Novo Nordisk Foundation Center for Basic Metabolic Research

  1. 2010
  2. Published

    Impact of rs361072 in the phosphoinositide 3-kinase p110beta gene on whole-body glucose metabolism and subunit protein expression in skeletal muscle

    Ribel-Madsen, R., Poulsen, P., Holmkvist, J., Mortensen, B., Grarup, N., Friedrichsen, M., Jørgensen, T., Lauritzen, T., Wojtaszewski, Jørgen F P, Pedersen, Oluf Borbye, Hansen, Torben & Vaag, Allan, 2010, In: Diabetes. 59, 4, p. 1108-1112 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Impact of size at birth and prematurity on adult anthropometry in 4744 middle-aged Danes - The Inter99 Study

    Pilgaard, K., Færch, K., Poulsen, P., Larsen, C., Andersson, E. A., Pisinger, C. H., Toft, U., Aadahl, M., Pedersen, Oluf Borbye, Hansen, Torben, Jørgensen, T., Borch-Johnsen, K. & Vaag, Allan, 2010, In: Journal of Developmental Origins of Health and Disease. 1, 5, p. 319-328 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    MTNR1B G24E variant associates With BMI and fasting plasma glucose in the general population in studies of 22,142 Europeans

    Andersson, E. A., Holst, Birgitte, Sparsø, T., Grarup, N., Banasik, Karina, Holmkvist, J., Jørgensen, T., Borch-Johnsen, K., Egerod, Kristoffer Lihme, Lauritzen, T., Sørensen, Thorkild I.A., Bonnefond, A., Meyre, D., Froguel, P., Schwartz, Thue W., Pedersen, Oluf Borbye & Hansen, Torben, 2010, In: Diabetes. 59, 6, p. 1539-48 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Molecular Mechanisms and Genome-Wide Aspects of PPAR Subtype Specific Transactivation

    Bugge, A. S. & Mandrup, S., 2010, In: PPAR Research. 2010

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Neuroscience evidence should be incorporated into our ethical practices

    Felsen, G., Whiteley, Louise, Nadler, R. & Reiner, P. B., 2010, In: A J O B Neuroscience. 1, 4, p. 36-38

    Research output: Contribution to journalComment/debateCommunication

  7. Published

    Obesity-related polymorphisms and their associations with the ability to regulate fat oxidation in obese europeans: The NUGENOB Study

    Corpeleijn, E., Petersen, L., Holst, C., Saris, W. H., Astrup, A., Langin, D., Macdonald, I., Martinez, J. A., Oppert, J., Polak, J., Pedersen, Oluf Borbye, Froguel, P., Arner, P., Sørensen, Thorkild I.A. & Blaak, E. E., 2010, In: Obesity. 18, 7, p. 1369-1377 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants

    Li, Y., Vinckenbosch, N., Tian, G., Huerta-Sanchez, E., Jiang, T., Jiang, H., Albrechtsen, A., Andersen, G., Cao, H., Korneliussen, T. S., Grarup, N., Guo, Y., Hellman, I., Jin, X., Li, Q., Liu, J., Liu, X., Sparsø, T., Tang, M., Wu, H. & 18 others, Wu, R., Yu, C., Zheng, H., Astrup, A., Bolund, L., Holmkvist, J., Jørgensen, T., Kristiansen, Karsten, Schmitz, O., Schwartz, Thue W., Zhang, X., Li, R., Yang, H., Wang, J., Hansen, Torben, Pedersen, Oluf Borbye, Nielsen, Rasmus & Wang, J., 2010, In: Nature Genetics. 42, 11, p. 969-72 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Spatially distributed encoding of covert attentional shifts in human thalamus

    Hulme, O. J., Whiteley, Louise & Shipp, S., 2010, In: Journal of Neurology & Neurophysiology. 104, 6, p. 3644-56 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    The T-allele of TCF7L2 rs7903146 associates with a reduced compensation of insulin secretion for insulin resistance induced by 9 days of bed rest

    Alibegovic, A. C., Sonne, M. P., Højbjerre, L., Hansen, T., Pedersen, Oluf Borbye, van Hall, Gerrit, Holst, Jens Juul, Stallknecht, Bente Merete, Dela, Flemming & Vaag, A., 2010, In: Diabetes. 59, 4, p. 836-43 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    The chemistry of life: Four chapters in the history of metabolic research

    Bencard, Adam, 2010

    Research output: Non-textual form2D/3D (psysical products)Communication

  12. 2009
  13. Published

    Role of the AMPKgamma3 isoform in hypoxia-stimulated glucose transport in glycolytic skeletal muscle

    Deshmukh, Atul Shahaji, Glund, S., Tom, R. Z. & Zierath, Juleen R, Dec 2009, In: American Journal of Physiology: Endocrinology and Metabolism. 297, 6, p. E1388-94

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    ZBED6, a novel transcription factor derived from a domesticated DNA transposon regulates IGF2 expression and muscle growth

    Markljung, E., Jiang, L., Jaffe, J. D., Mikkelsen, T. S., Wallerman, O., Larhammar, M., Zhang, X., Wang, L., Saenz-Vash, V., Gnirke, A., Lindroth, A. M., Barres, R., Yan, J., Strömberg, S., De, S., Pontén, F., Lander, E. S., Carr, S. A., Zierath, J. R., Kullander, K. & 5 others, Wadelius, C., Lindblad-Toh, K., Andersson, G., Hjälm, G. & Andersson, L., Dec 2009, In: P L o S Biology (Online). 7, 12, p. e1000256

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Genetic and clinical profile of Indian patients of idiopathic restrictive cardiomyopathy with and without hypertrophy

    Rai, T. S., Ahmad, S., Ahluwalia, Tarun Veer Singh, Ahuja, M., Bahl, A., Saikia, U. N., Singh, B., Talwar, K. K. & Khullar, M., Nov 2009, In: Developments in Molecular and Cellular Biochemistry. 331, 1-2, p. 187-92 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Transcriptome complexity in a genome-reduced bacterium.

    Güell, M., van Noort, V., Yus, E., Chen, W., Leigh-Bell, J., Michalodimitrakis, K., Yamada, T., Arumugam, Mani, Doerks, T., Kühner, S., Rode, M., Suyama, M., Schmidt, S., Gavin, A., Bork, P. & Serrano, L., Nov 2009, In: Science. 326, 5957, p. 1268-1271 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    A variant in the KCNQ1 gene predicts future type 2 diabetes and mediates impaired insulin secretion

    Jonsson, Anna Elisabet, Isomaa, B., Tuomi, T., Taneera, J., Salehi, A., Nilsson, P., Groop, L. & Lyssenko, V., Oct 2009, In: Diabetes. 58, 10, p. 2409-13 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Peroxisome proliferator-activated receptor gamma regulates expression of the anti-lipolytic G-protein-coupled receptor 81 (GPR81/Gpr81)

    Jeninga, E. H., Bugge, A. S., Nielsen, R., Kersten, S., Hamers, N., Dani, C., Wabitsch, M., Berger, R., Stunnenberg, H. G., Mandrup, S. & Kalkhoven, E., 25 Sep 2009, In: The Journal of Biological Chemistry. 284, 39, p. 26385-93 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment

    Schafer, Z. T., Grassian, A. R., Song, L., Jiang, Z., Gerhart-Hines, Zach, Irie, H. Y., Gao, S., Puigserver, P. & Brugge, J. S., 3 Sep 2009, In: Nature. 461, 7260, p. 109-113 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Non-CpG methylation of the PGC-1alpha promoter through DNMT3B controls mitochondrial density

    Barrès, Romain, Osler, M. E., Yan, J., Rune, A., Fritz, T., Caidahl, K., Krook, A. & Zierath, Juleen R, Sep 2009, In: Cell Metabolism. 10, 3, p. 189-98 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Calcium-sensing beyond neurotransmitters: functions of synaptotagmins in neuroendocrine and endocrine secretion

    Gustavsson, N. & Han, W., Aug 2009, In: Bioscience Reports. 29, 4, p. 245-59 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Overweight and the metabolic syndrome in adult offspring of women with diet-treated gestational diabetes mellitus or type 1 diabetes

    Clausen, Tine Dalsgaard, Mathiesen, E. R., Hansen, T., Pedersen, Oluf Borbye, Jensen, D. M., Lauenborg, J., Schmidt, Lone, Damm, Peter, Clausen, T. D., Mathiesen, Elisabeth, Hansen, T., Pedersen, O., Jensen, D., Lauenborg, J., Schmidt, L. & Damm, Peter, 1 Jul 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 7, p. 2464-70 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    The T allele of rs7903146 TCF7L2 is associated with impaired insulinotropic action of incretin hormones, reduced 24 h profiles of plasma insulin and glucagon, and increased hepatic glucose production in young healthy men

    Pilgaard, K., Jensen, C., Schou, J., Lyssenko, V., Wegner, L., Brøns, C., Vilsbøll, T., Hansen, T., Madsbad, S., Holst, J., Vølund, A., Poulsen, P., Groop, L., Pedersen, O., Vaag, A., Pilgaard, K., Jensen, C. B., Schou, J. H., Lyssenko, V., Wegner, L. & 10 others, Brøns, C., Vilsbøll, T., Hansen, T., Madsbad, Sten, Holst, J. M., Vølund, A., Poulsen, P., Groop, L., Pedersen, O. & Vaag, A., 1 Jul 2009, In: Diabetologia. 52, 7, p. 1298-307 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Altered expression and insulin-induced trafficking of Na+-K+-ATPase in rat skeletal muscle: effects of high-fat diet and exercise

    Galuska, D., Kotova, O., Barrès, Romain, Chibalina, D., Benziane, B. & Chibalin, A. V., Jul 2009, In: A J P: Endocrinology and Metabolism (Online). 297, 1, p. E38-49

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Assessing the effect of interaction between an FTO variant (rs9939609) and physical activity on obesity in 15,925 Swedish and 2,511 Finnish adults

    Jonsson, Anna Elisabet, Renström, F., Lyssenko, V., Brito, E. C., Isomaa, B., Berglund, G., Nilsson, P., Groop, L. & Franks, P. W., Jul 2009, In: Diabetologia. 52, 7, p. 1334-8 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Pairagon: a highly accurate, HMM-based cDNA-to-genome aligner.

    Lu, D. V., Brown, R. H., Arumugam, Mani & Brent, M. R., Jul 2009, In: Bioinformatics. 25, 13, p. 1587-1593 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Interaction between prenatal growth and high-risk genotypes in the development of type 2 diabetes

    Pulizzi, N., Lyssenko, V., Jonsson, Anna Elisabet, Osmond, C., Laakso, M., Kajantie, E., Barker, D. J., Groop, L. C. & Eriksson, J. G., May 2009, In: Diabetologia. 52, 5, p. 825-9 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review