., Segal, E., Clément, K., Dumas, M. E., Ehrlich, S. D. & Pedersen, Oluf Borbye, 2022, In: Nature Medicine. 28, 2, p. 303-314

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Microbiome-derived ethanol in nonalcoholic fatty liver disease

    Meijnikman, A. S., Davids, M., Herrema, H., Aydin, O., Tremaroli, V., Rios-Morales, M., Levels, H., Bruin, S., de Brauw, M., Verheij, J., Kemper, M., Holleboom, A. G., Tushuizen, M. E., Schwartz, T. W., Nielsen, J., Brandjes, D., Dirinck, E., Weyler, J., Verrijken, A., De Block, C. E. M. & 7 others, Vonghia, L., Francque, S., Beuers, U., Gerdes, V. E. A., Bäckhed, F., Groen, A. K. & Nieuwdorp, M., 2022, In: Nature Medicine. 28, p. 2100-2106

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Mild Cognitive Impairment Is Associated with Poorer Nutritional Status on Hospital Admission and after Discharge in Acutely Hospitalized Older Patients

    Bornæs, O., Andersen, A. L., Houlind, Morten Baltzer, Kallemose, T., Tavenier, J., Aharaz, A., Nielsen, Rikke Linnemann, Jørgensen, L. M., Beck, A. M., Andersen, Ove, Petersen, Janne & Pedersen, Mette Merete, 2022, In: Geriatrics (Switzerland). 7, 5, 16 p., 95.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Mixed-mode chromatography-mass spectrometry enables targeted and untargeted screening of carboxylic acids in biological samples

    Hodek, O., Argemi Muntadas, Lidia, Khan, Adnan & Moritz, Thomas, 2022, In: Analytical Methods. 14, 10, p. 1015-1022 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Modeling the early stages of Alzheimer's disease by administering intracerebroventricular injections of human native A beta oligomers to rats

    Baerends, E., Soud, K., Folke, J., Pedersen, A., Henmar, S., Konrad, Lisa, Lycas, M. D., Mori, Yuki, Pakkenberg, B., Woldbye, David Paul Drucker, Dmytriyeva, O. & Pankratova, Stanislava, 2022, In: Acta Neuropathologica Communications. 10, 1, 21 p., 113.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Modulation of gut microbiota by Mantequilla and Melipona honeys decrease low-grade inflammation caused by high fructose corn syrup or sucrose in rats

    Coutiño-Hernández, D., Sánchez-Tapia, M., Leal-Vega, F., Bobadilla del Valle, M., Ledezma, H., Cervantes, R., Pedraza-Chaverri, J., Granados-Portillo, O., Díaz, D., Antunes-Ricardo, M., Gutiérrez-Uribe, J., Maya, Otoniel, Olin-Sandoval, V., Tovar, A. R. & Torres, N., 2022, In: Food Research International. 151, 13 p., 110856.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Molecular Insights into the Role of Pathogenic nsSNPs in GRIN2B Gene Provoking Neurodevelopmental Disorders

    Shah, A. A., Amjad, M., Hassan, J. U., Ullah, A., Mahmood, A., Deng, H., Ali, Y., Gul, F. & Xia, K., 2022, In: Genes. 13, 8, 21 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Molecular and in vivo phenotyping of missense variants of the human glucagon receptor

    van der Velden, W. J. C., Lindquist, Peter, Madsen, Jakob Sture, Stassen, R. H. M. J., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Hauser, Alexander Sebastian & Rosenkilde, M. M., 2022, In: Journal of Biological Chemistry. 298, 2, 101413.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Monogenic diabetes variants in Emirati women with gestational diabetes are associated with risk of non-autoimmune diabetes within 5 years after pregnancy

    Daggag, H., Gjesing, A. P., Mohammad, A., Ängquist, Lars, Shobi, B., Antony, S., Haj, D., Al Tikriti, A., Buckley, A., Hansen, Torben & Barakat, M. T., 2022, In: Metabolism open. 16, 7 p., 100213.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

    Mahajan, A., Spracklen, C. N., Zhang, W., Ng, M. C. Y., Petty, L. E., Kitajima, H., Yu, G. Z., Rüeger, S., Speidel, L., Kim, Y. J., Horikoshi, M., Mercader, J. M., Taliun, D., Moon, S., Kwak, S-H., Robertson, N. R., Rayner, N. W., Loh, M., Kim, B-J., Chiou, J. & 31 others, Miguel-Escalada, I., Della Briotta Parolo, P., Lin, K., Bragg, F., Preuss, M. H., Takeuchi, F., Nano, J., Guo, X., Lamri, A., Nakatochi, M., Scott, R. A., Lee, J., Huerta-Chagoya, A., Graff, M., Chai, J., Parra, E. J., Yao, J., Bielak, L. F., Grarup, Niels, Chen, W., Bork-Jensen, J., Islam, M. T., Jørgensen, M. E., Jørgensen, T., Linneberg, Allan René, Witte, D. R., Lind, L., Loos, Ruth, Hansen, Torben, Pedersen, Oluf Borbye & FinnGen, F., 2022, In: Nature Genetics. 54, 5, p. 560-572 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Multi-component prime-boost Chlamydia trachomatis vaccination regimes induce antibody and T cell responses and accelerate clearance of infection in a non-human primate model

    Lorenzen, E., Contreras, V., Olsen, A. W., Andersen, P., Desjardins, D., Rosenkrands, I., Juel, H. B., Delache, B., Langlois, S., Delaugerre, C., Joubert, C., Dereuddre-Bosquet, N., Bébéar, C., De Barbeyrac, B., Touati, A., McKay, P. F., Shattock, R. J., Le Grand, R., Follmann, F. & Dietrich, J., 2022, In: Frontiers in Immunology. 13, 13 p., 1057375.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Multiomics and digital monitoring during lifestyle changes reveal independent dimensions of human biology and health

    Marabita, F., James, T., Karhu, A., Virtanen, H., Kettunen, K., Stenlund, H., Boulund, F., Hellström, C., Neiman, M., Mills, R., Perheentupa, T., Laivuori, H., Helkkula, P., Byrne, M., Jokinen, I., Honko, H., Kallonen, A., Ermes, M., Similä, H., Lindholm, M. & 9 others, Widén, E., Ripatti, S., Perälä-Heape, M., Engstrand, L., Nilsson, P., Moritz, Thomas, Miettinen, T., Sallinen, R. & Kallioniemi, O., 2022, In: Cell Systems. 13, 3, p. 241-255.e7

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Multiomics signatures of type 1 diabetes with and without albuminuria

    Clos-Garcia, M., Ahluwalia, Tarun Veer Singh, Winther, S. A., Henriksen, P., Ali, M., Fan, Yong, Stankevic, Evelina, Lyu, Liwei, Vogt, J. K., Hansen, Torben, Legido-Quigley, C., Rossing, Peter & Pedersen, Oluf Borbye, 2022, In: Frontiers in Endocrinology. 13, 17 p., 1015557.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    N-terminal alterations turn the gut hormone GLP-2 into an antagonist with gradual loss of GLP-2 receptor selectivity towards more GLP-1 receptor interaction

    Gabe, M. B. N., Gasbjerg, Lærke Smidt, Gadgaard, S., Lindquist, Peter, Holst, Jens Juul & Rosenkilde, Mette, 2022, In: British Journal of Pharmacology. 179, 18, p. 4473-4485

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    NAD+ and NAFLD - Caution, Causality, and Careful Optimism

    Dall, M., Hassing, Anna Skab & Treebak, Jonas Thue, 2022, In: The Journal of Physiology. 600, 5, p. 1135-1154

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Natural (dihydro)phenanthrene plant compounds are direct activators of AMPK through its allosteric drug and metabolite–binding site

    Sanders, M. J., Ratinaud, Y., Neopane, K., Bonhoure, N., Day, E. A., Ciclet, O., Lassueur, S., Pinta, M. N., Deak, M., Brinon, B., Christen, S., Steinberg, G. R., Barron, D. & Sakamoto, Kei, 2022, In: Journal of Biological Chemistry. 298, 5, 15 p., 101852.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Neonatal Anthropometrics and Obesity Treatment Response in Children and Adolescents

    Lausten-Thomsen, U., Lund, Morten Asp Vonsild, Stinson, Sara, Frithioff-Bøjsøe, C., Holm, L. A., Baker, J. L., Fonvig, Cilius Esmann, Christiansen, M., Ängquist, Lars, Hansen, Torben & Holm, Jens-Christian, 2022, In: Journal of Pediatrics. 242, p. 74-78.e2 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Neurotensin secretion after Roux-en-Y gastric bypass, sleeve gastrectomy, and truncal vagotomy with pyloroplasty

    Svane, M. S., Øhrstrøm, C. C., Plamboeck, A., Jørgensen, Nils Bruun, Bojsen-Møller, K. N., Dirksen, C., Martinussen, C., Vilsbøll, Tina, Hartmann, Bolette, Deacon, Carolyn F., Kristiansen, V. B., Knop, Filip Krag, Svendsen, Lars Bo, Madsbad, Sten, Holst, Jens Juul & Veedfald, Simon, 2022, In: Neurogastroenterology and Motility. 34, 1, e14210.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Noninvasive proteomic biomarkers for alcohol-related liver disease

    Niu, Lili, Thiele, M., Geyer, P. E., Rasmussen, D. N., Webel, Henry, Santos, A., Gupta, R., Meier, F., Strauss, Maximilian, Kjaergaard, M., Lindvig, K., Jacobsen, S., Rasmussen, Simon, Hansen, Torben, Krag, A. & Mann, Matthias, 2022, In: Nature Medicine. 28, 6, p. 1277-1287 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Novel agonist- and antagonist-based radioligands for the GLP-2 receptor - useful tools for studies of basic GLP-2R pharmacology

    Gadgaard, S., van der Velden, W. J. C., Schiellerup, S. P., Dal, Jenna Elizabeth Hunt, Gabe, M. B. N., Windeløv, Johanne Agerlin, Boer, G. A., Kissow, Hannelouise, Ørskov, Cathrine, Holst, Jens Juul, Hartmann, Bolette & Rosenkilde, M. M., 2022, In: British Journal of Pharmacology. 179, 9, p. 1998-2015

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    OZITX, a pertussis toxin-like protein for occluding inhibitory G protein signalling including Gαz

    Keen, A. C., Pedersen, M. H., Lemel, L., Scott, D. J., Canals, M., Littler, D. R., Beddoe, T., Ono, Y., Shi, L., Inoue, A., Javitch, J. A. & Lane, J. R., 2022, In: Communications Biology . 5, 1, 10 p., 256.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Off-label Prescription, Adverse Drug Events and Dosage of Psychotropic Drugs in Children and Adolescents with Obesity: A Retrospective Cohort Study

    Kamronn, T. M., Gade, Christina, Nielsen, S., Christensen, H. R., Dalhoff, Kim, Holm, Jens-Christian & Holst, H., 2022, In: Acta Scientific Pharmaceutical Sciences. 6, 6, p. 4-16 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    On measurements of glucagon secretion in healthy, obese, and Roux-en-Y gastric bypass operated individuals using sandwich ELISA

    Albrechtsen, Nicolai Jacob Wewer, Kjeldsen, Sasha Alexandra Sampson, Jensen, N. J., Rungby, Jørgen, Veedfald, Simon, Bojsen-Møller, K. N., Dirksen, C., Jensen, Christian Zinck, Martinussen, C., Madsbad, Sten & Holst, Jens Juul, 2022, In: Scandinavian Journal of Clinical & Laboratory Investigation. 82, 1, p. 75-83

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Opposing effects of chronic glucagon receptor agonism and antagonism on amino acids, hepatic gene expression, and alpha cells

    Elmelund, E., Galsgaard, Katrine Douglas, Johansen, C. D., Trammell, Sam, Billeschou, Anna, Winther-Sørensen, Marie, Dal, Jenna Elizabeth Hunt, Sorensen, Charlotte Mehlin, Kruse, Thomas, Lau, J. F., Grevengoed, Trisha Jean, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2022, In: iScience. 25, 11, 20 p., 105296.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Opposing effects on regulated insulin secretion of acute vs chronic stimulation of AMP-activated protein kinase

    Nguyen-Tu, M., Harris, J., Martinez-Sanchez, A., Chabosseau, P., Hu, M., Georgiadou, E., Pollard, A., Otero, P., Lopez-Noriega, L., Leclerc, I., Sakamoto, Kei, Schmoll, D., Smith, D. M., Carling, D. & Rutter, G. A., 2022, In: Diabetologia. 65, p. 997-1011 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Opposing roles of the entero-pancreatic hormone urocortin-3 in glucose metabolism in rats

    Grunddal, Kaare Villum, Trammell, Sam, Bæch-Laursen, C., Andersen, Daniel Bjørklund, Xu, S. F. S., Andersen, H., Gillum, M. P., Ghiasi, S. M., Novak, Ivana, Tyrberg, B., Li, C., Rosenkilde, Mette, Hartmann, Bolette, Holst, Jens Juul & Kuhre, Rune Ehrenreich, 2022, In: Diabetologia. 65, p. 1018–1031

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Optimization of First-in-Class Dual-Acting FFAR1/FFAR4 Allosteric Modulators with Novel Mode of Action

    Lückmann, Michael, Iliyaz, Aslihan Shenol, Nissen, T. A. D., Petersen, Jacob Emil, Kouvchinov, David, Schwartz, Thue W. & Frimurer, Thomas Michael, 2022, In: ACS Medicinal Chemistry Letters. 13, 12, p. 1839-1847

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Organ-specific metabolic pathways distinguish prediabetes, type 2 diabetes, and normal tissues

    Diamanti, K., Cavalli, M., Pereira, M. J., Pan, G., Castillejo-López, C., Kumar, C., Mundt Madsen, Filip Oskar, Komorowski, J., Deshmukh, Atul Shahaji, Mann, Matthias, Korsgren, O., Eriksson, J. W. & Wadelius, C., 2022, In: Cell Reports Medicine. 3, 10, 21 p., 100763.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Outrunning obesity with Lac-Phe?

    Lund, Jens, Clemmensen, Christoffer & Schwartz, Thue W., 2022, In: Cell Metabolism. 34, 8, p. 1085-1087 3 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  50. Published

    PEN2: Metformin’s new partner at lysosome

    Sakamoto, Kei & Jessen, N., 2022, In: Cell Research. 32, p. 507-508

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    PRDM16 stability and metabolically healthy adipose tissue

    Horvath, C. & Schéele, Camilla Charlotte Nielsen, 2022, In: Nature Metabolism. 4, p. 1095-1096

    Research output: Contribution to journal › Comment/debate › Research

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