Novo Nordisk Foundation Center for Basic Metabolic Research

  1. 2008
  2. Published

    Low physical activity accentuates the effect of the FTO rs9939609 polymorphism on body fat accumulation

    Andreasen, C. H., Stender-Petersen, K. L., Mogensen, M. S., Torekov, Signe Sørensen, Wegner, L., Andersen, G., Nielsen, A. L., Albrechtsen, Anders, Borch-Johnsen, K., Rasmussen, S. S., Clausen, J. O., Sandbaek, A., Lauritzen, T., Hansen, L., Jørgensen, T., Pedersen, Oluf Borbye & Hansen, T., 2008, In: Diabetes. 57, 1, p. 95-101 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Many sequence variants affecting diversity of adult human height

    Gudbjartsson, D. F., Walters, G. B., Thorleifsson, G., Stefansson, H., Halldorsson, B. V., Zusmanovich, P., Sulem, P., Thorlacius, S., Gylfason, A., Steinberg, S., Helgadottir, A., Ingason, A., Steinthorsdottir, V., Olafsdottir, E. J., Olafsdottir, G. H., Jonsson, T., Borch-Johnsen, K., Hansen, T., Andersen, G., Jørgensen, T. & 17 others, Pedersen, Oluf Borbye, Aben, K. K., Witjes, J. A., Swinkels, D. W., den Heijer, M., Franke, B., Verbeek, A. L. M., Becker, D. M., Yanek, L. R., Becker, L. C., Tryggvadottir, L., Rafnar, T., Gulcher, J., Kiemeney, L. A., Kong, A., Thorsteinsdottir, U. & Stefansson, K., 2008, In: Nature Genetics. 40, 5, p. 609-15 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

    Zeggini, E., Scott, L. J., Saxena, R., Voight, B. F., Marchini, J. L., Hu, T., de Bakker, P. I. W., Abecasis, G. R., Almgren, P., Andersen, G., Ardlie, K., Boström, K. B., Bergman, R. N., Bonnycastle, L. L., Borch-Johnsen, K., Burtt, N. P., Chen, H., Chines, P. S., Daly, M. J., Deodhar, P. & 31 others, Ding, C., Doney, A. S. F., Duren, W. L., Elliott, K. S., Erdos, M. R., Frayling, T. M., Freathy, R. M., Gianniny, L., Grallert, H., Grarup, N., Groves, C. J., Guiducci, C., Hansen, Torben, Herder, C., Hitman, G. A., Hughes, T. E., Isomaa, B., Jackson, A. U., Jørgensen, T., Kong, A., Kubalanza, K., Kuruvilla, F. G., Kuusisto, J., Langenberg, C., Lango, H., Lauritzen, T., Li, Y., Lindgren, C. M., Lyssenko, V., Wellcome Trust Case Control Consortium, W. T. C. C. C. & Pedersen, Oluf Borbye, 2008, In: Nature Genetics. 40, 5, p. 638-45 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Multifactorial intervention and mortallity in type 2 diabetes- Reply

    Gaede, P., Parving, H. & Pedersen, Oluf Borbye, 2008, In: New England Journal of Medicine. p. 358: 2292-2293

    Research output: Contribution to journalComment/debateResearch

  6. Published

    Non-replication of genome-wide based associations between common variants in INSIG2 and PFKP and obesity in studies of 18,014 Danes

    Sandholt, C. H., Mogensen, M. S., Borch-Johnsen, K., Sandbaek, A., Lauritzen, T., Sørensen, Thorkild I.A., Hansen, L., Almind, K., Jørgensen, T., Pedersen, Oluf Borbye & Hansen, Torben, 2008, In: PLoS ONE. 3, 8, p. e2872 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Polymorphisms in AHI1 are not associated with type 2 diabetes or related phenotypes in Danes: non-replication of a genome-wide association result

    Holmkvist, J., Anthonsen, S., Wegner, L., Andersen, G., Jørgensen, T., Borch-Johnsen, K., Sandbaek, A., Lauritzen, T., Pedersen, Oluf Borbye & Hansen, Torben, 2008, In: Diabetologia. 51, 4, p. 609-14 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Possible role of AS160 in post-exercise increased insulin sensitivity in human skeletal muscle

    Treebak, Jonas Thue, Kristensen, Jonas Møller, Frosig, C., Pehmoller, C., Hardie, D. G., Kiens, Bente, Richter, Erik A. & Wojtaszewski, Jørgen F P, 2008, In: Diabetes.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Receptorji s sedmimi transmembranskimi območji (7TM) v luči dimerizacije ter eksperimentalni pristopi za proučevanje njihove dimerizacije in medsebojnih vplivov

    Kubale, V., Pogačnik, A., Schwartz, Thue W. & Vrecl, M., 2008, In: Slovenian Veterinary Research. 45, 3, p. 89-102 14 p.

    Research output: Contribution to journalReviewResearchpeer-review

  10. Published

    Role of AMPK in IL-6 release from isolated mouse skeletal muscle

    Glund, S., Treebak, Jonas Thue, Long, Y. C., Barrès, Romain, Viollet, B., Wojtaszewski, Jørgen F P & Zierath, Juleen R, 2008, In: Diabetologia.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations.

    Unoki, H., Takahashi, A., Kawaguchi, T., Hara, K., Horikoshi, M., Andersen, G., Ng, D. P. K., Holmkvist, J., Borch-Johnsen, K., Jørgensen, T., Sandbæk, A., Lauritzen, T., Hansen, T., Nurbaya, S., Tsunoda, T., Kubo, M., Babazono, T., Hirose, H., Hayashi, M., Iwamoto, Y. & 10 others, Kashiwagi, A., Kaku, K., Kawamori, R., Tai, E. S., Pedersen, Oluf Borbye, Kamatani, N., Kadowaki, T., Kikkawa, R., Nakamura, Y. & Maeda, S., 2008, In: Nature Genetics. 40, 9, p. 1098-1102 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Seven mutations in the human insulin gene linked to permanent neonatal/infancy-onset diabetes mellitus

    Colombo, C., Porzio, O., Liu, M., Massa, O., Vasta, M., Salardi, S., Beccaria, L., Monciotti, C., Toni, S., Pedersen, Oluf Borbye, Hansen, T., Federici, L., Pesavento, R., Cadario, F., Federici, G., Ghirri, P., Arvan, P., Iafusco, D., Barbetti, F. & Early Onset Diabetes Study Group of the Italian Society of Pediatric Endocrinology and Diabetes (SIEDP), E. O. D. S. G. O. T. I. S. O. P. E. A. D. (., 2008, In: Journal of Clinical Investigation. 118, 6, p. 2148-56 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Single-nucleotide polymorphism rs7754840 of CDKAL1 is associated with impaired insulin secretion in nondiabetic offspring of type 2 diabetic subjects and in a large sample of men with normal glucose tolerance

    Stancáková, A., Pihlajamäki, J., Kuusisto, J., Stefan, N., Fritsche, A., Häring, H., Andreozzi, F., Succurro, E., Sesti, G., Boesgaard, T. W., Hansen, T., Pedersen, Oluf Borbye, Jansson, P. A., Hammarstedt, A., Smith, U., Laakso, M. & EUGENE2 Consortium, E. C., 2008, In: Journal of Clinical Endocrinology and Metabolism. 93, 5, p. 1924-30 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    The -250G>A promoter variant in hepatic lipase associates with elevated fasting serum high-density lipoprotein cholesterol modulated by interaction with physical activity in a study of 16,156 Danish subjects

    Grarup, N., Andreasen, C. H., Lepola, Mette Andersen, Albrechtsen, Anders, Sandbaek, A., Lauritzen, T., Borch-Johnsen, K., Jørgensen, T., Schmitz, O., Hansen, T. & Pedersen, Oluf Borbye, 2008, In: Journal of Clinical Endocrinology and Metabolism. 93, 6, p. 2294-9 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    The Gly482Ser genotype at the PPARGC1A gene and elevated blood pressure: a meta-analysis involving 13,949 individuals

    Vimaleswaran, K. S., Luan, J., Andersen, G., Muller, Y. L., Wheeler, E., Brito, E. C., O'Rahilly, S., Pedersen, Oluf Borbye, Baier, L. J., Knowler, W. C., Barroso, I., Wareham, N. J., Loos, R. J. F. & Franks, P. W., 2008, In: Journal of Applied Physiology. 105, 4, p. 1352-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    The KCNMB1 Glu65Lys polymorphism associates with reduced systolic and diastolic blood pressure in the Inter99 study of 5729 Danes.

    Nielsen, T., Burgdorf, K. S., Grarup, N., Borch-Johnsen, K., Hansen, T., Jørgensen, T., Pedersen, Oluf Borbye & Andersen, G., 2008, In: Journal of Hypertension. 26, 11, p. 2142-6 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    The PPAR gamma 2 Pro12Ala variant predicts ESRD and mortality in patients with type 1 diabetes and diabetic nephropathy

    Jorsal, A., Tarnow, L., Lajer, M., Ek, J., Hansen, Torben, Pedersen, Oluf Borbye & Parving, H., 2008, In: Molecular Genetics and Metabolism. 94, 3, p. 347-51 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    The common SLC30A8 Arg325Trp variant is associated with reduced first-phase insulin release in 846 non-diabetic offspring of type 2 diabetes patients--the EUGENE2 study

    Boesgaard, T. W., Zilinskaite, J., Vänttinen, M., Laakso, M., Jansson, P., Hammarstedt, A., Smith, U., Stefan, N., Fritsche, A., Häring, H., Hribal, M., Sesti, G., Zobel, D. P., Pedersen, Oluf Borbye, Hansen, Torben & EUGENE 2 Consortium, E. 2. C., 2008, In: Diabetologia. 51, 5, p. 816-20 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm

    Helgadottir, A., Thorleifsson, G., Magnusson, K. P., Grétarsdottir, S., Steinthorsdottir, V., Manolescu, A., Jones, G. T., Rinkel, G. J. E., Blankensteijn, J. D., Ronkainen, A., Jääskeläinen, J. E., Kyo, Y., Lenk, G. M., Sakalihasan, N., Kostulas, K., Gottsäter, A., Flex, A., Stefansson, H., Hansen, T., Andersen, G. & 48 others, Weinsheimer, S., Borch-Johnsen, K., Jørgensen, T., Shah, S. H., Quyyumi, A. A., Granger, C. B., Reilly, M. P., Austin, H., Levey, A. I., Vaccarino, V., Palsdottir, E., Walters, G. B., Jonsdottir, T., Snorradottir, S., Magnusdottir, D., Gudmundsson, G., Ferrell, R. E., Sveinbjornsdottir, S., Hernesniemi, J., Niemelä, M., Limet, R., Andersen, K., Sigurdsson, G., Benediktsson, R., Verhoeven, E. L. G., Teijink, J. A. W., Grobbee, D. E., Rader, D. J., Collier, D. A., Pedersen, Oluf Borbye, Pola, R., Hillert, J., Lindblad, B., Valdimarsson, E. M., Magnadottir, H. B., Wijmenga, C., Tromp, G., Baas, A. F., Ruigrok, Y. M., van Rij, A. M., Kuivaniemi, H., Powell, J. T., Matthiasson, S. E., Gulcher, J. R., Thorgeirsson, G., Kong, A., Thorsteinsdottir, U. & Stefansson, K., 2008, In: Nature Genetics. 40, 2, p. 217-24 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Uncertainty, reward, and attention in the Bayesian brain

    Whiteley, Louise, 2008

    Research output: Book/ReportPh.D. thesis

  21. Published

    Variance of the SGK1 gene is associated with insulin secretion in different European populations: results from the TUEF, EUGENE2, and METSIM studies.

    Friedrich, B., Weyrich, P., Stancáková, A., Wang, J., Kuusisto, J., Laakso, M., Sesti, G., Succurro, E., Smith, U., Hansen, Torben, Pedersen, Oluf Borbye, Machicao, F., Schäfer, S., Lang, F., Risler, T., Ullrich, S., Stefan, N., Fritsche, A. & Häring, H., 2008, In: PLoS ONE. 3, 11, p. e3506

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels

    Chen, W-M., Erdos, M. R., Jackson, A. U., Saxena, R., Sanna, S., Silver, K. D., Timpson, N. J., Hansen, T., Orrù, M., Grazia Piras, M., Bonnycastle, L. L., Willer, C. J., Lyssenko, V., Shen, H., Kuusisto, J., Ebrahim, S., Sestu, N., Duren, W. L., Spada, M. C., Stringham, H. M. & 31 others, Scott, L. J., Olla, N., Swift, A. J., Najjar, S., Mitchell, B. D., Lawlor, D. A., Smith, G. D., Ben-Shlomo, Y., Andersen, G., Borch-Johnsen, K., Jørgensen, T., Saramies, J., Valle, T. T., Buchanan, T. A., Shuldiner, A. R., Lakatta, E., Bergman, R. N., Uda, M., Tuomilehto, J., Pedersen, Oluf Borbye, Cao, A., Groop, L., Mohlke, K. L., Laakso, M., Schlessinger, D., Collins, F. S., Altshuler, D., Abecasis, G. R., Boehnke, M., Scuteri, A. & Watanabe, R. M., 2008, In: Journal of Clinical Investigation. 118, 7, p. 2620-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Visual processing and the bodily self

    Whiteley, Louise, Spence, C. & Haggard, P., 2008, In: Acta Psychologica. 127, 1, p. 129-36 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. 2007
  25. Published

    Discovery and uses of pegvisomant: A growth hormone antagonist

    Berryman, D. E., Palmer, A. J., Gosney, E. S., Swaminathan, S., DeSantis, D. & Kopchick, J. J., 1 Dec 2007, In: Endokrynologia Polska. 58, 4, p. 322-329 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  26. Published

    Concentrations of the acute phase reactants high-sensitive C-reactive protein and YKL-40 and of interleukin-6 before and after treatment in patients with acromegaly and growth hormone deficiency

    Andreassen, Mikkel, drb459, drb459 & Kristensen, L. Ø., Dec 2007, In: Clinical Endocrinology. 67, 6, p. 909-16 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Bone resorption is decreased postprandially by intestinal factors and glucagon-like peptide-2 is a possible candidate

    Holst, Jens Juul, Hartmann, Bolette, Gottschalck, I. B., Jeppesen, Palle Bekker, Miholic, J. & Henriksen, D. B., Jul 2007, In: Scandinavian Journal of Gastroenterology. 42, 7, p. 814-20 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review