- 2022
- Published
A saturated map of common genetic variants associated with human height
Yengo, L., Vedantam, S., Marouli, E., Sidorenko, J., Bartell, E., Sakaue, S., Graff, M., Eliasen, A. U., Jiang, Y., Raghavan, S., Miao, J., Arias, J. D., Graham, S. E., Mukamel, R. E., Spracklen, C. N., Yin, X., Chen, S-H., Ferreira, T., Highland, H. H., Ji, Y. & 37 others, , 2022, In: Nature. 610, p. 704–712Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A semaphorin-plexin-Rasal1 signaling pathway inhibits gastrin expression and protects against peptic ulcers
Xu, R., Höß, C., Swiercz, J. M., Brandt, D. T., Lutz, V., Petersen, N., Li, R., Zhao, D., Oleksy, A., Creigh-Pulatmen, T., Trokter, M., Fedorova, M., Atzberger, A., Strandby, R. B., Olsen, A. A., Achiam, M. P., Matthews, D., Huber, M., Gröne, H-J., Offermanns, S. & 1 others, , 2022, In: Science Translational Medicine. 14, 654, eabf1922.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A single-cell atlas of human and mouse white adipose tissue
Emont, M. P., Jacobs, C., Essene, A. L., Pant, D., Tenen, D., Colleluori, G., Di Vincenzo, A., Jørgensen, A. M., Dashti, H., Stefek, A., McGonagle, E., Strobel, S., Laber, S., Agrawal, S., Westcott, G. P., Kar, A., Veregge, M. L., Gulko, A., Srinivasan, H., Kramer, Z. & 18 others, , 2022, In: Nature. 603, p. 926-933Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A systems biology approach to study non-alcoholic fatty liver (NAFL) in women with obesity
Meijnikman, A. S., Lappa, D., Herrema, H., Aydin, O., Krautkramer, K. A., Tremaroli, V., Olofsson, L. E., Lundqvist, A., Bruin, S., Acherman, Y., Verheij, J., Hjorth, Siv Annegrethe, Gerdes, V. E. A., Schwartz, Thue W., Groen, A. K., Bäckhed, F., Nielsen, J. & Nieuwdorp, M., 2022, In: iScience. 25, 8, 18 p., 104828.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ADRA1A–Gαq signalling potentiates adipocyte thermogenesis through CKB and TNAP
Rahbani, J. F., Scholtes, C., Lagarde, D. M., Hussain, M. F., Roesler, A., Dykstra, C. B., Bunk, J., Samborska, B., O’Brien, S. L., Tripp, E., Pacis, A., Angueira, A. R., Johansen, O. S., Cinkornpumin, J., Hossain, I., Lynes, M. D., Zhang, Y., White, A. P., Pastor, W. A., Chondronikola, M. & 12 others, , 2022, In: Nature Metabolism. 4, 11, p. 1459-1473Research output: Contribution to journal › Letter › Research › peer-review
- Published
Actions of glucagon-like peptide-1 receptor ligands in the gut
Holst, Jens Juul, Andersen, Daniel Bjørklund & Grunddal, Kaare Villum, 2022, In: British Journal of Pharmacology. 179, 4, p. 727-742Research output: Contribution to journal › Review › Research › peer-review
- Published
Activation of succinate receptor 1 boosts human mast cell reactivity and allergic bronchoconstriction
Tang, X., Rönnberg, E., Säfholm, J., Thulasingam, M., Trauelsen, Mette, Schwartz, Thue W., Wheelock, C. E., Dahlén, S. E., Nilsson, G. & Haeggström, J. Z., 2022, In: Allergy: European Journal of Allergy and Clinical Immunology. 77, 9, p. 2677-2687Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acute and long-term effects of psilocybin on energy balance and feeding behavior in mice
Fadahunsi, N., Lund, Jens, Breum, Alberte Wollesen, Mathiesen, C. V., Larsen, I. B., Knudsen, Gitte Moos, Klein, A. B. & Clemmensen, Christoffer, 2022, In: Translational Psychiatry. 12, 12 p., 330.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acute changes in plasma glucose increases left ventricular systolic function in insulin-treated patients with type 2 diabetes and controls
Andersen, A., Jørgensen, P. G., Bagger, J., Baldassarre, M. P. A., Christensen, Mikkel Bring, Pedersen-Bjergaard, Ulrik, Lindhardt, T. B., Gislason, Gunnar Hilmar, Knop, Filip Krag & Vilsbøll, Tina, 2022, In: Diabetes, Obesity and Metabolism. 24, 6, p. 1123-1131Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acute concomitant GIP receptor antagonism during GLP-1 receptor agonism does not affect appetite, resting energy expenditure or food intake in patients with type 2 diabetes and overweight/obesity
Stensen, S., Krogh, L. L., wbf943, wbf943, Dela, Flemming, Hartmann, Bolette, Vilsbøll, Tina, Holst, Jens Juul, Rosenkilde, Mette, Christensen, Mikkel Bring, Gasbjerg, Lærke Smidt & Knop, Filip Krag, 2022, In: Diabetes, Obesity and Metabolism. 24, 9, p. 1882-1887Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acute effects of linagliptin on intact and total glucagon-like peptide-1 and gastric inhibitory polypeptide levels in insulin-dependent type 2 diabetes patients with and without moderate renal impairment
Meier, J. J., Quast, D. R., Nauck, M. A., Schenker, N., Deacon, Carolyn F., Holst, Jens Juul, Plum-Mörschel, L. & Kapitza, C., 2022, In: Diabetes, Obesity and Metabolism. 24, 5, p. 806-815Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acute effects on glucose tolerance by neprilysin inhibition in patients with type 2 diabetes
Albrechtsen, Nicolai Jacob Wewer, Møller, A., Martinussen, C., Gluud, Lise Lotte, Rashu, E. B., Richter, Michael Martin, Plomgaard, Peter Stendahl, Goetze, Jens P. , Kjeldsen, Sasha Alexandra Sampson, Hansen, L. H., Gustafsson, Finn, Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten & Bojsen-Møller, K. N., 2022, In: Diabetes, Obesity and Metabolism. 24, 10, p. 2017-2026 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adipose Tissue, Bile Acids, and Gut Microbiome Species Associated With Gallstones After Bariatric Surgery
Guman, M. S. S., Hoozemans, J. B., Haal, S., de Jonge, P. A., Aydin, Lappa, D., Meijnikman, A. S., Westerink, F., Acherman, Y., Bäckhed, F., de Brauw, M., Nielsen, J., Nieuwdorp, M., Groen, A. K. & Gerdes, V. E. A., 2022, In: Journal of Lipid Research. 63, 11, 9 p., 100280.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Amplicon sequencing demonstrates comparable follicular mycobiomes in patients with hidradenitis suppurativa compared with healthy controls
Ring, H. C., Thorsen, Jonathan Jan Ilve, Fuursted, K., Bjarnsholt, Thomas, Bay, Lene, Egeberg, Alexander, Ingham, Andreas, Vedel Nielsen, H., Frew, J. W., Saunte, Ditte Marie, Thomsen, Simon Francis & Jemec, Gregor, 2022, In: Journal of the European Academy of Dermatology and Venereology. 36, 7, p. e580-e583 4 p.Research output: Contribution to journal › Comment/debate › Research
- Published
An LDLR missense variant poses high risk of familial hypercholesterolemia in 30% of Greenlanders and offers potential of early cardiovascular disease intervention
Jørsboe, E., Andersen, M. K., Skotte, L., Stæger, F. F., Færgeman, N. J., Hanghøj, K., Santander, C. G., Senftleber, N. K., Diaz, L. J., Overvad, M., Waples, R. K., Geller, F., Bjerregaard, P., Melbye, M., Larsen, C. V. L., Feenstra, B., Anders Koch, K., Jørgensen, M. E., Grarup, N., Moltke, I. & 2 others, , 2022, In: Human Genetics and Genomics Advances. 3, 4, 10 p., 100118.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An adult-based genetic risk score for hepatic fat associates with liver and lipid traits in Danish children and adolescents
Huang, Yun, Stinson, Sara, Juel, H. B., Lund, Morten Asp Vonsild, Holm, L. A., Fonvig, Cilius Esmann, Grarup, Niels, Pedersen, Oluf Borbye, Christiansen, Michael, Krag, A., Stender, S., Holm, Jens-Christian & Hansen, Torben, 2022, In: Journal of Hepatology. 77, p. S450-S450 1 p., FRI104.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
An integrated model of obesity pathogenesis that revisits causal direction
Ludwig, D. S. & Sørensen, Thorkild I.A., 2022, In: Nature Reviews Endocrinology. 18, p. 261-262 2 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Ancestral diversity improves discovery and fine-mapping of genetic loci for anthropometric traits—The Hispanic/Latino Anthropometry Consortium
Fernández-Rhodes, L., Graff, M., Buchanan, V. L., Justice, A. E., Highland, H. M., Guo, X., Zhu, W., Chen, H. H., Young, K. L., Adhikari, K., Palmer, N. D., Below, J. E., Bradfield, J., Pereira, A. C., Glover, L. S., Kim, D., Lilly, A. G., Shrestha, P., Thomas, A. G., Zhang, X. & 96 others, , 2022, In: Human Genetics and Genomics Advances. 3, 2, 21 p., 100099.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Arginine-induced glucagon secretion and glucagon-induced enhancement of amino acid catabolism are not influenced by ambient glucose levels in mice
Maruszczak, K., Rasmussen, C., Ceutz, F. R., Ørgaard, A., Elmelund, E., Richter, Michael Martin, Holst, Jens Juul, Winther-Sørensen, Marie & Albrechtsen, Nicolai Jacob Wewer, 2022, In: American Journal of Physiology - Endocrinology and Metabolism. 323, p. E207–E214Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of apolipoprotein M and sphingosine-1-phosphate with brown adipose tissue after cold exposure in humans
Borup, A., Donkin, I., Boon, M. R., Frydland, M., Martinez-Tellez, B., Loft, A., Keller, S. H., Kjær, Andreas, Kjærgaard, Jesper, Hassager, Christian, Barrès, Romain, Rensen, P. C. N. & Christoffersen, Christina, 2022, In: Scientific Reports. 12, 1, 11 p., 18753.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of general health and lifestyle factors with the salivary microbiota – Lessons learned from the ADDITION-PRO cohort
Poulsen, C. S., Nygaard, Nikoline, Constancias, F., Stankevic, Evelina, Kern, T., Witte, D. R., Vistisen, D., Grarup, Niels, Pedersen, Oluf Borbye, Midjord-Belstrøm, Daniel & Hansen, Torben, 2022, In: Frontiers in Cellular and Infection Microbiology. 12, 15 p., 1055117.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of milk intake with hay fever, asthma, and lung function: a Mendelian randomization analysis
Skaaby, T., Kilpeläinen, Tuomas O., Mahendran, Y., Huang, L. O., Sallis, H., Thuesen, B. H., Kårhus, L. L., Leth-Møller, K. B., Grarup, Niels, Hansen, Torben, Pedersen, Oluf Borbye, Burgess, S., Munafò, M. R. & Linneberg, Allan René, 2022, In: European Journal of Epidemiology. 37, p. 713-722Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Asthma and Wheeze Severity and the Oropharyngeal Microbiota in Children and Adolescents
Thorsen, J., Stokholm, J., Rasmussen, M. A., Roggenbuck-Wedemeyer, M., Vissing, N. H., Mortensen, M. S., Brejnrod, A. D., Fleming, L., Bush, A., Roberts, G., Singer, F., Frey, U., Hedlin, G., Nordlund, B., Murray, C. S., Abdel-Aziz, M. I., Hashimoto, S., van Aalderen, W., Maitland-van der Zee, A. H., Shaw, D. & 13 others, , 2022, In: Annals of the American Thoracic Society. 19, 12, p. 2031-2043 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Atlas of exercise metabolism reveals time-dependent signatures of metabolic homeostasis
Sato, S., Dyar, K. A., Treebak, J. T., Jepsen, S. L., Ehrlich, A. M., Ashcroft, S. P., Trost, K., Kunzke, T., Prade, V. M., Small, L., Basse, A. L., Schönke, M., Chen, S., Samad, M., Baldi, P., Barrès, R., Walch, A., Moritz, T., Holst, J. J., Lutter, D. & 2 others, , 2022, In: Cell Metabolism. 34, 2, p. 329-345.e8 26 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Beta-Hydroxybutyrate Suppresses Hepatic Production of the Ghrelin Receptor Antagonist LEAP2
Holm, Stephanie Kjærulff, Husted, Anna Sofie, Skov, Louise Julie, Morville, T. H., Hagemann, C. A., Jorsal, T., Dall, M., Jakobsen, A., Klein, A. B., Treebak, Jonas Thue, Knop, Filip Krag, Schwartz, Thue W., Clemmensen, Christoffer & Holst, Birgitte, 2022, In: Endocrinology. 163, 6, 13 p., bqac038.Research output: Contribution to journal › Journal article › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity
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Determinants of plasma levels of proglucagon and the metabolic impact of glucagon receptor signalling: a UK Biobank study
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Targeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment
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mTORC1 controls murine postprandial hepatic glycogen synthesis via Ppp1r3b
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