Novo Nordisk Foundation Center for Basic Metabolic Research

  1. 2021
  2. Published

    Investigating GIPR (ant)agonism: A structural analysis of GIP and its receptor

    Smit, F. X., van der Velden, W. J. C., Kizilkaya, Hüsün Sheyma, Nørskov, A., Lückmann, Michael, Hansen, T. N., wbf943, wbf943, Qvotrup, K., Frimurer, Thomas Michael & Rosenkilde, Mette, 2021, In: Structure. 29, 7, p. 679-693.e6 21 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Investigating the causal effect of maternal vitamin B12 and folate levels on offspring birthweight

    Moen, G., Beaumont, R. N., Grarup, N., Sommer, C., Shields, B. M., Lawlor, D. A., Freathy, R. M., Evans, D. M. & Warrington, N. M., 2021, In: International Journal of Epidemiology. 50, 1, p. 179-189 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Investigation of the specificity and mechanism of action of the ULK1/AMPK inhibitor SBI-0206965

    Ahwazi, Danial, Neopane, K., Markby, G. R., Kopietz, F., Ovens, A. J., Dall, M., Hassing, Anna Skab, Gräsle, P., Alshuweishi, Y., Treebak, Jonas Thue, Salt, I. P., Göransson, O., Zeqiraj, E., Scott, J. W. & Sakamoto, Kei, 2021, In: Biochemical Journal. 478, 15, p. 2977-2997 21 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Isolation and characterization of muscle stem cells, fibro-adipogenic progenitors, and macrophages from human skeletal muscle biopsies

    Jensen, J. B., Møller, A. B., Just, J., Mose, M., de Paoli, F. V., Billeskov, T. B., Fred, Rikard Göran, Pers, Tune H, Pedersen, S. B., Petersen, K. K., Bjerre, M., Farup, J. & Jessen, N., 2021, In: American Journal of Physiology - Cell Physiology. 321, 2, p. C257-C268 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published
  7. Published

    Large-scale association analyses identify host factors influencing human gut microbiome composition

    Kurilshikov, A., Medina-Gomez, C., Bacigalupe, R., Radjabzadeh, D., Wang, J., Demirkan, A., Le Roy, C. I., Raygoza Garay, J. A., Finnicum, C. T., Liu, X., Zhernakova, D. V., Bonder, M. J., Hansen, T. H., Frost, F., Rühlemann, M. C., Turpin, W., Moon, J. Y., Kim, H. N., Lüll, K., Barkan, E. & 84 others, Shah, S. A., Fornage, M., Szopinska-Tokov, J., Wallen, Z. D., Borisevich, D., Agreus, L., Andreasson, A., Bang, C., Bedrani, L., Bell, J. T., Bisgaard, H., Boehnke, M., Boomsma, D. I., Burk, R. D., Claringbould, A., Croitoru, K., Davies, G. E., van Duijn, C. M., Duijts, L., Falony, G., Fu, J., van der Graaf, A., Hansen, Torben, Homuth, G., Hughes, D. A., Ijzerman, R. G., Jackson, M. A., Jaddoe, V. W. V., Joossens, M., Jørgensen, T., Keszthelyi, D., Knight, R., Laakso, M., Laudes, M., Launer, L. J., Lieb, W., Lusis, A. J., Masclee, A. A. M., Moll, H. A., Mujagic, Z., Qibin, Q., Rothschild, D., Shin, H., Sørensen, Søren Johannes, Steves, C. J., Thorsen, Jonathan Jan Ilve, Timpson, N. J., Tito, R. Y., Vieira-Silva, S., Völker, U., Völzke, H., Võsa, U., Wade, K. H., Walter, S., Watanabe, K., Weiss, S., Weiss, F. U., Weissbrod, O., Westra, H. J., Willemsen, G., Payami, H., Jonkers, D. M. A. E., Arias Vasquez, A., de Geus, E. J. C., Meyer, K. A., Stokholm, Jakob, Segal, E., Org, E., Wijmenga, C., Kim, H. L., Kaplan, R. C., Spector, T. D., Uitterlinden, A. G., Rivadeneira, F., Franke, A., Lerch, M. M., Franke, L., Sanna, S., D’Amato, M., Pedersen, Oluf Borbye, Paterson, A. D., Kraaij, R., Raes, J. & Zhernakova, A., 2021, In: Nature Genetics. 53, p. 156-165 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Leaky Gut as a Potential Culprit for the Paradoxical Dysglycemic Response to Gastric Bypass-Associated Ileal Microbiota

    Hankir, M. K., Seyfried, F., Schellinger, I. N., Schlegel, N. & Arora, Tulika, 2021, In: Metabolites. 11, 3, 10 p., 153.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis

    Sveidahl Johansen, O., Ma, T., Hansen, J. B., Markussen, L. K., Schreiber, R., Reverte-Salisa, L., Dong, H., Christensen, D. P., Sun, W., Gnad, T., Karavaeva, I., Nielsen, T. S., Kooijman, S., Cero, C., Dmytriyeva, O., Shen, Y., Razzoli, M., O'Brien, S. L., Kuipers, E. N., Nielsen, C. H. & 31 others, Orchard, W., Willemsen, N., Jespersen, N. Z., Lundh, M., Sustarsic, E. G., Hallgren, C. M., Frost, M., McGonigle, S., Isidor, Marie Sophie, Broholm, C., Pedersen, Oluf Borbye, Hansen, Jacob B., Grarup, N., Hansen, Torben, Kjær, Andreas, Granneman, J. G., Babu, M. M., Calebiro, D., Nielsen, S., Rydén, M., Soccio, R., Rensen, P. C. N., Treebak, Jonas Thue, Schwartz, Thue W., Emanuelli, Brice, Bartolomucci, A., Pfeifer, A., Zechner, R., Schéele, Camilla Charlotte Nielsen, Mandrup, S. & Gerhart-Hines, Z., 2021, In: Cell. 184, 13, p. 3502-3518 + 50 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Liraglutide decreases postprandial fibroblast growth factor 19 and glucagon-like peptide 2, and increases postprandial cholecystokinin in individuals with obesity

    Bronden, A., Nerild, H. H., Nexoe-Larsen, C. C., Hellmann, P. H., Baekdal, M., Gether, I. M., Gillum, M. P., Hartmann, Bolette, Knudsen, L. B., Jacobsen, L. V., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina, Sonne, D. P. & Knop, Filip Krag, 2021, In: Diabetologia. 64, SUPPL 1, p. 94-94 177.

    Research output: Contribution to journalConference abstract in journalResearch

  11. Published

    Longitudinal plasma protein profiling of newly diagnosed type 2 diabetes

    Gummesson, A., Björnson, E., Fagerberg, L., Zhong, W., Tebani, A., Edfors, F., Schmidt, C., Lundqvist, A., Adiels, M., Bäckhed, F., Schwenk, J. M., Jansson, P. A., Uhlén, M. & Bergström, G., 2021, In: EBioMedicine. 63, 11 p., 103147.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Loss of Function Glucose-Dependent Insulinotropic Polypeptide Receptor Variants Are Associated With Alterations in BMI, Bone Strength and Cardiovascular Outcomes

    Kizilkaya, Hüsün Sheyma, Sørensen, Kimmie Vestergaard, Kibsgaard, C. J., Gasbjerg, Lærke Smidt, Hauser, Alexander Sebastian, wbf943, wbf943, Grarup, N. & Rosenkilde, Mette, 2021, In: Frontiers in Cell and Developmental Biology. 9, 12 p., 749607.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Lysates of Methylococcus capsulatus Bath induce a lean-like microbiota, intestinal FoxP3+RORγt+IL-17+ Tregs and improve metabolism

    Jensen, B. A. H., Holm, J. B., Larsen, I. S., von Burg, N., Derer, S., Sonne, S. B., Pærregaard, S. I., Damgaard, M. V., Indrelid, S. A., Rivollier, A., Agrinier, A. L., Sulek, K., Arnoldussen, Y. J., Fjære, E., Marette, A., Angell, I. L., Rudi, K., Treebak, J. T., Madsen, L., Åkesson, C. P. & 5 others, Agace, W., Sina, C., Kleiveland, C. R., Kristiansen, Karsten & Lea, T. E., 2021, In: Nature Communications. 12, 19 p., 1093.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Mapping the human genetic architecture of COVID-19

    Niemi, M. E. K., Karjalainen, J., Liao, R. G., Neale, B. M., Daly, M., Ganna, A., Pathak, G. A., Andrews, S. J., Kanai, M., Veerapen, K., Fernandez-Cadenas, I., Schulte, E. C., Striano, P., Marttila, M., Minica, C., Marouli, E., Karim, M. A., Wendt, F. R., Savage, J., Sloofman, L. & 41 others, Butler-Laporte, G., Kim, H., Kanoni, S., Okada, Y., Byun, J., Han, Y., Uddin, M. J., Smith, G. D., Willer, C. J., Buxbaum, J. D., Karjalainen, J., Mehtonen, J., Folkersen, L., Moltke, Ida, Hinney, A., Wang, C., Ellinghaus, D., Brunak, Søren, Castro, P., Guindo Martínez, Marta, Lee, J. Y., Loos, Ruth, Zhao, J. H., Sun, Y. V., Wang, B., Parker, R., Garcia, S. M., Smith, O., Davis, C., COVID-19 Host Genetics Initiative, C. H. G. I., 23andMe COVID-19 Team, 2. C. T., Norwegian SARS-CoV-2 Study Grp, N. S. S. G., Humanitas COVID-19 Task Force, H. C. T. F., Humanitas Gavazzeni COVID-19 Task, H. G. C. T., FHoGID, F., RegCOVID, R., P-PredictUs, P., SeroCOVID, S., CRiPSI, C., Genes & Hlth Res Team, G. &. H. R. T. & UCLA Hlth ATLAS Data Mart Working, U. H. A. D. M. W., 2021, In: Nature. 600, p. 472-477

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Mass-spectrometry-based proteomics reveals mitochondrial supercomplexome plasticity

    Gonzalez-Franquesa, A., Stocks, Ben Nicholas, Chubanava, Sabina, Hattel, H. B., Moreno Justicia, Roger, Peijs, Lone, Treebak, Jonas Thue, Zierath, Juleen R & Deshmukh, Atul Shahaji, 2021, In: Cell Reports. 35, 8, 20 p., 109180.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Maternal anxiety during pregnancy and newborn epigenome-wide DNA methylation

    Sammallahti, S., Cortes Hidalgo, A. P., Tuominen, S., Malmberg, A., Mulder, R. H., Brunst, K. J., Alemany, S., McBride, N. S., Yousefi, P., Heiss, J. A., McRae, N., Page, C. M., Jin, J., Pesce, G., Caramaschi, D., Rifas-Shiman, S. L., Koen, N., Adams, C. D., Magnus, M. C., Baiz, N. & 31 others, Ratanatharathorn, A., Czamara, D., Haberg, S. E., Colicino, E., Baccarelli, A. A., Cardenas, A., DeMeo, D. L., Lawlor, D. A., Relton, C. L., Felix, J. F., van IJzendoorn, M. H., Bakermans-Kranenburg, M. J., Kajantie, E., Raikkonen, K., Sunyer, J., Sharp, G. C., Houtepen, L. C., Nohr, E. A., Sørensen, Thorkild I.A., Tellez-Rojo, M. M., Wright, R. O., Annesi-Maesano, I., Wright, J., Hivert, M., Wright, R. J., Zar, H. J., Stein, D. J., London, S. J., Cecil, C. A. M., Tiemeier, H. & Lahti, J., 2021, In: Molecular Psychiatry. 26, p. 1832–1845 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Maternal cecal microbiota transfer rescues early-life antibiotic-induced enhancement of type 1 diabetes in mice

    Zhang, X. S., Yin, Y. S., Wang, J., Battaglia, T., Krautkramer, K., Li, W. V., Li, J., Brown, M., Zhang, M., Badri, M. H., Armstrong, A. J. S., Strauch, C. M., Wang, Z., Nemet, I., Altomare, N., Devlin, J. C., He, L., Morton, J. T., Chalk, J. A., Needles, K. & 9 others, Liao, V., Mount, J., Li, H., Ruggles, K. V., Bonneau, R. A., Dominguez-Bello, M. G., Bäckhed, F., Hazen, S. L. & Blaser, M. J., 2021, In: Cell Host and Microbe. 29, 8, p. 1249-1265.e9

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Maternal thyroid disease and adiposity in mother and child

    Andersen, S. L., Andersen, S., Liew, Z., Vestergaard, P., Lundbye-Christensen, S., Sørensen, Thorkild I.A. & Olsen, J., 2021, In: Clinical Endocrinology. 94, 3, p. 484-493 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Maximal fat oxidation rate is higher in fit women and unfit women with obesity, compared to normal weight unfit women

    Frandsen, J., Hansen, I. M. D., Wismann, J. F., Olsen, M. H., Brage-Andersen, M. R., Sahl, Ronni Eg, Hansen, M., Ingersen, Arthur, Modvig, J. L., Schmücker, M., brl298, brl298, Dela, Flemming, Larsen, Steen & Helge, Jørn Wulff, 2021, In: Journal of Clinical Endocrinology and Metabolism. 106, 11, p. E4389-E4399 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Mechanism-based inhibitors of SIRT2: structure–activity relationship, X-ray structures, target engagement, regulation of α-tubulin acetylation and inhibition of breast cancer cell migration

    Nielsen, A. L., Rajabi, N., Kudo, N., Jørgensen, Kathrine Lundø, Moreno Yruela, Carlos, Bæk, M., Fontenas, M., Lucidi, A., Madsen, A. S., Yoshida, M. & Olsen, Christian Adam, 2021, In: RSC Chemical Biology. 2, p. 612-626

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Metabolic consequences of obesity and type 2 diabetes: Balancing genes and environment for personalized care

    Pillon, N. J., Loos, R. J. F., Marshall, S. M. & Zierath, Juleen R, 2021, In: Cell. 184, 6, p. 1530-1544 15 p.

    Research output: Contribution to journalReviewResearchpeer-review

  22. Published

    Metformin Lowers Body Weight But Fails to Increase Insulin Sensitivity in Chronic Heart Failure Patients without Diabetes: a Randomized, Double-Blind, Placebo-Controlled Study

    Larsen, A. H., Wiggers, H., Dollerup, O. L., Jespersen, N. R., Hansson, N. H., Frokiaer, J., Brøsen, K., Norrelund, H., Bøtker, H. E., Møller, N. & Jessen, N., 2021, In: Cardiovascular Drugs and Therapy. 35, p. 491-503 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Metformin stimulates intestinal glycolysis and lactate release: A single-dose study of metformin in patients with intrahepatic portosystemic stent

    Rittig, N., Aagaard, N. K., Sundelin, E., Villadsen, G. E., Sandahl, T. D., Holst, Jens Juul, Hartmann, Bolette, Brøsen, K., Grønbaek, H. & Jessen, N., 2021, In: Clinical Pharmacology and Therapeutics. 110, 5, p. 1329-1336

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Microbial regulation of enteroendocrine cells

    Arora, Tulika, Vanslette, A. M., Hjorth, Siv Annegrethe & Backhed, F., 2021, In: Med. 2, 5, p. 553-570 18 p.

    Research output: Contribution to journalReviewResearchpeer-review

  25. Published

    Microbial regulation of hexokinase 2 links mitochondrial metabolism and cell death in colitis

    Hinrichsen, F., Hamm, J., Westermann, M., Schröder, L., Shima, K., Mishra, N., Walker, A., Sommer, N., Klischies, K., Prasse, D., Zimmermann, J., Kaiser, S., Bordoni, D., Fazio, A., Marinos, G., Laue, G., Imm, S., Tremaroli, V., Basic, M., Häsler, R. & 10 others, Schmitz, R. A., Krautwald, S., Wolf, A., Stecher, B., Schmitt-Kopplin, P., Kaleta, C., Rupp, J., Bäckhed, F., Rosenstiel, P. & Sommer, F., 2021, In: Cell Metabolism. 33, 12, p. 2355-2366.e8

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Molecular mechanism of ligand binding pathways and activation of the succinate receptor

    Iliyaz, Aslihan Shenol, Lückmann, Michael, Trauelsen, Mette, Frimurer, Thomas Michael & Schwartz, Thue W., 2021, In: European Biophysics Journal. 50, Suppl. 1, p. 160 1 p., P-234.

    Research output: Contribution to journalConference abstract in journalResearch

  27. Published

    Multi-ancestry genome-wide association study accounting for gene-psychosocial factor interactions identifies novel loci for blood pressure traits

    LifeLines Cohort Study, L. C. S., 2021, In: Human Genetics and Genomics Advances. 2, 1, 12 p., 100013.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure

    Wang, H., Noordam, R., Cade, B. E., Schwander, K., Winkler, T. W., Lee, J., Sung, Y. J., Bentley, A. R., Manning, A. K., Aschard, H., Kilpeläinen, T. O., Ilkov, M., Brown, M. R., Horimoto, A. R., Richard, M., Bartz, T. M., Vojinovic, D., Lim, E., Nierenberg, J. L., Liu, Y. & 105 others, Chitrala, K., Rankinen, T., Musani, S. K., Franceschini, N., Rauramaa, R., Alver, M., Zee, P. C., Harris, S. E., van der Most, P. J., Nolte, I. M., Munroe, P. B., Palmer, N. D., Kühnel, B., Weiss, S., Wen, W., Hall, K. A., Lyytikäinen, L., O'Connell, J., Eiriksdottir, G., Launer, L. J., de Vries, P. S., Arking, D. E., Chen, H., Boerwinkle, E., Krieger, J. E., Schreiner, P. J., Sidney, S., Shikany, J. M., Rice, K., Chen, Y. I., Gharib, S. A., Bis, J. C., Luik, A. I., Ikram, M. A., Uitterlinden, A. G., Amin, N., Xu, H., Levy, D., He, J., Lohman, K. K., Zonderman, A. B., Rice, T. K., Sims, M., Wilson, G., Sofer, T., Rich, S. S., Palmas, W., Yao, J., Guo, X., Rotter, J. I., Biermasz, N. R., Mook-Kanamori, D. O., Martin, L. W., Barac, A., Wallace, R. B., Gottlieb, D. J., Komulainen, P., Heikkinen, S., Mägi, R., Milani, L., Metspalu, A., Starr, J. M., Milaneschi, Y., Waken, R. J., Gao, C., Waldenberger, M., Peters, A., Strauch, K., Meitinger, T., Roenneberg, T., Völker, U., Dörr, M., Shu, X., Mukherjee, S., Hillman, D. R., Kähönen, M., Wagenknecht, L. E., Gieger, C., Grabe, H. J., Zheng, W., Palmer, L. J., Lehtimäki, T., Gudnason, V., Morrison, A. C., Pereira, A. C., Fornage, M., Psaty, B. M., van Duijn, C. M., Liu, C., Kelly, T. N., Evans, M. K., Bouchard, C., Fox, E. R., Kooperberg, C., Zhu, X., Lakka, T. A., Esko, T., North, K. E., Deary, I. J., Snieder, H., Penninx, B. W. J. H., Gauderman, W. J., Rao, D. C., Redline, S. & van Heemst, D., 2021, In: Molecular Psychiatry. 26, p. 6293-6304

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    MultiPep: a hierarchical deep learning approach for multi-label classification of peptide bioactivities

    Grønning, Alexander GB, Kacprowski, T. & Schéele, Camilla Charlotte Nielsen, 2021, In: Biology Methods and Protocols. 6, 1, 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Neprilysin Inhibition Increases Glucagon Levels in Humans and Mice With Potential Effects on Amino Acid Metabolism

    Kjeldsen, Sasha Alexandra Sampson, Hansen, L. H., Esser, N., Mongovin, S., Winther-Sørensen, Marie, Galsgaard, Katrine Douglas, Dal, Jenna Elizabeth Hunt, Kissow, Hannelouise, Ceutz, F. R., Terzic, D., Mark, P. D., Plomgaard, Peter Stendahl, Goetze, Jens P. , Goossens, G. H., Blaak, E. E., Deacon, Carolyn F., Rosenkilde, Mette, Zraika, S., Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2021, In: Endocrine Research. 5, 9, 15 p., bvab084.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    New Insights into Molecular Mechanisms Mediating Adaptation to Exercise: A Review Focusing on Mitochondrial Biogenesis, Mitochondrial Function, Mitophagy and Autophagy

    Roberts, F. L. & Markby, G. R., 2021, In: Cells. 10, 10, 29 p., 2639.

    Research output: Contribution to journalReviewResearchpeer-review

  32. Published

    No effect of dietary fish oil supplementation on the recruitment of brown and brite adipocytes in mice or humans under thermoneutral conditions

    Maurer, S. F., Dieckmann, S., Lund, Jens, Fromme, T., Hess, A. L., Colson, C., Kjølbæk, Louise, Astrup, A., Gillum, M. P., Larsen, L. H., Liebisch, G., Amri, E. & Klingenspor, M., 2021, In: Molecular Nutrition & Food Research. 65, 2, 15 p., 2000681.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    No effects of dapagliflozin, metformin or exercise on plasma glucagon concentrations in individuals with prediabetes: A post hoc analysis from the randomized controlled PRE-D trial

    Clemmensen, K. K. B., Blond, M. B., Amadid, H., Bruhn, L., Vistisen, D., Karstoft, K., Persson, F., Ried-Larsen, M., Holst, Jens Juul, Albrechtsen, Nicolai Jacob Wewer, Torekov, Signe Sørensen, Quist, J. S., Jorgensen, M. E. & Faerch, K., 2021, In: Diabetes, Obesity and Metabolism. 23, 2, p. 530-539

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Non-cell autonomous mechanisms control mitochondrial gene dysregulation in polycystic ovary syndrome

    Moreno-Asso, A., Altıntaş, Ali, McIlvenna, L. C., Patten, R. K., Botella, J., McAinch, A. J., Rodgers, R. J., Barrès, Romain & Stepto, N. K., 2021, In: Journal of Molecular Endocrinology. 68, 1, p. 63-76

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Non-linear interaction between physical activity and polygenic risk score of body mass index in Danish and Russian populations

    Borisevich, D., Schnurr, T. M., pjx571, pjx571, Rakitko, A., Ängquist, Lars, Ilinsky, V., Aadahl, Mette, Grarup, N., Pedersen, Oluf Borbye, Sørensen, Thorkild I.A. & Hansen, Torben, 2021, In: PLoS ONE. 16, 10, 16 p., e0258748.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Nonalcoholic Fatty Liver Disease and Cardiovascular Disease: Overlapping Mechanisms

    Møller, Søren, Kimer, N., Kronborg, T., Grandt, J., Hove, Jens Dahlgaard, Barløse, Mads Christian Johannes & Gluud, Lise Lotte, 2021, In: Seminars in Liver Disease. 41, 03, p. 235-247

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Novel Anti-inflammatory Treatments in Cirrhosis. A Literature-Based Study

    Kronborg, T. M., Lambert, Henriette Ytting, Hobolth, L., Møller, Søren & Kimer, N., 2021, In: Frontiers in Medicine. 8, 718896.

    Research output: Contribution to journalReviewResearchpeer-review

  38. Published

    Obesity treatment effect in Danish children and adolescents carrying Melanocortin-4 Receptor mutations

    Trier, C., Hollensted, M., Schnurr, T. M., Lund, Morten Asp Vonsild, Nielsen, T. R. H., Rui, G., Andersson, E. A., Svendstrup, M., Bille, D. S., Gjesing, A. P., Fonvig, Cilius Esmann, Frithioff-Bojsoe, C., Balslev-Harder, M., Quan, S., Gamborg, Michael Orland, Pedersen, Oluf Borbye, Ängquist, Lars, Holm, Jens-Christian & Hansen, Torben, 2021, In: International Journal of Obesity. 45, p. 66-76 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Ocular Surface Microbiota in Contact Lens Users and Contact-Lens-Associated Bacterial Keratitis

    Andersson, J., Vogt, J. K., Dalgaard, M. D., Pedersen, Oluf Borbye, Holmgaard, Kim & Heegaard, Steffen, 2021, In: Vision (Switzerland). 5, 2, 12 p., 27.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Ocular surface microbiota in patients with aqueous tear-deficient dry eye

    Andersson, J., Vogt, J. K., Dalgaard, M. D., Pedersen, Oluf Borbye, Holmgaard, Kim & Heegaard, Steffen, 2021, In: Ocular Surface. 19, p. 210-217

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Overweight in childhood of exclusively breastfed infants with a high weight at 5 months

    Morgen, C. S., Larsson, M. W., Ängquist, Lars, Sørensen, Thorkild I.A. & Michaelsen, Kim F., 2021, In: Maternal and Child Nutrition. 17, 1, 10 p., e13057.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Paracrine regulation of somatostatin secretion by insulin and glucagon in mouse pancreatic islets

    Svendsen, B. & Holst, Jens Juul, 2021, In: Diabetologia. 64, p. 142–151 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Parenteral nutrition impairs plasma bile acid and gut hormone responses to mixed meal testing in lean healthy men

    Meessen, E. C. E., Bakker, G. J., Nieuwdorp, M., Dallinga-Thie, G. M., Kemper, E. M., Olde Damink, S. W., Romijn, J. A., Hartmann, Bolette, Holst, Jens Juul, Knop, Filip Krag, Groen, A. K., Schaap, F. G. & Soeters, M. R., 2021, In: Clinical Nutrition. 40, 3, p. 1013-1021

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Perinatal exposure to nicotine alters spermatozoal DNA methylation near genes controlling nicotine action

    Altıntaş, Ali, Liu, J., Fabre, O., Chuang, T., Wang, Y., Sakurai, R., Chehabi, G. N., Barrès, Romain & Rehan, V. K., 2021, In: F A S E B Journal. 35, 7, e21702.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Perspectives on the role of brown adipose tissue in human body temperature and metabolism

    Schéele, Camilla Charlotte Nielsen, 2021, In: Cell Reports Medicine. 2, 10, 3 p., 100427.

    Research output: Contribution to journalEditorialResearch

  46. Published

    Pharmacokinetics of exogenous GIP(1-42) in C57Bl/6 mice; Extremely rapid degradation but marked variation between available assays

    Boer, G. A., Hartmann, Bolette & Holst, Jens Juul, 2021, In: Peptides. 136, 7 p., 170457.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Pharmacological but not physiological GDF15 suppresses feeding and the motivation to exercise

    Klein, A. B., Nicolaisen, T. S., Ørtenblad, N., Gejl, K. D., Jensen, R., Fritzen, A. M., Larsen, E. L., Karstoft, K., Poulsen, H. E., Morville, T., Sahl, R. E., Helge, J. W., Lund, J., Falk, S., Lyngbæk, M., Ellingsgaard, H., Pedersen, B. K., Lu, W., Finan, B., Jørgensen, S. B. & 5 others, Seeley, R. J., Kleinert, Maximilian, Kiens, Bente, Richter, Erik A. & Clemmensen, Christoffer, 2021, In: Nature Communications. 12, 9 p., 1041.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Physical activity attenuates postprandial hyperglycaemia in homozygous TBC1D4 loss-of-function mutation carriers

    Schnurr, T. M., Jørsboe, E., Chadt, A., Dahl-Petersen, I. K., Kristensen, Jonas Møller, Wojtaszewski, Jørgen F P, Springer, C., Bjerregaard, P., Brage, S., Pedersen, Oluf Borbye, Moltke, Ida, Grarup, N., Al-Hasani, H., Albrechtsen, Anders, Jørgensen, M. E. & Hansen, Torben, 2021, In: Diabetologia. 64, p. 1795-1804

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Plasma GDF15 levels are similar between subjects after bariatric surgery and matched controls and are unaffected by meals

    Martinussen, C., Svane, M. S., Bojsen-Møller, K. N., Jensen, Christian Zinck, Kristiansen, V. B., Bookout, A. L., Jorgensen, S. B., Holst, Jens Juul, Albrechtsen, Nicolai Jacob Wewer, Madsbad, Sten & Kuhre, Rune Ehrenreich, 2021, In: American Journal of Physiology: Endocrinology and Metabolism. p. E443-E452 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Plasma Imidazole Propionate Is Positively Correlated with Blood Pressure in Overweight and Obese Humans

    van Son, J., Serlie, M. J., Stahlman, M., Backhed, F., Nieuwdorp, M. & Aron-Wisnewsky, J., 2021, In: Nutrients. 13, 8, 8 p., 2706.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Plasma levels of glucagon but not GLP-1 are elevated in response to inflammation in humans

    Modrzynska, J., Klein, C. F., Iversen, Kasper, Bundgård, Henning, Hartmann, Bolette, Mose, M., Rittig, N., Møller, N., Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2021, In: Endocrine Connections. 10, 2, p. 205-213 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review