Novo Nordisk Foundation Center for Basic Metabolic Research

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  1. 2005
  2. Published

    Evidence that the mitochondrial leucyl tRNA synthetase (LARS2) gene represents a novel type 2 diabetes susceptibility gene

    hart, L. M., Hansen, Torben, Rietveld, I., Dekker, J. M., Nijpels, G., Janssen, G. M. C., Arp, P. A., Uitterlinden, A. G., Jørgensen, T., Borch-Johnsen, K., Pols, H. A. P., Pedersen, Oluf Borbye, van Duijn, C. M., Heine, R. J. & Maassen, J. A., 2005, In: Diabetes. 54, 6, p. 1892-5 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Genetics of type 2 diabetes mellitus: status and perspectives

    Hansen, L. & Pedersen, Oluf Borbye, 2005, In: Diabetes, Obesity and Metabolism. 7, 2, p. 122-35 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Increased risk of intestinal cancer in Crohn's disease: A meta-analysis of population-based cohort studies

    Jess, T., Gamborg, M., Matzen, P., Munkholm, P. & Sørensen, Thorkild I.A., 2005, In: American Journal of Gastroenterology. 100, p. 1-6

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Mutation analysis of the MCHR1 gene in human obesity

    Wermter, A-K., Reichwald, K., Büch, T., Geller, F., Platzer, C., Huse, K., Hess, C., Remschmidt, H., Gudermann, T., Preibisch, G., Siegfried, W., Goldschmidt, H-P., Li, W-D., Price, R. A., Biebermann, H., Krude, H., Vollmert, C., Wichmann, H-E., Illig, T., Sørensen, T. I. A. & 11 others, Astrup, A., Larsen, L. H., Pedersen, Oluf Borbye, Eberlé, D., Clément, K., Blundell, J., Wabitsch, M., Schäfer, H., Platzer, M., Hinney, A. & Hebebrand, J., 2005, In: European Journal of Endocrinology. 152, 6, p. 851-62 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Mutation analysis of the preproghrelin gene: no association with obesity and type 2 diabetes

    Larsen, L. H., Gjesing, A. P., Sørensen, Thorkild I.A., Hamid, Y. H., Echwald, S. M., Toubro, S., Black, E., Astrup, A., Hansen, Torben & Pedersen, Oluf Borbye, 2005, In: Clinical Biochemistry. 38, 5, p. 420-424 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Preparation of phenyl benzoyl pyrazoles as CRTH2 receptor ligands

    Ulven, Trond, Frimurer, Thomas Michael, Rist, O., Kostenis, E., Hoegberg, T., Receveur, J. & Grimstrup, M., 2005, Patent No. WO 2005/115382 A1

    Research output: Patent

  8. Published

    Preparation of substituted thiazoleacetic acids as CRTH2 receptor ligands

    Ulven, Trond, Frimurer, Thomas Michael, Rist, O., Kostenis, E., Hoegberg, T., Receveur, J. & Grimstrup, M., 2005, Patent No. WO 2005/116001 A1

    Research output: Patent

  9. Published

    Prevalence of mutations and functional analyses of melanocortin 4 receptor variants identified among 750 men with juvenile-onset obesity

    Larsen, L. H., Echwald, S. M., Sørensen, Thorkild I.A., Andersen, T., Wulff, B. S. & Pedersen, Oluf Borbye, 2005, In: The Journal of Clinical Endocrinology & Metabolism. 90, 1, p. 219-224 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Quinazoline compounds and their use in MCH-related disease

    Frimurer, Thomas Michael, Ulven, Trond, Högberg, T., Nørregaard, P. K., Little, P. B., Receveur, J. & Grimstrup, M., 2005, Patent No. WO 2005/123714

    Research output: Patent

  11. Published

    Role of transcription factor KLF11 and its diabetes-associated gene variants in pancreatic beta cell function

    Neve, B., Fernandez-Zapico, M. E., Ashkenazi-Katalan, V., Dina, C., Hamid, Y. H., Joly, E., Vaillant, E., Benmezroua, Y., Durand, E., Bakaher, N., Delannoy, V., Vaxillaire, M., Cook, T., Dallinga-Thie, G. M., Jansen, H., Charles, M-A., Clément, K., Galan, P., Hercberg, S., Helbecque, N. & 7 others, Charpentier, G., Prentki, M., Hansen, Torben, Pedersen, Oluf Borbye, Urrutia, R., Melloul, D. & Froguel, P., 2005, In: Proceedings of the National Academy of Sciences of the United States of America. 102, 13, p. 4807-12 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Studies of relationships between variation of the human G protein-coupled receptor 40 Gene and Type 2 diabetes and insulin release

    Hamid, Y. H., Vissing, H., Holst, Birgitte, Urhammer, S. A., Pyke, C., Hansen, S. K., Glümer, C., Borch-Johnsen, K., Jørgensen, T., Schwartz, Thue W., Pedersen, O. & Hansen, Torben, 2005, In: Diabetic Medicine. 22, 1, p. 74-80 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Studies of variations of the cyclin-dependent kinase inhibitor 1C and the cyclin-dependent kinase 4 genes in relation to type 2 diabetes mellitus and related quantitative traits

    Nielsen, E. D., Hansen, L., Stissing, T., Yanagisawa, K., Borch-Johnsen, K., Poulsen, P., Vaag, Allan, Hansen, Torben & Pedersen, Oluf Borbye, 2005, In: Journal of Molecular Medicine. 83, 5, p. 353-61 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Substituted thiazoleacetic acids as CRTH2 receptor ligands

    Ulven, Trond, Frimurer, Thomas Michael, Rist, Ø., Kostenis, E., Högberg, T., Receveur, J. & Grimstrup, M., 2005, Patent No. WO 2005/116001 A1

    Research output: Patent

  15. Published

    The N363S polymorphism of the glucocorticoid receptor and metabolic syndrome factors in men

    Buemann, B., Black, E., Holst, C., Toubro, S., Echwald, S., Pedersen, Oluf Borbye, Astrup, A. & Sørensen, Thorkild I.A., 2005, In: Obesity Research. 13, 5, p. 862-867 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    The functional Thr130Ile and Val255Met polymorphisms of the hepatocyte nuclear factor-4alpha (HNF4A): gene associations with type 2 diabetes or altered beta-cell function among Danes

    Ek, J., Rose, C. S., Jensen, D. P., Glümer, C., Borch-Johnsen, K., Jørgensen, T., Pedersen, Oluf Borbye & Hansen, Torben, 2005, In: Journal of Clinical Endocrinology and Metabolism. 90, 5, p. 3054-9 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    The prevalence of the metabolic syndrome in a danish population of women with previous gestational diabetes mellitus is three-fold higher than in the general population

    Lauenborg, J., Mathiesen, Elisabeth, Hansen, Torben, Glümer, C., Jørgensen, T., Borch-Johnsen, K., Hornnes, P., Pedersen, Oluf Borbye & Damm, Peter, 2005, In: Journal of Clinical Endocrinology and Metabolism. 90, 7, p. 4004-10 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    alpha 2-AMPK knockout abolishes AICAR but not exercise training-induced GLUT4 and HKII protein expression in mouse skeletal muscle

    Jørgensen, Solvejg, Treebak, Jonas Thue, Viollet, B., Andreelli, F., Schjerling, Peter, Vaulont, S., Wojtaszewski, Jørgen F P & Richter, Erik A., 2005, In: FASEB Journal.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. 2004
  20. Published

    Studies of the Ala/Val98 polymorphism of the hepatocyte nuclear factor-1alpha gene and the relationship to beta-cell function during an OGTT in glucose-tolerant women with and without previous gestational diabetes mellitus

    Lauenborg, J., Damm, Peter, Ek, J., Glümer, C., Jørgensen, Tina, Borch-Johnsen, K., Vestergaard, H., Hornnes, P., Pedersen, Oluf Borbye & Hansen, Torben, Dec 2004, In: Diabetic Medicine. 21, 12, p. 1310-5 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    The potential role of SOCS-3 in the interleukin-1beta-induced desensitization of insulin signaling in pancreatic beta-cells

    Emanuelli, Brice, Glondu, M., Filloux, C., Peraldi, P. & Van Obberghen, E., Dec 2004, In: Diabetes. 53 Suppl 3, p. S97-S103

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Plasma GLP-2 levels and intestinal markers in the juvenile pig during intestinal adaptation: effects of different diet regimens

    Paris, M. C., Fuller, P. J., Carstensen, Bendix, Nagy, E., Taylor, R. G., Sourial, M., Holst, Jens Juul, Hartmann, Bolette & Binesm, J. E., Oct 2004, In: Digestive Diseases and Sciences. 49, 10, p. 1688-95 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Glucagon-like peptide 2 (GLP-2) accelerates the growth of colonic neoplasms in mice

    Thulesen, J., Hartmann, Bolette, Hare, K. J., Kissow, Hannelouise, Ørskov, Cathrine, Holst, Jens Juul & Poulsen, Steen Seier, Aug 2004, In: Gut. 53, 8, p. 1145-1150 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    The independent effect of type 2 diabetes mellitus on ischemic heart disease, stroke, and death: a population-based study of 13,000 men and women with 20 years of follow-up

    Almdal, Thomas Peter, Scharling, H., Jensen, J. S. & drb459, drb459, 12 Jul 2004, In: J A M A Internal Medicine. 164, 13, p. 1422-6 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Characterization of RNA interference in rat PC12 cells: requirement of GERp95

    Thonberg, H., Schéele, Camilla Charlotte Nielsen, Dahlgren, C. & Wahlestedt, C., 11 Jun 2004, In: Molecular Cell Biology Research Communications. 318, 4, p. 927-34 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Transcriptional profiling of extracellular amino acid sensing in Saccharomyces cerevisiae and the role of Stp 1 p and Stp2p

    Eckert-Boulet, N., Nielsen, P. S., Friis, Carsten, Moreira dos Santos, M., Nielsen, J., Kielland-Brandt, M. C. & Regenberg, Birgitte, 1 Jun 2004, In: Yeast. 21, 8, p. 635-648 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Onset of small intestinal atrophy is associated with reduced intestinal blood flow in TPN-fed neonatal piglets

    Niinikoski, H., Stoll, B., Guan, X., Kansagra, K., Lambert, B. D., Stephens, J., Hartmann, Bolette, Holst, Jens Juul & Burrin, D. G., Jun 2004, In: Journal of Nutrition. 134, 6, p. 1467-74 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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