- 2022
- Published
The GDF15-GFRAL pathway is dispensable for the effects of metformin on energy balance
Klein, A. B., Nicolaisen, T. S., Johann, K., Fritzen, Andreas Mæchel, Mathiesen, C. V., Gil, Cláudia, Pilmark, N. S., Karstoft, Kristian, Blond, Martin Bæk, Quist, Jonas Salling, Seeley, R. J., Færch, K., Lund, Jens, Kleinert, Maximilian & Clemmensen, Christoffer, 2022, In: Cell Reports. 40, 8, 111258.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Glucagon Receptor Antagonist LY2409021 has No Effect on Postprandial Glucose in Type 2 Diabetes
Hædersdal, S., Lund, A., Maagensen, H., Nielsen-Hannerup, E., Gasbjerg, Lærke Smidt, Rosenkilde, Mette, Forman, Julie Lyng, van Hall, Gerrit, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2022, In: European Journal of Endocrinology. 186, 2, p. 207-221 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Greenland population health survey 2018 - methods of a prospective study of risk factors for lifestyle related diseases and social determinants of health amongst Inuit
Bjerregaard, P., Larsen, C. V. L., Olesen, I., Ottendahl, C. B., Backer, Vibeke, Senftleber, N., Christensen, M. M. B., Larsen, T. J., Byberg, S., Hansen, Torben & Jørgensen, M. E., 2022, In: International Journal of Circumpolar Health. 81, 1, 11 p., 2090067.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Liver-Alpha Cell Axis in Health and in Disease
Richter, Michael Martin, Galsgaard, Katrine Douglas, Elmelund, E., Knop, Filip Krag, Suppli, M. P., Holst, Jens Juul, Winther-Sørensen, Marie, Kjeldsen, Sasha Alexandra Sampson & Albrechtsen, Nicolai Jacob Wewer, 2022, In: Diabetes. 71, +, p. 1852–1861Research output: Contribution to journal › Review › Research › peer-review
- Published
The Location of Missense Variants in the Human GIP Gene Is Indicative for Natural Selection
Lindquist, Peter, Gasbjerg, Lærke Smidt, Mokrosinski, J., Holst, Jens Juul, Hauser, Alexander Sebastian & Rosenkilde, Mette, 2022, In: Frontiers in Endocrinology. 13, 14 p., 891586.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Many Faces of Gaia’s Response-ability: A Field Trip to the Critical Zones Digital Platform
Formosinho, Joana, 2022, In: Museums Worlds: Advances in Research. 10, p. 181-192 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Metabolic Role and Therapeutic Potential of the Microbiome
Olofsson, L. E. & Backhed, F., 2022, In: Endocrine Reviews. 43, p. 907-926Research output: Contribution to journal › Review › Research › peer-review
- Published
The Role of D-allulose and Erythritol on the Activity of the Gut Sweet Taste Receptor and Gastrointestinal Satiation Hormone Release in Humans: A Randomized, Controlled Trial
Teysseire, F., Bordier, V., Budzinska, A., Weltens, N., Rehfeld, Jens Frederik, Holst, Jens Juul, Hartmann, Bolette, Beglinger, C., Van Oudenhove, L., Wölnerhanssen, B. K. & Meyer-Gerspach, A. C., 2022, In: Journal of Nutrition. 152, 5, p. 1228–1238,Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Sensory Mechanisms of Nutrient-Induced GLP-1 Secretion
Hjørne, A. P., Modvig, Ida Marie & Holst, Jens Juul, 2022, In: Metabolites. 12, 5, 15 p., 420.Research output: Contribution to journal › Review › Research › peer-review
- Published
The Value of Rare Genetic Variation in the Prediction of Common Obesity in European Ancestry Populations
Wang, Z., Choi, S. W., Chami, N., Boerwinkle, E., Fornage, M., Redline, S., Bis, J. C., Brody, J. A., Psaty, B. M., Kim, W., McDonald, M. L. N., Regan, E. A., Silverman, E. K., Liu, C. T., Vasan, R. S., Kalyani, R. R., Mathias, R. A., Yanek, L. R., Arnett, D. K., Justice, A. E. & 21 others, , 2022, In: Frontiers in Endocrinology. 13, 12 p., 863893.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The developing airway and gut microbiota in early life is influenced by age of older siblings
Christensen, E. D., Hjelmsø, M. H., Thorsen, Jonathan Jan Ilve, Shah, S., Redgwell, T., Poulsen, Christina Egeø, Trivedi, Urvish, Russel, J., Gupta, S., Chawes, Bo Lund Krogsgaard, Bønnelykke, Klaus, Sørensen, Søren Johannes, Rasmussen, Morten Arendt, Bisgaard, H. & Stokholm, Jakob, 2022, In: Microbiome. 10, 15 p., 106.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The developing infant gut microbiome: A strain-level view
Enav, H., Bäckhed, F. & Ley, R. E., 2022, In: Cell Host and Microbe. 30, 5, p. 627-638 12 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
The effect of curcumin on hepatic fat content in individuals with obesity
Hellmann, P. H., Bagger, J. I., Carlander, K. R., Forman, Julie Lyng, Chabanova, E., Svenningsen, J. S., Holst, Jens Juul, Gillum, M. P., Vilsbøll, Tina & Knop, Filip Krag, 2022, In: Diabetes, Obesity and Metabolism. 24, 11, p. 2192-2202 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of gluten in adolescents and young adults with gastrointestinal symptoms: A blinded randomised cross-over trial
Crawley, C., Savino, N., Halby, C., Sander, S. D., Nybo Andersen, Anne-Marie, Arumugam, Mani, Murray, J., Christensen, R. & Husby, S., 2022, In: Alimentary Pharmacology and Therapeutics, Supplement. 55, 9, p. 1116-1127 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effects of laparoscopic Roux-en-Y gastric bypass and one-anastomosis gastric bypass on glycemic control and remission of type 2 diabetes mellitus: study protocol for a multi-center randomized controlled trial (the DIABAR-trial)
van Rijswijk, A., van Olst, N., Meijnikman, A. S., Acherman, Y. I. Z., Bruin, S. C., van de Laar, A. W., van Olden, C. C., Aydin, O., Borger, H., Beuers, U. H. W., Herrema, H., Verheij, J., Apers, J. A., Bäckhed, F., Gerdes, V. E. A., Nieuwdorp, M. & de Brauw, L. M., 2022, In: Trials. 23, 12 p., 900.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The energy balance model of obesity: beyond calories in, calories out
Hall, K. D., Farooqi, I. S., Friedman, J. M., Klein, S., Loos, Ruth, Mangelsdorf, D. J., O'Rahilly, S., Ravussin, E., Redman, L. M., Ryan, D. H., Speakman, J. R. & Tobias, D. K., 2022, In: American Journal of Clinical Nutrition. 115, 5, p. 1243-1254 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The glucagon receptor antagonist LY2409021 does not affect gastrointestinal-mediated glucose disposal or the incretin effect in individuals with and without type 2 diabetes
Hædersdal, S., Lund, A., Nielsen-Hannerup, E., Maagensen, H., Forman, Julie Lyng, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2022, In: European Journal of Endocrinology. 187, 4, p. 507-518 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The human batokine EPDR1 regulates β-cell metabolism and function
Cataldo Bascunan, Luis Rodrigo, Gao, Q., Argemi Muntadas, Lidia, Hodek, O., Cowan, E., Hladkou, S., Gheibi, S., Spegel, P., Prasad, R. B., Eliasson, L., Schéele, Camilla Charlotte Nielsen, Fex, M., Mulder, H. & Moritz, Thomas, 2022, In: Molecular Metabolism. 66, 14 p., 101629.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The impact of anorexia nervosa and BMI polygenic risk on childhood growth: A 20-year longitudinal population-based study
Abdulkadir, M., Hübel, C., Herle, M., Loos, Ruth, Breen, G., Bulik, C. M. & Micali, N., 2022, In: American Journal of Human Genetics. 109, 7, p. 1242-1254 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The incretin/glucagon system as a target for pharmacotherapy of obesity
Del Prato, S., Gallwitz, B., Holst, Jens Juul & Meier, J. J., 2022, In: Obesity Reviews. 23, 2, 13 p., e13372.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The new donor vigilance system in Denmark reveals regional differences in adverse reactions supposedly caused by variation in the registration
Mikkelsen, Christina, Paarup, H. M., Bruun, M. T., Pedersen, L. Ø., Hasslund, S., Larsen, R., Aagaard, B. & Sørensen, B. S., 2022, In: Vox Sanguinis. 117, 3, p. 321-327Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The phosphorylation of AMPKβ1 is critical for increasing autophagy and maintaining mitochondrial homeostasis in response to fatty acids
Desjardins, E. M., Smith, B. K., Day, E. A., Ducommun, S., Sanders, M. J., Nederveen, J. P., Ford, R. J., Pinkosky, S. L., Townsend, L. K., Gutgesell, R. M., Lu, R., Sakamoto, Kei & Steinberg, G. R., 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 48, 8 p., e2119824119.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The physiology of experimental overfeeding in animals
Ranea-Robles, Pablo, Lund, Jens & Clemmensen, Christoffer, 2022, In: Molecular Metabolism. 64, 15 p., 101573.Research output: Contribution to journal › Review › Research › peer-review
- Published
The physiology of obesity: from mechanisms to medicine (M2M). Part one
Lewis, J. E. & Aldiss, Peter Stuart Jacob, 2022, In: Journal of Physiology. 600, 4, p. 697-698 2 p.Research output: Contribution to journal › Editorial › Research
- Published
The physiology of obesity; from mechanisms to medicine. Part two
Aldiss, Peter Stuart Jacob & Lewis, J. E., 2022, In: Journal of Physiology. 600, 5, p. 999-1000 2 p.Research output: Contribution to journal › Editorial › Research
- Published
The proteomic profile of the human myotendinous junction
Karlsen, Anders, Gonzalez-Franquesa, A., Jakobsen, J. R., Krogsgaard, Michael R., Koch, M., Kjær, Michael, Schiaffino, S., Mackey, Abigail & Deshmukh, Atul Shahaji, 2022, In: iScience. 25, 2, 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Thermosensation in Caenorhabditis elegans is linked to ubiquitin-dependent protein turnover via insulin and calcineurin signalling
Segref, A., Vakkayil, K. L., Padvitski, T., Li, Q., Kroef, V., Lormann, J., Körner, L., Finger, Fabian Michael & Hoppe, T., 2022, In: Nature Communications. 13, 1, 17 p., 5874.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Thyrotropin-releasing hormone induces Ca2+ increase in a subset of vagal nodose ganglion neurons
Mamedova, Esmira, Dmytriyeva, O. & Rekling, Jens Christian, 2022, In: Neuropeptides. 94, 9 p., 102261.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tolerable Duration of Warm Ischaemia After Circulatory Death Is Safe For At Least One Hour in Porcine Lungs: Functional Assessment with Ex Vivo Lung Perfusion
Hebsgaard, M. M. B., Kissow, Hannelouise, Lilleør, N. B., Lorenzen, U. S., Chemtob, R. A., Møller-Sørensen, H., Olsen, P. S. & Møller, Christian H., 2022, In: Heart Surgery Forum. 25, 1, p. E48-E52 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transforming growth factor β1 impairs the transcriptomic response to contraction in myotubes from women with polycystic ovary syndrome
McIlvenna, L. C., Altıntaş, Ali, Patten, R. K., McAinch, A. J., Rodgers, R. J., Stepto, N. K., Barrès, Romain & Moreno-Asso, A., 2022, In: The Journal of Physiology. 600, 14, p. 3313-3330Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Type 2 diabetes classification: a data-driven cluster study of the Danish Centre for Strategic Research in Type 2 Diabetes (DD2) cohort
Christensen, D. H., Nicolaisen, S. K., Ahlqvist, E., Stidsen, J. V., Nielsen, J. S., Hojlund, K., Olsen, M. H., García-Calzón, S., Ling, C., Rungby, Jørgen, Brandslund, I., Vestergaard, P., Jessen, N., Hansen, Torben, Brøns, C., Beck-Nielsen, H., Sørensen, H. T., Thomsen, R. W. & Vaag, Allan, 2022, In: B M J Open Diabetes Research & Care. 10, 2, 12 p., e002731.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Type 2 diabetes is associated with increased circulating levels of 3-hydroxydecanoate activating GPR84 and neutrophil migration
Mikkelsen, R. B., Arora, Tulika, Trošt, K., Dmytriyeva, O., Jensen, Sune K. , Meijnikman, A. S., Olofsson, L. E., Lappa, D., Aydin, Ö., Nielsen, J., Gerdes, V., Moritz, Thomas, van de Laar, A., de Brauw, M., Nieuwdorp, M., Hjorth, Siv Annegrethe, Schwartz, Thue W. & Bäckhed, F., 2022, In: iScience. 25, 12, 29 p., 105683.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Vagal afferent cholecystokinin receptor activation is required for glucagon-like peptide-1–induced satiation
Vana, V., Lærke, M. K., Rehfeld, Jens Frederik, Arnold, M., Dmytriyeva, O., Langhans, W., Schwartz, Thue W. & Hansen, Harald S., 2022, In: Diabetes, Obesity and Metabolism. 24, 2, p. 268-280Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Vitamin D Supplementation Improves Fasting Insulin Levels and HDL Cholesterol in Infertile Men
Holt, R., Petersen, Jørgen Holm, Dinsdale, E., Knop, Filip Krag, Juul, Anders, Jørgensen, N. & Jensen, M. B., 2022, In: Journal of Clinical Endocrinology & Metabolism. 107, 1, p. 98-108Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Weight loss improves β-cell function independently of dietary carbohydrate restriction in people with type 2 diabetes: A 6-week randomized controlled trial
Thomsen, M. N., Skytte, M. J., Samkani, A., Astrup, A., Fenger, M., Frystyk, J., Hartmann, Bolette, Holst, Jens Juul, Larsen, T. M., Madsbad, Sten, Magkos, Faidon, Rehfeld, Jens Frederik, Haugaard, Steen Bendix & Krarup, T., 2022, In: Frontiers in Nutrition. 9, 14 p., 933118.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Weight-loss induced by carbohydrate restriction does not negatively affect health-related quality of life and cognition in people with type 2 diabetes: A randomised controlled trial
Jensen, N. J., Wodschow, H. Z., Skytte, M. J., Samkani, A., Astrup, A., Frystyk, J., Hartmann, Bolette, Holst, Jens Juul, Larsen, T. M., Madsbad, Sten, Magkos, Faidon, Miskowiak, Kamilla, Haugaard, Steen Bendix, Krarup, T., Rungby, Jørgen & Thomsen, M. N., 2022, In: Clinical Nutrition. 41, 7, p. 1605-1612 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Whole genome sequence analysis of blood lipid levels in >66,000 individuals
Selvaraj, M. S., Li, X., Li, Z., Pampana, A., Zhang, D. Y., Park, J., Aslibekyan, S., Bis, J. C., Brody, J. A., Cade, B. E., Chuang, L. M., Chung, R. H., Curran, J. E., de las Fuentes, L., de Vries, P. S., Duggirala, R., Freedman, B. I., Graff, M., Guo, X., Heard-Costa, N. & 27 others, , 2022, In: Nature Communications. 13, 18 p., 5995.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Whole genome sequencing identifies structural variants contributing to hematologic traits in the NHLBI TOPMed program
Wheeler, M. M., Stilp, A. M., Rao, S., Halldórsson, B. V., Beyter, D., Wen, J., Mihkaylova, A. V., McHugh, C. P., Lane, J., Jiang, M. Z., Raffield, L. M., Jun, G., Sedlazeck, F. J., Metcalf, G., Yao, Y., Bis, J. B., Chami, N., de Vries, P. S., Desai, P., Floyd, J. S. & 39 others, , 2022, In: Nature Communications. 13, 18 p., 7592.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
With obesity becoming the new normal, what should we do? Volume II
Tziomalos, K., Kilpeläinen, Tuomas O. & Samaras, K., 2022, In: Frontiers in Endocrinology. 13, 3 p., 1119910.Research output: Contribution to journal › Editorial › Research
- Published
Worsening Postural Tachycardia Syndrome Is Associated With Increased Glucose-Dependent Insulinotropic Polypeptide Secretion
Breier, N. C., Paranjape, S. Y., Scudder, S., Mehr, S. E., Diedrich, A., Flynn, C. R., Okamoto, L. E., Hartmann, Bolette, Gasbjerg, Lærke Smidt & Shibao, C. A., 2022, In: Hypertension. 79, 5, p. e89-e99Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ZAKβ is activated by cellular compression and mediates contraction-induced MAP kinase signaling in skeletal muscle
Nordgaard, C., Vind, A. C., Stonadge, A., Kjøbsted, R., Snieckute, G., Antas, P., Blasius, M., Reinert, M. S., Del Val, A. M., Bekker-Jensen, D. B., Haahr, P., Miroshnikova, Y. A., Mazouzi, A., Falk, S., Perrier-Groult, E., Tiedje, C., Li, X., Jakobsen, J. R., Jørgensen, N. O., Wojtaszewski, J. & 12 others, , 2022, In: E M B O Journal. 41, 17, 19 p., e111650.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Zeitgebers of skeletal muscle and implications for metabolic health
Gabriel, B. M. & Zierath, Juleen R, 2022, In: Journal of Physiology. 600, 5, p. 1027-1036Research output: Contribution to journal › Journal article › Research › peer-review
- Published
microRNA-based signatures obtained from endometrial fluid identify implantative endometrium
Ibañez-Perez, J., Díaz-Nuñez, M., Clos-García, M., Lainz, L., Iglesias, M., Díez-Zapirain, M., Rabanal, A., Bárcena, L., González, M., Lozano, J. J., Marigorta, U. M., González, E., Royo, F., Aransay, A. M., Subiran, N., Matorras, R. & Falcón-Pérez, J. M., 2022, In: Human Reproduction. 37, 10, p. 2375-2391 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Editorial: Proglucagon-Derived Peptides
Flatt, P. R., Knop, Filip Krag & Tarasov, A. I., Nov 2021, In: Frontiers in Endocrinology. 12, 776871.Research output: Contribution to journal › Editorial › Research
- Published
Museum as Academy: Research Practices at Copenhagen’s Medical Museion
Arnold, Ken, Bencard, Adam, Tybjerg, Karin & Whiteley, Louise, 24 Sep 2021, In: The Garage Journal: Studies in Art, Museums & Culture. 3, p. 52 81 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Authors’ Reply to Letter to the Editor: Continued improvement to genetic diversity indicator for CBD
Laikre, L., Hohenlohe, P. A., Allendorf, F. W., Bertola, L. D., Breed, M. F., Bruford, M. W., Funk, W. C., Gajardo, G., González-Rodríguez, A., Grueber, C. E., Hedrick, P. W., Heuertz, M., Hunter, M. E., Johannesson, K., Liggins, L., MacDonald, A. J., Mergeay, J., Moharrek, F., O’Brien, D., Ogden, R. & 11 others, , Aug 2021, In: Conservation Genetics. 22, 4, p. 533-536 4 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Hepatic microbiome in healthy lean and obese humans
Suppli, M. P., Bagger, J. I., Lelouvier, B., Broha, A., Demant, M., Kønig, M. J., Strandberg, C., Lund, A., Vilsbøll, Tina & Knop, Filip Krag, Aug 2021, In: JHEP Reports. 3, 4, 100299.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Healthy Weight Loss Maintenance with Exercise, Liraglutide, or Both Combined
Lundgren, J. R., Janus, C., Jensen, Simon Birk Kjær, Juhl, C. R., Olsen, L. M., Christensen, R. M., Svane, M. S., Bandholm, Thomas Quaade, Bojsen-Møller, K. N., Blond, Martin Bæk, Jensen, Jens-Erik Beck, Stallknecht, Bente Merete, Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, 6 May 2021, In: New England Journal of Medicine. 384, p. 1719-1730 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TFEB deficiency attenuates mitochondrial degradation upon brown adipose tissue whitening at thermoneutrality
Sass, Frederike, Schlein, C., Jaeckstein, M. Y., Pertzborn, P., Schweizer, M., Schinke, T., Ballabio, A., Scheja, L., Heeren, J. & Fischer, A. W., 1 May 2021, In: Molecular Metabolism. 47, 19 p., 101173.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Maternal obesity and metabolic disorders associate with congenital heart defects in the offspring: A systematic review
Hedermann, G., Hedley, P. L., Thagaard, I. N., Krebs, Lone, Ekelund, Charlotte Kvist, Sørensen, Thorkild I.A. & Christiansen, M., May 2021, In: PLoS ONE. 16, 5 , 22 p., e0252343.Research output: Contribution to journal › Review › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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The isoenzyme pattern of LDH does not play a physiological role; except perhaps during fast transitions in energy metabolism
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Determinants of plasma levels of proglucagon and the metabolic impact of glucagon receptor signalling: a UK Biobank study
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The interplay between birth weight and obesity in determining childhood and adolescent cardiometabolic risk
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Targeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment
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