Novo Nordisk Foundation Center for Basic Metabolic Research

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  1. 2008
  2. Published

    Single-nucleotide polymorphism rs7754840 of CDKAL1 is associated with impaired insulin secretion in nondiabetic offspring of type 2 diabetic subjects and in a large sample of men with normal glucose tolerance

    Stancáková, A., Pihlajamäki, J., Kuusisto, J., Stefan, N., Fritsche, A., Häring, H., Andreozzi, F., Succurro, E., Sesti, G., Boesgaard, T. W., Hansen, T., Pedersen, Oluf Borbye, Jansson, P. A., Hammarstedt, A., Smith, U., Laakso, M. & EUGENE2 Consortium, E. C., 2008, In: Journal of Clinical Endocrinology and Metabolism. 93, 5, p. 1924-30 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    The -250G>A promoter variant in hepatic lipase associates with elevated fasting serum high-density lipoprotein cholesterol modulated by interaction with physical activity in a study of 16,156 Danish subjects

    Grarup, N., Andreasen, C. H., Lepola, Mette Andersen, Albrechtsen, Anders, Sandbaek, A., Lauritzen, T., Borch-Johnsen, K., Jørgensen, T., Schmitz, O., Hansen, T. & Pedersen, Oluf Borbye, 2008, In: Journal of Clinical Endocrinology and Metabolism. 93, 6, p. 2294-9 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    The Gly482Ser genotype at the PPARGC1A gene and elevated blood pressure: a meta-analysis involving 13,949 individuals

    Vimaleswaran, K. S., Luan, J., Andersen, G., Muller, Y. L., Wheeler, E., Brito, E. C., O'Rahilly, S., Pedersen, Oluf Borbye, Baier, L. J., Knowler, W. C., Barroso, I., Wareham, N. J., Loos, R. J. F. & Franks, P. W., 2008, In: Journal of Applied Physiology. 105, 4, p. 1352-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    The KCNMB1 Glu65Lys polymorphism associates with reduced systolic and diastolic blood pressure in the Inter99 study of 5729 Danes.

    Nielsen, T., Burgdorf, K. S., Grarup, N., Borch-Johnsen, K., Hansen, T., Jørgensen, T., Pedersen, Oluf Borbye & Andersen, G., 2008, In: Journal of Hypertension. 26, 11, p. 2142-6 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    The PPAR gamma 2 Pro12Ala variant predicts ESRD and mortality in patients with type 1 diabetes and diabetic nephropathy

    Jorsal, A., Tarnow, L., Lajer, M., Ek, J., Hansen, Torben, Pedersen, Oluf Borbye & Parving, H., 2008, In: Molecular Genetics and Metabolism. 94, 3, p. 347-51 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    The common SLC30A8 Arg325Trp variant is associated with reduced first-phase insulin release in 846 non-diabetic offspring of type 2 diabetes patients--the EUGENE2 study

    Boesgaard, T. W., Zilinskaite, J., Vänttinen, M., Laakso, M., Jansson, P., Hammarstedt, A., Smith, U., Stefan, N., Fritsche, A., Häring, H., Hribal, M., Sesti, G., Zobel, D. P., Pedersen, Oluf Borbye, Hansen, Torben & EUGENE 2 Consortium, E. 2. C., 2008, In: Diabetologia. 51, 5, p. 816-20 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm

    Helgadottir, A., Thorleifsson, G., Magnusson, K. P., Grétarsdottir, S., Steinthorsdottir, V., Manolescu, A., Jones, G. T., Rinkel, G. J. E., Blankensteijn, J. D., Ronkainen, A., Jääskeläinen, J. E., Kyo, Y., Lenk, G. M., Sakalihasan, N., Kostulas, K., Gottsäter, A., Flex, A., Stefansson, H., Hansen, T., Andersen, G. & 48 others, Weinsheimer, S., Borch-Johnsen, K., Jørgensen, T., Shah, S. H., Quyyumi, A. A., Granger, C. B., Reilly, M. P., Austin, H., Levey, A. I., Vaccarino, V., Palsdottir, E., Walters, G. B., Jonsdottir, T., Snorradottir, S., Magnusdottir, D., Gudmundsson, G., Ferrell, R. E., Sveinbjornsdottir, S., Hernesniemi, J., Niemelä, M., Limet, R., Andersen, K., Sigurdsson, G., Benediktsson, R., Verhoeven, E. L. G., Teijink, J. A. W., Grobbee, D. E., Rader, D. J., Collier, D. A., Pedersen, Oluf Borbye, Pola, R., Hillert, J., Lindblad, B., Valdimarsson, E. M., Magnadottir, H. B., Wijmenga, C., Tromp, G., Baas, A. F., Ruigrok, Y. M., van Rij, A. M., Kuivaniemi, H., Powell, J. T., Matthiasson, S. E., Gulcher, J. R., Thorgeirsson, G., Kong, A., Thorsteinsdottir, U. & Stefansson, K., 2008, In: Nature Genetics. 40, 2, p. 217-24 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Uncertainty, reward, and attention in the Bayesian brain

    Whiteley, Louise, 2008

    Research output: Book/Report › Ph.D. thesis

  10. Published

    Variance of the SGK1 gene is associated with insulin secretion in different European populations: results from the TUEF, EUGENE2, and METSIM studies.

    Friedrich, B., Weyrich, P., Stancáková, A., Wang, J., Kuusisto, J., Laakso, M., Sesti, G., Succurro, E., Smith, U., Hansen, Torben, Pedersen, Oluf Borbye, Machicao, F., Schäfer, S., Lang, F., Risler, T., Ullrich, S., Stefan, N., Fritsche, A. & Häring, H., 2008, In: PLoS ONE. 3, 11, p. e3506

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels

    Chen, W-M., Erdos, M. R., Jackson, A. U., Saxena, R., Sanna, S., Silver, K. D., Timpson, N. J., Hansen, T., Orrù, M., Grazia Piras, M., Bonnycastle, L. L., Willer, C. J., Lyssenko, V., Shen, H., Kuusisto, J., Ebrahim, S., Sestu, N., Duren, W. L., Spada, M. C., Stringham, H. M. & 31 others, Scott, L. J., Olla, N., Swift, A. J., Najjar, S., Mitchell, B. D., Lawlor, D. A., Smith, G. D., Ben-Shlomo, Y., Andersen, G., Borch-Johnsen, K., Jørgensen, T., Saramies, J., Valle, T. T., Buchanan, T. A., Shuldiner, A. R., Lakatta, E., Bergman, R. N., Uda, M., Tuomilehto, J., Pedersen, Oluf Borbye, Cao, A., Groop, L., Mohlke, K. L., Laakso, M., Schlessinger, D., Collins, F. S., Altshuler, D., Abecasis, G. R., Boehnke, M., Scuteri, A. & Watanabe, R. M., 2008, In: Journal of Clinical Investigation. 118, 7, p. 2620-8 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Visual processing and the bodily self

    Whiteley, Louise, Spence, C. & Haggard, P., 2008, In: Acta Psychologica. 127, 1, p. 129-36 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. 2007
  14. Published

    Discovery and uses of pegvisomant: A growth hormone antagonist

    Berryman, D. E., Palmer, A. J., Gosney, E. S., Swaminathan, S., DeSantis, D. & Kopchick, J. J., 1 Dec 2007, In: Endokrynologia Polska. 58, 4, p. 322-329 8 p.

    Research output: Contribution to journal › Review › Research › peer-review

  15. Published

    Concentrations of the acute phase reactants high-sensitive C-reactive protein and YKL-40 and of interleukin-6 before and after treatment in patients with acromegaly and growth hormone deficiency

    Andreassen, Mikkel, drb459, drb459 & Kristensen, L. Ø., Dec 2007, In: Clinical Endocrinology. 67, 6, p. 909-16 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Bone resorption is decreased postprandially by intestinal factors and glucagon-like peptide-2 is a possible candidate

    Holst, Jens Juul, Hartmann, Bolette, Gottschalck, I. B., Jeppesen, Palle Bekker, Miholic, J. & Henriksen, D. B., Jul 2007, In: Scandinavian Journal of Gastroenterology. 42, 7, p. 814-20 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1α

    Gerhart-Hines, Zach, Rodgers, J. T., Bare, O., Lerin, C., Kim, S. H., Mostoslavsky, R., Alt, F. W., Wu, Z. & Puigserver, P., 4 Apr 2007, In: EMBO Journal. 26, 7, p. 1913-1923 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    The human PINK1 locus is regulated in vivo by a non-coding natural antisense RNA during modulation of mitochondrial function

    Schéele, Camilla Charlotte Nielsen, Petrovic, N., Faghihi, M. A., Lassmann, T., Fredriksson, K., Rooyackers, O., Wahlestedt, C., Good, L. & Timmons, J. A., 15 Mar 2007, In: BMC Genomics. 8, p. 74

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Disassociation of bone resorption and formation by GLP-2: a 14-day study in healthy postmenopausal women

    Henriksen, D. B., Alexandersen, P., Hartmann, Bolette, Adrian, C. L., Byrjalsen, I., Bone, H. G., Holst, Jens Juul & Christiansen, C., Mar 2007, In: Bone. 40, 3, p. 723-9 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Studies of the associations between functional beta2-adrenergic receptor variants and obesity, hypertension and type 2 diabetes in 7,808 white subjects

    Gjesing, A. P., Andersen, G., Burgdorf, Kristoffer Sølvsten, Borch-Johnsen, K., Jørgensen, T., Hansen, Torben & Pedersen, Oluf Borbye, Mar 2007, In: Diabetologia. 50, 3, p. 563-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    The Treeterbi and Parallel Treeterbi algorithms: efficient, optimal decoding for ordinary, generalized and pair HMMs.

    Keibler, E., Arumugam, Mani & Brent, M. R., Mar 2007, In: Bioinformatics. 23, 5, p. 545-554 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    A common haplotype in the G-protein-coupled receptor gene GPR74 is associated with leanness and increased lipolysis

    Dahlman, I., Dicker, A., Jiao, H., Kere, J., Blomqvist, L., van Harmelen, V., Hoffstedt, J., Borch-Johnsen, K., Jorgensen, T., Hansen, Torben, Pedersen, Oluf Borbye, Laakso, M. & Arner, P., 2007, In: American Journal of Human Genetics. 80, 6, p. 1115-24 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    A variant in CDKAL1 influences insulin response and risk of type 2 diabetes

    Steinthorsdottir, V., Thorleifsson, G., Reynisdottir, I., Benediktsson, R., Jonsdottir, T., Walters, G. B., Styrkarsdottir, U., Gretarsdottir, S., Emilsson, V., Ghosh, S., Baker, A., Snorradottir, S., Bjarnason, H., Ng, M. C. Y., Hansen, T., Bagger, Y., Wilensky, R. L., Reilly, M. P., Adeyemo, A., Chen, Y. & 25 others, Zhou, J., Gudnason, V., Chen, G., Huang, H., Lashley, K., Doumatey, A., So, W., Ma, R. C. Y., Andersen, G., Borch-Johnsen, K., Jorgensen, T., van Vliet-Ostaptchouk, J. V., Hofker, M. H., Wijmenga, C., Christiansen, C., Rader, D. J., Rotimi, C., Gurney, M., Chan, J. C. N., Pedersen, Oluf Borbye, Sigurdsson, G., Gulcher, J. R., Thorsteinsdottir, U., Kong, A. & Stefansson, K., 2007, In: Nature Genetics. 39, 6, p. 770-5 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    AS160 phosphorylation is associated with activation of alpha(2)beta(2)gamma(1)- but not alpha(2)beta(2)gamma(3)-AMPK trimeric complex in skeletal muscle during exercise in humans

    Treebak, Jonas Thue, Birk, Jesper Bratz, Rose, A. J., Kiens, Bente, Richter, Erik A. & Wojtaszewski, Jørgen F P, 2007, In: American Journal of Physiology-Endocrinology and Metabolism.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Association between obesity and asthma in a twin cohort

    Thomsen, S., Ulrik, Charlotte Suppli, Kyvik, K., Sørensen, Thorkild I.A., Posthuma, D., Skadhauge, L., Steffensen, I. & Backer, V., 2007, In: Allergy. European Journal of Allergy and Clinical Immunology. 62, 10, p. 1199-1204 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Common variation in LMNA increases susceptibility to type 2 diabetes and associates with elevated fasting glycemia and estimates of body fat and height in the general population: studies of 7,495 Danish whites

    Wegner, L., Andersen, G., Sparsø, T., Grarup, N., Glümer, C., Borch-Johnsen, K., Jørgensen, T., Hansen, Torben & Pedersen, Oluf Borbye, 2007, In: Diabetes. 56, 3, p. 694-8 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Genetic analysis of the estrogen-related receptor alpha and studies of association with obesity and type 2 diabetes

    Larsen, L. H., Rose, C. S., Sparsø, T., Overgaard, J., Torekov, Signe Sørensen, Grarup, N., Jensen, Dan Funck, Albrechtsen, Anders, Andersen, G., Ek, J., Glümer, C., Borch-Johnsen, K., Jørgensen, Tina, Hansen, Teis Schjals & Pedersen, Oluf Borbye, 2007, In: International Journal of Obesity. 31, 2, p. 365-70 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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