- 2020
- Published
Relationship between biochemical and symptomatic hypoglycemia after RYGB. Responses to a mixed meal test: a case-control study
Søeby, M., Nielsen, J. B., Pedersen, S. B., Gribsholt, S. B., Holst, Jens Juul & Richelsen, B., 2020, In: Surgery for Obesity and Related Diseases. 16, 9, p. 1179-1185 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reply
Villumsen, M., Jess, T. & Allin, K. H., 2020, In: Clinical Gastroenterology and Hepatology. 18, 4, p. 1003-1004Research output: Contribution to journal › Comment/debate › Research
- Published
Responses of gut and pancreatic hormones, bile acids, and fibroblast growth factor-21 differ to glucose, protein, and fat ingestion after gastric bypass surgery
Jensen, C. Z., Bojsen-Møller, K. N., Svane, M. S., Holst, L. M., Hermansen, K., Hartmann, Bolette, Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Kristiansen, V. B., Rehfeld, Jens Frederik, Clausen, T. R., Holst, Jens Juul & Madsbad, Sten, 2020, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 318, 4, p. G661-G672 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Risk of pancreatitis in patients with inflammatory bowel disease - a meta-analysis
Pedersen, J. E., Ängquist, Lars, Jensen, C. B., Kjærgaard, J. S., Jess, T. & Allin, K. H., 2020, In: Danish Medical Journal. 67, 3, 6 p., A08190427.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of Energy Excretion in Human Body Weight Regulation
Lund, Jens, Gerhart-Hines, Zach & Clemmensen, Christoffer, 2020, In: Trends in Endocrinology and Metabolism. 31, 10, p. 705-708 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of fasting duration and weekday in incretin and glucose regulation
Clemmensen, K. K. B., Quist, J. S., Vistisen, D., Witte, D. R., Jonsson, Anna Elisabet, Pedersen, Oluf Borbye, Hansen, Torben, Holst, Jens Juul, Lauritzen, T., Jørgensen, M. E., Torekov, Signe Sørensen & Færch, K., 2020, In: Endocrine Connections. 9, 4, p. 279-288Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Secretin release after Roux-en-Y gastric bypass reveals a population of glucose-sensitive S cells in distal small intestine
Modvig, Ida Marie, Andersen, Daniel Bjørklund, Grunddal, Kaare Villum, Kuhre, Rune Ehrenreich, Martinussen, C., Christiansen, Charlotte Bayer, Ørskov, Cathrine, Larraufie, P., Kay, R. G., Reimann, F., Gribble, F. M., Hartmann, Bolette, Bojsen-Moller, K. N., Madsbad, Sten, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2020, In: International Journal of Obesity. 44, 9, p. 1859-1871Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Secretion of parathyroid hormone may be coupled to insulin secretion in humans
Sass, M. R., Albrechtsen, Nicolai Jacob Wewer, Pedersen, Jens, Hare, Kristine Juul, Borbye-Lorenzen, N., Kiss, K., Vilsbøll, Tina, Knop, Filip Krag, Poulsen, Steen Seier, Jørgensen, Niklas Rye, Holst, Jens Juul, Ørskov, Cathrine & Hartmann, Bolette, 2020, In: Endocrine Connections. 9, 7, p. 747-754Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Selective inhibitors of SIRT2 regulate perinuclear α-tubulin acetylation, migration, and invasion of breast cancer cells
Nielsen, A. L., Rajabi, N., Kudo, N., Jørgensen, Kathrine Lundø, Fontenas, M., Lucidi, A., Madsen, A. S., Yoshida, M. & Olsen, Christian Adam, 2020, In: bioRxiv. 26 p.Research output: Contribution to journal › Journal article › Research
- Published
Simulating the Post-gastric Bypass Intestinal Microenvironment Uncovers a Barrier-Stabilizing Role for FXR
Hankir, M. K., Langseder, T., Bankoglu, E. E., Ghoreishi, Y., Dischinger, U., Kurlbaum, M., Kroiss, M., Otto, C., le Roux, C. W., Arora, Tulika, Seyfried, F. & Schlegel, N., 2020, In: iScience. 23, 12, 32 p., 101777.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Six-day subcutaneous GIP infusion increases glycaemic time in range in patients with type 1 diabetes
Heimbuerger, S. M. N., Hoe, B., Nielsen, C. N., Bergmann, N. C., Hartmann, Bolette, Holst, Jens Juul, Størling, Joachim, Vilsbøll, Tina, Dejgaard, T. F., Christensen, Mikkel Bring & Knop, Filip Krag, 2020, In: Diabetologia. 63, SUPPL 1, p. S73 1 p., 145.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Skeletal muscle enhancer interactions identify genes controlling whole-body metabolism
Williams, K., Ingerslev, L. R., Bork-Jensen, J., Wohlwend, M., Hansen, Ann Normann, Small, Lewin Barkla, Ribel-Madsen, R., Astrup, A., Pedersen, Oluf Borbye, Auwerx, J., Workman, C. T., Grarup, Niels, Hansen, Torben & Barrès, Romain, 2020, In: Nature Communications. 11, 16 p., 2695.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Statin therapy is associated with lower prevalence of gut microbiota dysbiosis
Vieira-Silva, S., Falony, G., Belda, E., Nielsen, T., Aron-Wisnewsky, J., Chakaroun, R., Forslund, S. K., Assmann, K., Valles-Colomer, M., Nguyen, T. T. D., Proost, S., Prifti, E., Tremaroli, V., Pons, N., Le Chatelier, E., Andreelli, F., Bastard, J-P., Coelho, L. P., Galleron, N., Hansen, T. H. & 28 others, , 2020, In: Nature. 581, 7808, p. 310-315Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Statins for cirrhosis: almost ready for clinical application
Kimer, N., Kronborg, T. M., Bendtsen, Flemming & Møller, Søren, 2020, In: Digestive Medicine Research. 3, 4 p., 111.Research output: Contribution to journal › Editorial › Research
- Published
Structural basis for GPCR signaling by small polar versus large lipid metabolites-discovery of non-metabolite ligands
Lückmann, Michael, Trauelsen, Mette, Frimurer, Thomas Michael & Schwartz, Thue W., 2020, In: Current Opinion in Cell Biology. 63, p. 38-48Research output: Contribution to journal › Review › Research › peer-review
- Published
Structured exercise alters the gut microbiota in humans with overweight and obesity - A randomized controlled trial
Kern, T., Blond, Martin Bæk, Hansen, T. H., Rosenkilde, M., Quist, Jonas Salling, Gram, A. S., Ekstrøm, Claus Thorn, Hansen, Torben & Stallknecht, Bente Merete, 2020, In: International Journal of Obesity. 44, p. 125-135 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synthetic G protein-coupled bile acid receptor agonists and bile acids act via basolateral receptors in ileal and colonic mucosa
Tough, I. R., Schwartz, Thue W. & Cox, H. M., 2020, In: Neurogastroenterology and Motility. 32, 12, 14 p., e13943.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Complex Signaling Pathways of the Ghrelin Receptor
Hedegaard, M. A. & Holst, Birgitte, 2020, In: Molecular Endocrinology. 161, 4, 12 p., 020.Research output: Contribution to journal › Review › Research › peer-review
- Published
The Connexin 43 Regulator Rotigaptide Reduces Cytokine-Induced Cell Death in Human Islets
Ghiasi, S. M., Hansen, J. B., Christensen, D. P., Tyrberg, B. & Mandrup-Poulsen, Thomas, 2020, In: International Journal of Molecular Sciences (Online). 21, 12, 15 p., 4311.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Effect of Overweight and Obesity on Liver Biochemical Markers in Children and Adolescents
Johansen, M. J., Gade, J., Stender, Stefan, Frithioff-Bojsoe, C., Lund, M. A., Chabanova, E., Thomsen, Henrik S., Pedersen, Oluf Borbye, Fonvig, C. E., Hansen, Torben & Holm, Jens-Christian, 2020, In: Journal of Clinical Endocrinology & Metabolism. 105, 2, p. 430-442 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls
Coleman, J. R. I., Gaspar, H. A., Bryois, J., Byrne, E. M., Forstner, A. J., Holmans, P. A., de Leeuw, C. A., Mattheisen, M., McQuillin, A., Whitehead Pavlides, J. M., Pers, T. H., Ripke, S., Stahl, E. A., Steinberg, S., Trubetskoy, V., Trzaskowski, M., Wang, Y., Abbott, L., Abdellaoui, A., Adams, M. J. & 32 others, , 2020, In: Biological Psychiatry. 88, 2, p. 169-184 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Gut Microbiota in Prediabetes and Diabetes: A Population-Based Cross-Sectional Study
Wu, H., Tremaroli, V., Schmidt, C., Lundqvist, A., Olsson, L. M., Kramer, M., Gummesson, A., Perkins, R., Bergstrom, G. & Backhed, F., 2020, In: Cell Metabolism. 32, 3, p. 379-390.e3 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Polygenic and Monogenic Basis of Blood Traits and Diseases
Vuckovic, D., Bao, E. L., Akbari, P., Lareau, C. A., Mousas, A., Jiang, T., Chen, M-H., Raffield, L. M., Tardaguila, M., Huffman, J. E., Ritchie, S. C., Megy, K., Ponstingl, H., Penkett, C. J., Albers, P. K., Wigdor, E. M., Sakaue, S., Moscati, A., Manansala, R., Lo, K. S. & 31 others, , 2020, In: Cell. 182, 5, p. 1214-1231 29 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Vicious Circle of Hepatic Glucagon Resistance in Non-Alcoholic Fatty Liver Disease
Galsgaard, Katrine Douglas, 2020, In: Journal of Clinical Medicine. 9, 12, 11 p., 4049.Research output: Contribution to journal › Review › Research › peer-review
- Published
The anti-obesogenic effect of lean fish species is influenced by the fatty acid composition in fish fillets
Fjære, E., Myrmel, L. S., Dybing, K., Kuda, O., Jensen, Benjamin Anderschou Holbech, Rossmeisl, M., Frøyland, L., Kristiansen, Karsten & Madsen, L., 2020, In: Nutrients. 12, 10, 18 p., 3038.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The clinical effects of a carbohydrate-reduced high-protein diet on glycaemic variability in metformin-treated patients with type 2 diabetes mellitus: A randomised controlled study
Thomsen, M. N., fbg982, fbg982, Astrup, A., Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten, Krarup, T., Haugaard, Steen Bendix & Samkani, A., 2020, In: Clinical Nutrition ESPEN. 39, p. 46-52 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The derived allele of a novel intergenic variant at chromosome 11 associates with lower body mass index and a favorable metabolic phenotype in Greenlanders
Andersen, M. K., Jørsboe, E., Skotte, L., Hanghøj, K., Sandholt, C. H., Moltke, I., Grarup, N., Kern, T., Mahendran, Y., Søborg, B., Bjerregaard, P., Larsen, C. V. L., Dahl-Petersen, I. K., Tiwari, H. K., Feenstra, B., Koch, A., Wiener, H. W., Hopkins, S. E., Pedersen, O., Melbye, M. & 4 others, , 2020, In: PLOS Genetics. 16, 1, 17 p., e1008544.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of acute dual SGLT1/SGLT2 inhibition on incretin release and glucose metabolism after gastric bypass surgery
Martinussen, C., Veedfald, Simon, Dirksen, Carsten Moro, Bojsen-Møller, K. N., Svane, M. S., Albrechtsen, Nicolai Jacob Wewer, van Hall, Gerrit, Kristiansen, V. B., Fenger, M., Holst, Jens Juul & Madsbad, Sten, 2020, In: American Journal of Physiology: Endocrinology and Metabolism. 318, 6, p. E956-E964 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of acute intragastric vs. intravenous alcohol administration on inflammation markers, blood lipids and gallbladder motility in healthy men
Lanng, A. R., Gasbjerg, Lærke Smidt, Bergmann, N. C., Gillum, M. P., Rehfeld, Jens Frederik, Helsted, M. M., Møller, H. J., Grønbæk, H., Vilsbøll, Tina & Knop, Filip Krag, 2020, In: Alcohol. 87, p. 29-37 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of diabetes and the common diabetogenic TBC1D4 p.Arg684Ter variant on cardiovascular risk in Inuit in Greenland
Overvad, M., Diaz, L. J., Bjerregaard, P., Pedersen, M. L., Larsen, C. V. L., Senftleber, N., Grarup, Niels, Hansen, Torben & Jørgensen, M. E., 2020, In: Scientific Reports. 10, 9 p., 22081.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The impact of acute glycaemic fluctuations on left ventricular systolic function in insulin-treated type 2 diabetes
Andersen, A., Jorgensen, P. G., Bagger, J. I., Baldassarre, M. P. A., Christensen, M., Abelin, K. U., Faber, Jens, Pedersen-Bjergaard, Ulrik, Holst, Jens Juul, Lindhardt, T., Gislason, Gunnar Hilmar, Knop, Filip Krag & Vilsbøll, Tina, 2020, In: Diabetologia. 63, SUPPL 1, p. S429-S429 897.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
The influence of transmitted and non-transmitted parental BMI-associated alleles on the risk of overweight in childhood
Schnurr, T. M., Morgen, C. S., Borisevich, D., Beaumont, R. N., pjx571, pjx571, Ängquist, Lars, Have, C. T., Freathy, R. M., Smith, G. D., Nohr, E. A., Hansen, Torben & Sørensen, Thorkild I.A., 2020, In: Scientific Reports. 10, 1, 10 p., 4806.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The intestinal microbiome is a co-determinant of the postprandial plasma glucose response
Søndertoft, N. B., Vogt, J. K., Arumugam, Mani, Kristensen, M., Gøbel, R. J., Fan, Yong, Lyu, Liwei, Bahl, M. I., Eriksen, C., Ängquist, Lars, Frøkiær, Hanne, Hansen, T. H., Brix, Susanne, Nielsen, H. B., Hansen, Torben, Vestergaard, H., Gupta, R., Licht, T. R., Lauritzen, Lotte & Pedersen, Oluf Borbye, 2020, In: P L o S One. 15, 9, 23 p., e0238648.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The microbiome of captive hamadryas baboons
Li, Xuan Ji, Trivedi, Urvish, Brejnrod, A. D., Vestergaard, G. A., Mortensen, M. S., Bertelsen, Mads Frost & Sørensen, Søren Johannes, 2020, In: BMC Animal Microbiome. 2, 10 p., 25.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of endogenous GIP and GLP-1 in postprandial bone homeostasis
Helsted, M. M., Gasbjerg, Lærke Smidt, Lanng, A. R., Bergmann, N. C., Stensen, S., Hartmann, Bolette, Christensen, Mikkel Bring, Holst, Jens Juul, Vilsbøll, Tina, Rosenkilde, Mette & Knop, Filip Krag, 2020, In: Bone. 140, 7 p., 115553.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of glucagon in the acute therapeutic effects of SGLT2 inhibition
Hædersdal, S., Lund, A., Nielsen-Hannerup, E., Maagensen, H., van Hall, Gerrit, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2020, In: Diabetes. 69, 12, p. 2619-2629 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of physical activity in metabolic homeostasis before and after the onset of type 2 diabetes: an IMI DIRECT study
Koivula, R. W., Atabaki-Pasdar, N., Giordano, G. N., White, T., Adamski, J., Bell, J. D., Beulens, J., Brage, S., Brunak, S., De Masi, F., Dermitzakis, E. T., Forgie, I. M., Frost, G., Hansen, T., Hansen, T. H., Hattersley, A., Kokkola, T., Kurbasic, A., Laakso, M., Mari, A. & 15 others, , 2020, In: Diabetologia. 63, 4, p. 744-756 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The scaffold protein p62 regulates adaptive thermogenesis through ATF2 nuclear target activation
Fischer, K., Fenzl, A., Liu, D., Dyar, K. A., Kleinert, M., Brielmeier, M., Clemmensen, C., Fedl, A., Finan, B., Gessner, A., Jastroch, M., Huang, J., Keipert, S., Klingenspor, M., Brüning, J. C., Kneilling, M., Maier, F. C., Othman, A. E., Pichler, B. J., Pramme-Steinwachs, I. & 13 others, , 2020, In: Nature Communications. 11, 1, 13 p., 2306.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The unidentified hormonal defense against weight gain
Lund, Jens, Lund, Camilla, Morville, T. H. & Clemmensen, Christoffer, 2020, In: PLOS Biology. 18, 2, 14 p., e3000629.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Three-Dimensional Explant Platform for Studies on Choroid Plexus Epithelium
Petersen, N., Pedersen, Lola Julie Torz, Jensen, Kristian HR, Hjortø, Gertrud Malene, Spiess, Katja & Rosenkilde, Mette, 2020, In: Frontiers in Cellular Neuroscience. 14, 11 p., 108.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Thyroid hormone receptor α in skeletal muscle is essential for T3-mediated increase in energy expenditure
Nicolaisen, T. S., Klein, A. B., Dmytriyeva, O., Lund, Jens, Ingerslev, L. R., Fritzen, Andreas Mæchel, Carl, Christian Strini, Lundsgaard, Anne-Marie, Frost, M., Ma, Tao, Schjerling, P., Gerhart-Hines, Zach, Flamant, F., Gauthier, K., Larsen, Steen, Richter, Erik A., Kiens, Bente & Clemmensen, Christoffer, 2020, In: F A S E B Journal. 34, 11, p. 15480-15491 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Time-restricted feeding alters lipid and amino acid metabolite rhythmicity without perturbing clock gene expression: [Author Correction]
Lundell, L. S., Parr, E. B., Devlin, B. L., Ingerslev, L. R., Altıntaş, Ali, Sato, S., Sassone-Corsi, P., Barrès, Romain, Zierath, Juleen R & Hawley, J. A., 2020, In: Nature Communications. 11, 1, 11 p., 4643.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tirzepatide is an imbalanced and biased dual GIP and GLP-1 receptor agonist
Willard, F. S., Douros, J. D., Gabe, M., Showalter, A. D., Wainscott, D. B., Suter, T. M., Capozzi, M. E., van der Velden, W. J. C., Stutsman, C., Cardona, G. R., Urva, S., Emmerson, P. J., Holst, Jens Juul, D'Alessio, D. A., Coghlan, M. P., Rosenkilde, Mette, Campbell, J. E. & Sloop, K. W., 2020, In: JCI insight. 5, 17, 16 p., 140532.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Train like an athlete: applying exercise interventions to manage type 2 diabetes
Savikj, M. & Zierath, Juleen R, 2020, In: Diabetologia. 63, 8, p. 1491-1499Research output: Contribution to journal › Review › Research › peer-review
- Published
Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations
Chen, M-H., Raffield, L. M., Mousas, A., Sakaue, S., Huffman, J. E., Moscati, A., Trivedi, B., Jiang, T., Akbari, P., Vuckovic, D., Bao, E. L., Zhong, X., Manansala, R., Laplante, V., Chen, M., Lo, K. S., Qian, H., Lareau, C. A., Beaudoin, M., Hunt, K. A. & 31 others, , 2020, In: Cell. 182, 5, p. 1198-+ 30 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcription factor EB and TFE3: new metabolic coordinators mediating adaptive responses to exercise in skeletal muscle?
Markby, G. R. & Sakamoto, Kei, 2020, In: American Journal of Physiology: Endocrinology and Metabolism. 319, 4, p. E763-E768 6 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Transcriptomic analysis links diverse hypothalamic cell types to fibroblast growth factor 1-induced sustained diabetes remission
Bentsen, M. A., Rausch, D. M., Mirzadeh, Z., Muta, K., Scarlett, J. M., Brown, J. M., Herranz-Pérez, V., Baquero, A. F., Thompson, J., Alonge, K. M., Faber, C. L., Kaiyala, K. J., Bennett, C., Pyke, C., Ratner, C., Egerod, K. L., Holst, B., Meek, T. H., Kutlu, B., Zhang, Y. & 9 others, , 2020, In: Nature Communications. 11, 1, 4458.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcriptomic and epigenomics atlas of myotubes reveals insight into the circadian control of metabolism and development
Altıntaş, Ali, Laker, R. C., Garde, C., Barrès, Romain & Zierath, Juleen R, 2020, In: Epigenomics. 12, 8, p. 701-713Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcriptomic profiling of skeletal muscle adaptations to exercise and inactivity
Pillon, N. J., Gabriel, B. M., Dollet, L., Smith, J. A. B., Puig, L. S., Botella, J., Bishop, D. J., Krook, A. & Zierath, Juleen R, 2020, In: Nature Communications. 11, 1, 15 p., 470.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Trust is good, control is better: technical considerations in blood microbiome analysis
Schierwagen, R., Alvarez Silva, Maria Camila, Servant, F., Trebicka, J., Lelouvier, B. & Arumugam, Mani, 2020, In: Gut. 69, 7, p. 1362-1363Research output: Contribution to journal › Letter › Research › peer-review
- Published
Tunneled peritoneal catheter for refractory ascites in cirrhosis: A randomized case-series
Kimer, N., Nordheim Riedel, A., Hobolth, L., Mortensen, C., Madsen, Lone Galmstrup, Andersen, M. L., Schiødt, Frank Vinholt, Møller, Søren & Gluud, Lise Lotte, 2020, In: Medicina. 56, 11, 9 p., 565.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Type 2 diabetes influences bacterial tissue compartmentalisation in human obesity
Anhê, F. F., Jensen, Benjamin Anderschou Holbech, Varin, T. V., Servant, F., Van Blerk, S., Richard, D., Marceau, S., Surette, M., Biertho, L., Lelouvier, B., Schertzer, J. D., Tchernof, A. & Marette, A., 2020, In: Nature Metabolism. 2, 3, p. 233-242 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tænkningens udsving - et essay om at tænke i en pandemisk situation
Grünfeld, Martin, 2020, In: Sundhed og Samfund. 33, p. 167-172 6 p.Research output: Contribution to journal › Journal article › Research
- Published
Universal Dermal Microbiome in Human Skin
Bay, Lene, Barnes, Christopher James, Fritz, Blaine Gabriel, Thorsen, Jonathan Jan Ilve, Restrup, M. E. M., Rasmussen, Linett, Sørensen, J. K., Hesselvig, A. B., Odgaard, Anders, Hansen, Anders Johannes & Bjarnsholt, Thomas, 2020, In: mBio. 11, 1, 13 p., e02945-19.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Urinary markers of nucleic acid oxidation increase with age, obesity and insulin resistance in Danish children and adolescents
Jors, A., Lund, M. A. ,. V., Jespersen, Thomas, Hansen, Torben, Poulsen, Henrik Enghusen & Holm, Jens-Christian, 2020, In: Free Radical Biology and Medicine. 155, p. 81-86Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Use of inhaled corticosteroids and the risk of developing type 2 diabetes in patients with chronic obstructive pulmonary disease
Saeed, M. I., Eklof, J., Achir, I., Sivapalan, P., Meteran, Howraman, Lokke, A., Biering-Sørensen, Tor, Knop, Filip Krag & Jensen , Jens-Ulrik Stæhr , 2020, In: Diabetes, Obesity and Metabolism. 22, 8, p. 1348-1356 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variation in Bile Microbiome by the Etiology of Cholestatic Liver Disease
Tyc, O., Jansen, C., Schierwagen, R., Uschner, F. E., Israelsen, M., Klein, S., Ortiz, C., Strassburg, C. P., Zeuzem, S., Gu, W., Torres, S., Praktiknjo, M., Kersting, S., Langheinrich, M., Nattermann, J., Servant, F., Arumugam, M., Krag, A., Lelouvier, B., Weismueller, T. J. & 1 others, , 2020, In: Liver Transplantation. 26, 12, p. 1652-1657 6 p.Research output: Contribution to journal › Letter › Research
- Published
What is on the horizon for type 2 diabetes pharmacotherapy? - An overview of the antidiabetic drug development pipeline
Johansson, K. S., Sonne, D., Knop, Filip Krag & Christensen, Mikkel Bring, 2020, In: Expert Opinion on Drug Discovery. 15, 11, p. 1253-1265Research output: Contribution to journal › Review › Research › peer-review
- Published
Whole blood co-expression modules associate with metabolic traits and type 2 diabetes: an IMI-DIRECT study
Gudmundsdottir, V., Pedersen, H. K., Mazzoni, G., Allin, K. H., Artati, A., Beulens, J. W., Banasik, K., Brorsson, C., Cederberg, H., Chabanova, E., De Masi, F., Elders, P. J., Forgie, I., Giordano, G. N., Grallert, H., Gupta, R., Haid, M., Hansen, T., Hansen, T. H., Hattersley, A. T. & 36 others, , 2020, In: Genome Medicine. 12, 1, 17 p., 109.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
- Published
Will the COVID-19 pandemic worsen the obesity epidemic?
Clemmensen, Christoffer, Petersen, M. B. & Sørensen, Thorkild I.A., 2020, In: Nature Reviews Endocrinology. 2 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Writing and Thinking in Contemporary Academia: The Poetics of Clarity
Grünfeld, Martin, 2020, Routledge. 168 p. (Public Intellectuals and the Sociology of Knowledge).Research output: Book/Report › Book › peer-review
- Published
scVAE: variational auto-encoders for single-cell gene expression data
Grønbech, Christopher Heje, Vording, M. F., Timshel, P., Sønderby, C. K., Pers, Tune H & Winther, Ole, 2020, In: Bioinformatics. 36, 16, p. 4415-4422 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
snRNA-seq reveals a subpopulation of adipocytes that regulates thermogenesis
Sun, W., Dong, H., Balaz, M., Slyper, M., Drokhlyansky, E., Colleluori, G., Giordano, A., Kovanicova, Z., Stefanicka, P., Balazova, L., Ding, L., Husted, Anna Sofie, Rudofsky, G., Ukropec, J., Cinti, S., Schwartz, Thue W., Regev, A. & Wolfrum, C., 2020, In: Nature. 587, 31 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Author Correction: Metagenomic analysis of colorectal cancer datasets identifies cross-cohort microbial diagnostic signatures and a link with choline degradation (Nature Medicine, (2019), 25, 4, (667-678), 10.1038/s41591-019-0405-7)
Thomas, A. M., Manghi, P., Asnicar, F., Pasolli, E., Armanini, F., Zolfo, M., Beghini, F., Manara, S., Karcher, N., Pozzi, C., Gandini, S., Serrano, D., Tarallo, S., Francavilla, A., Gallo, G., Trompetto, M., Ferrero, G., Mizutani, S., Shiroma, H., Shiba, S. & 19 others, , 1 Dec 2019, In: Nature Medicine. 25, 12, p. 1948 1 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
The CODATwins Project: The Current Status and Recent Findings of COllaborative Project of Development of Anthropometrical Measures in Twins
Silventoinen, K., Jelenkovic, A., Yokoyama, Y., Sund, R., Sugawara, M., Tanaka, M., Matsumoto, S., Bogl, L. H., Freitas, D. L., Maia, J. A., Hjelmborg, J. V. B., Aaltonen, S., Piirtola, M., Latvala, A., Calais-Ferreira, L., Oliveira, V. C., Ferreira, P. H., Ji, F., Ning, F., Pang, Z. & 118 others, , Dec 2019, In: Twin Research and Human Genetics. 22, 6, p. 800-808Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The developing Entorhinal cortex - a cellular map
Bergmann, T. B., Liu, Y., Lee, J., Pfisterer, U. G., Handfield, L., Asenjo Martinez, A., Seemann, Ernst Stefan, Witter, M., Khodosevich, Konstantin, Gorodkin, Jan, Hemberg, M., Pers, Tune H & Hall, Vanessa Jane, 25 Nov 2019. 1 p.Research output: Contribution to conference › Conference abstract for conference › Communication
- Published
Effects of Nicotinamide Riboside on Endocrine Pancreatic Function and Incretin Hormones in Nondiabetic Men With Obesity
Dollerup, O. L., Trammell, Sam, Hartmann, Bolette, Holst, Jens Juul, Christensen, B., Møller, N., Gillum, M. P., Treebak, Jonas Thue & Jessen, N., 1 Nov 2019, In: The Journal of clinical endocrinology and metabolism. 104, 11, p. 5703-5714 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of Xist-mediated Polycomb recruitment in the initiation of X-chromosome inactivation
Bousard, A., Raposo, A. C., Żylicz, J. J., Picard, C., Pires, V. B., Qi, Y., Gil, Cláudia, Syx, L., Chang, H. Y., Heard, E. & da Rocha, S. T., 4 Oct 2019, In: EMBO Reports. 20, 10, e48019.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 associate with gestational duration
Liu, X., Helenius, D., Skotte, L., Beaumont, R. N., Wielscher, M., Geller, F., Juodakis, J., Mahajan, A., Bradfield, J. P., Lin, F. T. J., Vogelezang, S., Bustamante, M., Ahluwalia, T. S., Pitkänen, N., Wang, C. A., Bacelis, J., Borges, M. C., Zhang, G., Bedell, B. A., Rossi, R. M. & 54 others, , 2 Sep 2019, In: Nature Communications. 10, 1, 13 p., 3927.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Author Correction: Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2 (Nature Biotechnology, (2019), 37, 8, (852-857), 10.1038/s41587-019-0209-9)
Bolyen, E., Rideout, J. R., Dillon, M. R., Bokulich, N. A., Abnet, C. C., Al-Ghalith, G. A., Alexander, H., Alm, E. J., Arumugam, M., Asnicar, F., Bai, Y., Bisanz, J. E., Bittinger, K., Brejnrod, A., Brislawn, C. J., Brown, C. T., Callahan, B. J., Caraballo-Rodríguez, A. M., Chase, J., Cope, E. K. & 92 others, , 1 Sep 2019, In: Nature Biotechnology. 37, 9, p. 1091 1 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Editorial: Novel biomarkers for type 2 diabetes
Ahluwalia, T. S., Kilpeläinen, Tuomas O., Singh, S. & Rossing, Peter, 1 Sep 2019, In: Frontiers in Endocrinology. 10, p. 1-3 3 p., 649.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
“Nutrition or no nutrition?”: Chylothorax or leakage of total parenteral nutrition?
Zasada, I. A., Banner, Jytte & Bugge, A., Sep 2019, In: Forensic Science, Medicine, and Pathology. 15, 3, p. 470–473Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure
Sung, Y. J., de Las Fuentes, L., Winkler, T. W., Chasman, D. I., Bentley, A. R., Kraja, A. T., Ntalla, I., Warren, H. R., Guo, X., Schwander, K., Manning, A. K., Brown, M. R., Aschard, H., Feitosa, M. F., Franceschini, N., Lu, Y., Cheng, C-Y., Sim, X., Vojinovic, D., Marten, J. & 263 others, , 1 Aug 2019, In: Human Molecular Genetics. 28, 15, p. 2615-2633Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Augmented GLP-1 Secretion as Seen After Gastric Bypass May Be Obtained by Delaying Carbohydrate Digestion
Martinussen, C., Bojsen-Møller, K. N., Dirksen, C., Svane, M. S., Kristiansen, V. B., Hartmann, Bolette, Holst, Jens Juul & Madsbad, Sten, Aug 2019, In: Journal of Clinical Endocrinology and Metabolism. 104, 8, p. 3233–3244Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma proteome profiling discovers potential biomarkers of non-alcoholic fatty liver disease
Niu, Lili, Gupta, R., Geyer, P. E., Albrechtsen, Nicolai Jacob Wewer, Gluud, Lise Lotte, Santos, A., Doll, S., Holst, Jens Juul, Knop, Filip Krag, Vilsbøll, Tina, Junker, A., Sachs, S., Stemmer, K., Mueller, T. D., Tschoep, M. H., Hofmann, S. M. & Mann, Matthias, Aug 2019, In: Molecular & Cellular Proteomics. 18, 8, p. S71 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Extracellular Fluid Volume Expansion Uncovers a Natriuretic Action of GLP-1: A Functional GLP-1–Renal Axis in Man
Asmar, A., Cramon, P. K., Simonsen, L., Asmar, M., Sorensen, Charlotte Mehlin, Madsbad, Sten, Moro, C., Hartmann, Bolette, Jensen, B. L., Holst, Jens Juul & Bülow, J., Jul 2019, In: The Journal of clinical endocrinology and metabolism. 104, 7, p. 2509–2519Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Separate and Combined Effects of GIP and GLP-1 Infusions on Bone Metabolism in Overweight Men without Diabetes
Bergmann, N. C., Lund, A., Gasbjerg, Lærke Smidt, Jørgensen, N. R., Jessen, L., Hartmann, Bolette, Holst, Jens Juul, Christensen, Mikkel Bring, Vilsbøll, Tina & Knop, Filip Krag, Jul 2019, In: The Journal of clinical endocrinology and metabolism. 104, 7, p. 2953–2960Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of Calcium, Magnesium, and Potassium Concentrations on Ventricular Repolarization in Unselected Individuals
et al., E. A. & Warren, H. R., 25 Jun 2019, In: Journal of the American College of Cardiology. 73, 24, p. 3118-3131Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DBDS Genomic Cohort, a prospective and comprehensive resource for integrative and temporal analysis of genetic, environmental and lifestyle factors affecting health of blood donors
Hansen, T. F., Banasik, K., Erikstrup, C., Pedersen, O. B., Westergaard, D., Chmura, P. J., Nielsen, K., Thørner, L., Hjalgrim, H., Paarup, H., Larsen, M. A. H., Petersen, M., Jennum, P., Andersen, S., Nyegaard, M., Jemec, G. B. E., Olesen, J., Werge, T., Johansson, P. I., Sørensen, E. & 3 others, , 9 Jun 2019, In: BMJ Open. 9, 6, p. 1-7 7 p., e028401.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Urinary nucleic acid oxidation product levels show differential associations with pharmacological treatment in patients with type 2 diabetes
Kjaer, L. K., Cejvanovic, V., Henriksen, T., Hansen, Torben, Pedersen, Oluf Borbye, Christensen, C. K., Torp-Pedersen, C., Gerds, Thomas Alexander, Brandslund, I., Mandrup-Poulsen, Thomas & Poulsen, Henrik Enghusen, 3 Jun 2019, In: Free Radical Research. 53, 6, p. 694-703Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls
Broad Genomics Platform, B. G. P., Jun 2019, In: Nature. 570, 7759, p. 71-76 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GIP-induced vasodilation in human adipose tissue involves capillary recruitment
Asmar, M., Asmar, A., Simonsen, L., Dela, Flemming, Holst, Jens Juul & Bulow, J., Jun 2019, In: Endocrine Connections. 8, 6, p. 806-813Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bio art and the end of philosophy (Feuerstein & Hegel)
Grünfeld, Martin, 21 May 2019, 1 p.Research output: Other contribution › Net publication - Internet publication › Research › peer-review
- Published
Important Endpoints and Proliferative Markers to Assess Small Intestinal Injury and Adaptation using a Mouse Model of Chemotherapy-Induced Mucositis
Billeschou, Anna, Dal, Jenna Elizabeth Hunt & Kissow, Hannelouise, 12 May 2019, In: Journal of visualized experiments : JoVE. 147, e59236.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dietary Fiber is Essential to Maintain L Cell Secretion and Intestinal Weight
Dal, Jenna Elizabeth Hunt, Hartmann, Bolette, Holst, Jens Juul & Kissow, Hannelouise, 1 May 2019, In: Gastroenterology. 156, 6 (S1), p. S-477Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Gut hormone release after gastric bypass depends on the length of the biliopancreatic limb
Patrício, B. G., Morais, T., Guimarães, M., Veedfald, Simon, Hartmann, Bolette, Hilsted, Linda, Holst, Jens Juul, Nora, M. & Monteiro, M. P., 1 May 2019, In: International Journal of Obesity. 43, 5, p. 1009-1018Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intestinal Growth in Glucagon Receptor Knockout Mice is Not Associated with the Formation of Aom/DSS-Induced Tumours
Dal, Jenna Elizabeth Hunt, Yassin, M., Olsen, Jørgen, Windeløv, Johanne Agerlin, Galsgaard, Katrine Douglas, Holst, Jens Juul & Kissow, Hannelouise, 1 May 2019, In: Gastroenterology. 156, 6 (S1), 1 p., S-692.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Differential action of TGR5 agonists on GLP-2 secretion and promotion of intestinal adaptation in a piglet short bowel model
Lin, S., Stoll, B., Robinson, J., Pastor, J. J., Marini, J. C., Ipharraguerre, I. R., Hartmann, Bolette, Holst, Jens Juul, Cruz, S., Lau, P., Olutoye, O., Fang, Z. & Burrin, D. G., May 2019, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 316, 5, p. G641-G652Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Disease Progression and Pharmacological Intervention in a Nutrient-Deficient Rat Model of Nonalcoholic Steatohepatitis
Tolbol, K. S., Stierstorfer, B., Rippmann, J. F., Veidal, S. S., Rigbolt, K. T. G., Schoenberger, T., Gillum, M. P., Hansen, H. H., Vrang, N., Jelsing, J., Feigh, M. & Broermann, A., May 2019, In: Digestive Diseases and Sciences. 64, 5, p. 1238-1256Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association study identifies 30 loci associated with bipolar disorder
eQTLGen Consortium, E. C., May 2019, In: Nature Genetics. 51, 5, p. 793-803Research output: Contribution to journal › Journal article › Research › peer-review
- Published
FoxK1 and FoxK2 in insulin regulation of cellular and mitochondrial metabolism
Sakaguchi, M., Cai, W., Wang, C., Cederquist, C. T., Damasio, M., Homan, E. P., Batista, T., Ramirez, A. K., Gupta, M. K., Steger, M., Albrechtsen, Nicolai Jacob Wewer, Singh, S. K., Araki, E., Mann, M., Enerbäck, S. & Kahn, C. R., 5 Apr 2019, In: Nature Communications. 10, 1, 17 p., 1582.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular dynamics-guided discovery of an ago-allosteric modulator for GPR40/FFAR1
Lückmann, Michael, Trauelsen, Mette, Bentsen, M. A., Nissen, T. A. D., Martins, J., Fallah, Z., Nygaard, M. M., Papaleo, E., Lindorff-Larsen, Kresten, Schwartz, Thue W. & Frimurer, Thomas Michael, 2 Apr 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 14, p. 7123-7128Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids
Bentley, A. R., Sung, Y. J., Brown, M. R., Winkler, T. W., Kraja, A. T., Ntalla, I., Schwander, K., Chasman, D. I., Lim, E., Deng, X., Guo, X., Liu, J., Lu, Y., Cheng, C-Y., Sim, X., Vojinovic, D., Huffman, J. E., Musani, S. K., Li, C., Feitosa, M. F. & 32 others, , Apr 2019, In: Nature Genetics. 51, 4, p. 636-648 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Peptone-mediated glucagon-like peptide-1 secretion depends on intestinal absorption and activation of basolaterally located Calcium-Sensing Receptors
Modvig, Ida Marie, Kuhre, Rune Ehrenreich & Holst, Jens Juul, Apr 2019, In: Physiological Reports. 7, 8, 13 p., e14056.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A genome-wide association study of shared risk across psychiatric disorders implicates gene regulation during fetal neurodevelopment
Schork, A. J., Won, H., Appadurai, V., Nudel, R., Gandal, M., Delaneau, O., Revsbech Christiansen, M., Hougaard, D. M., Bækved-Hansen, M., Bybjerg-Grauholm, J., Giørtz Pedersen, M., Agerbo, E., Bøcker Pedersen, C., Neale, B. M., Daly, M. J., Wray, N. R., Nordentoft, M., Mors, O., Børglum, A. D., Bo Mortensen, P. & 4 others, , Mar 2019, In: Nature Neuroscience. 22, 3, p. 353-361Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Microbial fermentation of flaxseed fibers modulates the transcriptome of GPR41-expressing enteroendocrine cells and protects mice against diet-induced obesity
Arora, Tulika, Rudenko, Olga, Egerod, Kristoffer Lihme, Husted, Anna Sofie, Kovatcheva-Datchary, P., Akrami, R., Kristensen, M., Schwartz, Thue W. & Backhed, F., Mar 2019, In: American Journal of Physiology: Endocrinology and Metabolism. 316, 3, p. E453-E463Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of DPP-4-protected GLP-1 (7-36) on coronary microvascular function in obese adults
Nilsson, M., Bové, K. B., Suhrs, E., Hermann, T., Madsbad, Sten, Holst, Jens Juul, Prescott, Eva & Zander, M., Mar 2019, In: IJC Heart and Vasculature. 22, p. 139-144Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chronic high dose P2X7 receptor inhibition exacerbates cancer-induced bone pain
Falk, S., Appel, C. K., Bennedbæk, H. B., Al-Dihaissy, T., Unger, A., Dinkel, K. & Heegaard, Anne-Marie, 15 Feb 2019, In: European Journal of Pharmacology. 845, p. 48-55 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of glucagon-like peptide 1 analogs on alcohol intake in alcohol-preferring vervet monkeys
Thomsen, M., Holst, Jens Juul, Molander, A., Linnet, Kristian, Ptito, M. & Fink-Jensen, Anders, Feb 2019, In: Psychopharmacology. 236, 2, p. 603–611Research output: Contribution to journal › Journal article › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity
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Determinants of plasma levels of proglucagon and the metabolic impact of glucagon receptor signalling: a UK Biobank study
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