- 2018
- Published
Genetic aspects of non-alcoholic fatty liver disease (NAFLD)
Stender, S., Grarup, N. & Hansen, Torben, 2018, The Human Gut-Liver-Axis in Health and Disease. Springer, p. 195-206 12 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Genetic determinants of glycated hemoglobin levels in the Greenlandic Inuit population
Appel, V. R., Moltke, Ida, Jørgensen, M. E., Bjerregaard, P., Linneberg, Allan René, Pedersen, Oluf Borbye, Albrechtsen, Anders, Hansen, Torben & Grarup, N., 2018, In: European Journal of Human Genetics. 26, 6, p. 868-875 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic insights into fetal growth and measures of glycaemic regulation and adiposity in adulthood: a family-based study
Hollensted, M., Ekstrøm, Claus Thorn, Pedersen, Oluf Borbye, Eiberg, Hans Rudolf Lytchoff, Hansen, Torben & Gjesing, A. P., 2018, In: BMC Medical Genetics. 19, p. 1-9 9 p., 207.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic predisposition to adiposity is associated with increased objectively assessed sedentary time in young children
Schnurr, T. M., Viitasalo, A., Eloranta, A., Damsgaard, Camilla Trab, Mahendran, Y., Have, C. T., Väistö, J., Hjorth, Mads Fiil, Christensen, L. B., Brage, S., Atalay, M., Lyytikäinen, L., Lindi, V., Lakka, T., Michaelsen, Kim F., Kilpeläinen, Tuomas O. & Hansen, Torben, 2018, In: International Journal of Obesity. 42, 1, p. 111-114 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic risk score of insulin resistance risk variants is associated with increased risk of coronary artery disease in patients referred to coronary angiography
Skals, R. K., Krogager, M. L., Appel, E. V. R., Schnurr, T. M., Have, C. T., Gislason, Gunnar Hilmar, Poulsen, Henrik Enghusen, Køber, Lars Valeur, Engstrøm, Thomas, Stender, S., Hansen, Torben, Grarup, N., Andersson, C., Torp-Pedersen, C. & Weeke, P. E., 2018, In: European Heart Journal. 39, p. 752-753Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic risk scores for body fat distribution attenuate weight loss in women during dietary intervention
Svendstrup, M., Allin, K. H., Sørensen, Thorkild I.A., Hansen, T. H., Grarup, N., Hansen, Torben & drb459, drb459, 2018, In: International Journal of Obesity. 42, 3, p. 370-375 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetics of metabolic traits in Greenlanders: lessons from an isolated population
Lepola, Mette Andersen & Hansen, Torben, 2018, In: Journal of Internal Medicine. 284, 5, p. 464-477 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-Wide Interactions with Dairy Intake for Body Mass Index in Adults of European Descent
Smith, C. E., Follis, J. L., Dashti, H. S., Tanaka, T., Graff, M., Fretts, A. M., Kilpeläinen, T. O., Wojczynski, M. K., Richardson, K., Nalls, M. A., Schulz, C-A., Liu, Y., Frazier-Wood, A. C., van Eekelen, E., Wang, C., de Vries, P. S., Mikkilä, V., Rohde, R., Psaty, B. M., Hansen, T. & 43 others, , 2018, In: Molecular Nutrition & Food Research. 62, 3, p. 1-12 12 p., 1700347.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation
Teumer, A., Chaker, L., Groeneweg, S., Li, Y., Di Munno, C., Barbieri, C., Ahluwalia, Tarun Veer Singh, Astrup, A., Linneberg, Allan René, Pedersen, Oluf Borbye, Sørensen, Thorkild I.A. & ThyroidOmics Consortium, T. C., 2018, In: Nature Communications. 9, 14 p., 4455.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association analyses identify 39 new susceptibility loci for diverticular disease
Maguire, L. H., Handelman, S. K., Du, X., Chen, Y., Pers, Tune H & Speliotes, E. K., 2018, In: Nature Genetics. 50, 10, p. 1359-1365Research output: Contribution to journal › Letter › Research › peer-review
- Published
Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis
Waage, J., Standl, M., Curtin, J. A., Jessen, L. E., Thorsen, J., Tian, C., Schoettler, N., 23andMe Research Team, AAGC collaborators, Flores, C., Abdellaoui, A., Ahluwalia, T. S., Alves, A. C., Amaral, A. F. S., Antó, J. M., Arnold, A., Barreto-Luis, A., Baurecht, H., van Beijsterveldt, C. E. M., Bleecker, E. R. & 33 others, , 2018, In: Nature Genetics. 50, 8, p. 1072-1080Research output: Contribution to journal › Letter › Research › peer-review
- Published
Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics
Beaumont, R. N., Warrington, N. M., Cavadino, A., Tyrrell, J., Nodzenski, M., Horikoshi, M., Geller, F., Myhre, R., Richmond, R. C., Paternoster, L., Bradfield, J. P., Kreiner-Moller, E., Huikari, V., Metrustry, S., Lunetta, K. L., Painter, J. N., Hottenga, J-J., Allard, C., Barton, S. J., Espinosa, A. & 66 others, , 2018, In: Human Molecular Genetics. 27, 4, p. 742-756 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glimepiride monotherapy versus combination of glimepiride and linagliptin therapy in patients with HNF1A-diabetes: a protocol for a randomised, double-blinded, placebo-controlled trial
Christensen, A. S., Storgaard, H., Hædersdal, S., Hansen, Torben, Knop, Filip Krag & Vilsbøll, Tina, 2018, In: BMJ Open. 8, p. 1-9 e022517.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon receptor signaling in metabolic diseases
Albrechtsen, Nicolai Jacob Wewer, 2018, In: Peptides. 100, p. 42-47Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-Like Peptide-1 Inhibits Prandial Gastrointestinal Motility Through Myenteric Neuronal Mechanisms in Humans
Halim, M. A., Degerblad, M., Sundbom, M., Karlbom, U., Holst, Jens Juul, Webb, D. & Hellstrom, P. M., 2018, In: Journal of Clinical Endocrinology & Metabolism. 103, 2, p. 575-585Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide 1 in health and disease
Andersen, A., Lund, A., Knop, Filip Krag & Vilsbøll, Tina, 2018, In: Nature Reviews Endocrinology. 14, p. 390-403Research output: Contribution to journal › Review › Research › peer-review
- Published
Glucagon-like peptide-1 receptor agonists and cardiovascular disease: from LEADER to EXSCEL
Torekov, Signe Sørensen, 2018, In: Cardiovascular Research. 114, 10, p. e70-e71 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Glucose Tolerance Tests and Osteocalcin Responses in Healthy People
Starup-Linde, J., Westberg-Rasmussen, S., Lykkeboe, S., Handberg, A., Hartmann, Bolette, Holst, Jens Juul, Hermansen, K., Vestergaard, P. & Gregersen, S., 2018, In: Frontiers in Endocrinology. 9Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Godkendelse af personlig medicin
Sørensen, Thorkild I.A., 2018, In: Ugeskrift for Laeger. 180, p. 1054 1 p., V69798 .Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gut: a key player in the pathogenesis of type 2 diabetes?
Muscogiuri, G., Balercia, G., Barrea, L., Cignarelli, A., Giorgino, F., Holst, Jens Juul, Laudisio, D., Orio, F., Tirabassi, G. & Colao, A., 2018, In: Critical Reviews in Food Science and Nutrition. 58, 8, p. 1294–1309Research output: Contribution to journal › Review › Research › peer-review
- Published
Gut microbiota dysbiosis is associated with malnutrition and reduced plasma amino acid levels: Lessons from genome-scale metabolic modeling
Kumar, M., Ji, B., Babaei, P., Das, P., Lappa, D., Ramakrishnan, G., Fox, T. E., Haque, R., Petri, W. A., Backhed, F. & Nielsen, J., 2018, In: Metabolic Engineering. 49, p. 128-142Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gut microbiota regulates maturation of the adult enteric nervous system via enteric serotonin networks
De Vedder, F., Grasset, E., Holm, L. M., Karsenty, G., Macpherson, A. J., Olofsson, L. E. & Backhed, F., 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 25, p. 6458-6463Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hemodynamic Effects of Glucagon: A Literature Review
Petersen, K. M., Bogevig, S., Holst, Jens Juul, Knop, Filip Krag & Christensen, Mikkel Bring, 2018, In: Journal of Clinical Endocrinology & Metabolism. 103, 5, p. 1804-1812Research output: Contribution to journal › Review › Research › peer-review
- Published
Hepatic NAD+ levels and NAMPT abundance are unaffected during prolonged high-fat diet consumption in C57BL/6JBomTac mice
Dall, M., Penke, M., Sulek, K., Matz-Soja, M., Holst, Birgitte, Garten, A., Kiess, W. & Treebak, Jonas Thue, 2018, In: Molecular and Cellular Endocrinology. 473, p. 245-256 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hepatitis B virus upregulates host microRNAs that target apoptosis-regulatory genes in an in vitro cell model
Nielsen, K. O., Jacobsen, K. S., Mirza, A. H., Winther, T. N., Størling, J., Glebe, D., Pociot, Flemming & Høgh, Birthe, 2018, In: Experimental Cell Research. 371, 1, p. 92-103Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High Blood Eosinophils in Acute Exacerbation of Chronic Obstructive Lung Disease Is Not Associated with Higher Risk of Readmission or Mortality
Jabarkhil, A., Janner, Julie Hjortsø, Moberg, M., Eriksen, N., Pedersen, M. N., Jensen, C. B., Ängquist, Lars, Vestbo, J., Jess, T. & Porsbjerg, Celeste Michala, 2018, In: American Journal of Respiratory and Critical Care Medicine. 197, 1 p., A3123.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Higher chlorzoxazone clearance in obese children compared with nonobese peers
Gade, C., Dalhoff, Kim, Petersen, Tonny Studsgaard, Riis, T., Schmeltz, C., Chabanova, E., Christensen, H. R., Mikus, G., Burhenne, J., Holm, Jens-Christian & Holst, H., 2018, In: British Journal of Clinical Pharmacology. 84, 8, p. 1738-1747 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human P2Y11 expression level affects human P2X7 receptor-mediated cell death
Dreisig, K., Sund, L., Dommer, M. W., Kristensen, N. P., Boddum, K., Viste, R., Fredholm, S., Ødum, Niels, Jäättelä, M., Skov, Søren & Kornum, Birgitte Rahbek, 2018, In: Frontiers in Immunology. 9, JUN, 12 p., 1159.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hyperglucagonemia correlates with plasma levels of non-branched-chain amino acids in patients with liver disease independent of type 2 diabetes
Albrechtsen, Nicolai Jacob Wewer, Junker, A. E., Christensen, M., Hædersdal, S., Wibrand, F., Lund, A. M., Galsgaard, Katrine Douglas, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2018, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 314, 1, p. G91-G96Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hyperosmolar Duodenal Saline Infusion Lowers Circulating Ghrelin and Stimulates Intestinal Hormone Release in Young Men
Veedfald, Simon, Wu, T., Bound, M., Grivell, J., Hartmann, Bolette, Rehfeld, Jens Frederik, Deacon, Carolyn F., Horowitz, M., Holst, Jens Juul & Rayner, C. K., 2018, In: Journal of Clinical Endocrinology & Metabolism. 103, 12, p. 4409-4418Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypertension genetic risk score is associated with burden of coronary heart disease among patients referred for coronary angiography
Krogager, M. L., Skals, R. K., Appel, E. V. R., Schnurr, T. M., pjx571, pjx571, Have, C. T., Pedersen, Oluf Borbye, Engstrøm, Thomas, Roden, D. M., Gislason, Gunnar Hilmar, Poulsen, Henrik Enghusen, Køber, Lars Valeur, Stender, Steen, Hansen, Torben, Grarup, N., Andersson, C., Torp-Pedersen, Christian & Weeke, P. E., 2018, In: P L o S One. 13, 12, p. 1-17 e0208645.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of novel LEPR mutations in Pakistani families with morbid childhood obesity
Niazi, R. K., Gjesing, A. P., Hollensted, M., Have, C. T., Grarup, N., Pedersen, Oluf Borbye, Ullah, A., Shahid, G., Ahmad, W., Gul, A. & Hansen, Torben, 2018, In: BMC Medical Genetics. 19, 1, p. 1-8 199.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of protein phosphatase involvement in the AT2 receptor-induced activation of endothelial nitric oxide synthase
Peluso, A., 2018, In: Clinical Science.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of Gut Microbiota and Diet on the Development of Atherosclerosis in Apoe-/- Mice
Jonsson, A. L., Caesar, R., Akrami, R., Reinhardt, C., Hallenius, F. F., Boren, J. & Baeckhed, F., 2018, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 38, 10, p. 2318-2326 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of a vegan diet on the human salivary microbiota
Hansen, T. H., Kern, T., Bak, Emilie Glad, Kashani, A., Allin, K. H., Nielsen, T., Hansen, Torben & Pedersen, Oluf Borbye, 2018, In: Scientific Reports. 8, p. 1-11 5847.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vitro co-cultures of human gut bacterial species as predicted from co-occurrence network analysis
Das, P., Ji, B., Kovatcheva-Datchary, P., Bäckhed, F. & Nielsen, J., 2018, In: PLOS ONE. 13, 3, p. 1-14 e0195161.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increase in clinically recorded type 2 diabetes after colectomy
Jensen, A. B., Sørensen, Thorkild I.A., Pedersen, Oluf Borbye, Jess, T., Brunak, Søren & Allin, K. H., 2018, In: eLife. 7, e37420.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incretin responses to oral glucose and mixed meal tests and changes in fasting glucose levels during 7 years of follow-up: The Hoorn Meal Study
Koopman, A. D. M., Rutters, F., Rauh, S. P., Nijpels, G., Holst, Jens Juul, Beulens, J. W., Alssema, M. & Dekker, J. M., 2018, In: PloS one. 13, 1, 13 p., e0191114.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Indicator of RNA oxidation in urine for the prediction of mortality in patients with type 2 diabetes and microalbuminuria: a post-hoc analysis of the Steno-2 trial
Kjær, L. K., Oellgaard, J., Henriksen, T., Gaede, P., Pedersen, Oluf Borbye & Poulsen, Henrik Enghusen, 2018, In: Free Radical Biology and Medicine. 129, p. 247-255Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Individual and combined glucose-lowering effects of glucagon receptor antagonism and dipeptidyl peptidase-4 inhibition
Maagensen, H., Haedersdal, S., Lund, A., Nielsen-Hannerup, E., Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2018, In: Diabetologia. 61, p. S246-S247Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Inhibiting RHOA Signaling in Mice Increases Glucose Tolerance and Numbers of Enteroendocrine and Other Secretory Cells in the Intestine
Petersen, N., Frimurer, Thomas Michael, Pedersen, M. T., Egerod, Kristoffer Lihme, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Grapin-Botton, A., Jensen, Kim Bak & Schwartz, Thue W., 2018, In: Gastroenterology. 155, 4, p. 1164-1176 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulin Secretion Depends on Intra-islet Glucagon Signaling
Svendsen, B., Larsen, Olav, Gabe, M. B. N., Christiansen, Charlotte Bayer, Rosenkilde, M. M., Drucker, D. J. & Holst, Jens Juul, 2018, In: Cell Reports. 25, 5, p. 1127-1134.E2Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interethnic analyses of blood pressure loci in populations of East Asian and European descent
The International Genomics of Blood Pressure (iGEN-BP) Consortium, T. I. G. O. B. P. (. C., 2018, In: Nature Communications. 9, 5052.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interleukin-6 Delays Gastric Emptying in Humans with Direct Effects on Glycemic Control
Lehrskov, L. L., Lyngbaek, M. P., Soederlund, L., Legaard, G. E., Ehses, J. A., Heywood, S. E., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Karstoft, K., Pedersen, Bente Klarlund & Ellingsgaard, H., 2018, In: Cell Metabolism. 27, 6, p. 1201-1211Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Is abdominal obesity at baseline influencing weight changes in observational studies and during weight loss interventions?
Svendstrup, M., Allin, K. H., Ängquist, Lars, Schnohr, P., Jensen, G. B., Linneberg, Allan René, Thuesen, B., Astrup, A., Saris, W. H. M., drb459, drb459 & Sørensen, Thorkild I.A., 2018, In: American Journal of Clinical Nutrition. 108, 5, p. 913-921 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
L cell secretory responses after gastric bypass surgery can be imitated in un-operated individuals by modulating carbohydrate digestion
Martinussen, C., Bojsen-Moller, K. N., Dirksen, C., Svane, M. S., Holst, Jens Juul & Madsbad, Sten, 2018, In: Diabetologia. 61, S1, p. S124-S125 244.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Ligand-selective small molecule modulators of the constitutively active vGPCR US28
Amarandi, R., Lückmann, Michael, Melynis, M., Jakobsen, M. H., Fallah, Z., Spiess, Katja, Hjortø, Gertrud Malene, Pui, A., Frimurer, Thomas Michael & Rosenkilde, Mette, 2018, In: European Journal of Medicinal Chemistry. 155, p. 244-254Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Loss-of-function variants in ADCY3 increase risk of obesity and type 2 diabetes
Grarup, N., Moltke, Ida, Lepola, Mette Andersen, Dalby, M., Vitting-Seerup, K., Kern, T. S., Mahendran, Y., Jørsboe, E., Larsen, C. V. L., Dahl-Petersen, I. K., Gilly, A., Suveges, D., Dedoussis, G., Zeggini, E., Pedersen, Oluf Borbye, Andersson, Robin, Bjerregaard, P., Jørgensen, M. E., Albrechtsen, Anders & Hansen, Torben, 2018, In: Nature Genetics. 50, 2, p. 172-174 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Maternal and fetal genetic contribution to gestational weight gain
Warrington, N. M., Richmond, R., Fenstra, B., Myhre, R., Gaillard, R., Paternoster, L., Wang, C. A., Beaumont, R. N., Das, S., Murcia, M., Barton, S. J., Espinosa, A., Thiering, E., Atalay, M., Pitkänen, N., Ntalla, I., Jonsson, A. E., Freathy, R., Karhunen, V., Tiesler, C. M. T. & 44 others, , 2018, In: International journal of obesity (2005). 42, p. 775–784Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Maternal obesity reprograms offspring's executive brain centers in a sex-specific manner? An Editorial for "Perinatal high fat diet and early life methyl donor supplementation alter one carbon metabolism and DNA methylation in the brain" on page 362
Plucinska, Kaja & Barger, S. W., 2018, In: Journal of Neurochemistry. 145, 5, p. 358-361Research output: Contribution to journal › Editorial › Research
- Published
Maternal smoking during pregnancy and offspring overweight: is there a dose-response relationship? An individual patient data meta-analysis
Albers, L., Sobotzki, C., Kuß, O., Ajslev, T., Batista, R. F., Bettiol, H., Brabin, B., Buka, S. L., Cardoso, V. C., Clifton, V. L., Devereux, G., Gilman, S. E., Grzeskowiak, L. E., Heinrich, J., Hummel, S., Jacobsen, G. W., Jones, G., Koshy, G., Morgen, C. S., Oken, E. & 10 others, , 2018, In: International Journal of Obesity. 42, p. 1249-1264 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Maturation of the gut microbiome and risk of asthma in childhood
Stokholm, Jakob, Blaser, M. J., Thorsen, Jonathan Jan Ilve, Rasmussen, Morten Arendt, Waage, J. E., Vinding, R. K., Schoos, A. M., Kunøe, A., Fink, N. R., Chawes, Bo Lund Krogsgaard, Bønnelykke, Klaus, Brejnrod, A. D., Mortensen, M. S., Abu Al-Soud, W., Sørensen, Søren Johannes & Bisgaard, H., 2018, In: Nature Communications. 9, 10 p., 141.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Meta-analysis of exome array data identifies six novel genetic loci for lung function
Jackson, V. E., Latourelle, J. C., Wain, L. V., Smith, A. V., Grove, M. L., Bartz, T. M., Obeidat, M., Province, M. A., Gao, W., Qaiser, B., Porteous, D. J., Cassano, P. A., Ahluwalia, T. S., Grarup, N., Li, J., Altmaier, E., Marten, J., Harris, S. E., Manichaikul, A., Pottinger, T. D. & 31 others, , 2018, In: Wellcome Open Research. 3, p. 1-28Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabolic and hepatic effects of liraglutide, obeticholic acid and elafibranor in diet-induced obese mouse models of biopsy-confirmed nonalcoholic steatohepatitis
Tølbøl, K. S., Kristiansen, M. N. B., Hansen, H. H., Veidal, S. S., Rigbolt, K. T. G., Gillum, M. P., Jelsing, J., Vrang, N. & Feigh, M., 2018, In: World Journal of Gastroenterology. 24, 2, p. 179-194 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabolite ratios as potential biomarkers for type 2 diabetes: a DIRECT study
Molnos, S., Wahl, S., Haid, M., Eekhoff, E. M. W., Pool, R., Floegel, A., Deelen, J., Much, D., Prehn, C., Breier, M., Draisma, H. H., van Leeuwen, N., Simonis-Bik, A. M. C., Jonsson, A., Willemsen, G., Bernigau, W., Wang-Sattler, R., Suhre, K., Peters, A., Thorand, B. & 24 others, , 2018, In: Diabetologia. 61, 1, p. 117-129 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabolomic profiling of maternal hair suggests rapid development of intrahepatic cholestasis of pregnancy
Seymour, J. V. D., Tu, S., He, X., Zhang, H., Han, T., Baker, P. N. & Sulek, K., 2018, In: Metabolomics. 14, 6, p. 1-5 79.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metformin er en mulig glukagonlignende peptid-1-stimulator
Bahne, E., Brønden, A., Vilsbøll, Tina & Knop, Filip Krag, 2018, In: Ugeskrift for Laeger. 180, 12, 4 p., V07170516.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metformin-induced glucagon-like peptide-1 secretion contributes to the actions of metformin in type 2 diabetes
Bahne, E., Sun, E. W. L., Young, R. L., Hansen, M., Sonne, D. P., Hansen, J. S., Rohde, U., Liou, A. P., Jackson, M. L., de Fontgalland, D., Rabbitt, P., Hollington, P., Sposato, L., Due, S., Wattchow, D. A., Rehfeld, Jens Frederik, Holst, Jens Juul, Keating, D. J., Vilsbøll, Tina & Knop, Filip Krag, 2018, In: JCI Insight. 3, 23, p. 1-16 e93936.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Methodology for Accurate Detection of Mitochondrial DNA Methylation
Mechta, Mie, Ingerslev, L. R. & Barrès, Romain, 2018, In: Journal of Visualized Experiments. 135, e57772.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Microbial regulation of the L cell transcriptome
Arora, Tulika, Akrami, R., Pais, R., Bergqvist, L., Johansson, B. R., Schwartz, Thue W., Reimann, F., Gribble, F. M. & Bäckhed, F., 2018, In: Scientific Reports. 8, p. 1-9 1207.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Microbially Produced Imidazole Propionate Impairs Insulin Signaling through mTORC1
Koh, A., Molinaro, A., Stahlman, M., Khan, M. T., Schmidt, C., Manneras-Holm, L., Wu, H., Carreras, A., Jeong, H., Olofsson, L. E., Bergh, P., Gerdes, V., Hartstra, A., de Brauw, M., Perkins, R., Nieuwdorp, M., Bergstrom, G. & Backhed, F., 2018, In: Cell. 175, 4, p. 947-961.e17Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular genetic overlap between migraine and major depressive disorder
Yang, Y., Zhao, H., Boomsma, D. I., Ligthart, L., Belin, A. C., Smith, G. D., Esko, T., Freilinger, T. M., Hansen, T. F., Ikram, M. A., Kallela, M., Kubisch, C., Paraskevi, C., Strachan, D. P., Wessman, M., Gormley, P., Anttila, V., Winsvold, B. S., Palta, P., Esko, T. & 30 others, , 2018, In: European Journal of Human Genetics. 26, 8, p. 1202-1216 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mono- and co-activation of the GIP and GLP-1 receptors inhibits bone resorption
Bergmann, N. C., Lund, A., Heimburger, S. M., Gasbjerg, Lærke Smidt, Jørgensen, Niklas Rye, Jessen, L., Hartmann, Bolette, Holst, Jens Juul, Christensen, Mikkel Bring, Vilsbøll, Tina & Knop, Filip Krag, 2018, In: Diabetologia. 61, S.1, p. S348-S348 717.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function
Wyss, A. B., Sofer, T., Lee, M. K., Terzikhan, N., Nguyen, J. N., Lahousse, L., Latourelle, J. C., Smith, A. V., Bartz, T. M., Feitosa, M. F., Gao, W., Ahluwalia, T. S., Tang, W., Oldmeadow, C., Duan, Q., de Jong, K., Wojczynski, M. K., Wang, X-Q., Noordam, R., Hartwig, F. P. & 82 others, , 2018, In: Nature Communications. 9, 15 p., 2976.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No changes in levels of bone formation and resorption markers following a broad-spectrum antibiotic course
Mikkelsen, K. H., Vilsbøll, Tina, Holst, Jens Juul, Hartmann, Bolette, Knop, Filip Krag & Frost, M., 2018, In: BMC Endocrine Disorders. 18, 6 p., 60.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Non-insulin pharmacological therapies for treating type 1 diabetes
Frandsen, C. S., Dejgaard, T. F., Madsbad, Sten & Holst, Jens Juul, 2018, In: Expert Opinion on Pharmacotherapy. 19, 9, p. 947-960Research output: Contribution to journal › Review › Research › peer-review
- Published
Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries
Feitosa, M. F., Kraja, A. T., Chasman, D. I., Sung, Y. J., Winkler, T. W., Ntalla, I., Guo, X., Franceschini, N., Cheng, C-Y., Sim, X., Vojinovic, D., Marten, J., Musani, S. K., Li, C., Bentley, A. R., Brown, M. R., Schwander, K., Richard, M. A., Noordam, R., Aschard, H. & 31 others, , 2018, In: PLoS ONE. 13, 6, p. 1-36 e0198166.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Older subjects with β-cell dysfunction have an accentuated incretin release
De Jesús Garduno-Garcia, J., Gastaldelli, A., DeFronzo, R. A., Lertwattanarak, R., Holst, Jens Juul & Musi, N., 2018, In: Journal of Clinical Endocrinology and Metabolism. 103, 7, p. 2613-2619 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
One-carbon metabolism markers are associated with cardiometabolic risk factors
Lind, M. V., Lauritzen, Lotte, drb459, drb459, Hansen, Torben, Pedersen, Oluf Borbye, Kristensen, M. B. & Ross, A. B., 2018, In: Nutrition, Metabolism & Cardiovascular Diseases. 28, 4, p. 402-410 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Outcome of childhood obesity
Pedersen, D. C., Sørensen, Thorkild I.A. & Baker, J. L., 2018, Eating Disorders and Obesity in Children and Adolescents. Hebebrand, J. & Herpertz-Dahlmann, B. (eds.). 1 ed. St. Louis, Missouri: Elsevier, p. 165-169 5 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Oxyntomodulin: actions and role in diabetes
Holst, Jens Juul, Albrechtsen, Nicolai Jacob Wewer, Gabe, M. B. N. & Rosenkilde, M. M., 2018, In: Peptides. 100, p. 48-53 6 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Parsing the Potential Neuroendocrine Actions of FGF21 in Primates
Gillum, M. P., 2018, In: Endocrinology. 159, 5, p. 1966-1970 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Patient profiling for success after weight loss surgery (GO Bypass study): An interdisciplinary study protocol
Christensen, Bodil Just, Schmidt, J. B., Nielsen, M. S., Tækker, L., Holm, Lotte, Lunn, Susanne, Bredie, Wender, Ritz, C., Holst, Jens Juul, Hansen, Torben, Hilbert, A., le Roux, C. W., Hulme, O. J., Siebner, Hartwig Roman, Morville, T., Naver, L., Floyd, A. K. & Sjödin, Anders Mikael, 2018, In: Contemporary Clinical Trials Communications. 10, p. 121-130 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Patients with Obesity Caused by Melanocortin-4 Receptor Mutations Can Be Treated with a Glucagon-like Peptide-1 Receptor Agonist
Iepsen, E. W., Zhang, J., Thomsen, Henrik S., Hansen, E. L., Hollensted, M., Madsbad, Sten, Hansen, Torben, Holst, Jens Juul, Holm, Jens-Christian & Torekov, Signe Sørensen, 2018, In: Cell Metabolism. 28, 1, p. 23-32.e3Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Perturbations in the p53/miR-34a/SIRT1 pathway in the R6/2 Huntington's disease model
Reynolds, R. H., Petersen, M. H., Willert, C. W., Heinrich, M., Nymann, N., Dall, M., Treebak, Jonas Thue, Björkqvist, M., Silahtaroglu, Asli, Hasholt, Lis Frydenreich & Nørremølle, Anne, 2018, In: Molecular and Cellular Neuroscience. 88, p. 118-129Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Perturbations of NAD+ salvage systems impact mitochondrial function and energy homeostasis in mouse myoblasts and intact skeletal muscle
Andersen, M. A., Dall, M., Jensen, Benjamin Anderschou Holbech, Prats Gavalda, Clara, Madsen, S., Basse, A. L., Graae, A., Risis, S., Goldenbaum, J., Quistorff, B., Larsen, Steen, Vienberg, S. G. & Treebak, Jonas Thue, 2018, In: American Journal of Physiology: Endocrinology and Metabolism. 314, 4, p. E377-E395 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma Proteome Profiling Reveals Dynamics of Inflammatory and Lipid Homeostasis Markers after Roux-En-Y Gastric Bypass Surgery
Albrechtsen, Nicolai Jacob Wewer, Geyer, P. E., Doll, S., Treit, P. V., Bojsen-Møller, K. N., Martinussen, C., Jørgensen, N. B., Torekov, Signe Sørensen, Meier, F., Niu, Lili, Santos, A., Keilhauer, E. C., Holst, Jens Juul, Madsbad, Sten & Mann, Matthias, 2018, In: Cell Systems. 7, 6, p. 601-612Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pleiotropic Effects of Heparins: From Clinical Applications to Molecular Mechanisms in Hepatocellular Carcinoma
Korhan, P., Yılmaz, Y., Bağırsakçı, E., Güneş, A., Topel, Hande, Carr, B. I. & Atabey, N., 2018, In: Canadian Journal of Gastroenterology. 2018, p. 7568742Research output: Contribution to journal › Review › Research › peer-review
- Published
Postprandial effects of individual and combined GIP and GLP-1 receptor antagonism in healthy subjects
Gasbjerg, Lærke Smidt, Helsted, M. M., wbf943, wbf943, Lanng, A. R., Stensen, S., Jakobsen, M. H., Hartmann, Bolette, Christensen, Mikkel Bring, Holst, Jens Juul, Vilsbøll, Tina, Rosenkilde, M. M. & Knop, Filip Krag, 2018, In: Diabetologia. 61, S1, p. S246-S246 503.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Pre-Meal Effect of Whey Proteins on Metabolic Parameters in Subjects with and without Type 2 Diabetes: A Randomized, Crossover Trial
Bjørnshave, A., Hermansen, K. & Holst, Jens Juul, 2018, In: Nutrients. 10, 2, p. 1-13 122.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preserved glucose response to low-dose glucagon after exercise in insulin pump-treated individuals with type 1 diabetes: a randomised crossover study
Steineck, I. I. K., Ranjan, A., Schmidt, S., Clausen, T. R., Holst, Jens Juul & Norgaard, K., 2018, In: Diabetologia. 61, S1, p. S75-S76 2 p., 146.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Profiling of G protein-coupled receptors in vagal afferents reveals novel gut-to-brain sensing mechanisms
Egerod, Kristoffer Lihme, Petersen, N., Timshel, P. N., Rekling, Jens Christian, Wang, Y., Liu, Q., Schwartz, Thue W. & Gautron, L., 2018, In: Molecular Metabolism. 12, p. 62-75 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prospective studies exploring the possible impact of an ID3 polymorphism on changes in obesity measures
Svendstrup, M., Appel, E. V. R., Sandholt, C. H., Ahluwalia, Tarun Veer Singh, Ängquist, Lars, Thuesen, B. H., Jørgensen, M. E., Pedersen, Oluf Borbye, Grarup, N., Hansen, Torben, Sørensen, Thorkild I.A. & drb459, drb459, 2018, In: Obesity. 26, 4, p. 747-754 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteomics Analysis of Skeletal Muscle from Leptin-Deficient ob/ob Mice Reveals Adaptive Remodeling of Metabolic Characteristics and Fiber Type Composition
Schönke, M., Björnholm, M., Chibalin, A. V., Zierath, Juleen R & Deshmukh, Atul Shahaji, 2018, In: Proteomics. 18, 5-6, p. 1-11 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protocol for Meal-time Administration of Exenatide for Glycaemic Control in Type 1 Diabetes Cases (The MAG1C trial): A randomised, double-blinded, placebo-controlled trial
Johansen, N. J., Dejgaard, T. F., Lund, A., Vilsbøll, Tina, Andersen, H. U. & Knop, Filip Krag, 2018, In: BMJ Open. 8, 6, 8 p., 021861.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantitative perfusion assessment of intestinal anastomoses in pigs treated with glucagon-like peptide 2
Nerup, N., Ring, L. L., Strandby, R. B., Egeland, C., Svendsen, M. B. S., Hasselby, Jane Preuss, Willemoe, G. L., Hartmann, Bolette, Svendsen, Lars Bo & Achiam, Michael Patrick, 2018, In: Langenbeck's Archives of Surgery. 403, 7, p. 881-889Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rectal insulin instillation inhibits inflammation and tumor development in chemically-induced colitis
Yassin, M., Sadowska, Z., Tritsaris, Katerina, Kissow, Hannelouise, Hansen, Camilla Hartmann Friis, Forman, Julie Lyng, Rogler, G., Troelsen, J. T., Pedersen, Anders Elm & Olsen, Jørgen, 2018, In: Journal of Crohn's and Colitis. 12, 12, p. 1459–1474 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduced obesity, diabetes, and steatosis upon cinnamon and grape pomace are associated with changes in gut microbiota and markers of gut barrier
Van Hul, M., Geurts, L., Plovier, H., Druart, C., Everard, A., Ståhlman, M., Rhimi, M., Chira, K., Teissedre, P., Delzenne, N. M., Maguin, E., Guilbot, A., Brochot, A., Gérard, P., Bäckhed, F. & Cani, P. D., 2018, In: American Journal of Physiology: Endocrinology and Metabolism. 314, 4, p. E334-E352 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduced risk of heart failure with intensified multifactorial intervention in individuals with type 2 diabetes and microalbuminuria: 21 years of follow-up in the randomised Steno-2 study
Oellgaard, J., Gaede, P., Rossing, Peter, Rorth, R., Køber, Lars Valeur, Parving, H. & Pedersen, Oluf Borbye, 2018, In: Diabetologia. 61, 8, p. 1724-1733Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Relationship between Optimum Mini‐doses of Glucagon and Insulin Levels when Treating Mild Hypoglycaemia in Patients with Type 1 Diabetes: A Simulation Study
Ranjan, A., Wendt, S. L., Schmidt, S., Madsbad, Sten, Holst, Jens Juul, Madsen, H., Knudsen, C. B., Jørgensen, J. B. & Nørgaard, Kirsten, 2018, In: Basic & Clinical Pharmacology & Toxicology. 122, 3, p. 322-330Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Renoprotective effects of dulaglutide in patients with T2DM and CKD
Sorensen, Charlotte Mehlin & Holst, Jens Juul, 2018, In: Nature Reviews. Nephrology. 14, 11, p. 659-660Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Response to Letter to the Editor: "Hemodynamic Effects of Glucagon: A Literature Review"
Petersen, K. M., Bøgevig, S., Holst, Jens Juul, Knop, Filip Krag & Christensen, Mikkel Bring, 2018, In: The Journal of clinical endocrinology and metabolism. 103, 12, p. 4480-4481 2 p.Research output: Contribution to journal › Comment/debate › Research
- Published
Restoration of enteroendocrine and pancreatic function after internal hernia and short bowel syndrome in a young woman with gastric bypass: a 2-year follow-up
Borghede, M., Vinter-Jensen, L., Rasmussen, H. H., Veedfald, Simon, Rehfeld, Jens Frederik, Hartmann, Bolette, Holst, Jens Juul, Knop, Filip Krag & Sonne, D. P., 2018, In: Physiological Reports. 6, 9, 6 p., e13686.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Restricting glycolysis impairs brown adipocyte glucose and oxygen consumption
Winther, Sally, Isidor, Marie Sophie, Basse, A. L., Skjoldborg, N., Cheung, A., Quistorff, B. & Hansen, Jacob B., 2018, In: American Journal of Physiology: Endocrinology and Metabolism. 314, 3, p. E214-E223 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Separate effects of glucagon like peptide-2 (GLP-2) and glucose-dependent insulinotropic polypeptide (GIP) on bone remodelling
Skov-Jeppesen, Kirsa, Svane, M., Martinussen, C., Gabe, M., Gasbjerg, Lærke Smidt, Madsbad, Sten, Holst, Jens Juul, Rosenkilde, Mette & Hartmann, Bolette, 2018, In: Diabetologia. 61, S1, p. S245-S245 501.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Separating "good" from "bad" faecal dysbiosis: evidence from two cross-sectional studies
Farup, P. G., Aasbrenn, M. & Valeur, J., 2018, In: BMC Obesity. 5, 10 p., 30.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sevoflurane Impairs Insulin Secretion and Tissue-Specific Glucose Uptake In Vivo
Høyer, K. F., Nielsen, Thomas Svava, Risis, S., Treebak, Jonas Thue & Jessen, N., 2018, In: Basic & Clinical Pharmacology & Toxicology. 123, 6, p. 732-738Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Single Cell Analysis Identifies the miRNA Expression Profile of a Subpopulation of Muscle Precursor Cells Unique to Humans With Type 2 Diabetes
Henriksen, T. I., Heywood, S. E., Hansen, N. S., Pedersen, Bente Klarlund, Schéele, Camilla Charlotte Nielsen & Nielsen, S., 2018, In: Frontiers in Physiology. 9, p. 1-13 13 p., 883.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Skeletal Muscle Insulin Sensitivity Show Circadian Rhythmicity Which Is Independent of Exercise Training Status
Basse, A. L., Kellezi, Emilie Dalbram, Larsson, L., Gerhart-Hines, Zach, Zierath, Juleen R & Treebak, Jonas Thue, 2018, In: Frontiers in Physiology. 9, p. 1-12 12 p., 1198.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Skeletal muscle O-GlcNAc transferase is important for muscle energy homeostasis and whole-body insulin sensitivity
Shi, H., Munk, A., Nielsen, T. S., Daughtry, M. R., Larsson, L., Li, S., Høyer, K. F., Geisler, H. W., Sulek, K., Kjøbsted, R., Fisher, T., Andersen, M. M., Shen, Z., Hansen, U. K., England, E. M., Cheng, Z., Højlund, K., Wojtaszewski, J., Yang, X., Hulver, M. W. & 3 others, , 2018, In: Molecular Metabolism. 11, p. 160-177 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
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The isoenzyme pattern of LDH does not play a physiological role; except perhaps during fast transitions in energy metabolism
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Determinants of plasma levels of proglucagon and the metabolic impact of glucagon receptor signalling: a UK Biobank study
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The interplay between birth weight and obesity in determining childhood and adolescent cardiometabolic risk
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