Novo Nordisk Foundation Center for Basic Metabolic Research

  1. 2008
  2. Published

    Association of variants in the sterol regulatory element-binding factor 1 (SREBF1) gene with type 2 diabetes, glycemia, and insulin resistance: A study of 15,734 Danish subjects

    Grarup, N., Stender-Petersen, K. L., Andersson, E. A., Jorgensen, T., Borch-Johnsen, K., Sandbaek, A., Lauritzen, T., Schmitz, O., Hansen, Torben & Pedersen, Oluf Borbye, 2008, In: Diabetes.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Association of variants in the sterol regulatory element-binding factor 1 (SREBF1) gene with type 2 diabetes, glycemia, and insulin resistance: a study of 15,734 Danish subjects

    Grarup, N., Stender-Petersen, K. L., Andersson, E. A., Jørgensen, T., Borch-Johnsen, K., Sandbæk, A., Lauritzen, T., Schmitz, O., Hansen, T. & Pedersen, Oluf Borbye, 2008, In: Diabetes. 57, 4, p. 1136-42 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Association testing of novel type 2 diabetes risk alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 loci with insulin release, insulin sensitivity, and obesity in a population-based sample of 4,516 glucose-tolerant middle-aged Danes.

    Grarup, N., Andersen, G., Krarup, N. T., Albrechtsen, Anders, Schmitz, O., Jørgensen, T., Borch-Johnsen, K., Hansen, Torben & Pedersen, Oluf Borbye, 2008, In: Diabetes. 57, 9, p. 2534-40 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Autosomal inheritance of diabetes in two families characterized by obesity and a novel H241Q mutation in NEUROD1

    Gonsorcíková, L., Pruhová, S., Cinek, O., Ek, J., Pelikánová, T., Jørgensen, T., Eiberg, Hans Rudolf Lytchoff, Pedersen, Oluf Borbye, Hansen, T. & Lebl, J., 2008, In: Pediatric Diabetes. 9, 4 Pt 2, p. 367-72 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Common nonsynonymous variants in PCSK1 confer risk of obesity.

    Benzinou, M., Creemers, J. W. M., Choquet, H., Lobbens, S., Dina, C., Durand, E., Guerardel, A., Boutin, P., Jouret, B., Heude, B., Balkau, B., Tichet, J., Marre, M., Potoczna, N., Horber, F., Le Stunff, C., Czernichow, S., Sandbæk, A., Lauritzen, T., Borch-Johnsen, K. & 12 others, Andersen, G., Kiess, W., Körner, A., Kovacs, P., Jacobson, P., Carlsson, L. M. S., Walley, A. J., Jørgensen, T., Hansen, Torben, Pedersen, Oluf Borbye, Meyre, D. & Froguel, P., 2008, In: Nature Genetics. 40, 8, p. 943-5 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Cost-effectiveness of intensified versus conventional multifactorial intervention in type 2 diabetes: results and projections from the Steno-2 study

    Gaede, P., Valentine, W. J., Palmer, A. J., Tucker, D. M. D., Lammert, M., Parving, H. & Pedersen, Oluf Borbye, 2008, In: Diabetes Care. 31, 8, p. 1510-5 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Effect of a multifactorial intervention on mortality in type 2 diabetes

    Gaede, P., Lund-Andersen, H., Parving, H. & Pedersen, Oluf Borbye, 2008, In: New England Journal of Medicine. 358, 6, p. 580-91 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Effects of treatment with glucagon-like peptide-2 on bone resorption in colectomized patients with distal ileostomy or jejunostomy and short-bowel syndrome

    Gottschalck, I. B., Jeppesen, Palle Bekker, Hartmann, Bolette, Holst, Jens Juul & Henriksen, D. B., 2008, In: Scandinavian Journal of Gastroenterology. 43, 11, p. 1304-10 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Endocannabinoid receptor 1 gene variations increase risk for obesity and modulate body mass index in European populations

    Benzinou, M., Chèvre, J., Ward, K. J., Lecoeur, C., Dina, C., Lobbens, S., Durand, E., Delplanque, J., Horber, F. F., Heude, B., Balkau, B., Borch-Johnsen, K., Jørgensen, T., Hansen, T., Pedersen, Oluf Borbye, Meyre, D. & Froguel, P., 2008, In: Human Molecular Genetics. 17, 13, p. 1916-21 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    FTO gene associated fatness in relation to body fat distribution and metabolic traits throughout a broad range of fatness

    Kring, S. I. I., Holst, C., Zimmermann, E., Jess, T., Berentzen, T., Toubro, S., Hansen, Torben, Astrup, A., Pedersen, Oluf Borbye & Sørensen, Thorkild I.A., 2008, In: PLoS ONE. 3, 8, p. e2958 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Genetic analysis of Kruppel-like zinc finger 11 variants in 5864 Danish individuals: potential effect on insulin resistance and modified signal transducer and activator of transcription-3 binding by promoter variant -1659G>C

    Gutiérrez-Aguilar, R., Froguel, P., Hamid, Y. H., Benmezroua, Y., Jørgensen, T., Borch-Johnsen, K., Hansen, T., Pedersen, Oluf Borbye & Neve, B., 2008, In: Journal of Clinical Endocrinology and Metabolism. 93, 8, p. 3128-35 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Genetikken ved ikkeautoimmun diabetes. Dansk Endokrinologisk Selskab

    Hansen, T., Pedersen, Oluf Borbye & Dansk Endokrinologisk Selskab, D. E. S., 2008, In: Ugeskrift for læger. 170, 12, p. 1021

    Research output: Contribution to journalReviewResearch

  14. Published

    Genotype-phenotype associations in obesity dependent on definition of the obesity phenotype

    Kring, S. I. I., Larsen, L. H., Holst, C., Toubro, S., Hansen, Torben, Astrup, A., Pedersen, Oluf Borbye & Sørensen, Thorkild I.A., 2008, In: Obesity Facts. 1, 3, p. 138-145 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Impact of TCF7L2 rs7903146 on insulin secretion and action in young and elderly Danish twins.

    Wegner, L., Hussain, M. S., Pilgaard, K., Hansen, T., Pedersen, Oluf Borbye, Vaag, Allan & Poulsen, I. P., 2008, In: Journal of Clinical Endocrinology and Metabolism. 93, 10, p. 4013-9 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Impact of metformin versus repaglinide on non-glycaemic cardiovascular risk markers related to inflammation and endothelial dysfunction in non-obese patients with type 2 diabetes

    Lund, S. S., Tarnow, L., Stehouwer, C. D. A., Schalkwijk, C. G., Teerlink, T., Gram, J., Winther, K., Frandsen, M., Smidt, U. M., Pedersen, Oluf Borbye, Parving, H. & Vaag, Allan, 2008, In: European Journal of Endocrinology. 158, 5, p. 631-41 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Impact of metformin versus the prandial insulin secretagogue, repaglinide, on fasting and postprandial glucose and lipid responses in non-obese patients with type 2 diabetes

    Lund, S. S., Tarnow, L., Frandsen, M., Smidt, U. M., Pedersen, Oluf Borbye, Parving, H. & Vaag, Allan, 2008, In: European Journal of Endocrinology. 158, 1, p. 35-46 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Impact of polymorphisms in WFS1 on prediabetic phenotypes in a population-based sample of middle-aged people with normal and abnormal glucose regulation

    Sparsø, T., Andersen, G., Albrechtsen, Anders, Jørgensen, T., Borch-Johnsen, K., Sandbaek, A., Lauritzen, T., Wasson, J., Permutt, M. A., Glaser, B., Madsbad, Sten, Pedersen, Oluf Borbye & Hansen, Torben, 2008, In: Diabetologia. 51, 9, p. 1646-52 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Impact on weight dynamics and general growth of the common FTO rs9939609: a longitudinal Danish cohort study

    Jess, T., Zimmermann, E., Kring, S. I. I., Berentzen, T., Holst, C., Toubro, S., Astrup, A., Hansen, Torben, Pedersen, O., Sørensen, Thorkild I.A. & Pedersen, Oluf Borbye, 2008, In: International Journal of Obesity. 32, 9, p. 1388-94 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Impaired fasting glycaemia vs impaired glucose tolerance: similar impairment of pancreatic alpha and beta cell function but differential roles of incretin hormones and insulin action

    Faerch, K., Vaag, Allan, Holst, Jens Juul, Glümer, C., Pedersen, Oluf Borbye & Borch-Johnsen, K., 2008, In: Diabetologia. 51, 5, p. 853-61 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Implicit knowledge of visual uncertainty guides decisions with asymmetric outcomes

    Whiteley, Louise & Sahani, M., 2008, In: Journal of Vision. 8, 3, p. 2.1-15

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Increased recovery rates of phosphocreatine (PCr) and inorganic phosphate (Pi) after isometric contraction in oxidative muscle fibres and elevated hepatic insulin resistance in carriers of the fat mass and obesity-associated FTO genotypes

    Grunnet, Louise Groth, Brøns, C., Jacobsen, S., Nielsen, E., Astrup, A., Hansen, T., Pedersen, Oluf Borbye, Poulsen, P., Quistorff, B. & Vaag, A., 2008, In: Diabetes. 57, Suppl. 1, p. A329 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

  23. Published

    Insulin sensitivity, insulin release and glucagon-like peptide-1 levels in persons with impaired fasting glucose and/or impaired glucose tolerance in the EUGENE2 study

    Laakso, M., Zilinskaite, J., Hansen, Torben, Boesgaard, T. W., Vänttinen, M., Stancáková, A., Jansson, P., Pellmé, F., Kuulasmaa, T., Hribal, M. L., Sesti, G., Stefan, N., Fritsche, A., Häring, H., Pedersen, Oluf Borbye, Smith, U., EUGENE2 Consortium, E. C. & Holst, Jens Juul, 2008, In: Diabetologia. 51, 3, p. 502-11 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Lack of association between PKLR rs3020781 and NOS1AP rs7538490 and type 2 diabetes, overweight, obesity and related metabolic phenotypes in a Danish large-scale study: case-control studies and analyses of quantitative traits

    Andreasen, C. H., Mogensen, M. S., Borch-Johnsen, K., Sandbæk, A., Lauritzen, T., Almind, K., Pedersen, Oluf Borbye, Hansen, L., Jørgensen, T. & Hansen, Torben, 2008, In: BMC Medical Genetics. 9, p. 118

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Lack of association of fatness-related FTO gene variants with energy expenditure or physical activity

    Berentzen, T., Kring, S. I. I., Holst, C., Zimmermann, E., Jess, T., Hansen, T., Pedersen, Oluf Borbye, Toubro, S., Astrup, A. & Sørensen, Thorkild I.A., 2008, In: Journal of Clinical Endocrinology and Metabolism. 93, 7, p. 2904-2908 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Low physical activity accentuates the effect of the FTO rs9939609 polymorphism on body fat accumulation

    Andreasen, C. H., Stender-Petersen, K. L., Mogensen, M. S., Torekov, Signe Sørensen, Wegner, L., Andersen, G., Nielsen, A. L., Albrechtsen, Anders, Borch-Johnsen, K., Rasmussen, S. S., Clausen, J. O., Sandbaek, A., Lauritzen, T., Hansen, L., Jørgensen, T., Pedersen, Oluf Borbye & Hansen, T., 2008, In: Diabetes. 57, 1, p. 95-101 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review