Novo Nordisk Foundation Center for Basic Metabolic Research

  1. 2007
  2. Published

    Studies of the common DIO2 Thr92Ala polymorphism and metabolic phenotypes in 7342 Danish white subjects

    Grarup, N., Lepola, Mette Andersen, Andreasen, C. H., Albrechtsen, Anders, Borch-Johnsen, K., Jørgensen, T., Auwerx, J., Schmitz, O., Hansen, Torben & Pedersen, Oluf Borbye, 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 1, p. 363-6 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    The BIGTT test: a novel test for simultaneous measurement of pancreatic beta-cell function, insulin sensitivity, and glucose tolerance

    Hansen, Torben, Drivsholm, Thomas, Urhammer, S. A., Palacios, R. T., Vølund, A., Borch-Johnsen, K. & Pedersen, Oluf Borbye, 2007, In: Diabetes Care. 30, 2, p. 257-262 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes

    Sparsø, T., Andersen, G., Nielsen, T., Burgdorf, K. S., Gjesing, A. M. P., Nielsen, A. L., Albrechtsen, Anders, Rasmussen, S. S., Jørgensen, T., Borch-Johnsen, K., Sandbaek, A., Lauritzen, T., Madsbad, Sten, Hansen, Torben & Pedersen, Oluf Borbye, 2007, In: Diabetologia. 51, 1, p. 70-5 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    The functional Pro129Thr variant of the FAAH gene is not associated with various fat accumulation phenotypes in a population-based cohort of 5,801 whites

    Jensen, D. P., Lepola, Mette Andersen, Hansen, L., Eiberg, Hans Rudolf Lytchoff, Borch-Johnsen, K., Jørgensen, T., Hansen, Torben, Pedersen, Oluf Borbye & Andreasen, C. H., 2007, In: Journal of Molecular Medicine. 85, 5, p. 445-9 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    The “mesh” as evidence – model comparison and alternative interpretations of feedback

    Hulme, Oliver James & Whiteley, Louise, 2007, In: Behavioral and Brain Sciences. 30

    Research output: Contribution to journalComment/debateCommunication

  7. Published

    Thiazole- and pyrimidineacetic acid derivatives as CRTH2 receptor ligands, their preparation, pharmaceutical compositions, and use in therapy

    Ulven, Trond, Frimurer, Thomas Michael, Rist, Ø., Kostenis, E., Högberg, T., Receveur, J. & Grimstrup, M., 2007, Patent No. WO 2007/062677 A1

    Research output: Patent

  8. Published

    Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes

    Gudmundsson, J., Sulem, P., Steinthorsdottir, V., Bergthorsson, J. T., Thorleifsson, G., Manolescu, A., Rafnar, T., Gudbjartsson, D., Agnarsson, B. A., Baker, A., Sigurdsson, A., Benediktsdottir, K. R., Jakobsdottir, M., Blondal, T., Stacey, S. N., Helgason, A., Gunnarsdottir, S., Olafsdottir, A., Kristinsson, K. T., Birgisdottir, B. & 55 others, Ghosh, S., Thorlacius, S., Magnusdottir, D., Stefansdottir, G., Kristjansson, K., Bagger, Y., Wilensky, R. L., Reilly, M. P., Morris, A. D., Kimber, C. H., Adeyemo, A., Chen, Y., Zhou, J., So, W., Tong, P. C. Y., Ng, M. C. Y., Hansen, Torben, Andersen, G., Borch-Johnsen, K., Jorgensen, T., Tres, A., Fuertes, F., Ruiz-Echarri, M., Asin, L., Saez, B., van Boven, E., Klaver, S., Swinkels, D. W., Aben, K. K., Graif, T., Cashy, J., Suarez, B. K., van Vierssen Trip, O., Frigge, M. L., Ober, C., Hofker, M. H., Wijmenga, C., Christiansen, C., Rader, D. J., Palmer, C. N. A., Rotimi, C., Chan, J. C. N., Pedersen, Oluf Borbye, Sigurdsson, G., Benediktsson, R., Jonsson, E., Einarsson, G. V., Mayordomo, J. I., Catalona, W. J., Kiemeney, L. A., Barkardottir, R. B., Gulcher, J. R., Thorsteinsdottir, U., Kong, A. & Stefansson, K., 2007, In: Nature Genetics. 39, 8, p. 977-983 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 2006
  10. Published

    Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1α

    Lagouge, M., Argmann, C., Gerhart-Hines, Zach, Meziane, H., Lerin, C., Daussin, F., Messadeq, N., Milne, J., Lambert, P., Elliott, P., Geny, B., Laakso, M., Puigserver, P. & Auwerx, J., 15 Dec 2006, In: Cell. 127, 6, p. 1109-1122 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Enigma interacts with adaptor protein with PH and SH2 domains to control insulin-induced actin cytoskeleton remodeling and glucose transporter 4 translocation

    Barrès, Romain, Grémeaux, T., Gual, P., Gonzalez, T., Gugenheim, J., Tran, A., Le Marchand-Brustel, Y. & Tanti, J., Nov 2006, In: Molecular Endocrinology. 20, 11, p. 2864-75 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Mediastinalt parathyroideacysteadenom--en sjaelden årsag til primaer hyperparatyroidisme

    Øgard, C. G., Nielsen, S. L., Jakobsen, H., Leth-Espensen, P., drb459, drb459 & drb459, drb459, 28 Aug 2006, In: Ugeskrift for Laeger. 168, 35, p. 2921-2 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Cell specificity of the cytoplasmic Ca2+ response to tolbutamide is impaired in beta-cells from hyperglycemic mice

    Gustavsson, N., Larsson-Nyrén, G. & Lindström, P., Aug 2006, In: The Journal of endocrinology. 190, 2, p. 461-70 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    A liver specific gene that is expressed in growth hormone transgenic mice and in normal female mice as a function of age

    Tiong, J. D. R., Gosney, E., Ding, J., Chin, E. & Kopchick, J. J., 1 Jun 2006, In: Growth Hormone and IGF Research. 16, 3, p. 145-156 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    IRS-1 serine phosphorylation and insulin resistance in skeletal muscle from pancreas transplant recipients

    Bouzakri, K., Karlsson, H. K. R., drb459, drb459, Madsbad, Sten, Christiansen, E. & Zierath, Juleen R, Mar 2006, In: Diabetes. 55, 3, p. 785-91 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Timing of Ca2+ response in pancreatic beta-cells is related to mitochondrial mass

    Gustavsson, N., Abedi, G., Larsson-Nyrén, G. & Lindström, P., 24 Feb 2006, In: Molecular Cell Biology Research Communications. 340, 4, p. 1119-24 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Critical nodes in signalling pathways: insights into insulin action

    Taniguchi, C. M., Emanuelli, Brice & Kahn, C. R., Feb 2006, In: Nature Reviews. Molecular Cell Biology. 7, 2, p. 85-96 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Endocannabinoids

    Hansen, Harald S., Petersen, G., Artmann, A. & Madsen, A. N., 1 Jan 2006, In: European Journal of Lipid Science and Technology. 108, 10, p. 877-889 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    6-Acylamino-2-amino-4-methylquinolines as potent melanin-concentrating hormone 1 receptor antagonists

    Ulven, Trond, Little, P. B., Receveur, J., Frimurer, Thomas Michael, Rist, Ø., Nørregaard, P. K., Mathiesen, Jesper M. & Högberg, T., 2006, In: Bioorganic & Medicinal Chemistry Letters. 16, 4, p. 1070-1075 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    A novel -192c/g Mutation in the Proximal P2 Promoter of the Hepatocyte Nuclear Factor-4α Gene (HNF4A) Associates With Late-onset Diabetes

    Ek, J., Hansen, S. P., Lajer, M., Nicot, C., Boesgaard, T. W., Pruhova, S., Johansen, A., Albrechtsen, Anders, Yderstraede, K., Lauenborg, J., Parrizas, M., Boj, S. F., Jørgensen, T., Borch-Johnsen, K., Damm, Peter, Ferrer, J., Lebl, J., Pedersen, Oluf Borbye & Hansen, Torben, 2006, In: Diabetes. 55, 6, p. 1869-73 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    AMPK-mediated AS160 phosphorylation in skeletal muscle is dependent on AMPK catalytic and regulatory subunits.

    Treebak, Jonas Thue, Glund, S., Deshmukh, Atul Shahaji, Klein, D. K., Long, Y. C., Jensen, Thomas Elbenhardt, Jørgensen, S. B., Viollet, B., Andersson, L., Neumann, D., Wallimann, T., Richter, Erik A., Chibalin, A. V., Zierath, J. R. & Wojtaszewski, Jørgen F P, 2006, In: Diabetes. 55, 7, p. 2051-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Association between neuromedin U gene variants and overweight and obesity

    Hainerová, I., Torekov, Signe Sørensen, Ek, J., Finková, M., Borch-Johnsen, K., Jørgensen, T., Madsen, O. D., Lebl, J., Hansen, Torben & Pedersen, Oluf Borbye, 2006, In: Journal of Clinical Endocrinology and Metabolism. 91, 12, p. 5057-63 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Association of the calpain-10 gene with type 2 diabetes in Europeans: results of pooled and meta-analyses

    Tsuchiya, T., Schwarz, P. E. H., Bosque-Plata, L. D., Geoffrey Hayes, M., Dina, C., Froguel, P., Wayne Towers, G., Fischer, S., Temelkova-Kurktschiev, T., Rietzsch, H., Graessler, J., Vcelák, J., Palyzová, D., Selisko, T., Bendlová, B., Schulze, J., Julius, U., Hanefeld, M., Weedon, M. N., Evans, J. C. & 12 others, Frayling, T. M., Hattersley, A. T., Orho-Melander, M., Groop, L., Malecki, M. T., Hansen, Torben, Pedersen, Oluf Borbye, Fingerlin, T. E., Boehnke, M., Hanis, C. L., Cox, N. J. & Bell, G. I., 2006, In: Molecular Genetics and Metabolism. 89, 1-2, p. 174-84 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Biases in the perceived timing of perisaccadic perceptual and motor events

    Yarrow, K., Whiteley, Louise, Haggard, P. & Rothwell, J. C., 2006, In: Attention, Perception & Psychophysics. 68, 7, p. 1217-26 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Body mass, fat-free body mass, and prognosis in patients with chronic obstructive pulmonary disease from a random population sample: findings from the Copenhagen City Heart Study

    Vestbo, J., Prescott, Eva, Almdal, Thomas Peter, Dahl, M., Nordestgaard, Børge, Andersen, T., Sørensen, Thorkild I.A. & Lange, Peter, 2006, In: American Journal of Respiratory and Critical Care Medicine. 173, 1, p. 79-83 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    EIF4A2 is a positional candidate gene at the 3q27 locus linked to type 2 diabetes in French families

    Cheyssac, C., Dina, C., Leprêtre, F., Vasseur-Delannoy, V., Dechaume, A., Lobbens, S., Balkau, B., Ruiz, J., Charpentier, G., Pattou, F., Joly, E., Prentki, M., Hansen, Torben, Pedersen, Oluf Borbye, Vaxillaire, M. & Froguel, P., 2006, In: Diabetes. 55, 4, p. 1171-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Fedmens genetik

    Echwald, S. M., Larsen, P. J., Pedersen, Oluf Borbye & Sørensen, Thorkild I.A., 2006, In: Ugeskrift for læger. 168, 2, p. 150-152 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review