Novo Nordisk Foundation Center for Basic Metabolic Research

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  1. 2009
  2. Published

    Obesity, FTO gene variant, and energy intake in children

    Jonsson, Anna Elisabet & Franks, P. W., 9 Apr 2009, In: New England Journal of Medicine. 360, 15, p. 1571-2; author reply 1572

    Research output: Contribution to journal › Journal article › Research

  3. Published

    Synaptotagmin-7 is a principal Ca2+ sensor for Ca2+ -induced glucagon exocytosis in pancreas

    Gustavsson, N., Wei, S., Hoang, D. N., Lao, Y., Zhang, Q., Radda, G. K., Rorsman, P., Südhof, T. C. & Han, W., 15 Mar 2009, In: The Journal of Physiology. 587, Pt 6, p. 1169-78 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    ACE variants interact with the RAS pathway to confer risk and protection against type 2 diabetic nephropathy

    Ahluwalia, Tarun Veer Singh, Ahuja, M., Rai, T. S., Kohli, H. S., Bhansali, A., Sud, K. & Khullar, M., Mar 2009, In: D N A and Cell Biology. 28, 3, p. 141-50 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Concurrent regulation of AMP-activated protein kinase and SIRT1 in mammalian cells

    Suchankova, G., Nelson, L. E., Gerhart-Hines, Zach, Kelly, M., Gauthier, M. S., Saha, A. K., Ido, Y., Puigserver, P. & Ruderman, N. B., 23 Jan 2009, In: Biochemical and Biophysical Research Communications. 378, 4, p. 836-841 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Common type 2 diabetes risk gene variants associate with gestational diabetes

    Lauenborg, J., Grarup, N., Damm, Peter, Borch-Johnsen, K., Jørgensen, T., Pedersen, Oluf Borbye, Hansen, T., Lauenborg, J., Grarup, N., Damm, Peter, Borch-Johnsen, K., Jørgensen, T., Pedersen, O. & Hansen, T., 1 Jan 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 1, p. 145-50 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion

    Lyssenko, V., Nagorny, C. L. F., Erdos, M. R., Wierup, N., Jonsson, A. E., Spégel, P., Bugliani, M., Saxena, R., Fex, M., Pulizzi, N., Isomaa, B., Tuomi, T., Nilsson, P., Kuusisto, J., Tuomilehto, J., Boehnke, M., Altshuler, D., Sundler, F., Eriksson, J. G., Jackson, A. U. & 5 others, Laakso, M., Marchetti, P., Watanabe, R. M., Mulder, H. & Groop, L., Jan 2009, In: Nature Genetics. 41, 1, p. 82-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Genotype phenotype correlations of cardiac beta-myosin heavy chain mutations in Indian patients with hypertrophic and dilated cardiomyopathy

    Rai, T. S., Ahmad, S., Bahl, A., Ahuja, M., Ahluwalia, Tarun Veer Singh, Singh, B., Talwar, K. K. & Khullar, M., Jan 2009, In: Molecular and Celluar Biochemistry. 321, 1-2, p. 189-96 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    A variant in the G6PC2/ABCB11 locus is associated with increased fasting plasma glucose, increased basal hepatic glucose production and increased insulin release after oral and intravenous glucose loads

    Rose, C. S., Grarup, N., Krarup, N. T., Poulsen, P., Wegner, L., Nielsen, T., Banasik, Karina, Faerch, K., Andersen, G., Albrechtsen, Anders, Borch-Johnsen, K., Clausen, J. O., Jørgensen, T., Vaag, Allan, Pedersen, Oluf Borbye & Hansen, Torben, 2009, In: Diabetologia. 52, 10, p. 2122-2129 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk

    Bouatia-Naji, N., Bonnefond, A., Cavalcanti-Proença, C., Sparsø, T., Holmkvist, J., Marchand, M., Delplanque, J., Lobbens, S., Rocheleau, G., Durand, E., De Graeve, F., Chèvre, J-C., Borch-Johnsen, K., Hartikainen, A-L., Ruokonen, A., Tichet, J., Marre, M., Weill, J., Heude, B., Tauber, M. & 21 others, Lemaire, K., Schuit, F., Elliott, P., Jørgensen, T., Charpentier, G., Hadjadj, S., Cauchi, S., Vaxillaire, M., Sladek, R., Visvikis-Siest, S., Balkau, B., Lévy-Marchal, C., Pattou, F., Meyre, D., Blakemore, A. I. F., Jarvelin, M., Walley, A. J., Hansen, Torben, Dina, C., Pedersen, Oluf Borbye & Froguel, P., 2009, In: Nature Genetics. 41, 1, p. 89-94 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Association of polymorphisms of the CHI3L1 gene with asthma and atopy: a populations-based study of 6514 Danish adults

    Rathcke, C. N., Holmkvist, J., Husmoen, L. L. N., Hansen, T., Pedersen, Oluf Borbye, drb459, drb459 & Linneberg, Allan René, 2009, In: PLoS ONE. 4, 7, p. e6106

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Bleeding peptic ulcer. Prevalence of Helicobacter pylori and use of nonsteroidal anti-inflammatory drugs/acetylsalicylic acid

    Vestergard, A., Bredahl, K., Muckadell, O. B. D., Pedersen, Oluf Borbye & Hansen, J. M., 2009, In: Ugeskrift for læger. 171, 4, p. 235-239 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Combined analysis of 19 common validated type 2 diabetes susceptibility gene variants shows moderate discriminative value and no evidence of gene-gene interaction

    Sparsø, T., Grarup, N., Andreasen, C., Albrechtsen, A., Holmkvist, J., Andersen, G., Jørgensen, T., Borch-Johnsen, K., Sandbaek, A., Lauritzen, T., Madsbad, S., Hansen, T., Pedersen, O., Sparsø, T., Grarup, N., Andreasen, C., Albrechtsen, A., Holmkvist, J., Andersen, G., Jørgensen, T. & 6 others, Borch-Johnsen, K., Sandbaek, A., Lauritzen, T., Madsbad, Sten, Hansen, T. & Pedersen, O., 2009, In: Diabetologia. 52, 7, p. 1308-14 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Combining insulin with metformin or an insulin secretagogue in non-obese patients with type 2 diabetes: 12 month, randomised, double blind trial

    Lund, S. S., Tarnow, L., Frandsen, M., Nielsen, B. B., Hansen, B. V., Pedersen, Oluf Borbye, Parving, H. & Vaag, A. A., 2009, In: BMJ. British Medical Journal (International Ed.). 339, p. b4324

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Common variants of inflammatory cytokine genes are associated with risk of nephropathy in type 2 diabetes among Asian Indians.

    Ahluwalia, Tarun Veer Singh, Khullar, M., Ahuja, M., Kohli, H. S., Bhansali, A., Mohan, V., Venkatesan, R., Rai, T. S., Sud, K. & Singal, P. K., 2009, In: PLOS ONE. 4, 4, p. e5168

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Development of a type 2 diabetes risk model from a panel of serum biomarkers from the Inter99 cohort

    Kolberg, J. A., Jørgensen, T., Gerwien, R. W., Hamren, S., McKenna, M. P., Moler, E., Rowe, M. W., Urdea, M. S., Xu, X. M., Hansen, T., Pedersen, Oluf Borbye & Borch-Johnsen, K., 2009, In: Diabetes Care. 32, 7, p. 1207-12 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Diabetes in infants may be treated with sulfonylurea as a replacement for insulin

    Lauridsen, M. H., Boesgaard, T. W., Pedersen, Oluf Borbye, Hansen, T. & Hertz, B., 2009, In: Ugeskrift for læger. 171, 23, p. 1923-1924 1 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Dietary patterns predict changes in two-hour post-oral glucose tolerance test plasma glucose concentrations in middle-aged adults

    Lau, C., Toft, U., Tetens, Inge , Carstensen, Bendix, Jørgensen, T., Pedersen, Oluf Borbye & Borch-Johnsen, K., 2009, In: Journal of Nutrition. 139, 3, p. 588-593 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Fatness-associated FTO gene variant increases mortality independent of fatness--in cohorts of Danish men

    Zimmermann, E., Kring, S. I. I., Berentzen, T. L., Holst, C., Pers, T. H., Hansen, Torben, Pedersen, Oluf Borbye, Sørensen, Thorkild I.A. & Jess, T., 2009, In: PLoS ONE. 4, 2, p. e4428

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Four-month treatment with GLP-2 significantly increases hip BMD: a randomized, placebo-controlled, dose-ranging study in postmenopausal women with low BMD

    Henriksen, D. B., Alexandersen, P., Hartmann, Bolette, Adrian, C. L., Byrjalsen, I., Bone, H. G., Holst, Jens Juul & Christiansen, C., 2009, In: Bone. 45, 5, p. 833-42 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Functional SOCS1 polymorphisms are associated with variation in obesity in whites

    Gylvin, T., Ek, J., Nolsøe, R., Albrechtsen, A., Andersen, G., Bergholdt, R., Brorsson, C., Bang-Berthelsen, C. H., Hansen, T., Karlsen, A. E., Billestrup, N., Borch-Johnsen, K., Jørgensen, T., Pedersen, Oluf Borbye, Mandrup-Poulsen, Thomas, Nerup, J. & Pociot, Flemming, 2009, In: Diabetes, Obesity and Metabolism. 11, 3, p. 196-203 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    G protein-coupled receptor 39 deficiency is associated with pancreatic islet dysfunction

    Holst, Birgitte, Egerod, Kristoffer Lihme, Jin, C., Petersen, P. S., Østergaard, M. V., Hald, J., Sprinkel, A. M. E., Størling, J., Mandrup-Poulsen, Thomas, Holst, Jens Juul, Thams, P., Orskov, C., Wierup, N., Sundler, F., Madsen, O. D. & Schwartz, Thue W., 2009, In: Endocrinology. 150, 6, p. 2577-85 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    G-allele of intronic rs10830963 in MTNR1B confers increased risk of impaired fasting glycemia and type 2 diabetes through an impaired glucose-stimulated insulin release: studies involving 19,605 Europeans

    Sparsø, T., Bonnefond, A., Andersson, E., Bouatia-Naji, N., Holmkvist, J., Wegner, L., Grarup, N., Gjesing, A. P., Banasik, K., Cavalcanti-Proença, C., Marchand, M., Vaxillaire, M., Charpentier, G., Jarvelin, M-R., Tichet, J., Balkau, B., Marre, M., Lévy-Marchal, C., Faerch, K., Borch-Johnsen, K. & 36 others, Jørgensen, T., Madsbad, Sten, Poulsen, P., Vaag, Allan, Dina, C., Hansen, T., Pedersen, Oluf Borbye, Froguel, P., Sparsø, T., Bonnefond, A., Andersson, E., Bouatia-Naji, N., Holmkvist, J., Wegner, L., Grarup, N., Gjesing, A. P., Banasik, K., Cavalcanti-Proença, C., Marchand, M., Vaxillaire, M., Charpentier, G., Jarvelin, M., Tichet, J., Balkau, B., Marre, M., Lévy-Marchal, C., Faerch, K., Borch-Johnsen, K., Jørgensen, T., Madsbad, Sten, Poulsen, P., Vaag, A., Dina, C., Hansen, T., Pedersen, O. & Froguel, P., 2009, In: Diabetes. 58, 6, p. 1450-6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Genetic association analysis of 13 nuclear-encoded mitochondrial candidate genes with type II diabetes mellitus: The DAMAGE study

    Reiling, E., van Vliet-Ostaptchouk, J. V., van 't Riet, E., van Haeften, T. W., Arp, P. A., Hansen, Torben, Kremer, D., Groenewoud, M. J., van Hove, E. C., Romijn, J. A., Smit, J. W. A., Nijpels, G., Heine, R. J., Uitterlinden, A. G., Pedersen, Oluf Borbye, Slagboom, P. E., Maassen, J. A., Hofker, M. H., 't Hart, L. M. & Dekker, J. M., 2009, In: European Journal of Human Genetics. 17, 8, p. 1056-1062 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes

    Perry, J. R. B., Weedon, M. N., Langenberg, C., Jackson, A. U., Lyssenko, V., Sparsø, T., Thorleifsson, G., Grallert, H., Ferrucci, L., Maggio, M., Paolisso, G., Walker, M., Palmer, C. N. A., Payne, F., Young, E., Herder, C., Narisu, N., Morken, M. A., Bonnycastle, L. L., Owen, K. R. & 38 others, Shields, B., Knight, B., Bennett, A., Groves, C. J., Ruokonen, A., Jarvelin, M. R., Pearson, E., Pascoe, L., Ferrannini, E., Bornstein, S. R., Stringham, H. M., Scott, L. J., Kuusisto, J., Nilsson, Carl Martin Peter, Neptin, M., Gjesing, A. P., Pisinger, C., Lauritzen, T., Sandbaek, A., Sampson, M., Zeggini, M. E., Lindgren, C. M., Steinthorsdottir, V., Thorsteinsdottir, U., Hansen, T., Schwarz, Peter, Illig, T., Laakso, M., Stefansson, K., Morris, A. D., Groop, L., Pedersen, Oluf Borbye, Boehnke, M., Barroso, I., Wareham, N. J., Hattersley, A. T., McCarthy, M. I. & Frayling, T. M., 2009, In: Human Molecular Genetics. 19, 3, p. 535-44 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Genetic variant in HK1 is associated with a proanemic state and A1C but not other glycemic control-related traits

    Bonnefond, A., Vaxillaire, M., Labrune, Y., Lecoeur, C., Chèvre, J-C., Bouatia-Naji, N., Cauchi, S., Balkau, B., Marre, M., Tichet, J., Riveline, J-P., Hadjadj, S., Gallois, Y., Czernichow, S., Hercberg, S., Kaakinen, M., Wiesner, S., Charpentier, G., Lévy-Marchal, C., Elliott, P. & 7 others, Jarvelin, M., Horber, F., Dina, C., Pedersen, Oluf Borbye, Sladek, R., Meyre, D. & Froguel, P., 2009, In: Diabetes. 58, 11, p. 2687-97 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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