Novo Nordisk Foundation Center for Basic Metabolic Research

Treatment of Active Crohn's Disease With an Ordinary Food-based Diet That Replicates Exclusive Enteral Nutrition

Svolos, V., Hansen, R., Nichols, B., Quince, C., Ijaz, U. Z., Papadopoulou, R. T., Edwards, C. A., Watson, D., Alghamdi, A., Brejnrod, A., Ansalone, C., Duncan, H., Gervais, L., Tayler, R., Salmond, J., Bolognini, D., Klopfleisch, R., Gaya, D. R., Milling, S., Russell, R. K. & 1 others, Gerasimidis, K., 2019, In: Gastroenterology. 156, 5, p. 1354-1367 20 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Trimethylamine-N-Oxide and Renal Complications, Cardiovascular Disease, and Mortality in Individuals with Type 2 Diabetes and Microalbuminuria

Winther, S. A., Øllgaard, J. C., Hansen, T., von Scholten, B. J., Gaede, P., Parving, H., Pedersen, Oluf Borbye & Rossing, Peter, 2019, In: Journal of the American Society of Nephrology. 30, Kidney Week Edition, p. 904 1 p., SA-PO551.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

Two-step derivatization for determination of sugar phosphates in plants by combined reversed phase chromatography/tandem mass spectrometry

Rende, U., Niittylae, T. & Moritz, Thomas, 2019, In: Plant Methods. 15, 10 p., 127.

Research output: Contribution to journal › Journal article › Research › peer-review

Underpowered or negative? A crucial distinction

Dollerup, O. L., Treebak, Jonas Thue & Jessen, N., 2019, In: Diabetologia. 62, 6, p. 1094-1095 2 p.

Research output: Contribution to journal › Comment/debate › Research

Utility of Plasma Concentration of Trimethylamine N-Oxide in Predicting Cardiovascular and Renal Complications in Individuals With Type 1 Diabetes

Winther, S. A., Øllgaard, J. C., Tofte, N., Tarnow, L., Wang, Z., Ahluwalia, T. S., Jorsal, A., Theilade, S., Parving, H., Hansen, T. W., Hazen, S. L., Pedersen, Oluf Borbye & Rossing, Peter, 2019, In: Diabetes Care. 42, 8, p. 1512-1520

Research output: Contribution to journal › Journal article › Research › peer-review

Variations in microbiome composition of sewer biofilms due to ferrous and ferric iron dosing

Kiilerich, B., Brejnrod, A. D., Vollertsen, J. & Kiilerich, P., 2019, In: Cogent Environmental Science. 5

Research output: Contribution to journal › Journal article › Research › peer-review

Voluntary wheel running in the late dark phase ameliorates diet-induced obesity in mice without altering insulin action

Kellezi, Emilie Dalbram, Basse, A. L., Zierath, Juleen R & Treebak, Jonas Thue, 2019, In: Journal of Applied Physiology. 126, 4, p. 993-1005 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

WGS-based telomere length analysis in Dutch family trios implicates stronger maternal inheritance and a role for RRM1 gene

Nersisyan, L., Nikoghosyan, M., Francioli, L. C., Menelaou, A., Pulit, S. L., Elbers, C. C., Kloosterman, W. P., van Setten, J., Nijman, I. J., Renkens, I., de Bakker, P. I. W., van Dijk, F., Neerincx, P. B. T., Deelen, P., Kanterakis, A., Dijkstra, M., Byelas, H., van der Velde, K. J., Platteel, M., Swertz, M. A. & 67 others, Wijmenga, C., Palamara, P. F., Pe'er, I., Ye, K., Lameijer, E., Moed, M. H., Beekman, M., de Craen, A. J. M., Suchiman, H. E. D., Slagboom, P. E., Guryev, V., Abdellaoui, A., Hottenga, J. J., Kattenberg, M., Willemsen, G., Boomsma, D. I., van Leeuwen, E. M., Karssen, L. C., Amin, N., Rivadeneira, F., Isaacs, A., Hofman, A., Uitterlinden, A. G., van Duijn, C. M., van Oven, M., Kayser, M., Vermaat, M., Laros, J. F. J., den Dunnen, J. T., van Enckevort, D., Mei, H., Li, M., Stoneking, M., van Schaik, B. D. C., Bot, J., Marschall, T., Schonhuth, A., Hehir-Kwa, J. Y., Handsaker, R. E., Polak, P., Sohail, M., Vuzman, D., Estrada, K., McCarroll, S. A., Sunyaev, S. R., Hormozdiari, F., Koval, V., Medina-Gomez, C., Oostra, B., Veldink, J. H., van den Berg, L. H., Pitts, S. J., Potluri, S., Sundar, P., Cox, D. R., de Knijff, P., Li, Q., Li, Y., Du, Y., Chen, R., Cao, H., Wang, J., Li, N., Cao, S., Bovenberg, J. A., van Ommen, G. B. & Arakelyan, A., 2019, In: Scientific Reports. 9, 9 p., 18758.

Research output: Contribution to journal › Journal article › Research › peer-review

Which to choose, an oral or an injectable glucagon-like peptide-1 receptor agonist?

Holst, Jens Juul, 2019, In: The Lancet. 394, 10192, p. 4-6

Research output: Contribution to journal › Editorial › Research › peer-review

Birth size and gestational age in opposite-sex twins as compared to same-sex twins: An individual-based pooled analysis of 21 cohorts

Jelenkovic, A., Sund, R., Yokoyama, Y., Hur, Y-M., Ullemar, V., Almqvist, C., Magnusson, P. K. E., Willemsen, G., Bartels, M., van Beijsterveldt, C. E. M., Bogl, L. H., Pietilainen, K. H., Vuoksimaa, E., Ji, F., Ning, F., Pang, Z., Nelson, T. L., Whitfield, K. E., Rebato, E., Llewellyn, C. H. & 38 others, Fisher, A., Bayasgalan, G., Narandalai, D., Bjerregaard-Andersen, M., Beck-Nielsen, H., Sodemann, M., Tarnoki, A. D., Tarnoki, D. L., Ooki, S., Stazi, M. A., Fagnani, C., Brescianini, S., Dubois, L., Boivin, M., Brendgen, M., Dionne, G., Vitaro, F., Cutler, T. L., Hopper, J. L., Krueger, R. F., McGue, M., Pahlen, S., Craig, J. M., Saffery, R., Haworth, C. M. A., Plomin, R., Knafo-Noam, A., Mankuta, D., Abramson, L., Burt, S. A., Klump, K. L., Vlietinck, R. F., Derom, C. A., Loos, Ruth, Boomsma, D. I., Sørensen, Thorkild I.A., Kaprio, J. & Silventoinen, K., 1 Dec 2018, In: Scientific Reports. 8, 1, p. 1-8 8 p., 6300.

Research output: Contribution to journal › Journal article › Research › peer-review

Cohort-wide deep whole genome sequencing and the allelic architecture of complex traits

Gilly, A., Suyeges, D., Kuchenbaecker, K., Pollard, M., Southam, L., Hatzikotoulas, K., Farmaki, A-E., Bjornland, T., Waples, R., Appel, E. V. R., Casalone, E., Melloni, G., Kilian, B., Rayner, N. W., Ntalla, I., Kundu, K., Walter, K., Danesh, J., Butterworth, A., Barroso, I. & 5 others, Tsafantakis, E., Dedoussis, G., Zeggini, E., Moltke, Ida & Zeggini, E., 1 Dec 2018, In: Nature Communications. 9, p. 1-9 4674.

Research output: Contribution to journal › Journal article › Research › peer-review

Reduced GLP-1 Secretion at 30 Minutes After a 75g Oral Glucose Load is Observed in Gestational Diabetes Mellitus: A Prospective Cohort Study

Sukumar, N., Bagias, C., Goljan, I., Weldeselassie, Y., Gharanei, S., Tan, B. K., Holst, Jens Juul & Saravanan, P., 1 Dec 2018, In: Diabetes. 67, 12, p. 2650-2656

Research output: Contribution to journal › Journal article › Research › peer-review

Papio spp. Colon microbiome and its link to obesity in pregnancy

Li, Xuan Ji, Rensing, C., Taylor, W. L., Costelle, C., Brejnrod, A. D., Ferry, R. J. ,. J., Higgins, P. B., Folli, F., Kottapalli, K. R., Hubbard, G. B., Dick, E. J. ,. J., Yooseph, S., Nelson, K. E. & Schlabritz-Loutsevitch, N., Dec 2018, In: Journal of Medical Primatology. 47, 6, p. 393-401

Research output: Contribution to journal › Journal article › Research › peer-review

Determinants of Fasting Hyperglucagonemia in Patients with Type 2 Diabetes and Nondiabetic Control Subjects

Demant, M., Bagger, J. I., Suppli, M. P., Lund, A., Gyldenløve, M., Hansen, K. B., Hare, Kristine Juul, Christensen, Mikkel Bring, Sonne, D. P., Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Dec 2018, In: Metabolic Syndrome and Related Disorders. 16, 10, p. 530-536 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

GLP-1 Is a Coronary Artery Vasodilator in Humans

Clarke, S. J., Giblett, J. P., Yang, L. L., Hubsch, A., Zhao, T., Aetesam-ur-Rahman, M., West, N. E. J., O'Sullivan, M., Figg, N., Bennett, M., Albrechtsen, Nicolai Jacob Wewer, Deacon, Carolyn F., Cheriyan, J. & Hoole, S. P., 20 Nov 2018, In: Journal of the American Heart Association. 7, 22, 14 p., e010321.

Research output: Contribution to journal › Journal article › Research › peer-review

Gestational weight gain charts for different body mass index groups for women in Europe, North America, and Oceania

Santos, S., Eekhout, I., Voerman, E., Gaillard, R., Barros, H., Charles, M-A., Chatzi, L., Chevrier, C., Chrousos, G. P., Corpeleijn, E., Costet, N., Crozier, S., Doyon, M., Eggesbo, M., Fantini, M. P., Farchi, S., Forastiere, F., Gagliardi, L., Georgiu, V., Godfrey, K. M. & 60 others, Gori, D., Grote, V., Hanke, W., Hertz-Picciotto, I., Heude, B., Hivert, M., Hryhorczuk, D., Huang, R., Inskip, H., Jusko, T. A., Karvonen, A. M., Koletzko, B., Kupers, L. K., Lagstrom, H., Lawlor, D. A., Lehmann, I., Lopez-Espinosa, M., Magnus, P., Majewska, R., Makela, J., Manios, Y., McDonald, S. W., Mommers, M., Morgen, C. S., Moschonis, G., Murinova, L., Newnham, J., Nohr, E. A., Nybo Andersen, Anne-Marie, Oken, E., Oostvogels, A. J. J. M., Pac, A., Papadopoulou, E., Pekkanen, J., Pizzi, C., Polanska, K., Porta, D., Richiardi, L., Rifas-Shiman, S. L., Roeleveld, N., Santa-Marina, L., Santos, A. C., Smit, H. A., Sørensen, Thorkild I.A., Standl, M., Stanislawski, M., Stoltenberg, C., Thiering, E., Thijs, C., Torrent, M., Tough, S. C., Trnovec, T., van Gelder, M. M. H. J., van Rossem, L., von Berg, A., Vrijheid, M., Vrijkotte, T. G. M., Zvinchuk, O., van Buuren, S. & Jaddoe, V. W. V., 5 Nov 2018, In: BMC Medicine. 16, 15 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

Ligthart, S., Vaez, A., Vosa, U., Stathopoulou, M. G., de Vries, P. S., Prins, B. P., Van der Most, P. J., Tanaka, T., Naderi, E., Rose, L. M., Wu, Y., Karlsson, R., Barbalic, M., Lin, H., Pool, R., Zhu, G., Mace, A., Sidore, C., Trompet, S., Mangino, M. & 266 others, Sabater-Lleal, M., Kemp, J. P., Abbasi, A., Kacprowski, T., Verweij, N., Smith, A. V., Huang, T., Marzi, C., Feitosa, M. F., Lohman, K. K., Kleber, M. E., Milaneschi, Y., Mueller, C., Huq, M., Vlachopoulou, E., Lyytikainen, L., Oldmeadow, C., Deelen, J., Perola, M., Zhao, J., Feenstra, B., Amini, M., Lahti, J., Schraut, K. E., Fornage, M., Suktitipat, B., Chen, W., Li, X., Nutile, T., Malerba, G., Luan, J., Bak, T., Schork, N., Del Greco, F. M., Thiering, E., Mahajan, A., Marioni, R. E., Mihailov, E., Eriksson, J., Ozel, A. B., Zhang, W., Nethander, M., Cheng, Y., Aslibekyan, S., Ang, W., Gandin, I., Yengo, L., Portas, L., Kooperberg, C., Hofer, E., Rajan, K. B., Schurmann, C., den Hollander, W., Ahluwalia, Tarun Veer Singh, Zhao, J., Draisma, H. H. M., Ford, I., Timpson, N., Teumer, A., Huang, H., Wahl, S., Liu, Y., Huang, J., Uh, H., Geller, F., Joshi, P. K., Yanek, L. R., Trabetti, E., Lehne, B., Vozzi, D., Verbanck, M., Biino, G., Saba, Y., Meulenbelt, I., O'Connell, J. R., Laakso, M., Giulianini, F., Magnusson, P. K. E., Ballantyne, C. M., Hottenga, J. J., Montgomery, G., Rivadineira, F., Rueedi, R., Steri, M., Herzig, K., Stott, D. J., Menni, C., Franberg, M., St Pourcain, B., Felix, S. B., Pers, Tune H, Bakker, S. J. L., Kraft, P., Peters, A., Vaidya, D., Delgado, G., Smit, J. H., Grossmann, V., Sinisalo, J., Seppala, I., Williams, S. R., Holliday, E. G., Moed, M., Langenberg, C., Raikkonen, K., Ding, J., Campbell, H., Sale, M. M., Chen, Y. I., James, A. L., Ruggiero, D., Soranzo, N., Hartman, C. A., Smith, E. N., Berenson, G. S., Fuchsberger, C., Hernandez, D., Tiesler, C. M. T., Giedraitis, V., Liewald, D., Fischer, K., Mellstrom, D., Larsson, A., Wang, Y., Scott, W. R., Lorentzon, M., Beilby, J., Ryan, K. A., Pennell, C. E., Vuckovic, D., Balkau, B., Concas, M. P., Schmidt, R., de Leon, C. F. M., Bottinger, E. P., Kloppenburg, M., Paternoster, L., Boehnke, M., Musk, A. W., Willemsen, G., Evans, D. M., Madden, P. A. F., Kahonen, M., Kutalik, Z., Zoledziewska, M., Karhunen, V., Kritchevsky, S. B., Sattar, N., Lachance, G., Clarke, R., Harris, T. B., Raitakari, O. T., Attia, J. R., Van Heemst, D., Kajantie, E., Sorice, R., Gambaro, G., Scott, R. A., Hicks, A. A., Ferrucci, L., Standl, M., Lindgren, C. M., Starr, J. M., Karlsson, M., Lind, L., Li, J. Z., Chambers, J. C., Mori, T. A., de Geus, E. J. C. N., Heath, A. C., Martin, N. G., Auvinen, J., Buckley, B. M., de Craen, A. J. M., Waldenberger, M., Strauch, K., Meitinger, T., Scott, R. J., McEvoy, M., Beekman, M., Bombieri, C., Ridker, P. M., Mohlke, K. L., Pedersen, N. L., Morrison, A. C., Boomsma, D. I., Whitfield, J. B., Strachan, D. P., Hofman, A., Vollenweider, P., Cucca, F., Jarvelin, M., Jukema, J. W., Spector, T. D., Hamsten, A., Zeller, T., Uitterlinden, A. G., Nauck, M., Gudnason, V., Qi, L., Grallert, H., Borecki, I. B., Rotter, J. I., Maerz, W., Wild, P. S., Lokki, M., Boyle, M., Salomaa, V., Melbye, M., Eriksson, J. G., Wilson, J. F., Penninx, B. W. J. H., Becker, D. M., Worrall, B. B., Gibson, G., Krauss, R. M., Ciullo, M., Zaza, G., Wareham, N. J., Oldehinkel, A. J., Palmer, L. J., Murray, S. S., Pramstaller, P. P., Bandinelli, S., Heinrich, J., Ingelsson, E., Deary, I. J., Magi, R., Vandenput, L., van der Harst, P., Desch, K. C., Kooner, J. S., Ohlsson, C., Hayward, C., Lehtimaki, T., Shuldiner, A. R., Arnett, D. K., Beilin, L. J., Robino, A., Froguel, P., Pirastu, M., Jess, T., Koenig, W., Loos, Ruth, Evans, D. A., Schmidt, H., Smith, G. D., Slagboom, P. E., Eiriksdottir, G., Morris, A. P., Psaty, B. M., Tracy, R. P., Nolte, I. M., Boerwinkle, E., Visvikis-Siest, S., Reiner, A. P., Gross, M., Bis, J. C., Franke, L., Franco, O. H., Benjamin, E. J., Chasman, D. I., Dupuis, J., Snieder, H., Dehghan, A. & Alizadeh, B. Z., 1 Nov 2018, In: American Journal of Human Genetics. 103, 5, p. 691-706

Research output: Contribution to journal › Journal article › Research › peer-review

Elevated arterial lactate delays recovery of intracellular muscle pH after exercise

Volianitis, S., Secher, Niels H. & Quistorff, B., Nov 2018, In: European Journal of Applied Physiology. 118, 11, p. 2429-2434

Research output: Contribution to journal › Journal article › Research › peer-review

Hepatic Insulin Clearance in Regulation of Systemic Insulin Concentrations—Role of Carbohydrate and Energy Availability

Bojsen-Møller, K. N., Lundsgaard, Anne-Marie, Madsbad, Sten, Kiens, Bente & Holst, Jens Juul, Nov 2018, In: Diabetes. 67, 11, p. 2129-2136 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Recovery of gut microbiota of healthy adults following antibiotic exposure

Palleja, A., Mikkelsen, K. H., Forslund, S. K., Kashani, A., Allin, K. H., Nielsen, T., Hansen, T. H., Liang, S., Feng, Q., Zhang, C., Pyl, P. T., Coelho, L. P., Yang, H., Wang, J., Typas, A., Nielsen, M. F., Nielsen, H. B., Bork, P., Wang, J., Vilsbøll, T. & 4 others, Hansen, Torben, Knop, Filip Krag, Arumugam, Mani & Pedersen, Oluf Borbye, Nov 2018, In: Nature Microbiology. 3, 11, p. 1255-1265 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Population-based studies of relationships between dietary acidity load, insulin resistance and incident diabetes in Danes 11 Medical and Health Sciences 1103 Clinical Sciences

Gæde, J., Nielsen, T., Madsen, M. L., Toft, Ulla Marie Nørgaard, Jørgensen, T., Overvad, K., Tjønneland, Anne, Hansen, Torben, Allin, K. H. & Pedersen, Oluf Borbye, 6 Oct 2018, In: Nutrition Journal. 17, 1, 91.

Research output: Contribution to journal › Journal article › Research › peer-review

Change in weight status from childhood to early adulthood and late adulthood risk of colon cancer in men: a population-based cohort study

Jensen, B. W., Bjerregaard, L. G., Ängquist, Lars, Gögenur, Ismail, Renehan, A. G., Osler, Merete, Sørensen, Thorkild I.A. & Baker, J. L., 1 Oct 2018, In: International Journal of Obesity. 42, p. 1797-1803 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Adaptive changes in pancreas post Roux-en-Y gastric bypass induced weight loss

Lautenbach, A., Wernecke, M., Riedel, N., Veigel, J., Yamamura, J., Keller, S., Jung, R., Busch, P., Mann, O., Knop, Filip Krag, Holst, Jens Juul, Meier, J. J. & Aberle, J., Oct 2018, In: Diabetes - Metabolism: Research and Reviews (Print Edition). 34, 7, p. 1-8 e3025.

Research output: Contribution to journal › Journal article › Research › peer-review

Anti-Obesity Therapy: from Rainbow Pills to Polyagonists.

Müller, T., Clemmensen, Christoffer, Finan, B., DiMarchi, R. & Tschöp, M., Oct 2018, In: Pharmacological Reviews.

Research output: Contribution to journal › Journal article › Research › peer-review

The prebiotic inulin improves substrate metabolism and promotes short-chain fatty acid production in overweight to obese men

van der Beek, C. M., Canfora, E. E., Kip, A. M., Gorissen, S. H. M., Damink, S. W. M. O., van Eijk, H. M., Holst, Jens Juul, Blaak, E. E., Dejong, C. H. C. & Lenaerts, K., Oct 2018, In: Metabolism. 87, p. 25-35

Research output: Contribution to journal › Journal article › Research › peer-review

Identification of novel high-impact recessively inherited type 2 diabetes risk variants in the Greenlandic population

Grarup, N., Moltke, Ida, Lepola, Mette Andersen, Bjerregaard, P., Larsen, C. V. L., Dahl-Petersen, I. K., Jørsboe, E., Tiwari, H. K., Hopkins, S. E., Wiener, H. W., Boyer, B. B., Linneberg, Allan René, Pedersen, Oluf Borbye, Jørgensen, M. E., Albrechtsen, Anders & Hansen, Torben, 1 Sep 2018, In: Diabetologia. 61, 9, p. 2005–2015

Research output: Contribution to journal › Journal article › Research › peer-review

Variation in mitochondrial respiratory capacity and myosin heavy chain composition in repeated muscle biopsies

Sahl, Ronni Eg, Morville, T., Kraunsøe, R., Dela, Flemming, Helge, Jørn Wulff & Larsen, Steen, 1 Sep 2018, In: Analytical Biochemistry. 556, p. 119-124 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Neurog3-dependent pancreas dysgenesis causes ectopic pancreas in Hes1 mutant mice

Jørgensen, Mette Christine, de Lichtenberg, K. H., Collin, C. A., Klinck, R., Ekberg, J. H., Engelstoft, M. S., Lickert, H. & Serup, Palle, Sep 2018, In: Development (Cambridge, England). 145, 17, p. 1-11 11 p., dev163568.

Research output: Contribution to journal › Journal article › Research › peer-review

Dairy Intake and Acne Vulgaris: A Systematic Review and Meta-Analysis of 78,529 Children, Adolescents, and Young Adults

Juhl, C. R., Bergholdt, H. K. M., Miller, I. M., Jemec, Gregor, Kanters, Jørgen K. & Ellervik, Christina, 9 Aug 2018, In: Nutrients. 10, 8, 13 p., 1049.

Research output: Contribution to journal › Review › Research › peer-review

Lactase Persistence, Milk Intake, and Adult Acne: A Mendelian Randomization Study of 20,416 Danish Adults

Juhl, C. R., Bergholdt, H. K. M., Miller, I. M., Jemec, Gregor, Kanters, Jørgen K. & Ellervik, Christina, 8 Aug 2018, In: Nutrients. 10, 8, 11 p., 1041.

Research output: Contribution to journal › Journal article › Research › peer-review

The effect of obesity on early fetal growth and pregnancy duration: a cohort study

Thagaard, I. N., Krebs, Lone, Holm, Jens-Christian, Christiansen, M., Møller, H., Lange, Theis & Larsen, T., 4 Aug 2018, In: Journal of Maternal - Fetal & Neonatal Medicine. 31, 22, p. 2941-2946 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

An adult-based insulin resistance genetic risk score associates with insulin resistance, metabolic traits and altered fat distribution in Danish children and adolescents who are overweight or obese

Graae, A. S., Hollensted, M., Kloppenborg, J. T., Mahendran, Y., Schnurr, T. M., Appel, E. V. R., Rask, J., Nielsen, T. R. H., Johansen, M., Linneberg, Allan René, Jørgensen, M. E., Grarup, N., Kadarmideen, H. N., Holst, Birgitte, Pedersen, Oluf Borbye, Holm, Jens-Christian & Hansen, Torben, Aug 2018, In: Diabetologia. 61, 8, p. 1769-1779

Research output: Contribution to journal › Journal article › Research › peer-review

Is glucagon‐like peptide‐1 fully protected by the dipeptidyl peptidase 4 inhibitor sitagliptin when administered to patients with type 2 diabetes?

Andersen, E. S., Lund, A., Bagger, J. I., Andreasen, C., Grøndahl, M., Deacon, Carolyn F., Hartmann, Bolette, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, Aug 2018, In: Diabetes, Obesity and Metabolism. 20, 8, p. 1937-1943

Research output: Contribution to journal › Journal article › Research › peer-review

Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6

Prins, B. P., Mead, T. J., Brody, J. A., Sveinbjornsson, G., Ntalla, I., Bihlmeyer, N. A., van den Berg, M., Bork-Jensen, J., Cappellani, S., Van Duijvenboden, S., Klena, N. T., Gabriel, G. C., Liu, X., Gulec, C., Grarup, N., Haessler, J., Hall, L. M., Iorio, A., Isaacs, A., Li-Gao, R. & 31 others, Lin, H., Liu, C., Lyytikäinen, L., Marten, J., Mei, H., Müller-Nurasyid, M., Orini, M., Padmanabhan, S., Radmanesh, F., Ramirez, J., Robino, A., Schwartz, M., van Setten, J., Smith, A. V., Verweij, N., Warren, H. R., Weiss, S., Alonso, A., Arnar, D. O., Bots, M. L., de Boer, R. A., Dominiczak, A. F., Eijgelsheim, M., Ellinor, P. T., Guo, X., Felix, S. B., Linneberg, Allan René, Pedersen, Oluf Borbye, Hansen, Torben, Kanters, Jørgen K. & et al., E. A., 17 Jul 2018, In: Genome Biology. 19, 17 p., 87.

Research output: Contribution to journal › Journal article › Research › peer-review

Glucose-lowering effects and mechanisms of the bile acid-sequestering resin sevelamer

Brønden, A., Mikkelsen, K., Sonne, D. P., Hansen, M., Våben, C., Gabe, M. N., Rosenkilde, Mette, Tremaroli, V., Wu, H., Bäckhed, F., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Jul 2018, In: Diabetes, Obesity and Metabolism. 20, 7, p. 1623-1631

Research output: Contribution to journal › Journal article › Research › peer-review

Impact of weight loss achieved through a multidisciplinary intervention on appetite in patients with severe obesity

Coutinho, S. R., Rehfeld, Jens Frederik, Holst, Jens Juul, Kulseng, B. & Martins, C., Jul 2018, In: American Journal of Physiology: Endocrinology and Metabolism. 315, 1, p. E91-E98

Research output: Contribution to journal › Journal article › Research › peer-review

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium douglas.ruderfer@vanderbilt.edu, B. D. A. S. W. G. O. T. P. G. C. D. R. E., Psychosis Endophenotypes International Consortium, P. E. I. C. & Wellcome Trust Case-Control Consortium, W. T. C. C., 14 Jun 2018, In: Cell. 173, 7, p. 1705-1715.e16

Research output: Contribution to journal › Journal article › Research › peer-review

Contributions of mean and shape of blood pressure distribution to worldwide trends and variations in raised blood pressure: a pooled analysis of 1018 population-based measurement studies with 88.6 million participants

Zhou, B., Bentham, J., Di Cesare, M., Bixby, H., Danaei, G., Hajifathalian, K., Taddei, C., Carrillo-Larco, R. M., Djalalinia, S., Khatibzadeh, S., Lugero, C., Peykari, N., Zhang, W. Z., Bennett, J., Bilano, V., Stevens, G. A., Cowan, M. J., Riley, L. M., Chen, Z., Hambleton, I. R. & 840 others, Jackson, R. T., Kengne, A. P., Khang, Y., Laxmaiah, A., Liu, J., Malekzadeh, R., Neuhauser, H. K., Soric, M., Starc, G., Sundstrom, J., Woodward, M., Ezzati, M., Abarca-Gomez, L., Abdeen, Z. A., Abu-Rmeileh, N. M., Acosta-Cazares, B., Adams, R. J., Aekplakorn, W., Afsana, K., Aguilar-Salinas, C. A., Agyemang, C., Ahmad, N. A., Ahmadvand, A., Ahrens, W., Ajlouni, K., Akhtaeva, N., Al-Raddadi, R., Ali, M. M., Ali, O., Alkerwi, A., Aly, E., Amarapurkar, D. N., Amouyel, P., Amuzu, A., Andersen, L. B., Anderssen, S. A., Ängquist, Lars, Anjana, R. M., Ansong, D., Aounallah-Skhiri, H., Araujo, J., Ariansen, I., Aris, T., Arlappa, N., Arveiler, D., Aryal, K. K., Aspelund, T., Assah, F. K., Assuncao, M. C. F., Avdicova, M., Azevedo, A., Azizi, F., Babu, B. V., Bahijri, S., Balakrishna, N., Bamoshmoosh, M., Banach, M., Bandosz, P., Banegas, J. R., Barbagallo, C. M., Barcelo, A., Barkat, A., Barros, A. J. D., Barros, M. V., Bata, I., Batieha, A. M., Batyrbek, A., Baur, L. A., Beaglehole, R., Ben Romdhane, H., Benet, M., Benson, L. S., Bernabe-Ortiz, A., Bernotiene, G., Bettiol, H., Bhagyalaxmi, A., Bharadwaj, S., Bhargava, S. K., Bi, Y., Bikbov, M., Bista, B., Bjerregaard, P., Bjertness, E., Bjertness, M. B., Bjorkelund, C., Blokstra, A., Bo, S., Bobak, M., Boeing, H., Boggia, J. G., Boissonnet, C. P., Bongard, V., Borchini, R., Bovet, P., Braeckman, L., Brajkovich, I., Branca, F., Breckenkamp, J., Brenner, H., Brewster, L. M., Bruno, G., Bueno-de-Mesquita, Bugge, A., Burns, C., Bursztyn, M., Cabrera de Leon, A., Cacciottolo, J., Cai, H., Cameron, C., Can, G., Candido, A. P. C., Capuano, V., Cardoso, V. C., Carlsson, A. C., Carvalho, M. J., Casanueva, F. F., Casas, J., Caserta, C. A., Chamukuttan, S., Chan, A. W., Chan, Q., Chaturvedi, H. K., Chaturvedi, N., Chen, C., Chen, F., Chen, H., Chen, S., Chen, Z., Cheng, C., Cherkaoui Dekkaki, I., Chetrit, A., Chiolero, A., Chiou, S., Chirita-Emandi, A., Chirlaque, M., Cho, B., Cho, Y., Christofaro, D. G., Chudek, J., Cifkova, R., Cinteza, E., Claessens, F., Clays, E., Concin, H., Cooper, C., Cooper, R., Coppinger, T. C., Costanzo, S., Cottel, D., Cowell, C., Craig, C. L., Crujeiras, A. B., Cruz, J. J., D'Arrigo, G., d'Orsi, E., Dallongeville, J., Damasceno, A., Danaei, G., Dankner, R., Dantoft, T. M., Dauchet, L., Davletov, K., De Backer, G., De Bacquer, D., de Gaetano, G., De Henauw, S., de Oliveira, P. D., De Smedt, D., Deepa, M., Dehghan, A., Delisle, H., Deschamps, V., Dhana, K., Di Castelnuovo, A. F., Dias-da-Costa, J. S., Diaz, A., Dickerson, T. T., Djalalinia, S., Do, H. T. P., Dobson, A. J., Donfrancesco, C., Donoso, S. P., Doering, A., Dorobantu, M., Doua, K., Drygas, W., Dulskiene, V., Dzakula, A., Dzerve, V., Dziankowska-Zaborszczyk, E., Eggertsen, R., Ekelund, U., El Ati, J., Elliott, P., Elosua, R., Erasmus, R. T., Erem, C., Eriksen, L., Eriksson, J. G., Escobedo-de la Pena, J., Evans, A., Faeh, D., Fall, C. H., Farzadfar, F., Felix-Redondo, F. J., Ferguson, T. S., Fernandes, R. A., Fernandez-Berges, D., Ferrante, D., Ferrari, M., Ferreccio, C., Ferrieres, J., Finn, J. D., Fischer, K., Foger, B., Foo, L. H., Forslund, A., Forsner, M., Fouad, H. M., Francis, D. K., Franco, M. D. C., Franco, O. H., Frontera, G., Fuchs, F. D., Fuchs, S. C., Fujita, Y., Furusawa, T., Gaciong, Z., Galvano, F., Garcia-de-la-Hera, M., Gareta, D., Garnett, S. P., Gaspoz, J., Gasull, M., Gates, L., Geleijnse, J. M., Ghasemian, A., Ghimire, A., Giampaoli, S., Gianfagna, F., Gill, T. K., Giovannelli, J., Goldsmith, R. A., Goncalves, H., Gonzalez-Gross, M., Gonzalez-Rivas, J. P., Bonet Gorbea, M., Gottrand, F., Graff-Iversen, S., Grafnetter, D., Grajda, A., Grammatikopoulou, M. G., Gregor, R. D., Grodzicki, T., Grontved, A., Grosso, G., Gruden, G., Grujic, V., Gu, D., Guan, O. P., Gudmundsson, E. F., Gudnason, V., Guerrero, R., Guessous, I., Guimaraes, A. L., Gulliford, M. C., Gunnlaugsdottir, J., Gunter, M., Gupta, P. C., Gupta, R., Gureje, O., Gurzkowska, B., Gutierrez, L., Gutzwiller, F., Hadaegh, F., Halkjær, J., Hambleton, I. R., Hardy, R., Kumar, R. H., Hata, J., Hayes, A. J., He, J., He, Y., Hendriks, M. E., Henriques, A., Hernandez Cadena, L., Herrala, S., Heshmat, R., Hihtaniemi, I. T., Ho, S. Y., Ho, S. C., Hobbs, M., Hofman, A., Dinc, G. H., Horimoto, A. R. V. R., Hormiga, C. M., Horta, B. L., Houti, L., Howitt, C., Htay, T. T., Htet, A. S., Htike, M. M. T., Hu, Y., Maria Huerta, J., Huisman, M., Husseini, A. S., Huybrechts, I., Hwalla, N., Iacoviello, L., Iannone, A. G., Ibrahim, M. M., Wong, N. I., Ikeda, N., Ikram, M. A., Irazola, V. E., Islam, M., Ismail, A. A., Ivkovic, V., Iwasaki, M., Jackson, R. T., Jacobs, J. M., Jaddou, H., Jafar, T., Jamrozik, K., Janszky, I., Jasienska, G., Jelakovic, A., Jelakovic, B., Jennings, G., Jeong, S., Jiang, C. Q., Joffres, M., Johansson, M., Jokelainen, J. J., Jonas, J. B., Jorgensen, T., Joshi, P., Jozwiak, J., Juolevi, A., Jurak, G., Juresa, V., Kaaks, R., Kafatos, A., Kajantie, E. O., Kalter-Leibovici, O., Kamaruddin, N. A., Karki, K. B., Kasaeian, A., Katz, J., Kauhanen, J., Kaur, P., Kavousi, M., Kazakbaeva, G., Keil, U., Boker, L. K., Keinanen-Kiukaanniemi, S., Kelishadi, R., Kemper, H. C. G., Kengne, A. P., Kerimkulova, A., Kersting, M., Key, T., Khader, Y. S., Khalili, D., Khang, Y., Khateeb, M., Khaw, K., Kiechl-Kohlendorfer, U., Kiechl, S., Killewo, J., Kim, J., Kim, Y., Klumbiene, J., Knoflach, M., Kolle, E., Kolsteren, P., Korrovits, P., Koskinen, S., Kouda, K., Kowlessur, S., Koziel, S., Kriemler, S., Kristensen, P. L., Krokstad, S., Kromhout, D., Kruger, H. S., Kubinova, R., Kuciene, R., Kuh, D., Kujala, U. M., Kulaga, Z., Kumar, R. K., Kurjata, P., Kusuma, Y. S., Kuulasmaa, K., Kyobutungi, C., Laatikainen, T., Lachat, C., Lam, T. H., Landrove, O., Lanska, V., Lappas, G., Larijani, B., Laugsand, L. E., Laxmaiah, A., Khanh Le Nguyen Bao, Le, T. D., Leclercq, C., Lee, J., Lee, J., Lehtimaki, T., Leon-Munoz, L. M., Levitt, N. S., Li, Y., Lilly, C. L., Lim, W., Fernanda Lima-Costa, M., Lin, H., Lin, X., Lind, L., Linneberg, Allan René, Lissner, L., Litwin, M., Liu, J., Lorbeer, R., Lotufo, P. A., Eugenio Lozano, J., Luksiene, D., Lundqvist, A., Lunet, N., Lytsy, P., Ma, J., Machado-Coelho, G. L. L., Machi, S., Maggi, S., Magliano, D. J., Magriplis, E., Majer, M., Makdisse, M., Malekzadeh, R., Malhotra, R., Rao, K. M., Malyutina, S., Manios, Y., Mann, J. I., Manzato, E., Margozzini, P., Marques-Vidal, P., Marques, L. P., Marrugat, J., Martorell, R., Mathiesen, E. B., Matijasevich, A., Matsha, T. E., Mbanya, J. C. N., Posso, A. J. M. D., McFarlane, S. R., McGarvey, S. T., McLachlan, S., McLean, R. M., McLean, S. B., McNulty, B. A., Mediene-Benchekor, S., Medzioniene, J., Meirhaeghe, A., Meisinger, C., Menezes, A. M. B., Menon, G. R., Meshram, I. I., Metspalu, A., Meyer, H. E., Mi, J., Mikkel, K., Miller, J. C., Minderico, C. S., Francisco, J., Jaime Miranda, J., Mirrakhimov, E., Misigoj-Durakovic, M., Modesti, P. A., Mohamed, M. K., Mohammad, K., Mohammadifard, N., Mohan, V., Mohanna, S., Yusoff, M. F. M., Mollehave, L. T., Moller, N. C., Molnar, D., Momenan, A., Mondo, C. K., Monyeki, K. D. K., Moon, J. S., Moreira, L. B., Morejon, A., Moreno, L. A., Morgan, K., Moschonis, G., Mossakowska, M., Mostafa, A., Mota, J., Motlagh, M. E., Motta, J., Msyamboza, K. P., Mu, T. T., Muiesan, M. L., Mueller-Nurasyid, M., Murphy, N., Mursu, J., Musil, V., Nabipour, I., Nagel, G., Naidu, B. M., Nakamura, H., Namesna, J., Nang, E. E. K., Nangia, V. B., Narake, S., Nauck, M., Maria Navarrete-Munoz, E., Ndiaye, N. C., Neal, W. A., Nenko, I., Neovius, M., Nervi, F., Neuhauser, H. K., Nguyen, C. T., Nguyen, D. N., Quang Ngoc Nguyen, Nguyen, Q. V., Nieto-Martinez, R. E., Niiranen, T. J., Ning, G., Ninomiya, T., Nishtar, S., Noale, M., Noboa, O. A., Noorbala, A. A., Norat, T., Noto, D., Al Nsour, M., O'Reilly, D., Oda, E., Oehlers, G., Oh, K., Ohara, K., Olinto, M. T. A., Oliveira, I. O., Azahadi, M., Onat, A., Ong, S. K., Ono, L. M., Ordunez, P., Ornelas, R., Osmond, C., Ostojic, S. M., Ostovar, A., Otero, J. A., Overvad, K., Owusu-Dabo, E., Paccaud, F. M., Padez, C., Pahomova, E., Pajak, A., Palli, D., Palmieri, L., Pan, W., Panda-Jonas, S., Panza, F., Papandreou, D., Park, S., Parnell, W. R., Parsaeian, M., Patel, N. D., Pecin, I., Pednekar, M. S., Peer, N., Peeters, P. H., Peixoto, S. V., Peltonen, M., Pereira, A. C., Peters, A., Petersmann, A., Petkeviciene, J., Peykari, N., Son Thai Pham, Pigeot, I., Pikhart, H., Pilav, A., Pilotto, L., Pitakaka, F., Piwonska, A., Plans-Rubio, P., Polasek, O., Porta, M., Portegies, M. L. P., Pourshams, A., Poustchi, H., Pradeepa, R., Prashant, M., Price, J. F., Puder, J. J., Puiu, M., Punab, M., Qasrawi, R. F., Qorbani, M., Tran Quoc Bao, Radic, I., Radisauskas, R., Rahman, M., Raitakari, O., Raj, M., Rao, S. R., Ramachandran, A., Ramos, E., Rampal, L., Rampal, S., Reina, D. A. R., Redon, J., Reganit, P. F. M., Ribeiro, R., Riboli, E., Rigo, F., de Wit, T. F. R., Ritti-Dias, R. M., Robinson, S. M., Robitaille, C., Rodriguez-Artalejo, F., del Cristo Rodriguez-Perez, M., Rodriguez-Villamizar, L. A., Rojas-Martinez, R., Romaguera, D., Ronkainen, K., Rosengren, A., Roy, J. G. R., Rubinstein, A., Sandra Ruiz-Betancourt, B., Rutkowski, M., Sabanayagam, C., Sachdev, H. S., Saidi, O., Sakarya, S., Salanave, B., Salazar Martinez, E., Salmeron, D., Salomaa, V., Salonen, J. T., Salvetti, M., Sanchez-Abanto, J., Sans, S., Santos, D. A., Santos, I. S., dos Santos, R. N., Santos, R., Saramies, J. L., Sardinha, L. B., Sarganas, G., Sarrafzadegan, N., Saum, K., Savva, S., Scazufca, M., Schargrodsky, H., Schipf, S., Schmidt, C. O., Schoettker, B., Schultsz, C., Schutte, A. E., Sein, A. A., Sen, A., Senbanjo, I. O., Sepanlou, S. G., Sharma, S. K., Shaw, J. E., Shibuya, K., Shin, D. W., Shin, Y., Si-Ramlee, K., Siantar, R., Sibai, A. M., Santos Silva, D. A., Simon, M., Simons, J., Simons, L. A., Sjostrom, M., Skovbjerg, S., Slowikowska-Hilczer, J., Slusarczyk, P., Smeeth, L., Smith, M. C., Snijder, M. B., So, H., Sobngwi, E., Soderberg, S., Solfrizzi, V., Sonestedt, E., Song, Y., Sørensen, Thorkild I.A., Soric, M., Jerome, C. S., Soumare, A., Staessen, J. A., Starc, G., Stathopoulou, M. G., Stavreski, B., Steene-Johannessen, J., Stehle, P., Stein, A. D., Stergiou, G. S., Stessman, J., Stieber, J., Stoeckl, D., Stocks, T., Stokwiszewski, J., Stronks, K., Strufaldi, M. W., Sun, C., Sundstrom, J., Sung, Y., Suriyawongpaisal, P., Sy, R. G., Tai, E. S., Tammesoo, M., Tamosiunas, A., Tan, E. J., Tang, X., Tanser, F., Tao, Y., Tarawneh, M. R., Tarqui-Mamani, C. B., Tautu, O., Taylor, A., Theobald, H., Theodoridis, X., Thijs, L., Thuesen, B. H., Tjønneland, A., Tolonen, H. K., Tolstrup, J. S., Topbas, M., Topor-Madry, R., Jose Tormo, M., Torrent, M., Traissac, P., Trichopoulos, D., Trichopoulou, A., Trinh, O. T. H., Trivedi, A., Tshepo, L., Tulloch-Reid, M. K., Tullu, F., Tuomainen, T., Tuomilehto, J., Turley, M. L., Tynelius, P., Tzourio, C., Ueda, P., Ugel, E. E., Ulmer, H., Uusitalo, H. M. T., Valdivia, G., Valvi, D., van der Schouw, Y. T., Van Herck, K., Hoang Van Minh, van Rossem, L., Van Schoor, N. M., van Valkengoed, I. G. M., Vanderschueren, D., Vanuzzo, D., Vatten, L., Vega, T., Velasquez-Melendez, G., Veronesi, G., Verschuren, W. M. M., Verstraeten, R., Victora, C. G., Viet, L., Viikari-Juntura, E., Vineis, P., Vioque, J., Virtanen, J. K., Visvikis-Siest, S., Viswanathan, B., Vlasoff, T., Vollenweider, P., Voutilainen, S., Wade, A. N., Wagner, A., Walton, J., Bebakar, W. M. W., Mohamud, W. N. W., Wanderley, R. S. ,. J., Wang, M., Wang, Q., Wang, Y. X., Wang, Y., Wannamethee, S. G., Wareham, N., Wedderkopp, N., Weerasekera, D., Whincup, P. H., Widhalm, K., Widyahening, I. S., Wiecek, A., Wijga, A. H., Wilks, R. J., Willeit, J., Willeit, P., Williams, E. A., Wilsgaard, T., Wojtyniak, B., Wong-McClure, R. A., Wong, J. Y. Y., Wong, T. Y., Woo, J., Woodward, M., Wu, A. G., Wu, F. C., Wu, S., Xu, H., Yan, W., Yang, X., Ye, X., Yiallouros, P. K., Yoshihara, A., Younger-Coleman, N. O., Yusoff, A. F., Zainuddin, A. A., Zambon, S., Zampelas, A., Zdrojewski, T., Zeng, Y., Zhao, D., Zhao, W., Zheng, W., Zheng, Y., Zhu, D., Zhussupov, B., Zimmermann, E. & Cisneros, J. Z., Jun 2018, In: International Journal of Epidemiology. 47, 3, p. 872-883 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Effects of Smoking Versus Nonsmoking on Postprandial Glucose Metabolism in Heavy Smokers Compared With Nonsmokers

Grøndahl, M. F., Bagger, J. I., Lund, A., Faurschou, A., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Jun 2018, In: Diabetes Care. 41, 6, p. 1260-1267

Research output: Contribution to journal › Journal article › Research › peer-review

Ghrelin secretion in humans - a role for the vagus nerve?

Veedfald, Simon, Plamboeck, A., Hartmann, Bolette, Vilsbøll, Tina, Knop, Filip Krag, Deacon, Carolyn F., Svendsen, Lars Bo & Holst, Jens Juul, Jun 2018, In: Neurogastroenterology and Motility. 30, 6, e13295.

Research output: Contribution to journal › Journal article › Research › peer-review

Neuropeptide Y is Up-regulated and Induces Antinociception in Cancer-induced Bone Pain.

Diaz del Castillo, M., Christiansen, S. H., Appel, C., Falk, S., Woldbye, David Paul Drucker & Heegaard, Anne-Marie, 29 May 2018, In: Neuroscience. 384, p. 111-119

Research output: Contribution to journal › Journal article › Research › peer-review

BMI at school age and incident asthma admissions in early adulthood: A prospective study of 310,211 children

Ulrik, Charlotte Suppli, Lophaven, S. N., Andersen, Zorana Jovanovic, Sørensen, Thorkild I.A. & Baker, J. L., 25 May 2018, In: Clinical Epidemiology. 10, p. 605-612 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Gestational diabetes is associated with change in the gut microbiota composition in third trimester of pregnancy and postpartum

Crusell, Mie Korslund Wiinblad, Hansen, T. H., Nielsen, T., Allin, K. H., Rühlemann, M. C., Damm, Peter, drb459, drb459, Rørbye, Christina, Jørgensen, N. R., Christiansen, O. B., Heinsen, F., Franke, A., Hansen, Torben, Lauenborg, J. & Pedersen, Oluf Borbye, 15 May 2018, In: Microbiome. 6, 19 p., 89.

Research output: Contribution to journal › Journal article › Research › peer-review

G9a regulates temporal preimplantation developmental program and lineage segregation in blastocyst

Zylicz, Jan Jakub, Borensztein, M., Wong, F. C. K., Huang, Yun, Lee, C., Dietmann, S. & Surani, M. A., 10 May 2018, In: eLife. 7, e33361.

Research output: Contribution to journal › Journal article › Research › peer-review

Stimulation of the Bile Acid Receptor Tgr5 Promotes Intestinal Growth

Dal, Jenna Elizabeth Hunt, Hartmann, Bolette, Ullmer, C., Holst, Jens Juul & Kissow, Hannelouise, 1 May 2018, In: Gastroenterology. 154, 6 (S1), 1 p., S-333.

Research output: Contribution to journal › Conference abstract in journal › Research

Impaired fasting glucose and the metabolic profile in Danish children and adolescents with normal weight, overweight, or obesity

Kloppenborg, J. T., Fonvig, Cilius Esmann, Nielsen, T. R. H., Mollerup, P. M., Bøjsøe, C., Pedersen, Oluf Borbye, Johannesen, Jesper, Hansen, Torben & Holm, Jens-Christian, May 2018, In: Pediatric Diabetes. 19, 3, p. 356-365

Research output: Contribution to journal › Journal article › Research › peer-review

Mechanisms in bariatric surgery: Gut hormones, diabetes resolution, and weight loss

Holst, Jens Juul, Madsbad, Sten, Bojsen-Møller, K. N., Svane, M. S., Jørgensen, N. B., Dirksen, C. & Martinussen, C., May 2018, In: Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery. 14, 5, p. 708-714 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

NAMPT-mediated NAD+ biosynthesis is indispensable for adipose tissue plasticity and development of obesity

Nielsen, K. N., Peics, J., Ma, Tao, Karavaeva, Iuliia, Dall, M., Chubanava, Sabina, Basse, A. L., Dmytriyeva, O., Treebak, Jonas Thue & Gerhart-Hines, Zach, May 2018, In: Molecular Metabolism. 11, p. 178-188 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Bidirectional GPR119 agonism requires peptide YY and glucose for activity in mouse and human colon mucosa

Tough, I. R., Forbes, S., Herzog, H., Jones, R. M., Schwartz, Thue W. & Cox, H. M., 1 Apr 2018, In: Endocrinology. 159, 4, p. 1704-1717

Research output: Contribution to journal › Journal article › Research › peer-review

Prenatal risk factors influencing childhood BMI and overweight independent of birth weight and infancy BMI: a path analysis within the Danish National Birth Cohort

Morgen, C. S., Ängquist, Lars, Baker, J. L., Andersen, A., Michaelsen, Kim F. & Sørensen, Thorkild I.A., 1 Apr 2018, In: International Journal of Obesity. 42, 4, p. 594-602 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Aberrant intestinal microbiota in individuals with prediabetes

Allin, K. H., Tremaroli, V., Caesar, R., Jensen, Benjamin Anderschou Holbech, Damgaard, Mads Vargas, Bahl, M. I., Licht, T. R., Hansen, T. H., Nielsen, T., Dantoft, T. M., Linneberg, Allan René, Jørgensen, T., drb459, drb459, Kristiansen, Karsten, Franks, P. W., IMI-DIRECT consortium, I. C., Hansen, Torben, Bäckhed, G. F. & Pedersen, Oluf Borbye, Apr 2018, In: Diabetologia. 61, 4, p. 810-820 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

Mahajan, A., Wessel, J., Willems, S. M., Zhao, W., Robertson, N. R., Chu, A. Y., Gan, W., Kitajima, H., Taliun, D., Rayner, N. W., Guo, X., Lu, Y., Li, M., Jensen, R. A., Hu, Y., Huo, S., Lohman, K. K., Zhang, W., Cook, J. P., Prins, B. P. & 32 others, Flannick, J., Grarup, N., Trubetskoy, V. V., Kravic, J., Kim, Y. J., Rybin, D. V., Yaghootkar, H., Müller-Nurasyid, M., Meidtner, K., Li-Gao, R., Varga, T. V., Marten, J., Li, J., Afzal, Shoaib, Bork-Jensen, J., Tybjærg-Hansen, Anne, Jørgensen, M. E., Jørgensen, T., Kovacs, P., Linneberg, Allan René, Liu, J., Nielsen, S. F., Rode, L., Witte, D. R., Hansen, Torben, Karpe, F., Lind, L., Loos, R. J. F., Nordestgaard, Børge, Pedersen, Oluf Borbye, ExomeBP Consortium, E. C. & V Varga, Tibor, Apr 2018, In: Nature Genetics. 50, 4, p. 559-571 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Impact of a multifactorial treatment programme on clinical outcomes and cardiovascular risk estimates: a retrospective cohort study from a specialised diabetes centre in Denmark

Safai, N., Carstensen, Bendix, drb459, drb459 & Ridderstråle, M., 1 Mar 2018, In: BMJ Open. 8, 3, e019214.

Research output: Contribution to journal › Journal article › Research › peer-review

The association of IgA deficiency on infection rate, self-perceived health, and levels of C-reactive protein in healthy blood donors

Hauge, S. C., Jensen, C. K., Nielsen, L. K., Pedersen, Oluf Borbye, Sørensen, E., Thørner, L. W., Hjalgrim, H., Erikstrup, C., Nielsen, K. R., Kaspersen, K. A., Didriksen, Maria, Dziegiel, Morten Hanefeld & Ullum, H., 1 Mar 2018, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 126, 3, p. 248-256 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Childhood Stature and Growth in Relation to First Ischemic Stroke or Intracerebral Hemorrhage

Gjærde, L. K., Truelsen, T. C. & Baker, J. L., Mar 2018, In: Stroke. 49, 3, p. 579-585

Research output: Contribution to journal › Journal article › Research › peer-review

Childhood body mass index in relation to subsequent risk of type 1 diabetes-A Danish cohort study

Antvorskov, J. C., Aunsholt, L., Buschard, K., Gamborg, Michael Orland, Kristensen, K., Johannesen, Jesper, Sørensen, Thorkild I.A. & Svensson, Jannet, Mar 2018, In: Pediatric Diabetes. 19, 2, p. 265-270 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Effects of a diet rich in arabinoxylan and resistant starch compared with a diet rich in refined carbohydrates on postprandial metabolism and features of the metabolic syndrome

Schioldan, A. G., Gregersen, S., Hald, S., Bjørnshave, A., Bohl, M., Hartmann, Bolette, Holst, Jens Juul, Stødkilde-Jørgensen, H. & Hermansen, K., Mar 2018, In: European Journal of Nutrition. 57, 2, p. 795–807

Research output: Contribution to journal › Journal article › Research › peer-review

Effects of glucagon-like peptide-1 receptor agonists on cardiovascular risk factors: A narrative review of head-to-head comparisons

Dalsgaard, N. B., Vilsbøll, Tina & Knop, Filip Krag, Mar 2018, In: Diabetes, Obesity and Metabolism. 20, 3, p. 508-519

Research output: Contribution to journal › Review › Research › peer-review

Guanylin and uroguanylin mRNA expression is increased following Roux-en-Y gastric bypass, but guanylins do not play a significant role in body weight regulation and glycemic control

Fernandez-Cachon, M. L., Pedersen, S. L., Rigbolt, K. T., Zhang, C., Fabricius, K., Hansen, H. H., Elster, L., Fink, L. N., Schäfer, M., Rhee, N. A., Langholz, E., Wandall, E., Friis, S. U., Vilmann, P., Kristiansen, V. B., Schmidt, C., Schreiter, K., Breitschopf, K., Hübschle, T., Jorsal, T. & 6 others, Vilsbøll, Tina, Schmidt, T., Theis, S., Knop, Filip Krag, Larsen, P. J. & Jelsing, J., Mar 2018, In: Peptides. 101, p. 32-43 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Kynurenic Acid and Gpr35 Regulate Adipose Tissue Energy Homeostasis and Inflammation

Agudelo, L. Z., Ferreira, D. M. S., Cervenka, I., Bryzgalova, G., Dadvar, S., Jannig, P. R., Pettersson-Klein, A. T., Lakshmikanth, T., Sustarsic, E. G., Porsmyr-Palmertz, M., Correia, J. C., Izadi, M., Martínez-Redondo, V., Ueland, P. M., Midttun, Ø., Gerhart-Hines, Zach, Brodin, P., Pereira, T., Berggren, P. & Ruas, J. L., 6 Feb 2018, In: Cell Metabolism. 27, 2, p. 378-392.e5

Research output: Contribution to journal › Journal article › Research › peer-review

Enteroendocrine K and L cells in healthy and type 2 diabetic individuals

Jorsal, T., Rhee, N. A., Pedersen, Jens, Wahlgren, C. D., Mortensen, B., Jepsen, Sara Lind, Jelsing, J., Dalbøge, L. S., Vilmann, Peter, Hassan, H., Hendel, J. W., Poulsen, Steen Seier, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 1 Feb 2018, In: Diabetologia. 61, 2, p. 284-294 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Gastrointestinal Motility in Patients with End-Stage Renal Diease on Chronic Hemodialysis

Broberg, B., Madsen, J., Fuglsang, S., Holst, Jens Juul, Christensen, Karl Bang, Rydahl, C., Idorn, T., Feldt-Rasmussen, Bo & Hornum, Mads, 1 Feb 2018, In: Nephrology Dialysis Transplantation. 33, Supplement 1, p. 318 1 p., SaO009 .

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

The bile acid-sequestering resin sevelamer eliminates the acute GLP-1 stimulatory effect of endogenously released bile acids in patients with type 2 diabetes

Brønden, A., Albér, A., Rohde, U., Gasbjerg, Lærke Smidt, Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 1 Feb 2018, In: Diabetes, Obesity and Metabolism. 20, 2, p. 362-369

Research output: Contribution to journal › Journal article › Research › peer-review

A review of dipeptidyl peptidase-4 inhibitors: Hot topics from randomized controlled trials

Deacon, Carolyn F., Feb 2018, In: Diabetes, Obesity and Metabolism. 20, p. 34-46 13 p.

Research output: Contribution to journal › Review › Research › peer-review

GIP(3-30)NH₂ is an efficacious GIP receptor antagonist in humans: a randomised, double-blinded, placebo-controlled, crossover study

Gasbjerg, Lærke Smidt, Christensen, Mikkel Bring, Hartmann, Bolette, Lanng, A. R., wbf943, wbf943, Gabe, M. B. N., Dela, Flemming, Vilsbøll, Tina, Holst, Jens Juul, Rosenkilde, Mette & Knop, Filip Krag, Feb 2018, In: Diabetologia. 61, 2, p. 413-423

Research output: Contribution to journal › Journal article › Research › peer-review

Glucose-dependent insulinotropic polypeptide (GIP) receptor antagonists as anti-diabetic agents

Gasbjerg, Lærke Smidt, Gabe, M. B. N., Hartmann, Bolette, Christensen, Mikkel Bring, Knop, Filip Krag, Holst, Jens Juul & Rosenkilde, Mette, Feb 2018, In: Peptides. 100, p. 173-181

Research output: Contribution to journal › Journal article › Research › peer-review

Peptide degradation and the role of DPP-4 inhibitors in the treatment of type 2 diabetes

Deacon, Carolyn F., Feb 2018, In: Peptides. 100, p. 150-157 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Predicting albuminuria response to spironolactone treatment with urinary proteomics in patients with type 2 diabetes and hypertension

Lindhardt, M., Persson, F., Oxlund, C., Jacobsen, I. A., Zürbig, P., Mischak, H., Rossing, Peter & Heerspink, H. J. L., Feb 2018, In: Nephrology, Dialysis, Transplantation. 33, 2, p. 296-303 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Soil bacteria show different tolerance ranges to an unprecedented disturbance

Nunes, I. M., Jurburg, S., Jacquiod, S. J. A., Brejnrod, A. D., Falcão Salles, J., Priemé, Anders & Sørensen, Søren Johannes, Feb 2018, In: Biology and Fertility of Soils. 54, 2, p. 189–202 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Human GIP(3-30)NH inhibits G protein-dependent as well as G protein-independent signaling and is selective for the GIP receptor with high-affinity binding to primate but not rodent GIP receptors

Gabe, M. B. N., Sparre-Ulrich, A. H., Pedersen, M. F., Gasbjerg, Lærke Smidt, Inoue, A., Bräuner, Hans, Hartmann, Bolette & Rosenkilde, M. M., 31 Jan 2018, In: Biochemical Pharmacology. 150, p. 97-107 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Obesity is associated with vitamin D deficiency in Danish children and adolescents

Plesner, J. L., Dahl, M., Fonvig, Cilius Esmann, Nielsen, T. R. H., Kloppenborg, J. T., Pedersen, Oluf Borbye, Hansen, Torben & Holm, Jens-Christian, 26 Jan 2018, In: Journal of Pediatric Endocrinology and Metabolism. 31, 1, p. 53-61 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes

Bonàs-Guarch, S., Guindo-Martínez, M., Miguel-Escalada, I., Grarup, N., Sebastian, D., Rodriguez-Fos, E., Sánchez, F., Planas-Fèlix, M., Cortes-Sánchez, P., González, S., Timshel, P., Pers, T. H., Morgan, C. C., Moran, I., Atla, G., González, J. R., Puiggros, M., Martí, J., Andersson, E. A., Díaz, C. & 23 others, Badia, R. M., Udler, M., Leong, A., Kaur, V., Flannick, J., Jørgensen, T., Linneberg, Allan René, Jørgensen, M. E., Witte, D. R., Christensen, C., Brandslund, I., Appel, E. V., Scott, R. A., Luan, J., Langenberg, C., Wareham, N. J., Pedersen, Oluf Borbye, Zorzano, A., Florez, J. C., Hansen, Torben, Ferrer, J., Mercader, J. M. & Torrents, D., 22 Jan 2018, In: Nature Communications. 9, 14 p., 321.

Research output: Contribution to journal › Journal article › Research › peer-review

Lysine demethylase inhibition protects pancreatic β cells from apoptosis and improves β-cell function

Backe, M. B., Andersson, J. L., Bacos, K., Christensen, D. P., Hansen, J. B., Dorosz, J. J., Gajhede, Michael, Dahlby, T., Bysani, M., Kristensen, L. H., Ling, C., Olsen, L. & Mandrup-Poulsen, Thomas, 15 Jan 2018, In: Molecular and Cellular Endocrinology. 460, p. 47-56 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Brown Fat AKT2 Is a Cold-Induced Kinase that Stimulates ChREBP-Mediated De Novo Lipogenesis to Optimize Fuel Storage and Thermogenesis

Sanchez-Gurmaches, J., Tang, Y., Jespersen, N. Z., Wallace, M., Martinez Calejman, C., Gujja, S., Li, H., Edwards, Y. J. K., Wolfrum, C., Metallo, C. M., Nielsen, S., Schéele, Camilla Charlotte Nielsen & Guertin, D. A., 9 Jan 2018, In: Cell Metabolism. 27, 1, p. 195-209.e6

Research output: Contribution to journal › Journal article › Research › peer-review

The Apolipoprotein M/S1P Axis Controls Triglyceride Metabolism and Brown Fat Activity

Christoffersen, Christina, Federspiel, C. K., Borup, A., Christensen, P. M., Madsen, A. N., Heine, M., Nielsen, C. H., Kjaer, A., Holst, Birgitte, Heeren, J. & Nielsen, L. B., 2 Jan 2018, In: Cell Reports. 22, 1, p. 175-188

Research output: Contribution to journal › Journal article › Research › peer-review

Glucose-Dependent Insulinotropic Polypeptide (GIP) Inhibits Bone Resorption Independently of Insulin and Glycemia

Christensen, Mikkel Bring, Lund, A., Calanna, S., Jørgensen, Niklas Rye, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 1 Jan 2018, In: The Journal of clinical endocrinology and metabolism. 103, 1, p. 288-294

Research output: Contribution to journal › Journal article › Research › peer-review

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

Turcot, V., Lu, Y., Highland, H. M., Bang, L. E., Benn, M., Kamstrup, P. R., Bork-Jensen, J., Frikke-Schmidt, R., Gjesing, A. P., Grarup, N., Hansen, T., Have, C. T., Jørgensen, T., Nielsen, S. F., Linneberg, A. R., Pedersen, O., Pers, T. H., Vestergaard, H., Nordestgaard, B., Tybjærg-Hansen, A. & 15 others, Varbo, A., CHD Exome+ Consortium, C. E. C., EPIC-CVD Consortium, E. C., ExomeBP Consortium, E. C., Global Lipids Genetics Consortium, G. L. G. C., GoT2D Genes Consortium, G. G. C., EPIC-InterAct Consortium, E. C., INTERVAL Study, I. S., ReproGen Consortium, R. C., T2D-Genes Consortium, T. C., The MAGIC Investigators, T. M. I., Understanding Society Scientific Group, U. S. S. G., Lindgren, C. M., Hirschhorn, J. N. & Loos, R. J. F., 1 Jan 2018, In: Nature Genetics. 50, p. 26-41 16 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Effect of liraglutide on ectopic fat in polycystic ovary syndrome: A randomized clinical trial

Frøssing, S., Nylander, M., Chabanova, E., Frystyk, J., Holst, Jens Juul, Kistorp, Caroline Michaela Nervil, Skouby, Sven O. & Faber, Jens, Jan 2018, In: Diabetes, Obesity and Metabolism. 20, 1, p. 215-218

Research output: Contribution to journal › Journal article › Research › peer-review

Hidradenitis suppurativa and electrocardiographic changes: a cross‐sectional population study

Juhl, C. R., Miller, I. M., Jemec, Gregor, Kanters, Jørgen K. & Ellervik, Christina, Jan 2018, In: British Journal of Dermatology. 178, 1, p. 222-228

Research output: Contribution to journal › Journal article › Research › peer-review

23, 22 Calling the Microbiota to Control Atherosclerosis

Carreras, A. & Bäckhed, F., 2018, In: Immunity. 49, 5, p. 788-790 3 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Mind the Gut-displaying microbiome research through artistic collaboration

Bencard, Adam & Whiteley, Louise, 2018, In: Microbial Ecology in Health and Disease. 29, 2, 8 p., 1555433.

Research output: Contribution to journal › Journal article › Research › peer-review

In Vitro Community Synergy between Bacterial Soil Isolates Can Be Facilitated by pH Stabilization of the Environment

Herschend, J., Koren, K., Røder, Henriette Lyng, Brejnrod, A., Kühl, Michael & Burmølle, Mette, 2018, In: Applied and Environmental Microbiology. 84, 21, e01450.

Research output: Contribution to journal › Journal article › Research › peer-review

In vitro community synergy between bacterial soil isolates can be facilitated by pH stabilisation of the environment.

Herschend, J., Koren, K., Røder, Henriette Lyng, Brejnrod, A. D., Kühl, Michael & Burmølle, Mette, 2018, In: Applied and Environmental Microbiology. 84, 21, p. 1-15 e01450-18.

Research output: Contribution to journal › Journal article › Research › peer-review

In vivo and ex vivo inflammatory markers of common metabolic phenotypes in humans

Mærkedahl, R. B., Frøkiær, Hanne, Stenbæk, M. G., Nielsen, C. B., Lind, M. V., Lundtoft, C., Bohr, M. B., Ibrügger, S., Metzdorff, S. B., drb459, drb459, Pedersen, Oluf Borbye & Lauritzen, Lotte, 2018, In: Metabolic Syndrome and Related Disorders. 16, 1, p. 29-39 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Lactobacillus reuteri reduces bone loss in older women with low bone mineral density: a randomized, placebo-controlled, double-blind, clinical trial

Nilsson, A. G., Sundh, D., Backhed, F. & Lorentzon, M., 2018, In: Journal of Internal Medicine. 284, 3, p. 307-317

Research output: Contribution to journal › Journal article › Research › peer-review

A Common Allele in FGF21 Associated with Sugar Intake Is Associated with Body Shape, Lower Total Body-Fat Percentage, and Higher Blood Pressure

Frayling, T. M., Beaumont, R. N., Jones, S. E., Yaghootkar, H., Tuke, M. A., Ruth, K. S., Casanova, F., West, B., Locke, J., Sharp, S., Ji, Y., Thompson, W., Harrison, J., Etheridge, A. S., Gallins, P. J., Jima, D., Wright, F., Zhou, Y., Innocenti, F., Lindgren, C. M. & 6 others, Grarup, N., Murray, A., Freathy, R. M., Weedon, M. N., Tyrrell, J. & Wood, A. R., 2018, In: Cell Reports. 23, 2, p. 327-336

Research output: Contribution to journal › Journal article › Research › peer-review

A Diurnal Rhythm in Brown Adipose Tissue Causes Rapid Clearance and Combustion of Plasma Lipids at Wakening

van den Berg, R., Kooijman, S., Noordam, R., Ramkisoensing, A., Abreu-Vieira, G., Tambyrajah, L. L., Dijk, W., Ruppert, P., Mol, I. M., Kramar, B., Caputo, R., Puig, L. S., de Ruiter, E. M., Kroon, J., Hoekstra, M., van der Sluis, R. J., Meijer, O. C., Willems van Dijk, K., van Kerkhof, L. W. M., Christodoulides, C. & 8 others, Karpe, F., Gerhart-Hines, Zach, Kersten, S., Meijer, J. H., Coomans, C. P., van Heemst, D., Biermasz, N. R. & Rensen, P. C. N., 2018, In: Cell Reports. 22, 13, p. 3521-3533 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure

Sung, Y. J., Winkler, T. W., de Las Fuentes, L., Bentley, A. R., Brown, M. R., Kraja, A. T., Schwander, K., Ntalla, I., Guo, X., Franceschini, N., Lu, Y., Cheng, C-Y., Sim, X., Vojinovic, D., Marten, J., Musani, S. K., Li, C., Feitosa, M. F., Kilpeläinen, T. O., Richard, M. A. & 30 others, Noordam, R., Aslibekyan, S., Aschard, H., Bartz, T. M., Dorajoo, R., Liu, Y., Manning, A. K., Rankinen, T., Smith, A. V., Tajuddin, S. M., Tayo, B. O., Warren, H. R., Zhao, W., Zhou, Y., Matoba, N., Sofer, T., Alver, M., Amini, M., Boissel, M., Chai, J. F., Chen, X., Divers, J., Gandin, I., Gao, C., Giulianini, F., Goel, A., Harris, S. E., Hartwig, F. P., Christensen, K. & Loos, Ruth, 2018, In: American Journal of Human Genetics. 102, 3, p. 375-400 26 p.

Research output: Contribution to journal › Journal article › Research › peer-review

A Prospective Cohort Study in Patients with Type 2 Diabetes Mellitus for Validation of Biomarkers (PROVALID) - Study Design and Baseline Characteristics

Eder, S., Leierer, J., Kerschbaum, J., Rosivall, L., Wiecek, A., de Zeeuw, D., Mark, P. B., Heinze, G., Rossing, Peter, Heerspink, H. L. & Mayer, G., 2018, In: Kidney and Blood Pressure Research. 43, 1, p. 181-190

Research output: Contribution to journal › Journal article › Research › peer-review