Novo Nordisk Foundation Center for Basic Metabolic Research

  1. 2010
  2. Published

    Sustained glucagon-like peptide-2 infusion is required for intestinal adaptation, and cessation reverses increased cellularity in rats with intestinal failure

    Koopmann, M. C., Chen, X., Holst, Jens Juul & Ney, D. M., 1 Dec 2010, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 299, 6, p. G1222-30 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    The levelling off of the obesity epidemic since the year 1999--a review of evidence and perspectives

    Rokholm, B., Baker, J. L. & Sørensen, Thorkild I.A., 1 Dec 2010, In: Obesity Reviews. 11, 12, p. 835-46 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Genetics of type 2 diabetes.

    Ahlqvist, E., Ahluwalia, Tarun Veer Singh & Groop, L., 30 Nov 2010, In: Clinical Chemistry.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Neuronal calcium sensor synaptotagmin-9 is not involved in the regulation of glucose homeostasis or insulin secretion

    Gustavsson, N., Wang, X., Wang, Y., Seah, T., Xu, J., Radda, G. K., Südhof, T. C. & Han, W., 9 Nov 2010, In: PLOS ONE. 5, 11, p. e15414

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    A cereal-based evening meal rich in indigestible carbohydrates increases plasma butyrate the next morning

    Nilsson, A. C., Östman, E. M., Knudsen, K. E. B., Holst, Jens Juul & Björck, I. M. E., 1 Nov 2010, In: Journal of Nutrition. 140, 11, p. 1932-6 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

    Speliotes, E. K., Willer, C. J., Berndt, S. I., Monda, K. L., Thorleifsson, G., Jackson, A. U., Allen, H. L., Lindgren, C. M., Luan, J., Mägi, R., Randall, J. C., Vedantam, S., Winkler, T. W., Lu, Q., Workalemahu, T., Heid, I. M., Steinthorsdottir, V., Stringham, H. M., Weedon, M. N., Wheeler, E. & 31 others, Wood, A. R., Ferreira, T., Weyant, R. J., Segrè, A. V., Estrada, K., Liang, L., Nemesh, J., Park, J., Gustafsson, S., Kilpeläinen, Tuomas O., Yang, J., Bouatia-Naji, N., Esko, T., Feitosa, M. F., Kutalik, Z., Mangino, M., Raychaudhuri, S., Scherag, A., Smith, A. V., Welch, R., Zhao, J. H., Aben, K. K., Absher, D. M., Amin, N., Dixon, A. L., Gjesing, A. P., Jørgensen, T., Witte, D. R., Hansen, Torben, Pedersen, Oluf Borbye & MAGIC, M., 1 Nov 2010, In: Nature Genetics. 42, 11, p. 937-48 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Differential incretin effects of GIP and GLP-1 on gastric emptying, appetite, and insulin-glucose homeostasis

    Edholm, T., Degerblad, M., Grybäck, P., Hilsted, Linda, Holst, Jens Juul, Jacobsson, H., Efendic, S., Schmidt, P. T. & Hellström, P. M., 1 Nov 2010, In: Neurogastroenterology and Motility Online. 22, 11, p. 1191-200, e315 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Insulin resistance induced by physical inactivity is associated with multiple transcriptional changes in skeletal muscle in young men

    Alibegovic, A. C., Sonne, M. P., Højbjerre, L., Bork-Jensen, J., Jacobsen, S., Nilsson, E., Faerch, K., Hiscock, N., Mortensen, B., Friedrichsen, M., Stallknecht, Bente Merete, Dela, Flemming & Vaag, Allan, 1 Nov 2010, In: American Journal of Physiology: Endocrinology and Metabolism. 299, 5, p. E752-63 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

    Heid, I. M., Jackson, A. U., Randall, J. C., Winkler, T. W., Qi, L., Steinthorsdottir, V., Thorleifsson, G., Zillikens, M. C., Speliotes, E. K., Mägi, R., Workalemahu, T., White, C. C., Bouatia-Naji, N., Harris, T. B., Berndt, S. I., Ingelsson, E., Willer, C. J., Weedon, M. N., Luan, J., Vedantam, S. & 31 others, Esko, T., Kilpeläinen, Tuomas O., Kutalik, Z., Li, S., Monda, K. L., Dixon, A. L., Holmes, C. C., Kaplan, L. M., Liang, L., Min, J. L., Moffatt, M. F., Molony, C., Nicholson, G., Schadt, E. E., Zondervan, K. T., Feitosa, M. F., Ferreira, T., Allen, H. L., Weyant, R. J., Wheeler, E., Wood, A. R., Estrada, K., Goddard, M. E., Lettre, G., Mangino, M., Gjesing, A. P., Witte, D. R., Hansen, Torben, Jørgensen, T., Pedersen, Oluf Borbye & MAGIC, M., 1 Nov 2010, In: Nature Genetics. 42, 11, p. 949-60 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Overweight and obesity trends in Copenhagen schoolchildren from 2002 to 2007

    Pearson, S., Hansen, B., Sørensen, Thorkild I.A. & Baker, J. L., 1 Nov 2010, In: Acta Paediatrica. 99, 11, p. 1675-8 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Chronic high-fat diet in fathers programs ß-cell dysfunction in female rat offspring

    Ng, S., Lin, R. C. Y., Laybutt, D. R., Barrès, Romain, Owens, J. A. & Morris, M. J., 21 Oct 2010, In: Nature. 467, 7318, p. 963-6 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Kardiale virkninger af glukagonlignende peptid 1

    Holst, Jens Juul, 11 Oct 2010, In: Ugeskrift for Laeger. 172, 41, p. 2821 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B

    Yamauchi, T., Hara, K., Maeda, S., Yasuda, K., Takahashi, A., Horikoshi, M., Nakamura, M., Fujita, H., Grarup, N., Cauchi, S., Ng, D. P. K., Ma, R. C. W., Tsunoda, T., Kubo, M., Watada, H., Maegawa, H., Okada-Iwabu, M., Iwabu, M., Shojima, N., Shin, H. D. & 26 others, Andersen, G., Witte, D. R., Jørgensen, T., Lauritzen, T., Sandbæk, A., Hansen, T., Ohshige, T., Omori, S., Saito, I., Kaku, K., Hirose, H., So, W., Beury, D., Chan, J. C. N., Park, K. S., Tai, E. S., Ito, C., Tanaka, Y., Kashiwagi, A., Kawamori, R., Kasuga, M., Froguel, P., Pedersen, Oluf Borbye, Kamatani, N., Nakamura, Y. & Kadowaki, T., 1 Oct 2010, In: Nature Genetics. 42, 10, p. 864-8 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Expression of mRNA for proglucagon and glucagon-like peptide-2 (GLP-2) receptor in the ruminant gastrointestinal tract and the influence of energy intake

    Taylor-Edwards, C. C., Burrin, D. G., Matthews, J. C., McLeod, K. R., Holst, Jens Juul & Harmon, D. L., 1 Oct 2010, In: Domestic Animal Endocrinology. 39, 3, p. 181-93 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Revising consensus in portal hypertension: report of the Baveno V consensus workshop on methodology of diagnosis and therapy in portal hypertension

    de Franchis, R., Baveno V Faculty, B. V. F. & Sørensen, Thorkild I.A., 1 Oct 2010, In: Journal of Hepatology. 53, 4, p. 762-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    The intestinotrophic peptide, GLP-2, counteracts the gastrointestinal atrophy in mice induced by the epidermal growth factor receptor inhibitor, erlotinib, and cisplatin

    Rasmussen, A. R., Viby, N., Hare, K. J., Hartmann, Bolette, Thim, L., Holst, Jens Juul & Poulsen, Steen Seier, 1 Oct 2010, In: Digestive Diseases and Sciences. 55, 10, p. 2785-96 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    SmashCell: A software framework for the analysis of single-cell amplified genome sequences.

    Harrington, E. D., Arumugam, Mani, Raes, J., Bork, P. & Relman, D. A., Oct 2010, In: Bioinformatics. 26, 23, p. 2979-2980 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    SmashCommunity: A metagenomic annotation and analysis tool.

    Arumugam, Mani, Harrington, E. D., Foerstner, K. U., Raes, J. & Bork, P., Oct 2010, In: Bioinformatics. 26, 23, p. 2977-2978 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    High body mass index in adolescent girls precedes psoriasis hospitalization

    Bryld, L. E., Sørensen, Thorkild I.A., Andersen, K. K., Jemec, G. & Baker, J. L., 1 Sep 2010, In: Acta Dermato Venereologica. 90, 5, p. 488-93 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Latent autoimmune diabetes in adults differs genetically from classical type 1 diabetes diagnosed after the age of 35 years

    Lepola, Mette Andersen, Lundgren, V., Turunen, J. A., Forsblom, C., Isomaa, B., Groop, P. H., Groop, L. & Tuomi, T., 1 Sep 2010, In: Diabetes Care. 33, 9, p. 2062-2064 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Type 2 diabetes risk alleles near ADCY5, CDKAL1 and HHEX-IDE are associated with reduced birthweight

    Andersson, E. A., Pilgaard, K., Pisinger, C., Harder, M. N., Grarup, N., Faerch, K., Poulsen, P., Witte, D. R., Jørgensen, T., Vaag, Allan, Hansen, Torben & Pedersen, Oluf Borbye, 1 Sep 2010, In: Diabetologia. 53, 9, p. 1908-16 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    A maternal low protein diet has pronounced effects on mitochondrial gene expression in offspring liver and skeletal muscle; protective effect of taurine

    Mortensen, Ole Hartvig, Olsen, H. L., Frandsen, L., Nielsen, Peter E., Nielsen, Finn Cilius, Grunnet, N. & Quistorff, B., 1 Aug 2010, In: Journal of Biomedical Science. 24, 17, p. 1-11

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Effects of erythropoietin administration on cerebral metabolism and exercise capacity in men

    Rasmussen, P., Foged, E. M., Krogh-Madsen, Rikke, Nielsen, Jannie, Nielsen, Thomas Rune, Olsen, N. V., Petersen, Nicolas Caesar, Sørensen, T. A., Secher, Niels H., Lundby, C., Rasmussen, P., Foged, E. M., Krogh-Madsen, R., Nielsen, J., Nielsen, T. R., Olsen, N. V., Petersen, N. C., Sørensen, Thorkild I.A., Secher, Niels H. & Lundby, C., 1 Aug 2010, In: Journal of Applied Physiology. 109, 2, p. 476-83 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm

    Gretarsdottir, S., Baas, A. F., Thorleifsson, G., Holm, H., den Heijer, M., de Vries, J-P. P. M., Kranendonk, S. E., Zeebregts, C. J. A. M., van Sterkenburg, S. M., Geelkerken, R. H., van Rij, A. M., Williams, M. J. A., Boll, A. P. M., Kostic, J. P., Jonasdottir, A., Jonasdottir, A., Walters, G. B., Masson, G., Sulem, P., Saemundsdottir, J. & 82 others, Mouy, M., Magnusson, K. P., Tromp, G., Elmore, J. R., Sakalihasan, N., Limet, R., Defraigne, J., Ferrell, R. E., Ronkainen, A., Ruigrok, Y. M., Wijmenga, C., Grobbee, D. E., Shah, S. H., Granger, C. B., Quyyumi, A. A., Vaccarino, V., Patel, R. S., Zafari, A. M., Levey, A. I., Austin, H., Girelli, D., Pignatti, P. F., Olivieri, O., Martinelli, N., Malerba, G., Trabetti, E., Becker, L. C., Becker, D. M., Reilly, M. P., Rader, D. J., Mueller, T., Dieplinger, B., Haltmayer, M., Urbonavicius, S., Lindblad, B., Gottsäter, A., Gaetani, E., Pola, R., Wells, P., Rodger, M., Forgie, M., Langlois, N., Corral, J., Vasquez, V., Fontcuberta, J., España, F., Grarup, N., Jørgensen, T., Witte, D. R., Hansen, Torben, Pedersen, Oluf Borbye, Aben, K. K., de Graaf, J., Holewijn, S., Folkersen, L., Franco-Cereceda, A., Eriksson, P., Collier, D. A., Stefansson, H., Steinthorsdottir, V., Rafnar, T., Valdimarsson, E. M., Magnadottir, H. B., Sveinbjornsdottir, S., Olafsson, I., Magnusson, M. K., Palmason, R., Haraldsdottir, V., Andersen, K., Onundarson, P. T., Thorgeirsson, G., Kiemeney, L. A., Powell, J. T., Carey, D. J., Kuivaniemi, H., Lindholt, J. S., Jones, G. T., Kong, A., Blankensteijn, J. D., Matthiasson, S. E., Thorsteinsdottir, U. & Stefansson, K., 1 Aug 2010, In: Nature Genetics. 42, 8, p. 692-7 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Influence of lifestyle aspects on the association of body size and shape with all-cause mortality in middle-aged men and women

    Bigaard, J., Christensen, J., Tjønneland, A., Thomsen, B. L. R., Overvad, K. & Sørensen, Thorkild I.A., 1 Aug 2010, In: Obesity Facts. 3, 4, p. 252-60 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review